Dr Stuart Caldwell

  • Research Associate (School of Chemistry)

telephone: 01413306554
email: Stuart.Caldwell@glasgow.ac.uk

Chemistry, Joseph Black Building, Glasgow G12 8QQ

Import to contacts

ORCID iDhttps://orcid.org/0000-0003-1604-3462

Research interests

Research groups

Publications

List by: Type | Date

Jump to: 2025 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2000
Number of items: 45.

2025

Eaglesfield, Ross, Fernandez-Vizarra, Erika, Lacko, Erik, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Sloan, Nikki L., Siciarz, Daniel, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Tokatlidis, Kostas ORCID logoORCID: https://orcid.org/0000-0001-6295-8183 (2025) Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter. Redox Biology, 80, 103502. (doi: 10.1016/j.redox.2025.103502) (PMID:39864323) (PMCID:PMC11802384)

2023

Uno, Shinpei, Harkiss, Alexander H., Chowdhury, Roy, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Prime, Tracy A., James, Andrew M., Gallagher, Brendan, Prudent, Julien, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Murphy, Michael P. (2023) Incorporating a polyethyleneglycol linker to enhance the hydrophilicity of mitochondria‐targeted triphenylphosphonium constructs. ChemBioChem, 24(11), e202200774. (doi: 10.1002/cbic.202200774) (PMID:36917207) (PMCID:PMC10946768)

2022

Miljkovic, J. L. et al. (2022) Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury. Redox Biology, 55, 102429. (doi: 10.1016/j.redox.2022.102429) (PMID:35961099) (PMCID:PMC9382561)

Prag, H. A. et al. (2022) Ester prodrugs of malonate with enhanced intracellular delivery protect against cardiac ischemia-reperfusion injury in vivo. Cardiovascular Drugs and Therapy, 36(1), pp. 1-13. (doi: 10.1007/s10557-020-07033-6) (PMID:32648168) (PMCID:PMC8770414)

2021

Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, O'Byrne, Sean, Wilson, Calum, Cvetko, Filip, Murphy, Michael P., McCarron, John G. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2021) Photoactivated release of membrane impermeant sulfonates inside cells. Chemical Communications, 57(32), pp. 3917-3920. (doi: 10.1039/D0CC07713E) (PMID:33871501) (PMCID:PMC7611313)

Gaddale Devanna, K. K. et al. (2021) Tetra-arylborate lipophilic anions as targeting groups. Chemical Communications, 57(25), pp. 3147-3150. (doi: 10.1039/D0CC07924C) (PMID:33634803) (PMCID:PMC8062962)

Cvetko, Filip, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Higgins, Maureen, Suzuki, Takafumi, Yamamoto, Masayuki, Prag, Hiran A., Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405, Dinkova-Kostova, Albena and Murphy, Michael P. (2021) Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. Journal of Biological Chemistry, 296, 100169. (doi: 10.1074/jbc.RA120.016551) (PMID:33298526) (PMCID:PMC7948991)

Tan, S. M. et al. (2021) Targeting methylglyoxal in diabetic kidney disease using the mitochondria-targeted compound MitoGamide. Nutrients, 13(5), 1457. (doi: 10.3390/nu13051457) (PMID:33922959) (PMCID:PMC8145135)

2020

Park, M. et al. (2020) Confirmation of the cardioprotective effect of MitoGamide in the diabetic heart. Cardiovascular Drugs and Therapy, 34, pp. 823-834. (doi: 10.1007/s10557-020-07086-7) (PMID:32979176)

Pala, Laura, Senn, Hans M. ORCID logoORCID: https://orcid.org/0000-0001-8232-5957, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Prime, Tracey A., Warrington, Stefan, Bright, Thomas P., Prag, Hiran A., Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374, Murphy, Michael and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2020) Enhancing the mitochondrial uptake of phosphonium cations by carboxylic acid incorporation. Frontiers in Chemistry, 8, 783. (doi: 10.3389/fchem.2020.00783)

Prag, Hiran A., Kula-Alwar, Duvaraka, Pala, Laura, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Beach, Timothy E., James, Andrew M., Saeb-Parsy, Kourosh, Krieg, Thomas, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Murphy, Michael P. (2020) Selective delivery of dicarboxylates to mitochondria by conjugation to a lipophilic cation via a cleavable linker. Molecular Pharmaceutics, 17(9), pp. 3526-3540. (doi: 10.1021/acs.molpharmaceut.0c00533) (PMID:32692564) (PMCID:PMC7482397)

Burger, Nils, Logan, Angela, Prime, Tracy A., Mottahedin, Amin, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Krieg, Thomas, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405, James, Andrew M. and Murphy, Michael P. (2020) A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo. Free Radical Biology and Medicine, 147, pp. 37-47. (doi: 10.1016/j.freeradbiomed.2019.11.028) (PMID:31811922) (PMCID:PMC6975167)

2019

Tate, M. et al. (2019) The mitochondria-targeted methylglyoxal sequestering compound, MitoGamide, is cardioprotective in the diabetic heart. Cardiovascular Drugs and Therapy, 33(6), pp. 669-674. (doi: 10.1007/s10557-019-06914-9) (PMID:31654171) (PMCID:PMC6994445)

Martin, J. et al. (2019) Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nature Metabolism, 1(10), pp. 966-974. (doi: 10.1038/s42255-019-0115-y)

Antonucci, S. et al. (2019) Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. Free Radical Biology and Medicine, 134, pp. 678-687. (doi: 10.1016/j.freeradbiomed.2019.01.034) (PMID:30731114)

Booty, L. M. et al. (2019) Selective disruption of mitochondrial thiol redox state in cells and in vivo. Cell Chemical Biology, 26(3), 449-461.e8. (doi: 10.1016/j.chembiol.2018.12.002) (PMID:30713096) (PMCID:PMC6436940)

2018

Fazakerley, D. J. et al. (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. Journal of Biological Chemistry, 293(19), pp. 7315-7328. (doi: 10.1074/jbc.RA117.001254) (PMID:29599292) (PMCID:PMC5950018)

Mills, E. L. et al. (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature, 5556, pp. 113-117. (doi: 10.1038/nature25986) (PMID:29590092) (PMCID:PMC6047741)

Cao, Zhenbo, Mitchell, Lorna, Hsia, Oliver, Scarpa, Miriam, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Alfred, Arina D., Gennaris, Alexandra, Collet, Jean-Francois, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Bulleid, Neil J. ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2018) Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase. Biochemical Journal, 475, pp. 827-838. (doi: 10.1042/BCJ20170929) (PMID:29420254) (PMCID:PMC6488974)

2017

Shchepinova, M. M. et al. (2017) MitoNeoD: a mitochondria-targeted superoxide probe. Cell Chemical Biology, 24(10), 1285-1298.e12. (doi: 10.1016/j.chembiol.2017.08.003) (PMID:28890317) (PMCID:PMC6278870)

2015

Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cairns, Andrew G., Olson, Marnie, Chalmers, Susan, Sandison, Mairi, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, McCarron, John G. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2015) Synthesis of an azido-tagged low affinity ratiometric calcium sensor. Tetrahedron, 71(51), pp. 9571-9578. (doi: 10.1016/j.tet.2015.10.052) (PMID:26709317) (PMCID:PMC4660056)

2014

Caldwell, S.T. et al. (2014) Protein-mediated dethreading of a biotin-functionalised pseudorotaxane. Organic and Biomolecular Chemistry, 12(3), pp. 511-516. (doi: 10.1039/C3OB41612G) (PMID:24280954)

2013

Anamimoghadam, Ommid, Symes, Mark D. ORCID logoORCID: https://orcid.org/0000-0001-8067-5240, Busche, Christoph ORCID logoORCID: https://orcid.org/0000-0002-3493-2020, Long, De-Liang ORCID logoORCID: https://orcid.org/0000-0003-3241-2379, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Flors, Cristina, Nonell, Santi, Cronin, Leroy ORCID logoORCID: https://orcid.org/0000-0001-8035-5757 and Bucher, Goetz ORCID logoORCID: https://orcid.org/0000-0002-5478-8265 (2013) Naphthoxanthenyl, a new stable phenalenyl type radical stabilized by electronic effects. Organic Letters, 15(12), pp. 2970-2973. (doi: 10.1021/ol401117g)

McQuaker, Stephen J., Quinlan, Casey L., Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Brand, Martin D. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2013) A prototypical small-molecule modulator uncouples mitochondria in response to endogenous hydrogen peroxide production. ChemBioChem, 14(8), pp. 993-1000. (doi: 10.1002/cbic.201300115) (PMID:23640856) (PMCID:PMC3743171)

Pauszek, Raymond F., Kodali, Goutham, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Fitzpatrick, Brian, Zainalabdeen, Nada Y., Cooke, Graeme ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Rotello, Vincent M. and Stanley, Robert J. (2013) Excited state charge redistribution and dynamics in the donor-π-acceptor flavin derivative ABFL. Journal of Physical Chemistry B, 117(49), pp. 15684-15694. (doi: 10.1021/jp406420h)

2012

Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, McPhail, D.B., Duthie, G.D. and Hartley, R.C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2012) Synthesis of polyhydroxylated flavonoids bearing a lipophilic decyl tail as potential therapeutic antioxidants. Canadian Journal of Chemistry = Journal canadien de chimie, 90(1), pp. 23-33. (doi: 10.1139/V11-087)

Chalmers, Susan, Caldwell, Stuart T ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Quin, Caroline, Prime, Tracy A., James, Andrew M., Cairns, Andrew G., Murphy, Michael P, McCarron, John G. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2012) Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. Journal of the American Chemical Society, 134(2), pp. 758-761. (doi: 10.1021/ja2077922) (PMID:22239373) (PMCID:PMC3260739)

Omar, M.H., Mullen, W. ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Stalmach, A. ORCID logoORCID: https://orcid.org/0000-0003-4491-654X, Auger, C., Rouanet, J.-M., Teissedre, P.-L., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Hartley, R.C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Crozier, A. (2012) Absorption, disposition, metabolism, and excretion of [3-14C]caffeic acid in rats. Journal of Agricultural and Food Chemistry, 60(20), pp. 5205-5214. (doi: 10.1021/jf3001185)

2011

McDonald, N.A., Subramani, C., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Zainalabdeen, N.Y., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Rotello, V.M. (2011) Simultaneous hydrogen bonding and π-stacking interactions between flavin/porphyrin host–guest syst. Tetrahedron Letters, 52(17), pp. 2107-2110. (doi: 10.1016/j.tetlet.2010.11.004)

2010

Figlus, M., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Walas, D., Yesilbag, G., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Kocovsky, P., Malkov, A.V. and Sanyal, A. (2010) Dendron-anchored organocatalysts: the asymmetric reduction of imines with trichlorosilane, catalysed by an amino acid-derived formamide appended to a dendron. Organic and Biomolecular Chemistry, 8(1), pp. 137-141. (doi: 10.1039/b916601g)

Siddle, J. S., Batsanov, A. S., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Bryce, M. R. (2010) Divergent synthesis of arylated pyridin-2(1H)-one derivatives via metal-catalysed cross-coupling processes. Tetrahedron, 66(32), pp. 6138-6149. (doi: 10.1016/j.tet.2010.05.108)

Spreull, J.M. et al. (2010) Highly stable tetrathiafulvalene radical dimers in [3]catenanes. Nature Chemistry, 2(10), pp. 870-879. (doi: 10.1038/nchem.749)

2009

Bigot, J. et al. (2009) LCST: a powerful tool to control complexation between a dialkoxynaphthalene-functionalised poly(N-isopropylacrylamide) and CBPQT(4+) in water. Chemical Communications(35), pp. 5266-5268. (doi: 10.1039/b910856d)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Farrugia, L. J., Hewage, S. G., Kryvokhyzha, N., Rotello, V. M. and Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 (2009) Model systems for flavoenzyme activity: an investigation of the role functionality attached to the C(7) position of the flavin unit has on redox and molecular recognition properties. Chemical Communications(11), pp. 1350-1352. (doi: 10.1039/b900269n)

Malkov, A. V., Figlus, M., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Rabani, G., Prestly, M. R. and Kocovsky, P. (2009) Organocatalysts immobilised onto gold nanoparticles: application in the asymmetric reduction of imines with trichlorosilane. Organic and Biomolecular Chemistry, 7(9), pp. 1878-1883. (doi: 10.1039/b821391g)

Patra, D., Pagliuca, C., Subramani, C., Samanta, B., Agasti, S. S., Zainalabdeen, N., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Rotello, V. M. (2009) Molecular recognition at the liquid-liquid interface of colloidal microcapsules. Chemical Communications(28), pp. 4248-4250. (doi: 10.1039/b906458c)

2008

Jordan, B.J. et al. (2008) 'Lock and key' control of optical properties in a push-pull system. Chemical Communications(14), pp. 1653-1655. (doi: 10.1039/b718015b)

Agasti, S. S., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Jordan, B. J., Kennedy, A., Kryvokhyzha, N., Rabani, G., Rana, S., Sanyal, A. and Rotello, V. M. (2008) Dendron-based model systems for flavoenzyme activity: towards a new class of synthetic flavoenzyme. Chemical Communications(35), pp. 4123-4125. (doi: 10.1039/b809568j)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Cooper, A., Nutley, M., Rabani, G., Rotello, V., Smith, B. O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168 and Woisel, P. (2008) Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT(4+). Chemical Communications(23), pp. 2650-2652. (doi: 10.1039/b803856b)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Fitzpatrick, B., Long, D.L. ORCID logoORCID: https://orcid.org/0000-0003-3241-2379, Rabani, G. and Rotello, V. M. (2008) A flavin-based [2]catenane. Chemical Communications(45), pp. 5912-5914. (doi: 10.1039/b813779j)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Hewage, S. G., Mabruk, S., Rabani, G., Rotello, V., Smith, B.O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168, Subramani, C. and Woisel, P. (2008) Model systems for flavoenzyme activity: intramolecular self-assembly of a flavin derivative via hydrogen bonding and aromatic interactions. Chemical Communications(35), pp. 4126-4128. (doi: 10.1039/b809762c)

Jordan, B. J., Ofir, Y., Patra, D., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Kennedy, A., Joubanian, S., Rabani, G., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Rotello, V. M. (2008) Controlled Self-Assembly of Organic Nanowires and Platelets Using Dipolar and Hydrogen-Bonding Interactions. Small, 4(11), pp. 2074-2078. (doi: 10.1002/smll.200800811)

Mullen, W. ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Rouanet, J.-M., Auger, C., Teissèdre, P.-L., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Hartley, R.C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405, Lean, M.E.J. ORCID logoORCID: https://orcid.org/0000-0003-2216-0083, Edwards, C.A. ORCID logoORCID: https://orcid.org/0000-0003-0406-918X and Crozier, A. (2008) Bioavailability of [2-14C]Quercetin-4′-glucoside in rats. Journal of Agricultural and Food Chemistry, 56(24), pp. 12127-12137. (doi: 10.1021/jf802754s)

2000

Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Crozier, Alan and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2000) Isotopic labelling of quercetin 4 '-O-beta-D-glucoside. Tetrahedron, 56(24), pp. 4101-4106. (doi: 10.1016/s0040-4020(00)00325-2)

Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462 (2000) Novel methods for the synthesis of three-, four-, five-, six- and seven-membered, saturated and partially unsaturated carbocycles. Journal of the Chemical Society: Perkin Transactions 1, 1(4), pp. 477-501. (doi: 10.1039/A804421J)

This list was generated on Sun Jun 15 14:51:21 2025 BST.
Jump to: Articles
Number of items: 45.

Articles

Eaglesfield, Ross, Fernandez-Vizarra, Erika, Lacko, Erik, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Sloan, Nikki L., Siciarz, Daniel, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Tokatlidis, Kostas ORCID logoORCID: https://orcid.org/0000-0001-6295-8183 (2025) Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter. Redox Biology, 80, 103502. (doi: 10.1016/j.redox.2025.103502) (PMID:39864323) (PMCID:PMC11802384)

Uno, Shinpei, Harkiss, Alexander H., Chowdhury, Roy, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Prime, Tracy A., James, Andrew M., Gallagher, Brendan, Prudent, Julien, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Murphy, Michael P. (2023) Incorporating a polyethyleneglycol linker to enhance the hydrophilicity of mitochondria‐targeted triphenylphosphonium constructs. ChemBioChem, 24(11), e202200774. (doi: 10.1002/cbic.202200774) (PMID:36917207) (PMCID:PMC10946768)

Miljkovic, J. L. et al. (2022) Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury. Redox Biology, 55, 102429. (doi: 10.1016/j.redox.2022.102429) (PMID:35961099) (PMCID:PMC9382561)

Prag, H. A. et al. (2022) Ester prodrugs of malonate with enhanced intracellular delivery protect against cardiac ischemia-reperfusion injury in vivo. Cardiovascular Drugs and Therapy, 36(1), pp. 1-13. (doi: 10.1007/s10557-020-07033-6) (PMID:32648168) (PMCID:PMC8770414)

Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, O'Byrne, Sean, Wilson, Calum, Cvetko, Filip, Murphy, Michael P., McCarron, John G. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2021) Photoactivated release of membrane impermeant sulfonates inside cells. Chemical Communications, 57(32), pp. 3917-3920. (doi: 10.1039/D0CC07713E) (PMID:33871501) (PMCID:PMC7611313)

Gaddale Devanna, K. K. et al. (2021) Tetra-arylborate lipophilic anions as targeting groups. Chemical Communications, 57(25), pp. 3147-3150. (doi: 10.1039/D0CC07924C) (PMID:33634803) (PMCID:PMC8062962)

Cvetko, Filip, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Higgins, Maureen, Suzuki, Takafumi, Yamamoto, Masayuki, Prag, Hiran A., Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405, Dinkova-Kostova, Albena and Murphy, Michael P. (2021) Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. Journal of Biological Chemistry, 296, 100169. (doi: 10.1074/jbc.RA120.016551) (PMID:33298526) (PMCID:PMC7948991)

Tan, S. M. et al. (2021) Targeting methylglyoxal in diabetic kidney disease using the mitochondria-targeted compound MitoGamide. Nutrients, 13(5), 1457. (doi: 10.3390/nu13051457) (PMID:33922959) (PMCID:PMC8145135)

Park, M. et al. (2020) Confirmation of the cardioprotective effect of MitoGamide in the diabetic heart. Cardiovascular Drugs and Therapy, 34, pp. 823-834. (doi: 10.1007/s10557-020-07086-7) (PMID:32979176)

Pala, Laura, Senn, Hans M. ORCID logoORCID: https://orcid.org/0000-0001-8232-5957, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Prime, Tracey A., Warrington, Stefan, Bright, Thomas P., Prag, Hiran A., Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374, Murphy, Michael and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2020) Enhancing the mitochondrial uptake of phosphonium cations by carboxylic acid incorporation. Frontiers in Chemistry, 8, 783. (doi: 10.3389/fchem.2020.00783)

Prag, Hiran A., Kula-Alwar, Duvaraka, Pala, Laura, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Beach, Timothy E., James, Andrew M., Saeb-Parsy, Kourosh, Krieg, Thomas, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Murphy, Michael P. (2020) Selective delivery of dicarboxylates to mitochondria by conjugation to a lipophilic cation via a cleavable linker. Molecular Pharmaceutics, 17(9), pp. 3526-3540. (doi: 10.1021/acs.molpharmaceut.0c00533) (PMID:32692564) (PMCID:PMC7482397)

Burger, Nils, Logan, Angela, Prime, Tracy A., Mottahedin, Amin, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Krieg, Thomas, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405, James, Andrew M. and Murphy, Michael P. (2020) A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo. Free Radical Biology and Medicine, 147, pp. 37-47. (doi: 10.1016/j.freeradbiomed.2019.11.028) (PMID:31811922) (PMCID:PMC6975167)

Tate, M. et al. (2019) The mitochondria-targeted methylglyoxal sequestering compound, MitoGamide, is cardioprotective in the diabetic heart. Cardiovascular Drugs and Therapy, 33(6), pp. 669-674. (doi: 10.1007/s10557-019-06914-9) (PMID:31654171) (PMCID:PMC6994445)

Martin, J. et al. (2019) Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nature Metabolism, 1(10), pp. 966-974. (doi: 10.1038/s42255-019-0115-y)

Antonucci, S. et al. (2019) Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. Free Radical Biology and Medicine, 134, pp. 678-687. (doi: 10.1016/j.freeradbiomed.2019.01.034) (PMID:30731114)

Booty, L. M. et al. (2019) Selective disruption of mitochondrial thiol redox state in cells and in vivo. Cell Chemical Biology, 26(3), 449-461.e8. (doi: 10.1016/j.chembiol.2018.12.002) (PMID:30713096) (PMCID:PMC6436940)

Fazakerley, D. J. et al. (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. Journal of Biological Chemistry, 293(19), pp. 7315-7328. (doi: 10.1074/jbc.RA117.001254) (PMID:29599292) (PMCID:PMC5950018)

Mills, E. L. et al. (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature, 5556, pp. 113-117. (doi: 10.1038/nature25986) (PMID:29590092) (PMCID:PMC6047741)

Cao, Zhenbo, Mitchell, Lorna, Hsia, Oliver, Scarpa, Miriam, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Alfred, Arina D., Gennaris, Alexandra, Collet, Jean-Francois, Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Bulleid, Neil J. ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2018) Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase. Biochemical Journal, 475, pp. 827-838. (doi: 10.1042/BCJ20170929) (PMID:29420254) (PMCID:PMC6488974)

Shchepinova, M. M. et al. (2017) MitoNeoD: a mitochondria-targeted superoxide probe. Cell Chemical Biology, 24(10), 1285-1298.e12. (doi: 10.1016/j.chembiol.2017.08.003) (PMID:28890317) (PMCID:PMC6278870)

Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cairns, Andrew G., Olson, Marnie, Chalmers, Susan, Sandison, Mairi, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, McCarron, John G. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2015) Synthesis of an azido-tagged low affinity ratiometric calcium sensor. Tetrahedron, 71(51), pp. 9571-9578. (doi: 10.1016/j.tet.2015.10.052) (PMID:26709317) (PMCID:PMC4660056)

Caldwell, S.T. et al. (2014) Protein-mediated dethreading of a biotin-functionalised pseudorotaxane. Organic and Biomolecular Chemistry, 12(3), pp. 511-516. (doi: 10.1039/C3OB41612G) (PMID:24280954)

Anamimoghadam, Ommid, Symes, Mark D. ORCID logoORCID: https://orcid.org/0000-0001-8067-5240, Busche, Christoph ORCID logoORCID: https://orcid.org/0000-0002-3493-2020, Long, De-Liang ORCID logoORCID: https://orcid.org/0000-0003-3241-2379, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Flors, Cristina, Nonell, Santi, Cronin, Leroy ORCID logoORCID: https://orcid.org/0000-0001-8035-5757 and Bucher, Goetz ORCID logoORCID: https://orcid.org/0000-0002-5478-8265 (2013) Naphthoxanthenyl, a new stable phenalenyl type radical stabilized by electronic effects. Organic Letters, 15(12), pp. 2970-2973. (doi: 10.1021/ol401117g)

McQuaker, Stephen J., Quinlan, Casey L., Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Brand, Martin D. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2013) A prototypical small-molecule modulator uncouples mitochondria in response to endogenous hydrogen peroxide production. ChemBioChem, 14(8), pp. 993-1000. (doi: 10.1002/cbic.201300115) (PMID:23640856) (PMCID:PMC3743171)

Pauszek, Raymond F., Kodali, Goutham, Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Fitzpatrick, Brian, Zainalabdeen, Nada Y., Cooke, Graeme ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Rotello, Vincent M. and Stanley, Robert J. (2013) Excited state charge redistribution and dynamics in the donor-π-acceptor flavin derivative ABFL. Journal of Physical Chemistry B, 117(49), pp. 15684-15694. (doi: 10.1021/jp406420h)

Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, McPhail, D.B., Duthie, G.D. and Hartley, R.C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2012) Synthesis of polyhydroxylated flavonoids bearing a lipophilic decyl tail as potential therapeutic antioxidants. Canadian Journal of Chemistry = Journal canadien de chimie, 90(1), pp. 23-33. (doi: 10.1139/V11-087)

Chalmers, Susan, Caldwell, Stuart T ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Quin, Caroline, Prime, Tracy A., James, Andrew M., Cairns, Andrew G., Murphy, Michael P, McCarron, John G. and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2012) Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. Journal of the American Chemical Society, 134(2), pp. 758-761. (doi: 10.1021/ja2077922) (PMID:22239373) (PMCID:PMC3260739)

Omar, M.H., Mullen, W. ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Stalmach, A. ORCID logoORCID: https://orcid.org/0000-0003-4491-654X, Auger, C., Rouanet, J.-M., Teissedre, P.-L., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Hartley, R.C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Crozier, A. (2012) Absorption, disposition, metabolism, and excretion of [3-14C]caffeic acid in rats. Journal of Agricultural and Food Chemistry, 60(20), pp. 5205-5214. (doi: 10.1021/jf3001185)

McDonald, N.A., Subramani, C., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Zainalabdeen, N.Y., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Rotello, V.M. (2011) Simultaneous hydrogen bonding and π-stacking interactions between flavin/porphyrin host–guest syst. Tetrahedron Letters, 52(17), pp. 2107-2110. (doi: 10.1016/j.tetlet.2010.11.004)

Figlus, M., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Walas, D., Yesilbag, G., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Kocovsky, P., Malkov, A.V. and Sanyal, A. (2010) Dendron-anchored organocatalysts: the asymmetric reduction of imines with trichlorosilane, catalysed by an amino acid-derived formamide appended to a dendron. Organic and Biomolecular Chemistry, 8(1), pp. 137-141. (doi: 10.1039/b916601g)

Siddle, J. S., Batsanov, A. S., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Bryce, M. R. (2010) Divergent synthesis of arylated pyridin-2(1H)-one derivatives via metal-catalysed cross-coupling processes. Tetrahedron, 66(32), pp. 6138-6149. (doi: 10.1016/j.tet.2010.05.108)

Spreull, J.M. et al. (2010) Highly stable tetrathiafulvalene radical dimers in [3]catenanes. Nature Chemistry, 2(10), pp. 870-879. (doi: 10.1038/nchem.749)

Bigot, J. et al. (2009) LCST: a powerful tool to control complexation between a dialkoxynaphthalene-functionalised poly(N-isopropylacrylamide) and CBPQT(4+) in water. Chemical Communications(35), pp. 5266-5268. (doi: 10.1039/b910856d)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Farrugia, L. J., Hewage, S. G., Kryvokhyzha, N., Rotello, V. M. and Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 (2009) Model systems for flavoenzyme activity: an investigation of the role functionality attached to the C(7) position of the flavin unit has on redox and molecular recognition properties. Chemical Communications(11), pp. 1350-1352. (doi: 10.1039/b900269n)

Malkov, A. V., Figlus, M., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Rabani, G., Prestly, M. R. and Kocovsky, P. (2009) Organocatalysts immobilised onto gold nanoparticles: application in the asymmetric reduction of imines with trichlorosilane. Organic and Biomolecular Chemistry, 7(9), pp. 1878-1883. (doi: 10.1039/b821391g)

Patra, D., Pagliuca, C., Subramani, C., Samanta, B., Agasti, S. S., Zainalabdeen, N., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Rotello, V. M. (2009) Molecular recognition at the liquid-liquid interface of colloidal microcapsules. Chemical Communications(28), pp. 4248-4250. (doi: 10.1039/b906458c)

Jordan, B.J. et al. (2008) 'Lock and key' control of optical properties in a push-pull system. Chemical Communications(14), pp. 1653-1655. (doi: 10.1039/b718015b)

Agasti, S. S., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Jordan, B. J., Kennedy, A., Kryvokhyzha, N., Rabani, G., Rana, S., Sanyal, A. and Rotello, V. M. (2008) Dendron-based model systems for flavoenzyme activity: towards a new class of synthetic flavoenzyme. Chemical Communications(35), pp. 4123-4125. (doi: 10.1039/b809568j)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Cooper, A., Nutley, M., Rabani, G., Rotello, V., Smith, B. O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168 and Woisel, P. (2008) Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT(4+). Chemical Communications(23), pp. 2650-2652. (doi: 10.1039/b803856b)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Fitzpatrick, B., Long, D.L. ORCID logoORCID: https://orcid.org/0000-0003-3241-2379, Rabani, G. and Rotello, V. M. (2008) A flavin-based [2]catenane. Chemical Communications(45), pp. 5912-5914. (doi: 10.1039/b813779j)

Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720, Hewage, S. G., Mabruk, S., Rabani, G., Rotello, V., Smith, B.O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168, Subramani, C. and Woisel, P. (2008) Model systems for flavoenzyme activity: intramolecular self-assembly of a flavin derivative via hydrogen bonding and aromatic interactions. Chemical Communications(35), pp. 4126-4128. (doi: 10.1039/b809762c)

Jordan, B. J., Ofir, Y., Patra, D., Caldwell, S. T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Kennedy, A., Joubanian, S., Rabani, G., Cooke, G. ORCID logoORCID: https://orcid.org/0000-0003-0890-5720 and Rotello, V. M. (2008) Controlled Self-Assembly of Organic Nanowires and Platelets Using Dipolar and Hydrogen-Bonding Interactions. Small, 4(11), pp. 2074-2078. (doi: 10.1002/smll.200800811)

Mullen, W. ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Rouanet, J.-M., Auger, C., Teissèdre, P.-L., Caldwell, S.T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Hartley, R.C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405, Lean, M.E.J. ORCID logoORCID: https://orcid.org/0000-0003-2216-0083, Edwards, C.A. ORCID logoORCID: https://orcid.org/0000-0003-0406-918X and Crozier, A. (2008) Bioavailability of [2-14C]Quercetin-4′-glucoside in rats. Journal of Agricultural and Food Chemistry, 56(24), pp. 12127-12137. (doi: 10.1021/jf802754s)

Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462, Crozier, Alan and Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 (2000) Isotopic labelling of quercetin 4 '-O-beta-D-glucoside. Tetrahedron, 56(24), pp. 4101-4106. (doi: 10.1016/s0040-4020(00)00325-2)

Hartley, Richard C. ORCID logoORCID: https://orcid.org/0000-0003-1033-5405 and Caldwell, Stuart T. ORCID logoORCID: https://orcid.org/0000-0003-1604-3462 (2000) Novel methods for the synthesis of three-, four-, five-, six- and seven-membered, saturated and partially unsaturated carbocycles. Journal of the Chemical Society: Perkin Transactions 1, 1(4), pp. 477-501. (doi: 10.1039/A804421J)

This list was generated on Sun Jun 15 14:51:21 2025 BST.

Research datasets

Jump to: 2025 | 2023 | 2022 | 2020 | 2019 | 2018
Number of items: 9.

2025

Caldwell, S. T. , Sloan, N. L. and Hartley, R. C. (2025) Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter. [Data Collection]

2023

Uno, S., Harkiss, A., Chowdhury, R., Caldwell, S. , Prime, T. A., James, A. M., Gallagher, B., Prudent, J., Hartley, R. and Murphy, M. (2023) Incorporating a Polyethyleneglycol Linker to Enhance the Hydrophilicity of Mitochondria-Targeted Triphenylphosphonium Constructs. [Data Collection]

2022

Miljkovic, J. L., Burger, N., Gawel, J. M., Mulvey, J. F., Norman, A. A. I., Nishimura, T., Tsujihata, Y., Logan, A., Sauchanka, O., Caldwell, S. , Morris, J. L., Prudent, J., Prime, T. A., Warrington, S., Bates, G. R., Aksentijević, D., Prag, H., James, A. M., Krieg, T., Hartley, R. and Murphy, M. (2022) Rapid and Selective Generation of H2S within Mitochondria Protects Against Cardiac Ischemia-Reperfusion Injury. [Data Collection]

2020

Pala, L., Senn, H. , Caldwell, S. , Prime, T. A., Warrington, S., Bright, T. P., Prag, H., Wilson, C. , Murphy, M. and Hartley, R. (2020) Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation. [Data Collection]

Prag, H. A., Kula-Alwar, D., Pala, L., Caldwell, S. , Beach, T., James, A. M., Saeb-Parsy, K., Krieg, T., Hartley, R. and Murphy, M. (2020) Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker. [Data Collection]

2019

Burger, N., Logan, A., Prime, T. A., Mottahedin, A., Caldwell, S. , Krieg, T., Hartley, R. , James, A. M. and Murphy, M. P. (2019) A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo. [Data Collection]

Antonucci, S., Mulvey, J. F., Burger, N., Di Sante, M., Hall, A. R., Hinchy, E. C., Caldwell, S. , Gruszczyk, A. V., Deshwal, S., Hartley, R. , Kaludercic, N., Murphy, M. P., Di Lisa, F. and Kreig, T. (2019) Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. [Data Collection]

2018

Tate, M., De Blasio, M. J., Prakoso, D., Deo, M., Higgins, G. C., Lindblom, R., Kiriazis, H., Baeza-Garza, C. D., Caldwell, S., Hartley, R. , Krieg, T., Murphy, M. P., Coughlan, M. T. and Ritchie, R. H. (2018) The mitochondria-targeted methylglyoxal sequestering compound, MitoGamide is cardioprotective in the diabetic heart. [Data Collection] (Unpublished)

Martin, J. L., Costa, A. S. H., Gruszczyk, A., Beach, T., Allen, F., Prag, H., Hinchy, E. C., Mahbubani, K., Hamed, M., Tronci, L., Nikitopoulou, E., James, A. M., Krieg, T., Robinson, A., Huang, M. H., Caldwell, S. , Logan, A., Pala, L., Hartley, R. , Frezza, C., Saeb-Parsy, K. and Murphy, M. (2018) Succinate accumulation during organ storage drives ischemia-reperfusion injury upon transplantation. [Data Collection]

This list was generated on Sun Jun 15 23:59:01 2025 BST.

Stuart Caldwell square photo