Professor Stephen Clark

  • Chair in Organic Chemistry (School of Chemistry)

telephone: 01413306296
email: Stephen.Clark@glasgow.ac.uk

C4-04 Level C4, Chemistry, Joseph Black Building, Glasgow G12 8QQ

Import to contacts

ORCID iDhttps://orcid.org/0000-0003-3935-0377

Research interests

Research Interests

Synthetic organic chemistry and the development of new synthetic methodology and total synthesis of natural products. More details are available on the website of the Clark research group.

Research Topics

  • Total synthesis of complex bioactive natural product targets
  • Use of metal carbenoids in organic synthesis
  • Applications of ring-closing metathesis reactions in synthesis
  • Asymmetric oxidation and amination reactions
  • Biomimetic synthesis of alkaloids

Publication Highlights

  •  “Rapid Two-directional Synthesis of the F–J Fragment of the Gambieric Acids by Iterative Double Ring-Closing Metathesis” Clark, J. S.; Kimber, M. C.; Robertson J.; McErlean, C. S. P; Wilson, C. Angewandte Chemie, International Edition in English 2005, 44, 6157–6162.
  • “A Concise Total Synthesis of (±)-Vigulariol” Clark, J. S.; Hayes, S. T.; Wilson, C.; Gobbi, L. Angewandte Chemie, International Edition in English 2007, 46, 437–440.
  • “Synthesis of the Fused Polyether Core of Hemibrevetoxin B by Two-directional Ring-closing Metathesis” Clark, J. S.; Grainger, D. M.; Ehkirch, A. A.-C.; Blake, A. J.; Wilson, C. Organic Letters 2007, 9, 1033–1036.
  • “Rapid Synthesis of the A–E Fragment of Ciguatoxin CTX3C” Clark, J. S.; Conroy, J.; Blake, A. J. Organic Letters 2007, 9, 2091–2094.
  • “Stereoselective Construction of the Tricyclic Core of Neoliacinic Acid” Clark, J. S.; Baxter C. A.; Dossetter, A. G.; Poigny, S.; Castro, J. L.; Whittingham, W. G. Journal of Organic Chemistry 2008, 73, 1040–1055.
  • “Enantioselective Total Syntheses of Three Cladiellins (Eunicellins): A General Approach to the Entire Family of Natural Products” Clark, J. S.; Berger, R.; Hayes, S. T.; Thomas, L. H.; Morrison, A. J.; Gobbi L. Angewandte Chemie, International Edition in English 2010, 49, 9867–9870.
  • “Synthesis of the Tricyclic Core of Labiatin A and Australin A” Clark, J. S.; Vignard, D.; Parkin, A. Organic Letters 2011, 13, 3980–3983.

Clark group  

Research groups

Publications

List by: Type | Date

Jump to: 2024 | 2023 | 2022 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001
Number of items: 63.

2024

Chintalapudi, Venkaiah, Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2024) Synthesis of the I-K fused polyether array of CTX3C and related ciguatoxins by use of a gold-catalyzed cyclization reaction. Organic Letters, 26(4), pp. 769-976. (doi: 10.1021/acs.orglett.3c03782) (PMID:38238251) (PMCID:PMC10845158)

2023

Triantafyllakis, Myron, Alexander, Sam, Woolford, Sophie, Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2023) Synthesis of the A−F fragment of the Pacific ciguatoxin CTX3C by iterative ring-closing metathesis and Tsuji–Trost allylation. Chemistry: A European Journal, 27(72), e202303121. (doi: 10.1002/chem.202303121) (PMID:37830907)

2022

Romiti, Filippo, Decultot, Ludovic and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2022) Convergent synthesis of the C1-C29 framework of amphidinolide F. Journal of Organic Chemistry, 87(12), pp. 8126-8141. (doi: 10.1021/acs.joc.2c00850) (PMID:35675580) (PMCID:PMC9207912)

Neckebroeck, Albane, Kelly, Sharon M. ORCID logoORCID: https://orcid.org/0000-0002-3516-1387, Smith, Brian O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2022) Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability. Journal of Organic Chemistry, 87(1), pp. 258-270. (doi: 10.1021/acs.joc.1c02344) (PMID:34913698)

Decultot, Ludovic and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2022) Synthetic studies on amphidinolide F: exploration of macrocycle construction by intramolecular Stille coupling. Organic Letters, 24(41), pp. 7600-7604. (doi: 10.1021/acs.orglett.2c03045) (PMID:36223230)

2020

J. Clark, Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Popadynec, Michael (2020) Stereoselective synthesis of the I–L fragment of the Pacific ciguatoxins. Toxins, 12(12), 740. (doi: 10.3390/toxins12120740) (PMID:33255410) (PMCID:PMC7760828)

Crecente Garcia, Selma, Neckebroeck, Albane, Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Smith, Brian O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168 and Thomson, Andrew R. ORCID logoORCID: https://orcid.org/0000-0002-1066-1369 (2020) β-turn mimics by chemical ligation. Organic Letters, 22(11), pp. 4424-4428. (doi: 10.1021/acs.orglett.0c01427) (PMID:32406695) (PMCID:PMC7304061)

Popadynec, Michael, Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Gibbard, Helen (2020) Bidirectional synthesis of the IJK fragment of ciguatoxin CTX3C by sequential double ring-closing metathesis and Tsuji-Trost allylation. Organic Letters, 22(9), pp. 3734-3738. (doi: 10.1021/acs.orglett.0c01238) (PMID:32306737) (PMCID:PMC7304930)

Campbell, Angus, Mat Som, Ian, Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2020) Total syntheses of 11-acetoxy-4-deoxyasbestinin D, 4-deoxyasbestinin C, asbestinin-10, -20, -21 and -23. Chemistry: A European Journal, 26(5), pp. 1155-1160. (doi: 10.1002/chem.201904998) (PMID:31710141)

2019

Elustondo, Frédéric, Chintalapudi, Venkaiah and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2019) A short sequence for the iterative synthesis of fused polyethers. Helvetica Chimica Acta, 102(9), e1900161. (doi: 10.1002/hlca.201900161)

Aimon, Anthony, Farrugia, Louis J. and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2019) Synthesis of the core framework of the cornexistins by intramolecular Nozaki-Hiyama-Kishi coupling. Molecules, 24(14), 2654. (doi: 10.3390/molecules24142654) (PMID:31336669) (PMCID:PMC6680490)

Qin, Shuanglin, Cao, Yuting, Luo, Yunhao, Jiang, Shende, Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Wang, Xiaoji and Yang, Guang (2019) Multi‐gram scale synthesis of chiral 3‐methyl‐2,5‐trans‐tetrahydrofurans. Helvetica Chimica Acta, 102(7), e1900131. (doi: 10.1002/hlca.201900131)

2018

Klaus, Verena, Wittmann, Stéphane, Senn, Hans M. ORCID logoORCID: https://orcid.org/0000-0001-8232-5957 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2018) Synthesis of fused tricyclic systems by thermal cope rearrangement of furan-substituted vinyl cyclopropanes. Organic and Biomolecular Chemistry, 16(21), pp. 3970-3982. (doi: 10.1039/C8OB00924D) (PMID:29761822)

Skardon-Duncan, James, Sparenberg, Michael, Bayle, Alexandre, Alexander, Sam and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2018) Stereoselective synthesis of medium-sized cyclic ethers by sequential ring-closing metathesis and Tsuji–Trost allylation. Organic Letters, 20(9), pp. 2782-2786. (doi: 10.1021/acs.orglett.8b01082) (PMID:29676923)

2017

Mcaulay, Kirsten and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2017) Total synthesis of 7-epi-pukalide and 7-acetylsinumaximol B. Chemistry: A European Journal, 23(41), pp. 9761-9765. (doi: 10.1002/chem.201702591)

Xu, Chao, Wittmann, Stéphane, Gemander, Manuel, Ruohonen, Venla and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2017) Trialkylphosphine-mediated synthesis of 2-Acyl furans from ynenones. Organic Letters, 19(13), pp. 3556-3559. (doi: 10.1021/acs.orglett.7b01533) (PMID:28654294)

Klaus, Verena and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2017) Thioether-catalysed tandem synthesis of furans and cyclic ethers or lactones. Synlett, 28(11), pp. 1358-1362. (doi: 10.1055/s-0036-1588758)

2016

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Xu, Chao (2016) Total synthesis of (–)-nakadomarin A. Angewandte Chemie (International Edition), 55(13), pp. 4332-4335. (doi: 10.1002/anie.201600990)

2015

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Romiti, Filippo, Sieng, Bora, Paterson, Laura C., Stewart, Alister, Chaudhury, Subhabrata and Thomas, Lynne H. (2015) Synthesis of the A–D ring system of the gambieric acids. Organic Letters, 17(19), pp. 4694-4697. (doi: 10.1021/acs.orglett.5b02093)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Romiti, Filippo, Hogg, Kirsten F., Hamid, Malai Haniti S. A., Richter, Sven C., Boyer, Alistair ORCID logoORCID: https://orcid.org/0000-0002-8415-4204, Redman, Joanna C. and Farrugia, Louis J. (2015) Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions. Angewandte Chemie (International Edition), 54(19), pp. 5744-5747. (doi: 10.1002/anie.201500625) (PMID:25782604)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Delion, Laëtitia and Farrugia, Louis J. (2015) Synthesis of four diastereomers of sclerophytin f and structural reassignment of several sclerophytin natural products. Chemistry: A European Journal, 21(12), pp. 4772-4780. (doi: 10.1002/chem.201406051) (PMID:25663662)

2014

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Delion, Laetitia and Farrugia, Louis J. (2014) Total synthesis of the purported structure of sclerophytin F. Organic Letters, 16(16), pp. 4300-4303. (doi: 10.1021/ol5020152)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Hansen, K. Emelie (2014) Intramolecular reactions of metal carbenoids with allylic ethers: is a free ylide involved in every case? Chemistry: A European Journal, 20(18), pp. 5454-5459. (doi: 10.1002/chem.201304054) (PMID:24648216)

2013

Clark, S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Guang, Y. and Osnowski, A. (2013) Synthesis of the C‑18-C-34 fragment of amphidinolides C, C2, and C3. Organic Letters, 15(7), pp. 1464-1467. (doi: 10.1021/ol400482j)

Clark, Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Yang, G. and Osnowski, A. (2013) Synthesis of the C‑1-C-17 fragment of amphidinolides C, C2, C3, and F. Organic Letters, 15(7), pp. 1460-1463. (doi: 10.1021/ol4004838)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Berger, R., Hayes, S.T., Senn, H.M. ORCID logoORCID: https://orcid.org/0000-0001-8232-5957, Farrugia, L.J., Thomas, L.H., Morrison, A.J. and Gobbi, L. (2013) Total syntheses of multiple cladiellin natural products by use of a completely general strategy. Journal of Organic Chemistry, 78(2), pp. 673-696. (doi: 10.1021/jo302542h)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Romiti, F. (2013) Total syntheses of amphidinolides T1, T3, and T4. Angewandte Chemie (International Edition), 52(38), pp. 10072-10075. (doi: 10.1002/anie.201305467)

2012

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Boyer, A. ORCID logoORCID: https://orcid.org/0000-0002-8415-4204, Aimon, A., Garcia, P.E., Lindsay, D.M., Symington, A.D.F. and Danoy, Y. (2012) Organocatalytic synthesis of highly substituted furfuryl alcohols and amines. Angewandte Chemie (International Edition), 51(48), pp. 12128-12131. (doi: 10.1002/anie.201207300)

2011

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Labre, F. and Thomas, L.H. (2011) Concise synthesis of the C-1–C-12 fragment of amphidinolides T1–T5. Organic and Biomolecular Chemistry, 9, pp. 4823-4830. (doi: 10.1039/c1ob05130j)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Vignard, D. and Parkin, A. (2011) Synthesis of the tricyclic core of labiatin A and australin A. Organic Letters, 13(15), pp. 3980-3983. (doi: 10.1021/ol201498g)

2010

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Berger, R., Hayes, S.T., Thomas, L.H., Morrison, A.J. and Gobbi, L. (2010) Enantioselective total syntheses of three cladiellins (eunicellins): a general approach to the entire family of natural products. Angewandte Chemie (International Edition), 49(51), pp. 9867-9870. (doi: 10.1002/anie.201005508)

2008

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Baxter, C.A., Dossetter, A.G., Poigny, S., Castro, J.L. and Whittingham, W.G. (2008) Stereoselective construction of the tricyclic core of neoliacinic acid. Journal of Organic Chemistry, 73(3), pp. 1040-1055. (doi: 10.1021/jo702111u)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Northall, J.M., Marlin, F., Nay, B., Wilson, C., Blake, A.J. and Waring, M.J. (2008) Synthetic studies on the cornexistins: synthesis of (+/-)-5-epi-hydroxycornexistin. Organic and Biomolecular Chemistry, 6(21), pp. 4012-4025. (doi: 10.1039/b811245b)

2007

Clark, J. Stephen, Hayes, Stewart T., Wilson, Claire and Gobbi, Luca (2007) A concise total synthesis of (+/-)-vigulariol. Angewandte Chemie (International Edition), 46(3), pp. 437-440. (doi: 10.1002/anie.200603880)

Clark, JS, Grainger, DM, Ehkirch, AAC, Blake, AJ and Wilson, C (2007) Synthesis of the fused polyether core of hemibrevetoxin B by two-directional ring-closing metathesis. Organic Letters, 9, pp. 1033-1036. (doi: 10.1021/ol0630651)

Clark, JS, Guerot, C, Wilson, C and Blake, AJ (2007) Rapid synthesis of medium-ring fused polycarbocyclic systems by rearrangement of carbenoid-derived oxonium ylides. Chemical Communications, pp. 4134-4136. (doi: 10.1039/b709064a)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Conroy, J and Blake, AJ (2007) Rapid synthesis of the A-E fragment of ciguatoxin CTX3C. Organic Letters, 9, pp. 2091-2094. (doi: 10.1021/ol0706096)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Hayes, ST, Blake, AJ and Gobbi, L (2007) Synthesis of a lactone natural product found in Greek tobacco. Tetrahedron Letters, 48, pp. 2501-2503. (doi: 10.1016/j.tetlet.2007.02.039)

2006

Clark, JS, Walls, SB, Wilson, C, East, SP and Drysdale, MJ (2006) Construction of fused medium-ring carbocycles by catalytic generation and rearrangement of oxonium ylides. European Journal of Organic Chemistry, pp. 323-327. (doi: 10.1002/ejoc.200500830)

Clark, JS, Winfield, LJ, Wilson, C and Blake, AJ (2006) Synthetic studies on the cladiellins (eunicellins): Unexpected selenoxide displacement with concomitant alcohol oxidation during attempted selenoxide elimination. Synlett, pp. 2191-2194. (doi: 10.1055/s-2006-949611)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2006) Construction of fused polycyclic ethers by strategies involving ring-closing metathesis. Chemical Communications, pp. 3571-3581. (doi: 10.1039/b601839d)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Fessard, TC and Whitlock, GA (2006) A concise enantioselective synthesis of the fungal metabolite (+)-decarestrictine L. Tetrahedron, 62, pp. 73-78. (doi: 10.1016/j.tet.2005.09.144)

2005

Clark, J.Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Baxter, Carl A. and Castro, Jose L. (2005) Synthesis of the tricyclic core of the marine natural product labiatin A. Synthesis(19), pp. 3398-3404. (doi: 10.1055/s-2005-918485)

Clark, JS, Kimber, MC, Robertson, J, McErlean, CSP and Wilson, C (2005) Rapid two-directional synthesis of the F-J fragment of the gambieric acids by iterative double ring-closing metathesis. Angewandte Chemie (International Edition), 44, pp. 6157-6162. (doi: 10.1002/anie.200501925)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Myatt, J, Roberts, L and Walshe, N (2005) Investigation of the biomimetic synthesis of emindole SB using a fluorinated polyene cyclisation precursor. Synlett, pp. 697-699. (doi: 10.1055/s-2005-863721)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Roche, C (2005) Tuneable asymmetric copper-catalysed allylic amination and oxidation reactions. Chemical Communications, pp. 5175-5177. (doi: 10.1039/b509678b)

2004

Clark, JS, Clarke, MR, Clough, J, Blake, AJ and Wilson, C (2004) Asymmetric allyfic oxidation of bridged-bicyclic alkenes using a copper-catalysed symmetrising-desymmetrising Kharasch-Sosnovsky reaction. Tetrahedron Letters, 45, pp. 9447-9450. (doi: 10.1016/j.tetlet.2004.10.093)

Clark, JS, Fessard, TC and Wilson, C (2004) A concise and stereoselective synthesis of the A-ring fragment of the gambieric acids. Organic Letters, 6, pp. 1773-1776. (doi: 10.1021/ol049483s)

Clark, JS, Freeman, RP, Cacho, M, Thomas, AW, Swallow, S and Wilson, C (2004) Stereoselective synthesis of the cyclic ether core of (+)-laurenyne. Tetrahedron Letters, 45, pp. 8639-8642. (doi: 10.1016/j.tetlet.2004.09.160)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Dossetter, AG, Wong, YS, Townsend, RJ, Whittingham, WG and Russell, CA (2004) Anomalous intramolecular C-H insertion reactions of rhodium carbenoids: Factors influencing the reaction course and mechanistic implications. Journal of Organic Chemistry, 69, pp. 3886-3898. (doi: 10.1021/jo049900e)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Elustondo, F and Kimber, MC (2004) Construction of building-blocks for polyether synthesis using sequential catalytic ring-closing enyne and cross metathesis. Chemical Communications, pp. 2470-2471. (doi: 10.1039/b409067e)

2003

Clark, JS, Marlin, F, Nay, B and Wilson, C (2003) Synthesis of the carbocyclic core of the cornexistins by ring-closing metathesis. Organic Letters, 5, pp. 89-92. (doi: 10.1021/ol027265y)

Clark, JS, Myatt, J, Wilson, C, Roberts, L and Walshe, N (2003) Exploration of the biomimetic synthesis of indole-diterpene mycotoxins: an unexpected cascade reaction during the attempted synthesis of emindole SB. Chemical Communications, pp. 1546-1547. (doi: 10.1039/b302105j)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Middleton, M.D. (2003) Direct peptide coupling of novel amino acid derivatives produced by rearrangement of catalytically generated ammonium ylides. Tetrahedron Letters, 44, pp. 7031-7034. (doi: 10.1016/S0040-4039(03)01778-7)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Whitlock, G, Jiang, S and Onyia, N (2003) Stereoselective synthesis of tetrahydropyran-3-ones by rearrangement of oxonium ylides generated from metal carbenoids. Chemical Communications, pp. 2578-2579. (doi: 10.1039/b307858m)

2002

Cameron, KS, Clark, JK ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Cooper, A, Fielding, L, Palin, R, Rutherford, SJ and Zhang, MQ (2002) Modified gamma-cyclodextrins and their rocuronium complexes. Organic Letters, 4, pp. 3403-3406. (doi: 10.1021/ol020126w)

Clark, JS, Elustondo, F, Trevitt, GP, Boyall, D, Robertson, J, Blake, AJ, Wilson, C and Stammen, B (2002) Preparation of cyclic ethers for polyether synthesis by catalytic ring-closing enyne metathesis of alkynyl ethers. Tetrahedron, 58, pp. 1973-1982.

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Middleton, MD (2002) Synthesis of novel alpha-substituted and alpha,alpha-disubstituted amino acids by rearrangement of ammonium ylides generated from metal carbenoids. Organic Letters, 4, pp. 765-768. (doi: 10.1021/ol017240j)

2001

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Hodgson, P.B., Goldsmith, M.D. and Street, L.J. (2001) Rearrangement of ammonium ylides produced by intramolecular reaction of catalytically generated metal carbenoids. Part 1. Synthesis of cyclic amines. Journal of the Chemical Society: Perkin Transactions 1, pp. 3312-3324. (doi: 10.1039/b108179a)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Bate, AL and Grinter, T (2001) A novel approach to the construction of medium-ring carbocycles utilising the rearrangement of oxonium ylides generated from metal carbenoids. Chemical Communications, pp. 459-460.

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Townsend, RJ, Blake, AJ, Teat, SJ and Johns, A (2001) A concise enantioselective synthesis of the AB ring system of the manzamine alkaloids by ring-closing enyne metathesis. Tetrahedron Letters, 42, pp. 3235-3238.

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Wong, YS and Townsend, RJ (2001) Probing the mechanism of the anomalous intramolecular C-H insertion reaction of rhodium carbenoids by analysis of kinetic isotope effects. Tetrahedron Letters, 42, pp. 6187-6190.

Wilson, C, Clark, JS, Bate, AL, Blake, AJ, Grinter, T and Teat, SJ (2001) Diels-Alder adducts of medium-ring carbocyclic dienes prepared by rearrangement of catalytically generated cyclic oxonium ylides. Acta Crystallographica. Section C: Crystal Structure Communications, 57, pp. 1326-1329.

This list was generated on Wed Jul 2 14:39:39 2025 BST.
Jump to: Articles
Number of items: 63.

Articles

Chintalapudi, Venkaiah, Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2024) Synthesis of the I-K fused polyether array of CTX3C and related ciguatoxins by use of a gold-catalyzed cyclization reaction. Organic Letters, 26(4), pp. 769-976. (doi: 10.1021/acs.orglett.3c03782) (PMID:38238251) (PMCID:PMC10845158)

Triantafyllakis, Myron, Alexander, Sam, Woolford, Sophie, Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2023) Synthesis of the A−F fragment of the Pacific ciguatoxin CTX3C by iterative ring-closing metathesis and Tsuji–Trost allylation. Chemistry: A European Journal, 27(72), e202303121. (doi: 10.1002/chem.202303121) (PMID:37830907)

Romiti, Filippo, Decultot, Ludovic and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2022) Convergent synthesis of the C1-C29 framework of amphidinolide F. Journal of Organic Chemistry, 87(12), pp. 8126-8141. (doi: 10.1021/acs.joc.2c00850) (PMID:35675580) (PMCID:PMC9207912)

Neckebroeck, Albane, Kelly, Sharon M. ORCID logoORCID: https://orcid.org/0000-0002-3516-1387, Smith, Brian O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2022) Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability. Journal of Organic Chemistry, 87(1), pp. 258-270. (doi: 10.1021/acs.joc.1c02344) (PMID:34913698)

Decultot, Ludovic and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2022) Synthetic studies on amphidinolide F: exploration of macrocycle construction by intramolecular Stille coupling. Organic Letters, 24(41), pp. 7600-7604. (doi: 10.1021/acs.orglett.2c03045) (PMID:36223230)

J. Clark, Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Popadynec, Michael (2020) Stereoselective synthesis of the I–L fragment of the Pacific ciguatoxins. Toxins, 12(12), 740. (doi: 10.3390/toxins12120740) (PMID:33255410) (PMCID:PMC7760828)

Crecente Garcia, Selma, Neckebroeck, Albane, Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Smith, Brian O. ORCID logoORCID: https://orcid.org/0000-0003-3363-4168 and Thomson, Andrew R. ORCID logoORCID: https://orcid.org/0000-0002-1066-1369 (2020) β-turn mimics by chemical ligation. Organic Letters, 22(11), pp. 4424-4428. (doi: 10.1021/acs.orglett.0c01427) (PMID:32406695) (PMCID:PMC7304061)

Popadynec, Michael, Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Gibbard, Helen (2020) Bidirectional synthesis of the IJK fragment of ciguatoxin CTX3C by sequential double ring-closing metathesis and Tsuji-Trost allylation. Organic Letters, 22(9), pp. 3734-3738. (doi: 10.1021/acs.orglett.0c01238) (PMID:32306737) (PMCID:PMC7304930)

Campbell, Angus, Mat Som, Ian, Wilson, Claire ORCID logoORCID: https://orcid.org/0000-0002-0090-5374 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2020) Total syntheses of 11-acetoxy-4-deoxyasbestinin D, 4-deoxyasbestinin C, asbestinin-10, -20, -21 and -23. Chemistry: A European Journal, 26(5), pp. 1155-1160. (doi: 10.1002/chem.201904998) (PMID:31710141)

Elustondo, Frédéric, Chintalapudi, Venkaiah and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2019) A short sequence for the iterative synthesis of fused polyethers. Helvetica Chimica Acta, 102(9), e1900161. (doi: 10.1002/hlca.201900161)

Aimon, Anthony, Farrugia, Louis J. and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2019) Synthesis of the core framework of the cornexistins by intramolecular Nozaki-Hiyama-Kishi coupling. Molecules, 24(14), 2654. (doi: 10.3390/molecules24142654) (PMID:31336669) (PMCID:PMC6680490)

Qin, Shuanglin, Cao, Yuting, Luo, Yunhao, Jiang, Shende, Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Wang, Xiaoji and Yang, Guang (2019) Multi‐gram scale synthesis of chiral 3‐methyl‐2,5‐trans‐tetrahydrofurans. Helvetica Chimica Acta, 102(7), e1900131. (doi: 10.1002/hlca.201900131)

Klaus, Verena, Wittmann, Stéphane, Senn, Hans M. ORCID logoORCID: https://orcid.org/0000-0001-8232-5957 and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2018) Synthesis of fused tricyclic systems by thermal cope rearrangement of furan-substituted vinyl cyclopropanes. Organic and Biomolecular Chemistry, 16(21), pp. 3970-3982. (doi: 10.1039/C8OB00924D) (PMID:29761822)

Skardon-Duncan, James, Sparenberg, Michael, Bayle, Alexandre, Alexander, Sam and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2018) Stereoselective synthesis of medium-sized cyclic ethers by sequential ring-closing metathesis and Tsuji–Trost allylation. Organic Letters, 20(9), pp. 2782-2786. (doi: 10.1021/acs.orglett.8b01082) (PMID:29676923)

Mcaulay, Kirsten and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2017) Total synthesis of 7-epi-pukalide and 7-acetylsinumaximol B. Chemistry: A European Journal, 23(41), pp. 9761-9765. (doi: 10.1002/chem.201702591)

Xu, Chao, Wittmann, Stéphane, Gemander, Manuel, Ruohonen, Venla and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2017) Trialkylphosphine-mediated synthesis of 2-Acyl furans from ynenones. Organic Letters, 19(13), pp. 3556-3559. (doi: 10.1021/acs.orglett.7b01533) (PMID:28654294)

Klaus, Verena and Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2017) Thioether-catalysed tandem synthesis of furans and cyclic ethers or lactones. Synlett, 28(11), pp. 1358-1362. (doi: 10.1055/s-0036-1588758)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Xu, Chao (2016) Total synthesis of (–)-nakadomarin A. Angewandte Chemie (International Edition), 55(13), pp. 4332-4335. (doi: 10.1002/anie.201600990)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Romiti, Filippo, Sieng, Bora, Paterson, Laura C., Stewart, Alister, Chaudhury, Subhabrata and Thomas, Lynne H. (2015) Synthesis of the A–D ring system of the gambieric acids. Organic Letters, 17(19), pp. 4694-4697. (doi: 10.1021/acs.orglett.5b02093)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Romiti, Filippo, Hogg, Kirsten F., Hamid, Malai Haniti S. A., Richter, Sven C., Boyer, Alistair ORCID logoORCID: https://orcid.org/0000-0002-8415-4204, Redman, Joanna C. and Farrugia, Louis J. (2015) Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions. Angewandte Chemie (International Edition), 54(19), pp. 5744-5747. (doi: 10.1002/anie.201500625) (PMID:25782604)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Delion, Laëtitia and Farrugia, Louis J. (2015) Synthesis of four diastereomers of sclerophytin f and structural reassignment of several sclerophytin natural products. Chemistry: A European Journal, 21(12), pp. 4772-4780. (doi: 10.1002/chem.201406051) (PMID:25663662)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Delion, Laetitia and Farrugia, Louis J. (2014) Total synthesis of the purported structure of sclerophytin F. Organic Letters, 16(16), pp. 4300-4303. (doi: 10.1021/ol5020152)

Clark, J. Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Hansen, K. Emelie (2014) Intramolecular reactions of metal carbenoids with allylic ethers: is a free ylide involved in every case? Chemistry: A European Journal, 20(18), pp. 5454-5459. (doi: 10.1002/chem.201304054) (PMID:24648216)

Clark, S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Guang, Y. and Osnowski, A. (2013) Synthesis of the C‑18-C-34 fragment of amphidinolides C, C2, and C3. Organic Letters, 15(7), pp. 1464-1467. (doi: 10.1021/ol400482j)

Clark, Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Yang, G. and Osnowski, A. (2013) Synthesis of the C‑1-C-17 fragment of amphidinolides C, C2, C3, and F. Organic Letters, 15(7), pp. 1460-1463. (doi: 10.1021/ol4004838)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Berger, R., Hayes, S.T., Senn, H.M. ORCID logoORCID: https://orcid.org/0000-0001-8232-5957, Farrugia, L.J., Thomas, L.H., Morrison, A.J. and Gobbi, L. (2013) Total syntheses of multiple cladiellin natural products by use of a completely general strategy. Journal of Organic Chemistry, 78(2), pp. 673-696. (doi: 10.1021/jo302542h)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Romiti, F. (2013) Total syntheses of amphidinolides T1, T3, and T4. Angewandte Chemie (International Edition), 52(38), pp. 10072-10075. (doi: 10.1002/anie.201305467)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Boyer, A. ORCID logoORCID: https://orcid.org/0000-0002-8415-4204, Aimon, A., Garcia, P.E., Lindsay, D.M., Symington, A.D.F. and Danoy, Y. (2012) Organocatalytic synthesis of highly substituted furfuryl alcohols and amines. Angewandte Chemie (International Edition), 51(48), pp. 12128-12131. (doi: 10.1002/anie.201207300)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Labre, F. and Thomas, L.H. (2011) Concise synthesis of the C-1–C-12 fragment of amphidinolides T1–T5. Organic and Biomolecular Chemistry, 9, pp. 4823-4830. (doi: 10.1039/c1ob05130j)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Vignard, D. and Parkin, A. (2011) Synthesis of the tricyclic core of labiatin A and australin A. Organic Letters, 13(15), pp. 3980-3983. (doi: 10.1021/ol201498g)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Berger, R., Hayes, S.T., Thomas, L.H., Morrison, A.J. and Gobbi, L. (2010) Enantioselective total syntheses of three cladiellins (eunicellins): a general approach to the entire family of natural products. Angewandte Chemie (International Edition), 49(51), pp. 9867-9870. (doi: 10.1002/anie.201005508)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Baxter, C.A., Dossetter, A.G., Poigny, S., Castro, J.L. and Whittingham, W.G. (2008) Stereoselective construction of the tricyclic core of neoliacinic acid. Journal of Organic Chemistry, 73(3), pp. 1040-1055. (doi: 10.1021/jo702111u)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Northall, J.M., Marlin, F., Nay, B., Wilson, C., Blake, A.J. and Waring, M.J. (2008) Synthetic studies on the cornexistins: synthesis of (+/-)-5-epi-hydroxycornexistin. Organic and Biomolecular Chemistry, 6(21), pp. 4012-4025. (doi: 10.1039/b811245b)

Clark, J. Stephen, Hayes, Stewart T., Wilson, Claire and Gobbi, Luca (2007) A concise total synthesis of (+/-)-vigulariol. Angewandte Chemie (International Edition), 46(3), pp. 437-440. (doi: 10.1002/anie.200603880)

Clark, JS, Grainger, DM, Ehkirch, AAC, Blake, AJ and Wilson, C (2007) Synthesis of the fused polyether core of hemibrevetoxin B by two-directional ring-closing metathesis. Organic Letters, 9, pp. 1033-1036. (doi: 10.1021/ol0630651)

Clark, JS, Guerot, C, Wilson, C and Blake, AJ (2007) Rapid synthesis of medium-ring fused polycarbocyclic systems by rearrangement of carbenoid-derived oxonium ylides. Chemical Communications, pp. 4134-4136. (doi: 10.1039/b709064a)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Conroy, J and Blake, AJ (2007) Rapid synthesis of the A-E fragment of ciguatoxin CTX3C. Organic Letters, 9, pp. 2091-2094. (doi: 10.1021/ol0706096)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Hayes, ST, Blake, AJ and Gobbi, L (2007) Synthesis of a lactone natural product found in Greek tobacco. Tetrahedron Letters, 48, pp. 2501-2503. (doi: 10.1016/j.tetlet.2007.02.039)

Clark, JS, Walls, SB, Wilson, C, East, SP and Drysdale, MJ (2006) Construction of fused medium-ring carbocycles by catalytic generation and rearrangement of oxonium ylides. European Journal of Organic Chemistry, pp. 323-327. (doi: 10.1002/ejoc.200500830)

Clark, JS, Winfield, LJ, Wilson, C and Blake, AJ (2006) Synthetic studies on the cladiellins (eunicellins): Unexpected selenoxide displacement with concomitant alcohol oxidation during attempted selenoxide elimination. Synlett, pp. 2191-2194. (doi: 10.1055/s-2006-949611)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 (2006) Construction of fused polycyclic ethers by strategies involving ring-closing metathesis. Chemical Communications, pp. 3571-3581. (doi: 10.1039/b601839d)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Fessard, TC and Whitlock, GA (2006) A concise enantioselective synthesis of the fungal metabolite (+)-decarestrictine L. Tetrahedron, 62, pp. 73-78. (doi: 10.1016/j.tet.2005.09.144)

Clark, J.Stephen ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Baxter, Carl A. and Castro, Jose L. (2005) Synthesis of the tricyclic core of the marine natural product labiatin A. Synthesis(19), pp. 3398-3404. (doi: 10.1055/s-2005-918485)

Clark, JS, Kimber, MC, Robertson, J, McErlean, CSP and Wilson, C (2005) Rapid two-directional synthesis of the F-J fragment of the gambieric acids by iterative double ring-closing metathesis. Angewandte Chemie (International Edition), 44, pp. 6157-6162. (doi: 10.1002/anie.200501925)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Myatt, J, Roberts, L and Walshe, N (2005) Investigation of the biomimetic synthesis of emindole SB using a fluorinated polyene cyclisation precursor. Synlett, pp. 697-699. (doi: 10.1055/s-2005-863721)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Roche, C (2005) Tuneable asymmetric copper-catalysed allylic amination and oxidation reactions. Chemical Communications, pp. 5175-5177. (doi: 10.1039/b509678b)

Clark, JS, Clarke, MR, Clough, J, Blake, AJ and Wilson, C (2004) Asymmetric allyfic oxidation of bridged-bicyclic alkenes using a copper-catalysed symmetrising-desymmetrising Kharasch-Sosnovsky reaction. Tetrahedron Letters, 45, pp. 9447-9450. (doi: 10.1016/j.tetlet.2004.10.093)

Clark, JS, Fessard, TC and Wilson, C (2004) A concise and stereoselective synthesis of the A-ring fragment of the gambieric acids. Organic Letters, 6, pp. 1773-1776. (doi: 10.1021/ol049483s)

Clark, JS, Freeman, RP, Cacho, M, Thomas, AW, Swallow, S and Wilson, C (2004) Stereoselective synthesis of the cyclic ether core of (+)-laurenyne. Tetrahedron Letters, 45, pp. 8639-8642. (doi: 10.1016/j.tetlet.2004.09.160)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Dossetter, AG, Wong, YS, Townsend, RJ, Whittingham, WG and Russell, CA (2004) Anomalous intramolecular C-H insertion reactions of rhodium carbenoids: Factors influencing the reaction course and mechanistic implications. Journal of Organic Chemistry, 69, pp. 3886-3898. (doi: 10.1021/jo049900e)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Elustondo, F and Kimber, MC (2004) Construction of building-blocks for polyether synthesis using sequential catalytic ring-closing enyne and cross metathesis. Chemical Communications, pp. 2470-2471. (doi: 10.1039/b409067e)

Clark, JS, Marlin, F, Nay, B and Wilson, C (2003) Synthesis of the carbocyclic core of the cornexistins by ring-closing metathesis. Organic Letters, 5, pp. 89-92. (doi: 10.1021/ol027265y)

Clark, JS, Myatt, J, Wilson, C, Roberts, L and Walshe, N (2003) Exploration of the biomimetic synthesis of indole-diterpene mycotoxins: an unexpected cascade reaction during the attempted synthesis of emindole SB. Chemical Communications, pp. 1546-1547. (doi: 10.1039/b302105j)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Middleton, M.D. (2003) Direct peptide coupling of novel amino acid derivatives produced by rearrangement of catalytically generated ammonium ylides. Tetrahedron Letters, 44, pp. 7031-7034. (doi: 10.1016/S0040-4039(03)01778-7)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Whitlock, G, Jiang, S and Onyia, N (2003) Stereoselective synthesis of tetrahydropyran-3-ones by rearrangement of oxonium ylides generated from metal carbenoids. Chemical Communications, pp. 2578-2579. (doi: 10.1039/b307858m)

Cameron, KS, Clark, JK ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Cooper, A, Fielding, L, Palin, R, Rutherford, SJ and Zhang, MQ (2002) Modified gamma-cyclodextrins and their rocuronium complexes. Organic Letters, 4, pp. 3403-3406. (doi: 10.1021/ol020126w)

Clark, JS, Elustondo, F, Trevitt, GP, Boyall, D, Robertson, J, Blake, AJ, Wilson, C and Stammen, B (2002) Preparation of cyclic ethers for polyether synthesis by catalytic ring-closing enyne metathesis of alkynyl ethers. Tetrahedron, 58, pp. 1973-1982.

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377 and Middleton, MD (2002) Synthesis of novel alpha-substituted and alpha,alpha-disubstituted amino acids by rearrangement of ammonium ylides generated from metal carbenoids. Organic Letters, 4, pp. 765-768. (doi: 10.1021/ol017240j)

Clark, J.S. ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Hodgson, P.B., Goldsmith, M.D. and Street, L.J. (2001) Rearrangement of ammonium ylides produced by intramolecular reaction of catalytically generated metal carbenoids. Part 1. Synthesis of cyclic amines. Journal of the Chemical Society: Perkin Transactions 1, pp. 3312-3324. (doi: 10.1039/b108179a)

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Bate, AL and Grinter, T (2001) A novel approach to the construction of medium-ring carbocycles utilising the rearrangement of oxonium ylides generated from metal carbenoids. Chemical Communications, pp. 459-460.

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Townsend, RJ, Blake, AJ, Teat, SJ and Johns, A (2001) A concise enantioselective synthesis of the AB ring system of the manzamine alkaloids by ring-closing enyne metathesis. Tetrahedron Letters, 42, pp. 3235-3238.

Clark, JS ORCID logoORCID: https://orcid.org/0000-0003-3935-0377, Wong, YS and Townsend, RJ (2001) Probing the mechanism of the anomalous intramolecular C-H insertion reaction of rhodium carbenoids by analysis of kinetic isotope effects. Tetrahedron Letters, 42, pp. 6187-6190.

Wilson, C, Clark, JS, Bate, AL, Blake, AJ, Grinter, T and Teat, SJ (2001) Diels-Alder adducts of medium-ring carbocyclic dienes prepared by rearrangement of catalytically generated cyclic oxonium ylides. Acta Crystallographica. Section C: Crystal Structure Communications, 57, pp. 1326-1329.

This list was generated on Wed Jul 2 14:39:39 2025 BST.

Teaching

Teaching

  • Level-3 Organic Synthesis 2 – Retrosynthetic Analysis and Synthesis Design
  • Level-4 Heterocyclic Systems
  • Postgraduate - Total Synthesis of Natural Products

Additional information

Awards

PhD(Cantab), MRSC, FRSE

Selected Recent Talks

  • “New Strategies for Rapid Construction of Fused Polycyclic Ethers and their Application to the Synthesis of the Gambieric Acids”. Plenary Lecture, International Chemical Congress of Pacific Basin Societies (Pacifichem), December 2005.
  • “Total Synthesis of Bioactive Polycyclic Terpenoid Natural Products of Terrestrial and Marine Origin”. Plenary Lecture, Groupe d’Etude de Chimie Organique (GECO) 47ème Edition, Merlimont, France, September 2006.
  • “Total Synthesis of Complex Polycyclic Marine Natural Products” A Celebration of Organic Chemistry, SCI Symposium, Novartis Institutes for Biomedical Research Research, Horsham, West Sussex, September 2006.
  • “Total Synthesis of Complex polycyclic Terpenoid Natural Products”. Plenary Lecture, AstraZeneca Awards in Organic Chemistry Symposium, Alderley Park, Cheshire, October 2006.
  • “Total Synthesis of Bioactive Ether-Bridged Marine Diterpene Natural Products”. Invited Lecture, Organic Division of the RSC: Heterocyclic and Synthesis Group 18th Lakeland Heterocyclic Symposium, Grasmere, Cumbria, May 2007.

External Appointments & Positions

  • Vice-President of the Organic Division of the Royal Society of Chemistry
  • UK representative of the Management Group for EU COST Action CM0804 – Chemical Biology with Natural Products
  • Glaxo Wellcome Award for Innovative Organic Chemistry 1996; Zeneca Award for Chemistry 1997; Pfizer Academic Award 2001; Novartis European Young Investigator Award in Chemistry 2004
  • External Examiner, University of Birmingham
  • EPSRC College and Panel Member

Stephen Clark