Dr Jean Quinn

  • Technical Research and Teaching Specialist (Pathology)
  • Research Associate (Institute of Cancer Sciences)

telephone: 01413308607
email: Jean.Quinn@glasgow.ac.uk

School of Medicine, Dentistry & Nursing, Level 1, Wolfson Wohl Cancer Research Centre, Garscube Campus, Glasgow, G61 1QH

ORCID iDhttps://orcid.org/0000-0002-8267-0993

Publications

List by: Type | Date

Jump to: 2020 | 2019 | 2018 | 2017 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008
Number of items: 22.

2020

Quinn, J. A. , Bennett, L., Patel, M., Frixou, M., Park, J. H., Roseweir, A., Horgan, P. G., McMillan, D. C. and Edwards, J. (2020) The relationship between members of the canonical NF-kB pathway, tumour microenvironment and cancer specific survival in colorectal cancer patients. Histology and Histopathology: Cellular and Molecular Biology, 35(6), pp. 569-578. (doi: 10.14670/HH-18-168) (PMID:31592535)

2019

Alyamani, A.M.A., Quinn, J.A. and Greenhalgh, D.A. (2019) Activated β-catenin Expression Inhibits Papillomas in HK1.ras Transgenic Mice Via Increased p53/p21-Associated Differentiation. British Journal of Dermatology 180(6): e186. Meeting Abstract: British Society for Investigative Dermatology Annual Meeting, Bradford, UK, 01-03 Apr 2019. (doi:10.1111/bjd.17776)

McMenemy, C., Quinn, J.A. and Greenhalgh, D.A. (2019) Epidermal-Specific 14-3-3σ/Stratifin Overexpressioninduces Malignant Conversion of Aggressive, Rapid-growth Papillomas, but not Slower, Regression-prone Papillomas. British Journal of Dermatology 180(6): e203. Meeting Abstract: British Society for Investigative Dermatology Annual Meeting, Bradford, UK, 01-03 Apr 2019. (doi:10.1111/bjd.17776)

Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)

Roseweir, A.K. et al. (2019) A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer. International Journal of Cancer, 144(1), pp. 150-159. (doi: 10.1002/ijc.31739) (PMID:29992570)

2018

Alyamani, A.M.A., Quinn, J.A. and Greenhalgh, D. A. (2018) Analysis of β-catenin expression in transgenic mouse skin carcinogenesis reveals inhibitory roles in papillomatogenesis and oncogenic roles in malignant conversion. BSID Annual Meeting 2018, London, UK, 26-28 Mar 2018.

McMenemy, C., Quinn, J.A. and Greenhalgh, D. A. (2018) Fos co-operation with 14-3-3σ [Stratifin] induces malignant conversion in transgenic mouse skin carcinogenesis: a paradigm for SCC of follicular origin. BSID Annual Meeting 2018, London, UK, 26-28 Mar 2018.

2017

Bennett, L., Quinn, J. , McCall, P., Mallon, E. A., Horgan, P. G. , McMillan, D. C. , Paul, A. and Edwards, J. (2017) High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer. International Journal of Cancer, 140(7), pp. 1633-1644. (doi: 10.1002/ijc.30578) (PMID:28006839)

Park, J. H. , Van Wyk, H. C., McMillan, D. C. , Quinn, J. A. , Clark, J., Roxburgh, C. , Horgan, P. G. and Edwards, J. (2017) Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host. Clinical Cancer Research, 23(7), pp. 1698-1709. (doi: 10.1158/1078-0432.CCR-16-1416) (PMID:27678454)

McMenemy, C., Guo, D., Cochrane, A., Crookston, K., Boyle, J., Quinn, J. and Greenhalgh, D. A. (2017) 14-3-3σ/Stratifin Expression in HK1.Ras/Fos-Δ5ptenflx Transgenic Mouse Skin Carcinogenesis Reveals an Early, Inhibitory Role; Lost During MDM2 Activated/P53 Inactivated Malignant Progression. British Society for Investigative Dermatology (BSID) Annual Meeting, Manchester, UK, 3-5 April 2017.

2014

Macdonald, F., Yao, D., Quinn, J. and Greenhalgh, D. (2014) PTEN ablation in RasHa/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition. Oncogene, 33(32), pp. 4132-4143. (doi: 10.1038/onc.2013.372)

2013

Macdonald, F.H., Yao, D., Quinn, J.A. and Greenhalgh, D.A. (2013) Activated p-AKT, but not MDM2, drives malignant progression in Ras/Fos/PTENnull skin carcinogenesis via p53/p21 loss and elevated cyclin D1/E2 expression. Journal of Investigative Dermatology, 133(S1), S57-S57. (doi: 10.1038/jid.2013.96)

Nobis, M. et al. (2013) Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of Src in pancreatic cancer. Cancer Research, 73(15), pp. 4674-4686. (doi: 10.1158/0008-5472.CAN-12-4545)

2011

MacDonald, F.H., Quinn, J.A. and Greenhalgh, D.A. (2011) Skin carcinogenesis in Ras/fos/PTENnull transgenic mice associates reveals mTOR association with papillomatogenesis/conversion and AKT with malignant progression. British Journal of Dermatology, 164(4), p. 934. (doi: 10.1111/j.1365-2133.2011.10279.x)

Edward, M., Quinn, J.A. and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19(3), pp. 379-386. (doi: 10.1111/j.1524-475X.2011.00678.x)

Timpson, P. et al. (2011) Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research, 71(3), pp. 747-757. (doi: 10.1158/0008-5472.CAN-10-2267)

2010

Edward, M., Quinn, J.A. , Pasonen-Seppanen, S.M., McCann, B.A. and Tammi, R.H. (2010) 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors. British Journal of Dermatology, 162(6), pp. 1224-1232. (doi: 10.1111/j.1365-2133.2010.09699.x)

Katz, E. et al. (2010) A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. British Journal of Cancer, 103(3), p. 401. (doi: 10.1038/sj.bjc.6605763)

2009

Greenhalgh, D. , Yao, D., Quinn, J. and Macdonald, F. (2009) RasHa activation interdicts compensatory p53/p21WAF expression in Fos/PTENnull skin carcinogenesis via initial p53 loss but retention of p21WAF limits malignant progression. In: American Association for Cancer Research (AACR) 100th Annual Meeting, Denver, USA, 18-22 April 2009,

Macdonald, F., Yao, D., Quinn, J. and Greenhalgh, D. (2009) Compensatory p53/p21WAF-induced differentiation in Fos/PTENnull skin carcinogenesis is interdicted by RasHa activation but retention of p21WAF inhibits malignant progression. In: British Society for Investigative Dermatology (BSID) Annual Meeting, Royal Agricultural College, Cirencester, UK, 30 March - 1 April 2009,

2008

Edward, M., Quinn, J.A. , Mukherjee, S., Jensen, M.B., Jardine, A.G. , Mark, P. and Burden, A. (2008) Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. Journal of Pathology, 214(5), pp. 584-593. (doi: 10.1002/path.2311)

Yao, D., Alexander, C., Quinn, J. , Chan, W., Wu, H. and Greenhalgh, D. (2008) Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21(WAF)-induced differentiation triggered by GSK3 beta inactivation and reduced AKT activity. Journal of Cell Science, 121(10), pp. 1758-1769.

This list was generated on Wed Sep 16 14:07:39 2020 BST.
Number of items: 26.

Articles

Matly, A., Quinn, J. A. , McMillan, D. C. , Park, J. H. and Edwards, J. (2021) The relationship between β-catenin and patient survival in colorectal cancer systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 163, 103337. (doi: 10.1016/j.critrevonc.2021.103337) (PMID:33992802)

Moreno, R., Banerjee, S., Jackson, A. W., Quinn, J. , Baillie, G., Dixon, J. E., Dinkova-Kostova, A. T., Edwards, J. and de la Vega, L. (2021) The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress. Cell Death and Differentiation, 28(5), pp. 1563-1578. (doi: 10.1038/s41418-020-00686-8) (PMID:33268814)

Al-Badran, S. S.F. et al. (2021) Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 7(2), pp. 121-134. (doi: 10.1002/cjp2.193) (PMID:33338327)

Torrente, L. et al. (2020) High NRF2 levels correlate with poor prognosis in colorectal cancer patients and with sensitivity to the kinase inhibitor AT9283 in vitro. Biomolecules, 10(10), 1365. (doi: 10.3390/biom10101365) (PMID:32992842) (PMCID:PMC7600603)

Quinn, J. A. , Bennett, L., Patel, M., Frixou, M., Park, J. H., Roseweir, A., Horgan, P. G., McMillan, D. C. and Edwards, J. (2020) The relationship between members of the canonical NF-kB pathway, tumour microenvironment and cancer specific survival in colorectal cancer patients. Histology and Histopathology: Cellular and Molecular Biology, 35(6), pp. 569-578. (doi: 10.14670/HH-18-168) (PMID:31592535)

Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)

Roseweir, A.K. et al. (2019) A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer. International Journal of Cancer, 144(1), pp. 150-159. (doi: 10.1002/ijc.31739) (PMID:29992570)

Bennett, L., Quinn, J. , McCall, P., Mallon, E. A., Horgan, P. G. , McMillan, D. C. , Paul, A. and Edwards, J. (2017) High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer. International Journal of Cancer, 140(7), pp. 1633-1644. (doi: 10.1002/ijc.30578) (PMID:28006839)

Park, J. H. , Van Wyk, H. C., McMillan, D. C. , Quinn, J. A. , Clark, J., Roxburgh, C. , Horgan, P. G. and Edwards, J. (2017) Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host. Clinical Cancer Research, 23(7), pp. 1698-1709. (doi: 10.1158/1078-0432.CCR-16-1416) (PMID:27678454)

Macdonald, F., Yao, D., Quinn, J. and Greenhalgh, D. (2014) PTEN ablation in RasHa/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition. Oncogene, 33(32), pp. 4132-4143. (doi: 10.1038/onc.2013.372)

Macdonald, F.H., Yao, D., Quinn, J.A. and Greenhalgh, D.A. (2013) Activated p-AKT, but not MDM2, drives malignant progression in Ras/Fos/PTENnull skin carcinogenesis via p53/p21 loss and elevated cyclin D1/E2 expression. Journal of Investigative Dermatology, 133(S1), S57-S57. (doi: 10.1038/jid.2013.96)

Nobis, M. et al. (2013) Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of Src in pancreatic cancer. Cancer Research, 73(15), pp. 4674-4686. (doi: 10.1158/0008-5472.CAN-12-4545)

MacDonald, F.H., Quinn, J.A. and Greenhalgh, D.A. (2011) Skin carcinogenesis in Ras/fos/PTENnull transgenic mice associates reveals mTOR association with papillomatogenesis/conversion and AKT with malignant progression. British Journal of Dermatology, 164(4), p. 934. (doi: 10.1111/j.1365-2133.2011.10279.x)

Edward, M., Quinn, J.A. and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19(3), pp. 379-386. (doi: 10.1111/j.1524-475X.2011.00678.x)

Timpson, P. et al. (2011) Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research, 71(3), pp. 747-757. (doi: 10.1158/0008-5472.CAN-10-2267)

Edward, M., Quinn, J.A. , Pasonen-Seppanen, S.M., McCann, B.A. and Tammi, R.H. (2010) 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors. British Journal of Dermatology, 162(6), pp. 1224-1232. (doi: 10.1111/j.1365-2133.2010.09699.x)

Katz, E. et al. (2010) A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. British Journal of Cancer, 103(3), p. 401. (doi: 10.1038/sj.bjc.6605763)

Edward, M., Quinn, J.A. , Mukherjee, S., Jensen, M.B., Jardine, A.G. , Mark, P. and Burden, A. (2008) Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. Journal of Pathology, 214(5), pp. 584-593. (doi: 10.1002/path.2311)

Yao, D., Alexander, C., Quinn, J. , Chan, W., Wu, H. and Greenhalgh, D. (2008) Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21(WAF)-induced differentiation triggered by GSK3 beta inactivation and reduced AKT activity. Journal of Cell Science, 121(10), pp. 1758-1769.

Conference or Workshop Item

Alyamani, A.M.A., Quinn, J.A. and Greenhalgh, D.A. (2019) Activated β-catenin Expression Inhibits Papillomas in HK1.ras Transgenic Mice Via Increased p53/p21-Associated Differentiation. British Journal of Dermatology 180(6): e186. Meeting Abstract: British Society for Investigative Dermatology Annual Meeting, Bradford, UK, 01-03 Apr 2019. (doi:10.1111/bjd.17776)

McMenemy, C. , Quinn, J.A. and Greenhalgh, D.A. (2019) Epidermal-Specific 14-3-3σ/Stratifin Overexpressioninduces Malignant Conversion of Aggressive, Rapid-growth Papillomas, but not Slower, Regression-prone Papillomas. British Journal of Dermatology 180(6): e203. Meeting Abstract: British Society for Investigative Dermatology Annual Meeting, Bradford, UK, 01-03 Apr 2019. (doi:10.1111/bjd.17776)

Alyamani, A.M.A., Quinn, J.A. and Greenhalgh, D. A. (2018) Analysis of β-catenin expression in transgenic mouse skin carcinogenesis reveals inhibitory roles in papillomatogenesis and oncogenic roles in malignant conversion. BSID Annual Meeting 2018, London, UK, 26-28 Mar 2018.

McMenemy, C. , Quinn, J.A. and Greenhalgh, D. A. (2018) Fos co-operation with 14-3-3σ [Stratifin] induces malignant conversion in transgenic mouse skin carcinogenesis: a paradigm for SCC of follicular origin. BSID Annual Meeting 2018, London, UK, 26-28 Mar 2018.

McMenemy, C. , Guo, D., Cochrane, A., Crookston, K., Boyle, J., Quinn, J. and Greenhalgh, D. A. (2017) 14-3-3σ/Stratifin Expression in HK1.Ras/Fos-Δ5ptenflx Transgenic Mouse Skin Carcinogenesis Reveals an Early, Inhibitory Role; Lost During MDM2 Activated/P53 Inactivated Malignant Progression. British Society for Investigative Dermatology (BSID) Annual Meeting, Manchester, UK, 3-5 April 2017.

Conference Proceedings

Greenhalgh, D. , Yao, D., Quinn, J. and Macdonald, F. (2009) RasHa activation interdicts compensatory p53/p21WAF expression in Fos/PTENnull skin carcinogenesis via initial p53 loss but retention of p21WAF limits malignant progression. In: American Association for Cancer Research (AACR) 100th Annual Meeting, Denver, USA, 18-22 April 2009,

Macdonald, F., Yao, D., Quinn, J. and Greenhalgh, D. (2009) Compensatory p53/p21WAF-induced differentiation in Fos/PTENnull skin carcinogenesis is interdicted by RasHa activation but retention of p21WAF inhibits malignant progression. In: British Society for Investigative Dermatology (BSID) Annual Meeting, Royal Agricultural College, Cirencester, UK, 30 March - 1 April 2009,

This list was generated on Fri Sep 17 18:19:54 2021 BST.