Miss Stacey Hoare
- Chief Technician/Laboratory Manager (Cancer Sciences Professional Services)
telephone:
01413308707
email:
Stacey.Hoare@glasgow.ac.uk
School of Cancer Sciences, Wolfson Wohl Cancer Research Cen, Garscube Estate, Glasgow G61 1QH
Publications
2014
Bilsland, Alan E. ORCID: https://orcid.org/0000-0003-0957-3908, Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J., Roffey, Jon and Keith, W. Nicol
ORCID: https://orcid.org/0000-0001-7862-3580
(2014)
Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms.
PLoS Computational Biology, 10(2),
e1003448.
(doi: 10.1371/journal.pcbi.1003448)
(PMID:24550717)
(PMCID:PMC3923661)
2012
Venturini, L., Daidone, M.G., Motta, R., Cimino-Reale, G., Hoare, S.F., Gronchi, A., Folini, M., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Zaffaroni, N.
(2012)
Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance.
Neuro-Oncology, 14(6),
pp. 736-744.
(doi: 10.1093/neuonc/nos083)
2011
Soo, J.K. et al. (2011) Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression. Pigment Cell and Melanoma Research, 24(3), pp. 490-503. (doi: 10.1111/j.1755-148X.2011.00850.x)
2010
Lafferty-Whyte, K., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Hoare, S.F., Burns, S., Zaffaroni, N., Cairney, C.J. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2010)
TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression.
Neoplasia, 12(5),
pp. 405-414.
2009
Bilsland, A.E., Hoare, S.F., Stevenson, K.H., Plumb, J.A., Gomez-Roman, N. ORCID: https://orcid.org/0000-0002-2325-7517, Cairney, C.J., Burns, S., Lafferty-Whyte, K., Hammonds, T. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2009)
Dynamic telomerase gene suppression via network effects of GSK3 inhibition.
PLoS ONE, 4(7),
e6459.
(doi: 10.1371/journal.pone.0006459)
(PMID:19649288)
(PMCID:PMC2714081)
Zhang, X. et al. (2009) A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. Journal of Cell Biology, 184(1), pp. 67-82. (doi: 10.1083/jcb.200801009)
2008
Cairney, CJ, Hoare, SF, Daidone, MG, Zaffaroni, N and Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580
(2008)
High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma.
British Journal of Cancer, 98(8),
pp. 1467-1474.
(doi: 10.1038/sj.bjc.6604328)
Saretzki, G. et al. (2008) Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells. Stem Cells, 26(2), pp. 455-464. (doi: 10.1634/stemcells.2007-0628)
2006
Anderson, C.J., Hoare, S.F., Ashcroft, M., Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908 and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2006)
Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms.
Oncogene, 25(1),
pp. 61-69.
(doi: 10.1038/sj.onc.1209011)
Serakinci, N., Hoare, S.F., Kassem, M., Atkinson, S.P. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2006)
Telomerase promoter reprogramming and interaction with general transcription factors in the human mesenchymal stem cell.
Regenerative Medicine, 1(1),
pp. 125-131.
(doi: 10.2217/17460781.1.1.125)
2005
Atkinson, S.P., Hoare, S.F., Glasspool, R.M. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2005)
Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters.
Cancer Research, 65(17),
pp. 7585-7590.
(doi: 10.1158/0008-5472.CAN-05-1715)
Drummond, M.W., Hoare, S.F., Monaghan, A., Graham, S.M., Alcorn, M.J., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Holyoake, T.L.
(2005)
Dysregulated expression of the major telomerase components in leukaemic stem cells.
Leukemia, 19(3),
pp. 381-389.
(doi: 10.1038/sj.leu.2403616)
Glasspool, R.M., Burns, S., Hoare, S.F., Svensson, C. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2005)
The hTERT and hTERC telomerase gene promoters are activated by the second Exon of the adenoviral protein, E1A, identifying the transcriptional co-repressor CtBP as a potential repressor of both genes.
Neoplasia, 7(6),
pp. 614-622.
(doi: 10.1593/neo.04766)
2004
Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Hoare, S.F.
(2004)
Detection of telomerase hTERT gene expression and its splice variants by RT-PCR.
In: Roulston, J.E. and Bartlett, J.M.S. (eds.)
Molecular Diagnosis of Cancer: Methods and Protocols.
Series: Methods in molecular medicine (97).
Humana Press: Totowa, NJ, USA, pp. 297-309.
ISBN 9781588291608
2003
Madhusudan, S. et al. (2003) A multicentre phase II trial of bryostatin-1 in patients with advanced renal cancer. British Journal of Cancer, 89, pp. 1418-1422. (doi: 10.1038/sj.bjc.6601321)
Zhao, J.Q., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Hoare, S.F. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2003)
Involvement of NF-Y and Sp1 binding sequences in basal transcription of the human telomerase RNA gene.
FEBS Letters, 536(1-3),
pp. 111-119.
(doi: 10.1016/S0014-5793(03)00038-3)
2001
Hoare, S.F., Bryce, L.A., Wisman, G.B.A., Burns, S., Going, J.J., van der Zee, A.G.J. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2001)
Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter.
Cancer Research, 61(1),
pp. 27-32.
2000
Bryce, L.A., Morrison, N., Hoare, S.F., Muir, S. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2000)
Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization.
Neoplasia, 2(3),
pp. 197-201.
Zhao, J.Q., Glasspool, R.M., Hoare, S.F., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Szatmari, I. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2000)
Activation of telomerase RNA gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3.
Neoplasia, 2(6),
pp. 531-539.
1998
Zhao, J.Q., Hoare, S.F., McFarlane, R., Muir, S., Parkinson, E.K., Black, D.M. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1998)
Cloning and characterization of human and mouse telomerase RNA gene promoter sequences.
Oncogene, 16(10),
pp. 1345-1350.
1997
Hoare, S.F., Freeman, C.A., Coutts, J.C., Varley, J.M., James, L. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1997)
Identification of genetic changes associated with drug resistance by reverse in situ hybridization.
British Journal of Cancer, 75(2),
pp. 275-282.
Soder, A.I., Hoare, S.F., Muir, S., Going, J.J., Parkinson, E.K. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1997)
Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer.
Oncogene, 14(9),
pp. 1013-1021.
Soder, A.I., Hoare, S.F., Muire, S., Balmain, A., Parkinson, E.K. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1997)
Mapping of the gene for the mouse telomerase RNA component, Terc, to chromosome 3 by fluorescence in situ hybridization and mouse chromosome painting.
Genomics, 41(2),
pp. 293-294.
(doi: 10.1006/geno.1997.4621)
Articles
Bilsland, Alan E. ORCID: https://orcid.org/0000-0003-0957-3908, Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J., Roffey, Jon and Keith, W. Nicol
ORCID: https://orcid.org/0000-0001-7862-3580
(2014)
Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms.
PLoS Computational Biology, 10(2),
e1003448.
(doi: 10.1371/journal.pcbi.1003448)
(PMID:24550717)
(PMCID:PMC3923661)
Venturini, L., Daidone, M.G., Motta, R., Cimino-Reale, G., Hoare, S.F., Gronchi, A., Folini, M., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Zaffaroni, N.
(2012)
Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance.
Neuro-Oncology, 14(6),
pp. 736-744.
(doi: 10.1093/neuonc/nos083)
Soo, J.K. et al. (2011) Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression. Pigment Cell and Melanoma Research, 24(3), pp. 490-503. (doi: 10.1111/j.1755-148X.2011.00850.x)
Lafferty-Whyte, K., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Hoare, S.F., Burns, S., Zaffaroni, N., Cairney, C.J. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2010)
TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression.
Neoplasia, 12(5),
pp. 405-414.
Bilsland, A.E., Hoare, S.F., Stevenson, K.H., Plumb, J.A., Gomez-Roman, N. ORCID: https://orcid.org/0000-0002-2325-7517, Cairney, C.J., Burns, S., Lafferty-Whyte, K., Hammonds, T. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2009)
Dynamic telomerase gene suppression via network effects of GSK3 inhibition.
PLoS ONE, 4(7),
e6459.
(doi: 10.1371/journal.pone.0006459)
(PMID:19649288)
(PMCID:PMC2714081)
Zhang, X. et al. (2009) A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. Journal of Cell Biology, 184(1), pp. 67-82. (doi: 10.1083/jcb.200801009)
Cairney, CJ, Hoare, SF, Daidone, MG, Zaffaroni, N and Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580
(2008)
High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma.
British Journal of Cancer, 98(8),
pp. 1467-1474.
(doi: 10.1038/sj.bjc.6604328)
Saretzki, G. et al. (2008) Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells. Stem Cells, 26(2), pp. 455-464. (doi: 10.1634/stemcells.2007-0628)
Anderson, C.J., Hoare, S.F., Ashcroft, M., Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908 and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2006)
Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms.
Oncogene, 25(1),
pp. 61-69.
(doi: 10.1038/sj.onc.1209011)
Serakinci, N., Hoare, S.F., Kassem, M., Atkinson, S.P. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2006)
Telomerase promoter reprogramming and interaction with general transcription factors in the human mesenchymal stem cell.
Regenerative Medicine, 1(1),
pp. 125-131.
(doi: 10.2217/17460781.1.1.125)
Atkinson, S.P., Hoare, S.F., Glasspool, R.M. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2005)
Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters.
Cancer Research, 65(17),
pp. 7585-7590.
(doi: 10.1158/0008-5472.CAN-05-1715)
Drummond, M.W., Hoare, S.F., Monaghan, A., Graham, S.M., Alcorn, M.J., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Holyoake, T.L.
(2005)
Dysregulated expression of the major telomerase components in leukaemic stem cells.
Leukemia, 19(3),
pp. 381-389.
(doi: 10.1038/sj.leu.2403616)
Glasspool, R.M., Burns, S., Hoare, S.F., Svensson, C. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2005)
The hTERT and hTERC telomerase gene promoters are activated by the second Exon of the adenoviral protein, E1A, identifying the transcriptional co-repressor CtBP as a potential repressor of both genes.
Neoplasia, 7(6),
pp. 614-622.
(doi: 10.1593/neo.04766)
Madhusudan, S. et al. (2003) A multicentre phase II trial of bryostatin-1 in patients with advanced renal cancer. British Journal of Cancer, 89, pp. 1418-1422. (doi: 10.1038/sj.bjc.6601321)
Zhao, J.Q., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Hoare, S.F. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2003)
Involvement of NF-Y and Sp1 binding sequences in basal transcription of the human telomerase RNA gene.
FEBS Letters, 536(1-3),
pp. 111-119.
(doi: 10.1016/S0014-5793(03)00038-3)
Hoare, S.F., Bryce, L.A., Wisman, G.B.A., Burns, S., Going, J.J., van der Zee, A.G.J. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2001)
Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter.
Cancer Research, 61(1),
pp. 27-32.
Bryce, L.A., Morrison, N., Hoare, S.F., Muir, S. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(2000)
Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization.
Neoplasia, 2(3),
pp. 197-201.
Zhao, J.Q., Glasspool, R.M., Hoare, S.F., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Szatmari, I. and Keith, W.N.
ORCID: https://orcid.org/0000-0001-7862-3580
(2000)
Activation of telomerase RNA gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3.
Neoplasia, 2(6),
pp. 531-539.
Zhao, J.Q., Hoare, S.F., McFarlane, R., Muir, S., Parkinson, E.K., Black, D.M. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1998)
Cloning and characterization of human and mouse telomerase RNA gene promoter sequences.
Oncogene, 16(10),
pp. 1345-1350.
Hoare, S.F., Freeman, C.A., Coutts, J.C., Varley, J.M., James, L. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1997)
Identification of genetic changes associated with drug resistance by reverse in situ hybridization.
British Journal of Cancer, 75(2),
pp. 275-282.
Soder, A.I., Hoare, S.F., Muir, S., Going, J.J., Parkinson, E.K. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1997)
Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer.
Oncogene, 14(9),
pp. 1013-1021.
Soder, A.I., Hoare, S.F., Muire, S., Balmain, A., Parkinson, E.K. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580
(1997)
Mapping of the gene for the mouse telomerase RNA component, Terc, to chromosome 3 by fluorescence in situ hybridization and mouse chromosome painting.
Genomics, 41(2),
pp. 293-294.
(doi: 10.1006/geno.1997.4621)
Book Sections
Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Hoare, S.F.
(2004)
Detection of telomerase hTERT gene expression and its splice variants by RT-PCR.
In: Roulston, J.E. and Bartlett, J.M.S. (eds.)
Molecular Diagnosis of Cancer: Methods and Protocols.
Series: Methods in molecular medicine (97).
Humana Press: Totowa, NJ, USA, pp. 297-309.
ISBN 9781588291608
Research datasets
2010
Lafferty-Whyte, K., Bilsland, A., Hoare, S., Burns, S., Zaffaroni, N., Cairney, C. and Keith, N. (2010) TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression. [Data Collection]