Professor Joanne Edwards

  • Professor of Translational Cancer Pathology (Therapeutic Science Research)
  • Director of Education (School of Cancer Sciences)

telephone: 01413307244
email: Joanne.Edwards@glasgow.ac.uk
pronouns: She/her/hers

Wolfson Wohl Building, Garscube Estate, Switchback Road, Glasgow, G61 1qh

Import to contacts

ORCID iDhttps://orcid.org/0000-0002-7192-6906

Biography

Joanne Edwards is Professor of Translational Cancer Pathology and Principal Investigator at the School of Cancer Sciences, University of Glasgow. She is also Director of Education for the School of Cancer Sciences, Lead of the Colorectal Cancer Theme for the Cancer Research UK Scotland Centre, Director of the Glasgow Tissue Research Facility and Director of the Integrated Technologies for Improved Polyp Surveillance (INCISE) project.

She received her PhD from the University of St Andrews before moving to Glasgow in 1997. With over 20 years of experience in cancer biomarker research and therapeutics, her research focuses on colorectal and breast cancer. She has an H-index of 71, has published more than 200 scientific papers, with over 17,000 citations, and has established an international network of collaborators.

She has developed unique patient tissue cohorts with extensive linked clinical data across a breadth of solid tumours, gaining an international reputation for her expertise in developing biomarkers for personalised patient care. Notably, despite being a non-clinical researcher, her work has led to her election as a Fellow of the Royal College of Pathologists.

Joanne leads a multidisciplinary team of scientists and surgeons and has supervised over 20 PhD students. As a mentor, she strives to support the next generation of cancer researchers and inspire them through their educational careers as PhD students and post-doctoral scientists.

 

Research interests

Joanne's work aims to better understand the determinants of short- and long-term outcomes in patients with colorectal and breast cancer, particularly the relationship between local and systemic inflammatory responses, the tumour microenvironment and cell signalling, with the goal of integrating this knowledge into routine clinical management.

Central to this work is the team’s large collection of tissue microarrays, which allow for the identification of clinically relevant prognostic and predictive biomarkers. In more recent years, her research has expanded to include AI computational pathology, genomics, transcriptomics, spatial biology and the development of human models such as tissue explants, patient-derived organoids and patient-derived co-culture models.

The overarching aim of the team's research is to develop novel treatment strategies to establish a personalised medicine approach for colorectal and breast cancer.

Research groups

Publications

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Number of items: 225.

2025

Woraharn, W. et al. (2025) Investigation of three alternative histopathological scoring methods at the invasive tumour front in colorectal cancer. Journal of Pathology: Clinical Research, 11(3), e70031. (doi: 10.1002/2056-4538.70031)

Thompson, Joshua J., MacLeod, Nicholas, Will, Sarah, O'Rourke, Fraser, McGovern, Josh, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dolan, Ross D. ORCID logoORCID: https://orcid.org/0000-0002-5272-5906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2025) The prognostic value of a laboratory cachexia score (LCAS) defined by LDH, CRP and albumin in patients with advanced lung cancer. BMC Cancer, 25, 543. (doi: 10.1186/s12885-025-13426-3) (PMID:40133911) (PMCID:PMC11938618)

Dolan, R. D. et al. (2025) The relationship between tumour necrosis, systemic inflammation, body composition and survival in patients with colon cancer. BJC Reports, 3(1), 7. (doi: 10.1038/s44276-024-00119-w) (PMID:39910331)

Iwata, T. et al. (2025) Does Immune Suppression in the Pre-malignant Microenvironment of Colorectal Neoplastic Lesions Associate with Development of Metachronous Polyp and Cancer Risk? 216th Scientific Meeting of the Pathological Society of Great Britain & Ireland, Royal Society of Medicine, London UK, 21-22 Jan 2025.

Mathews, C. et al. (2025) Retrospective cohort study: scope for improvement - barriers to post-polypectomy surveillance in the integrated technologies for improved polyp surveillance cohort. Alimentary Pharmacology and Therapeutics, (doi: 10.1111/apt.18514) (Early Online Publication)

2024

Pennel, K. et al. (2024) IL6 and IL6R as prognostic biomarkers in colorectal cancer. Biomolecules, 14(12), 1629. (doi: 10.3390/biom14121629)

Shamis, S. A.K. et al. (2024) Elucidation of dysregulated pathways associated with hypoxia in oestrogen receptor-negative breast cancer. Cancer Medicine, 13(23), e70274. (doi: 10.1002/cam4.70274) (PMID:39660488) (PMCID:PMC11632397)

Galbraith, N. J. et al. (2024) TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer. Translational Oncology, 48, 102064. (doi: 10.1016/j.tranon.2024.102064) (PMID:39068768)

Knight, Katrina, Bigley, Christopher, Pennel, Kathryn, Hay, Jennifer, Maka, Noori, McMillan, Donald ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Park, James ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) The Glasgow Microenvironment Score: an exemplar of contemporary biomarker evolution in colorectal cancer. Journal of Pathology: Clinical Research, 10, e12385. (doi: 10.1002/2056-4538.12385) (PMID:38853386)

Thompson, Joshua, McGovern, Josh, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dolan, Ross D. ORCID logoORCID: https://orcid.org/0000-0002-5272-5906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2024) The relationship between LDH and GLIM criteria for cancer cachexia: systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 199, 104378. (doi: 10.1016/j.critrevonc.2024.104378) (PMID:38754770)

McKenzie, Molly, Lian, Guang-Yu, Pennel, Kathryn A.F., Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Jamieson, Nigel B. ORCID logoORCID: https://orcid.org/0000-0002-9552-4725 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) NFκB signalling in colorectal cancer: examining the central dogma of IKKα and IKKβ signalling. Heliyon, 10(12), e32904. (doi: 10.1016/j.heliyon.2024.e32904) (PMID:38975078) (PMCID:PMC11226910)

Hatthakarnkul, P. et al. (2024) Histopathological tumour microenvironment score independently predicts outcome in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 10(3), e12374. (doi: 10.1002/2056-4538.12374) (PMID:38650367) (PMCID:PMC11035902)

Pennel, Kathryn, Dutton, Louise ORCID logoORCID: https://orcid.org/0000-0002-9336-7826, Melissourgou-Syka, Lydia ORCID logoORCID: https://orcid.org/0000-0002-0926-2328, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Birch, Joanna ORCID logoORCID: https://orcid.org/0000-0001-9522-8435 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) Novel radiation and targeted therapy combinations for improving rectal cancer outcomes. Expert Reviews in Molecular Medicine, 26, e14. (doi: 10.1017/erm.2024.15) (PMID:38623751) (PMCID:PMC11140547)

Domingo, E. et al. (2024) Prognostic and predictive value of Immunoscore in stage III colorectal cancer: pooled analysis of 2,608 cases from the SCOT and IDEA-HORG studies. Journal of Clinical Oncology, (doi: 10.1200/JCO.23.01648) (PMID:38484206) (Early Online Publication)

Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)

Frei, A. L. et al. (2024) Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II–III colorectal cancer from the SCOT and QUASAR 2 trials: A retrospective analysis. Lancet Oncology, 25(2), pp. 198-211. (doi: 10.1016/S1470-2045(23)00560-0) (PMID:38301689)

Hillson, Lily Victoria Sarah, McCulloch, Ashley Kathryn, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dunne, Philip David, O'Cathail, Sean Michael ORCID logoORCID: https://orcid.org/0000-0001-5574-9199 and Roxburgh, Campbell Stuart ORCID logoORCID: https://orcid.org/0000-0002-2649-6695 (2024) Radiation-induced changes in gene expression in rectal cancer specimens. Clinical and Translational Oncology, (doi: 10.1007/s12094-023-03361-9) (PMID:38243085) (Early Online Publication)

Brouwer, N.P.M. et al. (2024) The complexity of shapes: how the circularity of tumor nodules impacts prognosis in colorectal cancer. Modern Pathology, 37(1), 100376. (doi: 10.1016/j.modpat.2023.100376) (PMID:37926423)

Shamis, Suad Ahmad Khalifa, Savioli, Francesca, Ammar, Aula ORCID logoORCID: https://orcid.org/0000-0002-0375-062X, Al-Badran, Sara S.F., Hatthakarnkul, Phimmada, Leslie, Holly ORCID logoORCID: https://orcid.org/0000-0001-8898-3600, Mallon, Elizabeth, Jamieson, Nigel B. ORCID logoORCID: https://orcid.org/0000-0002-9552-4725, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) Spatial transcriptomic analysis of tumour with high and low CAIX expression in TNBC tissue samples using GeoMx™ RNA assay. Histology and Histopathology: Cellular and Molecular Biology, 39, pp. 177-200. (doi: 10.14670/HH-18-655) (PMID:37681672)

2023

Beach, C. et al. (2023) Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1. Journal of Clinical Investigation, 133(23), e168277. (doi: 10.1172/JCI168277) (PMID:37824211) (PMCID:PMC10688992)

Frei, A. L. et al. (2023) Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets. Journal of Pathology: Clinical Research, 9(6), pp. 449-463. (doi: 10.1002/cjp2.342) (PMID:37697694) (PMCID:PMC10556275)

Suzuki, T. et al. (2023) β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer. Cancer Immunology Research, 11(8), pp. 1137-1155. (doi: 10.1158/2326-6066.CIR-22-0644) (PMID:37309673) (PMCID:PMC10398359)

Vande Voorde, J. et al. (2023) Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target. Nature Metabolism, 5(8), pp. 1303-1318. (doi: 10.1038/s42255-023-00857-0) (PMID:37580540) (PMCID:PMC10447251)

Hatthakarnkul, P. et al. (2023) Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer. Journal of Cancer, 14(10), pp. 1837-1847. (doi: 10.7150/jca.83910) (PMID:37476187) (PMCID:PMC10355195)

Johnstone, Mark S., Stoops, Reiss, Lynch, Gerard, Hay, Jennifer, Jawny, Jakub, Sloan, William, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McSorley, Stephen T. ORCID logoORCID: https://orcid.org/0000-0002-5459-8445 (2023) Risk stratification for the detection of metachronous polyps after bowel screening polypectomy: clinical outcomes from the Integrated Technologies for Improved Polyp Surveillance (INCISE) study cohort. BJS Open, 7(3), zrad034. (doi: 10.1093/bjsopen/zrad034) (PMID:37158435) (PMCID:PMC10167706)

Pennel, Kathryn, Morrow, Elizabeth, Hatthakarnkul, Phimmada, Leslie, Holly ORCID logoORCID: https://orcid.org/0000-0001-8898-3600, Mallon, Elizabeth, Andersen, Ditte, Jamieson, Nigel ORCID logoORCID: https://orcid.org/0000-0002-9552-4725, McMillan, Donald ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Roseweir, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2023) High expression of STAT3 within the tumour-associated stroma predicts poor outcome in breast cancer patients. Cancer Medicine, 12(12), pp. 13225-13240. (doi: 10.1002/cam4.6014) (PMID:37199043) (PMCID:PMC10315752)

Shamis, Suad A.K., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2023) The relationship between carbonic anhydrase IX (CAIX) and patient survival in breast cancer: systematic review and meta-analysis. Diagnostic Pathology, 18, 46. (doi: 10.1186/s13000-023-01325-9) (PMID:37061698) (PMCID:PMC10105416)

Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)

Numprasit, Warapan, Yangngam, Supaporn, Prasopsiri, Jaturawitt, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Thuwajit, Chanitra (2023) Carbonic anhydrase IX-related tumoral hypoxia predicts worse prognosis in breast cancer: a systematic review and meta-analysis. Frontiers in Medicine, 10, 1087270. (doi: 10.3389/fmed.2023.1087270) (PMID:37007798) (PMCID:PMC10063856)

Alexander, P.G., van Wyk, H.C. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, Pennel, K.A.F., Hay, J., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Roxburgh, C.S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Park, J.H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037 (2023) The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer. British Journal of Cancer, 128(4), pp. 556-567. (doi: 10.1038/s41416-022-02069-x) (PMID:36476660) (PMCID:PMC9938140)

Tandon, Vasudha, Moreno, Rita, Allmeroth, Kira, Quinn, Jean ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Wiley, Sandra E., Nicely, Lynden G., Denzel, Martin S., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, de la Vega, Laureano and Banerjee, Sourav (2023) Dual inhibition of HSF1 and DYRK2 impedes cancer progression. Bioscience Reports, 34(1), BSR2022210. (doi: 10.1042/BSR20222102) (PMID:36622366) (PMCID:PMC9894012)

2022

Patel, Meera, McAllister, Milly, Nagaraju, Raghavendar, Al Badran, Sara Samir Foad, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McBain, Andrew J., Barriuso, Jorge and Aziz, Omer (2022) The intestinal microbiota in colorectal cancer metastasis - Passive observer or key player? Critical Reviews in Oncology/Hematology, 180, 103856. (doi: 10.1016/j.critrevonc.2022.103856) (PMID:36257533)

Savioli, Francesca, Morrow, Elizabeth S., Dolan, Ross D. ORCID logoORCID: https://orcid.org/0000-0002-5272-5906, Romics, Laszlo, Lannigan, Alison, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2022) Prognostic role of preoperative circulating systemic inflammatory response markers in primary breast cancer: meta-analysis. British Journal of Surgery, 109(12), pp. 1206-1215. (doi: 10.1093/bjs/znac319) (PMID:36130112)

Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)

Alexander, P. G. et al. (2022) The relationship between the Glasgow Microenvironment Score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer. Human Pathology, 127, pp. 1-11. (doi: 10.1016/j.humpath.2022.05.012) (PMID:35623467)

Yangngam, Supaporn, Prasopsiri, Jaturawitt, Hatthakarnkul, Phimmada, Thongchot, Suyanee, Thuwajit, Peti, Yenchitsomanus, Pa-thai, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Thuwajit, Chanitra (2022) Cellular localization of nucleolin determines the prognosis in cancers: a meta-analysis. Journal of Molecular Medicine, 100(8), pp. 1145-1157. (doi: 10.1007/s00109-022-02228-w) (PMID:35861882) (PMCID:PMC9329415)

Shamis, Suad A.K., Quinn, Jean ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Mallon, Elizabeth E.A., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2022) The relationship between the tumor cell expression of hypoxic markers and survival in patients with ER-positive invasive ductal breast cancer. Journal of Histochemistry and Cytochemistry, 70(7), pp. 479-494. (doi: 10.1369/00221554221110280) (PMID:35792080)

Patel, M. et al. (2022) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. British Journal of Cancer, 126(12), pp. 1704-1714. (doi: 10.1038/s41416-022-01729-2) (PMID:35173303) (PMCID:PMC9174220)

Hatthakarnkul, Phimmada, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Ammar, Aula ORCID logoORCID: https://orcid.org/0000-0002-0375-062X, Lynch, Gerard, Van Wyk, Hester ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Thuwajit, Chanitra and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2022) Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer. Clinical Science, 136(8), pp. 521-535. (doi: 10.1042/CS20210886) (PMID:35445707)

Blomme, A. et al. (2022) THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer. EMBO Molecular Medicine, 14(3), e14764. (doi: 10.15252/emmm.202114764) (PMID:35014179) (PMCID:PMC8899912)

2021

Lampis, A. et al. (2021) MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer. Cell Death and Differentiation, 28, pp. 2970-2982. (doi: 10.1038/s41418-021-00820-0) (PMID:34226680) (PMCID:PMC8481293)

Hanna, C. R. et al. (2021) Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT). Radiation Oncology, 16, 163. (doi: 10.1186/s13014-021-01888-1) (PMID:34446053)

Johnstone, Mark S., Lynch, Gerard, Park, James ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, McSorley, Stephen ORCID logoORCID: https://orcid.org/0000-0002-5459-8445 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) Novel methods of risk stratifying patients for metachronous, pre-malignant colorectal polyps: a systematic review. Critical Reviews in Oncology/Haematology, 164, 103421. (doi: 10.1016/j.critrevonc.2021.103421) (PMID:34246774)

Mansouri, David ORCID logoORCID: https://orcid.org/0000-0002-9157-6085, McSorley, Stephen T. ORCID logoORCID: https://orcid.org/0000-0002-5459-8445, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Orange, Clare, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) The inflammatory microenvironment in screen-detected premaligant adenomatous polyps: early results from the integrated technologies for improved polyp surveillance (INCISE) project. European Journal of Gastroenterology and Hepatology, 33(7), pp. 983-989. (doi: 10.1097/MEG.0000000000002202) (PMID:34034277)

Matly, Amna, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) The relationship between β-catenin and patient survival in colorectal cancer systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 163, 103337. (doi: 10.1016/j.critrevonc.2021.103337) (PMID:33992802)

Knight, J. R.P. et al. (2021) MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression. Cancer Discovery, 11(5), pp. 1228-1247. (doi: 10.1158/2159-8290.CD-20-0652) (PMID:33328217)

Moreno, Rita, Banerjee, Sourav, Jackson, Angus W, Quinn, Jean ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Baillie, Gregg, Dixon, Jack E, Dinkova-Kostova, Albena T, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and de la Vega, Laureano (2021) The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress. Cell Death and Differentiation, 28(5), pp. 1563-1578. (doi: 10.1038/s41418-020-00686-8) (PMID:33268814)

Al-Badran, S. S.F. et al. (2021) Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 7(2), pp. 121-134. (doi: 10.1002/cjp2.193) (PMID:33338327)

Shamis, Suad Ahmad Khalifa, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) The relationship between Hypoxia-inducible factor 1α (HIF-1α) and patient survival in breast cancer: systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 159, 103231. (doi: 10.1016/j.critrevonc.2021.103231) (PMID:33482350)

Hatthakarnkul, Phimmada, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Matly, Amna Ahmed Mohemmd, Ammar, Aula ORCID logoORCID: https://orcid.org/0000-0002-0375-062X, Van Wyk, Hester C. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) Systematic review of tumour budding and association with common mutations in patients with colorectal cancer. Critical Reviews in Oncology/Hematology, 167, 103490. (doi: 10.1016/j.critrevonc.2021.103490) (PMID:34619332)

2020

McAllister, Milly J., McCall, Pamela, Dickson, Ashley, Underwood, Mark A., Andersen, Ditte, Holmes, Elizabeth, Market, Elke, Leung, Hing Y. ORCID logoORCID: https://orcid.org/0000-0002-3933-3975 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2020) Androgen receptor phosphorylation at serine 81 and serine 213 in castrate-resistant prostate cancer. Prostate Cancer and Prostatic Diseases, 23(4), pp. 596-606. (doi: 10.1038/s41391-020-0235-1) (PMID:32358577)

McAllister, Milly, Constancio, Vera, Patek, Samantha, Gan, Hao, Bailey, Peter ORCID logoORCID: https://orcid.org/0000-0002-0857-2041, Wheadon, Helen ORCID logoORCID: https://orcid.org/0000-0001-9902-3170, Underwood, Mark, Leung, Hing ORCID logoORCID: https://orcid.org/0000-0002-3933-3975 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2020) Inflammatory infiltration is associated with AR expression and poor prognosis in hormone naïve prostate cancer. Prostate, 80(15), pp. 1353-1364. (doi: 10.1002/pros.24064) (PMID:32846021)

Savioli, F., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McMillan, D. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Stallard, S., Doughty, J. and Romics, L. (2020) The effect of postoperative complications on survival and recurrence after surgery for breast cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 155, 103075. (doi: 10.1016/j.critrevonc.2020.103075) (PMID:32987333)

Suzuki, Toshiyasu, Hayman, Liam, Kilbey, Anna, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Coffelt, Seth B. ORCID logoORCID: https://orcid.org/0000-0003-2257-2862 (2020) Gut γδ T cells as guardians, disruptors and instigators of cancer. Immunological Reviews, 298(1), pp. 198-217. (doi: 10.1111/imr.12916) (PMID:32840001)

Alexander, P.G. et al. (2020) The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British Journal of Cancer, 124, pp. 786-796. (doi: 10.1038/s41416-020-01168-x) (PMID:33223535)

Montes, M. et al. (2020) Determining the prognostic significance of IKKα in prostate cancer. Prostate, 80(14), pp. 1188-1202. (doi: 10.1002/pros.24045) (PMID:33258506)

Roseweir, A. K. et al. (2020) Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. Journal of Pathology: Clinical Research, 6(4), pp. 283-296. (doi: 10.1002/cjp2.171) (PMID:32401426) (PMCID:PMC7578335)

Torrente, L. et al. (2020) High NRF2 levels correlate with poor prognosis in colorectal cancer patients and with sensitivity to the kinase inhibitor AT9283 in vitro. Biomolecules, 10(10), 1365. (doi: 10.3390/biom10101365) (PMID:32992842) (PMCID:PMC7600603)

Rooney, N. et al. (2020) RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome. Cancer Research, 80(11), pp. 2325-2339. (doi: 10.1158/0008-5472.CAN-19-3870) (PMID:32156779)

Patel, R. et al. (2020) Activation of β-catenin cooperates with loss of Pten to drive AR-independent castration-resistant prostate cancer. Cancer Research, 80(3), pp. 576-590. (doi: 10.1158/0008-5472.CAN-19-1684) (PMID:31719098)

Loveridge, C. J. et al. (2020) BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene, 39, pp. 1797-1806. (doi: 10.1038/s41388-019-1106-x) (PMID:31740786) (PMCID:PMC7033044)

2019

Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, van Wyk, Hester ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Orange, Clare, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Roxburgh, Campbell S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695 (2019) Pre-operative, biopsy-based assessment of the tumour microenvironment in patients with primary operable colorectal cancer. Journal of Pathology: Clinical Research, 6(1), pp. 30-39. (doi: 10.1002/cjp2.143) (PMID:31486287) (PMCID:PMC6966701)

Andisha, Najla M., McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Gujam, Fadia J.A., Roseweir, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) The relationship between phosphorylation status of focal adhesion kinases, molecular subtypes, tumour microenvironment and survival in patients with primary operable ductal breast cancer. Cellular Signalling, 60, pp. 91-99. (doi: 10.1016/j.cellsig.2019.04.006) (PMID:30981841)

Khongthong, Phungern, Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) The NF-KB pathway and endocrine therapy resistance in breast cancer. Endocrine-Related Cancer, 26(6), R369-R380. (doi: 10.1530/ERC-19-0087) (PMID:32013374)

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Clark, Jennifer, McSorley, Stephen T. ORCID logoORCID: https://orcid.org/0000-0002-5459-8445, vanWyk, Hester C. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)

McAllister, Milly J., Underwood, Mark A., Leung, Hing Y. ORCID logoORCID: https://orcid.org/0000-0002-3933-3975 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) A review on the interactions between the tumour microenvironment and androgen receptor signaling in prostate cancer. Translational Research, 206, pp. 91-106. (doi: 10.1016/j.trsl.2018.11.004) (PMID:30528321)

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Powell, Arfon G.M.T., Horstman, Sheryl L., Inthagard, Jitwadee, Park, James A. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer. Cellular Signalling, 56, pp. 15-22. (doi: 10.1016/j.cellsig.2019.01.007) (PMID:30684564)

Pennel, Kathryn A.F., Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) Signal interaction between the tumour and inflammatory cells in patients with gastrointestinal cancer: implications for treatment. Cellular Signalling, 54, pp. 81-90. (doi: 10.1016/j.cellsig.2018.11.013) (PMID:30453014)

Inthagard, Jitwadee, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 (2019) Immunotherapy: enhancement the efficacy of this promising therapeutic in multiple cancers. Clinical Science, 133(2), pp. 181-193. (doi: 10.1042/CS20181003) (PMID:30659159)

Morrow, Elizabeth, Roseweir, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) The role of gamma delta T lymphocytes in breast cancer: a review. Translational Research, 203, pp. 88-96. (doi: 10.1016/j.trsl.2018.08.005) (PMID:30194922)

Roseweir, A.K. et al. (2019) A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer. International Journal of Cancer, 144(1), pp. 150-159. (doi: 10.1002/ijc.31739) (PMID:29992570)

Van Wyk, Hester ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, Roseweir, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Alexander, Peter ORCID logoORCID: https://orcid.org/0000-0002-6123-4922, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Horgan, Paul ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2019) The relationship between tumour budding, tumour microenvironment and survival in patients with primary operable colorectal cancer. Annals of Surgical Oncology, 26, pp. 4397-4404. (doi: 10.1245/s10434-019-07931-6) (PMID:31605345) (PMCID:PMC6863941)

2018

Mulholland, Theresa, McAllister, Milly, Patek, Samantha, Flint, David, Underwood, Mark, Sim, Alexander, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Zagnoni, Michele (2018) Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient. Scientific Reports, 8, 14672. (doi: 10.1038/s41598-018-33055-0) (PMID:30279484) (PMCID:PMC6168499)

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2018) Reply to comment of "ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer". British Journal of Cancer, 119(7), p. 909. (doi: 10.1038/s41416-018-0275-7) (PMID:30297771) (PMCID:PMC6189185)

Paul, Andrew, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Pepper, Christopher and Mackay, Simon (2018) Inhibitory-κB kinase (IKK) α and nuclear factor-κB (NFκB)-inducing kinase (NIK) as anti-cancer drug targets. Cells, 7(10), 176. (doi: 10.3390/cells7100176) (PMID:30347849) (PMCID:PMC6210445)

Lua, Joanne, Qayyum, Tahir, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 (2018) The prognostic role of the non-canonical nuclear factor-kappa B pathway in renal cell carcinoma patients. Urologia Internationalis, 101(2), pp. 190-196. (doi: 10.1159/000489816) (PMID:30089311)

Gujam, Fadia, Dickson, Katie, McCall, Pamela, McMillan, Donald ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2018) The relationship between androgen receptor, components of tumour microenvironment and survival in breast cancer molecular subtypes. Cancer Therapy and Oncology, 11(3), 555814.

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Halcrow, Elaine S., Chichilo, Sergey, Powell, Arfon G.M.T., McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2018) ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer. British Journal of Cancer, 119, pp. 323-329. (doi: 10.1038/s41416-018-0174-y) (PMID:29988110) (PMCID:PMC6070918)

Patel, Meera, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2018) NF-κB pathways in the development and progression of colorectal cancer. Translational Research, 197, pp. 43-56. (doi: 10.1016/j.trsl.2018.02.002) (PMID:29550444)

Roseweir, A. K. et al. (2018) Predictive biomarkers for endocrine therapy: retrospective study in Tamoxifen and Exemestane Adjuvant Multinational (TEAM) trial. Journal of the National Cancer Institute, 110(6), pp. 616-627. (doi: 10.1093/jnci/djx255) (PMID:29917140)

Patel, R. et al. (2018) Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1. EMBO Molecular Medicine, 10(4), e8347. (doi: 10.15252/emmm.201708347) (PMID:29540470) (PMCID:PMC5887544)

Patel, Meera, McSorley, Stephen T. ORCID logoORCID: https://orcid.org/0000-0002-5459-8445, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Roxburgh, Campbell S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, Joann ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2018) The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer. British Journal of Cancer, 118(5), pp. 705-712. (doi: 10.1038/bjc.2017.441) (PMID:29337962) (PMCID:PMC5846060)

Campbell, K. J. et al. (2018) MCL-1 is a prognostic indicator and drug target in breast cancer. Cell Death and Disease, 9, 19. (doi: 10.1038/s41419-017-0035-2) (PMID:29339815) (PMCID:PMC5833338)

Bilsland, Alan ORCID logoORCID: https://orcid.org/0000-0003-0957-3908, Kelly, Caroline ORCID logoORCID: https://orcid.org/0000-0002-5330-7888, Roccisana, Jennifer, Paul, James ORCID logoORCID: https://orcid.org/0000-0001-7367-5816, Jones, Robert ORCID logoORCID: https://orcid.org/0000-0002-2904-6980, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Roseweir, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Stein, Torsten ORCID logoORCID: https://orcid.org/0000-0002-9946-1549 and West, Katherine ORCID logoORCID: https://orcid.org/0000-0002-5994-8969 (2018) An Exploratory Study on the Use of Game-based Learning Using Microsoft Kinect to Teach Oncology Phase I Clinical Trial Designs. 2018 NCRI Cancer Conference, Glasgow, UK, 04-06 Nov 2018. (doi: 10.1038/s41416-018-0299-z)

McClurg, Urszula L., Chit, Nay C.T.H., Azizyan, Mahsa, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Nabbi, Arash, Riabowol, Karl T., Nakjang, Sirintra, McCracken, Stuart R. and Robson, Craig N. (2018) Molecular mechanism of the TP53-MDM2-AR-AKT signalling network regulation by USP12. Oncogene, 37, pp. 4679-4691. (doi: 10.1038/s41388-018-0283-3) (PMID:29755129)

Sierra Gonzalez, P. et al. (2018) Mannose impairs tumour growth and enhances chemotherapy. Nature, 563, pp. 719-723. (doi: 10.1038/s41586-018-0729-3) (PMID:30464341)

2017

Anthony, N. G. et al. (2017) Inhibitory Kappa B kinse α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers. Journal of Medicinal Chemistry, 60(16), pp. 7043-7066. (doi: 10.1021/acs.jmedchem.7b00484) (PMID:28737909) (PMCID:PMC5578373)

Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Roxburgh, Campbell S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2017) In reply to "Hynes S.O. et al. Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population-based study". Histopathology, 71(2), pp. 326-327. (doi: 10.1111/his.13195) (PMID:28226191)

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, McCall, Pamela, Scott, Alison, Liew, Benjamin, Lim, Zhi, Mallon, Elizabeth A. and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2017) Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer. Oncotarget, 8(23), pp. 37172-37185. (doi: 10.18632/oncotarget.16420) (PMID:28415597) (PMCID:PMC5514900)

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2017) Colorectal cancer subtypes: Translation to routine clinical pathology. Cancer Treatment Reviews, 57, pp. 1-7. (doi: 10.1016/j.ctrv.2017.04.006) (PMID:28505475)

Park, J.H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Van Wyk, H. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, Roxburgh, C.S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2017) Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer. British Journal of Cancer, 116, pp. 1444-1450. (doi: 10.1038/bjc.2017.108)

Bennett, Lindsay, Mallon, Elizabeth A., Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Paul, Andrew, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2017) The relationship between members of the canonical NF-KB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget, 8(20), pp. 33002-33013. (doi: 10.18632/oncotarget.16031) (PMID:28423692)

Dreyer, Stephan B., Powell, Arfon G.M.T., McSorley, Stephen T. ORCID logoORCID: https://orcid.org/0000-0002-5459-8445, Waterston, Ashita, Going, James J., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 (2017) The pretreatment systemic inflammatory response is an important determinant of poor pathologic response for patients undergoing neoadjuvant therapy for rectal cancer. Annals of Surgical Oncology, 24(5), pp. 1295-1303. (doi: 10.1245/s10434-016-5684-3) (PMID:27873100)

Bennett, Lindsay, Quinn, Jean ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, McCall, Pamela, Mallon, Elizabeth A., Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Paul, Andrew and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2017) High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer. International Journal of Cancer, 140(7), pp. 1633-1644. (doi: 10.1002/ijc.30578) (PMID:28006839)

Cheng, Kelvin K.W., Dickson, Ashley, Gujam, Fadia J.A., McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2017) The relationship between oestrogen receptor-alpha phosphorylation and the tumour microenvironment in patients with primary operable ductal breast cancer. Histopathology, 70(5), pp. 782-797. (doi: 10.1111/his.13134) (PMID:27891654)

Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Van Wyk, Hester C., McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Clark, Jennifer, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2017) Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host. Clinical Cancer Research, 23(7), pp. 1698-1709. (doi: 10.1158/1078-0432.CCR-16-1416) (PMID:27678454)

Diaz-Vera, Jesica, Palmer, Sarah, Hernandez-Fernaud, Juan Ramon, Dornier, Emmanuel, Mitchell, Louise E., MacPherson, Iain ORCID logoORCID: https://orcid.org/0000-0003-4295-8885, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Zanivan, Sara and Norman, Jim C. ORCID logoORCID: https://orcid.org/0000-0002-0098-3014 (2017) A proteomic approach to identify endosomal cargoes controlling cancer invasiveness. Journal of Cell Science, 130(4), pp. 697-711. (doi: 10.1242/jcs.190835) (PMID:28062852)

2016

Patek, S.C., Willder, J.M., Heng, J.S., Taylor, B., Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Leung, H.Y. ORCID logoORCID: https://orcid.org/0000-0002-3933-3975, Underwood, M.A. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2016) Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients. Oncotarget, 8(3), pp. 4875-4887. (doi: 10.18632/oncotarget.13608) (PMID:27902483)

Hatziieremia, Sophia, Mohammed, Zahra, McCall, Pamela, Willder, Jennifer M., Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Underwood, Mark A. and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2016) Loss of signal transducer and activator of transcription 1 is associated with prostate cancer recurrence. Molecular Carcinogenesis, 55(11), pp. 1667-1677. (doi: 10.1002/mc.22417) (PMID:26495772)

Gujam, Fadia J.A., McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2016) The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget, 7(47), pp. 77607-77621. (doi: 10.18632/oncotarget.12730) (PMID:27769057)

Campbell, Esther J., Tesson, Mathias, Doogan, Flora, Mohammed, Zahra M.A., Mallon, Elizabeth and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2016) The combined endocrine receptor in breast cancer, a novel approach to traditional hormone receptor interpretation and a better discriminator of outcome than ER and PR alone. British Journal of Cancer, 115(8), pp. 967-973. (doi: 10.1038/bjc.2016.206) (PMID:27657341)

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Powell, Arfon G.M.T., Bennett, Lindsay, Van Wyk, Hester C. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, Park, James ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2016) Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer. Oncotarget, 7(43), pp. 70601-70612. (doi: 10.18632/oncotarget.12134) (PMID:27661110)

Ahmad, I. et al. (2016) Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer. Proceedings of the National Academy of Sciences of the United States of America, 113(29), pp. 8290-8295. (doi: 10.1073/pnas.1601571113) (PMID:27357679) (PMCID:PMC4961202)

van Wyk, Hester C. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Going, James J. (2016) The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer. British Journal of Cancer, 115(2), pp. 156-163. (doi: 10.1038/bjc.2016.173) (PMID:27299960)

Park, J. H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, McMillan, D. C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Horgan, P. G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Roxburgh, Campbell S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695 (2016) Comparison of the prognostic value of measures of the tumor inflammatory cell infiltrate and tumor-associated stroma in patients with primary operable colorectal cancer. OncoImmunology, 5(3), e1098801. (doi: 10.1080/2162402X.2015.1098801)

Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Powell, Arfon G., Roxburgh, Campbell S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald c. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2016) Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment. British Journal of Cancer, 114, pp. 562-570. (doi: 10.1038/bjc.2016.17) (PMID:26859693)

Roseweir, Antonia K. ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Qayyum, Tahir, Lim, Zhi, Hammond, Rachel, MacDonald, Alasdair I., Fraser, Siobhan, Oades, Grenville M., Aitchison, Michael, Jones, Robert J. ORCID logoORCID: https://orcid.org/0000-0002-2904-6980 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2016) Nuclear expression of Lyn, a Src family kinase member, is associated with poor prognosis in renal cancer patients. BMC Cancer, 16, p. 229. (doi: 10.1186/s12885-016-2254-9) (PMID:26984511) (PMCID:PMC4794832)

2015

Gujam, F.J.A., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Mohammed, Z.M.A., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Going, J.J. (2015) The relationship between tumour budding, the tumour microenvironment and survival in patients with invasive ductal breast cancer. British Journal of Cancer, 113(7), pp. 1066-1074. (doi: 10.1038/bjc.2015.287) (PMID:26263482)

Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Powell, Arfon G., Richards, Colin H., Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Roxburgh, Campbell S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695 (2015) Evaluation of a tumor microenvironment-based prognostic score in primary operable colorectal cancer. Clinical Cancer Research, 21(4), pp. 882-888. (doi: 10.1158/1078-0432.CCR-14-1686) (PMID:25473000)

Mardilovich, Katerina, Gabrielsen, Mads ORCID logoORCID: https://orcid.org/0000-0002-9848-2276, McGarry, Lynn, Orange, Clare, Patel, Rachana, Shanks, Emma, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Olson, Michael F. ORCID logoORCID: https://orcid.org/0000-0003-3428-3507 (2015) Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Molecular Cancer Therapeutics, 14(1), pp. 246-258. (doi: 10.1158/1535-7163.MCT-14-0447)

2014

Gujam, Fadia J.A., Going, James J., Mohammed, Zahra M.A., Orange, Clare, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2014) Immunohistochemical detection improves the prognostic value of lymphatic and blood vessel invasion in primary ductal breast cancer. BMC Cancer, 14, 676. (doi: 10.1186/1471-2407-14-676) (PMID:25234410) (PMCID:PMC4177173)

MacPherson, I. R. et al. (2014) CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer. Journal of Cell Science, 127(18), pp. 3893-3901. (doi: 10.1242/jcs.135947) (PMID:25015290)

Rajan, P. et al. (2014) Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy. European Urology, 66(1), pp. 32-39. (doi: 10.1016/j.eururo.2013.08.011) (PMID:24054872) (PMCID:PMC4062940)

Ferrari, Nicola, Mohammed, Zahra M. A., Nixon, Colin, Mason, Susan M., Mallon, Elizabeth, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Morris, Joanna S. ORCID logoORCID: https://orcid.org/0000-0001-5975-2475, Cameron, Ewan R. ORCID logoORCID: https://orcid.org/0000-0001-8311-1491, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Blyth, Karen ORCID logoORCID: https://orcid.org/0000-0002-9304-439X (2014) Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer. PLoS ONE, 9(6), e100759. (doi: 10.1371/journal.pone.0100759) (PMID:24967588) (PMCID:PMC4072705)

McDonald, L. et al. (2014) RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland. Disease Models and Mechanisms, 7(5), pp. 525-534. (doi: 10.1242/dmm.015040)

Gujam, F.J.A., Going, J.J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Mohammed, Z.M.A. and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2014) The role of lymphatic and blood vessel invasion in predicting survival and methods of detection in patients with primary operable breast cancer. Critical Reviews in Oncology/Hematology, 89(2), pp. 231-241. (doi: 10.1016/j.critrevonc.2013.08.014)

McGlynn, L.M. et al. (2014) SIRT2: Tumour suppressor or tumour promoter in operable breast cancer? European Journal of Cancer, 50(2), pp. 290-301. (doi: 10.1016/j.ejca.2013.10.005) (PMID:24183459)

Gujam, F.J.A., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Mohammed, Z.M.A., Going, J.J. and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2014) The relationship between the tumour stroma percentage, clinicopathological characteristics and outcome in patients with operable ductal breast cancer. British Journal of Cancer, 111(1), pp. 157-165. (doi: 10.1038/bjc.2014.279)

2013

Powell, A.G.M.T., Ferguson, J., Al-Mulla, F., Orange, C., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Going, J.J. (2013) The relationship between genetic profiling, clinicopathological factors and survival in patients undergoing surgery for node-negative colorectal cancer: 10-year follow-up. Journal of Cancer Research and Clinical Oncology, 139(12), pp. 2013-2020. (doi: 10.1007/s00432-013-1521-2)

Vijayan, A. et al. (2013) IGFBP-5 enhances epithelial cell adhesion and protects epithelial cells from TGFβ1-induced mesenchymal invasion. International Journal of Biochemistry and Cell Biology, 45(12), pp. 2774-2785. (doi: 10.1016/j.biocel.2013.10.001)

Rutherford, C. et al. (2013) Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1. Cell Death and Disease, 4(11), e927. (doi: 10.1038/cddis.2013.455)

McCall, P., Adams, C.E., Willder, J., Bennett, L., Qayyum, T., Orange, C., Underwood, M. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2013) Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients. International Journal of Molecular Sciences, 14(8), pp. 16656-16671. (doi: 10.3390/ijms140816656) (PMID:23945560) (PMCID:PMC3759930)

Mohammed, Z.M.A., Orange, C., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Mallon, E., Doughty, J.C., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Going, J.J. (2013) Comparison of visual and automated assessment of microvessel density and their impact on outcome in primary operable invasive ductal breast cancer. Human Pathology, 44(8), pp. 1688-1695. (doi: 10.1016/j.humpath.2012.11.023)

Denley, S.M., Jamieson, N.B. ORCID logoORCID: https://orcid.org/0000-0002-9552-4725, McCall, P., Oien, K.C.S. ORCID logoORCID: https://orcid.org/0000-0002-5237-275X, Morton, J.P. ORCID logoORCID: https://orcid.org/0000-0001-5766-9141, Carter, C.R., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McKay, C.J. (2013) Activation of the IL-6R/Jak/Stat pathway is associated with a poor outcome in resected pancreatic ductal adenocarcinoma. Journal of Gastrointestinal Surgery, 17(5), pp. 887-898. (doi: 10.1007/s11605-013-2168-7)

McGlynn, L.M., Tovey, S., Bartlett, J.M.S., Doughty, J., Cooke, T.G. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2013) Interactions between MAP kinase and oestrogen receptor in human breast cancer. European Journal of Cancer, 49(6), pp. 1176-1186. (doi: 10.1016/j.ejca.2012.11.020)

Patel, R. et al. (2013) Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression. Journal of Clinical Investigation, 123(3), pp. 1157-1175. (doi: 10.1172/JCI63672)

Ohotski, J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Elsberger, B., Watson, C., Orange, C., Mallon, E., Pyne, S. and Pyne, N.J. (2013) Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer. International Journal of Cancer, 132(3), pp. 605-616. (doi: 10.1002/ijc.27692)

Willder, J.M. et al. (2013) Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients. British Journal of Cancer, 108(1), pp. 139-148. (doi: 10.1038/bjc.2012.480)

Roxburgh, C.S. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Richards, C.H., MacDonald, A.I., Powell, A.G., McGlynn, L.M., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Shiels, P.G ORCID logoORCID: https://orcid.org/0000-0002-7577-9843 (2013) The in situ local immune response, tumour senescence and proliferation in colorectal cancer. British Journal of Cancer, 109(8), pp. 2207-2216. (doi: 10.1038/bjc.2013.556)

2012

Sebastián, C. et al. (2012) The histone deacetylase SIRT6 is a novel tumor suppressor that controls cancer metabolism. Cell, 151(6), pp. 1185-1199. (doi: 10.1016/j.cell.2012.10.047) (PMID:23217706) (PMCID:PMC3526953)

Mohammed, Z.M.A., Going, J.J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2012) The role of the tumour inflammatory cell infiltrate in predicting recurrence and survival in patients with primary operable breast cancer. Cancer Treatment Reviews, 38(8), pp. 943-955. (doi: 10.1016/j.ctrv.2012.04.011)

Powell, A.G., Wallace, R., McKee, R.F., Anderson, J.H., Going, J.J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 (2012) The relationship between tumour site, clinicopathological characteristics and cancer-specific survival in patients undergoing surgery for colorectal cancer. Colorectal Disease, 14(12), pp. 1493-1499. (doi: 10.1111/j.1463-1318.2012.03048.x)

Mohammed, Z.M.A., Going, J.J., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Orange, C., Mallon, E., Doughty, J.C. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2012) Comparison of visual and automated assessment of HER2 status and their impact on outcome in primary operable invasive ductal breast cancer. Histopathology, 61(4), pp. 675-684. (doi: 10.1111/j.1365-2559.2012.04280.x)

Mohammed, Z.M.A., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Orange, C, Mallon, E., Doughty, J., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Going, J.J. (2012) Breast cancer outcomes by steroid hormone receptor status assessed visually and by computer image analysis. Histopathology, 61(2), pp. 283-292. (doi: 10.1111/j.1365-2559.2012.04244.x)

Ohotski, J., Long, J.S., Orange, C., Elsberger, B., Doughty, J., Pyne, S., Pyne, N.J. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2012) Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer. British Journal of Cancer, 106(8), pp. 1453-1459. (doi: 10.1038/bjc.2012.98)

Powell, A.G.M.T., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 (2012) A move towards individualisation of patient treatment regimens in colorectal cancer. Colorectal Disease, 14(2), pp. 255-256. (doi: 10.1111/j.1463-1318.2011.02818.x)

Pyne, Nigel J., Tonelli, Francesca, Lim, Keng Gat, Long, Jaclyn, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Pyne, Susan (2012) Targeting sphingosine kinase 1 in cancer. Advances in Biological Regulation, 52(1), pp. 31-38. (doi: 10.1016/j.advenzreg.2011.07.001)

Dutta, S., Going, J.J., Crumley, A.B.C, Mohammed, Z., Orange, C., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Fullarton, G.M., Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2012) The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma. British Journal of Cancer, 106(4), pp. 702-710. (doi: 10.1038/bjc.2011.610)

Elsberger, B., Paravasthu, D.M., Tovey, S.M. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2012) Shorter disease-specific survival of ER-positive breast cancer patients with high cytoplasmic Src kinase expression after tamoxifen treatment. Journal of Cancer Research and Clinical Oncology, 138(2), pp. 327-332. (doi: 10.1007/s00432-011-1096-8)

Hu, R. et al. (2012) Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Research, 72(14), pp. 3457-3462. (doi: 10.1158/0008-5472.CAN-11-3892)

McCall, P. et al. (2012) NFκB signalling is upregulated in a subset of castrate-resistant prostate cancer patients and correlates with disease progression. British Journal of Cancer, 107(9), pp. 1554-1563. (doi: 10.1038/bjc.2012.372)

Mohammed, Z.M.A., Going, J.J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Elsberger, B., Doughty, J.C. and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2012) The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast cancer. British Journal of Cancer, 107(5), pp. 864-873. (doi: 10.1038/bjc.2012.347)

Mohammed, Z.M.A., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Elsberger, B., Going, J.J., Orange, C., Mallon, E., Doughty, J.C. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2012) Comparison of visual and automated assessment of Ki-67 proliferative activity and their impact on outcome in primary operable invasive ductal breast cancer. British Journal of Cancer, 106(2), pp. 383-388. (doi: 10.1038/bjc.2011.569)

Powell, A.G.M.T., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 (2012) A move towards individualization of patient treatment regimens in colorectal cancer. Colorectal Disease, 14(2), pp. 255-256. (doi: 10.1111/j.1463-1318.2011.02818.x)

Powell, A.G.M.T., Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905 and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2012) The bodies fight against cancer: is human leucocyte antigen (HLA) class 1 the key? Journal of Cancer Research and Clinical Oncology, 138(5), pp. 723-728. (doi: 10.1007/s00432-012-1192-4)

Pyne, N.J., Tonelli, F., Lim, K.G., Long, J.S., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Pyne, S. (2012) Sphingosine 1-phosphate signalling in cancer. Biochemical Society Transactions, 40(1), pp. 94-100. (doi: 10.1042/BST20110602)

Qayyum, T. et al. (2012) The interrelationships between Src, Cav-1 and RhoGD12 in transitional cell carcinoma of the bladder. British Journal of Cancer, 106(6), pp. 1187-1195. (doi: 10.1038/bjc.2012.52)

Qayyum, T. et al. (2012) Abstracts of the 10th International Kidney Cancer Symposium: The role of Src kinase in renal cell cancer. BJU International, 109(S5), p. 10. (doi: 10.1111/j.1464-410X.2012.11171.x)

Qayyum, T., McArdle, P.A., Going, J.J., Orange, C., Seywright, M., Aitchison, M.A. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2012) Is the presence or absence of tumour necrosis a significant predictor of survival in renal cell cancer? Urologia Internationalis, 88(1), pp. 79-83. (doi: 10.1159/000332430)

Qayyum, T., McArdle, P.A., Lamb, G.W., Going, J.J., Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Oades, G., Aitchison, M.A. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2012) Prospective study of the role of inflammation in renal cancer. Urologia Internationalis, 88(3), pp. 277-281. (doi: 10.1159/000334971)

Qayyum, T. et al. (2012) Expression and prognostic significance of Src family members in renal clear cell carcinoma. British Journal of Cancer, 107(5), pp. 856-863. (doi: 10.1038/bjc.2012.314)

2011

Marsella-Hatziieremia, S., McCall, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2011) Signalling pathways and gene expression profiles in prostate cancer. In: Spiess, P. (ed.) Prostate Cancer: From Bench to Bedside. InTech, pp. 93-114. ISBN 9789533073316 (doi: 10.5772/26971)

Armstrong, K., Ahmad, I. ORCID logoORCID: https://orcid.org/0000-0002-4404-1926, Kalna, G., Tan, SS.S., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Robson, C.N. and Leung, H.Y. ORCID logoORCID: https://orcid.org/0000-0002-3933-3975 (2011) Upregulated FGFR1 expression is associated with the transition of hormone-naive to castrate-resistant prostate cancer. British Journal of Cancer, 105(9), pp. 1362-1369. (doi: 10.1038/bjc.2011.367)

Crumley, A.B.C., Going, J.J., Hilmy, M., Dutta, S., Tannahill, C., McKernan, M., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Stuart, R.C. and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2011) Interrelationships between tumor proliferative activity, leucocyte and macrophage infiltration, systemic inflammatory response, and survival in patients selected for potentially curative resection for gastroesophageal cancer. Annals of Surgical Oncology, 18(9), pp. 2604-2612. (doi: 10.1245/s10434-011-1658-7)

Elsberger, B., Lankston, L., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Underwood, M.A. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2011) Presence of tumoural C-reactive protein correlates with progressive prostate cancer. Prostate Cancer and Prostatic Diseases, 14(2), pp. 122-128. (doi: 10.1038/pcan.2011.5)

Grimsley, S.J.S., Shini, S., Underwood, M.A. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2011) Heregulin expression and prognosis in prostate adenocarcinoma. Urologia Internationalis, 87(3), pp. 363-368. (doi: 10.1159/000328627)

McCall, P,, Catlow, J., McArdle, P.A., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2011) Tumoral C-reactive protein and nuclear factor kappa-B expression are associated with clinical outcome in patients with prostate cancer. Cancer Biomarkers, 10(2), pp. 91-99. (doi: 10.3233/CBM-2012-0236)

Mohammed, Z., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Orange, C., Mallon, E.A., McMillan, D.C. and Going, J.J. (2011) Breast cancer survival stratified by automated versus visual analysis of ER and PR immunohistochemistry. Journal of Pathology, 224(S2), S4. (doi: 10.1002/path.2957)

Mukherjee, R., Mcguinness, D.H. ORCID logoORCID: https://orcid.org/0000-0003-2947-2047, McCall, P., Underwood, M A, Seywright, M, Orange, C and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2011) Upregulation of MAPK pathway is associated with survival in castrate-resistant prostate cancer. British Journal of Cancer, 104(12), pp. 1920-1928. (doi: 10.1038/bjc.2011.163) (PMID:21559022) (PMCID:PMC3111196)

Qayyum, T.Q., McArdle, P.A., Seywright, M., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Aitchison, M.A. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2011) The role of Src in renal cancer. British Journal of Surgery, 98(S2), p. 50. (doi: 10.1002/bjs.7523)

2010

Teo, K., McVitty, C., Mitchell, T., McCall, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Cyclin D1 expression influences overall survival in androgen independent prostate cancer. British Journal of Cancer, 97(S6), p. 26. (doi: 10.1002/bjs.7351)

Watson, C., Long, J.S., Orange, C., Tannahill, C.L., Mallon, E., McGlynn, L.M., Pyne, S., Pyne, N.J. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of tamoxifen resistance in estrogen receptor-positive breast cancer patients. American Journal of Pathology, 177(5), pp. 2205-2215. (doi: 10.2353/ajpath.2010.100220)

Elsberger, B., Fullerton, R., Zino, S., Jordan, F., Mitchell, T.J., Brunton, V.G., Mallon, E.A., Shiels, P.G. ORCID logoORCID: https://orcid.org/0000-0002-7577-9843 and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression. British Journal of Cancer, 103(6), pp. 899-909. (doi: 10.1038/sj.bjc.6605829)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Tannahill, C., Obondo, C., Elsberger, B., Mallon, E., Wilson, C. and Doughty, J. (2010) Expression and activation of Akt and NFkB in breast cancer patients. European Journal of Cancer Supplements, 8(6), pp. 5-6. (doi: 10.1016/j.ejcsup.2010.06.015)

Nam, N.A., Ahmad, I., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Leung, H.Y. and White, R.J. (2010) RNA polymerase III transcription deregulation in cancer: study of Brf1 expression in prostate cancer. European Journal of Cancer Supplements, 8(5), p. 138. (doi: 10.1016/S1359-6349(10)71344-6)

Tan, S., Ahmad, I., Singh, L., Nixon, C., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Leung, H. (2010) Grp78 activity is associated with androgen receptor status and upregulated in Hormone-Refractory prostate cancer. European Journal of Cancer Supplements, 8(5), p. 44. (doi: 10.1016/S1359-6349(10)70975-7)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Src kinase inhibitors: an emerging therapeutic treatment option for prostate cancer. Expert Opinion on Investigational Drugs, 19(5), pp. 605-614. (doi: 10.1517/13543781003789388)

Kirkegaard, T., Witton, C.J., Edwards, J., Nielsen, K.V., Jensen, L.B., Campbell, F.M., Cooke, T.G. and Bartlett, J.M.S. (2010) Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH. Histopathology, 56(2), pp. 203-211. (doi: 10.1111/j.1365-2559.2009.03467.x)

Baneshi, M. R., Warner, P., Anderson, N., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Cooke, T. G. and Bartlett, J. M. S. (2010) Tamoxifen resistance in early breast cancer: statistical modelling of tissue markers to improve risk prediction. British Journal of Cancer, 102(10), pp. 1503-1510. (doi: 10.1038/sj.bjc.6605627)

Darrien, J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McMillan, D. and Horgan, P. (2010) The inter-relationships between tumoural inflammatory infiltrate and expression of C-reactive protein, HIF-1 and NFKb in patients undergoing synchronous colorectal and hepatic resection for Dukes' D colorectal cancer. British Journal of Surgery, 97(S2), p. 65. (doi: 10.1002/bjs.7050)

Elsberger, B., Stewart, B., Tatarov, O. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Is Src a Viable Target for Treating Solid Tumours? Current Cancer Drug Targets, 10(7), pp. 683-694. (doi: 10.2174/156800910793605802)

Elsberger, B., Tan, B.A., Mallon, E.A., Brunton, V.G. and Edwards, J ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Is there an association with phosphorylation and dephosphorylation of Src kinase at tyrosine 530 and breast cancer patient disease-specific survival. British Journal of Cancer, 103(12), pp. 1831-1834. (doi: 10.1038/sj.bjc.6605913)

Long, J. S., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Watson, C., Tovey, S., Mair, K. M., Schiff, R., Natarajan, V., Pyne, N. J. and Pyne, S. (2010) Sphingosine Kinase 1 Induces Tolerance to Human Epidermal Growth Factor Receptor 2 and Prevents Formation of a Migratory Phenotype in Response to Sphingosine 1-Phosphate in Estrogen Receptor-Positive Breast Cancer Cells. Molecular and Cellular Biology, 30(15), pp. 3827-3841. (doi: 10.1128/MCB.01133-09)

Long, J. S., Fujiwara, Y., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Tannahill, C.L., Tigyi, G., Pyne, S. and Pyne, N. J. (2010) Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells. Journal of Biological Chemistry, 285(46), pp. 35957-35966. (doi: 10.1074/jbc.M110.117945)

2009

Elsberger, BC, Tan, BA, Brown, SBF, Mitchell, TJ, Mallon, E, Tovey, S, Brunton, VG, Cooke, TG and Edwards, J (2009) Is Expression or Activation of Src Kinase Associated with Cancer-Specific Survival in ER-, PR- and HER2-Negative Breast Cancer Patients? American Journal of Pathology, 175(4), pp. 1389-1397. (doi: 10.2353/ajpath.2009.090273)

Elsberger, B., Fullerton, R., Tan, A.B. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Survival analysis of most expressed src kinase family members (SKFMs) in human breast carcinoma. Virchows Archiv, 455(Sup. 1), p. 75. (doi: 10.1007/s00428-009-0805-z)

Elsberger, B., Zino, S., Jordan, F., Shiels, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Are Src kinase family members (SKFMS) expressed in human breast cancer? Virchows Archiv, 455(Sup. 1), p. 33. (doi: 10.1007/s00428-009-0805-z)

Stewart, B., Mitchell, T., Leung, H.Y., Robson, C.N. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Membrane c-Src kinase expression is associated with decreased prostate cancer specific survival. BJU International, 103, p. 21.

Guo, Z. et al. (2009) A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Research, 69(6), pp. 2305-2313. (doi: 10.1158/0008-5472.CAN-08-3795)

McGlynn, L.M., Kirkegaard, T., Edwards, J., Tovey, S., Cameron, D., Twelves, C., Bartlett, J.M.S. and Cooke, T.G. (2009) Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients. Clinical Cancer Research, 15(4), pp. 1487-1495. (doi: 10.1158/1078-0432.CCR-07-4967)

Brown, S., Mallon, E., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McGlynn, L., Campbell, F. and Timothy, C. (2009) Is the biology of breast cancer changing? A study of hormone receptor status and grade of breast cancers 1984-1986 and 1996-97. Cancer Research, 69(2), S228. (doi: 10.1158/0008-5472.SABCS-3088)

Brown, S.B.F., Mallon, E.A., Edwards, J., Campbell, F.M., McGlynn, L.M., Elsberger, B. and Cooke, T.G. (2009) Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997. British Journal of Cancer, 100(5), pp. 807-810. (doi: 10.1038/sj.bjc.6604934)

Elsberger, B., Tovey, S., Tan, B., Brown, S., Brunton, V., Mallon, E., Cooke, T. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Phosphorylated c-Src predicts clinical outcome in triple negative breast cancers. Cancer Research, 69(2), S179. (doi: 10.1158/0008-5472.SABCS-2076)

Elsberger, B., Tovey, S., Tan, B., Brown, S., Brunton, V., Mallon, E., Cooke, T. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Role of Src family members in breast cancer-dependent on site of phosphorylation. Cancer Research, 69(2), S178-S179. (doi: 10.1158/0008-5472.SABCS-2074)

Elsberger, B., Zino, S., Fullerton, R., Mitchell, T.J., Shiels, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Are expression levels of Src kinase family members in human breast tissue related to clinical outcome of breast cancer patients? European Journal of Cancer Supplements, 7(2), pp. 93-94. (doi: 10.1016/S1359-6349(09)70316-7)

Elsberger, B., Zino, S., Jordan, F., Fullerton, R., Mitchell, T., Shiels, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Src kinase family members expression in human breast tissue and their association to clinical outcome of breast cancer patients. Cancer Research, 69(24 Sup), S866-S867. (doi: 10.1158/0008-5472.SABCS-09-6130)

McGlynn, L., Curle, J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Shiels, P. (2009) Evaluating the role of sirtuins 5, 6 & 7 in breast cancer. Cancer Research, 69(24 Sup), S657. (doi: 10.1158/0008-5472.SABCS-09-3034)

McGlynn, L., Reilly, J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Shiels, P. (2009) Role of SIRT2, SIRT3 and SIRT4 in breast cancer. Cancer Research, 69(24 Sup), S656-S657. (doi: 10.1158/0008-5472.SABCS-09-3032)

Tannahill, C., Obondo, C., Al-Murri, A., Doughty, J., Lannigan, A., Wilson, C., McMillan, D. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) The relationship between tumour NF-kB expression, hormone status, and clinicopathological factors in primary invasive breast cancer. Cancer Research, 69(2), S263. (doi: 10.1158/0008-5472.SABCS-4038)

Tannahill, C., Obondo, C., Tovey, S., Orange, C., Doughty, J., Wilson, C., Cooke, T., McMillan, D. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) The relationship between tumour NF-kB expression, hormone status and survival in primary invasive breast cancer. Cancer Research, 69(2), S264. (doi: 10.1158/0008-5472.SABCS-4041)

Tatarov, O., Mitchell, T.J., Seywright, M., Leung, H.Y. ORCID logoORCID: https://orcid.org/0000-0002-3933-3975, Brunton, V.G. and Edwards, J. (2009) Src family kinase activity is up-regulated in hormone refractory prostate cancer. Clinical Cancer Research, 15(10), pp. 3540-3549. (doi: 10.1158/1078-0432.CCR-08-1857)

Tovey, S., Marla, S., Brown, S., Burton, P., Canney, P., Stallard, S., Mallon, E., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Cooke, T. (2009) Poor survival outcomes in HER2 positive breast cancer patients with low grade, node negative tumours. Implications for trastuzumab therapy? Cancer Research, 69(2), S98-0. (doi: 10.1158/0008-5472.SABCS-702)

Tovey, S., Tan, B., Campbell, J., Elsberger, B., Brunton, V., Mallon, E., Cooke, T. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Activated c-Src (Y215) kinase expression predicts for early relapse on tamoxifen in human breast cancer. Cancer Research, 69(2), S212-0. (doi: 10.1158/0008-5472.SABCS-3025)

Tovey, S.M., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Brown, S., Mallon, E. and Doughty, J. (2009) Poor survival outcomes in elderly HER2 positive breast cancer patients. Cancer Research, 69(24 Sup), S595. (doi: 10.1158/0008-5472.SABCS-09-2010)

Tovey, S.M., Brown, S.B., Doughty, J.C., Mallon, E.A., Cooke, T.G. and Edwards, J. (2009) Poor survival outcomes in HER2 positive breast cancer patients with low grade, node negative tumours. British Journal of Cancer, 100(5), pp. 680-683. (doi: 10.1038/sj.bjc.6604940)

Watson, C., Kipgen, D., Orange, C., Tovey, S., Cooke, T., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Leung, H. (2009) Role of extracellular signal-regulated kinase 5 (ERK5) in human breast cancer. Cancer Research, 69(2), S264. (doi: 10.1158/0008-5472.SABCS-4042)

2008

Tovey, S., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Brown, S., Mallon, E. and Cooke, T. (2008) Poor survival outcomes in HER2 positive breast cancer patients with low grade, node negative tumours. European Journal of Cancer Supplements, 6(9), pp. 105-106. (doi: 10.1016/S1359-6349(08)71578-7)

Kirkegaard, T., Naresh, A., Sabine, V.S., Tovey, S.M., Edwards, J., Dunne, B., Cooke, T.G., Jones, F.E. and Bartlett, J.M.S. (2008) Expression of tumor necrosis factor [alpha] converting enzyme in endocrine cancers. American Journal of Clinical Pathology, 129, pp. 735-743. (doi: 10.1309/N6YB6YDVF58YCNHN)

Lamb, G.W., McArdle, P.A., Ramsey, S., McNichol, A.M., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Aitchison, M. and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2008) The relationship between the local and systemic inflammatory responses and survival in patients undergoing resection for localized renal cancer. BJU International, 102(6), pp. 756-761. (doi: 10.1111/j.1464-410X.2008.07666.x)

Campbell, E.J., McDuff, E., Tatarov, O., Tovey, S., Brunton, V.G., Cooke, T.G. and Edwards, J. (2008) Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer. British Journal of Cancer, 99(11), pp. 1769-1774. (doi: 10.1038/sj.bjc.6604768)

McCall, P., Gemmell, L.K., Mukherjee, R., Bartlett, J.M.S. and Edwards, J. (2008) Phosphorylation of the androgen receptor is associated with reduced survival in hormonerefractory prostate cancer patients. British Journal of Cancer, 98(6), pp. 1094-1101. (doi: 10.1038/sj.bjc.6604152)

McCall, P., Witton, C.J., Grimsley, S., Nielsen, K.V. and Edwards, J. (2008) Is PTEN loss associated with clinical outcome measures in human prostate cancer? British Journal of Cancer, 99(8), pp. 1296-1301. (doi: 10.1038/sj.bjc.6604680)

McCracken, S.R.C., Ramsay, A., Heer, R., Mathers, M.E., Jenkins, B.L., Edwards, J., Robson, C.N., Marquez, R., Cohen, P. and Leung, H.Y. (2008) Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer. Oncogene, 27(21), pp. 2978-2988. (doi: 10.1038/sj.onc.1210963)

Traynor, P., McGlynn, L.M., Mukherjee, R., Grimsley, S.L.S., Bartlett, J.M.S. and Edwards, J. (2008) An increase in N-Ras expression is associated with development of hormone refractory prostate cancer in a subset of patients. Disease Markers, 24(3), pp. 157-165.

2007

Edwards, J. and Leung, H.Y. (2007) Editorial comment on: increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells. European Urology, 52(6), pp. 1680-1681. (doi: 10.1016/j.eururo.2007.01.098)

Tam, L., McGlynn, L.M., Traynor, P., Mukherjee, R., Bartlett, J.M.S. and Edwards, J. (2007) Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer. British Journal of Cancer, 97(3), pp. 378-383. (doi: 10.1038/sj.bjc.6603871)

Tam, L., McGlynn, L.M., Traynor, P., Mukherjee, R., Bartlett, J.M.S. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2007) Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer. British Journal of Cancer, 97(3), pp. 378-383. (doi: 10.1038/sj.bjc.6603871)

Teo, K., Gemmell, L., Mukherjee, R., Traynor, P. and Edwards, J. (2007) Bad expression influences time to androgen escape in prostate cancer. BJU International, 100(3), pp. 691-696. (doi: 10.1111/j.1464-410X.2007.07001.x)

2006

Edwards, J., Traynor, P., Munro, A., Pirrett, C.F., Dunne, B. and Bartlett, J.M.S. (2006) The role of HER1-HER4 and EGFRvIII in hormone-refractory prostate cancer. Clinical Cancer Research, 12(1), pp. 123-130. (doi: 10.1158/1078-0432.CCR-05-1445)

Kirkegaard, T., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Tovey, S., McGlynn, L.M., Krishna, S.N., Mukherjee, R., Tam, L., Munro, A.F., Dunne, B. and Bartlett, J.M. (2006) Observer variation in immunohistochemical analysis of protein expression, time for a change? Histopathology, 48(7), pp. 787-794. (doi: 10.1111/j.1365-2559.2006.02412.x)

2005

Bartlett, J.M., Brawley, D., Grigor, K.M., Munro, A.F., Dunne, B. and Edwards, J. (2005) Type I receptor tyrosine kinases are associated with hormone escape in prostate cancer. Journal of Pathology, 205(4), pp. 522-529. (doi: 10.1002/path.1735)

Edwards, J. and Bartlett, J.M.S. (2005) The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: modifications to the androgen receptor. BJU International, 95(9), pp. 1320-1326. (doi: 10.1111/j.1464-410X.2005.05526.x)

Edwards, J. and Bartlett, J.M.S. (2005) The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: androgen-receptor cofactors and bypass pathways. BJU International, 95(9), pp. 1327-1335. (doi: 10.1111/j.1464-410X.2005.05527.x)

Mukherjee, R., Bartlett, J.M.S., Krishna, N.S., Underwood, M.A. and Edwards, J. (2005) Raf-1 expression may influence progression to androgen insensitive prostate cancer. Prostate, 64(1), pp. 101-107. (doi: 10.1002/pros.20211)

Mukherjee, R., Edwards, J., Underwood, M.A. and Bartlett, J.M.S. (2005) The relationship between angiogenesis and cyclooxygenase-2 expression in prostate cancer. BJU International, 96(1), pp. 62-66. (doi: 10.1111/j.1464-410X.2005.05568.x)

2004

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Mukherjee, R., Munro, A.F., Wells, A.C., Almushatat, A. and Bartlett, J.M.S. (2004) HER2 and COX2 expression in human prostate cancer. European Journal of Cancer, 40(1), pp. 50-55. (doi: 10.1016/j.ejca.2003.08.010)

2003

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Krishna, N.S., Grigor, K.M. and Bartlett, J.M.S. (2003) Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. British Journal of Cancer, 89(3), pp. 552-556. (doi: 10.1038/sj.bjc.6601127)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Krishnan, S., Witton, C.J. and Bartlett, J.M.S. (2003) Gene amplifications associated with the development of hormone- resistant prostate cancer. Clinical Cancer Research, 9(14), pp. 5271-5281.

2002

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Duncan, P., Going, J.J., Watters, A.D., Grigor, K.M. and Bartlett, J.M.S. (2002) Identification of loci associated with putative recurrence genes in transitional cell carcinoma of the urinary bladder. Journal of Pathology, 196(4), pp. 380-385. (doi: 10.1002/path.1052)

Brown, R.S.D., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Bartlett, J.M.S., Jones, C. and Dogan, A. (2002) Routine acid decalcification of bone marrow samples can preserve DNA for FISH and CGH studies in metastatic prostate cancer. Journal of Histochemistry and Cytochemistry, 50(1), pp. 113-115.

Brown, R.S.D., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dogan, A., Payne, H., Harland, S.J., Bartlett, J.M.S. and Masters, J.R.W. (2002) Amplification of the androgen receptor gene in bone metastases from hormone-refractory prostate cancer. Journal of Pathology, 198(2), pp. 237-244. (doi: 10.1002/path.1206)

Mir, K., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Paterson, P.J. ORCID logoORCID: https://orcid.org/0000-0002-9918-537X, Hehir, M., Underwood, M.A. and Bartlett, J.M.S. (2002) The CAG trinucleotide repeat length in the androgen receptor does not predict the early onset of prostate cancer. BJU International, 90(6), pp. 573-578. (doi: 10.1046/j.1464-410X.2002.02981.x)

2001

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Duncan, P., Going, J.J., Grigor, K.M., Watters, A.D. and Bartlett, J.M.S. (2001) Loss of heterozygosity on chromosomes 11 and 17 are markers of recurrence in TCC of the bladder. British Journal of Cancer, 85(12), pp. 1894-1899. (doi: 10.1054/bjoc.2001.2159)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Krishna, N.S., Mukherjee, R., Watters, A.D., Underwood, M.A. and Bartlett, J.M.S. (2001) Amplification of the androgen receptor may not explain the development of androgen-independent prostate cancer. BJU International, 88(6), pp. 633-637. (doi: 10.1046/j.1464-410X.2001.02350.x)

1999

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Bartlett, J.M.S. (1999) Induction of apoptosis and inhibition of cellular proliferation as a dual approach to treatment of ovarian cancer. International Journal of Oncology, 15(3), pp. 583-588.

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Articles

Woraharn, W. et al. (2025) Investigation of three alternative histopathological scoring methods at the invasive tumour front in colorectal cancer. Journal of Pathology: Clinical Research, 11(3), e70031. (doi: 10.1002/2056-4538.70031)

Thompson, Joshua J., MacLeod, Nicholas, Will, Sarah, O'Rourke, Fraser, McGovern, Josh, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dolan, Ross D. ORCID logoORCID: https://orcid.org/0000-0002-5272-5906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2025) The prognostic value of a laboratory cachexia score (LCAS) defined by LDH, CRP and albumin in patients with advanced lung cancer. BMC Cancer, 25, 543. (doi: 10.1186/s12885-025-13426-3) (PMID:40133911) (PMCID:PMC11938618)

Dolan, R. D. et al. (2025) The relationship between tumour necrosis, systemic inflammation, body composition and survival in patients with colon cancer. BJC Reports, 3(1), 7. (doi: 10.1038/s44276-024-00119-w) (PMID:39910331)

Mathews, C. et al. (2025) Retrospective cohort study: scope for improvement - barriers to post-polypectomy surveillance in the integrated technologies for improved polyp surveillance cohort. Alimentary Pharmacology and Therapeutics, (doi: 10.1111/apt.18514) (Early Online Publication)

Pennel, K. et al. (2024) IL6 and IL6R as prognostic biomarkers in colorectal cancer. Biomolecules, 14(12), 1629. (doi: 10.3390/biom14121629)

Shamis, S. A.K. et al. (2024) Elucidation of dysregulated pathways associated with hypoxia in oestrogen receptor-negative breast cancer. Cancer Medicine, 13(23), e70274. (doi: 10.1002/cam4.70274) (PMID:39660488) (PMCID:PMC11632397)

Galbraith, N. J. et al. (2024) TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer. Translational Oncology, 48, 102064. (doi: 10.1016/j.tranon.2024.102064) (PMID:39068768)

Knight, Katrina, Bigley, Christopher, Pennel, Kathryn, Hay, Jennifer, Maka, Noori, McMillan, Donald ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Park, James ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) The Glasgow Microenvironment Score: an exemplar of contemporary biomarker evolution in colorectal cancer. Journal of Pathology: Clinical Research, 10, e12385. (doi: 10.1002/2056-4538.12385) (PMID:38853386)

Thompson, Joshua, McGovern, Josh, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dolan, Ross D. ORCID logoORCID: https://orcid.org/0000-0002-5272-5906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2024) The relationship between LDH and GLIM criteria for cancer cachexia: systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 199, 104378. (doi: 10.1016/j.critrevonc.2024.104378) (PMID:38754770)

McKenzie, Molly, Lian, Guang-Yu, Pennel, Kathryn A.F., Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Jamieson, Nigel B. ORCID logoORCID: https://orcid.org/0000-0002-9552-4725 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) NFκB signalling in colorectal cancer: examining the central dogma of IKKα and IKKβ signalling. Heliyon, 10(12), e32904. (doi: 10.1016/j.heliyon.2024.e32904) (PMID:38975078) (PMCID:PMC11226910)

Hatthakarnkul, P. et al. (2024) Histopathological tumour microenvironment score independently predicts outcome in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 10(3), e12374. (doi: 10.1002/2056-4538.12374) (PMID:38650367) (PMCID:PMC11035902)

Pennel, Kathryn, Dutton, Louise ORCID logoORCID: https://orcid.org/0000-0002-9336-7826, Melissourgou-Syka, Lydia ORCID logoORCID: https://orcid.org/0000-0002-0926-2328, Roxburgh, Campbell ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Birch, Joanna ORCID logoORCID: https://orcid.org/0000-0001-9522-8435 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) Novel radiation and targeted therapy combinations for improving rectal cancer outcomes. Expert Reviews in Molecular Medicine, 26, e14. (doi: 10.1017/erm.2024.15) (PMID:38623751) (PMCID:PMC11140547)

Domingo, E. et al. (2024) Prognostic and predictive value of Immunoscore in stage III colorectal cancer: pooled analysis of 2,608 cases from the SCOT and IDEA-HORG studies. Journal of Clinical Oncology, (doi: 10.1200/JCO.23.01648) (PMID:38484206) (Early Online Publication)

Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)

Frei, A. L. et al. (2024) Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II–III colorectal cancer from the SCOT and QUASAR 2 trials: A retrospective analysis. Lancet Oncology, 25(2), pp. 198-211. (doi: 10.1016/S1470-2045(23)00560-0) (PMID:38301689)

Hillson, Lily Victoria Sarah, McCulloch, Ashley Kathryn, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dunne, Philip David, O'Cathail, Sean Michael ORCID logoORCID: https://orcid.org/0000-0001-5574-9199 and Roxburgh, Campbell Stuart ORCID logoORCID: https://orcid.org/0000-0002-2649-6695 (2024) Radiation-induced changes in gene expression in rectal cancer specimens. Clinical and Translational Oncology, (doi: 10.1007/s12094-023-03361-9) (PMID:38243085) (Early Online Publication)

Brouwer, N.P.M. et al. (2024) The complexity of shapes: how the circularity of tumor nodules impacts prognosis in colorectal cancer. Modern Pathology, 37(1), 100376. (doi: 10.1016/j.modpat.2023.100376) (PMID:37926423)

Shamis, Suad Ahmad Khalifa, Savioli, Francesca, Ammar, Aula ORCID logoORCID: https://orcid.org/0000-0002-0375-062X, Al-Badran, Sara S.F., Hatthakarnkul, Phimmada, Leslie, Holly ORCID logoORCID: https://orcid.org/0000-0001-8898-3600, Mallon, Elizabeth, Jamieson, Nigel B. ORCID logoORCID: https://orcid.org/0000-0002-9552-4725, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2024) Spatial transcriptomic analysis of tumour with high and low CAIX expression in TNBC tissue samples using GeoMx™ RNA assay. Histology and Histopathology: Cellular and Molecular Biology, 39, pp. 177-200. (doi: 10.14670/HH-18-655) (PMID:37681672)

Beach, C. et al. (2023) Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1. Journal of Clinical Investigation, 133(23), e168277. (doi: 10.1172/JCI168277) (PMID:37824211) (PMCID:PMC10688992)

Frei, A. L. et al. (2023) Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets. Journal of Pathology: Clinical Research, 9(6), pp. 449-463. (doi: 10.1002/cjp2.342) (PMID:37697694) (PMCID:PMC10556275)

Suzuki, T. et al. (2023) β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer. Cancer Immunology Research, 11(8), pp. 1137-1155. (doi: 10.1158/2326-6066.CIR-22-0644) (PMID:37309673) (PMCID:PMC10398359)

Vande Voorde, J. et al. (2023) Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target. Nature Metabolism, 5(8), pp. 1303-1318. (doi: 10.1038/s42255-023-00857-0) (PMID:37580540) (PMCID:PMC10447251)

Hatthakarnkul, P. et al. (2023) Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer. Journal of Cancer, 14(10), pp. 1837-1847. (doi: 10.7150/jca.83910) (PMID:37476187) (PMCID:PMC10355195)

Johnstone, Mark S., Stoops, Reiss, Lynch, Gerard, Hay, Jennifer, Jawny, Jakub, Sloan, William, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McSorley, Stephen T. ORCID logoORCID: https://orcid.org/0000-0002-5459-8445 (2023) Risk stratification for the detection of metachronous polyps after bowel screening polypectomy: clinical outcomes from the Integrated Technologies for Improved Polyp Surveillance (INCISE) study cohort. BJS Open, 7(3), zrad034. (doi: 10.1093/bjsopen/zrad034) (PMID:37158435) (PMCID:PMC10167706)

Pennel, Kathryn, Morrow, Elizabeth, Hatthakarnkul, Phimmada, Leslie, Holly ORCID logoORCID: https://orcid.org/0000-0001-8898-3600, Mallon, Elizabeth, Andersen, Ditte, Jamieson, Nigel ORCID logoORCID: https://orcid.org/0000-0002-9552-4725, McMillan, Donald ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Roseweir, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6158-1564 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2023) High expression of STAT3 within the tumour-associated stroma predicts poor outcome in breast cancer patients. Cancer Medicine, 12(12), pp. 13225-13240. (doi: 10.1002/cam4.6014) (PMID:37199043) (PMCID:PMC10315752)

Shamis, Suad A.K., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2023) The relationship between carbonic anhydrase IX (CAIX) and patient survival in breast cancer: systematic review and meta-analysis. Diagnostic Pathology, 18, 46. (doi: 10.1186/s13000-023-01325-9) (PMID:37061698) (PMCID:PMC10105416)

Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)

Numprasit, Warapan, Yangngam, Supaporn, Prasopsiri, Jaturawitt, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Thuwajit, Chanitra (2023) Carbonic anhydrase IX-related tumoral hypoxia predicts worse prognosis in breast cancer: a systematic review and meta-analysis. Frontiers in Medicine, 10, 1087270. (doi: 10.3389/fmed.2023.1087270) (PMID:37007798) (PMCID:PMC10063856)

Alexander, P.G., van Wyk, H.C. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, Pennel, K.A.F., Hay, J., McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, Roxburgh, C.S.D. ORCID logoORCID: https://orcid.org/0000-0002-2649-6695, Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Park, J.H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037 (2023) The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer. British Journal of Cancer, 128(4), pp. 556-567. (doi: 10.1038/s41416-022-02069-x) (PMID:36476660) (PMCID:PMC9938140)

Tandon, Vasudha, Moreno, Rita, Allmeroth, Kira, Quinn, Jean ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Wiley, Sandra E., Nicely, Lynden G., Denzel, Martin S., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, de la Vega, Laureano and Banerjee, Sourav (2023) Dual inhibition of HSF1 and DYRK2 impedes cancer progression. Bioscience Reports, 34(1), BSR2022210. (doi: 10.1042/BSR20222102) (PMID:36622366) (PMCID:PMC9894012)

Patel, Meera, McAllister, Milly, Nagaraju, Raghavendar, Al Badran, Sara Samir Foad, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McBain, Andrew J., Barriuso, Jorge and Aziz, Omer (2022) The intestinal microbiota in colorectal cancer metastasis - Passive observer or key player? Critical Reviews in Oncology/Hematology, 180, 103856. (doi: 10.1016/j.critrevonc.2022.103856) (PMID:36257533)

Savioli, Francesca, Morrow, Elizabeth S., Dolan, Ross D. ORCID logoORCID: https://orcid.org/0000-0002-5272-5906, Romics, Laszlo, Lannigan, Alison, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2022) Prognostic role of preoperative circulating systemic inflammatory response markers in primary breast cancer: meta-analysis. British Journal of Surgery, 109(12), pp. 1206-1215. (doi: 10.1093/bjs/znac319) (PMID:36130112)

Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)

Alexander, P. G. et al. (2022) The relationship between the Glasgow Microenvironment Score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer. Human Pathology, 127, pp. 1-11. (doi: 10.1016/j.humpath.2022.05.012) (PMID:35623467)

Yangngam, Supaporn, Prasopsiri, Jaturawitt, Hatthakarnkul, Phimmada, Thongchot, Suyanee, Thuwajit, Peti, Yenchitsomanus, Pa-thai, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Thuwajit, Chanitra (2022) Cellular localization of nucleolin determines the prognosis in cancers: a meta-analysis. Journal of Molecular Medicine, 100(8), pp. 1145-1157. (doi: 10.1007/s00109-022-02228-w) (PMID:35861882) (PMCID:PMC9329415)

Shamis, Suad A.K., Quinn, Jean ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Mallon, Elizabeth E.A., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2022) The relationship between the tumor cell expression of hypoxic markers and survival in patients with ER-positive invasive ductal breast cancer. Journal of Histochemistry and Cytochemistry, 70(7), pp. 479-494. (doi: 10.1369/00221554221110280) (PMID:35792080)

Patel, M. et al. (2022) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. British Journal of Cancer, 126(12), pp. 1704-1714. (doi: 10.1038/s41416-022-01729-2) (PMID:35173303) (PMCID:PMC9174220)

Hatthakarnkul, Phimmada, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Ammar, Aula ORCID logoORCID: https://orcid.org/0000-0002-0375-062X, Lynch, Gerard, Van Wyk, Hester ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Thuwajit, Chanitra and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2022) Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer. Clinical Science, 136(8), pp. 521-535. (doi: 10.1042/CS20210886) (PMID:35445707)

Blomme, A. et al. (2022) THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer. EMBO Molecular Medicine, 14(3), e14764. (doi: 10.15252/emmm.202114764) (PMID:35014179) (PMCID:PMC8899912)

Lampis, A. et al. (2021) MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer. Cell Death and Differentiation, 28, pp. 2970-2982. (doi: 10.1038/s41418-021-00820-0) (PMID:34226680) (PMCID:PMC8481293)

Hanna, C. R. et al. (2021) Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT). Radiation Oncology, 16, 163. (doi: 10.1186/s13014-021-01888-1) (PMID:34446053)

Johnstone, Mark S., Lynch, Gerard, Park, James ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, McSorley, Stephen ORCID logoORCID: https://orcid.org/0000-0002-5459-8445 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) Novel methods of risk stratifying patients for metachronous, pre-malignant colorectal polyps: a systematic review. Critical Reviews in Oncology/Haematology, 164, 103421. (doi: 10.1016/j.critrevonc.2021.103421) (PMID:34246774)

Mansouri, David ORCID logoORCID: https://orcid.org/0000-0002-9157-6085, McSorley, Stephen T. ORCID logoORCID: https://orcid.org/0000-0002-5459-8445, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037, Orange, Clare, Horgan, Paul G. ORCID logoORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) The inflammatory microenvironment in screen-detected premaligant adenomatous polyps: early results from the integrated technologies for improved polyp surveillance (INCISE) project. European Journal of Gastroenterology and Hepatology, 33(7), pp. 983-989. (doi: 10.1097/MEG.0000000000002202) (PMID:34034277)

Matly, Amna, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Park, James H. ORCID logoORCID: https://orcid.org/0000-0002-6551-2037 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) The relationship between β-catenin and patient survival in colorectal cancer systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 163, 103337. (doi: 10.1016/j.critrevonc.2021.103337) (PMID:33992802)

Knight, J. R.P. et al. (2021) MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression. Cancer Discovery, 11(5), pp. 1228-1247. (doi: 10.1158/2159-8290.CD-20-0652) (PMID:33328217)

Moreno, Rita, Banerjee, Sourav, Jackson, Angus W, Quinn, Jean ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Baillie, Gregg, Dixon, Jack E, Dinkova-Kostova, Albena T, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and de la Vega, Laureano (2021) The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress. Cell Death and Differentiation, 28(5), pp. 1563-1578. (doi: 10.1038/s41418-020-00686-8) (PMID:33268814)

Al-Badran, S. S.F. et al. (2021) Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 7(2), pp. 121-134. (doi: 10.1002/cjp2.193) (PMID:33338327)

Shamis, Suad Ahmad Khalifa, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) The relationship between Hypoxia-inducible factor 1α (HIF-1α) and patient survival in breast cancer: systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 159, 103231. (doi: 10.1016/j.critrevonc.2021.103231) (PMID:33482350)

Hatthakarnkul, Phimmada, Quinn, Jean A. ORCID logoORCID: https://orcid.org/0000-0002-8267-0993, Matly, Amna Ahmed Mohemmd, Ammar, Aula ORCID logoORCID: https://orcid.org/0000-0002-0375-062X, Van Wyk, Hester C. ORCID logoORCID: https://orcid.org/0000-0002-4978-5000, McMillan, Donald C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2021) Systematic review of tumour budding and association with common mutations in patients with colorectal cancer. Critical Reviews in Oncology/Hematology, 167, 103490. (doi: 10.1016/j.critrevonc.2021.103490) (PMID:34619332)

McAllister, Milly J., McCall, Pamela, Dickson, Ashley, Underwood, Mark A., Andersen, Ditte, Holmes, Elizabeth, Market, Elke, Leung, Hing Y. ORCID logoORCID: https://orcid.org/0000-0002-3933-3975 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2020) Androgen receptor phosphorylation at serine 81 and serine 213 in castrate-resistant prostate cancer. Prostate Cancer and Prostatic Diseases, 23(4), pp. 596-606. (doi: 10.1038/s41391-020-0235-1) (PMID:32358577)

McAllister, Milly, Constancio, Vera, Patek, Samantha, Gan, Hao, Bailey, Peter ORCID logoORCID: https://orcid.org/0000-0002-0857-2041, Wheadon, Helen ORCID logoORCID: https://orcid.org/0000-0001-9902-3170, Underwood, Mark, Leung, Hing ORCID logoORCID: https://orcid.org/0000-0002-3933-3975 and Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2020) Inflammatory infiltration is associated with AR expression and poor prognosis in hormone naïve prostate cancer. Prostate, 80(15), pp. 1353-1364. (doi: 10.1002/pros.24064) (PMID:32846021)

Savioli, F., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McMillan, D. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334, Stallard, S., Doughty, J. and Romics, L. (2020) The effect of postoperative complications on survival and recurrence after surgery for breast cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 155, 103075. (doi: 10.1016/j.critrevonc.2020.103075) (PMID:32987333)

Suzuki, Toshiyasu, Hayman, Liam, Kilbey, Anna, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Coffelt, Seth B. ORCID logoORCID: https://orcid.org/0000-0003-2257-2862 (2020) Gut γδ T cells as guardians, disruptors and instigators of cancer. Immunological Reviews, 298(1), pp. 198-217. (doi: 10.1111/imr.12916) (PMID:32840001)

Alexander, P.G. et al. (2020) The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British Journal of Cancer, 124, pp. 786-796. (doi: 10.1038/s41416-020-01168-x) (PMID:33223535)

Montes, M. et al. (2020) Determining the prognostic significance of IKKα in prostate cancer. Prostate, 80(14), pp. 1188-1202. (doi: 10.1002/pros.24045) (PMID:33258506)

Roseweir, A. K. et al. (2020) Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. Journal of Pathology: Clinical Research, 6(4), pp. 283-296. (doi: 10.1002/cjp2.171) (PMID:32401426) (PMCID:PMC7578335)

Torrente, L. et al. (2020) High NRF2 levels correlate with poor prognosis in colorectal cancer patients and with sensitivity to the kinase inhibitor AT9283 in vitro. Biomolecules, 10(10), 1365. (doi: 10.3390/biom10101365) (PMID:32992842) (PMCID:PMC7600603)

Rooney, N. et al. (2020) RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome. Cancer Research, 80(11), pp. 2325-2339. (doi: 10.1158/0008-5472.CAN-19-3870) (PMID:32156779)

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Tan, S., Ahmad, I., Singh, L., Nixon, C., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Leung, H. (2010) Grp78 activity is associated with androgen receptor status and upregulated in Hormone-Refractory prostate cancer. European Journal of Cancer Supplements, 8(5), p. 44. (doi: 10.1016/S1359-6349(10)70975-7)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Src kinase inhibitors: an emerging therapeutic treatment option for prostate cancer. Expert Opinion on Investigational Drugs, 19(5), pp. 605-614. (doi: 10.1517/13543781003789388)

Kirkegaard, T., Witton, C.J., Edwards, J., Nielsen, K.V., Jensen, L.B., Campbell, F.M., Cooke, T.G. and Bartlett, J.M.S. (2010) Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH. Histopathology, 56(2), pp. 203-211. (doi: 10.1111/j.1365-2559.2009.03467.x)

Baneshi, M. R., Warner, P., Anderson, N., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Cooke, T. G. and Bartlett, J. M. S. (2010) Tamoxifen resistance in early breast cancer: statistical modelling of tissue markers to improve risk prediction. British Journal of Cancer, 102(10), pp. 1503-1510. (doi: 10.1038/sj.bjc.6605627)

Darrien, J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McMillan, D. and Horgan, P. (2010) The inter-relationships between tumoural inflammatory infiltrate and expression of C-reactive protein, HIF-1 and NFKb in patients undergoing synchronous colorectal and hepatic resection for Dukes' D colorectal cancer. British Journal of Surgery, 97(S2), p. 65. (doi: 10.1002/bjs.7050)

Elsberger, B., Stewart, B., Tatarov, O. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Is Src a Viable Target for Treating Solid Tumours? Current Cancer Drug Targets, 10(7), pp. 683-694. (doi: 10.2174/156800910793605802)

Elsberger, B., Tan, B.A., Mallon, E.A., Brunton, V.G. and Edwards, J ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2010) Is there an association with phosphorylation and dephosphorylation of Src kinase at tyrosine 530 and breast cancer patient disease-specific survival. British Journal of Cancer, 103(12), pp. 1831-1834. (doi: 10.1038/sj.bjc.6605913)

Long, J. S., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Watson, C., Tovey, S., Mair, K. M., Schiff, R., Natarajan, V., Pyne, N. J. and Pyne, S. (2010) Sphingosine Kinase 1 Induces Tolerance to Human Epidermal Growth Factor Receptor 2 and Prevents Formation of a Migratory Phenotype in Response to Sphingosine 1-Phosphate in Estrogen Receptor-Positive Breast Cancer Cells. Molecular and Cellular Biology, 30(15), pp. 3827-3841. (doi: 10.1128/MCB.01133-09)

Long, J. S., Fujiwara, Y., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Tannahill, C.L., Tigyi, G., Pyne, S. and Pyne, N. J. (2010) Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells. Journal of Biological Chemistry, 285(46), pp. 35957-35966. (doi: 10.1074/jbc.M110.117945)

Elsberger, BC, Tan, BA, Brown, SBF, Mitchell, TJ, Mallon, E, Tovey, S, Brunton, VG, Cooke, TG and Edwards, J (2009) Is Expression or Activation of Src Kinase Associated with Cancer-Specific Survival in ER-, PR- and HER2-Negative Breast Cancer Patients? American Journal of Pathology, 175(4), pp. 1389-1397. (doi: 10.2353/ajpath.2009.090273)

Elsberger, B., Fullerton, R., Tan, A.B. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Survival analysis of most expressed src kinase family members (SKFMs) in human breast carcinoma. Virchows Archiv, 455(Sup. 1), p. 75. (doi: 10.1007/s00428-009-0805-z)

Elsberger, B., Zino, S., Jordan, F., Shiels, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Are Src kinase family members (SKFMS) expressed in human breast cancer? Virchows Archiv, 455(Sup. 1), p. 33. (doi: 10.1007/s00428-009-0805-z)

Stewart, B., Mitchell, T., Leung, H.Y., Robson, C.N. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Membrane c-Src kinase expression is associated with decreased prostate cancer specific survival. BJU International, 103, p. 21.

Guo, Z. et al. (2009) A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Research, 69(6), pp. 2305-2313. (doi: 10.1158/0008-5472.CAN-08-3795)

McGlynn, L.M., Kirkegaard, T., Edwards, J., Tovey, S., Cameron, D., Twelves, C., Bartlett, J.M.S. and Cooke, T.G. (2009) Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients. Clinical Cancer Research, 15(4), pp. 1487-1495. (doi: 10.1158/1078-0432.CCR-07-4967)

Brown, S., Mallon, E., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, McGlynn, L., Campbell, F. and Timothy, C. (2009) Is the biology of breast cancer changing? A study of hormone receptor status and grade of breast cancers 1984-1986 and 1996-97. Cancer Research, 69(2), S228. (doi: 10.1158/0008-5472.SABCS-3088)

Brown, S.B.F., Mallon, E.A., Edwards, J., Campbell, F.M., McGlynn, L.M., Elsberger, B. and Cooke, T.G. (2009) Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997. British Journal of Cancer, 100(5), pp. 807-810. (doi: 10.1038/sj.bjc.6604934)

Elsberger, B., Tovey, S., Tan, B., Brown, S., Brunton, V., Mallon, E., Cooke, T. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Phosphorylated c-Src predicts clinical outcome in triple negative breast cancers. Cancer Research, 69(2), S179. (doi: 10.1158/0008-5472.SABCS-2076)

Elsberger, B., Tovey, S., Tan, B., Brown, S., Brunton, V., Mallon, E., Cooke, T. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Role of Src family members in breast cancer-dependent on site of phosphorylation. Cancer Research, 69(2), S178-S179. (doi: 10.1158/0008-5472.SABCS-2074)

Elsberger, B., Zino, S., Fullerton, R., Mitchell, T.J., Shiels, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Are expression levels of Src kinase family members in human breast tissue related to clinical outcome of breast cancer patients? European Journal of Cancer Supplements, 7(2), pp. 93-94. (doi: 10.1016/S1359-6349(09)70316-7)

Elsberger, B., Zino, S., Jordan, F., Fullerton, R., Mitchell, T., Shiels, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Src kinase family members expression in human breast tissue and their association to clinical outcome of breast cancer patients. Cancer Research, 69(24 Sup), S866-S867. (doi: 10.1158/0008-5472.SABCS-09-6130)

McGlynn, L., Curle, J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Shiels, P. (2009) Evaluating the role of sirtuins 5, 6 & 7 in breast cancer. Cancer Research, 69(24 Sup), S657. (doi: 10.1158/0008-5472.SABCS-09-3034)

McGlynn, L., Reilly, J., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Shiels, P. (2009) Role of SIRT2, SIRT3 and SIRT4 in breast cancer. Cancer Research, 69(24 Sup), S656-S657. (doi: 10.1158/0008-5472.SABCS-09-3032)

Tannahill, C., Obondo, C., Al-Murri, A., Doughty, J., Lannigan, A., Wilson, C., McMillan, D. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) The relationship between tumour NF-kB expression, hormone status, and clinicopathological factors in primary invasive breast cancer. Cancer Research, 69(2), S263. (doi: 10.1158/0008-5472.SABCS-4038)

Tannahill, C., Obondo, C., Tovey, S., Orange, C., Doughty, J., Wilson, C., Cooke, T., McMillan, D. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) The relationship between tumour NF-kB expression, hormone status and survival in primary invasive breast cancer. Cancer Research, 69(2), S264. (doi: 10.1158/0008-5472.SABCS-4041)

Tatarov, O., Mitchell, T.J., Seywright, M., Leung, H.Y. ORCID logoORCID: https://orcid.org/0000-0002-3933-3975, Brunton, V.G. and Edwards, J. (2009) Src family kinase activity is up-regulated in hormone refractory prostate cancer. Clinical Cancer Research, 15(10), pp. 3540-3549. (doi: 10.1158/1078-0432.CCR-08-1857)

Tovey, S., Marla, S., Brown, S., Burton, P., Canney, P., Stallard, S., Mallon, E., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Cooke, T. (2009) Poor survival outcomes in HER2 positive breast cancer patients with low grade, node negative tumours. Implications for trastuzumab therapy? Cancer Research, 69(2), S98-0. (doi: 10.1158/0008-5472.SABCS-702)

Tovey, S., Tan, B., Campbell, J., Elsberger, B., Brunton, V., Mallon, E., Cooke, T. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2009) Activated c-Src (Y215) kinase expression predicts for early relapse on tamoxifen in human breast cancer. Cancer Research, 69(2), S212-0. (doi: 10.1158/0008-5472.SABCS-3025)

Tovey, S.M., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Brown, S., Mallon, E. and Doughty, J. (2009) Poor survival outcomes in elderly HER2 positive breast cancer patients. Cancer Research, 69(24 Sup), S595. (doi: 10.1158/0008-5472.SABCS-09-2010)

Tovey, S.M., Brown, S.B., Doughty, J.C., Mallon, E.A., Cooke, T.G. and Edwards, J. (2009) Poor survival outcomes in HER2 positive breast cancer patients with low grade, node negative tumours. British Journal of Cancer, 100(5), pp. 680-683. (doi: 10.1038/sj.bjc.6604940)

Watson, C., Kipgen, D., Orange, C., Tovey, S., Cooke, T., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Leung, H. (2009) Role of extracellular signal-regulated kinase 5 (ERK5) in human breast cancer. Cancer Research, 69(2), S264. (doi: 10.1158/0008-5472.SABCS-4042)

Tovey, S., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Brown, S., Mallon, E. and Cooke, T. (2008) Poor survival outcomes in HER2 positive breast cancer patients with low grade, node negative tumours. European Journal of Cancer Supplements, 6(9), pp. 105-106. (doi: 10.1016/S1359-6349(08)71578-7)

Kirkegaard, T., Naresh, A., Sabine, V.S., Tovey, S.M., Edwards, J., Dunne, B., Cooke, T.G., Jones, F.E. and Bartlett, J.M.S. (2008) Expression of tumor necrosis factor [alpha] converting enzyme in endocrine cancers. American Journal of Clinical Pathology, 129, pp. 735-743. (doi: 10.1309/N6YB6YDVF58YCNHN)

Lamb, G.W., McArdle, P.A., Ramsey, S., McNichol, A.M., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Aitchison, M. and McMillan, D.C. ORCID logoORCID: https://orcid.org/0000-0003-4260-5334 (2008) The relationship between the local and systemic inflammatory responses and survival in patients undergoing resection for localized renal cancer. BJU International, 102(6), pp. 756-761. (doi: 10.1111/j.1464-410X.2008.07666.x)

Campbell, E.J., McDuff, E., Tatarov, O., Tovey, S., Brunton, V.G., Cooke, T.G. and Edwards, J. (2008) Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer. British Journal of Cancer, 99(11), pp. 1769-1774. (doi: 10.1038/sj.bjc.6604768)

McCall, P., Gemmell, L.K., Mukherjee, R., Bartlett, J.M.S. and Edwards, J. (2008) Phosphorylation of the androgen receptor is associated with reduced survival in hormonerefractory prostate cancer patients. British Journal of Cancer, 98(6), pp. 1094-1101. (doi: 10.1038/sj.bjc.6604152)

McCall, P., Witton, C.J., Grimsley, S., Nielsen, K.V. and Edwards, J. (2008) Is PTEN loss associated with clinical outcome measures in human prostate cancer? British Journal of Cancer, 99(8), pp. 1296-1301. (doi: 10.1038/sj.bjc.6604680)

McCracken, S.R.C., Ramsay, A., Heer, R., Mathers, M.E., Jenkins, B.L., Edwards, J., Robson, C.N., Marquez, R., Cohen, P. and Leung, H.Y. (2008) Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer. Oncogene, 27(21), pp. 2978-2988. (doi: 10.1038/sj.onc.1210963)

Traynor, P., McGlynn, L.M., Mukherjee, R., Grimsley, S.L.S., Bartlett, J.M.S. and Edwards, J. (2008) An increase in N-Ras expression is associated with development of hormone refractory prostate cancer in a subset of patients. Disease Markers, 24(3), pp. 157-165.

Edwards, J. and Leung, H.Y. (2007) Editorial comment on: increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells. European Urology, 52(6), pp. 1680-1681. (doi: 10.1016/j.eururo.2007.01.098)

Tam, L., McGlynn, L.M., Traynor, P., Mukherjee, R., Bartlett, J.M.S. and Edwards, J. (2007) Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer. British Journal of Cancer, 97(3), pp. 378-383. (doi: 10.1038/sj.bjc.6603871)

Tam, L., McGlynn, L.M., Traynor, P., Mukherjee, R., Bartlett, J.M.S. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2007) Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer. British Journal of Cancer, 97(3), pp. 378-383. (doi: 10.1038/sj.bjc.6603871)

Teo, K., Gemmell, L., Mukherjee, R., Traynor, P. and Edwards, J. (2007) Bad expression influences time to androgen escape in prostate cancer. BJU International, 100(3), pp. 691-696. (doi: 10.1111/j.1464-410X.2007.07001.x)

Edwards, J., Traynor, P., Munro, A., Pirrett, C.F., Dunne, B. and Bartlett, J.M.S. (2006) The role of HER1-HER4 and EGFRvIII in hormone-refractory prostate cancer. Clinical Cancer Research, 12(1), pp. 123-130. (doi: 10.1158/1078-0432.CCR-05-1445)

Kirkegaard, T., Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Tovey, S., McGlynn, L.M., Krishna, S.N., Mukherjee, R., Tam, L., Munro, A.F., Dunne, B. and Bartlett, J.M. (2006) Observer variation in immunohistochemical analysis of protein expression, time for a change? Histopathology, 48(7), pp. 787-794. (doi: 10.1111/j.1365-2559.2006.02412.x)

Bartlett, J.M., Brawley, D., Grigor, K.M., Munro, A.F., Dunne, B. and Edwards, J. (2005) Type I receptor tyrosine kinases are associated with hormone escape in prostate cancer. Journal of Pathology, 205(4), pp. 522-529. (doi: 10.1002/path.1735)

Edwards, J. and Bartlett, J.M.S. (2005) The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: modifications to the androgen receptor. BJU International, 95(9), pp. 1320-1326. (doi: 10.1111/j.1464-410X.2005.05526.x)

Edwards, J. and Bartlett, J.M.S. (2005) The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: androgen-receptor cofactors and bypass pathways. BJU International, 95(9), pp. 1327-1335. (doi: 10.1111/j.1464-410X.2005.05527.x)

Mukherjee, R., Bartlett, J.M.S., Krishna, N.S., Underwood, M.A. and Edwards, J. (2005) Raf-1 expression may influence progression to androgen insensitive prostate cancer. Prostate, 64(1), pp. 101-107. (doi: 10.1002/pros.20211)

Mukherjee, R., Edwards, J., Underwood, M.A. and Bartlett, J.M.S. (2005) The relationship between angiogenesis and cyclooxygenase-2 expression in prostate cancer. BJU International, 96(1), pp. 62-66. (doi: 10.1111/j.1464-410X.2005.05568.x)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Mukherjee, R., Munro, A.F., Wells, A.C., Almushatat, A. and Bartlett, J.M.S. (2004) HER2 and COX2 expression in human prostate cancer. European Journal of Cancer, 40(1), pp. 50-55. (doi: 10.1016/j.ejca.2003.08.010)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Krishna, N.S., Grigor, K.M. and Bartlett, J.M.S. (2003) Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. British Journal of Cancer, 89(3), pp. 552-556. (doi: 10.1038/sj.bjc.6601127)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Krishnan, S., Witton, C.J. and Bartlett, J.M.S. (2003) Gene amplifications associated with the development of hormone- resistant prostate cancer. Clinical Cancer Research, 9(14), pp. 5271-5281.

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Duncan, P., Going, J.J., Watters, A.D., Grigor, K.M. and Bartlett, J.M.S. (2002) Identification of loci associated with putative recurrence genes in transitional cell carcinoma of the urinary bladder. Journal of Pathology, 196(4), pp. 380-385. (doi: 10.1002/path.1052)

Brown, R.S.D., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Bartlett, J.M.S., Jones, C. and Dogan, A. (2002) Routine acid decalcification of bone marrow samples can preserve DNA for FISH and CGH studies in metastatic prostate cancer. Journal of Histochemistry and Cytochemistry, 50(1), pp. 113-115.

Brown, R.S.D., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Dogan, A., Payne, H., Harland, S.J., Bartlett, J.M.S. and Masters, J.R.W. (2002) Amplification of the androgen receptor gene in bone metastases from hormone-refractory prostate cancer. Journal of Pathology, 198(2), pp. 237-244. (doi: 10.1002/path.1206)

Mir, K., Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Paterson, P.J. ORCID logoORCID: https://orcid.org/0000-0002-9918-537X, Hehir, M., Underwood, M.A. and Bartlett, J.M.S. (2002) The CAG trinucleotide repeat length in the androgen receptor does not predict the early onset of prostate cancer. BJU International, 90(6), pp. 573-578. (doi: 10.1046/j.1464-410X.2002.02981.x)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Duncan, P., Going, J.J., Grigor, K.M., Watters, A.D. and Bartlett, J.M.S. (2001) Loss of heterozygosity on chromosomes 11 and 17 are markers of recurrence in TCC of the bladder. British Journal of Cancer, 85(12), pp. 1894-1899. (doi: 10.1054/bjoc.2001.2159)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Krishna, N.S., Mukherjee, R., Watters, A.D., Underwood, M.A. and Bartlett, J.M.S. (2001) Amplification of the androgen receptor may not explain the development of androgen-independent prostate cancer. BJU International, 88(6), pp. 633-637. (doi: 10.1046/j.1464-410X.2001.02350.x)

Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 and Bartlett, J.M.S. (1999) Induction of apoptosis and inhibition of cellular proliferation as a dual approach to treatment of ovarian cancer. International Journal of Oncology, 15(3), pp. 583-588.

Book Sections

Marsella-Hatziieremia, S., McCall, P. and Edwards, J. ORCID logoORCID: https://orcid.org/0000-0002-7192-6906 (2011) Signalling pathways and gene expression profiles in prostate cancer. In: Spiess, P. (ed.) Prostate Cancer: From Bench to Bedside. InTech, pp. 93-114. ISBN 9789533073316 (doi: 10.5772/26971)

Conference or Workshop Item

Iwata, T. et al. (2025) Does Immune Suppression in the Pre-malignant Microenvironment of Colorectal Neoplastic Lesions Associate with Development of Metachronous Polyp and Cancer Risk? 216th Scientific Meeting of the Pathological Society of Great Britain & Ireland, Royal Society of Medicine, London UK, 21-22 Jan 2025.

Bilsland, Alan ORCID logoORCID: https://orcid.org/0000-0003-0957-3908, Kelly, Caroline ORCID logoORCID: https://orcid.org/0000-0002-5330-7888, Roccisana, Jennifer, Paul, James ORCID logoORCID: https://orcid.org/0000-0001-7367-5816, Jones, Robert ORCID logoORCID: https://orcid.org/0000-0002-2904-6980, Edwards, Joanne ORCID logoORCID: https://orcid.org/0000-0002-7192-6906, Roseweir, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6158-1564, Stein, Torsten ORCID logoORCID: https://orcid.org/0000-0002-9946-1549 and West, Katherine ORCID logoORCID: https://orcid.org/0000-0002-5994-8969 (2018) An Exploratory Study on the Use of Game-based Learning Using Microsoft Kinect to Teach Oncology Phase I Clinical Trial Designs. 2018 NCRI Cancer Conference, Glasgow, UK, 04-06 Nov 2018. (doi: 10.1038/s41416-018-0299-z)

This list was generated on Sun Jun 15 00:02:19 2025 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • The role of socioeconomic deprivation in future cancer and advanced adenoma risk following bowel screening colonoscopy - biology, healthcare systems, and the patient
    Bowel Cancer UK
    2025 - 2027
     
  • Investigating tumour epithelial, immune and stroma spatial transcriptomics of poor prognosis BRAF V600E mutated colorectal cancer
    Beatson Cancer Charity
    2025 - 2026
     
  • Exploring the association between post-operative complications and oncological outcomes in breast cancer surgery
    Royal College of Physicians and Surgeons of Glasgow
    2024 - 2025
     
  • Exploring the association between post-operative complications and oncological outcomes in breast cancer surgery
    BASO - The Association for Cancer Surgery
    2024 - 2026
     
  • Requirement for a new digital slide scanner within the Glasgow Tissue Research Facility
    Beatson Cancer Charity
    2024 - 2025
     
  • An investigation into the underlying mechanisms of tumour budding in colorectal cancer using high-plex single cell imaging.
    NHS Greater Glasgow and Clyde Endowment Funds
    2024 - 2025
     
  • Investigating immunological prevention strategies for precursor lesions of colon cancer
    Cancer Research UK
    2024 - 2025
     
  • Single cell spatial transcriptomics to investigate colorectal adenoma immune contexture and its association with future polyp or cancer risk in bowel screening patients
    Guts UK Charity
    2024 - 2025
     
  • D04: Derivation of novel non-invasive radiomic and AI-based classifiers to determine molecular behaviour of rectal cancer and its treatment response to radiotherapy
    Cancer Research UK
    2024 - 2028
     
  • Molecular characterisation of colonic polyps to understand metachronous disease and CRC development
    Beatson Cancer Charity
    2023 - 2024
     
  • ECMC QQR 2023-2028
    Cancer Research UK
    2023 - 2024
     
  • Utilising AI for the Detection of Novel Biomarkers in Cancer
    Beatson Cancer Charity
    2023 - 2024
     
  • Integrated Technologies for Improved Polyp Surveillance (INCISE) V2.0
    Innovate UK
    2023 - 2025
     
  • IL6/JAK/STAT3 pathway in colorectal cancer
    Office of the Chief Scientific Adviser
    2023 - 2025
     
  • Development and validation of prognostic biomarkers for metastatic stratification in colorectal cancer patients.
    Bowel Cancer UK
    2023 - 2024
     
  • An investigation into the therapeutic potential of combining radiotherapy and IKK inhibition for rectal cancer patients
    Office of the Chief Scientific Adviser
    2023 - 2025
     
  • Development of a first-in-class preclinical IKKa inhibitor for the treatment of castrate-resistant prostate cancer
    Prostate Cancer UK
    2022 - 2022
     
  • CRUK Centre Renewal 2021
    Cancer Research UK
    2022 - 2023
     
  • Combining Radiation with JAK inhibitors as a novel therapeutic strategy
    Cancer Research UK
    2022 - 2022
     
  • Inhibition of STAT3 in combination with radiotherapy as a novel therapeutic approach for colorectal cancer
    Wellcome Trust
    2022 - 2022
     
  • TransSCOT - Scot Genomics
    Beatson Institute for Cancer Research
    2022 - 2023
     
  • McNab Funding - Disease Positioning Project
    Beatson Institute for Cancer Research
    2021 - 2022
     
  • Utilising spatial transcriptomics to investigate underlying mechanisms of aberrant STAT3 signalling in colorectal cancer
    NHS Greater Glasgow and Clyde Endowment Funds
    2021 - 2022
     
  • Integrating digital pathology and genomic analysis to optimise and streamline colonic surveillance within the Scottish Bowel Screening Programme (SBoSP) to enable early detection of Colorectal neoplasia.
    Innovate UK
    2020 - 2023
     
  • Investigation into the potential immune primimg effect of chemo/radiotherapy on the tumour in rectal cancer
    NHS Greater Glasgow and Clyde Endowment Funds
    2020 - 2021
     
  • Prognostic biomarkers in primary operable triple negative breast cancer
    Royal College of Physicians and Surgeons of Glasgow
    2019 - 2021
     
  • Translational Scot Trial
    University of Oxford
    2019 - 2021
     
  • Research donation to investigate inflammatory signalling pathways in breast cancer - E Morrow
    NHS Greater Glasgow and Clyde
    2018 - 2019
     
  • The development of a new pre-clinical model to identify predicative biomakers for Prostate Cancer
    NHS Greater Glasgow and Clyde
    2018 - 2018
     
  • Scottish Genomics Project Part time Research Doctor
    NHS Greater Glasgow and Clyde Endowment Funds
    2017 - 2018
     
  • The role of IKK-a and p45-IKK-a in colorectal cancer
    NHS Greater Glasgow and Clyde Endowment Funds
    2017 - 2018
     
  • Androgen receptor phosphorylation as a predictor of response to prostate cancer treatment, Dr Payne
    NHS Greater Glasgow and Clyde Endowment Funds
    2016 - 2017
     
  • Developing a quantitative fluorescent microscopy technique for androgen receptor assessment in prostate cancer
    NHS Greater Glasgow and Clyde Endowment Funds
    2016 - 2017
     
  • Identification of biomarkers to predict response to synergistic targeting of AR and PI3K pathway in castrate resistant prostate cancer.
    Prostate Cancer UK
    2015 - 2018
     
  • First-in-class Selective IKKalpha Inhibitors for the Treatment of Castrate Resistant Prostate Cancer (CRPC) and Pancreatic Cancer
    Medical Research Council
    2015 - 2017
     
  • Estabilishing prostate cancer patient derived cell lines and xenografts for use in validation of predictive biomarkers (Confidence in Concept)
    Medical Research Council
    2014 - 2015
     
  • CXCL 12 as an assay system for IKKalpha inhibitor drugs
    Cancer Research UK
    2014 - 2016
     
  • The relationship between genetic aberrations and CpG Island Methylator Phenotype in colorectal cancer
    Cancer Research UK
    2012 - 2013
     
  • The relationship between clinicopathological factors, microsatellite instability status and survival in patients with colorectal cancer.
    Royal College of Physicians and Surgeons of Glasgow
    2012 - 2013
     
  • The role of NF-kB and MMP-9 in predicting recurrence from Ulcerative Colitis following colectomy
    Cunningham Trust
    2012 - 2013
     
  • The role of IKKa and IKKb in prostate cancer progression
    Prostate Cancer UK
    2011 - 2014
     
  • The role of Src kinase family in Colorectal cancer.
    Royal College of Surgeons of Edinburgh
    2011 - 2012
     
  • The role of the androgen receptor in benign prostatic hyperplasia
    Cunningham Trust
    2011 - 2014
     
  • Use of cellular proliferation index as a novel method for improving clinical management of prosthetic enlargement
    Cunningham Trust
    2010 - 2011
     
  • A comprehensive multidisciplinary approach to target the inhibitory kappa B kinase pathway to discover novel therapies in prostate cancer
    Cancer Research UK
    2010 - 2014
     
  • Testing the potential of PAR-2 as a therapeutic target in prostate cancer
    Cancer Research UK
    2010 - 2012
     
  • The role of Src kinase family members & downstream pathway effectors in the development & progression of prostate cancer.
    NHS Greater Glasgow and Clyde Endowment Funds
    2009 - 2011
     
  • Src Kinase and downstream pathway effectors in prostate cancer
    Royal College of Physicians & Surgeons of Glasgow
    2009 - 2010
     
  • Is phosphorylation of the androgen receptor of clinical significance in the development and progression of prostrate cancer?
    Association for International Cancer Research
    2008 - 2010
     
  • The role of the Src kinase family in breast cancer.
    Royal College of Surgeons of Edinburgh
    2007 - 2011
     
  • Validation of the MEK5/ERK5 pathway as targets for therapy in prostate cancer
    Prostate Cancer Charity
    2007 - 2010
     
  • The role of NF-kB expression and interaction with the inflammatory response to breast cancer.
    Western Infirmary
    2007 - 2010
     
  • Prostate cancer research project
    Cruden Foundation Limited
    2006 - 2009
     
  • The role of Src family kinases in the development of androgen independent prostate cancer
    Cancer Research UK
    2006 - 2007
     
  • The role of the P13K/Akt pathway in the development of hormone refractory prostate cancer
    Association for International Cancer Research
    2005 - 2007
     
  • What are the molecular mechanisms responsible for development/progression of prostate cancer?
    Royal College of Physicians & Surgeons of Glasgow
    2005 - 2007
     
  • Is the P13K/Akt pathway involved in the development of hormone refactory prostate cancer?
    NHS Trust Prostate Cancer Fund
    2005 - 2005
     
  • Signal Transduction in Cancer
    The Royal Society
    2005 - 2005
     
  • Is the P13K/Akt pathway involved in the development of hormone refactory prostate cancer?
    Prostate Cancer Charitable Trust
    2004 - 2005
     
  • What are the roles of the P13K/Akt and RAS/RAF/MAP kinase pathways in the development of hormone refractory prostate cancer
    Tenovus Scotland
    2002 - 2005
     

Supervision

  • Al Badran, Sara Samir Foad
    Examining the colonic polyp microbiome and its association with future colorectal neoplasia risk in a bowel screening population

Since 2007, Joanne has supervised 26 PhD students, 8 MD students, 26 RA posts and 8 technical posts.

Teaching

Joanne is Director of Education for the School of Cancer Sciences at the University of Glasgow.

Research datasets

Jump to: 2024 | 2023 | 2021 | 2019
Number of items: 15.

2024

Edwards, J. and Grimwood, P. (2024) INCISE mutational data – INCISE II Batch 4&5 (Jul 2024). [Data Collection]

Edwards, J. and Grimwood, P. (2024) INCISE mutational data – INCISE II Batch 3 (Feb 2024). [Data Collection]

2023

Edwards, J. and Grimwood, P. (2023) INCISE mutational data – INCISE II Batch 2 (Oct 2023). [Data Collection]

Edwards, J. and Grimwood, P. (2023) INCISE mutational data – INCISE II Batch 1 (Sep 2023). [Data Collection]

Edwards, J. and Ritchie, A. (2023) INCISE mutational data – Longitudinal polyp study (Nov 2021). [Data Collection]

2021

Edwards, J. (2021) ER positive tamoxifen treated breast cancer TMA. [Data Collection]

Edwards, J. and Savioli, F. (2021) Triple negative breast cancer cohort. [Data Collection]

Park, J. and Edwards, J. (2021) Colorectal cancer GRI TMA cohort. [Data Collection]

Pennel, K., Park, J. and Edwards, J. (2021) Colorectal cancer budding cohort. [Data Collection]

Edwards, J. and Ritchie, A. (2021) INCISE mutational data (Nov 2021). [Data Collection]

Edwards, J. (2021) Matched hormone naïve and castrate resistant prostate cancer specimens. [Data Collection]

2019

Edwards, J. (2019) Glasgow Royal Infirmary Prostate Cancer array. [Data Collection]

Edwards, J. and Campbell, J. (2019) 1800 breast array. [Data Collection]

Edwards, J. and Payne, S. (2019) The SP cohort. [Data Collection]

Edwards, J. and Powel, A. (2019) Combined colorectal cancer array. [Data Collection]

This list was generated on Sat Jun 14 22:44:17 2025 BST.

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Translational Cancer Pathology