Mrs Katrina Stevenson
- Technician (Clinical Research Garscube)
telephone:
01413304417
email:
Katrina.Stevenson@glasgow.ac.uk
pronouns:
She/her/hers
112, Level 1, Wolfson Wohl, Garscube
Publications
2024
Tesson, M., Stevenson, K., Karim, S. A., Nixon, C., Chalmers, A. J. , Sansom, O. J., O'Neill, E., Jones, K. and Morton, J. P. (2024) Targeted irradiation in an autochthonous mouse model of pancreatic cancer. Disease Models and Mechanisms, 17(3), dmm050463. (doi: 10.1242/dmm.050463) (PMID:38421046) (PMCID:PMC10958199)
Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)
2023
Koessinger, D. et al. (2023) Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness. Neuro-Oncology Advances, 5(1), vdad067. (doi: 10.1093/noajnl/vdad067) (PMID:37334166) (PMCID:PMC10276538)
2022
Falcone, M. et al. (2022) Sensitisation of cancer cells to radiotherapy by serine and glycine starvation. British Journal of Cancer, 127(10), pp. 1773-1786. (doi: 10.1038/s41416-022-01965-6) (PMID:36115879) (PMCID:PMC9643498)
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Jackson, M. R. et al. (2022) Low-dose lung radiotherapy for COVID-19 lung disease: a preclinical efficacy study in a bleomycin model of pneumonitis. International Journal of Radiation Oncology, Biology, Physics, 112(1), pp. 197-211. (doi: 10.1016/j.ijrobp.2021.08.029) (PMID:34478832) (PMCID:PMC8406661)
2021
Birch, J. et al. (2021) Inhibition of ATR prevents macropinocytosis driven retraction of neurites and opposes invasion in GBM. Research Square, (doi: 10.21203/rs.3.rs-967109/v1) (PMID:37936324)
2020
Koessinger, A. L., Koessinger, D., Stevenson, K., Cloix, C., Mitchell, L., Nixon, C., Gomez-Roman, N. , Chalmers, A. J. , Norman, J. C. and Tait, S. W.G. (2020) Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts. Scientific Reports, 10, 15361. (doi: 10.1038/s41598-020-72322-x) (PMID:32958777) (PMCID:PMC7506024)
Gomez-Roman, N. , Chong, M. Y., Chahal, S. K., Caragher, S. P., Jackson, M. R. , Stevenson, K. H., Dongre, S. A. and Chalmers, A. J. (2020) Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ. Molecular Cancer Therapeutics, 19(2), pp. 575-589. (doi: 10.1158/1535-7163.MCT-18-1320) (PMID:31672763)
2019
Bilsland, A. E. , Liu, Y., Turnbull, A., Sumpton, D., Stevenson, K., Cairney, C. J., Boyd, S. M., Roffey, J., Jenkinson, D. and Keith, W. N. (2019) A novel pyrazolopyrimidine ligand of human PGK1 and stress sensor DJ1 modulates the shelterin complex and telomere length regulation. Neoplasia, 21(9), pp. 893-907. (doi: 10.1016/j.neo.2019.07.008) (PMID:31401411) (PMCID:PMC6700475)
Rutherford, A., Stevenson, K., Tulk, A. and Chalmers, A. J. (2019) Evaluation of four different small animal radiation plans on tumour and normal tissue dosimetry in a glioblastoma mouse model. British Journal of Radiology, 92(1095), 20180469. (doi: 10.1259/bjr.20180469) (PMID:30362815) (PMCID:PMC6541187)
2018
Carruthers, R. D. et al. (2018) Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells. Cancer Research, 78(17), pp. 5060-5071. (doi: 10.1158/0008-5472.CAN-18-0569) (PMID:29976574) (PMCID:PMC6128404)
2017
Cairney, C. J. et al. (2017) A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. PLoS Genetics, 13(8), e1006942. (doi: 10.1371/journal.pgen.1006942) (PMID:28806777) (PMCID:PMC5570495)
Gomez-Roman, N. , Stevenson, K., Gilmour, L., Hamilton, G. and Chalmers, A. (2017) A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses. Neuro-Oncology, 19(2), pp. 229-241. (doi: 10.1093/neuonc/now164) (PMID:27576873) (PMCID:PMC5463789)
2014
Bilsland, A. E. , Stevenson, K., Liu, Y., Hoare, S., Cairney, C. J., Roffey, J. and Keith, W. N. (2014) Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms. PLoS Computational Biology, 10(2), e1003448. (doi: 10.1371/journal.pcbi.1003448) (PMID:24550717) (PMCID:PMC3923661)
2009
Bilsland, A.E., Hoare, S.F., Stevenson, K.H., Plumb, J.A., Gomez-Roman, N. , Cairney, C.J., Burns, S., Lafferty-Whyte, K., Hammonds, T. and Keith, W.N. (2009) Dynamic telomerase gene suppression via network effects of GSK3 inhibition. PLoS ONE, 4(7), e6459. (doi: 10.1371/journal.pone.0006459)
McGlynn, L.M., Stevenson, K., Lamb, K., Zino, S., Brown, M., Prina, A., Kingsmore, D. and Shiels, P.G. (2009) Cellular senescence in pre-transplant renal biopsies predicts postoperative organ function. Aging Cell, 8(1), pp. 45-51. (doi: 10.1111/j.1474-9726.2008.00447.x)
Articles
Tesson, M., Stevenson, K., Karim, S. A., Nixon, C., Chalmers, A. J. , Sansom, O. J., O'Neill, E., Jones, K. and Morton, J. P. (2024) Targeted irradiation in an autochthonous mouse model of pancreatic cancer. Disease Models and Mechanisms, 17(3), dmm050463. (doi: 10.1242/dmm.050463) (PMID:38421046) (PMCID:PMC10958199)
Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)
Koessinger, D. et al. (2023) Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness. Neuro-Oncology Advances, 5(1), vdad067. (doi: 10.1093/noajnl/vdad067) (PMID:37334166) (PMCID:PMC10276538)
Falcone, M. et al. (2022) Sensitisation of cancer cells to radiotherapy by serine and glycine starvation. British Journal of Cancer, 127(10), pp. 1773-1786. (doi: 10.1038/s41416-022-01965-6) (PMID:36115879) (PMCID:PMC9643498)
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Jackson, M. R. et al. (2022) Low-dose lung radiotherapy for COVID-19 lung disease: a preclinical efficacy study in a bleomycin model of pneumonitis. International Journal of Radiation Oncology, Biology, Physics, 112(1), pp. 197-211. (doi: 10.1016/j.ijrobp.2021.08.029) (PMID:34478832) (PMCID:PMC8406661)
Birch, J. et al. (2021) Inhibition of ATR prevents macropinocytosis driven retraction of neurites and opposes invasion in GBM. Research Square, (doi: 10.21203/rs.3.rs-967109/v1) (PMID:37936324)
Koessinger, A. L., Koessinger, D., Stevenson, K., Cloix, C., Mitchell, L., Nixon, C., Gomez-Roman, N. , Chalmers, A. J. , Norman, J. C. and Tait, S. W.G. (2020) Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts. Scientific Reports, 10, 15361. (doi: 10.1038/s41598-020-72322-x) (PMID:32958777) (PMCID:PMC7506024)
Gomez-Roman, N. , Chong, M. Y., Chahal, S. K., Caragher, S. P., Jackson, M. R. , Stevenson, K. H., Dongre, S. A. and Chalmers, A. J. (2020) Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ. Molecular Cancer Therapeutics, 19(2), pp. 575-589. (doi: 10.1158/1535-7163.MCT-18-1320) (PMID:31672763)
Bilsland, A. E. , Liu, Y., Turnbull, A., Sumpton, D., Stevenson, K., Cairney, C. J., Boyd, S. M., Roffey, J., Jenkinson, D. and Keith, W. N. (2019) A novel pyrazolopyrimidine ligand of human PGK1 and stress sensor DJ1 modulates the shelterin complex and telomere length regulation. Neoplasia, 21(9), pp. 893-907. (doi: 10.1016/j.neo.2019.07.008) (PMID:31401411) (PMCID:PMC6700475)
Rutherford, A., Stevenson, K., Tulk, A. and Chalmers, A. J. (2019) Evaluation of four different small animal radiation plans on tumour and normal tissue dosimetry in a glioblastoma mouse model. British Journal of Radiology, 92(1095), 20180469. (doi: 10.1259/bjr.20180469) (PMID:30362815) (PMCID:PMC6541187)
Carruthers, R. D. et al. (2018) Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells. Cancer Research, 78(17), pp. 5060-5071. (doi: 10.1158/0008-5472.CAN-18-0569) (PMID:29976574) (PMCID:PMC6128404)
Cairney, C. J. et al. (2017) A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. PLoS Genetics, 13(8), e1006942. (doi: 10.1371/journal.pgen.1006942) (PMID:28806777) (PMCID:PMC5570495)
Gomez-Roman, N. , Stevenson, K., Gilmour, L., Hamilton, G. and Chalmers, A. (2017) A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses. Neuro-Oncology, 19(2), pp. 229-241. (doi: 10.1093/neuonc/now164) (PMID:27576873) (PMCID:PMC5463789)
Bilsland, A. E. , Stevenson, K., Liu, Y., Hoare, S., Cairney, C. J., Roffey, J. and Keith, W. N. (2014) Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms. PLoS Computational Biology, 10(2), e1003448. (doi: 10.1371/journal.pcbi.1003448) (PMID:24550717) (PMCID:PMC3923661)
Bilsland, A.E., Hoare, S.F., Stevenson, K.H., Plumb, J.A., Gomez-Roman, N. , Cairney, C.J., Burns, S., Lafferty-Whyte, K., Hammonds, T. and Keith, W.N. (2009) Dynamic telomerase gene suppression via network effects of GSK3 inhibition. PLoS ONE, 4(7), e6459. (doi: 10.1371/journal.pone.0006459)
McGlynn, L.M., Stevenson, K., Lamb, K., Zino, S., Brown, M., Prina, A., Kingsmore, D. and Shiels, P.G. (2009) Cellular senescence in pre-transplant renal biopsies predicts postoperative organ function. Aging Cell, 8(1), pp. 45-51. (doi: 10.1111/j.1474-9726.2008.00447.x)
Research datasets
2018
Turnbull, A. P., Bilsland, A., Liu, Y., Sumpton, D., Stevenson, K., Cairney, C., Roffey, J., Jenkinson, D. and Keith, N. (2018) PGK1 in complex with CRT0063465 (3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid). [Data Collection]
2017
Cairney, C., Godwin, L., Bilsland, A., Burns, S., Stevenson, K., McGarry, L., Revie, J., Moore, J., Wiggans, C., Collinson, R., Mudd, C., Tsonou, E., Sadaie, M., Bennet, D., Narita, M., Torrance, C. and Keith, N. (2017) A ‘synthetic-sickness’ screen for senescence re-engagement targets in mutant cancer backgrounds. [Data Collection]