Translating Novel RT Strategies into Clinical Trials
The translating novel radiotherapy technologies into clinical trials theme was established to build a collaborative multidisciplinary research team focused on evaluation and clinical translation of emerging imaging and radiotherapy technologies.
Membership
The theme membership consists of a growing, multidisciplinary group of clinical practitioners, academic researchers and CRUK RadNet members with expertise including clinical oncology, medical physics, radiobiology, imaging, bioinformatics, and clinical trial development.
Theme Leads
- Professor Anthony Chalmers, Chair of Clinical Oncology (University of Glasgow)
- Professor Andrew Reilly, Honorary Professor (University of Glasgow)
- Dr Aileen Duffton, Honorary Senior Lecturer (University of Glasgow)
Members
Dr Derek Grose, Honorary Clinical Associate Professor (University of Glasgow)
Dr Ross Carruthers
Dr Stefan Nowicki
Lynsey Devlin, Honorary Lecturer (University of Glasgow)
Aoife Williamson, Honorary Lecturer (University of Glasgow)
Dr Laura Grocutt, Honorary Research Fellow (University of Glasgow)
Dr Stacey Holloway, Research Fellow (University of Glasgow)
Robyn Stansbridge
Research Projects
- Advanced imaging technologies - Using advanced, mutlimodal imaging to support and evaluate novel radiotherapy approaches e.g. CT, PET, MR for assessing treatment response, defining treatment volumes, and tracking changes during therapy. Examples of ongoing studies include AIR-PANC and AIR-REC which are using functional MRI to monitor longitudinal changes in tumours during a course of radiotherapy.
- Adaptive RT (ART) - Development and evaluation of new ART treatment strategies, including evaluation of the ETHOS ART platform. Studies are informed by emerging biological and technical insights, and designed with the feasibility of early clinical trials in mind.
As a new focus group, the project portfolio will expand through pump-priming, model development awards, collaborative initiatives, and national funding opportunities.
Funding
Current activity within the theme is supported through CRUK Glasgow RadNet+ Pump Priming, College of Radiographers Industry Partnership Scheme (CoRIPS), Beatson Cancer Charity.
The group also supports researchers in securing external funding, with anticipated outputs to include multiple successful project grant applications and fellowship awards from national funders.
Networks and Collaborations
The theme works closely with other CRUK Glasgow RadNet scientific themes, as well as national and international radiotherapy research networks e.g. UK SABR consortium, European Society of Radiation Oncology (ESTRO). These collaborations support shared infrastructure, expert study development, and will enable the translation of novel radiotherapy technologies into clinical evaluation.