Dr Payam Gammage

  • Senior Lecturer (Institute of Cancer Sciences)

Publications

List by: Type | Date

Jump to: 2020 | 2019 | 2018 | 2016 | 2014 | 2013 | 2012
Number of items: 17.

2020

Bacman, S. R., Gammage, P.A. , Minczuk, M. and Moraes, C.T. (2020) Manipulation of mitochondrial genes and mtDNA heteroplasmy. In: Pon, L. A. and Schon, E. A. (eds.) Mitochondira. 3rd Edition. Series: Methods in cell biology. Academic Press: Amsterdam, pp. 441-487. ISBN 9780128202289 (doi:10.1016/bs.mcb.2019.12.004)

2019

Andreazza, S. et al. (2019) Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. Nature Communications, 10(1), 3280. (doi: 10.1038/s41467-019-10857-y) (PMID:31337756) (PMCID:PMC6650417)

Gammage, P. A. and Frezza, C. (2019) Mitochondrial DNA: the overlooked oncogenome? BMC Biology, 17(1), 53. (doi: 10.1186/s12915-019-0668-y) (PMID:31286943) (PMCID:PMC6615100)

Beard, D. A., Hoitzing, H., Gammage, P. A. , Haute, L. V., Minczuk, M., Johnston, I. G. and Jones, N. S. (2019) Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations. PLoS Computational Biology, 15(6), e1007023. (doi: 10.1371/journal.pcbi.1007023) (PMID:31242175) (PMCID:PMC6615642)

2018

Gammage, P. A. et al. (2018) Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nature Medicine, 24(11), pp. 1691-1695. (doi: 10.1038/s41591-018-0165-9) (PMID:30250142) (PMCID:PMC6225988)

Peeva, V. et al. (2018) Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nature Communications, 9(1), 1727. (doi: 10.1038/s41467-018-04131-w) (PMID:29712893) (PMCID:PMC5928156)

Gammage, P. A. , Moraes, C. T. and Minczuk, M. (2018) Mitochondrial genome engineering: the revolution may not be CRISPR-ized. Trends in Genetics, 34(2), pp. 101-110. (doi: 10.1016/j.tig.2017.11.001) (PMID:29179920) (PMCID:PMC5783712)

Gaude, E. et al. (2018) NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction. Molecular Cell, 69(4), 581-593.e7. (doi: 10.1016/j.molcel.2018.01.034) (PMID:29452638) (PMCID:PMC5823973)

Kullar, P. J. et al. (2018) Heterozygous SSBP1 start loss mutation co-segregates with hearing loss and the m.1555A>G mtDNA variant in a large multigenerational family. Brain, 141(1), pp. 55-62. (doi: 10.1093/brain/awx295) (PMID:29182774) (PMCID:PMC5837410)

Gammage, P. A. and Minczuk, M. (2018) Enhanced manipulation of human mitochondrial DNA heteroplasmy in vitro using tunable mtZFN technology. In: Liu, J. (ed.) Zinc Finger Proteins. Series: Methods in molecular biology (1867). Humana Press: New York, pp. 43-56. ISBN 9781493987986 (doi:10.1007/978-1-4939-8799-3_4)

McCann, B. J., Cox, A., Gammage, P. A. , Stewart, J. B., Zernicka-Goetz, M. and Minczuk, M. (2018) Delivery of mtZFNs into early mouse embryos. In: Liu, J. (ed.) Zinc Finger Proteins. Series: Methods in molecular biology (1867). Humana Press: New York, pp. 215-228. (doi:10.1007/978-1-4939-8799-3_16)

2016

Gammage, P. A. et al. (2016) Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs. Nucleic Acids Research, 44(16), pp. 7804-7816. (doi: 10.1093/nar/gkw676) (PMID:27466392) (PMCID:PMC5027515)

Gammage, P. A. , Van Haute, L. and Minczuk, M. (2016) Engineered mtZFNs for manipulation of human mitochondrial DNA heteroplasmy. In: Mitochondrial DNA. Series: Methods in molecular biology, 1351 (1351). Humana Press: New York, pp. 145-162. ISBN 9781493930395 (doi:10.1007/978-1-4939-3040-1_11)

2014

Gammage, P. A. , Rorbach, J., Vincent, A. I., Rebar, E. J. and Minczuk, M. (2014) Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large‐scale deletions or point mutations. EMBO Molecular Medicine, 6(4), pp. 458-466. (doi: 10.1002/emmm.201303672) (PMID:24567072) (PMCID:PMC3992073)

Rorbach, J., Boesch, P., Gammage, P. A. , Nicholls, T. J.J., Pearce, S. F., Patel, D., Hauser, A., Perocchi, F., Minczuk, M. and Wolin, S. (2014) MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome. Molecular Biology of the Cell, 25(17), pp. 2542-2555. (doi: 10.1091/mbc.e14-01-0014) (PMID:25009282) (PMCID:PMC4148245)

2013

Kazak, L., Reyes, A., Duncan, A. L., Rorbach, J., Wood, S. R., Brea-Calvo, G., Gammage, P. A. , Robinson, A. J., Minczuk, M. and Holt, I. J. (2013) Alternative translation initiation augments the human mitochondrial proteome. Nucleic Acids Research, 41(4), pp. 2354-2369. (doi: 10.1093/nar/gks1347) (PMID:23275553) (PMCID:PMC3575844)

2012

Rorbach, J., Gammage, P. A. and Minczuk, M. (2012) C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome. Nucleic Acids Research, 40(9), pp. 4097-4109. (doi: 10.1093/nar/gkr1282) (PMID:22238376) (PMCID:PMC3351152)

This list was generated on Mon Sep 27 11:48:59 2021 BST.
Number of items: 17.

Articles

Andreazza, S. et al. (2019) Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. Nature Communications, 10(1), 3280. (doi: 10.1038/s41467-019-10857-y) (PMID:31337756) (PMCID:PMC6650417)

Gammage, P. A. and Frezza, C. (2019) Mitochondrial DNA: the overlooked oncogenome? BMC Biology, 17(1), 53. (doi: 10.1186/s12915-019-0668-y) (PMID:31286943) (PMCID:PMC6615100)

Beard, D. A., Hoitzing, H., Gammage, P. A. , Haute, L. V., Minczuk, M., Johnston, I. G. and Jones, N. S. (2019) Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations. PLoS Computational Biology, 15(6), e1007023. (doi: 10.1371/journal.pcbi.1007023) (PMID:31242175) (PMCID:PMC6615642)

Gammage, P. A. et al. (2018) Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nature Medicine, 24(11), pp. 1691-1695. (doi: 10.1038/s41591-018-0165-9) (PMID:30250142) (PMCID:PMC6225988)

Peeva, V. et al. (2018) Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nature Communications, 9(1), 1727. (doi: 10.1038/s41467-018-04131-w) (PMID:29712893) (PMCID:PMC5928156)

Gammage, P. A. , Moraes, C. T. and Minczuk, M. (2018) Mitochondrial genome engineering: the revolution may not be CRISPR-ized. Trends in Genetics, 34(2), pp. 101-110. (doi: 10.1016/j.tig.2017.11.001) (PMID:29179920) (PMCID:PMC5783712)

Gaude, E. et al. (2018) NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction. Molecular Cell, 69(4), 581-593.e7. (doi: 10.1016/j.molcel.2018.01.034) (PMID:29452638) (PMCID:PMC5823973)

Kullar, P. J. et al. (2018) Heterozygous SSBP1 start loss mutation co-segregates with hearing loss and the m.1555A>G mtDNA variant in a large multigenerational family. Brain, 141(1), pp. 55-62. (doi: 10.1093/brain/awx295) (PMID:29182774) (PMCID:PMC5837410)

Gammage, P. A. et al. (2016) Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs. Nucleic Acids Research, 44(16), pp. 7804-7816. (doi: 10.1093/nar/gkw676) (PMID:27466392) (PMCID:PMC5027515)

Gammage, P. A. , Rorbach, J., Vincent, A. I., Rebar, E. J. and Minczuk, M. (2014) Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large‐scale deletions or point mutations. EMBO Molecular Medicine, 6(4), pp. 458-466. (doi: 10.1002/emmm.201303672) (PMID:24567072) (PMCID:PMC3992073)

Rorbach, J., Boesch, P., Gammage, P. A. , Nicholls, T. J.J., Pearce, S. F., Patel, D., Hauser, A., Perocchi, F., Minczuk, M. and Wolin, S. (2014) MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome. Molecular Biology of the Cell, 25(17), pp. 2542-2555. (doi: 10.1091/mbc.e14-01-0014) (PMID:25009282) (PMCID:PMC4148245)

Kazak, L., Reyes, A., Duncan, A. L., Rorbach, J., Wood, S. R., Brea-Calvo, G., Gammage, P. A. , Robinson, A. J., Minczuk, M. and Holt, I. J. (2013) Alternative translation initiation augments the human mitochondrial proteome. Nucleic Acids Research, 41(4), pp. 2354-2369. (doi: 10.1093/nar/gks1347) (PMID:23275553) (PMCID:PMC3575844)

Rorbach, J., Gammage, P. A. and Minczuk, M. (2012) C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome. Nucleic Acids Research, 40(9), pp. 4097-4109. (doi: 10.1093/nar/gkr1282) (PMID:22238376) (PMCID:PMC3351152)

Book Sections

Bacman, S. R., Gammage, P.A. , Minczuk, M. and Moraes, C.T. (2020) Manipulation of mitochondrial genes and mtDNA heteroplasmy. In: Pon, L. A. and Schon, E. A. (eds.) Mitochondira. 3rd Edition. Series: Methods in cell biology. Academic Press: Amsterdam, pp. 441-487. ISBN 9780128202289 (doi:10.1016/bs.mcb.2019.12.004)

Gammage, P. A. and Minczuk, M. (2018) Enhanced manipulation of human mitochondrial DNA heteroplasmy in vitro using tunable mtZFN technology. In: Liu, J. (ed.) Zinc Finger Proteins. Series: Methods in molecular biology (1867). Humana Press: New York, pp. 43-56. ISBN 9781493987986 (doi:10.1007/978-1-4939-8799-3_4)

McCann, B. J., Cox, A., Gammage, P. A. , Stewart, J. B., Zernicka-Goetz, M. and Minczuk, M. (2018) Delivery of mtZFNs into early mouse embryos. In: Liu, J. (ed.) Zinc Finger Proteins. Series: Methods in molecular biology (1867). Humana Press: New York, pp. 215-228. (doi:10.1007/978-1-4939-8799-3_16)

Gammage, P. A. , Van Haute, L. and Minczuk, M. (2016) Engineered mtZFNs for manipulation of human mitochondrial DNA heteroplasmy. In: Mitochondrial DNA. Series: Methods in molecular biology, 1351 (1351). Humana Press: New York, pp. 145-162. ISBN 9781493930395 (doi:10.1007/978-1-4939-3040-1_11)

This list was generated on Mon Sep 27 11:48:59 2021 BST.