Professor Klaas Wynne
- Chair in Chemical Physics (School of Chemistry)
In the Chemical Photonics | Ultrafast/slow Chemical Physics group, we are interested in the fundamental chemical physics of liquids, proteins, and soft matter. Of particular interest are phase transitions such as liquid-liquid (polyamorphous) transitions and nucleation of new phases such as crystals. These phenomena are studied using ultrafast laser spectroscopy (from femtoseconds to nanoseconds) and novel microscopy methods for the laser manipulation of phases. Our recent work has been published in some of the top journals (Nature Chemistry, Nature Commun., JACS, JPCLett.) and receives funding through an ERC Advanced grant as well as grants from EPSRC, MRC, and Leverhulme.
- Walton, J. Bolling, A. Farrell, J. MacEwen, C. Syme, M. González Jiménez, H. Senn, C. Wilson, G. Cinque, and K. Wynne, ‘Polyamorphism mirrors polymorphism in the liquid–liquid transition of a molecular liquid’, J. Am. Chem. Soc. 142, 7591-7597 (2020). (https://doi.org/10.1021/jacs.0c01712)
- González-Jiménez, S.A. Babayan, P. Khazaeli, M. Doyle, F. Walton, E. Reedy, T. Glew, M. Viana, L. Ranford-Cartwright, A. Niang, D.J. Siria, F.O. Okumu, A. Diabaté, H.M. Ferguson, F. Baldini, and K. Wynne, ‘Prediction of malaria mosquito species and population age structure using mid-infrared spectroscopy and supervised machine learning’, Wellcome Open Res. 4, 76 (2019). (https://doi.org/10.12688/wellcomeopenres.15201.3)
- Walton, K. Wynne, ‘Control over phase separation and nucleation using a laser-tweezing potential’, Nat. Chem. 10, 506-510 (2018) (http://doi.org/10.1038/s41557-018-0009-8)
- Wynne, ‘The Mayonnaise Effect’, J. Phys. Chem. Lett. 8, 6189-6192 (2017). (http://doi.org/10.1021/acs.jpclett.7b03207)
- Ramakrishnan, M. González-Jiménez, A.J. Lapthorn, and K. Wynne, ‘Spectrum of slow and super-slow (picosecond to nanosecond) water dynamics around organic and biological solutes’, J. Phys. Chem. Lett. 8, 2964-2970 (2017). (http://dx.doi.org/10.1021/acs.jpclett.7b01127)
- Reichenbach, S.A. Ruddell, M. González-Jiménez, J. Lemes, D.A. Turton, D.J. France, and K. Wynne, ‘Phonon-like hydrogen-bond modes in protic ionic liquids’, J. Am. Chem. Soc. 139, 7160-7163 (2017). (http://dx.doi.org/10.1021/jacs.7b03036)
- González-Jiménez, G. Ramakrishnan, T. Harwood, A.J. Lapthorn, S.M. Kelly, E.M. Ellis, and K. Wynne, ‘Observation of coherent delocalised phonon-like modes in DNA under physiological conditions’, Nat. Commun., 7, 11799 (2016). (http://dx.doi.org/10.1038/ncomms11799)
- 2019-2024 ERC Advanced Grant, Laser control over crystal nucleation – CONTROL, £2872k (FEC), Wynne
- 2019-2022 Leverhulme RPG-2018-350, Delocalised phonon-like modes in organic and bio-molecules, £341k, Wynne, Lapthorn, Senn
- 2017-2019 MRC MR/P025501/1, Development of a new tool for malaria mosquito surveillance to improve vector control, £664k, H. Ferguson, K. Wynne, H. Ranson, F. Okumu
- 2016-2019 EPSRC EP/N007417/1 Mapping and controlling nucleation £562k K. Wynne, D. France
- 2015-2016 EPSRC EP/N508792/1 A Dynamic Perspective on Biomolecular Function and Reactivity £14k K. Wynne, A. Lapthorn, B.O. Smith, N.T. Hunt, M. Fedorov
- 2013-2016, EPSRC EP/K034995/1, "Solvation dynamics and structure around proteins and peptides: collective network motions or weak interactions", £546k, K. Wynne, , A. Lapthorn, S. Kelly.
- 2012-2015, EPSRC EP/J00975X/1, EP/J009733/1, "The structure and dynamics of water confined in nanoscale pools: the dynamic crossover", £586k, K. Wynne, N. Hunt.
- 2012-2015, EPSRC EP/J004790, EP/J004812, EP/J014478, "Liquid–liquid transitions in molecular liquids: from supramolecular structure to phase separation", £634k, K. Wynne, J. Sefcik.
- 2013, RSC, Faraday Discussion Meeting "Mesostructure and dynamics in liquids and solutions", K. Wynne, A. Soper (RAL), A. Angel (Arizona State U.), K. Seddon (Queen's U.), S. Meech (UEA), H.E. Stanley (Boston U.).
- 2010, ISIS 1010269, A liquid-liquid transition in supercooled Gallium (3 days on SANDALS), K. Wynne, F. Demmel, W.S. Howells, D.A. Turton
- 2008-2013, EPSRC EP/F06926X, Two-dimensional terahertz–IR spectroscopy: a unique probe of ultrafast hydrogen-bond dynamics of liquid water and model systems, £623k, K. Wynne, J. Karolin, D.J.S. Birch
- 2007-2011, EPSRC EP/E046541, Terahertz spectroscopy of aqueous ionic solutions to understand the role of hydrogen-bond network breaking and strengthening in the Hofmeister series, £470k, K. Wynne, N.T Hunt
- 2006-2011, EPSRC EP/D062861/1, Nanometrology for Molecular Science, Medicine and Manufacture, £3118k, Birch, Pickup, Faulds, O’Donnell, Smith, Martin, Wynne, Dawson, Girkin, Graham, Gnudi, Rolinski
- 2006-2011, SFC, Nanometrology for Molecular Science, Medicine and Manufacture, £1150k, Birch, Pickup, Faulds, O’Donnell, Smith, Martin, Wynne, Dawson, Girkin, Graham, Gnudi, Rolinski
- 2004-2007, EPSRC GR/S95510, A comparison of the THz-frequency vibrational spectra of (chiral) liquids obtained through ultrafast infrared and Raman spectroscopies, £252k, K. Wynne
- 2004-2005, Wolfson Foundation, Nanometrology of colloidal particles, £449k, Birch, Wynne, Smith, Graham
- 2004-2009, Leverhulme Trust F/00273/E, Surface-enhanced ultrafast Kerr-effect spectroscopy of dynamics in biomolecules, £125k, K. Wynne, D.J.S. Birch
- 2004-2007, EPSRC GR/S75369, Understanding the structural and dynamic basis of kinetics in biomolecules using novel ultrafast Raman techniques, £330k, K. Wynne, D.J.S. Birch, W.E. Smith, D. Graham, J.O. Karolin
- 2004-2005, SHEFC SRIF, Materials preparation and characterisation equipment, and solid-state ultrafast laser sources (SHEFC, Science Research Investment Fund), £470k, Several investigators including D.J.S. Birch and K. Wynne
- 2003-2006, EPSRC GR/S48110 & GR/S48127, Single Molecule Sensing in Clinical Medicine (EPSRC Adventure Fund), £528k, Birch, Pickup, Smith, Wynne, Graham, Gnudi, Rolinski
- 2003-2006, EPSRC GR/R97566, Using electromagnetic pulses emitted by ultrafast molecular currents for studying charge-transfer reactions, £211k, K. Wynne, D.A. Jaroszynski
- 2002-2006, EPSRC GR/R88090, Basic technology: Developing laser-plasma accelerators and coherent radiation sources as tools for time-resolved studies, £4270k, Jaroszynski, Burnett, Cairns, Dangor, Gillespie, Wark, Bingham, Poole, Norreys, Wynne, Hooker, Krushelnick, Walmsley
- 1999-2001, EPSRC GR/M75600, Ultrafast electron-energy loss/gain spectroscopy (fs-EELS/EEGS), £78k, K. Wynne, D.A. Jaroszynski
- 1999-2002, SHEFC RDG, X-ray to infrared sources for Strathclyde Terahertz to Optical Pulse Source (TOPS), £570k, D.A. Jaroszynski, A.D.R. Phelps, K. Wynne
- 1999-2003, PRF 34344 - AC6, Chemical reaction control with high-power femtosecond electrical pulses, £40k, K. Wynne
- 1999-2002, EPSRC GR/M52090, Study of superradiance and short pulse propagation in an underdense plasma, £406k, D.A. Jaroszynski, A.D.R. Phelps, K. Wynne
- 1999-2003, RS A20172, Femtosecond field emitter, £10k, K. Wynne
- 1999-2002, SHEFC , Strathclyde Synchronised Electron and High Power Ultra-Short Terahertz to Optical Pulse Source (TOPS), £530k, D.A. Jaroszynski, A.D.R. Phelps, K. Wynne
- 1999-2002, EPSRC GR/M39312, The solvent response to chemical reactions, £190k, K. Wynne
- 1997-1999, EPSRC GR/L91627, T-Ray near-field imaging, £51k, K. Wynne
- 1997-1999, EPSRC GR/K88002, Temporal and spectral dynamics of phonons in crystals excited using subpicosecond optical pulses, £193k, T.P.J. Han, K. Wynne
- 1996-1997, Strathclyde, Ultrafast reaction dynamics in proteins, £20k, K. Wynne
- 1997-1999, EPSRC GR/K88972, Fluorescence dynamics in confined water: application to the structure of silica hydrogels, £198k, D.J.S. Birch, K. Wynne
- Mitton, Joshua
Machine learning in spectroscopy
Recent marks of esteem
2018 - Awarded the RSC Chemical Dynamics Award for outstanding contributions to time-resolved spectroscopy
2017 - Appointed Associate Editor JACS
2015 - Elected Fellow of the Royal Society of Edinburgh (FRSE)
2013 - Elected Member of Faraday Division Council
2012 - Elected member of the editorial advisory board of the Journal of Physical Chemistry B
2012 - Elected a member of the EPSRC college of peer reviewers
2012 - Elected member of the board of Chemical Physics (Elsevier)
Recent professional activities
- Associate Editor of the Journal of the American Chemical Society (JACS) (2017-2020).
- Member of the Editorial Board of the Elsevier journal Chemical Physics (2012-present).
- Member of the editorial advisory board of the Journal of Physical Chemistry (2012-2015).
- Member appointment panel Tenured Lecturer position (Serra Hunter Programme) at the University of Barcelona (2016).
- Member of the Faraday Division council of the RSC (2013-2016).
- Member of the EPSRC college of peers (2012-present).
- Co-organiser of the international conference on Time-Resolved Vibrational Spectroscopy (TRVS), 2017, UK.
- Member of the scientific advisory committee of the annual general meeting of the European Molecular Liquids Group (EMLG) and Japanese Molecular Liquids Group (2012-2015).
- Member of the international organising committee of the international conference on Time-Resolved Vibrational Spectroscopy, TRVS (2009-present).
- Member programme committee for SPIE Photonics West (ultrafast phenomena in semiconductors and nanostructures), San Francisco, USA. (2009-2015)