Dr Ed Roberts
- Senior Lecturer (CRUK Scotland Institute)
email:
Ed.Roberts@glasgow.ac.uk
pronouns:
He/him/his
Research interests
Research groups
Publications
2025
Janas, P. P. et al. (2025) Epithelial memory after respiratory viral infection in mice results in prolonged enhancement of antigen presentation. Allergy, 80(9), pp. 2501-2518. (doi: 10.1111/all.16683) (PMID:40772364) (PMCID:PMC12444829)
Weir, Daniel, Bentley-Abbot, Calum, McCowan, Jack, Loney, Colin ORCID: https://orcid.org/0000-0002-0508-1781, Roberts, Edward
ORCID: https://orcid.org/0000-0002-8229-1715 and Hutchinson, Edward
ORCID: https://orcid.org/0000-0003-3673-9096
(2025)
Induction of tunnelling nanotube-like structures by influenza A viruses requires the onset of apoptosis.
PLoS Pathogens, 21(6),
e1013191.
(doi: 10.1371/journal.ppat.1013191)
(PMID:40472024)
(PMCID:PMC12169559)
Lau, V. W. C. et al. (2025) Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models. Nature Communications, 16(1), 2. (doi: 10.1038/s41467-024-54791-0) (PMID:39746898) (PMCID:PMC11696141)
Turnbull, M. L. et al. (2025) The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution. Nature Communications, 16, 11042. (doi: 10.1038/s41467-025-67234-1) (PMID:41398153) (PMCID:PMC12706089)
2024
Turnbull, M. L. et al. (2024) Polygenic determinants OF H5N1 adaptation to bovine cells. bioRxiv, (doi: 10.1101/2024.11.29.626120) (PMID:PPR948676)
Hargrave, Kerrie E., Worrell, Julie C. ORCID: https://orcid.org/0000-0001-7754-1364, Pirillo, Chiara, Brennan, Euan, Masdefiol Garriga, Andreu
ORCID: https://orcid.org/0000-0002-2094-3001, Gray, Joshua I., Purnell, Thomas, Roberts, Edward W.
ORCID: https://orcid.org/0000-0002-8229-1715 and MacLeod, Megan K.L.
ORCID: https://orcid.org/0000-0003-1843-8580
(2024)
Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells.
Mucosal Immunology, 17(5),
pp. 843-857.
(doi: 10.1016/j.mucimm.2024.06.001)
(PMID:38851589)
(PMCID:PMC11464401)
Kumar, S. et al. (2024) Specialized Tfh cell subsets driving type-1 and type-21 humoral responses in lymphoid tissue. Cell Discovery, 10, 64. (doi: 10.1038/s41421-024-00681-0) (PMID:38834551) (PMCID:PMC11150427)
Bentley-Abbot, Calum, Heslop, Rhiannon, Pirillo, Chiara, Chandrasegaran, Praveena, McConnell, Gail, Roberts, Ed ORCID: https://orcid.org/0000-0002-8229-1715, Hutchinson, Edward
ORCID: https://orcid.org/0000-0003-3673-9096 and MacLeod, Annette
ORCID: https://orcid.org/0000-0002-0150-5049
(2024)
An easy to use tool for the analysis of subcellular mRNA transcript colocalisation in smFISH data.
Scientific Reports, 14,
8348.
(doi: 10.1038/s41598-024-58641-3)
(PMID:38594373)
(PMCID:PMC11004122)
Mahmood, M. et al. (2024) Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature Cancer, 5(4), pp. 659-672. (doi: 10.1038/s43018-023-00721-w) (PMID:38286828) (PMCID:PMC11056318)
Leung, E. Y.l. et al. (2024) Chemokine CCL21 Induces an Immunotolerant Tumour Microenvironment Leading to Poorer Survival in Ovarian Cancer. ESGO 2024 Congress, Barcelona, Spain, 7-10 March 2024. (doi: 10.1136/ijgc-2024-esgo.985)
2023
Shergold, Amy, Devlin, Ryan, Young, Alex and Roberts, Ed W. ORCID: https://orcid.org/0000-0002-8229-1715
(2023)
Chemotaxis: Dendritic cells as trendsetters of the immune response.
Current Biology, 33(18),
PR957-PR959.
(doi: 10.1016/j.cub.2023.08.009)
(PMID:37751709)
Young, Alexander L., Lorimer, Tara, Al-Khalidi, Sarwah K. and Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715
(2023)
De novo priming: driver of immunotherapy responses or epiphenomenon?
Essays In Biochemistry, 67(6),
pp. 929-939.
(doi: 10.1042/EBC20220244)
(PMID:37139854)
(PMCID:PMC10539938)
Pirillo, C. et al. (2023) Cotransfer of antigen and contextual information harmonizes peripheral and lymph node conventional dendritic cell activation. Science Immunology, 8(85), eadg8249. (doi: 10.1126/sciimmunol.adg8249) (PMID:37478193) (PMCID:PMC7616026)
Cheng, Z. et al. (2023) Fluorogenic granzyme a substrates enable real‐time imaging of adaptive immune cell activity. Angewandte Chemie International Edition, 62(8), e202216142. (doi: 10.1002/anie.202216142) (PMID:36562327) (PMCID:PMC10108010)
2022
Sims, A. et al. (2022) Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biology, 21(2), e3001941. (doi: 10.1371/journal.pbio.3001941) (PMID:36757937) (PMCID:PMC9910727)
Leslie, J. et al. (2022) CXCR2 inhibition enables NASH-HCC immunotherapy. Gut, 71(10), pp. 2093-2106. (doi: 10.1136/gutjnl-2021-326259) (PMID:35477863) (PMCID:PMC9484388)
Yi, Rulan, Chen, Emily, Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Krummel, Matthew F. and Kathrin Serwas, Nina
(2022)
Impact of protein identity on tumor-associated antigen uptake into infiltrating immune cells: A comparison of different fluorescent proteins as model antigens.
PLoS ONE, 17(8),
e0272857.
(doi: 10.1371/journal.pone.0272857)
(PMID:35976946)
(PMCID:PMC9384993)
Bravo-Blas, Alberto, Pirillo, Chiara, Shergold, Amy, Andrusaite, Anna and Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715
(2022)
Think global but act local: Tuning the dendritic cell response in cancer.
International Journal of Biochemistry and Cell Biology, 147,
106227.
(doi: 10.1016/j.biocel.2022.106227)
(PMID:35605877)
Pirillo, C. et al. (2022) Metalloproteinase inhibition reduces AML growth, prevents stem cell loss and improves chemotherapy effectiveness. Blood Advances, 6(10), pp. 3126-3141. (doi: 10.1182/bloodadvances.2021004321) (PMID:35157757) (PMCID:PMC9131921)
Devlin, Ryan and Roberts, Ed ORCID: https://orcid.org/0000-0002-8229-1715
(2022)
Building a healthy mouse model ecosystem to interrogate cancer biology.
Disease Models and Mechanisms, 15(9),
dmm049795.
(doi: 10.1242/dmm.049795)
(PMID:36098988)
(PMCID:PMC9509886)
Scott, J. I. et al. (2022) A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies. Nature Communications, 13(1), 2366. (doi: 10.1038/s41467-022-29691-w) (PMID:35501326) (PMCID:PMC9061857)
2021
Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)
Pinkard, H. et al. (2021) Learned adaptive multiphoton illumination microscopy for large-scale immune response imaging. Nature Communications, 12(1), 1916. (doi: 10.1038/s41467-021-22246-5) (PMID:33772022) (PMCID:PMC7997974)
2019
Binnewies, M. et al. (2019) Unleashing type-2 dendritic cells to drive protective antitumor CD4+ T cell immunity. Cell, 177(3), 556-571.e16. (doi: 10.1016/j.cell.2019.02.005) (PMID:30955881) (PMCID:PMC6954108)
2018
Morrissey, Meghan A., Williamson, Adam P., Steinbach, Adriana M., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Kern, Nadja, Headley, Mark B. and Vale, Ronald D.
(2018)
Chimeric antigen receptors that trigger phagocytosis.
eLife, 7,
e36688.
(doi: 10.7554/eLife.36688.001)
(PMID:29862966)
(PMCID:PMC6008046)
Binnewies, M. et al. (2018) Understanding the tumor immune microenvironment (TIME) for effective therapy. Nature Medicine, 24(5), pp. 541-550. (doi: 10.1038/s41591-018-0014-x) (PMID:29686425) (PMCID:PMC5998822)
Denton, Alice E., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715 and Fearon, Douglas T.
(2018)
Stromal cells in the tumor microenvironment.
In: Owens, Benjamin M.J. and Lakins, Matthew A. (eds.)
Stromal Immunology.
Series: Advances in Experimental Medicine and Biology, 1060.
Springer, pp. 99-114.
ISBN 9783319781259
(doi: 10.1007/978-3-319-78127-3_6)
2017
Wong, Pamela T., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Tang, Shengzhuang, Mukherjee, Jhindan, Cannon, Jayme, Nip, Alyssa J., Corbin, Kaitlin, Krummel, Matthew F. and Choi, Seok Ki
(2017)
Control of an unusual photo-claisen rearrangement in coumarin caged tamoxifen through an extended spacer.
ACS Chemical Biology, 12(4),
pp. 1001-1010.
(doi: 10.1021/acschembio.6b00999)
(PMID:28191924)
(PMCID:PMC5404426)
2016
Flint, Thomas R., Janowitz, Tobias, Connell, Claire M., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Denton, Alice E., Coll, Anthony P., Jodrell, Duncan I. and Fearon, Douglas T.
(2016)
Tumor-induced IL-6 reprograms host metabolism to suppress anti-tumor immunity.
Cell Metabolism, 24(5),
pp. 672-684.
(doi: 10.1016/j.cmet.2016.10.010)
(PMID:27829137)
(PMCID:PMC5106372)
Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Broz, Miranda L., Binnewies, Mikhail, Headley, Mark B., Nelson, Amanda E., Wolf, Denise M., Kaisho, Tsuneyasu, Bogunovic, Dusan, Bhardwaj, Nina and Krummel, Matthew F.
(2016)
Critical role for CD103 + /CD141 + dendritic cells bearing CCR7 for tumor antigen trafficking and priming of T cell immunity in melanoma.
Cancer Cell, 30(2),
pp. 324-336.
(doi: 10.1016/j.ccell.2016.06.003)
(PMID:27424807)
(PMCID:PMC5374862)
Headley, Mark B., Bins, Adriaan, Nip, Alyssa, Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Looney, Mark R., Gerard, Audrey and Krummel, Matthew F.
(2016)
Visualization of immediate immune responses to pioneer metastatic cells in the lung.
Nature, 531(7595),
pp. 513-517.
(doi: 10.1038/nature16985)
(PMID:26982733)
(PMCID:PMC4892380)
Roberts, E.W. ORCID: https://orcid.org/0000-0002-8229-1715, Denton, A.E. and Fearon, D.T.
(2016)
Roles of stromal cells in the immune system.
In: Bradshaw, Ralph A. and Stahl, Philip D. (eds.)
Encyclopedia of Cell Biology.
Elsevier, pp. 616-623.
ISBN 9780123947963
(doi: 10.1016/B978-0-12-394447-4.30079-7)
2014
Denton, A.E., Roberts, E.W. ORCID: https://orcid.org/0000-0002-8229-1715, Linterman, M.A. and Fearon, D.T.
(2014)
Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America, 111(33),
pp. 12139-12144.
(doi: 10.1073/pnas.1412910111)
(PMID:25092322)
(PMCID:PMC4143042)
2013
Feig, C. et al. (2013) Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 110(50), pp. 20212-20217. (doi: 10.1073/pnas.1320318110) (PMID:24277834) (PMCID:PMC3864274)
Roberts, E. W. et al. (2013) Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia. Journal of Experimental Medicine, 210(6), pp. 1137-1151. (doi: 10.1084/jem.20122344) (PMID:23712428) (PMCID:PMC3674708)
Articles
Janas, P. P. et al. (2025) Epithelial memory after respiratory viral infection in mice results in prolonged enhancement of antigen presentation. Allergy, 80(9), pp. 2501-2518. (doi: 10.1111/all.16683) (PMID:40772364) (PMCID:PMC12444829)
Weir, Daniel, Bentley-Abbot, Calum, McCowan, Jack, Loney, Colin ORCID: https://orcid.org/0000-0002-0508-1781, Roberts, Edward
ORCID: https://orcid.org/0000-0002-8229-1715 and Hutchinson, Edward
ORCID: https://orcid.org/0000-0003-3673-9096
(2025)
Induction of tunnelling nanotube-like structures by influenza A viruses requires the onset of apoptosis.
PLoS Pathogens, 21(6),
e1013191.
(doi: 10.1371/journal.ppat.1013191)
(PMID:40472024)
(PMCID:PMC12169559)
Lau, V. W. C. et al. (2025) Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models. Nature Communications, 16(1), 2. (doi: 10.1038/s41467-024-54791-0) (PMID:39746898) (PMCID:PMC11696141)
Turnbull, M. L. et al. (2025) The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution. Nature Communications, 16, 11042. (doi: 10.1038/s41467-025-67234-1) (PMID:41398153) (PMCID:PMC12706089)
Turnbull, M. L. et al. (2024) Polygenic determinants OF H5N1 adaptation to bovine cells. bioRxiv, (doi: 10.1101/2024.11.29.626120) (PMID:PPR948676)
Hargrave, Kerrie E., Worrell, Julie C. ORCID: https://orcid.org/0000-0001-7754-1364, Pirillo, Chiara, Brennan, Euan, Masdefiol Garriga, Andreu
ORCID: https://orcid.org/0000-0002-2094-3001, Gray, Joshua I., Purnell, Thomas, Roberts, Edward W.
ORCID: https://orcid.org/0000-0002-8229-1715 and MacLeod, Megan K.L.
ORCID: https://orcid.org/0000-0003-1843-8580
(2024)
Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells.
Mucosal Immunology, 17(5),
pp. 843-857.
(doi: 10.1016/j.mucimm.2024.06.001)
(PMID:38851589)
(PMCID:PMC11464401)
Kumar, S. et al. (2024) Specialized Tfh cell subsets driving type-1 and type-21 humoral responses in lymphoid tissue. Cell Discovery, 10, 64. (doi: 10.1038/s41421-024-00681-0) (PMID:38834551) (PMCID:PMC11150427)
Bentley-Abbot, Calum, Heslop, Rhiannon, Pirillo, Chiara, Chandrasegaran, Praveena, McConnell, Gail, Roberts, Ed ORCID: https://orcid.org/0000-0002-8229-1715, Hutchinson, Edward
ORCID: https://orcid.org/0000-0003-3673-9096 and MacLeod, Annette
ORCID: https://orcid.org/0000-0002-0150-5049
(2024)
An easy to use tool for the analysis of subcellular mRNA transcript colocalisation in smFISH data.
Scientific Reports, 14,
8348.
(doi: 10.1038/s41598-024-58641-3)
(PMID:38594373)
(PMCID:PMC11004122)
Mahmood, M. et al. (2024) Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature Cancer, 5(4), pp. 659-672. (doi: 10.1038/s43018-023-00721-w) (PMID:38286828) (PMCID:PMC11056318)
Shergold, Amy, Devlin, Ryan, Young, Alex and Roberts, Ed W. ORCID: https://orcid.org/0000-0002-8229-1715
(2023)
Chemotaxis: Dendritic cells as trendsetters of the immune response.
Current Biology, 33(18),
PR957-PR959.
(doi: 10.1016/j.cub.2023.08.009)
(PMID:37751709)
Young, Alexander L., Lorimer, Tara, Al-Khalidi, Sarwah K. and Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715
(2023)
De novo priming: driver of immunotherapy responses or epiphenomenon?
Essays In Biochemistry, 67(6),
pp. 929-939.
(doi: 10.1042/EBC20220244)
(PMID:37139854)
(PMCID:PMC10539938)
Pirillo, C. et al. (2023) Cotransfer of antigen and contextual information harmonizes peripheral and lymph node conventional dendritic cell activation. Science Immunology, 8(85), eadg8249. (doi: 10.1126/sciimmunol.adg8249) (PMID:37478193) (PMCID:PMC7616026)
Cheng, Z. et al. (2023) Fluorogenic granzyme a substrates enable real‐time imaging of adaptive immune cell activity. Angewandte Chemie International Edition, 62(8), e202216142. (doi: 10.1002/anie.202216142) (PMID:36562327) (PMCID:PMC10108010)
Sims, A. et al. (2022) Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biology, 21(2), e3001941. (doi: 10.1371/journal.pbio.3001941) (PMID:36757937) (PMCID:PMC9910727)
Leslie, J. et al. (2022) CXCR2 inhibition enables NASH-HCC immunotherapy. Gut, 71(10), pp. 2093-2106. (doi: 10.1136/gutjnl-2021-326259) (PMID:35477863) (PMCID:PMC9484388)
Yi, Rulan, Chen, Emily, Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Krummel, Matthew F. and Kathrin Serwas, Nina
(2022)
Impact of protein identity on tumor-associated antigen uptake into infiltrating immune cells: A comparison of different fluorescent proteins as model antigens.
PLoS ONE, 17(8),
e0272857.
(doi: 10.1371/journal.pone.0272857)
(PMID:35976946)
(PMCID:PMC9384993)
Bravo-Blas, Alberto, Pirillo, Chiara, Shergold, Amy, Andrusaite, Anna and Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715
(2022)
Think global but act local: Tuning the dendritic cell response in cancer.
International Journal of Biochemistry and Cell Biology, 147,
106227.
(doi: 10.1016/j.biocel.2022.106227)
(PMID:35605877)
Pirillo, C. et al. (2022) Metalloproteinase inhibition reduces AML growth, prevents stem cell loss and improves chemotherapy effectiveness. Blood Advances, 6(10), pp. 3126-3141. (doi: 10.1182/bloodadvances.2021004321) (PMID:35157757) (PMCID:PMC9131921)
Devlin, Ryan and Roberts, Ed ORCID: https://orcid.org/0000-0002-8229-1715
(2022)
Building a healthy mouse model ecosystem to interrogate cancer biology.
Disease Models and Mechanisms, 15(9),
dmm049795.
(doi: 10.1242/dmm.049795)
(PMID:36098988)
(PMCID:PMC9509886)
Scott, J. I. et al. (2022) A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies. Nature Communications, 13(1), 2366. (doi: 10.1038/s41467-022-29691-w) (PMID:35501326) (PMCID:PMC9061857)
Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)
Pinkard, H. et al. (2021) Learned adaptive multiphoton illumination microscopy for large-scale immune response imaging. Nature Communications, 12(1), 1916. (doi: 10.1038/s41467-021-22246-5) (PMID:33772022) (PMCID:PMC7997974)
Binnewies, M. et al. (2019) Unleashing type-2 dendritic cells to drive protective antitumor CD4+ T cell immunity. Cell, 177(3), 556-571.e16. (doi: 10.1016/j.cell.2019.02.005) (PMID:30955881) (PMCID:PMC6954108)
Morrissey, Meghan A., Williamson, Adam P., Steinbach, Adriana M., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Kern, Nadja, Headley, Mark B. and Vale, Ronald D.
(2018)
Chimeric antigen receptors that trigger phagocytosis.
eLife, 7,
e36688.
(doi: 10.7554/eLife.36688.001)
(PMID:29862966)
(PMCID:PMC6008046)
Binnewies, M. et al. (2018) Understanding the tumor immune microenvironment (TIME) for effective therapy. Nature Medicine, 24(5), pp. 541-550. (doi: 10.1038/s41591-018-0014-x) (PMID:29686425) (PMCID:PMC5998822)
Wong, Pamela T., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Tang, Shengzhuang, Mukherjee, Jhindan, Cannon, Jayme, Nip, Alyssa J., Corbin, Kaitlin, Krummel, Matthew F. and Choi, Seok Ki
(2017)
Control of an unusual photo-claisen rearrangement in coumarin caged tamoxifen through an extended spacer.
ACS Chemical Biology, 12(4),
pp. 1001-1010.
(doi: 10.1021/acschembio.6b00999)
(PMID:28191924)
(PMCID:PMC5404426)
Flint, Thomas R., Janowitz, Tobias, Connell, Claire M., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Denton, Alice E., Coll, Anthony P., Jodrell, Duncan I. and Fearon, Douglas T.
(2016)
Tumor-induced IL-6 reprograms host metabolism to suppress anti-tumor immunity.
Cell Metabolism, 24(5),
pp. 672-684.
(doi: 10.1016/j.cmet.2016.10.010)
(PMID:27829137)
(PMCID:PMC5106372)
Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Broz, Miranda L., Binnewies, Mikhail, Headley, Mark B., Nelson, Amanda E., Wolf, Denise M., Kaisho, Tsuneyasu, Bogunovic, Dusan, Bhardwaj, Nina and Krummel, Matthew F.
(2016)
Critical role for CD103 + /CD141 + dendritic cells bearing CCR7 for tumor antigen trafficking and priming of T cell immunity in melanoma.
Cancer Cell, 30(2),
pp. 324-336.
(doi: 10.1016/j.ccell.2016.06.003)
(PMID:27424807)
(PMCID:PMC5374862)
Headley, Mark B., Bins, Adriaan, Nip, Alyssa, Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715, Looney, Mark R., Gerard, Audrey and Krummel, Matthew F.
(2016)
Visualization of immediate immune responses to pioneer metastatic cells in the lung.
Nature, 531(7595),
pp. 513-517.
(doi: 10.1038/nature16985)
(PMID:26982733)
(PMCID:PMC4892380)
Denton, A.E., Roberts, E.W. ORCID: https://orcid.org/0000-0002-8229-1715, Linterman, M.A. and Fearon, D.T.
(2014)
Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America, 111(33),
pp. 12139-12144.
(doi: 10.1073/pnas.1412910111)
(PMID:25092322)
(PMCID:PMC4143042)
Feig, C. et al. (2013) Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 110(50), pp. 20212-20217. (doi: 10.1073/pnas.1320318110) (PMID:24277834) (PMCID:PMC3864274)
Roberts, E. W. et al. (2013) Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia. Journal of Experimental Medicine, 210(6), pp. 1137-1151. (doi: 10.1084/jem.20122344) (PMID:23712428) (PMCID:PMC3674708)
Book Sections
Denton, Alice E., Roberts, Edward W. ORCID: https://orcid.org/0000-0002-8229-1715 and Fearon, Douglas T.
(2018)
Stromal cells in the tumor microenvironment.
In: Owens, Benjamin M.J. and Lakins, Matthew A. (eds.)
Stromal Immunology.
Series: Advances in Experimental Medicine and Biology, 1060.
Springer, pp. 99-114.
ISBN 9783319781259
(doi: 10.1007/978-3-319-78127-3_6)
Roberts, E.W. ORCID: https://orcid.org/0000-0002-8229-1715, Denton, A.E. and Fearon, D.T.
(2016)
Roles of stromal cells in the immune system.
In: Bradshaw, Ralph A. and Stahl, Philip D. (eds.)
Encyclopedia of Cell Biology.
Elsevier, pp. 616-623.
ISBN 9780123947963
(doi: 10.1016/B978-0-12-394447-4.30079-7)
Conference or Workshop Item
Leung, E. Y.l. et al. (2024) Chemokine CCL21 Induces an Immunotolerant Tumour Microenvironment Leading to Poorer Survival in Ovarian Cancer. ESGO 2024 Congress, Barcelona, Spain, 7-10 March 2024. (doi: 10.1136/ijgc-2024-esgo.985)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Investigating the tumour microenvironment of high risk localised prostate cancer to identify actionable pathways involved in cancer progression
Prostate Cancer UK
2024 - 2029
Research datasets
2025
Turnbull, M. , Zakaria, M. K. , Upfold, N. , Bakshi, S., Magill, C., DAS, U. R., Clarke, A. , Mojsiejczuk, L., Herder, V. , Dee, K., Liu, N., Folwarczna, M., Ilia, G., Schultz, V. , Chen, H., Devlin, R., McCowan, J., Young, A., Po, W. W., Smollett, K. , Yaseen, H., Ross, R., Bhide, A., van Kekem, B., Fouchier, R., da Silva Felipe, A., Iqbal, M., Roberts, E. , Hughes, J. , Werling, D., Murcia, P. and Palmarini, M. (2025) The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution. [Data Collection]
2022
Sims, A., Burgess Tornaletti, L., Jasim, S., Pirillo, C., Devlin, R., Hirst, J., Loney, C. , Wojtus, J., Sloan, E., Thorley, L., Boutell, C. , Roberts, E. and Hutchinson, E. (2022) Superinfection exclusion creates spatially distinct influenza virus populations. [Data Collection]