Dr Jennifer Ann Black
- Affiliate Researcher (School of Infection & Immunity)
                        email: 
                        Jennifer.Stortz@glasgow.ac.uk
                    
RI III, Sir Graeme Davies Building, 120 University Place, Glasgow, G12 8TA
Publications
2025
    
    Black, J.A., Poulton, B.C. ORCID: https://orcid.org/0000-0002-9831-5697, Gonzaga, B., Iskantar, A., Paape, D. 
ORCID: https://orcid.org/0000-0003-4355-8058, Tosi, L.R.O. and McCulloch, R. 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2025)
  
AUK3 is required for faithful nuclear segregation in the bloodstream form of Trypanosoma brucei.
    
    Molecular and Biochemical Parasitology, 261,
	 
      111664.
    
    (doi: 10.1016/j.molbiopara.2024.111664)
    (PMID:39746453) 
     
  
  
2024
    
    Reis-Cunha, João L., Pimenta-Carvalho, Samuel A., Almeida, Laila V., Coqueiro-Dos-Santos, Anderson, Marques, Catarina A. ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer A., Damasceno, Jeziel 
ORCID: https://orcid.org/0000-0003-2077-3214, McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X, Bartholomeu, Daniella C. and Jeffares, Daniel C.
  
(2024)
  
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites.
    
    Genome Research, 34(3),
	  pp. 441-453.
     
    
    (doi: 10.1101/gr.278550.123)
    (PMID:38604731) 
    (PMCID:PMC11067883) 
  
  
2023
    
    Black, Jennifer A., Klinger, Christen M., Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Dacks, Joel B., Mottram, Jeremy C. and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2023)
  
AAK1-like: a putative pseudokinase with potential roles in cargo uptake in bloodstream form Trypanosoma brucei parasites.
    
    Journal of Eukaryotic Microbiology, 70(6),
	 
      e12994.
    
    (doi: 10.1111/jeu.12994)
    (PMID:37548427) 
    (PMCID:PMC10952953) 
  
  
Black, Jennifer A., Reis-Cunha, João Luís, Cruz, Angela. K. and Tosi, Luiz. R.O. (2023) Life in plastic, it’s fantastic! How Leishmania exploit genome instability to shape gene expression. Frontiers in Cellular and Infection Microbiology, 13, 1102462. (doi: 10.3389/fcimb.2023.1102462) (PMID:36779182) (PMCID:PMC9910336)
2022
    
    Faria, Joana, Briggs, Emma M., Black, Jennifer A. and McCulloch, Richard ORCID: https://orcid.org/0000-0001-5739-976X
  
(2022)
  
Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome.
    
    Current Opinion in Microbiology, 70,
	 
      102209.
    
    (doi: 10.1016/j.mib.2022.102209)
    (PMID:36215868) 
     
  
  
2021
    
    Silva, Gabriel L.A. ORCID: https://orcid.org/0009-0001-3114-2314, Tosi, Luiz R.O., McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X and Black, Jennifer Ann
  
(2021)
  
Unpicking the roles of DNA damage protein kinases in trypanosomatids.
    
    Frontiers in Cell and Developmental Biology, 9,
	 
      636615.
    
    (doi: 10.3389/fcell.2021.636615)
    (PMID:34422791) 
    (PMCID:PMC8377203) 
  
  
    
    Damasceno, Jeziel D. ORCID: https://orcid.org/0000-0003-2077-3214, Marques, Catarina A. 
ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer, Briggs, Emma and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2021)
  
Read, write, adapt: challenges and opportunities during kinetoplastid genome replication.
    
    Trends in Genetics, 37(1),
	  pp. 21-34.
     
    
    (doi: 10.1016/j.tig.2020.09.002)
    (PMID:32993968) 
    (PMCID:PMC9213392) 
  
  
2020
    
    Briggs, Emma M., Marques, Catarina ORCID: https://orcid.org/0000-0003-1324-5448, Reis-Cunha, Joao, Black, Jennifer, Campbell, Samantha, Damasceno, Jeziel 
ORCID: https://orcid.org/0000-0003-2077-3214, Bartholomeu, Daniella, Crouch, Kathryn 
ORCID: https://orcid.org/0000-0001-9310-4762 and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2020)
  
Next-generation analysis of trypanosomatid genome stability and instability.
    
    
      In: Michels, Paul A.M., Ginger, Michael L. and Zilberstein, Dan (eds.)
      Trypanosomatids: Methods and Protocols.
    
    
      Series: Methods in Molecular Biology (2116).
    
    Springer, pp. 225-262.
         ISBN 9781071602935
        (doi: 10.1007/978-1-0716-0294-2_15)
  
  
    
    Black, Jennifer Ann, Crouch, Kathryn ORCID: https://orcid.org/0000-0001-9310-4762, Lemgruber, Leandro 
ORCID: https://orcid.org/0000-0003-2832-6806, Lapsley, Craig, Dickens, Nicholas 
ORCID: https://orcid.org/0000-0003-0492-5855, Tosi, Luiz R.O., Mottram, Jeremy C. 
ORCID: https://orcid.org/0000-0001-5574-3766 and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2020)
  
Trypanosoma brucei ATR links DNA damage signalling during antigenic variation with regulation of RNA Polymerase I-transcribed surface antigens.
    
    Cell Reports, 30(3),
	  836-851.e5.
     
    
    (doi: 10.1016/j.celrep.2019.12.049)
    (PMID:31968257) 
    (PMCID:PMC6988115) 
  
  
2019
    
    Nnadi, Charles, Ebiloma, Godwin U., Black, Jennifer A., Nwodo, Ngozi, Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Schmidt, Thomas J. and De Koning, Harry P. 
ORCID: https://orcid.org/0000-0002-9963-1827
  
(2019)
  
Potent antitrypanosomal activities of 3-aminosteroids against African trypanosomes: investigation of cellular effects and of cross-resistance with existing drugs.
    
    Molecules, 24(2),
	 
      268.
    
    (doi: 10.3390/molecules24020268)
    (PMID:30642032) 
     
  
  
2017
Stortz, J. A. et al. (2017) Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei. PLoS Pathogens, 13(7), e1006477. (doi: 10.1371/journal.ppat.1006477) (PMID:28742144) (PMCID:PMC5542689)
Articles
    
    Black, J.A., Poulton, B.C. ORCID: https://orcid.org/0000-0002-9831-5697, Gonzaga, B., Iskantar, A., Paape, D. 
ORCID: https://orcid.org/0000-0003-4355-8058, Tosi, L.R.O. and McCulloch, R. 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2025)
  
AUK3 is required for faithful nuclear segregation in the bloodstream form of Trypanosoma brucei.
    
    Molecular and Biochemical Parasitology, 261,
	 
      111664.
    
    (doi: 10.1016/j.molbiopara.2024.111664)
    (PMID:39746453) 
     
  
  
    
    Reis-Cunha, João L., Pimenta-Carvalho, Samuel A., Almeida, Laila V., Coqueiro-Dos-Santos, Anderson, Marques, Catarina A. ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer A., Damasceno, Jeziel 
ORCID: https://orcid.org/0000-0003-2077-3214, McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X, Bartholomeu, Daniella C. and Jeffares, Daniel C.
  
(2024)
  
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites.
    
    Genome Research, 34(3),
	  pp. 441-453.
     
    
    (doi: 10.1101/gr.278550.123)
    (PMID:38604731) 
    (PMCID:PMC11067883) 
  
  
    
    Black, Jennifer A., Klinger, Christen M., Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Dacks, Joel B., Mottram, Jeremy C. and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2023)
  
AAK1-like: a putative pseudokinase with potential roles in cargo uptake in bloodstream form Trypanosoma brucei parasites.
    
    Journal of Eukaryotic Microbiology, 70(6),
	 
      e12994.
    
    (doi: 10.1111/jeu.12994)
    (PMID:37548427) 
    (PMCID:PMC10952953) 
  
  
Black, Jennifer A., Reis-Cunha, João Luís, Cruz, Angela. K. and Tosi, Luiz. R.O. (2023) Life in plastic, it’s fantastic! How Leishmania exploit genome instability to shape gene expression. Frontiers in Cellular and Infection Microbiology, 13, 1102462. (doi: 10.3389/fcimb.2023.1102462) (PMID:36779182) (PMCID:PMC9910336)
    
    Faria, Joana, Briggs, Emma M., Black, Jennifer A. and McCulloch, Richard ORCID: https://orcid.org/0000-0001-5739-976X
  
(2022)
  
Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome.
    
    Current Opinion in Microbiology, 70,
	 
      102209.
    
    (doi: 10.1016/j.mib.2022.102209)
    (PMID:36215868) 
     
  
  
    
    Silva, Gabriel L.A. ORCID: https://orcid.org/0009-0001-3114-2314, Tosi, Luiz R.O., McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X and Black, Jennifer Ann
  
(2021)
  
Unpicking the roles of DNA damage protein kinases in trypanosomatids.
    
    Frontiers in Cell and Developmental Biology, 9,
	 
      636615.
    
    (doi: 10.3389/fcell.2021.636615)
    (PMID:34422791) 
    (PMCID:PMC8377203) 
  
  
    
    Damasceno, Jeziel D. ORCID: https://orcid.org/0000-0003-2077-3214, Marques, Catarina A. 
ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer, Briggs, Emma and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2021)
  
Read, write, adapt: challenges and opportunities during kinetoplastid genome replication.
    
    Trends in Genetics, 37(1),
	  pp. 21-34.
     
    
    (doi: 10.1016/j.tig.2020.09.002)
    (PMID:32993968) 
    (PMCID:PMC9213392) 
  
  
    
    Black, Jennifer Ann, Crouch, Kathryn ORCID: https://orcid.org/0000-0001-9310-4762, Lemgruber, Leandro 
ORCID: https://orcid.org/0000-0003-2832-6806, Lapsley, Craig, Dickens, Nicholas 
ORCID: https://orcid.org/0000-0003-0492-5855, Tosi, Luiz R.O., Mottram, Jeremy C. 
ORCID: https://orcid.org/0000-0001-5574-3766 and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2020)
  
Trypanosoma brucei ATR links DNA damage signalling during antigenic variation with regulation of RNA Polymerase I-transcribed surface antigens.
    
    Cell Reports, 30(3),
	  836-851.e5.
     
    
    (doi: 10.1016/j.celrep.2019.12.049)
    (PMID:31968257) 
    (PMCID:PMC6988115) 
  
  
    
    Nnadi, Charles, Ebiloma, Godwin U., Black, Jennifer A., Nwodo, Ngozi, Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Schmidt, Thomas J. and De Koning, Harry P. 
ORCID: https://orcid.org/0000-0002-9963-1827
  
(2019)
  
Potent antitrypanosomal activities of 3-aminosteroids against African trypanosomes: investigation of cellular effects and of cross-resistance with existing drugs.
    
    Molecules, 24(2),
	 
      268.
    
    (doi: 10.3390/molecules24020268)
    (PMID:30642032) 
     
  
  
Stortz, J. A. et al. (2017) Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei. PLoS Pathogens, 13(7), e1006477. (doi: 10.1371/journal.ppat.1006477) (PMID:28742144) (PMCID:PMC5542689)
Book Sections
    
    Briggs, Emma M., Marques, Catarina ORCID: https://orcid.org/0000-0003-1324-5448, Reis-Cunha, Joao, Black, Jennifer, Campbell, Samantha, Damasceno, Jeziel 
ORCID: https://orcid.org/0000-0003-2077-3214, Bartholomeu, Daniella, Crouch, Kathryn 
ORCID: https://orcid.org/0000-0001-9310-4762 and McCulloch, Richard 
ORCID: https://orcid.org/0000-0001-5739-976X
  
(2020)
  
Next-generation analysis of trypanosomatid genome stability and instability.
    
    
      In: Michels, Paul A.M., Ginger, Michael L. and Zilberstein, Dan (eds.)
      Trypanosomatids: Methods and Protocols.
    
    
      Series: Methods in Molecular Biology (2116).
    
    Springer, pp. 225-262.
         ISBN 9781071602935
        (doi: 10.1007/978-1-0716-0294-2_15)