Professor Kevin Maloy
- Professor Mucosal Immunology (Immunology & Infection)
Publications
2024
Pearson, Claire F. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2024)
Update: Induction of inflammatory bowel disease in immunodeficient mice by injection of naïve CD4+ T cells (T cell transfer model of colitis).
Current Protocols, 4(7),
e1092.
(doi: 10.1002/cpz1.1092)
(PMID:39007482)
Heuberger, C.E. et al. (2024) MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses. Mucosal Immunology, 17(3), pp. 416-430. (doi: 10.1016/j.mucimm.2023.05.001) (PMID:37209960)
2022
Forster, S. C. et al. (2022) Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis. Nature Microbiology, 7(4), pp. 590-599. (doi: 10.1038/s41564-022-01094-z) (PMID:35365791) (PMCID:PMC8975739)
Yogev, N. et al. (2022) CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survival. Cell Reports, 38(13), 110565. (doi: 10.1016/j.celrep.2022.110565) (PMID:35354043)
2021
Heuberger, Cornelia, Pott, Johanna and Maloy, Kevin Joseph ORCID: https://orcid.org/0000-0001-5795-7688
(2021)
Why do intestinal epithelial cells express MHC class II?
Immunology, 162(4),
pp. 357-367.
(doi: 10.1111/imm.13270)
(PMID:32966619)
(PMCID:PMC7968399)
dos Santos, Luara Isabela, Torres, Thais Abdala, DIniz, Suelen Queiroz, Gonçalves, Ricardo, Caballero-Flores, Gustavo, Núñez, Gabriel, Gazzinelli, Richardo Tostes, Maloy, Kevin Joseph ORCID: https://orcid.org/0000-0001-5795-7688 and Antonelli, Lis Ribeiro do V.
(2021)
Disrupted iron metabolism and mortality during co-infection with malaria and an intestinal gram-negative extracellular pathogen.
Cell Reports, 34(2),
108613.
(doi: 10.1016/j.celrep.2020.108613)
(PMID:33440153)
(PMCID:PMC8655499)
2020
Abeler-Dörner, L. et al. (2020) High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation. Nature Immunology, 21(1), pp. 86-100. (doi: 10.1038/s41590-019-0549-0) (PMID:31844327)
Ahern, Philip P. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2020)
Understanding immune–microbiota interactions in the intestine.
Immunology, 159(1),
pp. 4-14.
(doi: 10.1111/imm.13150)
(PMID:31777071)
2018
Costa, Pedro A.C., Figueiredo, Maria M., Diniz, Suelen Q., Peixoto, Ana P.M.M., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Teixeira-Carvalho, Andrea, Tada, Mauro S., Pereira, Dhelio B., Gazzinelli, Ricardo T. and Antonelli, Lis R.V.
(2018)
Plasmodium vivax infection impairs regulatory T-Cell suppressive function during acute malaria.
Journal of Infectious Diseases, 218(8),
pp. 1314-1323.
(doi: 10.1093/infdis/jiy296)
(PMID:29800313)
(PMCID:PMC6129110)
Murphy, Alison G. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Defens-IN! human α-defensin 5 acts as an unwitting double agent to promote Shigella infection.
Immunity, 48(6),
pp. 1070-1072.
(doi: 10.1016/j.immuni.2018.05.015)
(PMID:29924970)
Pott, Johanna, Kabat, Agnieszka Martyna and Maloy, Kevin Joseph ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Intestinal epithelial cell autophagy is required to protect against TNF-induced apoptosis during chronic colitis in mice.
Cell Host and Microbe, 23(2),
191-202.e4.
(doi: 10.1016/j.chom.2017.12.017)
(PMID:29358084)
De Cicco, Paola, Sanders, Theodore, Cirino, Giuseppe, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Ianaro, Angela
(2018)
Hydrogen sulfide reduces myeloid-derived suppressor cell-mediated inflammatory response in a model of Helicobacter hepaticus-induced colitis.
Frontiers in Immunology, 9,
499.
(doi: 10.3389/fimmu.2018.00499)
(PMID:29636751)
(PMCID:PMC5880908)
Dumitru, Cristina, Kabat, Agnieszka M. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Metabolic adaptations of CD4+ T Cells in inflammatory disease.
Frontiers in Immunology, 9,
540.
(doi: 10.3389/fimmu.2018.00540)
(PMID:29599783)
(PMCID:PMC5862799)
Pott, Johanna and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Epithelial autophagy controls chronic colitis by reducing TNF-induced apoptosis.
Autophagy, 14(8),
pp. 1460-1461.
(doi: 10.1080/15548627.2018.1450021)
(PMID:29799774)
(PMCID:PMC6103553)
2017
Lei-Leston, Andrea, Murphy, Alison G. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2017)
Epithelial cell inflammasomes in intestinal immunity and inflammation.
Frontiers in Immunology, 8,
1168.
(doi: 10.3389/fimmu.2017.01168)
(PMID:28979266)
(PMCID:PMC5611393)
West, N. R. et al. (2017) Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease. Nature Medicine, 23(5), pp. 579-589. (doi: 10.1038/nm.4307) (PMID:28368383) (PMCID:PMC5420447)
Sanders, Theodore J., Yrlid, Ulf and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2017)
Intestinal mononuclear phagocytes in health and disease.
Microbiology Spectrum, 5(1),
MCHD0047-2.
(doi: 10.1128/microbiolspec.mchd-0047-2016)
(PMID:28102120)
2016
Lei, Andrea and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2016)
Colon cancer in the land of NOD: NLRX1 as an intrinsic tumor suppressor.
Trends in Immunology, 37(9),
pp. 569-570.
(doi: 10.1016/j.it.2016.07.004)
(PMID:27452288)
Kabat, Agnieszka M., Pott, Johanna and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2016)
The mucosal immune system and its regulation by autophagy.
Frontiers in Immunology, 7,
240.
(doi: 10.3389/fimmu.2016.00240)
(PMID:27446072)
(PMCID:PMC4916208)
Pott, Johanna, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Izcue, Ana
(2016)
Barrier regulation: tolerance stops at cell death.
Nature Immunology, 17,
pp. 349-350.
(doi: 10.1038/ni.3418)
(PMID:27002834)
Kabat, A. M. et al. (2016) The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. eLife, 5, e12444. (doi: 10.7554/elife.12444) (PMID:26910010) (PMCID:PMC4798959)
2015
Harrison, O.J., Srinivasan, N., Pott, J., Schiering, C., Krausgruber, T., Ilott, N.E. and Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688
(2015)
Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3+ Treg cell function in the intestine.
Mucosal Immunology, 8,
pp. 1226-1236.
(doi: 10.1038/mi.2015.13)
(PMID:25736457)
(PMCID:PMC4368110)
Sellin, Mikael E., Maslwowski, Kendle M., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Hardt, Wolf-Dietrich
(2015)
Inflammasomes of the intestinal epithelium.
Trends in Immunology, 36(8),
pp. 442-450.
(doi: 10.1016/j.it.2015.06.002)
(PMID:26166583)
2014
Kabat, Agnieszka M., Srinivasan, Naren and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Modulation of immune development and function by intestinal microbiota.
Trends in Immunology, 35(11),
pp. 507-517.
(doi: 10.1016/j.it.2014.07.010)
(PMID:25172617)
(PMCID:PMC6485503)
Nordlander, S., Pott, J. and Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen.
Mucosal Immunology, 7,
pp. 775-785.
(doi: 10.1038/mi.2013.95)
(PMID:24280936)
(PMCID:PMC4020766)
Song-Zhao, G.X., Srinivasan, N., Pott, J., Baban, D., Frankel, G. and Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen.
Mucosal Immunology, 7,
pp. 763-774.
(doi: 10.1038/mi.2013.94)
(PMID:24280937)
(PMCID:PMC4048180)
Kole, Abhisake and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Control of intestinal inflammation by interleukin-10.
In: Fillatreau, Simon and O'Garra, Anne (eds.)
Interleukin-10 in Health and Disease.
Series: Current topics in microbiology and immunology (380).
Springer: Heidelberg, pp. 19-38.
ISBN 9783662434918
(doi: 10.1007/978-3-662-43492-5_2)
Song-Zhao, George X. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Experimental mouse models of T cell-dependent inflammatory bowel disease.
In: Waisman, Ari and Becher, Burkhard (eds.)
T-Helper Cells: Methods and Protocols.
Series: Methods in molecular biology (1193).
Humana Press: New York, NY, pp. 199-211.
ISBN 9781493912117
(doi: 10.1007/978-1-4939-1212-4_18)
2013
Brain, O. et al. (2013) The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. Immunity, 39(3), pp. 521-536. (doi: 10.1016/j.immuni.2013.08.035) (PMID:24054330)
Kole, Abhisake, He, JianPing, Rivollier, Aymeric, Silveira, Danielle D., Kitamura, Kazuya, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Kelsall, Brian L.
(2013)
Type I IFNs regulate effector and regulatory T cell accumulation and anti-Inflammatory cytokine production during T cell–mediated colitis.
Journal of Immunology, 191(5),
pp. 2771-2779.
(doi: 10.4049/jimmunol.1301093)
(PMID:23913971)
(PMCID:PMC3896249)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Uhlig, Holm H.
(2013)
ILC1 populations join the border patrol.
Immunity, 38(4),
pp. 630-632.
(doi: 10.1016/j.immuni.2013.03.005)
(PMID:23601681)
2012
Coccia, Margherita, Harrison, Oliver J., Schiering, Chris, Asquith, Mark J., Becher, Burkhard, Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2012)
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+Th17 cells.
Journal of Experimental Medicine, 209(9),
pp. 1595-1609.
(doi: 10.1084/jem.20111453)
(PMID:22891275)
(PMCID:PMC3428945)
Boulard, Olivier, Kirchberger, Stefanie, Royston, Daniel J., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona M.
(2012)
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
Journal of Experimental Medicine, 209(7),
pp. 1309-1324.
(doi: 10.1084/jem.20120239)
(PMID:22734048)
(PMCID:PMC3405508)
2011
Harrison, Oliver J. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2011)
Innate immune activation in intestinal homeostasis.
Journal of Innate Immunity, 3(6),
pp. 585-593.
(doi: 10.1159/000330913)
(PMID:21912101)
(PMCID:PMC3224517)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2011)
Intestinal homeostasis and its breakdown in inflammatory bowel disease.
Nature, 474(7351),
pp. 298-306.
(doi: 10.1038/nature10208)
(PMID:21677746)
2010
Ahern, Philip P., Schiering, Chris, Buonocore, Sofia, McGeachy, Mandy J., Cua, Dan J., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2010)
Interleukin-23 drives intestinal inflammation through direct activity on T cells.
Immunity, 33(2),
pp. 279-288.
(doi: 10.1016/j.immuni.2010.08.010)
(PMID:20732640)
(PMCID:PMC3078329)
Asquith, Mark J., Boulard, Olivier, Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2010)
Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.
Gastroenterology, 139(2),
519-529.e2.
(doi: 10.1053/j.gastro.2010.04.045)
(PMID:20433840)
(PMCID:PMC3739016)
Buonocore, Sofia, Ahern, Philip A., Uhlig, Holm H., Ivanov, Ivaylo I., Littman, Dan R., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2010)
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.
Nature, 464(7293),
pp. 1371-1375.
(doi: 10.1038/nature08949)
(PMID:20393462)
(PMCID:PMC3796764)
Boulard, Olivier, Asquith, Mark J., Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2010)
TLR2-independent induction and regulation of chronic intestinal inflammation.
European Journal of Immunology, 40(2),
pp. 516-524.
(doi: 10.1002/eji.200939669)
(PMID:19950179)
(PMCID:PMC3812679)
2008
Ahern, Philip P., Izcue, Ana, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2008)
The interleukin-23 axis in intestinal inflammation.
Immunological Reviews, 226(1),
pp. 147-159.
(doi: 10.1111/j.1600-065x.2008.00705.x)
(PMID:19161422)
Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688 and Kullberg, M.C.
(2008)
IL-23 and Th17 cytokines in intestinal homeostasis.
Mucosal Immunology, 1(5),
pp. 339-349.
(doi: 10.1038/mi.2008.28)
(PMID:19079198)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2008)
The interleukin-23 / interleukin-17 axis in intestinal inflammation.
Journal of Internal Medicine, 263(6),
pp. 584-590.
(doi: 10.1111/j.1365-2796.2008.01950.x)
(PMID:18479257)
Izcue, Ana, Hue, Sophie, Buonocore, Sofia, Arancibia-Cárcamo, Carolina V., Ahern, Philip P., Iwakura, Yoichiro, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2008)
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.
Immunity, 28(4),
pp. 559-570.
(doi: 10.1016/j.immuni.2008.02.019)
(PMID:18400195)
(PMCID:PMC2292821)
2007
Coombes, Janine L. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2007)
Control of intestinal homeostasis by regulatory T cells and dendritic cells.
Seminars in Immunology, 19(2),
pp. 116-126.
(doi: 10.1016/j.smim.2007.01.001)
(PMID:17320411)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2007)
Induction and regulation of inflammatory bowel disease in immunodeficient mice by distinct CD4+ T-cell subsets.
In: Fairchild, Paul J. (ed.)
Immunological Tolerance: Methods and Protocols.
Series: Methods in molecular biology (380).
Humana Press: Totowa, N.J., pp. 327-335.
ISBN 9781588296528
(doi: 10.1007/978-1-59745-395-0_19)
2006
Hue, Sophie, Ahern, Philip, Buonocore, Sofia, Kullberg, Marika C., Cua, Daniel J., McKenzie, Brent S., Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2006)
Interleukin-23 drives innate and T cell-mediated intestinal inflammation.
Journal of Experimental Medicine, 203(11),
pp. 2473-2483.
(doi: 10.1084/jem.20061099)
(PMID:17030949)
(PMCID:PMC2118132)
Kullberg, M. C. et al. (2006) IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. Journal of Experimental Medicine, 203(11), pp. 2485-2494. (doi: 10.1084/jem.20061082) (PMID:17030948) (PMCID:PMC2118119)
Heinzerling, Lucie, Basch, Veronique, Maloy, Kevin ORCID: https://orcid.org/0000-0001-5795-7688, Johansen, Pål, Senti, Gabriela, Wüthrich, Brunello, Storni, Tazio and Kündig, Thomas M.
(2006)
Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses.
Vaccine, 24(9),
pp. 1389-1394.
(doi: 10.1016/j.vaccine.2005.09.018)
(PMID:16225968)
2005
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2005)
Fueling regulation: IL-2 keeps CD4+ Treg cells fit.
Nature Immunology, 6(11),
pp. 1071-1072.
(doi: 10.1038/ni1105-1071)
(PMID:16239920)
Coombes, Janine L., Robinson, Nicholas J., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Uhlig, Holm H. and Powrie, Fiona
(2005)
Regulatory T cells and intestinal homeostasis.
Immunological Reviews, 204(1),
pp. 184-194.
(doi: 10.1111/j.0105-2896.2005.00250.x)
(PMID:15790359)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Antonelli, Lis R.V., Lefevre, Marie and Powrie, Fiona
(2005)
Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells.
Immunology Letters, 97(2),
pp. 189-192.
(doi: 10.1016/j.imlet.2005.01.004)
(PMID:15752557)
Johansen, P. et al. (2005) Direct intralymphatic injection of peptide vaccines enhances immunogenicity. European Journal of Immunology, 35(2), pp. 568-574. (doi: 10.1002/eji.200425599) (PMID:15682446)
2003
Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2003)
Regulating the regulators.
Science, 299(5609),
pp. 1030-1031.
(doi: 10.1126/science.1082031)
(PMID:12586934)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Salaun, Laurence, Cahill, Rachel, Dougan, Gordon, Saunders, Nigel J. and Powrie, Fiona
(2003)
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms.
Journal of Experimental Medicine, 197(1),
pp. 111-119.
(doi: 10.1084/jem.20021345)
(PMID:12515818)
(PMCID:PMC2193798)
2001
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2001)
Regulatory T cells in the control of immune pathology.
Nature Immunology, 2(9),
pp. 816-822.
(doi: 10.1038/ni0901-816)
(PMID:11526392)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Erdmann, Iris, Basch, Veronique, Sierro, Sophie, Kramps, Thomas A., Zinkernagel, Rolf M., Oehen, Stegan and Kündig, Thomas M.
(2001)
Intralymphatic immunization enhances DNA vaccination.
Proceedings of the National Academy of Sciences of the United States of America, 98(6),
pp. 3299-3303.
(doi: 10.1073/pnas.051630798)
(PMID:11248073)
(PMCID:PMC30648)
2000
Senn, Karin A., McCoy, Kathy D., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Stark, Gerlinde, Fröhli, Erika, Rülicke, Thomas and Klemenz, Roman
(2000)
T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis.
European Journal of Immunology, 30(7),
pp. 1929-1938.
(doi: 10.1002/1521-4141(200007)30:7<1929::AID-IMMU1929>3.0.CO;2-1)
(PMID:10940882)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Burkhart, Christoph, Junt, Tobias M., Odermatt, Bernhard, Oxenius, Annette, Piali, Luca, Zinkernagel, Rolf M. and Hengartner, Hans
(2000)
CD4(+) T cell subsets during virus infection: protective capacity depends on effector cytokine secretion and on migratory capability.
Journal of Experimental Medicine, 191(12),
pp. 2159-2170.
(doi: 10.1084/jem.191.12.2159)
(PMID:10859340)
(PMCID:PMC2193195)
Ludewig, Burkhard, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, López‐Macías, Constantino, Odermatt, Bernhard, Hengartner, Hans and Zinkernagel, Rolf M.
(2000)
Induction of optimal anti-viral neutralizing B cell responses by dendritic cells requires transport and release of virus particles in secondary lymphoid organs.
European Journal of Immunology, 30(1),
pp. 185-196.
(doi: 10.1002/1521-4141(200001)30:1<185::AID-IMMU185>3.0.CO;2-L)
(PMID:10602040)
1999
Maloy, K. J. et al. (1999) Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection. Journal of Immunology, 162(5), pp. 2867-2874. (PMID:10072535)
Steinhoff, U., Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Burkhart, C., Clark, A.J., Rülicke, T., Hengartner, H. and Zinkernagel, R.M.
(1999)
Variable immune response against a developmentally regulated self-antigen.
Journal of Autoimmunity, 12(1),
pp. 27-34.
(doi: 10.1006/jaut.1998.0254)
(PMID:10028019)
1998
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Odermatt, Bernhard, Hengartner, Hans and Zinkernagel, Rolf M.
(1998)
Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection.
Proceedings of the National Academy of Sciences of the United States of America, 95(3),
pp. 1160-1165.
(doi: 10.1073/pnas.95.3.1160)
(PMID:9448302)
(PMCID:PMC18706)
1995
O'Hagan, D.T., Jeffery, H., Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Mowat, A.M., Rahman, D. and Challacombe, S.J.
(1995)
Biodegradable microparticles as oral vaccines.
Advances in Experimental Medicine and Biology, 371B,
pp. 1463-1467.
(PMID:7502838)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Donachie, Anne M. and Mowat, Allan M.
(1995)
Induction of Th1 and Th2 CD4+ T cell responses by oral or parenteral immunization with ISCOMS.
European Journal of Immunology, 25(10),
pp. 2835-2841.
(doi: 10.1002/eji.1830251019)
(PMID:7589080)
1994
Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Donachie, A.M., O'Hagan, D.T. and Mowat, A.M.
(1994)
Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles.
Immunology, 81(4),
pp. 661-667.
(PMID:7518802)
1993
Mowat, A.M., Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688 and Donachie, A.M.
(1993)
Immune-stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunization with protein antigens.
Immunology, 80(4),
pp. 527-534.
(PMID:7508416)
(PMCID:PMC1422256)
1991
Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Mowat, A. McI., Zamoyska, R. and Crispe, I.N.
(1991)
Phenotypic heterogeneity of intraepithelial T lymphocytes from mouse small intestine.
Immunology, 72(4),
pp. 555-562.
(PMID:2037315)
(PMCID:PMC1384377)
Articles
Pearson, Claire F. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2024)
Update: Induction of inflammatory bowel disease in immunodeficient mice by injection of naïve CD4+ T cells (T cell transfer model of colitis).
Current Protocols, 4(7),
e1092.
(doi: 10.1002/cpz1.1092)
(PMID:39007482)
Heuberger, C.E. et al. (2024) MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses. Mucosal Immunology, 17(3), pp. 416-430. (doi: 10.1016/j.mucimm.2023.05.001) (PMID:37209960)
Forster, S. C. et al. (2022) Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis. Nature Microbiology, 7(4), pp. 590-599. (doi: 10.1038/s41564-022-01094-z) (PMID:35365791) (PMCID:PMC8975739)
Yogev, N. et al. (2022) CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survival. Cell Reports, 38(13), 110565. (doi: 10.1016/j.celrep.2022.110565) (PMID:35354043)
Heuberger, Cornelia, Pott, Johanna and Maloy, Kevin Joseph ORCID: https://orcid.org/0000-0001-5795-7688
(2021)
Why do intestinal epithelial cells express MHC class II?
Immunology, 162(4),
pp. 357-367.
(doi: 10.1111/imm.13270)
(PMID:32966619)
(PMCID:PMC7968399)
dos Santos, Luara Isabela, Torres, Thais Abdala, DIniz, Suelen Queiroz, Gonçalves, Ricardo, Caballero-Flores, Gustavo, Núñez, Gabriel, Gazzinelli, Richardo Tostes, Maloy, Kevin Joseph ORCID: https://orcid.org/0000-0001-5795-7688 and Antonelli, Lis Ribeiro do V.
(2021)
Disrupted iron metabolism and mortality during co-infection with malaria and an intestinal gram-negative extracellular pathogen.
Cell Reports, 34(2),
108613.
(doi: 10.1016/j.celrep.2020.108613)
(PMID:33440153)
(PMCID:PMC8655499)
Abeler-Dörner, L. et al. (2020) High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation. Nature Immunology, 21(1), pp. 86-100. (doi: 10.1038/s41590-019-0549-0) (PMID:31844327)
Ahern, Philip P. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2020)
Understanding immune–microbiota interactions in the intestine.
Immunology, 159(1),
pp. 4-14.
(doi: 10.1111/imm.13150)
(PMID:31777071)
Costa, Pedro A.C., Figueiredo, Maria M., Diniz, Suelen Q., Peixoto, Ana P.M.M., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Teixeira-Carvalho, Andrea, Tada, Mauro S., Pereira, Dhelio B., Gazzinelli, Ricardo T. and Antonelli, Lis R.V.
(2018)
Plasmodium vivax infection impairs regulatory T-Cell suppressive function during acute malaria.
Journal of Infectious Diseases, 218(8),
pp. 1314-1323.
(doi: 10.1093/infdis/jiy296)
(PMID:29800313)
(PMCID:PMC6129110)
Murphy, Alison G. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Defens-IN! human α-defensin 5 acts as an unwitting double agent to promote Shigella infection.
Immunity, 48(6),
pp. 1070-1072.
(doi: 10.1016/j.immuni.2018.05.015)
(PMID:29924970)
Pott, Johanna, Kabat, Agnieszka Martyna and Maloy, Kevin Joseph ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Intestinal epithelial cell autophagy is required to protect against TNF-induced apoptosis during chronic colitis in mice.
Cell Host and Microbe, 23(2),
191-202.e4.
(doi: 10.1016/j.chom.2017.12.017)
(PMID:29358084)
De Cicco, Paola, Sanders, Theodore, Cirino, Giuseppe, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Ianaro, Angela
(2018)
Hydrogen sulfide reduces myeloid-derived suppressor cell-mediated inflammatory response in a model of Helicobacter hepaticus-induced colitis.
Frontiers in Immunology, 9,
499.
(doi: 10.3389/fimmu.2018.00499)
(PMID:29636751)
(PMCID:PMC5880908)
Dumitru, Cristina, Kabat, Agnieszka M. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Metabolic adaptations of CD4+ T Cells in inflammatory disease.
Frontiers in Immunology, 9,
540.
(doi: 10.3389/fimmu.2018.00540)
(PMID:29599783)
(PMCID:PMC5862799)
Pott, Johanna and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2018)
Epithelial autophagy controls chronic colitis by reducing TNF-induced apoptosis.
Autophagy, 14(8),
pp. 1460-1461.
(doi: 10.1080/15548627.2018.1450021)
(PMID:29799774)
(PMCID:PMC6103553)
Lei-Leston, Andrea, Murphy, Alison G. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2017)
Epithelial cell inflammasomes in intestinal immunity and inflammation.
Frontiers in Immunology, 8,
1168.
(doi: 10.3389/fimmu.2017.01168)
(PMID:28979266)
(PMCID:PMC5611393)
West, N. R. et al. (2017) Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease. Nature Medicine, 23(5), pp. 579-589. (doi: 10.1038/nm.4307) (PMID:28368383) (PMCID:PMC5420447)
Sanders, Theodore J., Yrlid, Ulf and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2017)
Intestinal mononuclear phagocytes in health and disease.
Microbiology Spectrum, 5(1),
MCHD0047-2.
(doi: 10.1128/microbiolspec.mchd-0047-2016)
(PMID:28102120)
Lei, Andrea and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2016)
Colon cancer in the land of NOD: NLRX1 as an intrinsic tumor suppressor.
Trends in Immunology, 37(9),
pp. 569-570.
(doi: 10.1016/j.it.2016.07.004)
(PMID:27452288)
Kabat, Agnieszka M., Pott, Johanna and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2016)
The mucosal immune system and its regulation by autophagy.
Frontiers in Immunology, 7,
240.
(doi: 10.3389/fimmu.2016.00240)
(PMID:27446072)
(PMCID:PMC4916208)
Pott, Johanna, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Izcue, Ana
(2016)
Barrier regulation: tolerance stops at cell death.
Nature Immunology, 17,
pp. 349-350.
(doi: 10.1038/ni.3418)
(PMID:27002834)
Kabat, A. M. et al. (2016) The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. eLife, 5, e12444. (doi: 10.7554/elife.12444) (PMID:26910010) (PMCID:PMC4798959)
Harrison, O.J., Srinivasan, N., Pott, J., Schiering, C., Krausgruber, T., Ilott, N.E. and Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688
(2015)
Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3+ Treg cell function in the intestine.
Mucosal Immunology, 8,
pp. 1226-1236.
(doi: 10.1038/mi.2015.13)
(PMID:25736457)
(PMCID:PMC4368110)
Sellin, Mikael E., Maslwowski, Kendle M., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Hardt, Wolf-Dietrich
(2015)
Inflammasomes of the intestinal epithelium.
Trends in Immunology, 36(8),
pp. 442-450.
(doi: 10.1016/j.it.2015.06.002)
(PMID:26166583)
Kabat, Agnieszka M., Srinivasan, Naren and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Modulation of immune development and function by intestinal microbiota.
Trends in Immunology, 35(11),
pp. 507-517.
(doi: 10.1016/j.it.2014.07.010)
(PMID:25172617)
(PMCID:PMC6485503)
Nordlander, S., Pott, J. and Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen.
Mucosal Immunology, 7,
pp. 775-785.
(doi: 10.1038/mi.2013.95)
(PMID:24280936)
(PMCID:PMC4020766)
Song-Zhao, G.X., Srinivasan, N., Pott, J., Baban, D., Frankel, G. and Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen.
Mucosal Immunology, 7,
pp. 763-774.
(doi: 10.1038/mi.2013.94)
(PMID:24280937)
(PMCID:PMC4048180)
Brain, O. et al. (2013) The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. Immunity, 39(3), pp. 521-536. (doi: 10.1016/j.immuni.2013.08.035) (PMID:24054330)
Kole, Abhisake, He, JianPing, Rivollier, Aymeric, Silveira, Danielle D., Kitamura, Kazuya, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Kelsall, Brian L.
(2013)
Type I IFNs regulate effector and regulatory T cell accumulation and anti-Inflammatory cytokine production during T cell–mediated colitis.
Journal of Immunology, 191(5),
pp. 2771-2779.
(doi: 10.4049/jimmunol.1301093)
(PMID:23913971)
(PMCID:PMC3896249)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Uhlig, Holm H.
(2013)
ILC1 populations join the border patrol.
Immunity, 38(4),
pp. 630-632.
(doi: 10.1016/j.immuni.2013.03.005)
(PMID:23601681)
Coccia, Margherita, Harrison, Oliver J., Schiering, Chris, Asquith, Mark J., Becher, Burkhard, Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2012)
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+Th17 cells.
Journal of Experimental Medicine, 209(9),
pp. 1595-1609.
(doi: 10.1084/jem.20111453)
(PMID:22891275)
(PMCID:PMC3428945)
Boulard, Olivier, Kirchberger, Stefanie, Royston, Daniel J., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona M.
(2012)
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
Journal of Experimental Medicine, 209(7),
pp. 1309-1324.
(doi: 10.1084/jem.20120239)
(PMID:22734048)
(PMCID:PMC3405508)
Harrison, Oliver J. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2011)
Innate immune activation in intestinal homeostasis.
Journal of Innate Immunity, 3(6),
pp. 585-593.
(doi: 10.1159/000330913)
(PMID:21912101)
(PMCID:PMC3224517)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2011)
Intestinal homeostasis and its breakdown in inflammatory bowel disease.
Nature, 474(7351),
pp. 298-306.
(doi: 10.1038/nature10208)
(PMID:21677746)
Ahern, Philip P., Schiering, Chris, Buonocore, Sofia, McGeachy, Mandy J., Cua, Dan J., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2010)
Interleukin-23 drives intestinal inflammation through direct activity on T cells.
Immunity, 33(2),
pp. 279-288.
(doi: 10.1016/j.immuni.2010.08.010)
(PMID:20732640)
(PMCID:PMC3078329)
Asquith, Mark J., Boulard, Olivier, Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2010)
Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.
Gastroenterology, 139(2),
519-529.e2.
(doi: 10.1053/j.gastro.2010.04.045)
(PMID:20433840)
(PMCID:PMC3739016)
Buonocore, Sofia, Ahern, Philip A., Uhlig, Holm H., Ivanov, Ivaylo I., Littman, Dan R., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2010)
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.
Nature, 464(7293),
pp. 1371-1375.
(doi: 10.1038/nature08949)
(PMID:20393462)
(PMCID:PMC3796764)
Boulard, Olivier, Asquith, Mark J., Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2010)
TLR2-independent induction and regulation of chronic intestinal inflammation.
European Journal of Immunology, 40(2),
pp. 516-524.
(doi: 10.1002/eji.200939669)
(PMID:19950179)
(PMCID:PMC3812679)
Ahern, Philip P., Izcue, Ana, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2008)
The interleukin-23 axis in intestinal inflammation.
Immunological Reviews, 226(1),
pp. 147-159.
(doi: 10.1111/j.1600-065x.2008.00705.x)
(PMID:19161422)
Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688 and Kullberg, M.C.
(2008)
IL-23 and Th17 cytokines in intestinal homeostasis.
Mucosal Immunology, 1(5),
pp. 339-349.
(doi: 10.1038/mi.2008.28)
(PMID:19079198)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2008)
The interleukin-23 / interleukin-17 axis in intestinal inflammation.
Journal of Internal Medicine, 263(6),
pp. 584-590.
(doi: 10.1111/j.1365-2796.2008.01950.x)
(PMID:18479257)
Izcue, Ana, Hue, Sophie, Buonocore, Sofia, Arancibia-Cárcamo, Carolina V., Ahern, Philip P., Iwakura, Yoichiro, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2008)
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.
Immunity, 28(4),
pp. 559-570.
(doi: 10.1016/j.immuni.2008.02.019)
(PMID:18400195)
(PMCID:PMC2292821)
Coombes, Janine L. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2007)
Control of intestinal homeostasis by regulatory T cells and dendritic cells.
Seminars in Immunology, 19(2),
pp. 116-126.
(doi: 10.1016/j.smim.2007.01.001)
(PMID:17320411)
Hue, Sophie, Ahern, Philip, Buonocore, Sofia, Kullberg, Marika C., Cua, Daniel J., McKenzie, Brent S., Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2006)
Interleukin-23 drives innate and T cell-mediated intestinal inflammation.
Journal of Experimental Medicine, 203(11),
pp. 2473-2483.
(doi: 10.1084/jem.20061099)
(PMID:17030949)
(PMCID:PMC2118132)
Kullberg, M. C. et al. (2006) IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. Journal of Experimental Medicine, 203(11), pp. 2485-2494. (doi: 10.1084/jem.20061082) (PMID:17030948) (PMCID:PMC2118119)
Heinzerling, Lucie, Basch, Veronique, Maloy, Kevin ORCID: https://orcid.org/0000-0001-5795-7688, Johansen, Pål, Senti, Gabriela, Wüthrich, Brunello, Storni, Tazio and Kündig, Thomas M.
(2006)
Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses.
Vaccine, 24(9),
pp. 1389-1394.
(doi: 10.1016/j.vaccine.2005.09.018)
(PMID:16225968)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2005)
Fueling regulation: IL-2 keeps CD4+ Treg cells fit.
Nature Immunology, 6(11),
pp. 1071-1072.
(doi: 10.1038/ni1105-1071)
(PMID:16239920)
Coombes, Janine L., Robinson, Nicholas J., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Uhlig, Holm H. and Powrie, Fiona
(2005)
Regulatory T cells and intestinal homeostasis.
Immunological Reviews, 204(1),
pp. 184-194.
(doi: 10.1111/j.0105-2896.2005.00250.x)
(PMID:15790359)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Antonelli, Lis R.V., Lefevre, Marie and Powrie, Fiona
(2005)
Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells.
Immunology Letters, 97(2),
pp. 189-192.
(doi: 10.1016/j.imlet.2005.01.004)
(PMID:15752557)
Johansen, P. et al. (2005) Direct intralymphatic injection of peptide vaccines enhances immunogenicity. European Journal of Immunology, 35(2), pp. 568-574. (doi: 10.1002/eji.200425599) (PMID:15682446)
Powrie, Fiona and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2003)
Regulating the regulators.
Science, 299(5609),
pp. 1030-1031.
(doi: 10.1126/science.1082031)
(PMID:12586934)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Salaun, Laurence, Cahill, Rachel, Dougan, Gordon, Saunders, Nigel J. and Powrie, Fiona
(2003)
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms.
Journal of Experimental Medicine, 197(1),
pp. 111-119.
(doi: 10.1084/jem.20021345)
(PMID:12515818)
(PMCID:PMC2193798)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688 and Powrie, Fiona
(2001)
Regulatory T cells in the control of immune pathology.
Nature Immunology, 2(9),
pp. 816-822.
(doi: 10.1038/ni0901-816)
(PMID:11526392)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Erdmann, Iris, Basch, Veronique, Sierro, Sophie, Kramps, Thomas A., Zinkernagel, Rolf M., Oehen, Stegan and Kündig, Thomas M.
(2001)
Intralymphatic immunization enhances DNA vaccination.
Proceedings of the National Academy of Sciences of the United States of America, 98(6),
pp. 3299-3303.
(doi: 10.1073/pnas.051630798)
(PMID:11248073)
(PMCID:PMC30648)
Senn, Karin A., McCoy, Kathy D., Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Stark, Gerlinde, Fröhli, Erika, Rülicke, Thomas and Klemenz, Roman
(2000)
T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis.
European Journal of Immunology, 30(7),
pp. 1929-1938.
(doi: 10.1002/1521-4141(200007)30:7<1929::AID-IMMU1929>3.0.CO;2-1)
(PMID:10940882)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Burkhart, Christoph, Junt, Tobias M., Odermatt, Bernhard, Oxenius, Annette, Piali, Luca, Zinkernagel, Rolf M. and Hengartner, Hans
(2000)
CD4(+) T cell subsets during virus infection: protective capacity depends on effector cytokine secretion and on migratory capability.
Journal of Experimental Medicine, 191(12),
pp. 2159-2170.
(doi: 10.1084/jem.191.12.2159)
(PMID:10859340)
(PMCID:PMC2193195)
Ludewig, Burkhard, Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, López‐Macías, Constantino, Odermatt, Bernhard, Hengartner, Hans and Zinkernagel, Rolf M.
(2000)
Induction of optimal anti-viral neutralizing B cell responses by dendritic cells requires transport and release of virus particles in secondary lymphoid organs.
European Journal of Immunology, 30(1),
pp. 185-196.
(doi: 10.1002/1521-4141(200001)30:1<185::AID-IMMU185>3.0.CO;2-L)
(PMID:10602040)
Maloy, K. J. et al. (1999) Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection. Journal of Immunology, 162(5), pp. 2867-2874. (PMID:10072535)
Steinhoff, U., Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Burkhart, C., Clark, A.J., Rülicke, T., Hengartner, H. and Zinkernagel, R.M.
(1999)
Variable immune response against a developmentally regulated self-antigen.
Journal of Autoimmunity, 12(1),
pp. 27-34.
(doi: 10.1006/jaut.1998.0254)
(PMID:10028019)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Odermatt, Bernhard, Hengartner, Hans and Zinkernagel, Rolf M.
(1998)
Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection.
Proceedings of the National Academy of Sciences of the United States of America, 95(3),
pp. 1160-1165.
(doi: 10.1073/pnas.95.3.1160)
(PMID:9448302)
(PMCID:PMC18706)
O'Hagan, D.T., Jeffery, H., Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Mowat, A.M., Rahman, D. and Challacombe, S.J.
(1995)
Biodegradable microparticles as oral vaccines.
Advances in Experimental Medicine and Biology, 371B,
pp. 1463-1467.
(PMID:7502838)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688, Donachie, Anne M. and Mowat, Allan M.
(1995)
Induction of Th1 and Th2 CD4+ T cell responses by oral or parenteral immunization with ISCOMS.
European Journal of Immunology, 25(10),
pp. 2835-2841.
(doi: 10.1002/eji.1830251019)
(PMID:7589080)
Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Donachie, A.M., O'Hagan, D.T. and Mowat, A.M.
(1994)
Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles.
Immunology, 81(4),
pp. 661-667.
(PMID:7518802)
Mowat, A.M., Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688 and Donachie, A.M.
(1993)
Immune-stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunization with protein antigens.
Immunology, 80(4),
pp. 527-534.
(PMID:7508416)
(PMCID:PMC1422256)
Maloy, K.J. ORCID: https://orcid.org/0000-0001-5795-7688, Mowat, A. McI., Zamoyska, R. and Crispe, I.N.
(1991)
Phenotypic heterogeneity of intraepithelial T lymphocytes from mouse small intestine.
Immunology, 72(4),
pp. 555-562.
(PMID:2037315)
(PMCID:PMC1384377)
Book Sections
Kole, Abhisake and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Control of intestinal inflammation by interleukin-10.
In: Fillatreau, Simon and O'Garra, Anne (eds.)
Interleukin-10 in Health and Disease.
Series: Current topics in microbiology and immunology (380).
Springer: Heidelberg, pp. 19-38.
ISBN 9783662434918
(doi: 10.1007/978-3-662-43492-5_2)
Song-Zhao, George X. and Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2014)
Experimental mouse models of T cell-dependent inflammatory bowel disease.
In: Waisman, Ari and Becher, Burkhard (eds.)
T-Helper Cells: Methods and Protocols.
Series: Methods in molecular biology (1193).
Humana Press: New York, NY, pp. 199-211.
ISBN 9781493912117
(doi: 10.1007/978-1-4939-1212-4_18)
Maloy, Kevin J. ORCID: https://orcid.org/0000-0001-5795-7688
(2007)
Induction and regulation of inflammatory bowel disease in immunodeficient mice by distinct CD4+ T-cell subsets.
In: Fairchild, Paul J. (ed.)
Immunological Tolerance: Methods and Protocols.
Series: Methods in molecular biology (380).
Humana Press: Totowa, N.J., pp. 327-335.
ISBN 9781588296528
(doi: 10.1007/978-1-59745-395-0_19)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Manipulating autophagy and related pathways to optimise intestinal Treg cell function and ameliorate intestinal inflammation
Medical Research Council
2023 - 2026
- Regulation of intestinal immune homeostasis by NOD-like receptors
Wellcome Trust
2020 - 2022