Professor John McMurray
- Professor of Cardiology (Cardiovascular & Metabolic Health)
telephone:
01413303479
email:
John.McMurray@glasgow.ac.uk
RC217Level C2, School of Cardiovascular and Metabolic Health, BHF Glasgow CRC, Glasgow G12 8TA
Biography
John McMurray OBE, BSC (Hons), MB ChB (Hons), MD, FRCP, FESC, FACC, FAHA, FRSE, FMedSci
Professor McMurray is currently Professor of Medical Cardiology and honorary Consultant Cardiologist at the Queen Elizabeth University Hospital, Glasgow.
Professor McMurray served as the inaugural Eugene Braunwald Scholar in Cardiovascular Disease at the Brigham and Women’s Hospital, Boston, and visiting Professor of Medicine, Harvard University, Boston, Massachusetts USA 2010/2011. He is a Past-President of the Heart Failure Association of the ESC.
He is a Highly Cited Researcher (https://recognition.webofscience.com/awards/highly-cited/2021/) and has a H-index of >200 (https://scholar.google.com/citations?user=n0ZdRMoAAAAJ&hl=en). He is and has been involved in many guideline committees, including chairing the Task Force for 2012 ESC Guidelines on heart failure and was a member of the 2016 and 2021 Task Forces. Professor McMurray is an Associate Editor for JACC-Heart Failure and is also a member of the editorial board of several journals including the European Journal of Heart Failure, Diabetes Care and the New England Journal of Medicine, and Guest Editor for Circulation & Circulation: Heart Failure. He is the Congress Programme Committee Chair for the European Society of Cardiology 2023/2024 and European Society of Cardiology Board Member.
Professor McMurray was a member of the recent European Society of Cardiology (ESC) Task Force that created a policy on gender https://www.escardio.org/static-file/Escardio/About%20the%20ESC/Documents/European%20Society%20of%20Cardiology%20Gender%20Policy.pdf and the NEJM policy group on diversity in research studies https://www.nejm.org/doi/full/10.1056/NEJMe2114651
He has won several awards, including the Stokes Medal of the Irish Cardiac Society. In June 2015, Professor John McMurray and Professor Salim Yusuf (McMaster University, Hamilton Ontario, Canada) were jointly awarded the 8th Arrigo Recordati International Prize for Scientific Research (for outstanding contributions in secondary prevention and risk reduction strategies in patients with cardiovascular diseases).
Professor McMurray is the recipient of the Mackenzie Medal, which is awarded by the British Cardiovascular Society in recognition of outstanding service to British Cardiology. He is also the recipient of the Louis and Artur Lucian Award for Research in Circulatory Diseases, which is awarded each year by McGill University, Montreal. This international award recognises outstanding research in the field of circulatory diseases by a scientific investigator, or group of investigators, whose contribution to knowledge in this field is deemed worthy of special recognition.
Professor McMurray was awarded an (honorary) OBE in 2019 by Her Majesty the Queen, in recognition of his services to cardiovascular research. In 2020 he was awarded the Gold Medal of the European Society of Cardiology, which the society describes as “the highest honour it can bestow on exceptional scientists for their contribution to cardiovascular medicine”. In 2021 Professor McMurray received the Rigshospitalet’s International KFJ Award. In 2023 he was made an honorary fellow of the Japanese Circulation Society. Professor McMurray has been invited to lecture widely at many international congresses and delivered many several named lectures.
Research interests
Research Theme: Cardiac Diseases
Prof McMurray’s primary research interests are in heart failure and the cardiovascular consequences of diabetes and chronic kidney disease, with a focus on clinical trials. He is, or was, the principal investigator, member of the executive committee or steering committee member for several large trials in his areas of interest including the completed CHARM-Added, CORONA, I-Preserve, EMPHASIS-HF, PARADIGM-HF, ATMOSPHERE, Harmony-Outcomes, PARAGON-HF, GALACTIC-HF, DAPA-HF, DAPA-CKD, ASCEND-D and -ND trials, DELIVER, the ongoing FINEARTS-HF trial and the recently announced FINALITY trial.
DAPA-HF trial website: www.dapatrial.org
DELIVER trial website: www.delivertrial.org
He has been a member and chair of many guideline committees and the lead author of the World Health Organization and first Scottish Intercollegiate Guidelines Network Guidelines on the Management of HF. In addition, he was a member of the 2008 ESC HF Guidelines Task Force, and Chair of the 2012 Task Force and member of the 2013 American College of Cardiology/American Heart Association HF Guidelines Committee and the 2014 National Institute for Health and Care Excellence (NICE) Acute HF Guideline Committee.
He is a member of NICE Appraisal Committee A and a member of the editorial board of the New England Journal of Medicine and sit on the editorial board of several leading cardiovascular journals, including the European Heart Journal (Associate Editor) and Circulation.
In 2013, Prof McMurray was identified as one of the 400 most influential biomedical researchers in the world and the only cardiovascular researcher on this list from the UK (Boyack KW, Klavans R, Sorensen AA, Ioannidis JP. A list of highly influential biomedical researchers,1996-2011. Eur J Clin Invest. 2013; 43:1339-65). I have also been included in the 2014, 2016, 2017 and 2018 Highly Cited Researchers listing and one of The World's Most Influential Scientific Minds: 2014 by Thomson Reuters.
Google Scholar
https://www.webofscience.com/wos/author/record/B-2467-2013
https://research.com/scientists-rankings/best-scientists/gb
Research groups
Publications
2024
Osmanska, J., Petrie, M. C. , Docherty, K. F. , Lee, M. M.Y. , McMurray, J. J.V. and Campbell, R. (2024) Subcutaneous furosemide in heart failure: a systematic review. European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae083) (Accepted for Publication)
Lu, H. et al. (2024) Visit‐to‐visit changes in heart rate in heart failure: A pooled participant‐level analysis of the PARADIGM‐HF and PARAGON‐HF trials. European Journal of Heart Failure, (doi: 10.1002/ejhf.3487) (PMID:39439294) (Early Online Publication)
Docherty, K. F. et al. (2024) Wearable accelerometer-derived measures of physical activity in heart failure: insights from the DETERMINE trials. Journal of Cardiac Failure, (Accepted for Publication)
Chatur, S. et al. (2024) Sacubitril/valsartan in patients with heart failure and deterioration in eGFR to <30 mL/min/1.73 m2. JACC: Heart Failure, 12(10), pp. 1692-1703. (doi: 10.1016/j.jchf.2024.03.014) (PMID:38842957)
Docherty, K. F. et al. (2024) Effect of dapagliflozin on accelerometer-based measures of physical activity in patients with heart failure: an analysis of the DETERMINE trials. Circulation: Heart Failure, 17(10), e012349. (doi: 10.1161/CIRCHEARTFAILURE.124.012349) (PMID:39212948) (PMCID:PMC11472896)
Wang, X. et al. (2024) Sex differences in cardiac structure and function following acute myocardial infarction: Insights from the PARADISE‐MI echocardiographic substudy. European Journal of Heart Failure, (doi: 10.1002/ejhf.3472) (PMID:39315586) (Early Online Publication)
Jhund, P. S. et al. (2024) Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis. Lancet, 404(10458), pp. 1119-1131. (doi: 10.1016/S0140-6736(24)01733-1) (PMID:39232490)
Pabon, M. A. et al. (2024) In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3410) (PMID:39300780) (Early Online Publication)
Lu, H. et al. (2024) Sacubitril/valsartan reduces incident anaemia and iron therapy utilization in heart failure: The PARAGON‐HF trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3414) (PMID:39217577) (Early Online Publication)
Abdin, A. et al. (2024) Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: an analysis of DAPA-HF and DELIVER. European Journal of Heart Failure, 26(9), pp. 1952-1963. (doi: 10.1002/ejhf.3350) (PMID:39016033)
Butt, J. et al. (2024) Dapagliflozin and timing of prior heart failure hospitalization a patient-level meta-analysis of DAPA-HF and DELIVER. JACC: Heart Failure, 12(9), pp. 1586-1599. (doi: 10.1016/j.jchf.2024.01.018) (PMID:38573262)
Butt, J. H. et al. (2024) Therapeutic effects of heart failure medical therapies on standardized kidney outcomes: Comprehensive individual participant-level analysis of 6 randomized clinical trials. Circulation, (doi: 10.1161/circulationaha.124.071110) (PMID:39217458) (Accepted for Publication)
Mc Causland, F. R. et al. (2024) Acute changes in kidney function and outcomes following an acute myocardial infarction: Insights from PARADISE-MI. European Journal of Heart Failure, 26(9), pp. 1984-1992. (doi: 10.1002/ejhf.3386) (PMID:39056455)
Matsumoto, S. et al. (2024) Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3383) (PMID:39215677) (Early Online Publication)
Yang, M. et al. (2024) Clinical characteristics and outcomes of patients aged 80 years and over with heart failure: Need for better treatment. European Journal of Heart Failure, (doi: 10.1002/ejhf.3417) (PMID:39169481) (Early Online Publication)
Butt, J. H. et al. (2024) Anthropometric measures and long‐term mortality in non‐ischaemic heart failure with reduced ejection fraction: Questioning the obesity paradox. European Journal of Heart Failure, (doi: 10.1002/ejhf.3424) (PMID:39155576) (Early Online Publication)
Cleland, J. et al. (2024) The IRONMAN trial of intravenous iron for heart failure. Adjudication of hospitalizations and deaths. Journal of the American College of Cardiology, (Accepted for Publication)
Carberry, J. et al. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure, 11(4), pp. 2001-2012. (doi: 10.1002/ehf2.14830) (PMID:38715187) (PMCID:PMC11287338)
Docherty, K. F. , McMurray, J. J.V. , Kalra, P., Cleland, J. G.F. , Lang, N. N. , Petrie, M. C. , Robertson, M. and Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, 11(4), pp. 1875-1879. (doi: 10.1002/ehf2.14742) (PMID:38549192) (PMCID:PMC11287326)
Kondo, T. et al. (2024) Low natriuretic peptide levels and outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 12(8), pp. 1442-1455. (doi: 10.1016/j.jchf.2024.04.027) (PMID:38904646)
Lam, C. S.P. et al. (2024) Balcinrenone plus dapagliflozin in patients with heart failure and chronic kidney disease: Results from the phase 2b MIRACLE trial. European Journal of Heart Failure, 26(8), pp. 1727-1735. (doi: 10.1002/ejhf.3294) (PMID:38783712)
Lassen, M. C.H. et al. (2024) Cardiovascular‐kidney‐metabolic overlap in heart failure with preserved ejection fraction: Cardiac structure and function, clinical outcomes, and response to sacubitril/valsartan in PARAGON‐HF. European Journal of Heart Failure, 26(8), pp. 1762-1774. (doi: 10.1002/ejhf.3304) (PMID:38932589)
Matsumoto, S. et al. (2024) Relevant adverse events and drug discontinuation of sacubitril/valsartan in a real-world Japanese cohort: REVIEW-HF registry. Journal of Cardiology, 84(2), pp. 133-140. (doi: 10.1016/j.jjcc.2023.11.005) (PMID:38000538)
O'Hara, D. V., Lam, C. S.P., McMurray, J. J.V. , Yi, T. W., Hocking, S., Dawson, J., Raichand, S., Januszewski, A. S. and Jardine, M. J. (2024) Applications of SGLT2 inhibitors beyond glycaemic control. Nature Reviews Nephrology, (doi: 10.1038/s41581-024-00836-y) (PMID:38671190)
Yang, M. et al. (2024) Geographical variation in patient characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction. European Journal of Heart Failure, 26(8), pp. 1788-1803. (doi: 10.1002/ejhf.3352) (PMID:38923118)
Zahir Anjum, D. et al. (2024) Use of medical therapy and risk of clinical events according to frailty in heart failure patients – A real‐life cohort study. European Journal of Heart Failure, 26(8), pp. 1717-1726. (doi: 10.1002/ejhf.3249) (PMID:38700461)
Espersen, C. et al. (2024) Predictors of heart failure readmission and all-cause mortality in patients with acute heart failure. International Journal of Cardiology, 406, 132036. (doi: 10.1016/j.ijcard.2024.132036) (PMID:38599465)
Ostrominski, J. W. et al. (2024) Cardiovascular-kidney-metabolic overlap in heart failure with mildly reduced or preserved ejection fraction a trial-level analysis. Journal of the American College of Cardiology, 84(2), pp. 223-228. (doi: 10.1016/j.jacc.2024.05.005) (PMID:38744407)
Yang, M. et al. (2024) Dapagliflozin and quality of life measured using the EuroQol 5-Dimension questionnaire in patients with HFrEF and HFmrEF/HFpEF. European Journal of Heart Failure, 26(7), pp. 1524-1538. (doi: 10.1002/ejhf.3263) (PMID:38700986)
Conrad, N. et al. (2024) Temporal trends and patterns in cardiovascular disease incidence: a population-based study in 22 million individuals. British Medical Journal, 385, e078523. (doi: 10.1136/bmj-2023-078523) (PMID:38925788) (PMCID:PMC11203392)
Shen, L. et al. (2024) Revisiting race and the benefit of RAS blockade in heart failure. A meta-analysis of randomized clinical trials. JAMA: Journal of the American Medical Association, 331(24), 2094. (doi: 10.1001/jama.2024.6774) (PMID:38809561)
Matsumoto, S. et al. (2024) Mineralocorticoid receptor antagonists in patients with heart failure and impaired renal function. Journal of the American College of Cardiology, 83(24), pp. 2426-2436. (doi: 10.1016/j.jacc.2024.03.426) (PMID:38739064)
Friday, J. M. et al. (2024) Loop diuretic utilisation with or without heart failure: impact on prognosis. European Heart Journal, (doi: 10.1093/eurheartj/ehae345) (PMID:38845446) (Early Online Publication)
Chatur, S. et al. (2024) Effects of sacubitril/valsartan across the spectrum of renal impairment in patients with heart failure. Journal of the American College of Cardiology, 83(22), pp. 2148-2159. (doi: 10.1016/j.jacc.2024.03.392) (PMID:38588927)
Curtain, J. P. et al. (2024) Measuring congestion with a non-invasive monitoring device in heart failure and haemodialysis: CONGEST-HF. European Journal of Heart Failure, 26(6), pp. 1383-1392. (doi: 10.1002/ejhf.3290) (PMID:38741283)
Pabón, M. A. et al. (2024) Sex differences in heart failure with improved ejection fraction. JACC: Heart Failure, 12(6), pp. 1119-1122. (doi: 10.1016/j.jchf.2024.03.011) (PMID:38661586)
Solomon, S. D. et al. (2024) Baseline characteristics of patients with heart failure with mildly reduced or preserved ejection fraction: The FINEARTS‐HF trial. European Journal of Heart Failure, 26(6), pp. 1334-1346. (doi: 10.1002/ejhf.3266) (PMID:38733212)
Vaduganathan, M. et al. (2024) Finerenone in patients with heart failure with mildly reduced or preserved ejection fraction: Rationale and design of the FINEARTS‐HF trial. European Journal of Heart Failure, 26(6), pp. 1324-1333. (doi: 10.1002/ejhf.3253) (PMID:38742248)
Kondo, T. et al. (2024) Dapagliflozin and days of full health lost through death, hospitalization, and impaired well-being in DAPA-HF. Journal of the American College of Cardiology, 83(20), pp. 1973-1986. (doi: 10.1016/j.jacc.2024.03.385) (PMID:38537918)
Davis, J. A., Booth, D., McEwan, P., Solomon, S. D., McMurray, J. J.V. , de Boer, R. A., Comin‐Colet, J., Bachus, E. and Chen, J. (2024) Cost-effectiveness of dapagliflozin for patients with heart failure across the spectrum of ejection fraction: a pooled analysis of DAPA-HF and DELIVER data. European Journal of Heart Failure, 26(3), pp. 664-673. (doi: 10.1002/ejhf.3197) (PMID:38509642)
Lassen, M. C. H. et al. (2024) Effect of dapagliflozin in patients with diabetes and heart failure with mildly reduced or preserved ejection fraction according to background glucose‐lowering therapy: a pre‐specified analysis of the DELIVER trial. European Journal of Heart Failure, 26(7), pp. 1539-1548. (doi: 10.1002/ejhf.3269) (PMID:38745498)
Foà, A. et al. (2024) Sacubitril/Valsartan-related hypotension in patients with heart failure and preserved or mildly reduced ejection fraction. Journal of the American College of Cardiology, 83(18), pp. 1731-1739. (doi: 10.1016/j.jacc.2024.02.035) (PMID:38537919)
McDowell, K. et al. (2024) Prognostic models for mortality and morbidity in heart failure with preserved ejection fraction. JAMA Cardiology, 9(5), 457. (doi: 10.1001/jamacardio.2024.0284) (PMID:38536153)
Gilbert, M. P., Skelly, J., Hernandez, A. F., Green, J. B., Krychtiuk, K. A., Granger, C. B., Leiter, L. A., McMurray, J. J.V. , Del Prato, S. and Pratley, R. E. (2024) Effect of albiglutide on cardiovascular outcomes in older adults: a post hoc analysis of a randomized controlled trial. Diabetes, Obesity and Metabolism, 26(5), pp. 1714-1722. (doi: 10.1111/dom.15479) (PMID:38317618)
Kondo, T. et al. (2024) A hierarchical kidney outcome using win statistics in patients with heart failure from the DAPA-HF and DELIVER trials. Nature Medicine, 30(5), pp. 1432-1439. (doi: 10.1038/s41591-024-02941-8) (PMID:38710952) (PMCID:PMC11108780)
Matsumoto, S. et al. (2024) Effects of sacubitril/valsartan according to polypharmacy status in PARAGON‐HF. European Journal of Heart Failure, 26(5), pp. 1125-1138. (doi: 10.1002/ejhf.3223) (PMID:38587090)
Cleland, J. G.F. et al. (2024) Intravenous iron for heart failure, iron deficiency definitions, and clinical response: the IRONMAN trial. European Heart Journal, 45(16), pp. 1410-1426. (doi: 10.1093/eurheartj/ehae086) (PMID:38446126) (PMCID:PMC11032711)
Heerspink, H. J.L. et al. (2024) Dapagliflozin and blood pressure in patients with chronic kidney disease and albuminuria. American Heart Journal, 270, pp. 125-135. (doi: 10.1016/j.ahj.2024.02.006) (PMID:38367893)
Minamisawa, M. et al. (2024) Clinical implications of subclinical left ventricular dysfunction in heart failure with preserved ejection fraction: the PARAGON‐HF study. European Journal of Heart Failure, 26(4), pp. 871-881. (doi: 10.1002/ejhf.3167) (PMID:38369856)
Monzo, L. et al. (2024) High risk of stroke in patients with worsening heart failure, reduced ejection fraction, coronary heart disease and sinus rhythm: risk prediction score analysis from the COMMANDER-HF trial. Journal of Cardiac Failure, 30(4), pp. 618-623. (doi: 10.1016/j.cardfail.2023.11.020) (PMID:38122924)
Peikert, A. et al. (2024) Contemporary use and implications of beta-blockers in patients with HFmrEF or HFpEF: the DELIVER Trial. JACC: Heart Failure, 12(4), pp. 631-644. (doi: 10.1016/j.jchf.2023.09.007) (PMID:37767674)
Peikert, A. et al. (2024) Dapagliflozin in patients with heart failure and previous myocardial infarction: A participant‐level pooled analysis of DAPA-HF and DELIVER. European Journal of Heart Failure, 26(4), pp. 912-924. (doi: 10.1002/ejhf.3184) (PMID:38487939)
Knigge, P. et al. (2024) Temporal trends in the initiation of dialysis among patients with heart failure with or without diabetes: a nationwide study from 2002 to 2016. Journal of the American Heart Association, 13(6), e032539. (doi: 10.1161/JAHA.123.032539) (PMID:38471834) (PMCID:PMC11009989)
Bhatt, A. S. et al. (2024) Cost effectiveness of dapagliflozin for heart failure across the spectrum of ejection fraction: an economic evaluation based on pooled, individual participant data from the DELIVER and DAPA-HF trials. Journal of the American Heart Association, 13(5), e032279. (doi: 10.1161/JAHA.123.032279) (PMID:38390793) (PMCID:PMC10944049)
Mann, D. L. et al. (2024) Angiotensin receptor-neprilysin inhibition in patients with STEMI vs NSTEMI. Journal of the American College of Cardiology, 83(9), pp. 904-914. (doi: 10.1016/j.jacc.2024.01.002) (PMID:38418004)
Adamo, M. et al. (2024) Tricuspid regurgitation and clinical outcomes in heart failure with reduced ejection fraction. JACC: Heart Failure, 12(3), pp. 552-563. (doi: 10.1016/j.jchf.2023.11.018) (PMID:38300212)
Dimond, M. G. et al. (2024) Left ventricular ejection fraction and the future of heart failure phenotyping. JACC: Heart Failure, 12(3), pp. 451-460. (doi: 10.1016/j.jchf.2023.11.005) (PMID:38099892)
Butt, J. H. et al. (2024) Heart failure, investigator-reported sleep apnea and dapagliflozin: A patient-level pooled meta-analysis of DAPA-HF and DELIVER. Journal of Cardiac Failure, 30(3), pp. 436-448. (doi: 10.1016/j.cardfail.2023.08.027) (PMID:38104937)
Ferguson, L. D. , Molenberghs, G., Verbeke, G., Rahimi, K., Rao, S., McInnes, I. B. , McMurray, J. J.V. , Sattar, N. and Conrad, N. (2024) Gout and incidence of 12 cardiovascular diseases: a case–control study including 152 663 individuals with gout and 709 981 matched controls. Lancet Rheumatology, 6(3), e156-e167. (doi: 10.1016/S2665-9913(23)00338-7)
Wang, X. et al. (2024) Effects of dapagliflozin in patients in Asia: a post hoc subgroup analysis from the DELIVER trial. JACC: Asia, 4(2), pp. 108-118. (doi: 10.1016/j.jacasi.2023.10.005) (PMID:38371292) (PMCID:PMC10866733)
Brum, W. S., Docherty, K. F. , Ashton, N. J., Zetterberg, H., Hansson, O., McMurray, J. J. V. and Blennow, K. (2024) Effect of neprilysin inhibition on Alzheimer disease plasma biomarkers: a secondary analysis of a randomized clinical trial. JAMA Neurology, 81(2), pp. 197-200. (doi: 10.1001/jamaneurol.2023.4719) (PMID:38109077) (PMCID:PMC10728797)
Butt, J. H. et al. (2024) Heart failure with preserved ejection fraction, red cell distribution width, and sacubitril/valsartan. ESC Heart Failure, 11(1), pp. 65-77. (doi: 10.1002/ehf2.14558) (PMID:37813587) (PMCID:PMC10804200)
Owen, R. et al. (2024) Sex differences in the clinical presentation and natural history of dilated cardiomyopathy. JACC: Heart Failure, 12(2), pp. 352-363. (doi: 10.1016/j.jchf.2023.10.009) (PMID:38032570) (PMCID:PMC10857810)
Vart, P. et al. (2024) Efficacy and safety of dapagliflozin in patients with chronic kidney disease across the spectrum of frailty. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 79(2), glad181. (doi: 10.1093/gerona/glad181) (PMID:37527836) (PMCID:PMC10809037)
Vardeny, O. et al. (2024) Dapagliflozin and mode of death in heart failure with improved ejection fraction: A post hoc analysis of the DELIVER trial. JAMA Cardiology, 9(3), pp. 283-289. (doi: 10.1001/jamacardio.2023.5318) (PMID:38265835) (PMCID:PMC10809142)
Omerovic, E. et al. (2024) Pragmatic randomized controlled trials: strengthening the concept through a robust international collaborative network: PRIME-9-pragmatic research and innovation through multinational experimentation. Trials, 25, 80. (doi: 10.1186/s13063-024-07935-y) (PMID:38263138) (PMCID:PMC10807265)
Petrie, M. C. et al. (2024) Pulmonary congestion and left ventricular dysfunction after myocardial infarction: insights from the PARADISE-MI trial. Circulation, 149(4), pp. 335-38. (doi: 10.1161/CIRCULATIONAHA.123.066163) (PMID:38252738)
Docherty, K. F. et al. (2024) The effect of omecamtiv mecarbil in hospitalized patients as compared with outpatients with HFrEF: an analysis of GALACTIC-HF. Journal of Cardiac Failure, 30(1), pp. 26-35. (doi: 10.1016/j.cardfail.2023.08.020) (PMID:37683911)
Lala, A. et al. (2024) Standardized definitions for evaluation of acute decompensated heart failure therapies: HF-ARC expert panel paper. JACC: Heart Failure, 12(1), pp. 1-15. (doi: 10.1016/j.jchf.2023.09.030) (PMID:38069997)
Lee, M. M.Y. , Kondo, T., Campbell, R. T., Petrie, M. C. , Sattar, N. , Solomon, S. D., Vaduganathan, M., Jhund, P. S. and McMurray, J. J.V. (2024) Effects of Renin-Angiotensin system blockers on outcomes from COVID-19: a systematic review and meta-analysis of randomised controlled trials. European Heart Journal: Cardiovascular Pharmacotherapy, 10(1), pp. 68-80. (doi: 10.1093/ehjcvp/pvad067) (PMID:37740450) (PMCID:PMC10766905)
McDowell, K., Adamson, C., Jackson, C., Campbell, R., Welsh, P. , Petrie, M. C. , McMurray, J. J.V. , Jhund, P. and Herring, N. (2024) Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes. European Journal of Heart Failure, 26(1), pp. 107-116. (doi: 10.1002/ejhf.3085) (PMID:37937329)
Osmanska, J. et al. (2024) A novel, small-volume subcutaneous furosemide formulation delivered by an abdominal patch infusor device in patients with heart failure: results of two phase I studies. European Heart Journal: Cardiovascular Pharmacotherapy, 10, pp. 35-44. (doi: 10.1093/ehjcvp/pvad073) (PMID:37804170) (PMCID:PMC10766906)
Pellicori, P. et al. (2024) Impact of vasodilators on diuretic response in patients with congestive heart failure: a mechanistic trial of cimlanod (BMS‐986231). European Journal of Heart Failure, 26(1), pp. 142-151. (doi: 10.1002/ejhf.3077) (PMID:37990754)
Schou, M. et al. (2024) Sacubitril/valsartan compared to ramipril in high‐risk post‐myocardial infarction patients stratified according to use of mineralocorticoid receptor antagonists: insight from the PARADISE MI trial. European Journal of Heart Failure, 26(1), pp. 130-139. (doi: 10.1002/ejhf.3079) (PMID:37933184)
2023
Ostrominski, J. W. et al. (2023) Dapagliflozin and apparent treatment-resistant hypertension in heart failure with mildly reduced or preserved ejection fraction: The DELIVER trial. Circulation, 148(24), pp. 1945-1957. (doi: 10.1161/CIRCULATIONAHA.123.065254) (PMID:37830208)
McMurray, J. J.V. et al. (2023) Effect of Dapagliflozin Versus Placebo on Symptoms and 6-Minute Walk Distance in Patients With Heart Failure: The DETERMINE Randomized Clinical Trials. Circulation, (doi: 10.1161/CIRCULATIONAHA.123.065061) (PMID:38059368) (Early Online Publication)
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Dobbin, S. J.H. , Shen, L., Petrie, M. C. , Packer, M., Solomon, S. D., McMurray, J. J.V. , Lang, N. N. and Jhund, P. S. (2023) Characteristics and outcomes of patients with a history of cancer recruited to heart failure trials. European Journal of Heart Failure, 25(4), pp. 488-496. (doi: 10.1002/ejhf.2818) (PMID:36919816)
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Conrad, N. and McMurray, J. J.V. (2023) Cardiovascular risk in systemic autoimmune diseases – Authors' reply. Lancet, 401(10370), p. 22. (doi: 10.1016/S0140-6736(22)02426-6) (PMID:36610766) (PMCID:36041475)
Chatur, S., Claggett, B. L., Vardeny, O., Jering, K., Desai, A. S., Pfeffer, M. A., Lefkowitz, M., McMurray, J. J.V. , Solomon, S. D. and Vaduganathan, M. (2023) Sacubitril/valsartan and loop diuretic requirement in heart failure with preserved ejection fraction in the PARAGON‐HF trial. European Journal of Heart Failure, 25(1), pp. 87-94. (doi: 10.1002/ejhf.2703) (PMID:36181769)
Lee, M. M.Y. , Campbell, R. T., Claggett, B. L., Lewis, E. F., Docherty, K. F. , Lindner, M., Liu, J., Solomon, S. D., McMurray, J. J.V. and Platz, E. (2023) Health‐related quality of life in acute heart failure: association between patient‐reported symptoms and markers of congestion. European Journal of Heart Failure, 25(1), pp. 54-60. (doi: 10.1002/ejhf.2699) (PMID:36161429) (PMCID:PMC9892176)
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Sattar, N. , McMurray, J. J. V. , McInnes, I. B. , Aroda, V. R. and Lean, M. E. J. (2023) Treating chronic diseases without tackling excess adiposity promotes multimorbidity. Lancet Diabetes and Endocrinology, 11(1), pp. 58-62. (doi: 10.1016/S2213-8587(22)00317-5) (PMID:36460014)
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Talha, K. M., Butler, J., Greene, S. J., Aggarwal, R., Anker, S. D., Claggett, B. L., Solomon, S. D., McMurray, J. J.V. , Vaduganathan, M. and Fonarow, G. C. (2023) Population-level implications of sodium-glucose cotransporter-2 inhibitors for heart failure with preserved ejection fraction in the US. JAMA Cardiology, 8(1), pp. 66-73. (doi: 10.1001/jamacardio.2022.4348) (PMID:36334258)
2022
Singh, A. K. et al. (2022) Analysis of on-treatment cancer safety events with daprodustat versus conventional erythropoiesis-stimulating agents – post hoc analyses of the ASCEND-ND and ASCEND-D trials. Nephrology Dialysis Transplantation, (doi: 10.1093/ndt/gfac342) (PMID:36565721) (Early Online Publication)
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Bowman, L. et al. (2022) Randomized trials fit for the 21st century. A joint opinion from the European Society of Cardiology, American Heart Association, American College of Cardiology, and the World Heart Federation. European Heart Journal, 44(11), pp. 931-934. (doi: 10.1093/eurheartj/ehac633) (PMID:36525339) (PMCID:PMC10011328)
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Adamson, C., Jhund, P. S. and McMurray, J. J.V. (2022) Reply to 'the 50 shades of bilirubin'. Letter regarding the article 'liver tests and outcomes in heart failure with reduced ejection fraction: findings from DAPA-HF'. European Journal of Heart Failure, 24(11), pp. 2206-2207. (doi: 10.1002/ejhf.2683) (PMID:36097136)
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Adamson, C. et al. (2022) Liver tests and outcomes in heart failure with reduced ejection fraction: findings from DAPA-HF. European Journal of Heart Failure, 24(10), pp. 1856-1868. (doi: 10.1002/ejhf.2649) (PMID:36054568) (PMCID:PMC9805158)
Bedrouni, W. et al. (2022) Timing of statistical benefit of mineralocorticoid receptor antagonists among patients with heart failure and post-myocardial infarction. Circulation: Heart Failure, 15(10), pp. 988-990. (doi: 10.1161/CIRCHEARTFAILURE.121.009295) (PMID:35924555)
Berwanger, O. et al. (2022) Sacubitril/valsartan versus ramipril for patients with acute myocardial infarction: win‐ratio analysis of the PARADISE‐MI trial. European Journal of Heart Failure, 24(10), pp. 1918-1927. (doi: 10.1002/ejhf.2663) (PMID:36054480)
Chatur, S. et al. (2022) Longitudinal trajectories in renal function before and after heart failure hospitalization among patients with HFpEF in the PARAGON‐HF trial. European Journal of Heart Failure, 24(10), pp. 1906-1914. (doi: 10.1002/ejhf.2638) (PMID:35895867)
Claggett, B. L., McCaw, Z. R., Tian, L., McMurray, J. J.V. , Jhund, P. S. , Uno, H., Pfeffer, M. A., Solomon, S. D. and Wei, L.-J. (2022) Quantifying treatment effects in trials with multiple event-time outcomes. NEJM Evidence, 1(10), (doi: 10.1056/EVIDoa2200047)
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McDowell, K., Jhund, P. S. and McMurray, J. J.V. (2022) Reply to 'sodium-glucose cotransporter 2 inhibitor treatment lowers serum uric acid in patients with heart failure with reduced ejection fraction - lessons from clinical trials'. European Journal of Heart Failure, 24(10), p. 1994. (doi: 10.1002/ejhf.2686) (PMID:36093864)
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Welsh, P. et al. (2022) Reference ranges for NT-proBNP (N-terminal pro-B-type natriuretic peptide) and risk factors for higher NT-proBNP concentrations in a large general population cohort. Circulation: Heart Failure, 15(10), pp. 957-967. (doi: 10.1161/CIRCHEARTFAILURE.121.009427) (PMID:36098049) (PMCID:PMC9561238)
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Conrad, N., Verbeke, G., Molenberghs, G., Goetschalckx, L., Callender, T., Cambridge, G., Mason, J. C., Rahimi, K., McMurray, J. J.V. and Verbakel, J. Y. (2022) Autoimmune diseases and cardiovascular risk: a population-based study on 19 autoimmune diseases and 12 cardiovascular diseases in 22 million individuals in the UK. Lancet, 400(10354), pp. 733-743. (doi: 10.1016/S0140-6736(22)01349-6) (PMID:36041475)
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2021
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Lee, M. M.Y. , McMurray, J. J.V. , Jhund, P. S. , Petrie, M. C. and Sattar, N. (2021) Response by Lee et al to letter regarding article, "Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)". Circulation, 144(3), e40. (doi: 10.1161/CIRCULATIONAHA.121.055067) (PMID:34279995)
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Espersen, C. et al. (2021) Sex differences in congestive markers in patients hospitalized for acute heart failure. ESC Heart Failure, 8(3), pp. 1784-1795. (doi: 10.1002/ehf2.13300) (PMID:33709520) (PMCID:PMC8120385)
Jering, K. S. et al. (2021) Prospective ARNI versus ACE inhibitor trial to DetermIne Superiority in reducing heart failure Events after Myocardial Infarction (PARADISE‐MI): design and baseline characteristics. European Journal of Heart Failure, 23(6), pp. 1040-1048. (doi: 10.1002/ejhf.2191) (PMID:33847047)
Packer, M. and McMurray, J. J.V. (2021) Rapid evidence-based sequencing of foundational drugs for heart failure and a reduced ejection fraction. European Journal of Heart Failure, 23(6), pp. 882-894. (doi: 10.1002/ejhf.2149) (PMID:33704874) (PMCID:PMC8360176)
Sørensen, T. B. et al. (2021) The effect of the cardiac myosin activator, omecamtiv mecarbil, on right ventricular structure and function in chronic systolic heart failure (COSMIC-HF). European Journal of Heart Failure, 23(6), pp. 1052-1056. (doi: 10.1002/ejhf.2181) (PMID:33826209)
Beggs, S. A.S. , Jhund, P. S. and McMurray, J. J.V. (2021) Anticoagulation, atherothrombosis, and heart failure: lessons from COMMANDER-HF and CORONA. European Heart Journal, 42(20), e5-e7. (doi: 10.1093/eurheartj/ehy609) (PMID:30357375)
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McMurray, J. J.V. , Solomon, S. D., Docherty, K. F. and Jhund, P. S. (2021) The Dapagliflozin And Prevention of Adverse outcomes in Heart Failure trial (DAPA-HF) in context. European Heart Journal, 42(13), pp. 1199-1202. (doi: 10.1093/eurheartj/ehz916) (PMID:31898736) (PMCID:PMC8014512)
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Dewan, P. et al. (2021) Effects of dapagliflozin in heart failure with reduced ejection fraction, and chronic obstructive pulmonary disease: an analysis of DAPA-HF. European Journal of Heart Failure, 23(4), pp. 632-643. (doi: 10.1002/ejhf.2083) (PMID:33368858) (PMCID:PMC8247863)
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McMurray, J. J.V. and Docherty, K. F. (2021) SOLOIST-WHF: Sodium-glucose cotransporter 2 (SGLT2) inhibitors should be initiated in patients hospitalised with worsening heart failure. European Journal of Heart Failure, 23(1), pp. 27-30. (doi: 10.1002/ejhf.2075) (PMID:33283384)
2020
Felker, G. M., Solomon, S. D., McMurray, J. J.V. , Cleland, J. G.F. , Abbasi, S. A., Malik, F. I., Zhang, H., Globe, G. and Teerlink, J. R. (2020) Effects of omecamtiv mecarbil on symptoms and health-related quality of life in patients with chronic heart failure: results from the COSMIC-HF study. Circulation: Heart Failure, 13(12), e007814. (doi: 10.1161/CIRCHEARTFAILURE.120.007814) (PMID:33176437) (PMCID:PMC7742205)
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Wamil, M., McMurray, J. J.V. , Scott, C. A.B., Coleman, R. L., Sun, Y., Standl, E., Rydén, L. and Holman, R. R. (2020) Predicting heart failure events in patients with coronary heart disease and impaired glucose tolerance: insights from the Acarbose Cardiovascular Evaluation (ACE) trial. Diabetes Research and Clinical Practice, 170, 108488. (doi: 10.1016/j.diabres.2020.108488) (PMID:33035598)
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Vaduganathan, M., Vardeny, O., Michel, T., McMurray, J. J.V. , Pfeffer, M. A. and Solomon, S. D. (2020) Renin–Angiotensin–Aldosterone System inhibitors in patients with Covid-19. New England Journal of Medicine, 382(17), pp. 1653-1659. (doi: 10.1056/nejmsr2005760) (PMID:32227760)
Cleland, J. G.F. , Lyon, A. R., McDonagh, T. and McMurray, J. J.V. (2020) The year in cardiology: heart failure. European Heart Journal, 41(12), pp. 1232-1248. (doi: 10.1093/eurheartj/ehz949) (PMID:31901936) (PMCID:PMC7084174)
Sharma, A. et al. (2020) Impact of regulatory guidance on evaluating cardiovascular risk of new glucose-lowering therapies to treat type 2 diabetes mellitus. Circulation, 141(10), pp. 843-862. (doi: 10.1161/circulationaha.119.041022) (PMID:31992065)
Docherty, K. F. et al. (2020) Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. European Journal of Heart Failure, 22(3), pp. 528-538. (doi: 10.1002/ejhf.1682) (PMID:31849164)
Kristensen, S. L. and McMurray, J. J.V. (2020) Diagnosing heart failure with preserved ejection fraction – what's the score? European Journal of Heart Failure, 22(3), pp. 425-427. (doi: 10.1002/ejhf.1764) (PMID:32086989)
Lee, M. M.Y. , Petrie, M. C. , McMurray, J. J.V. and Sattar, N. (2020) How do SGLT2 (sodium-glucose cotransporter 2) inhibitors and GLP-1 (glucagon-like peptide-1) receptor agonists reduce cardiovascular outcomes? Arteriosclerosis, Thrombosis, and Vascular Biology, 40(3), pp. 506-522. (doi: 10.1161/atvbaha.119.311904) (PMID:31996025)
Monzo, L. et al. (2020) Visit-to-visit blood pressure variation and outcomes in heart failure with reduced ejection fraction: findings from the Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms trial. Journal of Hypertension, 38(3), pp. 420-425. (doi: 10.1097/HJH.0000000000002275) (PMID:31584516)
Shen, L., Jhund, P. and McMurray, J. (2020) Dyslipidaemia, a factor worthy of adjustment: reply. European Journal of Heart Failure, 22(3), pp. 564-565. (doi: 10.1002/ejhf.1718) (PMID:31919977)
Serenelli, M. et al. (2020) Mineralocorticoid receptor antagonists, blood pressure, and outcomes in heart failure with reduced ejection fraction. JACC: Heart Failure, 8(3), pp. 188-198. (doi: 10.1016/j.jchf.2019.09.011) (PMID:31926854) (PMCID:PMC7086149)
Rorth, R. et al. (2020) Comparison of BNP and NT-proBNP in patients with heart failure and reduced ejection fraction. Circulation: Heart Failure, 13(2), e006541. (doi: 10.1161/CIRCHEARTFAILURE.119.006541) (PMID:32065760)
McMurray, J. J.V. et al. (2020) Effects of Sacubitril-Valsartan, versus Valsartan, in Women Compared to Men with Heart Failure and Preserved Ejection Fraction: Insights from PARAGON-HF. Circulation, 141(5), pp. 338-351. (doi: 10.1161/CIRCULATIONAHA.119.044491) (PMID:31736337)
Solomon, S. D. et al. (2020) Sacubitril/valsartan across the spectrum of ejection fraction in heart failure. Circulation, 141(5), pp. 352-361. (doi: 10.1161/circulationaha.119.044586) (PMID:31736342)
Vaduganathan, M. et al. (2020) Prior heart failure hospitalization, clinical outcomes, and response to sacubitril/valsartan compared with valsartan in HFpEF. Journal of the American College of Cardiology, 75(3), pp. 245-254. (doi: 10.1016/j.jacc.2019.11.003) (PMID:31726194)
Kosiborod, M. N. et al. (2020) Effects of dapagliflozin on symptoms, function and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial. Circulation, 141(2), pp. 90-99. (doi: 10.1161/CIRCULATIONAHA.119.044138) (PMID:31736335) (PMCID:PMC6964869)
Martinez, F. A. et al. (2020) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to age: insights from DAPA-HF. Circulation, 141(2), pp. 100-111. (doi: 10.1161/CIRCULATIONAHA.119.044133) (PMID:31736328)
Shah, S. et al. (2020) Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications, 11, 163. (doi: 10.1038/s41467-019-13690-5) (PMID:31919418) (PMCID:PMC6952380)
Israr, M. Z. et al. (2020) Implications of serial measurements of natriuretic peptides in heart failure: insights from BIOSTAT‐CHF. European Journal of Heart Failure, 22(8), pp. 1486-1490. (doi: 10.1002/ejhf.1951) (PMID:32666670)
2019
Kotecha, D. et al. (2019) Impact of renal impairment on beta-blocker efficacy in patients with heart failure. Journal of the American College of Cardiology, 74(23), pp. 2893-2904. (doi: 10.1016/j.jacc.2019.09.059) (PMID:31806133)
Shah, A. M. et al. (2019) Echocardiographic features of patients with heart failure and preserved left ventricular ejection fraction. Journal of the American College of Cardiology, 74(23), pp. 2858-2873. (doi: 10.1016/j.jacc.2019.09.063) (PMID:31806129)
Dewan, P. et al. (2019) Sex-related differences in heart failure with preserved ejection fraction. Circulation: Heart Failure, 12(12), e006539. (doi: 10.1161/CIRCHEARTFAILURE.119.006539) (PMID:31813280)
Ferreira, J. P., Rossello, X., Eschalier, R., McMurray, J. J.V. , Pocock, S., Girerd, N., Rossignol, P., Pitt, B. and Zannad, F. (2019) MRAs in Elderly HF Patients Individual Patient-Data Meta-Analysis of RALES, EMPAHSIS-HF, and TOPCAT. JACC: Heart Failure, 7(12), pp. 1012-1021. (doi: 10.1016/j.jchf.2019.08.017) (PMID:31779922)
Platz, E., Solomon, S. D. and McMurray, J. J.V. (2019) Lung ultrasound: monitoring congestion in patients with heart failure. European Journal of Heart Failure, 21(12), pp. 1614-1615. (doi: 10.1002/ejhf.1636) (PMID:31702095)
McMurray, J. J.V. et al. (2019) Dapagliflozin in patients with heart failure and reduced ejection fraction. New England Journal of Medicine, 381, pp. 1995-2008. (doi: 10.1056/NEJMoa1911303)
Ferreira, J. P., Rossignol, P., Dewan, P. , Lamiral, Z., White, W. B., Pitt, B., McMurray, J. J.V. and Zannad, F. (2019) Income level and inequality as complement to geographical differences in cardiovascular trials. American Heart Journal, 218, pp. 66-74. (doi: 10.1016/j.ahj.2019.08.019) (PMID:31707330)
Docherty, K. F. and McMurray, J. J.V. (2019) PIONEER-HF: a new frontier in the role of neprilysin inhibition in the management of heart failure with reduced ejection fraction. Cardiovascular Research, 115(13), e136-e139. (doi: 10.1093/cvr/cvz223) (PMID:31497841)
Conrad, N., Judge, A., Canoy, D., Tran, J., Pinho-Gomes, A. C., Millett, E. R.C., Salimi-Khorshidi, G., Cleland, J. G. , McMurray, J. J.V. and Rahimi, K. (2019) Temporal trends and patterns in mortality after incident heart failure: a longitudinal analysis of 86 000 individuals. JAMA Cardiology, 4(11), pp. 1102-1111. (doi: 10.1001/jamacardio.2019.3593) (PMID:31479100) (PMCID:PMC6724155)
McMurray, J. J.V. et al. (2019) The Dapagliflozin and Prevention of Adverse-outcomes in Heart Failure (DAPA-HF) trial: baseline characteristics. European Journal of Heart Failure, 21(11), pp. 1402-1411. (doi: 10.1002/ejhf.1548) (PMID:31309699)
Solomon, S. D. et al. (2019) Angiotensin–neprilysin inhibition in heart failure with preserved ejection fraction. New England Journal of Medicine, 381, pp. 1609-1620. (doi: 10.1056/NEJMoa1908655) (PMID:31475794)
Selvaraj, S. et al. (2019) Prognostic implications of congestion on physical examination among contemporary patients with heart failure and reduced ejection fraction: PARADIGM-HF. Circulation, 140, pp. 1369-1379. (doi: 10.1161/CIRCULATIONAHA.119.039920) (PMID:31510768)
Coiro, S. et al. (2019) Association of diabetes and kidney function according to age and systolic function with the incidence of sudden cardiac death and non-sudden cardiac death in myocardial infarction survivors with heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.1541) (PMID:31476097)
Lee, M. M.Y. , Sattar, N. , McMurray, J. J.V. and Packard, C. J. (2019) Statins in the prevention and treatment of heart failure: a review of the evidence. Current Atherosclerosis Reports, 21(10), 41. (doi: 10.1007/s11883-019-0800-z)
Platz, E. et al. (2019) Lung ultrasound in acute heart failure: prevalence of pulmonary congestion and short- and long-term outcomes. JACC: Heart Failure, 7(10), pp. 849-858. (doi: 10.1016/j.jchf.2019.07.008) (PMID:31582107)
Chandra, A. et al. (2019) Health-related quality of life in heart failure with preserved ejection fraction the PARAGON-HF trial. JACC: Heart Failure, 7(10), pp. 862-874. (doi: 10.1016/j.jchf.2019.05.015) (PMID:31302043)
Yap, J. et al. (2019) Association of diabetes mellitus on cardiac remodeling, quality of life, and clinical outcomes in heart failure with reduced and preserved ejection fraction. Journal of the American Heart Association, 8(17), e013114. (doi: 10.1161/jaha.119.013114) (PMID:31431116)
Beggs, S. A.S. , Rørth, R., Gardner, R. S. and McMurray, J. J.V. (2019) Anticoagulation therapy in heart failure and sinus rhythm: a systematic review and meta-analysis. Heart, 105(17), pp. 1325-1334. (doi: 10.1136/heartjnl-2018-314381) (PMID:30962190)
Ferreira, J. P. et al. (2019) World Heart Federation Roadmap for heart failure. Global Heart, 14(3), pp. 197-214. (doi: 10.1016/j.gheart.2019.07.004) (PMID:31451235)
Grodin, J. L. et al. (2019) Prognostic implications of changes in amino-terminal pro–B-type natriuretic peptide in acute decompensated heart failure: insights from ASCEND-HF. Journal of Cardiac Failure, 25(9), pp. 703-711. (doi: 10.1016/j.cardfail.2019.04.002) (PMID:30953792)
Kristensen, S. L., Rorth, R., Jhund, P. S. , Docherty, K. , Sattar, N. , Preiss, D. , Kober, L., Petrie, M. C. and McMurray, J. J.V. (2019) Cardiovascular, mortality and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet Diabetes and Endocrinology, 7(10), pp. 776-785. (doi: 10.1016/S2213-8587(19)30249-9) (PMID:31422062)
Tromp, J. et al. (2019) Microvascular disease in patients with diabetes with heart failure and reduced ejection versus preserved ejection fraction. Diabetes Care, 42(9), pp. 1792-1799. (doi: 10.2337/dc18-2515) (PMID:31292141)
Gerstein, H. C., McMurray, J. and Holman, R. R. (2019) The importance of randomised vs non-randomised trials - authors' reply. Lancet, 394(10199), p. 635. (doi: 10.1016/S0140-6736(19)31111-0) (PMID:31448734)
McMurray, J. J.V. and Docherty, K. F. (2019) Phosphodiesterase-9 inhibition in heart failure: a further opportunity to augment the effects of natriuretic peptides? Journal of the American College of Cardiology, 74(7), pp. 902-904. (doi: 10.1016/j.jacc.2019.07.008) (PMID:31416534)
Leong, D. P., McMurray, J. J.V. , Joseph, P. G. and Yusuf, S. (2019) From ACE inhibitors/ARBs to ARNIs in coronary artery disease and heart failure (Part 2/5). Journal of the American College of Cardiology, 74(5), pp. 683-698. (doi: 10.1016/j.jacc.2019.04.068) (PMID:31370961)
Tromp, J. et al. (2019) Age-related characteristics and outcomes of patients with heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 74(5), pp. 601-612. (doi: 10.1016/j.jacc.2019.05.052) (PMID:31370950)
Felker, G. M., Borentain, M., Cleland, J. G.F. , DeSouza, M. M., Kessler, P. D., O'Connor, C. M., Seiffert, D., Teerlink, J. R., Voors, A. A. and McMurray, J. J.V. (2019) Rationale and design for the development of a novel nitroxyl donor in patients with acute heart failure. European Journal of Heart Failure, 21(8), pp. 1022-1031. (doi: 10.1002/ejhf.1504) (PMID:31168885)
Rørth, R., Dewan, P. , Kristensen, S. L., Jhund, P. S. , Petrie, M. C. , Køber, L. and McMurray, J. J.V. (2019) Efficacy of an implantable cardioverter-defibrillator in patients with diabetes and heart failure and reduced ejection fraction. Clinical Research in Cardiology, 108(8), pp. 868-877. (doi: 10.1007/s00392-019-01415-z) (PMID:30689020) (PMCID:PMC6652172)
Shen, L. et al. (2019) Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction. European Journal of Heart Failure, 21(8), pp. 974-984. (doi: 10.1002/ejhf.1535) (PMID:31271255) (PMCID:PMC7079555)
Chin, K. L., Collier, T., Pocock, S., Pitt, B., McMurray, J. J.V. , van Veldhuisen, D. J., Swedberg, K., Vincent, J., Zannad, F. and Liew, D. (2019) Impact of eplerenone on major cardiovascular outcomes in patients with systolic heart failure according to baseline heart rate. Clinical Research in Cardiology, 108, pp. 806-814. (doi: 10.1007/s00392-018-1410-4) (PMID:30604047)
Platz, E. et al. (2019) Expert consensus document: Reporting checklist for quantification of pulmonary congestion by lung ultrasound in heart failure. European Journal of Heart Failure, 21(7), pp. 844-851. (doi: 10.1002/ejhf.1499)
Robertson, J., Schaufelberger, M., Lindgren, M., Adiels, M., Schiöler, L., Torén, K., McMurray, J. , Sattar, N. , Åberg, M. and Rosengren, A. (2019) Higher body mass index in adolescence predicts cardiomyopathy risk in midlife: long-term follow-up among Swedish men. Circulation, 140, pp. 117-125. (doi: 10.1161/circulationaha.118.039132) (PMID:31132859) (PMCID:PMC6635044)
Stewart, S., Moholdt, T. T., Burrell, L. M., Sliwa, K., Mocumbi, A. O., McMurray, J. J.V. , Keates, A. K. and Hawley, J. A. (2019) Winter peaks in heart failure: an inevitable or preventable consequence of seasonal vulnerability? Cardiac Failure Review, 5(2), pp. 83-85. (doi: 10.15420/cfr.2018.40.2) (PMID:31179017) (PMCID:PMC6546000)
Dewan, P. , Docherty, K. F. and McMurray, J. J.V. (2019) Sacubitril/valsartan in Asian patients with heart failure with reduced ejection fraction. Korean Circulation Journal, 49(6), pp. 469-484. (doi: 10.4070/kcj.2019.0136) (PMID:31172710) (PMCID:PMC6554586)
Ahmad, F. A., Petrie, M. C. , McMurray, J. J.V. and Lang, N. N. (2019) Personalized medicine and hospitalization for heart failure: if we understand it, we may be successful in treating it. European Journal of Heart Failure, 21(6), pp. 699-702. (doi: 10.1002/ejhf.1463) (PMID:30972879) (PMCID:PMC6618029)
Balmforth, C. et al. (2019) Outcomes and effect of treatment according to etiology in HFrEF: an analysis of PARADIGM-HF. JACC: Heart Failure, 7(6), pp. 457-465. (doi: 10.1016/j.jchf.2019.02.015) (PMID:31078482)
Shah, S. J., Voors, A. A., McMurray, J. J.V. , Kitzman, D. W., Viethen, T., Bomfim Wirtz, A., Huang, E., Pap, A. F. and Solomon, S. D. (2019) Effect of neladenoson bialanate on exercise capacity among patients with heart failure with preserved ejection fraction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321(21), pp. 2101-2112. (doi: 10.1001/jama.2019.6717) (PMID:31162568) (PMCID:PMC6549300)
Simpson, J., Benson, L., Jhund, P.S. , Dahlström, U., McMurray, J.J.V. and Lund, L.H. (2019) "Real world" eligibility for sacubitril/valsartan in unselected heart failure patients: data from the Swedish Heart Failure Registry. Cardiovascular Drugs and Therapy, 33(3), pp. 315-322. (doi: 10.1007/s10557-019-06873-1) (PMID:30903545) (PMCID:PMC6538576)
Verma, S. and McMurray, J. J.V. (2019) The serendipitous story of SGLT2 inhibitors in heart failure: new insights from DECLARE-TIMI 58. Circulation, 139(22), pp. 2537-2541. (doi: 10.1161/circulationaha.119.040514) (PMID:30882236)
Stienen, S., Ferreira, J. P., Vincent, J., Busselen, M., Li, B., McMurray, J. J.V. , Pitt, B., Girerd, N., Rossignol, P. and Zannad, F. (2019) Estimated long-term survival with eplerenone. Journal of the American College of Cardiology, 73(18), pp. 2357-2359. (doi: 10.1016/j.jacc.2019.02.043) (PMID:31072582)
Rossello, X., Ariti, C., Pocock, S. J., Ferreira, J. P., Girerd, N., McMurray, J. J.V. , Van Veldhuisen, D. J., Pitt, B. and Zannad, F. (2019) Impact of mineralocorticoid receptor antagonists on the risk of sudden cardiac death in patients with heart failure and left-ventricular systolic dysfunction: an individual patient-level meta-analysis of three randomized-controlled trials. Clinical Research in Cardiology, 108, pp. 477-486. (doi: 10.1007/s00392-018-1378-0) (PMID:30264282)
Conrad, N. et al. (2019) Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: a cohort study of 93,000 UK patients. PLoS Medicine, 16(5), e1002805. (doi: 10.1371/journal.pmed.1002805) (PMID:31112552) (PMCID:PMC6528949)
Dewan, P. et al. (2019) Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas. European Journal of Heart Failure, 21(5), pp. 577-587. (doi: 10.1002/ejhf.1347) (PMID:30536678) (PMCID:PMC6607486)
Heerspink, H. H.L. et al. (2019) Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial. Lancet, 393(10184), pp. 1937-1947. (doi: 10.1016/S0140-6736(19)30772-X) (PMID:30995972)
McMurray, J. J.V. (2019) Urinalysis: a window to the heart. JACC: Heart Failure, 7(5), pp. 402-403. (doi: 10.1016/j.jchf.2019.04.002)
McMurray, J. J.V. et al. (2019) A trial to evaluate the effect of the sodium–glucose co‐transporter 2 inhibitor dapagliflozin on morbidity and mortality in patients with heart failure and reduced left ventricular ejection fraction (DAPA‐HF). European Journal of Heart Failure, 21(5), pp. 665-675. (doi: 10.1002/ejhf.1432) (PMID:30895697) (PMCID:PMC6607736)
Shen, L. et al. (2019) Prior pacemaker implantation and clinical outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 7(5), pp. 418-427. (doi: 10.1016/j.jchf.2018.12.006) (PMID:30981744)
Docherty, K. F. and McMurray, J. J.V. (2019) Angiotensin receptor-neprilysin inhibitors: a new paradigm in heart failure with reduced ejection fraction. International Journal of Cardiology, 281, pp. 179-185. (doi: 10.1016/j.ijcard.2018.05.124) (PMID:29891240)
Rossello, X., Ferreira, J. P., McMurray, J. J.V. , Aguilar, D., Pfeffer, M. A., Pitt, B., Dickstein, K., Girerd, N., Rossignol, P. and Zannad, F. (2019) Impact of insulin-treated diabetes on cardiovascular outcomes following high-risk myocardial infarction. European Heart Journal: Acute Cardiovascular Care, 8(3), pp. 231-241. (doi: 10.1177/2048872618803701) (PMID:30259764)
Dewan, P. et al. (2019) Income inequality and outcomes in heart failure: a global between-country analysis. JACC: Heart Failure, 7(4), pp. 336-346. (doi: 10.1016/j.jchf.2018.11.005) (PMID:30738981)
Welsh, P. , Papacosta, O., Ramsay, S., Whincup, P., McMurray, J. , Wannamethee, G. and Sattar, N. (2019) High sensitivity troponin T and incident heart failure in older men: British Regional Heart Study. Journal of Cardiac Failure, 25(4), pp. 230-237. (doi: 10.1016/j.cardfail.2018.08.002) (PMID:30103019) (PMCID:PMC7083232)
Myhre, P. L. et al. (2019) B-type natriuretic peptide during treatment with sacubitril/valsartan: the PARADIGM-HF trial. Journal of the American College of Cardiology, 73(11), pp. 1264-1272. (doi: 10.1016/j.jacc.2019.01.018) (PMID:30846338)
Charytan, D. M. et al. (2019) Metformin use and cardiovascular events in patients with type 2 diabetes and chronic kidney disease. Diabetes, Obesity and Metabolism, 21(5), pp. 1199-1208. (doi: 10.1111/dom.13642) (PMID:30672083)
Kristensen, S. L. et al. (2019) N-terminal pro-B-type natriuretic peptide levels for risk prediction in patients with heart failure and preserved ejection fraction according to atrial fibrillation status. Circulation: Heart Failure, 12(3), e005766. (doi: 10.1161/circheartfailure.118.005766) (PMID:30871349)
Loader, J. et al. (2019) Prevalence and profile of "seasonal frequent flyers" with chronic heart disease: analysis of 1598 patients and 4588 patient-years follow-up. International Journal of Cardiology, 279, pp. 126-132. (doi: 10.1016/j.ijcard.2018.12.060) (PMID:30638747)
McCausland, F. R. et al. (2019) Treatment of anemia with darbepoetin prior to dialysis initiation and clinical outcomes: analyses from the Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT). American Journal of Kidney Diseases, 73(3), pp. 309-315. (doi: 10.1053/j.ajkd.2018.10.006) (PMID:30578152)
Vardeny, O. et al. (2019) Reduced loop diuretic use in patients taking sacubitril/valsartan compared with enalapril: the PARADIGM-HF trial. European Journal of Heart Failure, pp. 337-341. (doi: 10.1002/ejhf.1402) (PMID:30741494) (PMCID:PMC6607492)
Zile, M. R. et al. (2019) Effects of sacubitril/valsartan on biomarkers of extracellular matrix regulation in patients with HFrEF. Journal of the American College of Cardiology, 73(7), pp. 795-806. (doi: 10.1016/j.jacc.2018.11.042) (PMID:30784673)
Abraityte, A., Aukrust, P., Kou, L., Anand, I. S., Young, J., McMurray, J. J.V. , van Veldhuisen, D. J., Gullestad, L. and Ueland, T. (2019) T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF. Clinical Research in Cardiology, 108(2), pp. 133-141. (doi: 10.1007/s00392-018-1331-2) (PMID:30051179)
Macdougall, I. C. et al. (2019) Intravenous iron in patients undergoing maintenance hemodialysis. New England Journal of Medicine, 380(5), pp. 447-458. (doi: 10.1056/NEJMoa1810742) (PMID:30365356)
Macdougall, I. C. et al. (2019) Correction: Intravenous iron in patients undergoing maintenance hemodialysis. New England Journal of Medicine, 380(5), p. 502. (doi: 10.1056/NEJMx180044) (PMID:30641026)
Gerstein, H. C., McMurray, J. and Holman, R. R. (2019) Real-world studies no substitute for RCTs in establishing efficacy. Lancet, 393(10168), pp. 210-211. (doi: 10.1016/S0140-6736(18)32840-X) (PMID:30663582)
Claggett, B., Pocock, S., Wei, L. J., Pfeffer, M. A., McMurray, J. J.V. and Solomon, S. D. (2019) Response by Claggett et al to letter regarding article, “Comparison of time-to-first event and recurrent-event methods in randomized clinical trials”. Circulation, 139(3), pp. 422-423. (doi: 10.1161/CIRCULATIONAHA.118.038478) (PMID:30640547)
Dewan, P. et al. (2019) Differential impact of heart failure with reduced ejection fraction on men and women. Journal of the American College of Cardiology, 73(1), pp. 29-40. (doi: 10.1016/j.jacc.2018.09.081) (PMID:30621948)
Lee, M. M. Y. , McMurray, J. J.V. , Lorenzo-Almorós, A., Kristensen, S. L., Sattar, N. , Jhund, P. S. and Petrie, M. C. (2019) Diabetic cardiomyopathy. Heart, 105(4), pp. 337-345. (doi: 10.1136/heartjnl-2016-310342) (PMID:30337334)
Rørth, R. et al. (2019) The prognostic value of troponin T and N‐terminal pro B‐type natriuretic peptide, alone and in combination, in heart failure patients with and without diabetes. European Journal of Heart Failure, 21(1), pp. 40-49. (doi: 10.1002/ejhf.1359) (PMID:30537261) (PMCID:PMC6607514)
Bhatt, D. L. et al. (2019) Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial. Lancet, 394(10204), pp. 1169-1180. (doi: 10.1016/S0140-6736(19)31887-2) (PMID:31484629)
Ferreira, J. P. et al. (2019) Renal function stratified dose comparisons of eplerenone versus placebo in the EMPHASIS‐HF trial. European Journal of Heart Failure, 21(3), pp. 345-351. (doi: 10.1002/ejhf.1400) (PMID:30768732)
Schultheiss, H.-P. et al. (2019) Dilated cardiomyopathy. Nature Reviews Disease Primers, 5, 32. (doi: 10.1038/s41572-019-0084-1) (PMID:31073128)
Stienen, S., Ferreira, J. P., Girerd, N., Duarte, K., Lamiral, Z., McMurray, J. J.V. , Pitt, B., Dickstein, K., Zannad, F. and Rossignol, P. (2019) Mean BMI, visit-to-visit BMI variability and BMI changes during follow-up in patients with acute myocardial infarction with systolic dysfunction and/or heart failure: insights from the High-Risk Myocardial Infarction Initiative. Clinical Research in Cardiology, 108(11), pp. 1215-1225. (doi: 10.1007/s00392-019-01453-7) (PMID:30953180)
2018
Tromp, J. et al. (2018) Heart failure with preserved ejection fraction in the young. Circulation, 138(24), pp. 2763-2773. (doi: 10.1161/CIRCULATIONAHA.118.034720) (PMID:30565987)
Beggs, S. A.S. , Gardner, R. S. and McMurray, J. J.V. (2018) Who benefits from a defibrillator—balancing the risk of sudden versus non-sudden death. Current Heart Failure Reports, 15(6), pp. 376-389. (doi: 10.1007/s11897-018-0416-6) (PMID:30413991) (PMCID:PMC6267371)
Bouabdallaoui, N., Claggett, B., Zile, M. R., McMurray, J. J.V. , O'Meara, E., Packer, M., Prescott, M. F., Swedberg, K., Solomon, S. D. and Rouleau, J. L. (2018) Growth differentiation factor-15 is not modified by sacubitril/valsartan and is an independent marker of risk in patients with heart failure and reduced ejection fraction: the PARADIGM-HF trial. European Journal of Heart Failure, 20(12), pp. 1701-1709. (doi: 10.1002/ejhf.1301) (PMID:30204280)
Campbell, R. T., Petrie, M. C. and McMurray, J. J.V. (2018) Redefining heart failure phenotypes based on ejection fraction. European Journal of Heart Failure, 20(12), pp. 1634-1635. (doi: 10.1002/ejhf.1325) (PMID:30328651)
Campbell, R. T., Petrie, M. C. and McMurray, J. J.V. (2018) Talking to patients with heart failure about end of life. European Journal of Heart Failure, 20(12), pp. 1763-1765. (doi: 10.1002/ejhf.1321) (PMID:30295978) (PMCID:PMC6607510)
Idzerda, N. M.A., Persson, F., Pena, M. J., Brenner, B. M., Brunel, P., Chaturvedi, N., McMurray, J. J. , Parving, H.-H., de Zeeuw, D. and Heerspink, H. J.L. (2018) N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) predicts the cardio‐renal response to aliskiren in patients with type 2 diabetes at high renal and cardiovascular risk. Diabetes, Obesity and Metabolism, 20(12), pp. 2899-2904. (doi: 10.1111/dom.13465) (PMID:29987919) (PMCID:PMC6282705)
Ramires, F. J.A. et al. (2018) Post hoc analyses of SHIFT and PARADIGM-HF highlight the importance of chronic Chagas' cardiomyopathy Comment on: “Safety profile and efficacy of ivabradine in heart failure due to Chagas heart disease: a post hoc analysis of the SHIFT trial” by Bocchi et al. ESC Heart Failure, 5(6), pp. 1069-1071. (doi: 10.1002/ehf2.12355) (PMID:30298996) (PMCID:PMC6300803)
Srivastava, P. K., Claggett, B. L., Solomon, S. D., McMurray, J. J.V. , Packer, M., Zile, M. R., Desai, A. S., Rouleau, J. L., Swedberg, K. and Fonarow, G. C. (2018) Estimated 5-year number needed to treat to prevent cardiovascular death or heart failure hospitalization with angiotensin receptor-neprilysin inhibition vs standard therapy for patients with heart failure with reduced ejection fraction: an analysis of data from the PARADIGM-HF trial. JAMA Cardiology, 3(12), pp. 1226-1231. (doi: 10.1001/jamacardio.2018.3957) (PMID:30484837) (PMCID:PMC6583093)
Fudim, M. et al. (2018) Relation of volume overload to clinical outcomes in acute heart failure (from ASCEND-HF). American Journal of Cardiology, 122(9), pp. 1506-1512. (doi: 10.1016/j.amjcard.2018.07.023) (PMID:30172362) (PMCID:PMC6924269)
Kristensen, S. L., Rørth, R., Jhund, P. S. , Shen, L., Lee, M. M.Y. , Petrie, M. C. , Køber, L. and McMurray, J. J.V. (2018) Microvascular complications in diabetes patients with heart failure and reduced ejection fraction-insights from the Beta-blocker Evaluation of Survival Trial. European Journal of Heart Failure, 20(11), pp. 1549-1556. (doi: 10.1002/ejhf.1201) (PMID:29727039)
Voors, A. A. et al. (2018) Rationale and design of the phase 2b clinical trials to study the effects of the partial adenosine A1-receptor agonist neladenoson bialanate in patients with chronic heart failure with reduced (PANTHEON) and preserved (PANACHE) ejection fraction. European Journal of Heart Failure, 20(11), pp. 1601-16010. (doi: 10.1002/ejhf.1295) (PMID:30225882)
Hernandez, A. F. et al. (2018) Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial. Lancet, 392(10157), pp. 1519-1529. (doi: 10.1016/S0140-6736(18)32261-X) (PMID:30291013)
Haynes, R. et al. (2018) Effects of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: a randomised double-blind trial. Circulation, 138(15), pp. 1505-1514. (doi: 10.1161/CIRCULATIONAHA.118.034818) (PMID:30002098)
Rush, C. J., Campbell, R. T., Jhund, P. S. , Petrie, M. C. and McMurray, J. J.V. (2018) Association is not causation: treatment effects cannot be estimated from observational data in heart failure. European Heart Journal, 39(37), pp. 3417-3438. (doi: 10.1093/eurheartj/ehy407) (PMID:30085087) (PMCID:PMC6166137)
Cosmi, F., Staszewsky, L., McMurray, J. J.V. and Latini, R. (2018) Risk stratification according to insulin type: reply. European Journal of Heart Failure, 20(10), p. 1498. (doi: 10.1002/ejhf.1218) (PMID:29851246)
Januzzi, J. L. et al. (2018) IGFBP7 (insulin-like growth factor–binding protein-7) and neprilysin inhibition in patients with heart failure. Circulation: Heart Failure, 11(10), e005133. (doi: 10.1161/circheartfailure.118.005133) (PMID:30354399)
Campbell, R. T. et al. (2018) Which patients with heart failure should receive specialist palliative care? European Journal of Heart Failure, 20(9), pp. 1338-1347. (doi: 10.1002/ejhf.1240) (PMID:29952090) (PMCID:PMC6607479)
Green, J. B. et al. (2018) Harmony outcomes: a randomized, double-blind, placebo-controlled trial of the effect of albiglutide on major cardiovascular events in patients with type 2 diabetes mellitus-rationale, design, and baseline characteristics. American Heart Journal, 203, pp. 30-38. (doi: 10.1016/j.ahj.2018.03.030) (PMID:30015066)
Ueland, T., Gullestad, L., Kou, L., Aukrust, P., Anand, I. S., Broughton, M. N., McMurray, J. J. , van Veldhuisen, D. J., Warren, D. J. and Bolstad, N. (2018) Pro-gastrin-releasing peptide and outcome in patients with heart failure and anaemia: results from the RED-HF study. ESC Heart Failure, 5(6), pp. 1052-1059. (doi: 10.1002/ehf2.12312) (PMID:30145817) (PMCID:PMC6300802)
Claggett, B., Pocock, S., Wei, L.J., Pfeffer, M. A., McMurray, J. J.V. and Solomon, S. D. (2018) Comparison of time-to-first event and recurrent event methods in randomized clinical trials. Circulation, 138(6), pp. 570-577. (doi: 10.1161/CIRCULATIONAHA.117.033065) (PMID:29588314)
Docherty, K. F. , Jhund, P. S. and McMurray, J. J.V. (2018) Catheter ablation for atrial fibrillation with heart failure. New England Journal of Medicine, 379(5), pp. 491-492. (doi: 10.1056/NEJMc1806519) (PMID:30070094)
Ferreira, J. P., Duarte, K., Pitt, B., Dickstein, K., McMurray, J. J.V. , Zannad, F. and Rossignol, P. (2018) Visit-to-visit blood pressure variation is associated with outcomes in a U-shaped fashion in patients with myocardial infarction complicated with systolic dysfunction and/or heart failure: findings from the EPHESUS and OPTIMAAL trials. Journal of Hypertension, 36(8), pp. 1736-1742. (doi: 10.1097/HJH.0000000000001742) (PMID:29683884)
Grodin, J. L. et al. (2018) Circulating cardiac troponin I levels measured by a novel highly sensitive assay in acute decompensated heart failure: insights from the ASCEND-HF trial. Journal of Cardiac Failure, 24(8), pp. 512-519. (doi: 10.1016/j.cardfail.2018.06.008) (PMID:30012361)
Heerspink, H. J.L. et al. (2018) Baseline characteristics and enrichment results from the SONAR trial. Diabetes, Obesity and Metabolism, 20(8), pp. 1829-1835. (doi: 10.1111/dom.13315) (PMID:29604160)
Lund, L. H. et al. (2018) Heart failure with mid-range ejection fraction in CHARM: characteristics, outcomes and effect of candesartan across the entire ejection fraction spectrum. European Journal of Heart Failure, 20(8), pp. 1230-1239. (doi: 10.1002/ejhf.1149) (PMID:29431256)
Abdul-Rahim, A. H. , Shen, L., Rush, C. J., Jhund, P. S. , Lees, K. R. and McMurray, J. J.V. (2018) Effect of digoxin in patients with heart failure and mid-range (borderline) left ventricular ejection fraction. European Journal of Heart Failure, 20(7), pp. 1139-1145. (doi: 10.1002/ejhf.1160) (PMID:29493058)
Ferreira, J. P., Duarte, K., McMurray, J. J.V. , Pitt, B., van Veldhuisen, D. J., Vincent, J., Ahmad, T., Tromp, J., Rossignol, P. and Zannad, F. (2018) Data-driven approach to identify subgroups of heart failure with reduced ejection fraction patients with different prognoses and aldosterone antagonist response patterns. Circulation: Heart Failure, 11(7), e004926. (doi: 10.1161/CIRCHEARTFAILURE.118.004926) (PMID:29997240)
Packer, M., Claggett, B., Lefkowitz, M. P., McMurray, J. J.V. , Rouleau, J. L., Solomon, S. D. and Zile, M. R. (2018) Effect of neprilysin inhibition on renal function in patients with type 2 diabetes and chronic heart failure who are receiving target doses of inhibitors of the renin-angiotensin system: a secondary analysis of the PARADIGM-HF trial. Lancet Diabetes and Endocrinology, 6(7), pp. 547-554. (doi: 10.1016/S2213-8587(18)30100-1) (PMID:29661699)
Solomon, S. D. et al. (2018) Baseline characteristics of patients with heart failure and preserved ejection fraction in the PARAGON-HF trial. Circulation: Heart Failure, 11(7), e004962. (doi: 10.1161/CIRCHEARTFAILURE.118.004962) (PMID:29980595)
Vaduganathan, M., Claggett, B., Packer, M., McMurray, J. J.V. , Rouleau, J. L., Zile, M. R., Swedberg, K. and Solomon, S. D. (2018) Natriuretic peptides as biomarkers of treatment response in clinical trials of heart failure. JACC: Heart Failure, 6(7), pp. 564-569. (doi: 10.1016/j.jchf.2018.02.007) (PMID:29501807)
McMurray, J. J.V. (2018) Only trials tell the truth about treatment effects. Journal of the American College of Cardiology, 71(23), pp. 2640-2642. (doi: 10.1016/j.jacc.2018.04.019) (PMID:29880123)
Rørth, R., Jhund, P. S. , Mogensen, U. M., Kristensen, S. L., Petrie, M. C. , Køber, L. and McMurray, J. J.V. (2018) Risk of incident heart failure in patients with diabetes and asymptomatic left ventricular systolic dysfunction. Diabetes Care, 41(6), pp. 1285-1291. (doi: 10.2337/dc17-2583) (PMID:29626073)
Chanfra, A. et al. (2018) Effects of sacubitril/valsartan on physical and social activity limitations in patients with heart failure: a secondary analysis of the PARADIGM-HF trial. JAMA Cardiology, 3(6), pp. 498-505. (doi: 10.1001/jamacardio.2018.0398) (PMID:29617523) (PMCID:PMC6128510)
Damman, K. et al. (2018) Renal effects and associated outcomes during angiotensin-neprilysin inhibition in heart failure. JACC: Heart Failure, 6(6), pp. 489-498. (doi: 10.1016/j.jchf.2018.02.004) (PMID:29655829)
Heerspink, H. J.L. et al. (2018) Rationale and protocol of the Study of Diabetic Nephropathy with Atrasentan (SONAR) trial: A clinical trial design novel to diabetic nephropathy. Diabetes, Obesity and Metabolism, 20(6), pp. 1369-1376. (doi: 10.1111/dom.13245) (PMID:29405626)
McMurray, J. J.V. et al. (2018) Cost-effectiveness of sacubitril/valsartan in the treatment of heart failure with reduced ejection fraction. Heart, 104(12), pp. 1006-1013. (doi: 10.1136/heartjnl-2016-310661) (PMID:29269379) (PMCID:PMC5992367)
Simpson, J. and McMurray, J. J.V. (2018) Prognostic modeling in heart failure: time for a reboot. JACC: Heart Failure, 6(6), pp. 463-464. (doi: 10.1016/j.jchf.2018.03.020) (PMID:29852930)
Frikha, Z., Ferreira, J. P., Bozec, E., McMurray, J. J.V. , Pitt, B., Dickstein, K., Rossignol, P., Zannad, F. and Girerd, N. (2018) Relation of high serum bilirubin to short-term mortality following a myocardial infarction complicated by left ventricular systolic dysfunction (from the High-Risk Myocardial Infarction Database Initiative). American Journal of Cardiology, 121(9), pp. 1015-1020. (doi: 10.1016/j.amjcard.2018.01.012) (PMID:29631805)
Cosmi, F. et al. (2018) Treatment with insulin is associated with worse outcome in patients with chronic heart failure and diabetes. European Journal of Heart Failure, 20(5), pp. 888-895. (doi: 10.1002/ejhf.1146) (PMID:29488676)
Lupón, J. et al. (2018) Barcelona Bio-HF Calculator Version 2.0: incorporation of angiotensin II receptor blocker neprilysin inhibitor (ARNI) and risk for heart failure hospitalization. European Journal of Heart Failure, 20(5), pp. 938-940. (doi: 10.1002/ejhf.949) (PMID:28949101)
O'Meara, E., Prescott, M. F., Claggett, B., Rouleau, J. L., Chiang, L.-M., Solomon, S. D., Packer, M., McMurray, J. J.V. and Zile, M. R. (2018) Independent prognostic value of serum soluble ST2 measurements in patients with heart failure and a reduced ejection fraction in the PARADIGM-HF Trial (prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure). Circulation: Heart Failure, 11(5), e004446. (doi: 10.1161/CIRCHEARTFAILURE.117.004446) (PMID:29748349)
Seferović, P. M. et al. (2018) Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 20(5), pp. 853-872. (doi: 10.1002/ejhf.1170) (PMID:29520964)
Theodorakis, M. J. et al. (2018) Baseline characteristics and temporal differences in Acarbose Cardiovascular Evaluation (ACE) trial participants. American Heart Journal, 199, pp. 170-175. (doi: 10.1016/j.ahj.2017.09.001) (PMID:29754657)
McMurray, J. J.V. (2018) Renin–angiotensin system inhibition—it's been a long but fruitful journey. European Journal of Heart Failure, 20(4), pp. 687-688. (doi: 10.1002/ejhf.1155) (PMID:29405513)
Mogensen, U. M. et al. (2018) Effect of sacubitril/valsartan on recurrent events in the prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF). European Journal of Heart Failure, 20(4), pp. 760-768. (doi: 10.1002/ejhf.1139) (PMID:29431251)
Vardeny, O. et al. (2018) Incidence, predictors, and outcomes associated with hypotensive episodes among heart failure patients receiving sacubitril/valsartan or enalapril: the PARADIGM-HF trial (prospective comparison of angiotensin receptor neprilysin inhibitor with angiotensin-converting enzyme inhibitor to determine impact on global mortality and morbidity in heart failure). Circulation: Heart Failure, 11(4), e004745. (doi: 10.1161/CIRCHEARTFAILURE.117.004745) (PMID:29643067)
Tromp, J. et al. (2018) Multimorbidity in patients with heart failure from 11 Asian regions: A prospective cohort study using the ASIAN-HF registry. PLoS Medicine, 15(3), e1002541. (doi: 10.1371/journal.pmed.1002541) (PMID:29584721) (PMCID:PMC5870945)
Bethel, M. A. and McMurray, J. J.V. (2018) Class effect for sodium glucose-cotransporter-2 inhibitors in cardiovascular outcomes: implications for the cardiovascular disease specialist. Circulation, 137(12), pp. 1218-1220. (doi: 10.1161/CIRCULATIONAHA.117.030117) (PMID:29555706)
Hicks, K. A. et al. (2018) 2017 cardiovascular and stroke endpoint definitions for clinical trials. Journal of the American College of Cardiology, 71(9), pp. 1021-1034. (doi: 10.1016/j.jacc.2017.12.048) (PMID:29495982)
Hallow, K. M., Helmlinger, G., Greasley, P. J., McMurray, J. J.V. and Boulton, D. W. (2018) Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis. Diabetes, Obesity and Metabolism, 20(3), pp. 479-487. (doi: 10.1111/dom.13126) (PMID:29024278)
Jorsal, A., Wiggers, H. and McMurray, J. J.V. (2018) Heart failure: epidemiology, pathophysiology, and management of heart failure in diabetes mellitus. Endocrinology and Metabolism Clinics of North America, 47(1), pp. 117-135. (doi: 10.1016/j.ecl.2017.10.007) (PMID:29407047)
Mogensen, U. M. et al. (2018) Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM-HF. European Journal of Heart Failure, 20(3), pp. 514-522. (doi: 10.1002/ejhf.1056) (PMID:29193563)
Seferovic, J. P., Pfeffer, M. A., Claggett, B., Desai, A. S., de Zeeuw, D., Haffner, S. M., McMurray, J. J.V. , Parving, H.-H., Solomon, S. D. and Chaturvedi, N. (2018) Three-question set from Michigan Neuropathy Screening Instrument adds independent prognostic information on cardiovascular outcomes: analysis of ALTITUDE trial. Diabetologia, 61(3), pp. 581-588. (doi: 10.1007/s00125-017-4485-y) (PMID:29098323)
Wolsk, E., Claggett, B., Køber, L., Pocock, S., Yusuf, S., Swedberg, K., McMurray, J. J.V. , Granger, C. B., Pfeffer, M. A. and Solomon, S. D. (2018) Contribution of cardiac and extra-cardiac disease burden to risk of cardiovascular outcomes varies by ejection fraction in heart failure. European Journal of Heart Failure, 20(3), pp. 504-510. (doi: 10.1002/ejhf.1073) (PMID:29193462)
Hicks, K. A. et al. (2018) 2017 cardiovascular and stroke endpoint definitions for clinical trials. Circulation, 137(9), pp. 961-972. (doi: 10.1161/CIRCULATIONAHA.117.033502) (PMID:29483172)
Ferreira, J. P. et al. (2018) Stroke risk in patients with reduced ejection fraction after myocardial infarction without atrial fibrillation. Journal of the American College of Cardiology, 71(7), pp. 727-735. (doi: 10.1016/j.jacc.2017.12.011) (PMID:29447733)
Conrad, N. et al. (2018) Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals. Lancet, 391(10120), pp. 10-16. (doi: 10.1016/S0140-6736(17)32520-5) (PMID:29174292) (PMCID:PMC5814791)
Cotter, G. et al. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20(2), pp. 317-322. (doi: 10.1002/ejhf.889) (PMID:28871621)
Ferreira, J. P., Duarte, K., Pfeffer, M. A., McMurray, J. J.V. , Pitt, B., Dickstein, K., Zannad, F. and Rossignol, P. (2018) Association between mean systolic and diastolic blood pressure throughout the follow-up and cardiovascular events in acute myocardial infarction patients with systolic dysfunction and/or heart failure: an analysis from the High-Risk Myocardial Infarction Database Initiative. European Journal of Heart Failure, 20(2), pp. 323-331. (doi: 10.1002/ejhf.1131) (PMID:29314455)
Platz, E., Jhund, P. S. , Claggett, B. L., Pfeffer, M. A., Swedberg, K., Granger, C. B., Yusuf, S., Solomon, S. D. and McMurray, J. J. (2018) Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. European Journal of Heart Failure, 20(2), pp. 295-303. (doi: 10.1002/ejhf.901) (PMID:28872259)
Rørth, R. et al. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20(2), pp. 240-247. (doi: 10.1002/ejhf.1046) (PMID:29148231)
Schwartz, G. G. et al. (2018) Association of lipoprotein(a) with risk of recurrent ischemic events following acute coronary syndrome. JAMA Cardiology, 3(2), pp. 164-168. (doi: 10.1001/jamacardio.2017.3833) (PMID:29071331) (PMCID:PMC5838593)
van der Meer, P. et al. (2018) Hyporesponsiveness to darbepoetin alfa in patients with heart failure and anemia in the RED-HF study (Reduction of Events by Darbepoetin Alfa in Heart Failure): clinical and prognostic associations. Circulation: Heart Failure, 11(2), e004431. (doi: 10.1161/CIRCHEARTFAILURE.117.004431) (PMID:29367268)
Welsh, P. et al. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20(2), pp. 268-277. (doi: 10.1002/ejhf.988) (PMID:28960777) (PMCID:PMC6607475)
Cleland, J. G.F. et al. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39(1), pp. 26-35. (doi: 10.1093/eurheartj/ehx564) (PMID:29040525)
Masip, J. et al. (2018) Indications and practical approach to non-invasive ventilation in acute heart failure. European Heart Journal, 39(1), pp. 17-25. (doi: 10.1093/eurheartj/ehx580) (PMID:29186485)
Beggs, S. A.S. , Jhund, P. S. , Jackson, C. E., McMurray, J. J.V. and Gardner, R. S. (2018) Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis. Heart, 104(2), pp. 144-150. (doi: 10.1136/heartjnl-2016-310850) (PMID:28986406)
Kristensen, S. L. et al. (2018) Aliskiren alone or in combination with enalapril vs. enalapril among patients with chronic heart failure with and without diabetes: a subgroup analysis from the ATMOSPHERE trial. European Journal of Heart Failure, 20(1), pp. 136-147. (doi: 10.1002/ejhf.896) (PMID:28948656)
McMurray, J. J.V. , Ponikowski, P., Bolli, G. B., Lukashevich, V., Kozlovski, P., Kothny, W., Lewsey, J. D. and Krum, H. (2018) Effects of vildagliptin on ventricular function in patients with type 2 diabetes mellitus and heart failure: a randomized placebo-controlled trial. JACC: Heart Failure, 6(1), pp. 8-17. (doi: 10.1016/j.jchf.2017.08.004) (PMID:29032139)
Rørth, R. et al. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6(1), pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019) (PMID:29226811)
Kraus, W. E., Yates, T., Tuomilehto, J., Sun, J.-L., Thomas, L., McMurray, J. J.V. , Bethel, M. A. and Holman, R. R. (2018) Relationship between baseline physical activity assessed by pedometer count and new-onset diabetes in the NAVIGATOR trial. BMJ Open Diabetes Research and Care, 6, e000523. (doi: 10.1136/bmjdrc-2018-000523) (PMID:30073088) (PMCID:PMC6067333)
Macdougall, I. C. et al. (2018) Randomized trial comparing proactive, high-dose versus reactive, low-dose intravenous iron supplementation in hemodialysis (PIVOTAL): study design and baseline data. American Journal of Nephrology, 48(4), pp. 260-268. (doi: 10.1159/000493551) (PMID:30304714)
McAllister, D. A. et al. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes. Circulation, 138(24), pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986) (PMID:29950404) (PMCID:PMC6287897)
Rørth, R. et al. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795) (PMID:30123004) (PMCID:PMC6080879)
Seferovic, J. P. et al. (2018) Retinopathy, neuropathy, and subsequent cardiovascular events in patients with type 2 diabetes and acute coronary syndrome in the ELIXA: the importance of disease duration. Journal of Diabetes Research, 2018, 1631263. (doi: 10.1155/2018/1631263) (PMID:30648112) (PMCID:PMC6311850)
Verma, S. and McMurray, J. J.V. (2018) SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review. Diabetologia, 61(10), pp. 2108-2117. (doi: 10.1007/s00125-018-4670-7) (PMID:30132036)
2017
Kristensen, S. L., Jhund, P. S. , Lee, M. M.Y. , Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K. and McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31(5-6), pp. 545-549. (doi: 10.1007/s10557-017-6754-x) (PMID:28948430)
Senni, M., McMurray, J. J.V. , Wachter, R., McIntyre, H. F., Anand, I. S., Duino, V., Sarkar, A., Shi, V. and Charney, A. (2017) Impact of systolic blood pressure on the safety and tolerability of initiating and up-titrating sacubitril/valsartan in patients with heart failure and reduced ejection fraction: insights from the TITRATION study. European Journal of Heart Failure, 20(3), pp. 491-500. (doi: 10.1002/ejhf.1054) (PMID:29164797)
Shen, L., Jhund, P. S. and McMurray, J. J.V. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377(18), pp. 1794-1795. (doi: 10.1056/NEJMc1711901) (PMID:29091558)
Holman, R. R. et al. (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5(11), pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1) (PMID:28917545)
McDonald, M. A. et al. (2017) Mind the gap: current challenges and future state of heart failure care. Canadian Journal of Cardiology, 33(11), pp. 1434-1449. (doi: 10.1016/j.cjca.2017.08.023) (PMID:29111107)
Mogensen, U. M. et al. (2017) Type of atrial fibrillation and clinical outcomes in patients with heart failure and reduced ejection fraction. Journal of the American College of Cardiology, 70(20), pp. 2490-2500. (doi: 10.1016/j.jacc.2017.09.027) (PMID:29145948)
Shen, L. et al. (2017) Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy. Circulation: Heart Failure, 10(11), e004361. (doi: 10.1161/CIRCHEARTFAILURE.117.004361) (PMID:29141857)
Stewart, S., Keates, A. K., Redfern, A. and McMurray, J. J.V. (2017) Seasonal variations in cardiovascular disease. Nature Reviews Cardiology, 14(11), pp. 654-664. (doi: 10.1038/nrcardio.2017.76) (PMID:28518176)
Wong, C. M. et al. (2017) Heart failure in young adults is associated with high mortality: a contemporary population-level analysis. Canadian Journal of Cardiology, 33(11), pp. 1472-1477. (doi: 10.1016/j.cjca.2017.05.009) (PMID:28941947)
Wolsk, E. et al. (2017) Increases in natriuretic peptides precede heart failure hospitalization in patients with a recent coronary event and type 2 diabetes mellitus. Circulation, 136(16), pp. 1560-1562. (doi: 10.1161/CIRCULATIONAHA.117.029503) (PMID:29038210)
Charytan, D. M. et al. (2017) ESRD after heart failure, myocardial infarction, or stroke in type 2 diabetic patients with CKD. American Journal of Kidney Diseases, 70(4), pp. 522-531. (doi: 10.1053/j.ajkd.2017.04.018) (PMID:28599901)
Kristensen, S. L. et al. (2017) Prognostic value of N-terminal pro-B-type natriuretic peptide levels in heart failure patients with and without atrial fibrillation. Circulation: Heart Failure, 10(10), e004409. (doi: 10.1161/CIRCHEARTFAILURE.117.004409) (PMID:29018174)
Griffin, E. A. et al. (2017) Cost-effectiveness analysis of natriuretic peptide testing and specialist management in patients with suspected acute heart failure. Value in Health, 20(8), pp. 1025-1033. (doi: 10.1016/j.jval.2017.05.007) (PMID:28964433)
Olivier, A. et al. (2017) Effect of eplerenone in patients with heart failure and reduced ejection fraction: potential effect modification by abdominal obesity: insight from the EMPHASIS-HF trial. European Journal of Heart Failure, 19(9), pp. 1186-1197. (doi: 10.1002/ejhf.792) (PMID:28303624)
Platz, E., Merz, A. A., Jhund, P. S. , Vazir, A., Campbell, R. and McMurray, J. J. (2017) Dynamic changes and prognostic value of pulmonary congestion by lung ultrasound in acute and chronic heart failure: a systematic review. European Journal of Heart Failure, 19(9), pp. 1154-1163. (doi: 10.1002/ejhf.839) (PMID:28557302)
Verma, S., McMurray, J. J.V. and Cherney, D. Z.I. (2017) The metabolodiuretic promise of sodium-dependent glucose cotransporter 2 inhibition: the search for the sweet spot in heart failure. JAMA Cardiology, 2(9), pp. 939-940. (doi: 10.1001/jamacardio.2017.1891) (PMID:28636701)
Baigent, C. et al. (2017) Challenges in conducting clinical trials in nephrology: conclusions from a Kidney Disease-Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International, 92(2), pp. 297-305. (doi: 10.1016/j.kint.2017.04.019) (PMID:28709600)
Lewis, E. F. et al. (2017) Health-related quality of life outcomes in PARADIGM-HF. Circulation: Heart Failure, 10(8), e003430. (doi: 10.1161/CIRCHEARTFAILURE.116.003430) (PMID:28784687)
Shen, L., Jhund, P. S. , Mogensen, U. M., Køber, L., Claggett, B., Rogers, J. K. and McMurray, J. J.V. (2017) A re-examination of the BEST Trial using composite outcomes, including emergency department visits. JACC: Heart Failure, 5(8), pp. 591-599. (doi: 10.1016/j.jchf.2017.04.005) (PMID:28774394)
Shen, L. et al. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377(1), pp. 41-51. (doi: 10.1056/NEJMoa1609758) (PMID:28679089)
Price, S. et al. (2017) Expert consensus document: echocardiography and lung ultrasonography for the assessment and management of acute heart failure. Nature Reviews Cardiology, 14(7), pp. 427-440. (doi: 10.1038/nrcardio.2017.56) (PMID:28447662)
Solomon, S. D. et al. (2017) Angiotensin receptor neprilysin inhibition in heart failure with preserved ejection fraction. JACC: Heart Failure, 5(7), pp. 471-482. (doi: 10.1016/j.jchf.2017.04.013) (PMID:28662936)
MacDonald, T. M. et al. (2017) Randomized trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib: the Standard care vs. Celecoxib Outcome Trial (SCOT). European Heart Journal, 38(23), pp. 1843-1850. (doi: 10.1093/eurheartj/ehw387) (PMID:27705888) (PMCID:PMC5837371)
Cleland, J. G.F. et al. (2017) Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS). European Journal of Heart Failure, 19(6), pp. 739-747. (doi: 10.1002/ejhf.786) (PMID:28296139)
Cowie, M. R. et al. (2017) New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment. European Journal of Heart Failure, 19(6), pp. 718-727. (doi: 10.1002/ejhf.809) (PMID:28345190)
Currie, G. , Bethel, M. A., Holzhauer, B., Haffner, S. M., Holman, R. R. and McMurray, J. J.V. (2017) Effect of valsartan on kidney outcomes in people with impaired glucose tolerance. Diabetes, Obesity and Metabolism, 19(6), pp. 791-799. (doi: 10.1111/dom.12877) (PMID:28093841)
Guimarães, P. O. et al. (2017) Effect of Apixaban on all-cause death in patients with atrial fibrillation: a meta-analysis based on imputed placebo effect. Cardiovascular Drugs and Therapy, 31(3), pp. 295-301. (doi: 10.1007/s10557-017-6728-z) (PMID:28516318)
Mogensen, U. M. et al. (2017) The effects of sacubitril/valsartan on coronary outcomes in PARADIGM-HF. American Heart Journal, 188, pp. 35-41. (doi: 10.1016/j.ahj.2017.02.034) (PMID:28577679)
Rossignol, P. et al. (2017) Impact of eplerenone on cardiovascular outcomes in heart failure patients with hypokalaemia. European Journal of Heart Failure, 19(6), pp. 792-799. (doi: 10.1002/ejhf.688) (PMID:27868385)
Wolsk, E. et al. (2017) Role of b-type natriuretic peptide and n-terminal prohormone BNP as predictors of cardiovascular morbidity and mortality in patients with a recent coronary event and type 2 diabetes mellitus. Journal of the American Heart Association, 6(6), e004743. (doi: 10.1161/JAHA.116.004743) (PMID:28554908)
Packer, M. et al. (2017) Effect of ularitide on cardiovascular mortality in acute heart failure. New England Journal of Medicine, 376(20), pp. 1956-1964. (doi: 10.1056/NEJMoa1601895) (PMID:28402745)
Packer, M. and McMurray, J. J.V. (2017) Importance of endogenous compensatory vasoactive peptides in broadening the effects of inhibitors of the renin-angiotensin system for the treatment of heart failure. Lancet, 389(10081), pp. 1831-1840. (doi: 10.1016/S0140-6736(16)30969-2) (PMID:27919443)
Bethel, M. A. et al. (2017) Updated risk factors should be used to predict development of diabetes. Journal of Diabetes and its Complications, 31(5), pp. 859-863. (doi: 10.1016/j.jdiacomp.2017.02.012) (PMID:28319004)
Cowper, P. A. et al. (2017) Economic analysis of apixaban therapy for patients with atrial fibrillation from a US perspective: results from the ARISTOTLE randomized clinical trial. JAMA Cardiology, 2(5), pp. 525-534. (doi: 10.1001/jamacardio.2017.0065) (PMID:28355434)
Ho, C. Y. et al. (2017) Valsartan for attenuating disease evolution in early sarcomeric hypertrophic cardiomyopathy: the design of the Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) trial. American Heart Journal, 187, pp. 145-155. (doi: 10.1016/j.ahj.2017.02.008) (PMID:28454798) (PMCID:PMC5586211)
Packer, M. et al. (2017) Rationale for and design of the TRUE-AHF trial: the effects of ularitide on the short-term clinical course and long-term mortality of patients with acute heart failure. European Journal of Heart Failure, 19(5), pp. 673-681. (doi: 10.1002/ejhf.698) (PMID:27862700)
Packer, M. et al. (2017) Long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure : primary results of the ENABLE Trials. JACC: Heart Failure, 5(5), pp. 317-326. (doi: 10.1016/j.jchf.2017.02.021) (PMID:28449795)
Seferovic, J. P. et al. (2017) Effect of sacubitril/valsartan versus enalapril on glycaemic control in patients with heart failure and diabetes: a post-hoc analysis from the PARADIGM-HF trial. Lancet Diabetes and Endocrinology, 5(5), pp. 333-340. (doi: 10.1016/S2213-8587(17)30087-6) (PMID:28330649) (PMCID:PMC5534167)
Cannon, J. A., Moffitt, P., Perez-Moreno, A. C., Walters, M. R. , Broomfield, N. M., McMurray, J. J.V. and Quinn, T. J. (2017) Cognitive impairment and heart failure: systematic review and meta-analysis. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2017.04.007) (PMID:28433667)
Böhm, M. et al. (2017) Systolic blood pressure, cardiovascular outcomes and efficacy and safety of sacubitril/valsartan (LCZ696) in patients with chronic heart failure and reduced ejection fraction: results from PARADIGM-HF. European Heart Journal, 38(15), pp. 1132-1143. (doi: 10.1093/eurheartj/ehw570) (PMID:28158398)
Nymo, S. H. et al. (2017) Limited added value of circulating inflammatory biomarkers in chronic heart failure. JACC: Heart Failure, 5(4), pp. 256-264. (doi: 10.1016/j.jchf.2017.01.008) (PMID:28359413)
Abdul-Rahim, A. H. et al. (2017) Risk of stroke in chronic heart failure patients with preserved ejection fraction, but without atrial fibrillation: analysis of the CHARM-Preserved and I-Preserve trials. European Heart Journal, 38(10), pp. 742-750. (doi: 10.1093/eurheartj/ehw509) (PMID:28426886) (PMCID:PMC5460584)
Docherty, K. F. , Campbell, R. T., Jhund, P. , Petrie, M. C. and McMurray, J. J.V. (2017) How robust are clinical trials in heart failure? European Heart Journal, 38(5), pp. 338-345. (doi: 10.1093/eurheartj/ehw427) (PMID:27742808)
Emdin, C. A. et al. (2017) Referral for specialist follow-up and its association with post-discharge mortality among patients with systolic heart failure (from the National Heart Failure Audit for England and Wales). American Journal of Cardiology, 119(3), pp. 440-444. (doi: 10.1016/j.amjcard.2016.10.021) (PMID:27884420) (PMCID:PMC5282396)
Beldhuis, I. E., Streng, K. W., Ter Maaten, J. M., Voors, A. A., van der Meer, P., Rossignol, P., McMurray, J. J.V. and Damman, K. (2017) Renin–angiotensin system inhibition, worsening renal function, and outcome in heart failure patients with reduced and preserved ejection fraction. Circulation: Heart Failure, 10(2), e003588. (doi: 10.1161/CIRCHEARTFAILURE.116.003588) (PMID:28209765)
Ferreira, J. P. et al. (2017) Serum chloride and sodium interplay in patients with acute myocardial infarction and heart failure with reduced ejection fraction. Circulation: Heart Failure, 10(2), e003500. (doi: 10.1161/CIRCHEARTFAILURE.116.003500) (PMID:28159825)
Kitai, T. et al. (2017) Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial. European Journal of Heart Failure, 19(2), pp. 241-249. (doi: 10.1002/ejhf.629) (PMID:27634557)
Mueller, C. et al. (2017) European Society of Cardiology-Acute Cardiovascular Care Association Position paper on acute heart failure: A call for interdisciplinary care. European Heart Journal: Acute Cardiovascular Care, 6(1), pp. 81-86. (doi: 10.1177/2048872615593279) (PMID:26124458)
Paton, D. M., Shamy, M., Fedyk, M., Pfeffer, M. A. and McMurray, J. J.V. (2017) Clinical trials involving hypertension [Correspondence]. New England Journal of Medicine, 376(3), pp. 289-290. (doi: 10.1056/NEJMc1615364) (PMID:28099831)
Agewall, S. et al. (2017) 2016 ESC guidelines for the diagnosis and treatment of atrial fibrillation developed in collaboration with the EACTS [Guía ESC 2016 sobre el diagnóstico y tratamiento de la fibrilación auricular, desarrollada en colaboración con la EACTS]. Revista Española de Cardiología, 70(1), 50.e1-50.e84. (doi: 10.1016/j.recesp.2016.11.014)
Hawkins, N. M., Khosla, A., Virani, S. A., McMurray, J. J.V. and FitzGerald, J. M. (2017) B-type natriuretic peptides in chronic obstructive pulmonary disease: a systematic review. BMC Pulmonary Medicine, 17, 11. (doi: 10.1186/s12890-016-0345-7) (PMID:28073350) (PMCID:PMC5223538)
Cannon, J. A. et al. (2017) Dementia-related adverse events in PARADIGM-HF and other trials in heart failure with reduced ejection fraction. European Journal of Heart Failure, 19(1), pp. 129-137. (doi: 10.1002/ejhf.687) (PMID:27868321) (PMCID:PMC5248626)
Burnett, H., Earley, A., Voors, A. A., Senni, M., McMurray, J. J.V. , Deschaseaux, C. and Cope, S. (2017) Thirty years of evidence on the efficacy of drug treatments for chronic heart failure with reduced ejection fraction: a network meta-analysis. Circulation: Heart Failure, 10, e003529. (doi: 10.1161/CIRCHEARTFAILURE.116.003529) (PMID:28087688)
Desai, A. S. et al. (2017) Reduced risk of hyperkalemia during treatment of heart failure with mineralocorticoid receptor antagonists by use of Sacubitril/Valsartan compared with Enalapril: A secondary analysis of the PARADIGM-HF Trial. JAMA Cardiology, 2(1), pp. 79-85. (doi: 10.1001/jamacardio.2016.4733) (PMID:27842179)
Gandhi, P. U. et al. (2017) Prognostic value of insulin-like growth factor-binding protein 7 in patients with heart failure and preserved ejection fraction. Journal of Cardiac Failure, 23(1), pp. 20-28. (doi: 10.1016/j.cardfail.2016.06.006) (PMID:27317843)
Kristensen, S. L. et al. (2017) Clinical and echocardiographic characteristics and cardiovascular outcomes according to diabetes status in patients with heart failure and preserved ejection fraction. A report from the Irbesartan in Heart Failure with Preserved Ejection Fraction Trial (I-Preserve). Circulation, 135(8), pp. 724-735. (doi: 10.1161/CIRCULATIONAHA.116.024593) (PMID:28052977)
Arain, F., Gullestad, L., Nymo, S., Kjekshus, J., Cleland, J. G.F. , Michelsen, A., McMurray, J. J.V. , Wikstrand, J., Aukrust, P. and Ueland, T. (2017) Low YKL-40 in Chronic Heart Failure may predict beneficial effects of statins: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). Biomarkers, 22, pp. 261-267. (doi: 10.1080/1354750X.2016.1204003) (PMID:27325138)
Harumi Higuchi dos Santos, M., Sharma, A., Sun, J.‐L., Pieper, K., McMurray, J. J.V. , Holman, R. R. and Lopes, R. D. (2017) International variation in outcomes among people with cardiovascular disease or cardiovascular risk factors and impaired glucose tolerance: insights from the NAVIGATOR Trial. Journal of the American Heart Association, 6(1), e003892. (doi: 10.1161/JAHA.116.003892) (PMID:28087508) (PMCID:PMC5523624)
Mc Causland, F. R. et al. (2017) Change in hemoglobin trajectory and darbepoetin dose approaching end-stage renal disease: data from the trial to reduce cardiovascular events with aranesp therapy trial. American Journal of Nephrology, 46(6), pp. 488-497. (doi: 10.1159/000485326) (PMID:29241199)
Miro, Ò. et al. (2017) European Society of Cardiology - Acute Cardiovascular Care Association position paper on safe discharge of acute heart failure patients from the emergency department. European Heart Journal: Acute Cardiovascular Care, 6(4), pp. 311-320. (doi: 10.1177/2048872616633853) (PMID:26900163)
Pitts, R. et al. (2017) Aldosterone does not predict cardiovascular events following acute coronary syndrome in patients initially without heart failure. Journal of the American Heart Association, 6(1), e004119. (doi: 10.1161/JAHA.116.004119) (PMID:28073769) (PMCID:PMC5523625)
Ridker, P. M. et al. (2017) Cardiovascular efficacy and safety of Bococizumab in high-risk patients. New England Journal of Medicine, 376(16), pp. 1527-1539. (doi: 10.1056/NEJMoa1701488) (PMID:28304242)
2016
Khder, Y., Shi, V., McMurray, J. J.V. and Lefkowitz, M. P. (2016) Sacubitril/valsartan (LCZ696) in heart failure. In: Handbook of Experimental Pharmacology. Springer. (doi: 10.1007/164_2016_77)
Teerlink, J. R. et al. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388(10062), pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)
Zile, M. R. et al. (2016) Prognostic implications of changes in N-terminal pro-B-type natriuretic peptide in patients with heart failure. Journal of the American College of Cardiology, 68(22), pp. 2425-2436. (doi: 10.1016/j.jacc.2016.09.931) (PMID:27908347)
Damman, K., Solomon, S. D., Pfeffer, M. A., Swedberg, K., Yusuf, S., Young, J. B., Rouleau, J. L., Granger, C. B. and McMurray, J. J.V. (2016) Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme. European Journal of Heart Failure, 18(12), pp. 1508-1517. (doi: 10.1002/ejhf.609) (PMID:27427441)
Mc Causland, F. R. et al. (2016) C-Reactive protein and risk of ESRD: results from the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). American Journal of Kidney Diseases, 68(6), pp. 873-881. (doi: 10.1053/j.ajkd.2016.07.022) (PMID:27646425) (PMCID:PMC5123931)
Pitts, R. et al. (2016) Treatment with Dalcetrapib modifies the relationship between high-density lipoprotein cholesterol and C-reactive protein. Journal of the American College of Cardiology, 68(22), pp. 2488-2490. (doi: 10.1016/j.jacc.2016.09.932) (PMID:27908356)
Ponikowski, P. et al. (2016) 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure [Guía ESC 2016 sobre el diagnóstico y tratamiento de la insuficiencia cardiaca aguda y crónica]. Revista Española de Cardiología, 69(12), 1167.e1-1167.e85. (doi: 10.1016/j.recesp.2016.10.014)
Ferreira, J. P. et al. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, 181. (doi: 10.1186/s12916-016-0731-2) (PMID:27829460) (PMCID:PMC5103492)
Pfeffer, M. A. and McMurray, J. J.V. (2016) Lessons in uncertainty and humility — Clinical trials involving hypertension. New England Journal of Medicine, 375(18), pp. 1756-1766. (doi: 10.1056/NEJMra1510067) (PMID:27806228)
Martín-Sánchez, F. J. et al. (2016) Practical approach on frail older patients attended for acute heart failure. International Journal of Cardiology, 222, pp. 62-71. (doi: 10.1016/j.ijcard.2016.07.151) (PMID:27458825)
Kirchhof, P. et al. (2016) 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Europace, 18(11), pp. 1609-1678. (doi: 10.1093/europace/euw295) (PMID:27567465)
Savarese, G., Giugliano, R. P., Rosano, G. M.C., McMurray, J. , Magnani, G., Filippatos, G., Dellegrottaglie, S., Lund, L. H., Trimarco, B. and Perrone-Filardi, P. (2016) Efficacy and safety of novel oral anticoagulants in patients with atrial fibrillation and heart failure: a meta-analysis. JACC: Heart Failure, 4(11), pp. 881-884. (doi: 10.1016/j.jchf.2016.07.012) (PMID:27614940)
Rørth, R. et al. (2016) Return to the workforce following first hospitalization for heart failure: a Danish nationwide cohort study. Circulation, 134(14), pp. 999-1009. (doi: 10.1161/CIRCULATIONAHA.116.021859) (PMID:27507406)
Cotter, G. et al. (2016) Predictors and associations with outcomes of length of hospital stay in patients with acute heart failure: results from VERITAS. Journal of Cardiac Failure, 22(10), pp. 815-822. (doi: 10.1016/j.cardfail.2015.12.017) (PMID:26721775)
Solomon, S. D., Claggett, B., McMurray, J. J.V. , Hernandez, A. F. and Fonarow, G. C. (2016) Combined neprilysin and renin-angiotensin system inhibition in heart failure with reduced ejection fraction: a meta-analysis. European Journal of Heart Failure, 18(10), pp. 1238-1243. (doi: 10.1002/ejhf.603) (PMID:27364182)
Solomon, S. D., Claggett, B., Packer, M., Desai, A., Zile, M. R., Swedberg, K., Rouleau, J., Shi, V., Lefkowitz, M. and McMurray, J. J.V. (2016) Efficacy of sacubitril/valsartan relative to a prior decompensation: the PARADIGM-HF trial. JACC: Heart Failure, 4(10), pp. 816-822. (doi: 10.1016/j.jchf.2016.05.002) (PMID:27395349)
Vardeny, O. et al. (2016) Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM-HF trial. European Journal of Heart Failure, 18(10), pp. 1228-1234. (doi: 10.1002/ejhf.580) (PMID:27283779) (PMCID:PMC5095784)
McMurray, J. J.V. (2016) The ICD in heart failure - time for a rethink? New England Journal of Medicine, 375(13), pp. 1283-1284. (doi: 10.1056/NEJMe1609826) (PMID:27571386)
Judge, P.K. et al. (2016) Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III—rationale, trial design and baseline data. Nephrology Dialysis Transplantation, (doi: 10.1093/ndt/gfw321) (PMID:27646835)
McMurray, J. J.V. (2016) Site selection and performance in clinical trials. Circulation: Heart Failure, 9(9), e003490. (doi: 10.1161/CIRCHEARTFAILURE.116.003490) (PMID:27623771)
Chin, K. L. et al. (2016) Aspirin does not reduce the clinical benefits of the mineralocorticoid receptor antagonist eplerenone in patients with systolic heart failure and mild symptoms: an analysis of the EMPHASIS-HF study. European Journal of Heart Failure, 18(9), pp. 1175-1181. (doi: 10.1002/ejhf.485) (PMID:26833642)
Gaziano, T. A., Fonarow, G. C., Claggett, B., Chan, W. W., Deschaseaux-Voinet, C., Turner, S. J., Rouleau, J. L., Zile, M. R., McMurray, J. J.V. and Solomon, S. D. (2016) Cost-effectiveness analysis of sacubitril/valsartan vs enalapril in patients with heart failure and reduced ejection fraction. JAMA Cardiology, 1(6), pp. 666-672. (doi: 10.1001/jamacardio.2016.1747) (PMID:27438344)
Hawkins, N. M. et al. (2016) Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment. European Journal of Heart Failure, 18(9), pp. 1162-1171. (doi: 10.1002/ejhf.614) (PMID:27594177)
Jhund, P. S. and McMurray, J. J.V. (2016) The neprilysin pathway in heart failure: a review and guide on the use of sacubitril/valsartan. Heart, 102(17), pp. 1342-1347. (doi: 10.1136/heartjnl-2014-306775) (PMID:27207980) (PMCID:PMC5013095)
Okumura, N. et al. (2016) Effects of sacubitril/valsartan in the PARADIGM-HF Trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) according to background therapy. Circulation: Heart Failure, 9(9), e003212. (doi: 10.1161/CIRCHEARTFAILURE.116.003212) (PMID:27618854)
Senni, M. et al. (2016) Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens. European Journal of Heart Failure, 18(9), pp. 1193-1202. (doi: 10.1002/ejhf.548) (PMID:27170530) (PMCID:PMC5084812)
McMurray, J. J.V. , Dickstein, K. and Kober, L. V. (2016) The author's reply - Aliskiren, Enalapril, or both in heart failure. New England Journal of Medicine, 375(7), pp. 701-702. (doi: 10.1056/NEJMc1606625) (PMID:27532843)
Hawkins, N. M., Virani, S. A., Sperrin, M., Buchan, I. E., McMurray, J. J.V. and Krahn, A. D. (2016) Predicting heart failure decompensation using cardiac implantable electronic devices: a review of practices and challenges. European Journal of Heart Failure, 18(8), pp. 977-986. (doi: 10.1002/ejhf.458) (PMID:26663507)
Cannon, J. A., Shen, L., Jhund, P. , Anand, I. S., Komajda, M., McKelvie, R. S., Zile, M. R., Carson, P. E. and McMurray, J. J. V. (2016) Clinical outcomes according to QRS duration and morphology in the irbesartan in patients with heart failure and preserved systolic function (I-Preserve) trial. European Journal of Heart Failure, 18(8), pp. 1021-1031. (doi: 10.1002/ejhf.547) (PMID:27194023)
Ponikowski, P. et al. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Journal of Heart Failure, 18(8), pp. 891-975. (doi: 10.1002/ejhf.592) (PMID:27207191)
Desai, A. S. et al. (2016) Influence of Sacubitril/Valsartan (LCZ696) on 30-day readmission after heart failure hospitalization. Journal of the American College of Cardiology, 68(3), pp. 241-248. (doi: 10.1016/j.jacc.2016.04.047) (PMID:27417000)
McMurray, J. J.V. and Køber, L. V. (2016) End of the road for vagus nerve stimulation? Journal of the American College of Cardiology, 68(2), pp. 159-160. (doi: 10.1016/j.jacc.2016.05.025) (PMID:27386768)
Sattar, N. , McLaren, J., Kristensen, S. L., Preiss, D. and McMurray, J. J.V. (2016) SGLT2 and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms? Diabetologia, 59(7), pp. 1333-1339. (doi: 10.1007/s00125-016-3956-x) (PMID:27112340) (PMCID:PMC4901113)
Sattar, N. , McLaren, J., Kristensen, S. L., Preiss, D. and McMurray, J. J. (2016) Erratum to: SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms? Diabetologia, 59(7), pp. 1573-1574. (doi: 10.1007/s00125-016-3987-3) (PMID:27174369) (PMCID:PMC4969788)
Okumura, N. et al. (2016) Importance of clinical worsening of heart failure treated in the outpatient setting: evidence from the Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial (PARADIGM-HF). Circulation, 133(23), pp. 2254-2262. (doi: 10.1161/CIRCULATIONAHA.115.020729) (PMID:27143684)
Woodcock, J., Ware, J. H., Miller, P. W., McMurray, J. J.V. , Harrington, D. P. and Drazen, J. M. (2016) Clinical Trials Series. New England Journal of Medicine, 374(22), p. 2167. (doi: 10.1056/NEJMe1601510)
Berry, C. et al. (2016) Prognostic significance of anaemia in patients with heart failure with preserved and reduced ejection fraction: results from the MAGGIC individual patient data meta-analysis. QJM: An International Journal of Medicine, 109(6), pp. 377-382. (doi: 10.1093/qjmed/hcv087) (PMID:25979270)
Metra, M. et al. (2016) Geographic differences in patients in a global acute heart failure clinical trial (from the ASCEND-HF Trial). American Journal of Cardiology, 117(11), pp. 1771-1778. (doi: 10.1016/j.amjcard.2016.03.002) (PMID:27108685)
Abdul-Rahim, A. H. et al. (2016) Effect of single and dual renin-angiotensin blockade on stroke in patients with and without diabetes in VALIANT. European Stroke Journal, 1(2), pp. 93-100. (doi: 10.1177/2396987316646025)
Anker, S. D. et al. (2016) Erratum to “Traditional and new composite endpoints in heart failure clinical trials: facilitating comprehensive efficacy assessments and improving trial efficiency” [Eur J Heart Fail 2016;18:482-489]. European Journal of Heart Failure, 18(6), p. 727. (doi: 10.1002/ejhf.591) (PMID:27324688)
Desai, A. S., Solomon, S., Claggett, B., McMurray, J. J.V. , Rouleau, J., Swedberg, K., Zile, M., Lefkowitz, M., Shi, V. and Packer, M. (2016) Factors associated with noncompletion during the run-in period before randomization and influence on the estimated benefit of LCZ696 in the PARADIGM-HF trial. Circulation: Heart Failure, 9(6), e002735. (doi: 10.1161/CIRCHEARTFAILURE.115.002735) (PMID:27296397)
Lopes, R. D., Pieper, K. S., Stevens, S. R., Solomon, S. D., McMurray, J. J.V. , Pfeffer, M. A., Leimberger, J. D. and Velazquez, E. J. (2016) Predicting outcomes over time in patients with heart failure, left ventricular systolic dysfunction, or both following acute myocardial infarction. Journal of the American Heart Association, 5(6), e003045. (doi: 10.1161/JAHA.115.003045) (PMID:27353607) (PMCID:PMC4937254)
Whellan, D. J., Stebbins, A., Hernandez, A. F., Ezekowitz, J. A., McMurray, J. J.V. , Mather, P. J., Hasselblad, V. and O'Connor, C. M. (2016) Dichotomous relationship between age and 30-day death or rehospitalization in heart failure patients admitted with acute decompensated heart failure: results from the ASCEND-HF trial. Journal of Cardiac Failure, 22(6), pp. 409-416. (doi: 10.1016/j.cardfail.2016.02.011) (PMID:26952241)
McMurray, J. J.V. (2016) Disease management programs in cardiology. Circulation, 133(19), pp. 1836-1837. (doi: 10.1161/circulationaha.116.022480) (PMID:27083508)
Anker, S. D. et al. (2016) Traditional and new composite endpoints in heart failure clinical trials: facilitating comprehensive efficacy assessments and improving trial efficiency. European Journal of Heart Failure, 18(5), pp. 482-489. (doi: 10.1002/ejhf.516) (PMID:27071916)
Campbell, R. T., Willox, G. P., Jhund, P. S. , Hawkins, N. M., Huang, F., Petrie, M. C. and McMurray, J. J. V. (2016) Reporting of lost to follow-up and treatment discontinuation in device and pharmacotherapy trials in chronic heart failure: a systematic review. Circulation: Heart Failure, 9(5), e002842. (doi: 10.1161/CIRCHEARTFAILURE.115.002842) (PMID:27162229)
McMurray, J. J.V. et al. (2016) Aliskiren, enalapril, or aliskiren and enalapril in heart failure. New England Journal of Medicine, 374(16), pp. 1521-1532. (doi: 10.1056/NEJMoa1514859) (PMID:27043774)
Abdul-Rahim, A. H. , MacIsaac, R. L., Jhund, P. S. , Petrie, M. C. , Lees, K. R. and McMurray, J. J.V. (2016) Efficacy and safety of digoxin in patients with heart failure and reduced ejection fraction according to diabetes status: An analysis of the Digitalis Investigation Group (DIG) trial. International Journal of Cardiology, 209, pp. 310-316. (doi: 10.1016/j.ijcard.2016.02.074) (PMID:26913372)
Heerspink, H. J.L. et al. (2016) Renal outcomes with aliskiren in patients with type 2 diabetes: a prespecified secondary analysis of the ALTITUDE randomised controlled trial. Lancet Diabetes and Endocrinology, 4(4), pp. 309-317. (doi: 10.1016/S2213-8587(15)00469-6) (PMID:26774608)
McMurray, J. J.V. and Køber, L. (2016) Trials and the ‘real world’ - how different are they? European Journal of Heart Failure, 18(4), pp. 411-413. (doi: 10.1002/ejhf.503) (PMID:27019978)
Sabe, M. A. et al. (2016) Coronary artery disease is a predictor of progression to dialysis in patients with chronic kidney disease, type 2 diabetes mellitus, and anemia: an analysis of the trial to reduce cardiovascular events with aranesp therapy (TREAT). Journal of the American Heart Association, 5(4), e002850. (doi: 10.1161/JAHA.115.002850) (PMID:27108247) (PMCID:PMC4859277)
Samsky, M. D. et al. (2016) Liver function tests in patients with acute heart failure and associated outcomes: insights from ASCEND-HF. European Journal of Heart Failure, 18(4), pp. 424-432. (doi: 10.1002/ejhf.440) (PMID:26707029)
Teerlink, J. R. et al. (2016) Acute treatment with omecamtiv mecarbil to increase contractility in acute heart failure. Journal of the American College of Cardiology, 67(12), pp. 1444-1455. (doi: 10.1016/j.jacc.2016.01.031) (PMID:27012405)
Ambrosy, A. P. et al. (2016) The clinical course of health status and association with outcomes in patients hospitalized for heart failure: insights from ASCEND-HF. European Journal of Heart Failure, 18(3), pp. 306-313. (doi: 10.1002/ejhf.420) (PMID:26467269)
Damman, K., Kjekshus, J., Wikstrand, J., Cleland, J. G.F. , Komajda, M., Wedel, H., Waagstein, F. and McMurray, J. J.V. (2016) Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction. European Journal of Heart Failure, 18(3), pp. 328-336. (doi: 10.1002/ejhf.462) (PMID:26693947)
Perez, A. L. et al. (2016) Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy. European Journal of Heart Failure, 18(3), pp. 290-297. (doi: 10.1002/ejhf.456) (PMID:26663359)
Solomon, S. D. et al. (2016) Influence of ejection fraction on outcomes and efficacy of sacubitril/valsartan (lcz696) in heart failure with reduced ejection fraction: the prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure (PARADIGM-HF) trial. Circulation: Heart Failure, 9(3), e002744. (doi: 10.1161/CIRCHEARTFAILURE.115.002744) (PMID:26915374)
Heerspink, H.J.L. et al. (2016) Is a reduction in albuminuria associated with renal and cardiovascular protection? A post-hoc analysis of the ALTITUDE trial. Diabetes, Obesity and Metabolism, 18(2), pp. 169-177. (doi: 10.1111/dom.12600) (PMID:26511599)
Vardeny, O. et al. (2016) Influenza vaccination in patients with chronic heart failure: The PARADIGM-HF Trial. JACC: Heart Failure, 4(2), pp. 152-158. (doi: 10.1016/j.jchf.2015.10.012) (PMID:26746371)
Kristensen, S. L. et al. (2016) Risk related to pre–diabetes mellitus and diabetes mellitus in heart failure with reduced ejection fraction: insights from prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial. Circulation: Heart Failure, 9(1), e002560. (doi: 10.1161/CIRCHEARTFAILURE.115.002560) (PMID:26754626) (PMCID:PMC4718182)
McMurray, J. (2016) EMPA-REG – the “diuretic hypothesis”. Journal of Diabetes and its Complications, 30(1), pp. 3-4. (doi: 10.1016/j.jdiacomp.2015.10.012) (PMID:26597600)
Tang, W.H. W. et al. (2016) Prognostic value of baseline and changes in circulating soluble ST2 levels and the effects of nesiritide in acute decompensated heart failure. JACC: Heart Failure, 4(1), pp. 68-77. (doi: 10.1016/j.jchf.2015.07.015) (PMID:26656144)
Theilade, S., Claggett, B., Hansen, T.W., Skali, H., Lewis, E.F., Solomon, S.D., Parving, H.-H., Pfeffer, M., McMurray, J.J. and Rossing, P. (2016) Pulse pressure is not an independent predictor of outcome in type 2 diabetes patients with chronic kidney disease and anemia-the Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT). Journal of Human Hypertension, 30(1), pp. 46-52. (doi: 10.1038/jhh.2015.22) (PMID:25810068)
Zile, M. R. et al. (2016) Plasma biomarkers reflecting profibrotic processes in heart failure with a preserved ejection fraction. Circulation: Heart Failure, 9(1), e002551. (doi: 10.1161/circheartfailure.115.002551) (PMID:26754625)
Emdin, C. A. et al. (2016) Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales. Heart, 103(1), pp. 55-62. (doi: 10.1136/heartjnl-2016-309706) (PMID:27530132)
Jackson, C. E. et al. (2016) The incremental prognostic and clinical value of multiple novel biomarkers in heart failure. European Journal of Heart Failure, 18(12), pp. 1491-1498. (doi: 10.1002/ejhf.543) (PMID:27114189)
Kirchhof, P. et al. (2016) 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European Journal of Cardio-Thoracic Surgery, 50(5), e1-e88. (doi: 10.1093/ejcts/ezw313) (PMID:27663299)
Kirchhof, P. et al. (2016) 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European Heart Journal, 37(38), pp. 2893-2962. (doi: 10.1093/eurheartj/ehw210) (PMID:27567408)
Kristensen, S. L. et al. (2016) Geographic variations in the PARADIGM-HF heart failure trial. European Heart Journal, 37(41), pp. 3167-3174. (doi: 10.1093/eurheartj/ehw226) (PMID:27354044) (PMCID:PMC5106574)
Nadruz, W. et al. (2016) Impact of Body Mass Index on the Accuracy of N-Terminal Pro-Brain Natriuretic Peptide and Brain Natriuretic Peptide for Predicting Outcomes in Patients With Chronic Heart Failure and Reduced Ejection Fraction: Insights From the PARADIGM-HF Study (Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial). Circulation, 134(22), pp. 1785-1787. (doi: 10.1161/CIRCULATIONAHA.116.024976) (PMID:27895026)
Ponikowski, P. et al. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 37(27), pp. 2129-2200. (doi: 10.1093/eurheartj/ehw128) (PMID:27206819)
2015
Cannon, J. A., McKean, A. R., Jhund, P. S. and McMurray, J. J.V. (2015) What can we learn from RELAX-AHF compared to previous AHF trials and what does the future hold? Open Heart, 2(1), e000283. (doi: 10.1136/openhrt-2015-000283) (PMID:26719808) (PMCID:PMC4692046)
Pocock, S. J., McMurray, J. J.V. and Collier, T. J. (2015) Statistical controversies in reporting of clinical trials: part 2 of a 4-part series on statistics for clinical trials. Journal of the American College of Cardiology, 66(23), pp. 2648-62. (doi: 10.1016/j.jacc.2015.10.023) (PMID:26670066)
Pocock, S. J., McMurray, J. J.V. and Collier, T. J. (2015) Making sense of statistics in clinical trial reports: Part 1 of a 4-part series on statistics for clinical trials. Journal of the American College of Cardiology, 66(22), pp. 2536-2549. (doi: 10.1016/j.jacc.2015.10.014) (PMID:26653629)
Claggett, B., Packer, M., McMurray, J. J.V. , Swedberg, K., Rouleau, J., Zile, M. R., Jhund, P., Lefkowitz, M., Shi, V. and Solomon, S. D. (2015) Estimating the long-term treatment benefits of Sacubitril–Valsartan. New England Journal of Medicine, 373(23), pp. 2289-2290. (doi: 10.1056/NEJMc1509753) (PMID:26630151)
Gheorghiade, M. et al. (2015) Effect of vericiguat, a soluble guanylate cyclase stimulator, on natriuretic peptide levels in patients with worsening chronic heart failure and reduced ejection fraction. JAMA: Journal of the American Medical Association, 314(21), pp. 2251-2262. (doi: 10.1001/jama.2015.15734) (PMID:26547357)
McMurray, J. J.J.V. (2015) Improving outcomes in heart failure: a personal perspective. European Heart Journal, 36(48), pp. 3467-3470. (doi: 10.1093/eurheartj/ehv565) (PMID:26578200)
Pfeffer, M. A. et al. (2015) Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. New England Journal of Medicine, 373(23), pp. 2247-2257. (doi: 10.1056/NEJMoa1509225) (PMID:26630143)
Simpson, J. et al. (2015) Comparing LCZ696 with Enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores. Journal of the American College of Cardiology, 66(19), pp. 2059-2071. (doi: 10.1016/j.jacc.2015.08.878) (PMID:26541915)
McMurray, J.J. et al. (2015) A new cost-effectiveness modelling approach in chronic heart failure with reduced ejection fraction - PCV118. Value in Health, 18(7), A394. (doi: 10.1016/j.jval.2015.09.887) (PMID:26532224)
Wang, N. et al. (2015) Regional cardiac dysfunction and outcome in patients with left ventricular dysfunction, heart failure, or both after myocardial infarction. European Heart Journal, (doi: 10.1093/eurheartj/ehv558) (PMID:26530103)
Bello, N. A. et al. (2015) Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease. European Journal of Heart Failure, 17(11), pp. 1201-1207. (doi: 10.1002/ejhf.412) (PMID:26423928) (PMCID:PMC4703474)
Simpson, J. et al. (2015) Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis. European Journal of Heart Failure, 17(11), pp. 1182-1191. (doi: 10.1002/ejhf.346) (PMID:26358762)
Jhund, P. et al. (2015) Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF. European Heart Journal, 36(38), pp. 2576-2584. (doi: 10.1093/eurheartj/ehv330) (PMID:26231885) (PMCID:PMC4595742)
Grodin, J. L. et al. (2015) Circulating kidney injury molecule-1 levels in acute heart failure. JACC: Heart Failure, 3(10), pp. 777-785. (doi: 10.1016/j.jchf.2015.06.006) (PMID:26449997)
Krum, H. et al. (2015) The Aliskiren trial to minimize outcomes in patients with heart failure trial (ATMOSPHERE): revised statistical analysis plan and baseline characteristics. European Journal of Heart Failure, 17(10), pp. 1075-1083. (doi: 10.1002/ejhf.408) (PMID:26511146)
Jhund, P. et al. (2015) Mortality following a cardiovascular or renal event in patients with type 2 diabetes in the ALTITUDE trial. European Heart Journal, 36(36), pp. 2463-2469. (doi: 10.1093/eurheartj/ehv295) (PMID:26188211)
Girerd, N., Collier, T., Pocock, S., Krum, H., McMurray, J. J. , Swedberg, K., Van Veldhuisen, D. J., Vincent, J., Pitt, B. and Zannad, F. (2015) Clinical benefits of eplerenone in patients with systolic heart failure and mild symptoms when initiated shortly after hospital discharge: analysis from the EMPHASIS-HF trial. European Heart Journal, 36(34), pp. 2310-2317. (doi: 10.1093/eurheartj/ehv273) (PMID:26093641)
Charytan, D. M. et al. (2015) Cause of death in patients with diabetic CKD enrolled in the trial to reduce cardiovascular events with aranesp therapy (TREAT). American Journal of Kidney Diseases, 66(3), pp. 429-440. (doi: 10.1053/j.ajkd.2015.02.324) (PMID:25935581)
Fisher, M., Petrie, M. , Ambery, P., Donaldson, J., McMurray, J. J.V. and Ye, J. (2015) Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis. Lancet Diabetes and Endocrinology, 3(9), pp. 697-703. (doi: 10.1016/s2213-8587(15)00233-8) (PMID:26276240)
Kao, D. P., Lewsey, J. D. , Anand, I. S., Massie, B. M., Zile, M. R., Carson, P. E., McKelvie, R. S., Komajda, M., McMurray, J. J.V. and Lindenfeld, J. (2015) Characterization of subgroups of heart failure patients with preserved ejection fraction with possible implications for prognosis and treatment response. European Journal of Heart Failure, 17(9), pp. 925-935. (doi: 10.1002/ejhf.327) (PMID:26250359)
Platz, E., Jhund, P. S. , Campbell, R. T. and McMurray, J. (2015) Assessment and prevalence of pulmonary oedema in contemporary acute heart failure trials: a systematic review. European Journal of Heart Failure, 17(9), pp. 906-916. (doi: 10.1002/ejhf.321) (PMID:26230356) (PMCID:PMC4725064)
McMurray, J. J.V. (2015) It is BEAUTIFUL we should be concerned about, not SIGNIFY: is ivabradine less effective in ischaemic compared with non-ischaemic LVSD? European Heart Journal, 36(31), pp. 2047-2049. (doi: 10.1093/eurheartj/ehv190) (PMID:25994745)
Desai, A. S. et al. (2015) Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients. European Heart Journal, 36(30), pp. 1990-1997. (doi: 10.1093/eurheartj/ehv186) (PMID:26022006)
Mebazaa, A. et al. (2015) Recommendations on pre-hospital and early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine – short version. European Heart Journal, 36(30), pp. 1958-1966. (doi: 10.1093/eurheartj/ehv066) (PMID:25998514)
Askevold, E. T., Gullestad, L., Nymo, S., Kjekshus, J., Yndestad, A., Latini, R., Cleland, J. G.F. , McMurray, J. J.V. , Aukrust, P. and Ueland, T. (2015) Secreted frizzled related protein 3 in chronic heart failure: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA). PLoS ONE, 10(8), e0133970. (doi: 10.1371/journal.pone.0133970) (PMID:26288364) (PMCID:PMC4545831)
Jackson, C. E. et al. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3(8), pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014) (PMID:26251088)
Jhund, P. S. , Anand, I. S., Komajda, M., Claggett, B. L., McKelvie, R. S., Zile, M. R., Carson, P. E. and McMurray, J. J.V. (2015) Changes in N-terminal pro-B-type natriuretic peptide levels and outcomes in heart failure with preserved ejection fraction: an analysis of the I-Preserve study. European Journal of Heart Failure, 17(8), pp. 809-817. (doi: 10.1002/ejhf.274) (PMID:25921853)
Khazanie, P. et al. (2015) Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated heart failure outcome models. American Heart Journal, 170(2), pp. 290-297. (doi: 10.1016/j.ahj.2015.04.006) (PMID:26299226)
Lewis, E. F. et al. (2015) Race and ethnicity influences on cardiovascular and renal events in patients with diabetes mellitus. American Heart Journal, 170(2), 322-329.e4. (doi: 10.1016/j.ahj.2015.05.008) (PMID:26299230)
Preiss, D. et al. (2015) Prospective relationships between body weight and physical activity: an observational analysis from the NAVIGATOR study. BMJ Open, 5(8), e007901. (doi: 10.1136/bmjopen-2015-007901) (PMID:26275900) (PMCID:PMC4550730)
Rush, C. J., Campbell, R. T., Jhund, P. S. , Connolly, E. C., Preiss, D. , Gardner, R. S., Petrie, M. C. and McMurray, J. J.V. (2015) Falling cardiovascular mortality in heart failure with reduced ejection fraction and implications for clinical trials. JACC: Heart Failure, 3(8), pp. 603-614. (doi: 10.1016/j.jchf.2015.03.013) (PMID:26251086)
Yates, T. et al. (2015) Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial. Diabetic Medicine, 32(8), pp. 1090-1096. (doi: 10.1111/dme.12762) (PMID:25818859)
Emdin, C. A., Callender, T., Cao, J., McMurray, J. J.V. and Rahimi, K. (2015) Meta-analysis of large-scale randomized trials to determine the effectiveness of inhibition of the renin-angiotensin aldosterone system in heart failure. American Journal of Cardiology, 116(1), pp. 155-61. (doi: 10.1016/j.amjcard.2015.03.052) (PMID:25937349)
Cannon, J.A. et al. (2015) Clinical outcomes according to QRS duration and morphology in the eplerenone in mild patients: hospitalization and survIval study in heart failure (EMPHASIS-HF). European Journal of Heart Failure, 17(7), pp. 707-716. (doi: 10.1002/ejhf.303) (PMID:26139584)
Green, J. B. et al. (2015) Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. New England Journal of Medicine, 373(3), pp. 232-242. (doi: 10.1056/NEJMoa1501352) (PMID:26052984)
Harinstein, M. E. et al. (2015) Site selection for heart failure clinical trials in the USA. Heart Failure Reviews, 20(4), pp. 375-383. (doi: 10.1007/s10741-015-9473-z) (PMID:25649127)
Dalzell, J. R., Rocchiccioli, J. P., Weir, R. A.P., Jackson, C. E., Padmanabhan, N., Gardner, R. S., Petrie, M. C. and McMurray, J. J.V. (2015) The emerging potential of the apelin-APJ system in heart failure. Journal of Cardiac Failure, 21(6), pp. 489-498. (doi: 10.1016/j.cardfail.2015.03.007) (PMID:25795508)
Kristensen, S. L., Jhund, P. S. , Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Cleland, J. G.F. , Carson, P. E. and McMurray, J. J.V. (2015) Relative importance of history of heart failure hospitalization and N-terminal pro–B-type natriuretic peptide level as predictors of outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 3(6), pp. 478-486. (doi: 10.1016/j.jchf.2015.01.014) (PMID:26046842)
Mebazaa, A. et al. (2015) Recommendations on pre-hospital & early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergenc. European Journal of Heart Failure, 17(6), pp. 544-558. (doi: 10.1002/ejhf.289) (PMID:25999021)
Preiss, D. et al. (2015) The effect of statin therapy on heart failure events: a collaborative meta-analysis of unpublished data from major randomized trials. European Heart Journal, 36(24), pp. 1536-1546. (doi: 10.1093/eurheartj/ehv072) (PMID:25802390) (PMCID:PMC4769322)
Bentley-Lewis, R. et al. (2015) Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo. American Heart Journal, 169(5), 631-638.e7. (doi: 10.1016/j.ahj.2015.02.002) (PMID:25965710)
Abdul-Rahim, A. H. et al. (2015) Risk of stroke in chronic heart failure patients without atrial fibrillation: analysis of the controlled rosuvastatin in multinational trial heart failure (corona) and the gruppo italiano per lo studio della sopravvivenza nell'insufficienza cardiaca-heart failure (gissi-hf) trials. Circulation, 131(17), pp. 1486-1494. (doi: 10.1161/CIRCULATIONAHA.114.013760) (PMID:25810334)
Ezekowitz, J. A. et al. (2015) Clinical outcomes of patients with diabetes and atrial fibrillation treated with apixaban: results from the ARISTOTLE trial. European Heart Journal: Cardiovascular Pharmacotherapy, 1(2), pp. 86-94. (doi: 10.1093/ehjcvp/pvu024) (PMID:27533976)
Feinstein, M. J., Jhund, P. , Kang, J., Ning, H., Maggioni, A., Wikstrand, J., Kjekshus, J., Tavazzi, L., McMurray, J. and Lloyd-Jones, D. M. (2015) Do statins reduce the risk of myocardial infarction in patients with heart failure? A pooled individual-level reanalysis of CORONA and GISSI-HF. European Journal of Heart Failure, 17(4), pp. 434-441. (doi: 10.1002/ejhf.247) (PMID:25684642)
Vazir, A. et al. (2015) Prognostic importance of temporal changes in resting heart rate in heart failure patients: an analysis of the CHARM program. European Heart Journal, 36(11), pp. 669-675. (doi: 10.1093/eurheartj/ehu401) (PMID:25368202)
Campbell, R. T. et al. (2015) Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2(1), pp. 25-36. (doi: 10.1002/ehf2.12027) (PMID:27347426) (PMCID:PMC4864752)
DeVore, A. D. et al. (2015) Loop diuretic dose adjustments after a hospitalization for heart failure: insights from ASCEND-HF. European Journal of Heart Failure, 17(3), pp. 340-346. (doi: 10.1002/ejhf.235) (PMID:25619549)
Haver, V. G. et al. (2015) Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA). European Journal of Heart Failure, 17(3), pp. 313-9. (doi: 10.1002/ejhf.237) (PMID:25639660)
Katz, M., Califf, R. M., Sun, J.-L., McMurray, J. J.V. , Thomas, L. and Lopes, R. D. (2015) Venous thromboembolism and cardiovascular risk: results from the NAVIGATOR trial. American Journal of Medicine, 128(3), pp. 297-302. (doi: 10.1016/j.amjmed.2014.08.022) (PMID:25447626)
Metra, M. et al. (2015) Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study. Journal of Cardiac Failure, 21(3), pp. 179-88. (doi: 10.1016/j.cardfail.2014.12.012) (PMID:25573829)
Badar, A. A. et al. (2015) Clinical characteristics and outcomes of patients with angina and heart failure in the CHARM (Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity) programme. European Journal of Heart Failure, 17(2), pp. 196-204. (doi: 10.1002/ejhf.221)
Hijazi, Z. et al. (2015) Comparison of cardiac troponins i and t measured with high-sensitivity methods for evaluation of prognosis in atrial fibrillation: an ARISTOTLE substudy. Clinical Chemistry, 61(2), pp. 368-378. (doi: 10.1373/clinchem.2014.226936) (PMID:25451868)
Kristensen, S. L. et al. (2015) Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction. European Journal of Heart Failure, 17(2), pp. 169-176. (doi: 10.1002/ejhf.211) (PMID:25756844)
Ueland, T., Aukrust, P., Nymo, S. H., Kjekshus, J., McMurray, J. J.V. , Wikstrand, J., Block, D., Zaugg, C. and Gullestad, L. (2015) Novel extracellular matrix biomarkers as predictors of adverse outcome in chronic heart failure: association between biglycan and response to statin therapy in the CORONA trial. Journal of Cardiac Failure, 21(2), pp. 153-9. (doi: 10.1016/j.cardfail.2014.10.016) (PMID:25451704)
Abdul-Rahim, A.H. , Fulton, R.L., Frank, B., McMurray, J.J.V. and Lees, K.R. (2015) Associations of chronic heart failure with outcome in acute ischaemic stroke patients who received systemic thrombolysis: analysis from VISTA. European Journal of Neurology, 22(1), pp. 163-169. (doi: 10.1111/ene.12548) (PMID:25370204)
Kristensen, S. L. L. et al. (2015) International geographic variation in event rates in trials of heart failure with preserved and reduced ejection fraction. Circulation, 131(1), pp. 43-53. (doi: 10.1161/CIRCULATIONAHA.114.012284)
Packer, M. et al. (2015) Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation, 131(1), pp. 54-61. (doi: 10.1161/circulationaha.114.013748) (PMID:25403646) (PMCID:25403646)
Swerdlow, D. I. et al. (2015) HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet, 385(9965), pp. 351-361. (doi: 10.1016/S0140-6736(14)61183-1) (PMID:25262344) (PMCID:PMC4322187)
Tang, W.H. W. et al. (2015) Comparative assessment of short-term adverse events in acute heart failure with cystatin C and other estimates of renal function: results from the ASCEND-HF trial. JACC: Heart Failure, 3(1), pp. 40-9. (doi: 10.1016/j.jchf.2014.06.014) (PMID:25453534)
Ueland, T., Aukrust, P., Nymo, S. H., Kjekshus, J., McMurray, J. J.V. , Wikstrand, J., Wienhues-Thelen, U.-H., Block, D., Zaugg, C. and Gullestad, L. (2015) Predictive value of endostatin in chronic heart failure patients with poor kidney function. Cardiology, 130(1), pp. 17-22. (doi: 10.1159/000368220) (PMID:25428583)
Abdul-Rahim, A. H. et al. (2015) Response to Letter Regarding Article, “Risk of Stroke in Chronic Heart Failure Patients Without Atrial Fibrillation: Analysis of the Controlled Rosuvastatin in Multinational Trial Heart Failure (CORONA) and the Gruppo Italiano per lo Studio della Sopravvivenza nell’Insufficienza Cardiaca-Heart Failure (GISSI-HF) Trials.”. Circulation, 132(22), e358. (doi: 10.1161/CIRCULATIONAHA.115.018395) (PMID:26621661)
Abualnaja, S., Podder, M., Hernandez, A. F., McMurray, J. J. V. , Starling, R. C., O'Connor, C. M., Califf, R. M., Armstrong, P. W. and Ezekowitz, J. A. (2015) Acute heart failure and atrial fibrillation: insights from the acute study of clinical effectiveness of nesiritide in decompensated heart failure (ASCEND‐HF) trial. Journal of the American Heart Association, 4(8), e002092. (doi: 10.1161/JAHA.115.002092) (PMID:26304935) (PMCID:PMC4599466)
Badar, A. A. et al. (2015) Clinical characteristics and outcomes of patients with coronary artery disease and angina. Circulation: Heart Failure, 8(4), pp. 717-724. (doi: 10.1161/CIRCHEARTFAILURE.114.002024) (PMID:26067854)
Cannon, J. A., McMurray, J. J.V. and Quinn, T. J. (2015) ‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure. Alzheimer's Research and Therapy, 7, 22. (doi: 10.1186/s13195-015-0106-5) (PMID:25722749) (PMCID:PMC4342092)
Carson, P. E. et al. (2015) The hospitalization burden and post-hospitalization mortality risk in heart failure with preserved ejection fraction: results from the I-PRESERVE Trial (Irbesartan in Heart Failure and Preserved Ejection Fraction). JACC: Heart Failure, 3(6), pp. 429-441. (doi: 10.1016/j.jchf.2014.12.017) (PMID:25982110)
Jackson, C. E. et al. (2015) Differing prognostic value of pulse pressure in patients with heart failure with reduced or preserved ejection fraction: results from the MAGGIC individual patient meta-analysis. European Heart Journal, 36(18), pp. 1106-14. (doi: 10.1093/eurheartj/ehu490) (PMID:25616644)
Lam, C. S. P. et al. (2015) Sex differences in clinical characteristics and outcomes after myocardial infarction: insights from the valsartan in acute myocardial infarction trial (VALIANT). European Journal of Heart Failure, 17(3), pp. 301-312. (doi: 10.1002/ejhf.238) (PMID:25655011)
Lewsey, J. et al. (2015) Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005. BMC Neurology, 15(3), (doi: 10.1186/s12883-014-0257-1) (PMID:25591718) (PMCID:PMC4320501)
McMurray, J. , Zhu, L., McKillop, I. and Chen, H. (2015) Modelling system level health information exchange: an ontological approach. Studies in Health Technology and Informatics, 208, pp. 269-274. (PMID:25676986)
McMurray, J. (2015) Ethnic-specific normative reference values for echocardiographic LA and LV size, LV mass, and systolic function: the EchoNoRMAL Study. JACC: Cardiovascular Imaging, 8(6), pp. 656-665. (doi: 10.1016/j.jcmg.2015.02.014) (PMID:25981507)
McMurray, J. J.V. (2015) Neprilysin inhibition to treat heart failure: a tale of science, serendipity, and second chances. European Journal of Heart Failure, 17(3), pp. 242-7. (doi: 10.1002/ejhf.250) (PMID:25756942)
Roberts, E., Ludman, A. J., Dworzynski, K., Al-Mohammad, A., Cowie, M. R., McMurray, J. J. V. and Mant, J. (2015) The diagnostic accuracy of the natriuretic peptides in heart failure: systematic review and diagnostic meta-analysis in the acute care setting. British Medical Journal, 350, h910. (doi: 10.1136/bmj.h910) (PMID:25740799) (PMCID:PMC4353288)
Voors, A. A. et al. (2015) Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction. European Journal of Heart Failure, 17(5), pp. 510-517. (doi: 10.1002/ejhf.232) (PMID:25657064)
2014
Badar, A. A. et al. (2014) Relationship between angina pectoris and outcomes in patients with heart failure and reduced ejection fraction: an analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). European Heart Journal, 35(48), pp. 3426-3433. (doi: 10.1093/eurheartj/ehu342)
Damman, K., Tang, W. H. W., Testani, J. M. and McMurray, J. J. V. (2014) Terminology and definition of changes renal function in heart failure. European Heart Journal, 35(48), pp. 3413-3416. (doi: 10.1093/eurheartj/ehu320) (PMID:25157110)
Das, D., Bakal, J. A., Westerhout, C. M., Hernandez, A. F., O'Connor, C. M., Atar, D., McMurray, J. J.V. , Armstrong, P. W. and Ezekowitz, J. A. (2014) The association between meteorological events and acute heart failure: new insights from ASCEND-HF. International Journal of Cardiology, 177(3), pp. 819-824. (doi: 10.1016/j.ijcard.2014.11.066) (PMID:25465826)
van Diepen, S. et al. (2014) Acute decompensated heart failure patients admitted to critical care units: insights from ASCEND-HF. International Journal of Cardiology, 177(3), pp. 840-846. (doi: 10.1016/j.ijcard.2014.11.007) (PMID:25465830)
McMurray, J. J.V. , Packer, M. and Solomon, S. D. (2014) Neprilysin inhibition for heart failure. New England Journal of Medicine, 371(24), pp. 2336-2337. (doi: 10.1056/NEJMc1412654) (PMID:25494275)
Campbell, R. T., McKean, A. R. and McMurray, J. J.V. (2014) Acute heart failure: have we got it all wrong? European Journal of Heart Failure, 16(12), pp. 1263-1267. (doi: 10.1002/ejhf.197)
Chin, M. P. et al. (2014) Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl. Journal of Cardiac Failure, 20(12), pp. 953-958. (doi: 10.1016/j.cardfail.2014.10.001) (PMID:25307295)
Cotter, G. et al. (2014) Worsening heart failure, a critical event during hospital admission for acute heart failure: results from the VERITAS study. European Journal of Heart Failure, 16(12), pp. 1362-1371. (doi: 10.1002/ejhf.186) (PMID:25371147)
McMurray, J. J.V. and van Veldhuisen, D. J. (2014) β blockers, atrial fibrillation, and heart failure. Lancet, 384(9961), pp. 2181-2183. (doi: 10.1016/S0140-6736(14)62340-0) (PMID:25625384)
Preiss, D. et al. (2014) Change in levels of physical activity after diagnosis of type 2 diabetes: an observational analysis from the NAVIGATOR study. Diabetes, Obesity and Metabolism, 16(12), pp. 1265-1268. (doi: 10.1111/dom.12320) (PMID:24861892)
Cannon, J. A. and McMurray, J. J.V. (2014) Gut feelings about heart failure. Journal of the American College of Cardiology, 64(18), pp. 1915-1916. (doi: 10.1016/j.jacc.2014.04.088)
Adabag, S., Rector, T. S., Anand, I. S., McMurray, J. J. , Zile, M., Komajda, M., McKelvie, R. S., Massie, B. and Carson, P. E. (2014) A prediction model for sudden cardiac death in patients with heart failure and preserved ejection fraction. European Journal of Heart Failure, 16(11), pp. 1175-1182. (doi: 10.1002/ejhf.172)
Desai, A. S. et al. (2014) Influence of hospitalization for cardiovascular versus noncardiovascular reasons on subsequent mortality in patients with chronic heart failure across the spectrum of ejection fraction. Circulation: Heart Failure, 7(6), pp. 895-902. (doi: 10.1161/CIRCHEARTFAILURE.114.001567)
Lee, D., Wilson, K., Akehurst, R., Cowie, M.R., Zannad, F., Krum, H., van Veldhuisen, D.J., Vincent, J., Pitt, B. and McMurray, J.J.V. (2014) Cost-effectiveness of eplerenone in patients with systolic heart failure and mild symptoms. Heart, 100(21), pp. 1681-1687. (doi: 10.1136/heartjnl-2014-305673) (PMID:24993605) (PMCID:PMC4215293)
Oluleye, O. W., Rector, T. S., Win, S., McMurray, J. J. V. , Zile, M. R., Komajda, M., McKelvie, R. S., Massie, B., Carson, P. E. and Anand, I. S. (2014) History of atrial fibrillation as a risk factor in patients with heart failure and preserved ejection fraction. Circulation: Heart Failure, 7(6), pp. 960-966. (doi: 10.1161/CIRCHEARTFAILURE.114.001523)
Patel, P. A. et al. (2014) Hypotension during hospitalization for acute heart failure is independently associated with 30-day mortality: findings from ASCEND-HF. Circulation: Heart Failure, 7(6), pp. 918-925. (doi: 10.1161/CIRCHEARTFAILURE.113.000872)
Preiss, D. , McMurray, J. J. and Sattar, N. (2014) Treatment of severe hypertriglyceridaemia. Lancet Diabetes and Endocrinology, 2(11), p. 860. (doi: 10.1016/s2213-8587(14)70052-x) (PMID:25439459)
de Barros e Silva, P. G.M., Califf, R. M., Sun, J.-L., McMurray, J. J.V. , Holman, R., Haffner, S., Thomas, L. and Lopes, R. D. (2014) Chronic obstructive pulmonary disease and cardiovascular risk: Insights from the NAVIGATOR trial. International Journal of Cardiology, 176(3), pp. 1126-1128. (doi: 10.1016/j.ijcard.2014.07.297) (PMID:25220176)
Wong, C.M. et al. (2014) Heart failure in younger patients: the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC). European Heart Journal, 35(39), pp. 2714-2721. (doi: 10.1093/eurheartj/ehu216)
Dworzynski, K., Roberts, E., Ludman, A., Mant, J. and McMurray, J. (2014) Diagnosing and managing acute heart failure in adults: summary of NICE guidance. British Medical Journal, 349, g5695-g5695. (doi: 10.1136/bmj.g5695) (PMID:25296764)
Shah, A. M. et al. (2014) Reply: does speckle tracking really improve diagnosis and risk stratification in patients with HF with normal EF? Journal of the American College of Cardiology, 64(14), pp. 1535-1536. (doi: 10.1016/j.jacc.2014.04.084) (PMID:25277624)
McMurray, J. J.V. , Gerstein, H. C., Holman, R. R. and Pfeffer, M. A. (2014) Heart failure: a cardiovascular outcome in diabetes that can no longer be ignored. Lancet Diabetes and Endocrinology, 2(10), pp. 843-851. (doi: 10.1016/S2213-8587(14)70031-2)
Rahimi, K., Bennett, D., Conrad, N., Williams, T. M., Basu, J., Dwight, J., Woodward, M., Patel, A., McMurray, J. and MacMahon, S. (2014) Risk prediction in patients with heart failure. JACC: Heart Failure, 2(5), pp. 440-446. (doi: 10.1016/j.jchf.2014.04.008) (PMID:25194291)
Santos, A. B.S. et al. (2014) Impaired left atrial function in heart failure with preserved ejection fraction. European Journal of Heart Failure, 16(10), pp. 1096-1103. (doi: 10.1002/ejhf.147) (PMID:25138249)
Damman, K., Perez, A. C., Anand, I. S., Komajda, M., McKelvie, R. S., Zile, M. R., Massie, B., Carson, P. E. and McMurray, J. J.V. (2014) Worsening renal function and outcome in heart failure patients with preserved ejection fraction and the impact of angiotensin receptor blocker treatment. Journal of the American College of Cardiology, 64(11), pp. 1106-1113. (doi: 10.1016/j.jacc.2014.01.087)
Jessup, M., Fox, K. A.A., Komajda, M., McMurray, J. J.V. and Packer, M. (2014) PARADIGM-HF — The experts' discussion. New England Journal of Medicine, 371(11), e15. (doi: 10.1056/NEJMp1410203) (PMID:25184757)
McMurray, J. J.V. et al. (2014) Angiotensin–neprilysin inhibition versus enalapril in heart failure. New England Journal of Medicine, 371(11), pp. 993-1004. (doi: 10.1056/NEJMoa1409077) (PMID:25176015)
van Deursen, V.M. et al. (2014) Nesiritide, renal function, and associated outcomes during hospitalization for acute decompensated heart failure: results from the acute study of clinical effectiveness of nesiritide and decompensated heart failure (ASCEND-HF). Circulation, 130(12), pp. 958-965. (doi: 10.1161/CIRCULATIONAHA.113.003046) (PMID:25074507)
Callender, T. et al. (2014) Heart failure care in low- and middle-income countries: a systematic review and meta-analysis. PLoS Medicine, 11(8), e1001699. (doi: 10.1371/journal.pmed.1001699) (PMID:25117081) (PMCID:PMC4130667)
Jennings, C. G. et al. (2014) Up-titration of allopurinol in patients with gout. Seminars in Arthritis and Rheumatism, 44(1), pp. 25-30. (doi: 10.1016/j.semarthrit.2014.01.004)
Padwal, R. et al. (2014) The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: a meta-analysis of individual patient data. International Journal of Obesity, 38(8), pp. 1110-1114. (doi: 10.1038/ijo.2013.203) (PMID:24173404)
Bello, N. A., Claggett, B., Desai, A. S., McMurray, J. J. V. , Granger, C. B., Yusuf, S., Swedberg, K., Pfeffer, M. A. and Solomon, S. D. (2014) Influence of previous heart failure hospitalization on cardiovascular events in patients with reduced and preserved ejection fraction. Circulation: Heart Failure, 7(4), pp. 590-595. (doi: 10.1161/CIRCHEARTFAILURE.113.001281)
Böhm, M. et al. (2014) Relationship between heart rate and mortality and morbidity in the irbesartan patients with heart failure and preserved systolic function trial (I-Preserve). European Journal of Heart Failure, 16(7), pp. 778-787. (doi: 10.1002/ejhf.85)
Campbell, R. T. and McMurray, J. J.V. (2014) Comorbidities and differential diagnosis in heart failure with preserved ejection fraction. Heart Failure Clinics, 10(3), pp. 481-501. (doi: 10.1016/j.hfc.2014.04.009)
Holman, R. R. et al. (2014) Rationale for and design of the Acarbose Cardiovascular Evaluation (ACE) trial. American Heart Journal, 168(1), 23-29.e2. (doi: 10.1016/j.ahj.2014.03.021)
McMurray, J. J.V. et al. (2014) Baseline characteristics and treatment of patients in prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF). European Journal of Heart Failure, 16(7), pp. 817-825. (doi: 10.1002/ejhf.115) (PMID:24828035) (PMCID:PMC4312884)
Jhund, P. S. et al. (2014) Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: an analysis of the PARAMOUNT trial. European Journal of Heart Failure, 16(6), pp. 671-677. (doi: 10.1002/ejhf.76)
Rogers, J. K. et al. (2014) Effect of rosuvastatin on repeat heart failure hospitalizations: The CORONA Trial (Controlled Rosuvastatin Multinational Trial in Heart Failure). JACC: Heart Failure, 2(3), pp. 289-297. (doi: 10.1016/j.jchf.2013.12.007)
Gori, M. et al. (2014) Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction. European Journal of Heart Failure, 16(5), pp. 535-542. (doi: 10.1002/ejhf.67) (PMID:24574260)
Kalogeropoulos, A. P. et al. (2014) High-sensitivity C-reactive protein in acute heart failure: insights from the ASCEND-HF trial. Journal of Cardiac Failure, 20(5), pp. 319-326. (doi: 10.1016/j.cardfail.2014.02.002) (PMID:24530944)
Rogers, J. K., Pocock, S. J., McMurray, J. J.V. , Granger, C. B., Michelson, E. L., Östergren, J., Pfeffer, M. A., Solomon, S. D., Swedberg, K. and Yusuf, S. (2014) Corrigendum to ‘Analysing recurrent hospitalizations in heart failure: a review of statistical methodology, with application to CHARM-Preserved’ [Eur J Heart Fail2014;16:33-40]. European Journal of Heart Failure, 16(5), p. 592. (doi: 10.1002/ejhf.86)
Sliwa, K. et al. (2014) EURObservational research programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM. European Journal of Heart Failure, 16(5), pp. 583-591. (doi: 10.1002/ejhf.68)
Bello, N. A. et al. (2014) Retinopathy and clinical outcomes in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia. BMJ Open Diabetes Research and Care, 2(1), e000011. (doi: 10.1136/bmjdrc-2013-000011) (PMID:25452859) (PMCID:PMC4212578)
Butler, J. et al. (2014) Developing therapies for heart failure with preserved ejection fraction. JACC: Heart Failure, 2(2), pp. 97-112. (doi: 10.1016/j.jchf.2013.10.006) (PMID:24720916) (PMCID:PMC4028447)
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