Dr David Lewis

Senior Lecturer (CRUK Scotland Institute)

telephone: 01413308161
email: David.Lewis@glasgow.ac.uk

Import to contacts

https://orcid.org/0000-0001-9329-1326

Research interests

Link to research pages

Research groups

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2012 | 2011 | 2010 | 2009

Number of items: 32.

2025

Müller, M. et al. (2025) Human-correlated genetic models identify precision therapy for liver cancer. Nature, (doi: 10.1038/s41586-025-08585-z) (PMID:39972137) (Early Online Publication)

2024

Malviya, G. et al. (2024) Noninvasive stratification of colon cancer by multiplex PET imaging. Clinical Cancer Research, 30(8), pp. 1518-1529. (doi: 10.1158/1078-0432.ccr-23-1063) (PMID:38493804) (PMCID:PMC11016897)

2023

Lewis, David Y. ORCID: https://orcid.org/0000-0001-9329-1326 (2023) Multiplexing autoradiography. In: Witney, Timothy H. and Shuhendler, Adam J. (eds.) Positron Emission Tomography: Methods and Protocols. Series: Methods in molecular biology (2729). Humana: New York NY, pp. 423-439. ISBN 9781071634998 (doi: 10.1007/978-1-0716-3499-8_24)

Dzien, P. et al. (2023) Positron emission tomography imaging of the sodium iodide symporter senses real-time energy stress in vivo. Cancer and Metabolism, 11, 14. (doi: 10.1186/s40170-023-00314-2) (PMID:37679822) (PMCID:PMC10486058)

Farahmand, P. et al. (2023) Asbestos accelerates disease onset in a genetic model of malignant pleural mesothelioma. Frontiers in Toxicology, 5, 1200650. (doi: 10.3389/ftox.2023.1200650) (PMID:37441092) (PMCID:PMC10333928)

Brown, Gavin, Soloviev, Dmitry and Lewis, David Y. ORCID: https://orcid.org/0000-0001-9329-1326 (2023) Radiosynthesis and analysis of (S)-4-(3-[18F]fluoropropyl)-L-glutamic acid. Molecular Imaging and Biology, 25(3), pp. 586-595. (doi: 10.1007/s11307-022-01793-3) (PMID:36525163) (PMCID:PMC10172245)

Villar, V. H. et al. (2023) Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer. Nature Chemical Biology, 19(3), pp. 292-300. (doi: 10.1038/s41589-022-01154-9) (PMID:36280791) (PMCID:PMC9974483)

2022

Soloviev, Dmitry, Dzien, Piotr, Mackintosh, Agata, Malviya, Gaurav ORCID: https://orcid.org/0000-0003-0736-7991, Brown, Gavin and Lewis, David ORCID: https://orcid.org/0000-0001-9329-1326 (2022) High molar activity [18F]tetrafluoroborate synthesis for sodium iodide symporter imaging by PET. EJNMMI Radiopharmacy and Chemistry, 7, 32. (doi: 10.1186/s41181-022-00185-w) (PMID:36512196) (PMCID:PMC9747990)

Müller, M. et al. (2022) Human-correlated genetic HCC models identify combination therapy for precision medicine [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1638504/v1)

2021

Najumudeen, A. K. et al. (2021) The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer. Nature Genetics, 53, pp. 16-26. (doi: 10.1038/s41588-020-00753-3) (PMID:33414552)

2020

Malviya, G. et al. (2020) 18F-Fluciclovine PET metabolic imaging reveals prostate cancer tumour heterogeneity associated with disease resistance to androgen deprivation therapy. EJNMMI Research, 10, 143. (doi: 10.1186/s13550-020-00728-9) (PMID:33237350) (PMCID:PMC7688773)

2019

McCormick, P. N. et al. (2019) Assessment of tumor redox status through (S)-4-(3-[18F]fluoropropyl)-L-glutamic acid positron emission tomography imaging of system xc- activity. Cancer Research, 79(4), pp. 853-863. (doi: 10.1158/0008-5472.CAN-18-2634) (PMID:30401715) (PMCID:PMC6379064)

Witney, Timothy H. and Lewis, David Y. ORCID: https://orcid.org/0000-0001-9329-1326 (2019) Imaging cancer metabolism with Positron Emission Tomography (PET). In: Haznadar, Majda (ed.) Cancer Metabolism: Methods and Protocols. Series: Methods in Molecular Biology, 1928. Springer, pp. 29-44. ISBN 9781493990269 (doi: 10.1007/978-1-4939-9027-6_2)

2018

Serrao, E.M., Kettunen, M.I., Rodrigues, T.B., Lewis, D.Y. ORCID: https://orcid.org/0000-0001-9329-1326, Gallagher, F.A., Hu, D.E. and Brindle, K.M. (2018) Analysis of 13 C and 14 C labeling in pyruvate and lactate in tumor and blood of lymphoma-bearing mice injected with 13 C- and 14 C-labeled pyruvate. NMR in Biomedicine, 31(5), e3901. (doi: 10.1002/nbm.3901) (PMID:29457661) (PMCID:PMC5947589)

2017

Heinzmann, K. et al. (2017) Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models. EJNMMI Research, 7(1), 99. (doi: 10.1186/s13550-017-0349-1) (PMID:29247446) (PMCID:PMC5732122)

Brindle, Kevin M., Izquierdo-García, José L., Lewis, David Y. ORCID: https://orcid.org/0000-0001-9329-1326, Mair, Richard J. and Wright, Alan J. (2017) Brain tumor imaging. Journal of Clinical Oncology, 35(21), pp. 2432-2438. (doi: 10.1200/JCO.2017.72.7636) (PMID:28640699)

Neves, A. A. et al. (2017) Rapid imaging of tumor cell death in vivo using the c2a domain of synaptotagmin-I. Journal of Nuclear Medicine, 58(6), pp. 881-887. (doi: 10.2967/jnumed.116.183004) (PMID:28209913)

2016

Heinzmann, K. et al. (2016) The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models. EJNMMI Research, 6(1), 63. (doi: 10.1186/s13550-016-0218-3) (PMID:27515446) (PMCID:PMC4980847)

Serrao, E. M. et al. (2016) MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model. Gut, 65(3), pp. 465-475. (doi: 10.1136/gutjnl-2015-310114) (PMID:26347531) (PMCID:PMC4789827)

2015

Irkle, A. et al. (2015) Identifying active vascular microcalcification by ¹⁸F-sodium fluoride positron emission tomography. Nature Communications, 6, 7495. (doi: 10.1038/ncomms8495) (PMID:26151378) (PMCID:PMC4506997)

Lewis, David Y. ORCID: https://orcid.org/0000-0001-9329-1326, Soloviev, Dmitry and Brindle, Kevin M. (2015) Imaging tumor metabolism using positron emission tomography. Cancer Journal, 21(2), pp. 129-136. (doi: 10.1097/PPO.0000000000000105) (PMID:25815854) (PMCID:PMC4413031)

2014

Lewis, D.Y. ORCID: https://orcid.org/0000-0001-9329-1326, Boren, J., Shaw, G.L., Bielik, R., Ramos-Montoya, A., Larkin, T.J., Martins, C.P., Neal, D.E., Soloviev, D. and Brindle, K.M. (2014) Late imaging with [1-¹¹C]acetate improves detection of tumor fatty acid synthesis with PET. Journal of Nuclear Medicine, 55(7), pp. 1144-1149. (doi: 10.2967/jnumed.113.134437) (PMID:24777291)

Patrick, P.S. et al. (2014) Dual-modality gene reporter for in vivo imaging. Proceedings of the National Academy of Sciences of the United States of America, 111(1), pp. 415-420. (doi: 10.1073/pnas.1319000111) (PMID:24347640) (PMCID:PMC3890795)

Lewis, David Y., Champion, Susan ORCID: https://orcid.org/0000-0001-5542-6349, Wyper, David, Dewar, Deborah ORCID: https://orcid.org/0000-0002-8388-2779 and Pimlott, Sally ORCID: https://orcid.org/0000-0002-8396-3392 (2014) Assessment of [125I]WYE-230949 as a novel histamine H3 receptor radiopharmaceutical. PLoS ONE, 9(12), e115876. (doi: 10.1371/journal.pone.0115876) (PMID:25542008) (PMCID:PMC4277420)

2012

Soloviev, Dmitry, Lewis, David ORCID: https://orcid.org/0000-0001-9329-1326, Honess, Davina and Aboagye, Eric (2012) [18F]FLT: An imaging biomarker of tumour proliferation for assessment of tumour response to treatment. European Journal of Cancer, 48(4), pp. 416-424. (doi: 10.1016/j.ejca.2011.11.035) (PMID:22209266)

2011

Gallagher, F.A., Bohndiek, S.E., Kettunen, M.I., Lewis, D.Y. ORCID: https://orcid.org/0000-0001-9329-1326, Soloviev, D. and Brindle, K.M. (2011) Hyperpolarized 13C MRI and PET: In vivo tumor biochemistry. Journal of Nuclear Medicine, 52(9), pp. 1333-1336. (doi: 10.2967/jnumed.110.085258) (PMID:21849405)

Neves, André A., Stöckmann, Henning, Harmston, Rebecca R., Pryor, Helen J., Alam, Israt S., Ireland-Zecchini, Heather, Lewis, David Y. ORCID: https://orcid.org/0000-0001-9329-1326, Lyons, Scott K., Leeper, Finian J. and Brindle, Kevin M. (2011) Imaging sialylated tumor cell glycans in vivo. FASEB Journal, 25(8), pp. 2528-2537. (doi: 10.1096/fj.10-178590) (PMID:21493886)

Crossan, G. P. et al. (2011) Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nature Genetics, 43(2), pp. 147-152. (doi: 10.1038/ng.752) (PMID:21240276) (PMCID:PMC3624090)

2010

Lewis, David Y. ORCID: https://orcid.org/0000-0001-9329-1326 and Brett, Ros R. (2010) Activity-based anorexia in C57/BL6 mice: Effects of the phytocannabinoid, △9-tetrahydrocannabinol (THC) and the anandamide analogue, OMDM-2. European Neuropsychopharmacology, 20(9), pp. 622-631. (doi: 10.1016/j.euroneuro.2010.04.002) (PMID:20471226)

Lewis, D.Y., Champion, S. ORCID: https://orcid.org/0000-0001-5542-6349, Dewar, D. ORCID: https://orcid.org/0000-0002-8388-2779, Honey, G., Gross, J., Robichaud, A.J., Welch, A., Wyper, D. and Pimlott, S. ORCID: https://orcid.org/0000-0002-8396-3392 (2010) Characterisation of novel histamine H3 receptor tracers for SPECT. Molecular Imaging and Biology, 12(S122), pp. 462-493.

2009

Champion, S. ORCID: https://orcid.org/0000-0001-5542-6349, Lewis, D., Dewar, D. ORCID: https://orcid.org/0000-0002-8388-2779, Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. ORCID: https://orcid.org/0000-0002-8396-3392 (2009) Radiosynthesis and evaluation of novel histamine H3 tracers. Eighteenth International Symposium on Radiopharmaceutical Sciences, Edmonton, Canada, 12 – 17 Jul 2009. S381. (doi: 10.1002/jlcr.1646)

Lewis, D., Champion, S. ORCID: https://orcid.org/0000-0001-5542-6349, Dewar, D. ORCID: https://orcid.org/0000-0002-8388-2779, Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. ORCID: https://orcid.org/0000-0002-8396-3392 (2009) Characterisation of Novel Histamine H3 receptor tracers for SPECT. Journal of Labelled Compounds and Radiopharmaceuticals, 52(S1), S381. (doi: 10.1002/jlcr.1646)

This list was generated on Sat Jun 14 17:45:47 2025 BST.

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