Dr Christopher Loughrey

  • Reader (Institute of Cardiovascular & Medical Sciences)
  • MVLS College International Dean (MVLS College Senior Management)
  • Associate (School of Veterinary Medicine)

Biography

Dr. Christopher Loughrey is a Principal Investigator at the Glasgow Cardiovascular Research Centre, University of Glasgow, UK. He graduated in Veterinary Medicine and Surgery with commendation in 2000 and subsequently completed a PhD in 2003 on how different FK-506 binding proteins alter cardiomyocyte calcium handling. Following this, he held a post-doctoral position at the University of Glasgow during which time he led a collaboration with a pharmaceutical company to discover the cardiac-related action of novel therapeutic drugs including K201/JTV519. In 2005, Dr. Loughrey established his own laboratory and was appointed as a Lecturer, then Senior Lecturer (2010) and is currently a Reader (2017). He has been a Principal Investigator on a number of project grants funded by the Medical Research Council, British Heart Foundation, Heart Research UK, Medical Research Scotland and Chief Scientist Office. He is currently the Executive Deputy Editor of Cardiovascular Research and serves on the Editorial board of the British Journal of Pharmacology and Frontiers in Physiology; Cardiac Electrophysiology.


Research interests

Member: Cardiac Research 

 

 

 

Dr. Loughrey’s laboratory use an integrative approach to study the pathophysiology of heart disease. His group has a particular focus on the mechanisms contributing to changes in heart architecture and function following myocardial infarction and how this adverse cardiac remodelling leads to heart failure. His group have identified several new therapeutic targets with translational potential for limiting the progression to heart failure in patients with myocardial infarction.

 

Key research areas include: Excitation-contraction coupling in ventricular cardiomyocytes, sarcoplasmic reticulum–mediated calcium handling, adverse cardiac remodelling, myocardial infarction, heart failure, ischaemia-reperfusion injury, runt-related transcription factors (Runx1, Runx2 and Runx3) and cathepsins.

 

Dr. Loughrey’s laboratory has expertise in a number of methodologies which span the level of the single cell, isolated organ, whole animal in vivo and patient including: confocal microscopy, single cell electrophysiology, fluorescence measurements/imaging, Western blotting, rtqPCR, isolated heart techniques (Langendorff perfusion and working heart preparations) and in vivo cardiac phenotyping/micro-surgery (e.g. intra-ventricular pressure-volume measurements, electrocardiography, echocardiography and mouse models of myocardial infarction and ischaemia–reperfusion injury)


Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Elucidation of molecular pathways underlying cardiac disease caused by Col4a1 mutations
    Heart Research UK
    2018 - 2021
     
  • Investigating the Therapeutic Potential of Runx1 for Myocardial Infarction
    British Heart Foundation
    2018 - 2021
     
  • Small molecules activating Nrf2 as a therapeutic approach to prevent cardiac ischemiareperfusion
    British Heart Foundation
    2018 - 2019
     
  • Cardiac gene therapy with angiotensin-(1-9): dissecting the underlying mechanism for preservation of cardiac function post-myocardial infarction
    British Heart Foundation
    2017 - 2020
     
  • Small molecules activating Nrf2 as a therapeutic approach to prevent cardiac ischemia-reperfusion injury
    British Heart Foundation
    2017 - 2019
     
  • INSPIRE Award
    Academy of Medical Sciences
    2016 - 2017
     
  • INVESTIGATING THE ROLE OF RUNX1 IN THE HEART POST-MYOCARDIAL INFARCTION
    Medical Research Council
    2015 - 2018
     
  • Investigation of Osteopontin as a candidate gene for left ventricular hypertrophy
    British Heart Foundation
    2014 - 2018
     
  • Angiotensin-(1-9) a novel peptide therapeutic for improving cardiac function.
    Medical Research Council
    2014 - 2015
     
  • Investigating the therapeutic potential of cathepsin-L inhibition to limit ischaemia-reperfusion injury in the heart
    Chief Scientist Office
    2013 - 2016
     
  • Investigating the potential of cathepsin-L as a common therapeutic target and biomarker for coronary heart disease and African trypanosomiasis (ISSF Catalyst Fund)
    Wellcome Trust
    2011 - 2014
     
  • Angiotensin 1-9 and angiotensin 1-7: assessment of their mechanisms of action as counter-regulatory renin angiotensin system peptides in cardiovascular disease
    British Heart Foundation
    2011 - 2015
     
  • Investigating the expression and function of RUNX1 in cardiac tissue during myocardial infarction
    British Heart Foundation
    2009 - 2011
     
  • The role of direct parasite-cardiomyocyte interaction in the pathogenesis of the cardiac dysfunction observed in mammals with African trypanosomiasis
    Royal College of Veterinary Surgeons
    2008 - 2009
     
  • Targeted disruption of sarcoplasmic reticulum mediated Ca2+ handling and diastolic dysfunction: A comaprison between isolated cardiomyocytes and the whole heart.
    Heart Research UK
    2007 - 2009
     
  • Investigating the role of intracellular calcium in the left ventricular diastolic dysfunction
    Medical Research Scotland
    2006 - 2008
     
  • Cellular Basis of Arrhythmias:The Inter-Relationship between Ca2+ Transients and Ca2+ Waves in Cardiac Muscle
    British Heart Foundation
    2006 - 2009
     
  • Use of Micro-Conductance Technology to investigate the link between altered sarcoplasmic reticulum calcium dynamics & diastolic dysfunction.
    Tenovus Scotland
    2005 - 2006
     
  • Use of micro-conductance technology to study cardiac pressure-volume (PV) relations in ex vivo whole rabbit hearts during acute application.
    The Royal Society
    2005 - 2006
     

Teaching

Dr. Loughrey is the Module Leader for cardiovascular teaching at the School of Veterinary Medicine and has supervised a substantial number of MRes and PhD students to completion since 2005.

He also teaches, assesses and mentors both undergraduates and postgraduates on the following degree programmes:

  • School of Veterinary Medical: (BVMS and BSc Veterinary Biosciences

  • School of Life Sciences: (BSc Hons Level 4, MRes Biomedicine, MRes Integrative Mammalian Biology)

  • Institute of Cardiovascular & Medical Sciences (BHF 4 MRes programme)

I am the Module Leader for cardiovascular teaching at the School of Veterinary Medicine and have supervised a significant number of MRes and PhD students to completion since 2005.
I also teach, assess and mentor both undergraduates and postgraduates on the following degree programmes;
School of Veterinary Medical: (BVMS and BSc Veterinary Biosciences)
School of Life Sciences: (BSc Hons Level 4, MRes Biomedicine, MRes Integrative Mammalian Biology)
Institute of Cardiovascular & Medical Sciences (BHF 4 MRes programme)


Additional information

Editorial Board

  • 2018 - present: Executive Deputy Editor: Cardiovascular Research
  • 2016 - present: Editor: British Journal of Pharmacology
  • 2016 - present: Editor: Frontiers in Physiology; Cardiac Electrophysiology

Grant Advisory Board

  • 2013: Member of the Clinical Veterinary Research Training Wellcome Trust grant panel.
  • 2010: Wellcome Trust - International Mouse Phenotyping Project Advisory Meeting

Invited International Presentations

  • 2009: Aetas Pharma Ltd - Meeting
  • 2008: USA - Gordon Research Conference - Co-chair of conference symposium
  • 2008: Trondheim, Norway - Conference at Trondheim University
  • 2007: Aetas Pharma Ltd - Meeting
  • 2003: British Cardiac Society (UK) - Conference

Prizes, Awards and Distinctions

  • 2008: Fellow of the Higher Education Academy
  • 2005: 'Annual Presentations by Britain's Top Young Scientists'
  • 2003: British Cardiac Society - Judge's Prize for Oral Presentation
  • 2001: Association of Veterinary Teachers and Research Workers (AVTRW) - President's Prize for Oral Presentation
  • 2000: BVMS with commendation
  • 1997: Silver Medal by the Royal Agricultural Society - BVMS Degree
  • 1997: Eukanuba Nutrition Prize - BVMS Degree

Professional Learned Society

  • 2017 - present: American Heart Association – Professional Member (Basic Cardiovascular Sciences)
  • 2005 - present: European Society of Cardiology (Cardiac Cellular Electrophysiology) - Member
  • 2005 - present: Veterinary Cardiology Society - Member
  • 2002 - 2016: Biophysical Society - USA - Member
  • 2002 - present: British Cardiac Society - Member
  • 2002 - present: International Society for Heart Research - Member
  • 2001 - present: Physiological Society - Member
  • 2000 - present: British Veterinary Association - Member
  • 2000 - present: Royal College of Veterinary Surgeons - Member

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002
Number of items: 26.

2018

Guzik, T. J. et al. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114(12), pp. 1565-1568. (doi:10.1093/cvr/cvy214)

2017

McCarroll, C. S. et al. (2017) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137(1), pp. 57-70. (doi:10.1161/CIRCULATIONAHA.117.028911) (PMID:29030345) (PMCID:PMC5757664)

2016

Fattah, C. et al. (2016) Gene therapy with Angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction. Journal of the American College of Cardiology, 68(24), pp. 2652-2666. (doi:10.1016/j.jacc.2016.09.946) (PMID:27978950) (PMCID:PMC5158000)

Ross, P. D. et al. (2016) Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics, 25(20), pp. 4389-4404. (doi:10.1093/hmg/ddw269) (PMID:28173151)

2015

McCarroll, C. S., Rossor, C. L., Morrison, L. R., Morrison, L. J. and Loughrey, C. M. (2015) A pre-clinical animal model of Trypanosoma brucei infection demonstrating cardiac dysfunction. PLoS Neglected Tropical Diseases, 9(5), e0003811. (doi:10.1371/journal.pntd.0003811) (PMID:26023927) (PMCID:PMC4449042)

2014

McKinney, C. A., Fattah, C., Loughrey, C. M. , Milligan, G. and Nicklin, S. A. (2014) Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling. Clinical Science, 126, pp. 815-827. (doi:10.1042/CS20130436)

2013

Elliott, E.B. et al. (2013) T. brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes. Cardiovascular Research, 100(2), pp. 325-335. (doi:10.1093/cvr/cvt187) (PMID:23892734) (PMCID:PMC3797627)

Loughrey, C.M. and Gray, G.A. (2013) Advancing our understanding of the pathophysiology of cardiac disease using in vivo assessment of heart structure and function in rodent models. Experimental Physiology, 98(3), pp. 599-600. (doi:10.1113/expphysiol.2012.064550)

2012

Elliott, E.B., Kelly, A., Smith, G.L. and Loughrey, C.M. (2012) Isolated rabbit working heart function during progressive inhibition of myocardial SERCA activity. Circulation Research, 110(12), pp. 1618-1627. (doi:10.1161/CIRCRESAHA.111.262337)

Kelly, A., Elliott, E.B., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2012) The effect of K201 on isolated working rabbit heart mechanical function during pharmacologically-induced Ca2+ overload. British Journal of Pharmacology, 165(4b), pp. 1068-1083. (doi:10.1111/j.1476-5381.2011.01531.x)

2011

Currie, S., Elliott, E.B., Smith, G.L. and Loughrey, C.M. (2011) Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention—An in vivo perspective. Pharmacology and Therapeutics, 131(2), pp. 204-220. (doi:10.1016/j.pharmthera.2011.02.006)

Elliott, E.B., Hasumi, H., Otani, N., Matsuda, T., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2011) K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca2+ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes. Basic Research in Cardiology, 106(6), pp. 1009-1022. (doi:10.1007/s00395-011-0218-4)

2010

Toischer, K. et al. (2010) K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum. Basic Research in Cardiology, 105(2), pp. 279-287. (doi:10.1007/s00395-009-0057-8)

2007

Volkers, M. et al. (2007) S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium, 41(2), pp. 135-143. (doi:10.1016/j.ceca.2006.06.001) (PMID:16919727)

Loughrey, C. , Otani, N., Seidler, T., Craig, M., Matsuda, R., Kaneko, N. and Smith, G. (2007) K201 modulates excitation-contraction coupling and spontaneous Ca2+ release in normal adult rabbit ventricular cardiomyocytes. Cardiovascular Research, 76(2), pp. 236-246. (doi:10.1016/j.cardiores.2007.06.014)

Seidler, T., Loughrey, C. , Zibrova, D., Kettlewell, S., Teucher, N., Kogler, H., Hasenfuss, G. and Smith, G. (2007) Overexpression of FK-506-binding protein 12.0 modulates excitation-contraction coupling in adult rabbit ventricular cardiomyocytes. Circulation Research, 101(10), pp. 1020-1029. (doi:10.1161/CIRCRESAHA.107.154609)

2006

Colotti, G., Zamparelli, C., Verzili, D., Mella, M., Loughrey, C. , Smith, G. and Chiancone, E. (2006) The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca2+-dependent interaction with annexin VII and the cardiac ryanodine receptor. Biochemistry, 45(41), pp. 12519-12529. (doi:10.1021/bi060416a)

2005

Miller, S., Currie, S., Loughrey, C. , Kettlewell, S., Seidler, T., Reynolds, D., Hasenfuss, G. and Smith, G. (2005) Effects of calsequestrin over-expression on excitation-contraction coupling in isolated rabbit cardiomyocytes. Cardiovascular Research, 67(4), pp. 667-677. (doi:10.1016/j.cardiores.2005.04.023)

2004

Loughrey, C.M. , Seidler, T., Miller, S.L.W., Prestle, J., MacEachern, K.E., Reynolds, D.F., Hasenfuss, G. and Smith, G.L. (2004) Over-expression of FK506-binding protein FKBP12.6 alters excitation-contraction coupling in adult rabbit cardiomyocytes. Journal of Physiology, 556(3), pp. 919-934. (doi:10.1113/jphysiol.2003.057166)

Loughrey, C.M. , Smith, G.L. and MacEachern, K.E. (2004) Comparison of Ca2+ release and uptake characteristics of the sarcoplasmic reticulum in isolated horse and rabbit cardiomyocytes. American Journal of Physiology: Heart and Circulatory Physiology, 287(3), H1149-H1159. (doi:10.1152/ajpheart.00060.2004)

Currie, S., Loughrey, C. , Craig, M. and Smith, G. (2004) Calcium/calmodulin-dependent protein kinase II delta associates with the ryanodine receptor complex and regulates channel function in rabbit heart. Biochemical Journal, 377(2), pp. 357-366. (doi:10.1042/BJ200310431)

Wokosin, D., Loughrey, C. and Smith, G. (2004) Characterization of a range of fura dyes with two-photon excitation. Biophysical Journal, 86(3), pp. 1726-1738. (doi:10.1016/S0006-3495(04)74241-1)

2003

Loughrey, C.M. , MacEachern, K.E., Cooper, J. and Smith, G.L. (2003) Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics. Cell Calcium, 34(1), pp. 1-9. (doi:10.1016/S0143-4160(03)00012-5)

Seidler, T. et al. (2003) Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes. Circulation Research, 93(2), pp. 132-139. (doi:10.1161/01.RES.0000081596.90205.E2)

Zhang, H. et al. (2003) Dynamics of cardiac intracellular Ca2+ handling - from experiments to virtual cells. International Journal of Bifurcation and Chaos, 13(12), pp. 3535-3560. (doi:10.1142/S0218127403008843)

2002

Loughrey, C.M. , MacEachern, K.E., Neary, P. and Smith, G.L. (2002) The relationship between intracellular [Ca2+] and Ca2+ wave characteristics in permeabilised cardiomyocytes from the rabbit. Journal of Physiology, 543(3), pp. 859-870. (doi:10.1113/jphysiol.2002.021519)

This list was generated on Sun Apr 21 22:35:13 2019 BST.
Jump to: Articles
Number of items: 26.

Articles

Guzik, T. J. et al. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114(12), pp. 1565-1568. (doi:10.1093/cvr/cvy214)

McCarroll, C. S. et al. (2017) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137(1), pp. 57-70. (doi:10.1161/CIRCULATIONAHA.117.028911) (PMID:29030345) (PMCID:PMC5757664)

Fattah, C. et al. (2016) Gene therapy with Angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction. Journal of the American College of Cardiology, 68(24), pp. 2652-2666. (doi:10.1016/j.jacc.2016.09.946) (PMID:27978950) (PMCID:PMC5158000)

Ross, P. D. et al. (2016) Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics, 25(20), pp. 4389-4404. (doi:10.1093/hmg/ddw269) (PMID:28173151)

McCarroll, C. S., Rossor, C. L., Morrison, L. R., Morrison, L. J. and Loughrey, C. M. (2015) A pre-clinical animal model of Trypanosoma brucei infection demonstrating cardiac dysfunction. PLoS Neglected Tropical Diseases, 9(5), e0003811. (doi:10.1371/journal.pntd.0003811) (PMID:26023927) (PMCID:PMC4449042)

McKinney, C. A., Fattah, C., Loughrey, C. M. , Milligan, G. and Nicklin, S. A. (2014) Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling. Clinical Science, 126, pp. 815-827. (doi:10.1042/CS20130436)

Elliott, E.B. et al. (2013) T. brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes. Cardiovascular Research, 100(2), pp. 325-335. (doi:10.1093/cvr/cvt187) (PMID:23892734) (PMCID:PMC3797627)

Loughrey, C.M. and Gray, G.A. (2013) Advancing our understanding of the pathophysiology of cardiac disease using in vivo assessment of heart structure and function in rodent models. Experimental Physiology, 98(3), pp. 599-600. (doi:10.1113/expphysiol.2012.064550)

Elliott, E.B., Kelly, A., Smith, G.L. and Loughrey, C.M. (2012) Isolated rabbit working heart function during progressive inhibition of myocardial SERCA activity. Circulation Research, 110(12), pp. 1618-1627. (doi:10.1161/CIRCRESAHA.111.262337)

Kelly, A., Elliott, E.B., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2012) The effect of K201 on isolated working rabbit heart mechanical function during pharmacologically-induced Ca2+ overload. British Journal of Pharmacology, 165(4b), pp. 1068-1083. (doi:10.1111/j.1476-5381.2011.01531.x)

Currie, S., Elliott, E.B., Smith, G.L. and Loughrey, C.M. (2011) Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention—An in vivo perspective. Pharmacology and Therapeutics, 131(2), pp. 204-220. (doi:10.1016/j.pharmthera.2011.02.006)

Elliott, E.B., Hasumi, H., Otani, N., Matsuda, T., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2011) K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca2+ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes. Basic Research in Cardiology, 106(6), pp. 1009-1022. (doi:10.1007/s00395-011-0218-4)

Toischer, K. et al. (2010) K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum. Basic Research in Cardiology, 105(2), pp. 279-287. (doi:10.1007/s00395-009-0057-8)

Volkers, M. et al. (2007) S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium, 41(2), pp. 135-143. (doi:10.1016/j.ceca.2006.06.001) (PMID:16919727)

Loughrey, C. , Otani, N., Seidler, T., Craig, M., Matsuda, R., Kaneko, N. and Smith, G. (2007) K201 modulates excitation-contraction coupling and spontaneous Ca2+ release in normal adult rabbit ventricular cardiomyocytes. Cardiovascular Research, 76(2), pp. 236-246. (doi:10.1016/j.cardiores.2007.06.014)

Seidler, T., Loughrey, C. , Zibrova, D., Kettlewell, S., Teucher, N., Kogler, H., Hasenfuss, G. and Smith, G. (2007) Overexpression of FK-506-binding protein 12.0 modulates excitation-contraction coupling in adult rabbit ventricular cardiomyocytes. Circulation Research, 101(10), pp. 1020-1029. (doi:10.1161/CIRCRESAHA.107.154609)

Colotti, G., Zamparelli, C., Verzili, D., Mella, M., Loughrey, C. , Smith, G. and Chiancone, E. (2006) The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca2+-dependent interaction with annexin VII and the cardiac ryanodine receptor. Biochemistry, 45(41), pp. 12519-12529. (doi:10.1021/bi060416a)

Miller, S., Currie, S., Loughrey, C. , Kettlewell, S., Seidler, T., Reynolds, D., Hasenfuss, G. and Smith, G. (2005) Effects of calsequestrin over-expression on excitation-contraction coupling in isolated rabbit cardiomyocytes. Cardiovascular Research, 67(4), pp. 667-677. (doi:10.1016/j.cardiores.2005.04.023)

Loughrey, C.M. , Seidler, T., Miller, S.L.W., Prestle, J., MacEachern, K.E., Reynolds, D.F., Hasenfuss, G. and Smith, G.L. (2004) Over-expression of FK506-binding protein FKBP12.6 alters excitation-contraction coupling in adult rabbit cardiomyocytes. Journal of Physiology, 556(3), pp. 919-934. (doi:10.1113/jphysiol.2003.057166)

Loughrey, C.M. , Smith, G.L. and MacEachern, K.E. (2004) Comparison of Ca2+ release and uptake characteristics of the sarcoplasmic reticulum in isolated horse and rabbit cardiomyocytes. American Journal of Physiology: Heart and Circulatory Physiology, 287(3), H1149-H1159. (doi:10.1152/ajpheart.00060.2004)

Currie, S., Loughrey, C. , Craig, M. and Smith, G. (2004) Calcium/calmodulin-dependent protein kinase II delta associates with the ryanodine receptor complex and regulates channel function in rabbit heart. Biochemical Journal, 377(2), pp. 357-366. (doi:10.1042/BJ200310431)

Wokosin, D., Loughrey, C. and Smith, G. (2004) Characterization of a range of fura dyes with two-photon excitation. Biophysical Journal, 86(3), pp. 1726-1738. (doi:10.1016/S0006-3495(04)74241-1)

Loughrey, C.M. , MacEachern, K.E., Cooper, J. and Smith, G.L. (2003) Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics. Cell Calcium, 34(1), pp. 1-9. (doi:10.1016/S0143-4160(03)00012-5)

Seidler, T. et al. (2003) Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes. Circulation Research, 93(2), pp. 132-139. (doi:10.1161/01.RES.0000081596.90205.E2)

Zhang, H. et al. (2003) Dynamics of cardiac intracellular Ca2+ handling - from experiments to virtual cells. International Journal of Bifurcation and Chaos, 13(12), pp. 3535-3560. (doi:10.1142/S0218127403008843)

Loughrey, C.M. , MacEachern, K.E., Neary, P. and Smith, G.L. (2002) The relationship between intracellular [Ca2+] and Ca2+ wave characteristics in permeabilised cardiomyocytes from the rabbit. Journal of Physiology, 543(3), pp. 859-870. (doi:10.1113/jphysiol.2002.021519)

This list was generated on Sun Apr 21 22:35:13 2019 BST.