Dr Stuart Caldwell

  • Research Associate (Chemistry)

telephone: 01413306554
email: Stuart.Caldwell@glasgow.ac.uk

Publications

List by: Type | Date

Jump to: 2019 | 2018 | 2017 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008
Number of items: 28.

2019

Antonucci, S. et al. (2019) Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. Free Radical Biology and Medicine, 134, pp. 678-687. (doi:10.1016/j.freeradbiomed.2019.01.034) (PMID:30731114)

2018

Fazakerley, D. J. et al. (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. Journal of Biological Chemistry, 293(19), pp. 7315-7328. (doi:10.1074/jbc.RA117.001254) (PMID:29599292) (PMCID:PMC5950018)

Mills, E. L. et al. (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature, 5556, pp. 113-117. (doi:10.1038/nature25986) (PMID:29590092)

Cao, Z., Mitchell, L., Hsia, O., Scarpa, M., Caldwell, S. T., Alfred, A. D., Gennaris, A., Collet, J.-F., Hartley, R. C. and Bulleid, N. J. (2018) Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase. Biochemical Journal, 475, pp. 827-838. (doi:10.1042/BCJ20170929) (PMID:29420254) (PMCID:PMC6488974)

2017

Shchepinova, M. M. et al. (2017) MitoNeoD: a mitochondria-targeted superoxide probe. Cell Chemical Biology, 24(10), 1285-1298.e12. (doi:10.1016/j.chembiol.2017.08.003) (PMID:28890317)

2015

Caldwell, S. T., Cairns, A. G., Olson, M., Chalmers, S., Sandison, M., Mullen, W. , McCarron, J. G. and Hartley, R. C. (2015) Synthesis of an azido-tagged low affinity ratiometric calcium sensor. Tetrahedron, 71(51), pp. 9571-9578. (doi:10.1016/j.tet.2015.10.052) (PMID:26709317) (PMCID:PMC4660056)

2014

Caldwell, S.T. et al. (2014) Protein-mediated dethreading of a biotin-functionalised pseudorotaxane. Organic and Biomolecular Chemistry, 12(3), pp. 511-516. (doi:10.1039/C3OB41612G)

2013

Anamimoghadam, O., Symes, M. D. , Busche, C., Long, D.-L. , Caldwell, S. T., Flors, C., Nonell, S., Cronin, L. and Bucher, G. (2013) Naphthoxanthenyl, a new stable phenalenyl type radical stabilized by electronic effects. Organic Letters, 15(12), pp. 2970-2973. (doi:10.1021/ol401117g)

McQuaker, S. J., Quinlan, C. L., Caldwell, S. T., Brand, M. D. and Hartley, R. C. (2013) A prototypical small-molecule modulator uncouples mitochondria in response to endogenous hydrogen peroxide production. ChemBioChem, 14(8), pp. 993-1000. (doi:10.1002/cbic.201300115) (PMID:23640856) (PMCID:PMC3743171)

Pauszek, R. F., Kodali, G., Caldwell, S. T., Fitzpatrick, B., Zainalabdeen, N. Y., Cooke, G. , Rotello, V. M. and Stanley, R. J. (2013) Excited state charge redistribution and dynamics in the donor-π-acceptor flavin derivative ABFL. Journal of Physical Chemistry B, 117(49), pp. 15684-15694. (doi:10.1021/jp406420h)

2012

Caldwell, S.T., McPhail, D.B., Duthie, G.D. and Hartley, R.C. (2012) Synthesis of polyhydroxylated flavonoids bearing a lipophilic decyl tail as potential therapeutic antioxidants. Canadian Journal of Chemistry = Journal canadien de chimie, 90(1), pp. 23-33. (doi:10.1139/V11-087)

Chalmers, S., Caldwell, S. T., Quin, C., Prime, T. A., James, A. M., Cairns, A. G., Murphy, M. P., McCarron, J. G. and Hartley, R. C. (2012) Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. Journal of the American Chemical Society, 134(2), pp. 758-761. (doi:10.1021/ja2077922) (PMID:22239373) (PMCID:PMC3260739)

Omar, M.H., Mullen, W. , Stalmach, A. , Auger, C., Rouanet, J.-M., Teissedre, P.-L., Caldwell, S.T., Hartley, R.C. and Crozier, A. (2012) Absorption, disposition, metabolism, and excretion of [3-14C]caffeic acid in rats. Journal of Agricultural and Food Chemistry, 60(20), pp. 5205-5214. (doi:10.1021/jf3001185)

2011

McDonald, N.A., Subramani, C., Caldwell, S.T., Zainalabdeen, N.Y., Cooke, G. and Rotello, V.M. (2011) Simultaneous hydrogen bonding and π-stacking interactions between flavin/porphyrin host–guest syst. Tetrahedron Letters, 52(17), pp. 2107-2110. (doi:10.1016/j.tetlet.2010.11.004)

2010

Figlus, M., Caldwell, S.T., Walas, D., Yesilbag, G., Cooke, G. , Kocovsky, P., Malkov, A.V. and Sanyal, A. (2010) Dendron-anchored organocatalysts: the asymmetric reduction of imines with trichlorosilane, catalysed by an amino acid-derived formamide appended to a dendron. Organic and Biomolecular Chemistry, 8(1), pp. 137-141. (doi:10.1039/b916601g)

Siddle, J. S., Batsanov, A. S., Caldwell, S. T., Cooke, G. and Bryce, M. R. (2010) Divergent synthesis of arylated pyridin-2(1H)-one derivatives via metal-catalysed cross-coupling processes. Tetrahedron, 66(32), pp. 6138-6149. (doi:10.1016/j.tet.2010.05.108)

Spreull, J.M. et al. (2010) Highly stable tetrathiafulvalene radical dimers in [3]catenanes. Nature Chemistry, 2(10), pp. 870-879. (doi:10.1038/nchem.749)

2009

Bigot, J. et al. (2009) LCST: a powerful tool to control complexation between a dialkoxynaphthalene-functionalised poly(N-isopropylacrylamide) and CBPQT(4+) in water. Chemical Communications(35), pp. 5266-5268. (doi:10.1039/b910856d)

Caldwell, S. T., Farrugia, L. J., Hewage, S. G., Kryvokhyzha, N., Rotello, V. M. and Cooke, G. (2009) Model systems for flavoenzyme activity: an investigation of the role functionality attached to the C(7) position of the flavin unit has on redox and molecular recognition properties. Chemical Communications(11), pp. 1350-1352. (doi:10.1039/b900269n)

Malkov, A. V., Figlus, M., Cooke, G. , Caldwell, S.T., Rabani, G., Prestly, M. R. and Kocovsky, P. (2009) Organocatalysts immobilised onto gold nanoparticles: application in the asymmetric reduction of imines with trichlorosilane. Organic and Biomolecular Chemistry, 7(9), pp. 1878-1883. (doi:10.1039/b821391g)

Patra, D., Pagliuca, C., Subramani, C., Samanta, B., Agasti, S. S., Zainalabdeen, N., Caldwell, S. T., Cooke, G. and Rotello, V. M. (2009) Molecular recognition at the liquid-liquid interface of colloidal microcapsules. Chemical Communications(28), pp. 4248-4250. (doi:10.1039/b906458c)

2008

Jordan, B.J. et al. (2008) 'Lock and key' control of optical properties in a push-pull system. Chemical Communications(14), pp. 1653-1655. (doi:10.1039/b718015b)

Agasti, S. S., Caldwell, S. T., Cooke, G. , Jordan, B. J., Kennedy, A., Kryvokhyzha, N., Rabani, G., Rana, S., Sanyal, A. and Rotello, V. M. (2008) Dendron-based model systems for flavoenzyme activity: towards a new class of synthetic flavoenzyme. Chemical Communications(35), pp. 4123-4125. (doi:10.1039/b809568j)

Caldwell, S. T., Cooke, G. , Cooper, A., Nutley, M., Rabani, G., Rotello, V., Smith, B. O. and Woisel, P. (2008) Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT(4+). Chemical Communications(23), pp. 2650-2652. (doi:10.1039/b803856b)

Caldwell, S. T., Cooke, G. , Fitzpatrick, B., Long, D.L. , Rabani, G. and Rotello, V. M. (2008) A flavin-based [2]catenane. Chemical Communications(45), pp. 5912-5914. (doi:10.1039/b813779j)

Caldwell, S. T., Cooke, G. , Hewage, S. G., Mabruk, S., Rabani, G., Rotello, V., Smith, B.O. , Subramani, C. and Woisel, P. (2008) Model systems for flavoenzyme activity: intramolecular self-assembly of a flavin derivative via hydrogen bonding and aromatic interactions. Chemical Communications(35), pp. 4126-4128. (doi:10.1039/b809762c)

Jordan, B. J., Ofir, Y., Patra, D., Caldwell, S. T., Kennedy, A., Joubanian, S., Rabani, G., Cooke, G. and Rotello, V. M. (2008) Controlled Self-Assembly of Organic Nanowires and Platelets Using Dipolar and Hydrogen-Bonding Interactions. Small, 4(11), pp. 2074-2078. (doi:10.1002/smll.200800811)

Mullen, W. , Rouanet, J.-M., Auger, C., Teissèdre, P.-L., Caldwell, S.T., Hartley, R.C. , Lean, M.E.J. , Edwards, C.A. and Crozier, A. (2008) Bioavailability of [2-14C]Quercetin-4′-glucoside in rats. Journal of Agricultural and Food Chemistry, 56(24), pp. 12127-12137. (doi:10.1021/jf802754s)

This list was generated on Sat Jul 20 20:20:38 2019 BST.
Jump to: Articles
Number of items: 28.

Articles

Antonucci, S. et al. (2019) Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. Free Radical Biology and Medicine, 134, pp. 678-687. (doi:10.1016/j.freeradbiomed.2019.01.034) (PMID:30731114)

Fazakerley, D. J. et al. (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. Journal of Biological Chemistry, 293(19), pp. 7315-7328. (doi:10.1074/jbc.RA117.001254) (PMID:29599292) (PMCID:PMC5950018)

Mills, E. L. et al. (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature, 5556, pp. 113-117. (doi:10.1038/nature25986) (PMID:29590092)

Cao, Z., Mitchell, L., Hsia, O., Scarpa, M., Caldwell, S. T., Alfred, A. D., Gennaris, A., Collet, J.-F., Hartley, R. C. and Bulleid, N. J. (2018) Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase. Biochemical Journal, 475, pp. 827-838. (doi:10.1042/BCJ20170929) (PMID:29420254) (PMCID:PMC6488974)

Shchepinova, M. M. et al. (2017) MitoNeoD: a mitochondria-targeted superoxide probe. Cell Chemical Biology, 24(10), 1285-1298.e12. (doi:10.1016/j.chembiol.2017.08.003) (PMID:28890317)

Caldwell, S. T., Cairns, A. G., Olson, M., Chalmers, S., Sandison, M., Mullen, W. , McCarron, J. G. and Hartley, R. C. (2015) Synthesis of an azido-tagged low affinity ratiometric calcium sensor. Tetrahedron, 71(51), pp. 9571-9578. (doi:10.1016/j.tet.2015.10.052) (PMID:26709317) (PMCID:PMC4660056)

Caldwell, S.T. et al. (2014) Protein-mediated dethreading of a biotin-functionalised pseudorotaxane. Organic and Biomolecular Chemistry, 12(3), pp. 511-516. (doi:10.1039/C3OB41612G)

Anamimoghadam, O., Symes, M. D. , Busche, C., Long, D.-L. , Caldwell, S. T., Flors, C., Nonell, S., Cronin, L. and Bucher, G. (2013) Naphthoxanthenyl, a new stable phenalenyl type radical stabilized by electronic effects. Organic Letters, 15(12), pp. 2970-2973. (doi:10.1021/ol401117g)

McQuaker, S. J., Quinlan, C. L., Caldwell, S. T., Brand, M. D. and Hartley, R. C. (2013) A prototypical small-molecule modulator uncouples mitochondria in response to endogenous hydrogen peroxide production. ChemBioChem, 14(8), pp. 993-1000. (doi:10.1002/cbic.201300115) (PMID:23640856) (PMCID:PMC3743171)

Pauszek, R. F., Kodali, G., Caldwell, S. T., Fitzpatrick, B., Zainalabdeen, N. Y., Cooke, G. , Rotello, V. M. and Stanley, R. J. (2013) Excited state charge redistribution and dynamics in the donor-π-acceptor flavin derivative ABFL. Journal of Physical Chemistry B, 117(49), pp. 15684-15694. (doi:10.1021/jp406420h)

Caldwell, S.T., McPhail, D.B., Duthie, G.D. and Hartley, R.C. (2012) Synthesis of polyhydroxylated flavonoids bearing a lipophilic decyl tail as potential therapeutic antioxidants. Canadian Journal of Chemistry = Journal canadien de chimie, 90(1), pp. 23-33. (doi:10.1139/V11-087)

Chalmers, S., Caldwell, S. T., Quin, C., Prime, T. A., James, A. M., Cairns, A. G., Murphy, M. P., McCarron, J. G. and Hartley, R. C. (2012) Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. Journal of the American Chemical Society, 134(2), pp. 758-761. (doi:10.1021/ja2077922) (PMID:22239373) (PMCID:PMC3260739)

Omar, M.H., Mullen, W. , Stalmach, A. , Auger, C., Rouanet, J.-M., Teissedre, P.-L., Caldwell, S.T., Hartley, R.C. and Crozier, A. (2012) Absorption, disposition, metabolism, and excretion of [3-14C]caffeic acid in rats. Journal of Agricultural and Food Chemistry, 60(20), pp. 5205-5214. (doi:10.1021/jf3001185)

McDonald, N.A., Subramani, C., Caldwell, S.T., Zainalabdeen, N.Y., Cooke, G. and Rotello, V.M. (2011) Simultaneous hydrogen bonding and π-stacking interactions between flavin/porphyrin host–guest syst. Tetrahedron Letters, 52(17), pp. 2107-2110. (doi:10.1016/j.tetlet.2010.11.004)

Figlus, M., Caldwell, S.T., Walas, D., Yesilbag, G., Cooke, G. , Kocovsky, P., Malkov, A.V. and Sanyal, A. (2010) Dendron-anchored organocatalysts: the asymmetric reduction of imines with trichlorosilane, catalysed by an amino acid-derived formamide appended to a dendron. Organic and Biomolecular Chemistry, 8(1), pp. 137-141. (doi:10.1039/b916601g)

Siddle, J. S., Batsanov, A. S., Caldwell, S. T., Cooke, G. and Bryce, M. R. (2010) Divergent synthesis of arylated pyridin-2(1H)-one derivatives via metal-catalysed cross-coupling processes. Tetrahedron, 66(32), pp. 6138-6149. (doi:10.1016/j.tet.2010.05.108)

Spreull, J.M. et al. (2010) Highly stable tetrathiafulvalene radical dimers in [3]catenanes. Nature Chemistry, 2(10), pp. 870-879. (doi:10.1038/nchem.749)

Bigot, J. et al. (2009) LCST: a powerful tool to control complexation between a dialkoxynaphthalene-functionalised poly(N-isopropylacrylamide) and CBPQT(4+) in water. Chemical Communications(35), pp. 5266-5268. (doi:10.1039/b910856d)

Caldwell, S. T., Farrugia, L. J., Hewage, S. G., Kryvokhyzha, N., Rotello, V. M. and Cooke, G. (2009) Model systems for flavoenzyme activity: an investigation of the role functionality attached to the C(7) position of the flavin unit has on redox and molecular recognition properties. Chemical Communications(11), pp. 1350-1352. (doi:10.1039/b900269n)

Malkov, A. V., Figlus, M., Cooke, G. , Caldwell, S.T., Rabani, G., Prestly, M. R. and Kocovsky, P. (2009) Organocatalysts immobilised onto gold nanoparticles: application in the asymmetric reduction of imines with trichlorosilane. Organic and Biomolecular Chemistry, 7(9), pp. 1878-1883. (doi:10.1039/b821391g)

Patra, D., Pagliuca, C., Subramani, C., Samanta, B., Agasti, S. S., Zainalabdeen, N., Caldwell, S. T., Cooke, G. and Rotello, V. M. (2009) Molecular recognition at the liquid-liquid interface of colloidal microcapsules. Chemical Communications(28), pp. 4248-4250. (doi:10.1039/b906458c)

Jordan, B.J. et al. (2008) 'Lock and key' control of optical properties in a push-pull system. Chemical Communications(14), pp. 1653-1655. (doi:10.1039/b718015b)

Agasti, S. S., Caldwell, S. T., Cooke, G. , Jordan, B. J., Kennedy, A., Kryvokhyzha, N., Rabani, G., Rana, S., Sanyal, A. and Rotello, V. M. (2008) Dendron-based model systems for flavoenzyme activity: towards a new class of synthetic flavoenzyme. Chemical Communications(35), pp. 4123-4125. (doi:10.1039/b809568j)

Caldwell, S. T., Cooke, G. , Cooper, A., Nutley, M., Rabani, G., Rotello, V., Smith, B. O. and Woisel, P. (2008) Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT(4+). Chemical Communications(23), pp. 2650-2652. (doi:10.1039/b803856b)

Caldwell, S. T., Cooke, G. , Fitzpatrick, B., Long, D.L. , Rabani, G. and Rotello, V. M. (2008) A flavin-based [2]catenane. Chemical Communications(45), pp. 5912-5914. (doi:10.1039/b813779j)

Caldwell, S. T., Cooke, G. , Hewage, S. G., Mabruk, S., Rabani, G., Rotello, V., Smith, B.O. , Subramani, C. and Woisel, P. (2008) Model systems for flavoenzyme activity: intramolecular self-assembly of a flavin derivative via hydrogen bonding and aromatic interactions. Chemical Communications(35), pp. 4126-4128. (doi:10.1039/b809762c)

Jordan, B. J., Ofir, Y., Patra, D., Caldwell, S. T., Kennedy, A., Joubanian, S., Rabani, G., Cooke, G. and Rotello, V. M. (2008) Controlled Self-Assembly of Organic Nanowires and Platelets Using Dipolar and Hydrogen-Bonding Interactions. Small, 4(11), pp. 2074-2078. (doi:10.1002/smll.200800811)

Mullen, W. , Rouanet, J.-M., Auger, C., Teissèdre, P.-L., Caldwell, S.T., Hartley, R.C. , Lean, M.E.J. , Edwards, C.A. and Crozier, A. (2008) Bioavailability of [2-14C]Quercetin-4′-glucoside in rats. Journal of Agricultural and Food Chemistry, 56(24), pp. 12127-12137. (doi:10.1021/jf802754s)

This list was generated on Sat Jul 20 20:20:38 2019 BST.