Dr Cassandra Sampaio Baptista

  • Lecturer (Stroke & Brain Imaging)

Research interests

I am a neuroscientist using a multidisciplinary approach to investigate functional and structural plasticity, from the cellular level to systems levels, in healthy and clinical populations such as stroke survivors. I am a lecturer and principal investigator at the Institute of Neuroscience and Psychology and affiliated with GEMRIC (https://www.gemric.gla.ac.uk/), CCNi and the Centre for Neuroscience. I graduated with a Msc and Dphil (PhD) in Neuroscience from the University of Oxford under the supervision of Professor Heidi Johansen-Berg and Professor David Bannerman. My research focuses on brain plasticity in response to experiences such as skill learning or rehabilitation during adulthood, with the aim to harness brain plasticity to improve learning, rehabilitation and promote healthy aging. I use behavioural interventions and techniques that modulate brain activity to assess these effects on brain structure and function. For instance, I'm currently using neurofeedback fMRI to investigate how modulation of brain activity can lead to brain changes and behavioural improvements as a potential adjunct rehabilitation therapy for stroke survivors. Further, I'm using preclinical magnetic resonance imaging (MRI) as a translational tool in conjunction with established cellular techniques to elucidate the underlying cellular mechanisms of brain plasticity. I've made important contributions to the field of white matter and myelin plasticity, demonstrating that myelin plays an overlooked role in motor learning. I welcome interest and inquiries from prospective students and postdocs to join my group.


Publications

List by: Type | Date

Jump to: 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011
Number of items: 18.

2020

Barron, H. C. , Mars, R. B. , Dupret, D. , Lerch, J. and Sampaio-Baptista, C. (2020) Cross-species neuroscience: closing the explanatory gap. Philosophical Transactions of the Royal Society B: Biological Sciences, (Accepted for Publication)

Sampaio-Baptista, C. et al. (2020) White matter structure and myelin-related gene expression alterations with experience in adult rats. Progress in Neurobiology, 187, 101770. (doi: 10.1016/j.pneurobio.2020.101770) (PMID:32001310) (PMCID:PMC7086231)

2019

Sampaio-Baptista, C. , Diosi, K. and Johnansen-Berg, H. (2019) Magnetic resonance techniques for imaging white matter. In: Lyons, D. A. and Kegel, L. (eds.) Oligodendrocytes: Methods and Protocols. Series: Methods in molecular biology (1936). Humana Press: New York, NY, pp. 397-407. ISBN 9781493990702 (doi:10.1007/978-1-4939-9072-6_22)

2018

Lazari, A. , Koudelka, S. and Sampaio-Baptista, C. (2018) Experience-related reductions of myelin and axon diameter in adulthood. Journal of Neurophysiology, 120(4), pp. 1772-1775. (doi: 10.1152/jn.00070.2018) (PMID:30207857) (PMCID:PMC6230794)

Neyedli, H. F. , Sampaio-Baptista, C. , Kirkman, M. A. , Havard, D. , Lührs, M. , Ramsden, K. , Flitney, D. D. , Clare, S. , Goebel, R. and Johansen-Berg, H. (2018) Increasing lateralized motor activity in younger and older adults using Real-time fMRI during executed movements. Neuroscience, 378, pp. 165-174. (doi: 10.1016/j.neuroscience.2017.02.010) (PMID:28214578) (PMCID:PMC5953409)

Huang, H. et al. (2018) Development of white matter microstructure in relation to verbal and visuospatial working memory—a longitudinal study. PLoS ONE, 13(4), e0195540. (doi: 10.1371/journal.pone.0195540) (PMID:29689058) (PMCID:PMC5916522)

Heath, F. , Hurley, S. A. , Johansen-Berg, H. and Sampaio-Baptista, C. (2018) Advances in noninvasive myelin imaging. Developmental Neurobiology, 78(2), pp. 136-151. (doi: 10.1002/dneu.22552) (PMID:29082667) (PMCID:PMC5813152)

Sampaio-Baptista, C. , Sanders, Z.-B. and Johansen-Berg, H. (2018) Structural plasticity in adulthood with motor learning and stroke rehabilitation. Annual Review of Neuroscience, 41, pp. 25-40. (doi: 10.1146/annurev-neuro-080317-062015) (PMID:29490196)

2017

Sampaio-Baptista, C. and Johansen-Berg, H. (2017) White matter plasticity in the adult brain. Neuron, 96(6), pp. 1239-1251. (doi: 10.1016/j.neuron.2017.11.026) (PMID:29268094) (PMCID:PMC5766826)

Kaller, M. S. , Lazari, A. , Blanco-Duque, C. , Sampaio-Baptista, C. and Johansen-Berg, H. (2017) Myelin plasticity and behaviour — connecting the dots. Current Opinion in Neurobiology, 47, pp. 86-92. (doi: 10.1016/j.conb.2017.09.014) (PMID:29054040) (PMCID:PMC5844949)

2016

Krogsrud, S. K. et al. (2016) Changes in white matter microstructure in the developing brain—a longitudinal diffusion tensor imaging study of children from 4 to 11 years of age. NeuroImage, 124(Part A), pp. 473-486. (doi: 10.1016/j.neuroimage.2015.09.017) (PMID:26375208) (PMCID:PMC4655940)

2015

Sampaio-Baptista, C. , Filippini, N. , Stagg, C. J. , Near, J. , Scholz, J. and Johansen-Berg, H. (2015) Changes in functional connectivity and GABA levels with long-term motor learning. NeuroImage, 106, pp. 15-20. (doi: 10.1016/j.neuroimage.2014.11.032) (PMID:25463472) (PMCID:PMC4405007)

2014

Sampaio-Baptista, C. , Scholz, J. , Jenkinson, M. , Thomas, A. G. , Filippini, N. , Smit, G. , Douaud, G. and Johansen-Berg, H. (2014) Gray matter volume is associated with rate of subsequent skill learning after a long term training intervention. NeuroImage, 96, pp. 158-166. (doi: 10.1016/j.neuroimage.2014.03.056) (PMID:24680712) (PMCID:PMC4075341)

Stagg, C. J. , Bachtiar, V. , Amadi, U. , Gudberg, C. A. , Ilie, A. S. , Sampaio-Baptista, C. , O'Shea, J. , Woolrich, M. and Smith, S. M. (2014) Local GABA concentration is related to network-level resting functional connectivity. eLife, 3, e01465. (doi: 10.7554/eLife.01465.001) (PMID:24668166) (PMCID:PMC3964822)

Banerjee, A. , González-Rueda, A. , Sampaio-Baptista, C. , Paulsen, O. and Rodríguez-Moreno, A. (2014) Distinct mechanisms of spike timing-dependent LTD at vertical and horizontal inputs onto L2/3 pyramidal neurons in mouse barrel cortex. Physiological Reports, 2(3), e00271. (doi: 10.1002/phy2.271) (PMID:24760524) (PMCID:PMC4002250)

2013

Sampaio-Baptista, C. et al. (2013) Motor skill learning induces changes in white matter microstructure and myelination. Journal of Neuroscience, 33(50), pp. 19499-19503. (doi: 10.1523/JNEUROSCI.3048-13.2013) (PMID:24336716) (PMCID:PMC3858622)

2012

Johansen-Berg, H. , Sampaio Baptista, C. and Thomas, A. G. (2012) Human structural plasticity at record speed. Neuron, 73(6), pp. 1058-1060. (doi: 10.1016/j.neuron.2012.03.001) (PMID:22445333) (PMCID:PMC3353540)

2011

Capitão, L. , Sampaio, A. , Sampaio, C. , Vasconcelos, C. , Férnandez, M. , Garayzábal, E. , Shenton, M. E. and Gonçalves, Ó. F. (2011) MRI amygdala volume in Williams Syndrome. Research in Developmental Disabilities, 32(6), pp. 2767-2772. (doi: 10.1016/j.ridd.2011.05.033) (PMID:21752593)

This list was generated on Wed Sep 23 04:56:21 2020 BST.
Number of items: 18.

Articles

Barron, H. C. , Mars, R. B. , Dupret, D. , Lerch, J. and Sampaio-Baptista, C. (2020) Cross-species neuroscience: closing the explanatory gap. Philosophical Transactions of the Royal Society B: Biological Sciences, (Accepted for Publication)

Sampaio-Baptista, C. et al. (2020) White matter structure and myelin-related gene expression alterations with experience in adult rats. Progress in Neurobiology, 187, 101770. (doi: 10.1016/j.pneurobio.2020.101770) (PMID:32001310) (PMCID:PMC7086231)

Lazari, A. , Koudelka, S. and Sampaio-Baptista, C. (2018) Experience-related reductions of myelin and axon diameter in adulthood. Journal of Neurophysiology, 120(4), pp. 1772-1775. (doi: 10.1152/jn.00070.2018) (PMID:30207857) (PMCID:PMC6230794)

Neyedli, H. F. , Sampaio-Baptista, C. , Kirkman, M. A. , Havard, D. , Lührs, M. , Ramsden, K. , Flitney, D. D. , Clare, S. , Goebel, R. and Johansen-Berg, H. (2018) Increasing lateralized motor activity in younger and older adults using Real-time fMRI during executed movements. Neuroscience, 378, pp. 165-174. (doi: 10.1016/j.neuroscience.2017.02.010) (PMID:28214578) (PMCID:PMC5953409)

Huang, H. et al. (2018) Development of white matter microstructure in relation to verbal and visuospatial working memory—a longitudinal study. PLoS ONE, 13(4), e0195540. (doi: 10.1371/journal.pone.0195540) (PMID:29689058) (PMCID:PMC5916522)

Heath, F. , Hurley, S. A. , Johansen-Berg, H. and Sampaio-Baptista, C. (2018) Advances in noninvasive myelin imaging. Developmental Neurobiology, 78(2), pp. 136-151. (doi: 10.1002/dneu.22552) (PMID:29082667) (PMCID:PMC5813152)

Sampaio-Baptista, C. , Sanders, Z.-B. and Johansen-Berg, H. (2018) Structural plasticity in adulthood with motor learning and stroke rehabilitation. Annual Review of Neuroscience, 41, pp. 25-40. (doi: 10.1146/annurev-neuro-080317-062015) (PMID:29490196)

Sampaio-Baptista, C. and Johansen-Berg, H. (2017) White matter plasticity in the adult brain. Neuron, 96(6), pp. 1239-1251. (doi: 10.1016/j.neuron.2017.11.026) (PMID:29268094) (PMCID:PMC5766826)

Kaller, M. S. , Lazari, A. , Blanco-Duque, C. , Sampaio-Baptista, C. and Johansen-Berg, H. (2017) Myelin plasticity and behaviour — connecting the dots. Current Opinion in Neurobiology, 47, pp. 86-92. (doi: 10.1016/j.conb.2017.09.014) (PMID:29054040) (PMCID:PMC5844949)

Krogsrud, S. K. et al. (2016) Changes in white matter microstructure in the developing brain—a longitudinal diffusion tensor imaging study of children from 4 to 11 years of age. NeuroImage, 124(Part A), pp. 473-486. (doi: 10.1016/j.neuroimage.2015.09.017) (PMID:26375208) (PMCID:PMC4655940)

Sampaio-Baptista, C. , Filippini, N. , Stagg, C. J. , Near, J. , Scholz, J. and Johansen-Berg, H. (2015) Changes in functional connectivity and GABA levels with long-term motor learning. NeuroImage, 106, pp. 15-20. (doi: 10.1016/j.neuroimage.2014.11.032) (PMID:25463472) (PMCID:PMC4405007)

Sampaio-Baptista, C. , Scholz, J. , Jenkinson, M. , Thomas, A. G. , Filippini, N. , Smit, G. , Douaud, G. and Johansen-Berg, H. (2014) Gray matter volume is associated with rate of subsequent skill learning after a long term training intervention. NeuroImage, 96, pp. 158-166. (doi: 10.1016/j.neuroimage.2014.03.056) (PMID:24680712) (PMCID:PMC4075341)

Stagg, C. J. , Bachtiar, V. , Amadi, U. , Gudberg, C. A. , Ilie, A. S. , Sampaio-Baptista, C. , O'Shea, J. , Woolrich, M. and Smith, S. M. (2014) Local GABA concentration is related to network-level resting functional connectivity. eLife, 3, e01465. (doi: 10.7554/eLife.01465.001) (PMID:24668166) (PMCID:PMC3964822)

Banerjee, A. , González-Rueda, A. , Sampaio-Baptista, C. , Paulsen, O. and Rodríguez-Moreno, A. (2014) Distinct mechanisms of spike timing-dependent LTD at vertical and horizontal inputs onto L2/3 pyramidal neurons in mouse barrel cortex. Physiological Reports, 2(3), e00271. (doi: 10.1002/phy2.271) (PMID:24760524) (PMCID:PMC4002250)

Sampaio-Baptista, C. et al. (2013) Motor skill learning induces changes in white matter microstructure and myelination. Journal of Neuroscience, 33(50), pp. 19499-19503. (doi: 10.1523/JNEUROSCI.3048-13.2013) (PMID:24336716) (PMCID:PMC3858622)

Johansen-Berg, H. , Sampaio Baptista, C. and Thomas, A. G. (2012) Human structural plasticity at record speed. Neuron, 73(6), pp. 1058-1060. (doi: 10.1016/j.neuron.2012.03.001) (PMID:22445333) (PMCID:PMC3353540)

Capitão, L. , Sampaio, A. , Sampaio, C. , Vasconcelos, C. , Férnandez, M. , Garayzábal, E. , Shenton, M. E. and Gonçalves, Ó. F. (2011) MRI amygdala volume in Williams Syndrome. Research in Developmental Disabilities, 32(6), pp. 2767-2772. (doi: 10.1016/j.ridd.2011.05.033) (PMID:21752593)

Book Sections

Sampaio-Baptista, C. , Diosi, K. and Johnansen-Berg, H. (2019) Magnetic resonance techniques for imaging white matter. In: Lyons, D. A. and Kegel, L. (eds.) Oligodendrocytes: Methods and Protocols. Series: Methods in molecular biology (1936). Humana Press: New York, NY, pp. 397-407. ISBN 9781493990702 (doi:10.1007/978-1-4939-9072-6_22)

This list was generated on Wed Sep 23 04:56:21 2020 BST.