Basic, applied, clinical and translational research

Professor Gerry Graham analysing a petri dish in the lab

Our Institute is divided into four main research areas:

Immunology and Inflammation

  • Cytokine and chemokine biology
  • Immune cell signalling
  • Advanced imaging and flow cytometry
  • T cell, dendritic cell and macrophage biology
  • Immunological tolerance and memory
  • Bioinformatics of immune responses and infection
  • Translation currently focused in rheumatology, dermatology, respiratory and nervous system diseases


  • Mechanisms of disease in human and veterinary pathogens
  • Mechanisms of microbial evolution and the emergence of new pathogens• Structural and functional analysis of bacterial virulence factors
  • Addressing AMR – Alternative strategies for treating infection
  • Development of in vitro and in vivo models of bacterial disease


  • Global analyses of parasite biology, including genomics, metabolomics and ecological approaches
  • Drug resistance, immune evasion, invasiveness, Differentiation
  • Pathogenesis
  • Research links with disease-endemic countries, particularly in Africa


  • Molecular virology to in vivo pathogenesis
  • Virus-cell interactions, viral immunology, viral ecology and emergence
  • Structural virology
  • Clinical and veterinary virology, viral diagnostics, virus epidemiology, mathematical modelling and bioinformatics