Dr Monica Tsimbouri
- Research Technologist (Molecular Biosciences)
- Affiliate - Life Sciences (School of Molecular Biosciences)
telephone:
01413307555
email:
Penelope.Tsimbouri@glasgow.ac.uk
room 492,, Institute of MC&SB, Advanced Research Centre, (ARC), 11 Chapel Lane,, Glasgow,, G11 6EW
https://orcid.org/0000-0001-5124-7458Research interests
Publications
2023
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
2022
Xiao, Y., Donnelly, H., Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367) (PMID:35937570) (PMCID:PMC9352550)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
2021
Kennedy, J. W., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P. S., Meek, D. R. M., Goodyear, C. S. and Dalby, M. J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. Scientific Reports, 11, 22741. (doi: 10.1038/s41598-021-02139-9)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
2020
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
2018
Waddell, S. J., de Andrés, M. C., Tsimbouri, P. M. , Alakpa, E. V., Cusack, M., Dalby, M. J. and Oreffo, R. O.C. (2018) Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells. Journal of Tissue Engineering, 9, p. 2041731418794007. (doi: 10.1177/2041731418794007) (PMID:30202512) (PMCID:PMC6124183)
Robertson, S. N. et al. (2018) Control of cell behaviour through nanovibrational stimulation: nanokicking. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 376(2120), 20170290. (doi: 10.1098/rsta.2017.0290) (PMID:29661978) (PMCID:PMC5915650)
Orapiriyakul, W., Young, P. S., Damiati, L. and Tsimbouri, P. M. (2018) Antibacterial surface modification of titanium implants in orthopaedics. Journal of Tissue Engineering, 9, pp. 1-16. (doi: 10.1177/2041731418789838) (PMID:30083308) (PMCID:PMC6071164)
Allan, C., Ker, A., Smith, C.-A. , Tsimbouri, P. , Borsoi, J., O'Neill, S., Gadegaard, N. , Dalby, M. J. and Meek, D. (2018) Osteoblast response to disordered nanotopography. Journal of Tissue Engineering, 9, pp. 1-7. (doi: 10.1177/2041731418784098) (PMID:30034770) (PMCID:PMC6048666)
AlQarni, S. et al. (2018) Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2. Oncogene, 37, pp. 3998-4012. (doi: 10.1038/s41388-018-0147-x) (PMID:29691476) (PMCID:PMC6054874)
Damiati, L., Eales, M. G., Nobbs, A. H., Su, B., Tsimbouri, P. , Salmeron-Sanchez, M. and Dalby, M. J. (2018) Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants. Journal of Tissue Engineering, 9, pp. 1-16. (doi: 10.1177/2041731418790694) (PMID:30116518)
2017
Fraioli, R. et al. (2017) Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports, 7, 16363. (doi: 10.1038/s41598-017-16385-3) (PMID:29180787) (PMCID:PMC5703844)
Thomson, S. E., Charalambous, C., Smith, C.-A. , Tsimbouri, P. M. , Déjardin, T., Kingham, P. J., Hart, A. M. and Riehle, M. O. (2017) Microtopographical cues promote peripheral nerve regeneration via transient mTORC2 activation. Acta Biomaterialia, 60, pp. 220-231. (doi: 10.1016/j.actbio.2017.07.031) (PMID:28754648) (PMCID:PMC5593812)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
Anderson, H., Llopis-Hernandez, V. , Sweeten, P., Donnelly, H., Gurden, R., Orapiriyakul, W., Salmeron-Sanchez, M. , Dalby, M.J. and Tsimbouri, M.P. (2017) Nanoscale surface cues and cell behaviour. In: Hashmi, S. (ed.) Reference Module in Materials Science and Materials Engineering. Elsevier. ISBN 9780128035818 (doi: 10.1016/B978-0-12-803581-8.10226-7)
2016
Tsimbouri, P.M. , Fisher, L., Holloway, N., Sjostrom, T., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates. Scientific Reports, 6, 36857. (doi: 10.1038/srep36857) (PMID:27857168) (PMCID:PMC5114696)
Tsimbouri, P.M. , Holloway, N., Fisher, L., Sjostrom, T., Nobbs, A.H., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and Bactericidal Surfaces from Hydrothermal Titania Nanowires on Titanium Substrates. The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016.
Young, P.S., Greer, A.I.M. , Tsimbouri, P.M. , Meek, R.M.D., Gadegaard, N. and Dalby, M.J. (2016) Precision-Engineered Nanotopographical Surfaces to Control Osteoclast Differentiation. In: The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016,
Llopis-Hernández, V. , Cantini, M. , González-García, C., Cheng, Z. A., Yang, J., Tsimbouri, P. M. , García, A. J., Dalby, M. J. and Salmerón-Sánchez, M. (2016) Material-driven fibronectin assembly for high-efficiency presentation of growth factors. Science Advances, 2(8), e1600188. (doi: 10.1126/sciadv.1600188) (PMID:27574702) (PMCID:PMC5001810)
Silverwood, R. K. et al. (2016) Analysis of osteoclastogenesis/osteoblastogenesis on nanotopographical titania surfaces. Advanced Healthcare Materials, 5(8), pp. 947-955. (doi: 10.1002/adhm.201500664) (PMID:26890261)
Adekanmbi, I., Ferguson, L., Tsimbouri, P.M. , Riehle, M. , Kubba, H. and Tanner, K.E. (2016) Evaluation of Cell Viability of Biodegradable AZ31 Mg Alloy for Use in Paediatric Tracheal Stent after Long Term In Vitro Corrosion. In: 10th World Biomaterials Congress, Montreal, Canada, 17-22 May 2016, (doi: 10.3389/conf.FBIOE.2016.01.02513)
2015
Tsimbouri, P. (2015) Adult stem cell responses to nanostimuli. Journal of Functional Biomaterials, 6(3), pp. 598-622. (doi: 10.3390/jfb6030598) (PMID:26193326) (PMCID:PMC4598673)
Pemberton, G. D., Childs, P., Reid, S., Nikukar, H., Tsimbouri, M. , Gadegaard, N. , Curtis, A. S. and Dalby, M. J. (2015) Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking. Nanomedicine, 10(4), pp. 547-560. (doi: 10.2217/nnm.14.134) (PMID:25723089)
Tsimbouri, P. M. , McNamara, L. E., Alakpa, E. V., Dalby, M. J. and Turner, L.-A. (2015) Cell material interactions. In: van Blitterswijk, C. A. and de Boer, J. (eds.) Tissue Engineering. Elsevier, pp. 217-251. ISBN 9780124202108 (doi: 10.1016/B978-0-12-420145-3.00007-9)
Young, P.S., Tsimbouri, P.M. , Gadegaard, N. , Meek, R.M.D. and Dalby, M.J. (2015) Osteoclastogenesis/osteoblastogenesis using human bone marrow-derived cocultures on nanotopographical polymer surfaces. Nanomedicine, 10(6), pp. 949-957. (doi: 10.2217/nnm.14.146) (PMID:25867859)
2014
Thomson, S. E., Déjardin, T., Tsimbouri, M. P. , Hart, A. M. and Riehle, M. O. (2014) Combinational approaches to improve outcomes following peripheral nerve repair. Journal of Plastic, Reconstructive and Aesthetic Surgery, 67(10), p. 1465. (doi: 10.1016/j.bjps.2014.08.032)
Curtis, A. S. and Tsimbouri, P. M. (2014) Epigenesis: roles of nanotopography, nanoforces and nanovibration. Expert Review of Medical Devices, 11(4), pp. 417-423. (doi: 10.1586/17434440.2014.916205)
McMurray, R. J., Dalby, M. and Tsimbouri, P. M. (2014) Using biomaterials to study stem cell mechanotransduction, growth and differentiation. Journal of Tissue Engineering and Regenerative Medicine, 9(5), pp. 528-539. (doi: 10.1002/term.1957) (PMID:25370612)
Silverwood, R.K., Fairhurst, P., Tsimbouri, P. , Sjostrom, T., Young, P., Su, B., Meek, R.M.D. and Dalby, M. (2014) Analysis of Osteoclastogenesis/Osteoblastogenesis Using Human Bone Marrow Derived Co-Cultures on Nanotopographical Titania Surfaces. In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, UK, 28 Mar 2014,
Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)
McNamara, L. E., Dalby, M. J. and Tsimbouri, M. P. (2014) The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography. Methods in Cell Biology, 119, pp. 293-309. (doi: 10.1016/B978-0-12-416742-1.00015-9) (PMID:24439291)
2013
Seras-Franzoso, J., Peebo, K., Corchero, J.L., Tsimbouri, P.M. , Unzueta, U., Rinas, U., Dalby, M.J. , Vazquez, E., García-Fruitós, E. and Villaverde, A. (2013) A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs. Nanomedicine, 8(10), pp. 1587-1599. (doi: 10.2217/nnm.12.188)
Herd, J.M., Joseph, J., McGarvey, M., Tsimbouri, P. , Bennett, A., Meek, R.M.D. and Morrison, A. (2013) Intra-Operative Cell Salvage in Revision Hip Surgery. In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, 2013,
Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. , Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2013) Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction. ACS Nano, 7(3), pp. 2758-2767. (doi: 10.1021/nn400202j)
Wiejak, J., Tsimbouri, P. M. , Herzyk, P. , Dalby, M. J. , Hamilton, G. and Yarwood, S. J. (2013) Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves. Biomaterials, 34(8), pp. 1967-1979. (doi: 10.1016/j.biomaterials.2012.11.036) (PMID:23245923) (PMCID:PMC3543902)
Tsimbouri, P. M. , Murawski, K., Hamilton, G., Herzyk, P. , Oreffo, R. O.C., Gadegaard, N. and Dalby, M. J. (2013) A genomics approach in determining nanotopographical effects on MSC phenotype. Biomaterials, 34(9), pp. 2177-2184. (doi: 10.1016/j.biomaterials.2012.12.019) (PMID:23312853) (PMCID:PMC3573234)
Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)
2012
Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)
Dalby, M.J. , Macintyre, A., Roberts, J.N. , Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanosubstrates to illustrate differential adhesion mechanisms to fibronectin and vitronectin. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L..L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) 3D patterned agarose hydrogels for investigation of precursor cells in differentiation and chemoattraction. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanoporous titanium substrates for osteogenesis. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Research Highlights. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
2011
McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)
Kingham, E.J., Tsimbouri, P.M. , Gadegaard, N. , Dalby, M.J. and Oreffo, R.O.C. (2011) Nanotopography induced osteogenic differentiation of human stem cells. Bone, 48(Sup. 2), S108-S109. (doi: 10.1016/j.bone.2011.03.177)
Hannigan, A., Qureshi, A.M., Nixon, C., Tsimbouri, P.M. , Jones, S., Philbey, A.W. and Wilson, J.B. (2011) Lymphocyte deficiency limits Epstein-Barr virus latent membrane protein 1 induced chronic inflammation and carcinogenic pathology in vivo. Molecular Cancer, 10(11), pp. 1-20. (doi: 10.1186/1476-4598-10-11)
Khokhar, A.Z., Tsimbouri, P.M. , Dalby, M.J. and Gadegaard, N. (2011) Development of ultra-hard stamps for titanium patterning. In: 37th International Conference on Micro and Nano Engineering: MNE 2011, Berlin, 19 - 23 September 2011,
McNamara, L.E., McMurray, R.J., Dalby, M.J. and Tsimbouri, P.M. (2011) Surfaces and Cell Behavior. Comprehensive Biomaterials, 4(409), pp. 115-126. (doi: 10.1016/B978-0-08-055294-1.00010-6)
Nokhbatolfoghahai, M., Tsimbouri, P.M. , Wilson, J.B. and Downie, J.R. (2011) Evolutionary analysis of genes involved in cement gland development in anurans. Iranian Journal of Science and Technology, A3,
Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.
Tsimbouri, P. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2011) Effects of nanotopography on cell adhesion, morphology and differentiation. European Cells and Materials, 22(S2), p. 14.
2010
McMurray, R.J., Gadegaard, N. , Dalby, M.J. , Tsimbouri, P.M. , Maclaine, S., Meek, D., McNamara, L.E., Child, H. and Berry, C.C. (2010) Research highlights. Nanomedicine, 5(10), pp. 1495-1499. (doi: 10.2217/nnm.10.119)
Repellin, C.E., Tsimbouri, P.M. , Philbey, A.W. and Wilson, J.B. (2010) Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus. PLoS ONE, 5(2), e9092. (doi: 10.1371/journal.pone.0009092)
2009
Rossi, L., Riehle, M.O. , McNamara, L.E., Burchmore, R. , Dalby, M.J. , McMurray, R.J., Gadegaard, N. , Ahmed, S. and Tsimbouri, P.M. (2009) Research highlights. Nanomedicine, 4(6), pp. 613-617. (doi: 10.2217/nnm.09.46)
2008
McLean, A., Tsimbouri, P. and Wilson, J.B. (2008) Massive Overexpression of Chitnase3-like 4 (YM2), CD30 and Immunoglobulin in LMP1 Induced Inflammation Associated Carcinogenesis. 13th International EBV Symposium, Guangzgou, China, 7-10 Nov 2008.
Tsimbouri, P. , Chiou, Y.-C. and Wilson, J.B. (2008) EBERs the Small Viral Non-coding RNAs are Tumourigenic and Disturb the Interferon Response in Vivo. Beatson International Cancer Conference Cell Growth and Metabolism, Glasgow, UK, 15-18 Jun 2008.
Tsimbouri, P. , Al-Sheikh, Y., Drotar, M. E., Cushley, W. and Wilson, J.B. (2008) Epstein-Barr virus nuclear antigen-1 renders lymphocytes responsive to IL-2 but not IL-15 for survival. Journal of General Virology, 89(11), pp. 2821-2832. (doi: 10.1099/vir.0.83296-0)
2007
Chiou, Y.-C., Tsimbouri, P. and Wilson, J.B. (2007) EBER1 – a Small Viral Non-coding RNA is Tumourigenic and Disturbs the Interferon Response in Vivo. Beatson International Cancer Conference, Glasgow, UK, 16-20 Jun 2007.
Charalambous, C.T., Hannigan, A., Tsimbouri, P. , McPhee, G.M. and Wilson, J.B. (2007) Latent membrane protein 1-induced EGFR signalling is negatively regulated by TGF prior to neoplasia. Carcinogenesis, 28(8), pp. 1839-1848. (doi: 10.1093/carcin/bgm055)
2006
Tsimbouri, P. , Al-Sheikh, Y., Mclean, A., Drotar, M. and Wilson, J. B. (2006) An Evaluation of the Contribution of EBNA1 Expression to Transgenic Mouse Lymphomagenesis. 12th International EBV Symposium, Boston, MA, USA, 08-12 Jul 2006.
2005
Tsimbouri, P.M. and Wilson, J.B. (2005) A viral oncogene which induces B-cells to survive in response to IL-2. Experimental Hematology, 33(S7), p. 112. (doi: 10.1016/j.exphem.2005.05.017)
2004
Tsimbouri, P. , Drotar, M., Hill, E. and Wilson, J.B. (2004) EBNA1 Induces B-cells to Respond to IL-2 Survival Signals. 11th International EBV Symposium, Regensberg, Germany, 20-25 Sep 2004.
2003
Drotar, M.E., Silva, S., Barone, E., Campbell, D., Tsimbouri, P. , Jurvansu, J., Bhatia, P., Klein, G. and Wilson, J.B. (2003) Epstein-Barr virus nuclear antigen-1 and Myc cooperate in lymphomagenesis. International Journal of Cancer, 106, pp. 388-395. (doi: 10.1002/ijc.11224) (PMID:12845679)
2002
Tsimbouri, P. and Wilson, J.B. (2002) The Action of EBNA1 as an Oncogene in Vivo. 10th International Symposium on Epstein-Barr Virus and Associated Malignant Diseases, Cairns, Australia, 16-21 Jul 2002.
Tsimbouri, P. , Drotar, M.E., Coy, J.L. and Wilson, J.B. (2002) bcl-x(L) and RAG genes are induced and the response to IL-2 enhanced in E mu EBNA-1 transgenic mouse lymphocytes. Oncogene, 21, pp. 5182-5187. (doi: 10.1038/sj.onc.1205490)
2001
Tsimbouri, P. , O'Donnell, M.A. and Wilson, J.B. (2001) Selection and enrichment of B cells from lymphoid tissues. In: Wilson, J.B.,. and May, G.H.W. (eds.) Epstein-Barr Virus Protocols. Series: Methods in Molecular Biology (174). The Humana Press Inc.: Totowa, N.J., pp. 411-421. ISBN 9780896036901 (doi: 10.1385/1-59259-227-9:411)
2000
Tsimbouri, P. , Cushley, W. and Wilson, J.B. (2000) EBNA1 Mechanism of Action as an Oncogene. 9th Biennial Conference of the International Assoication for Research on Epstein-Barr Virus, New Haven, CT, USA, 22-27 Jun 2000.
Tsimbouri, P. , Cushley, W. and Wilson, J.B. (2000) EBNA-1 Action as an Oncogene. 10th TENOVUS Scotland Symposium: Gene Expression and Disease, Glasgow, UK, 10-12 Apr 2000.
Articles
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Xiao, Y., Donnelly, H., Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367) (PMID:35937570) (PMCID:PMC9352550)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
Kennedy, J. W., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P. S., Meek, D. R. M., Goodyear, C. S. and Dalby, M. J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. Scientific Reports, 11, 22741. (doi: 10.1038/s41598-021-02139-9)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
Waddell, S. J., de Andrés, M. C., Tsimbouri, P. M. , Alakpa, E. V., Cusack, M., Dalby, M. J. and Oreffo, R. O.C. (2018) Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells. Journal of Tissue Engineering, 9, p. 2041731418794007. (doi: 10.1177/2041731418794007) (PMID:30202512) (PMCID:PMC6124183)
Robertson, S. N. et al. (2018) Control of cell behaviour through nanovibrational stimulation: nanokicking. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 376(2120), 20170290. (doi: 10.1098/rsta.2017.0290) (PMID:29661978) (PMCID:PMC5915650)
Orapiriyakul, W., Young, P. S., Damiati, L. and Tsimbouri, P. M. (2018) Antibacterial surface modification of titanium implants in orthopaedics. Journal of Tissue Engineering, 9, pp. 1-16. (doi: 10.1177/2041731418789838) (PMID:30083308) (PMCID:PMC6071164)
Allan, C., Ker, A., Smith, C.-A. , Tsimbouri, P. , Borsoi, J., O'Neill, S., Gadegaard, N. , Dalby, M. J. and Meek, D. (2018) Osteoblast response to disordered nanotopography. Journal of Tissue Engineering, 9, pp. 1-7. (doi: 10.1177/2041731418784098) (PMID:30034770) (PMCID:PMC6048666)
AlQarni, S. et al. (2018) Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2. Oncogene, 37, pp. 3998-4012. (doi: 10.1038/s41388-018-0147-x) (PMID:29691476) (PMCID:PMC6054874)
Damiati, L., Eales, M. G., Nobbs, A. H., Su, B., Tsimbouri, P. , Salmeron-Sanchez, M. and Dalby, M. J. (2018) Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants. Journal of Tissue Engineering, 9, pp. 1-16. (doi: 10.1177/2041731418790694) (PMID:30116518)
Fraioli, R. et al. (2017) Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports, 7, 16363. (doi: 10.1038/s41598-017-16385-3) (PMID:29180787) (PMCID:PMC5703844)
Thomson, S. E., Charalambous, C., Smith, C.-A. , Tsimbouri, P. M. , Déjardin, T., Kingham, P. J., Hart, A. M. and Riehle, M. O. (2017) Microtopographical cues promote peripheral nerve regeneration via transient mTORC2 activation. Acta Biomaterialia, 60, pp. 220-231. (doi: 10.1016/j.actbio.2017.07.031) (PMID:28754648) (PMCID:PMC5593812)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
Tsimbouri, P.M. , Fisher, L., Holloway, N., Sjostrom, T., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates. Scientific Reports, 6, 36857. (doi: 10.1038/srep36857) (PMID:27857168) (PMCID:PMC5114696)
Llopis-Hernández, V. , Cantini, M. , González-García, C., Cheng, Z. A., Yang, J., Tsimbouri, P. M. , García, A. J., Dalby, M. J. and Salmerón-Sánchez, M. (2016) Material-driven fibronectin assembly for high-efficiency presentation of growth factors. Science Advances, 2(8), e1600188. (doi: 10.1126/sciadv.1600188) (PMID:27574702) (PMCID:PMC5001810)
Silverwood, R. K. et al. (2016) Analysis of osteoclastogenesis/osteoblastogenesis on nanotopographical titania surfaces. Advanced Healthcare Materials, 5(8), pp. 947-955. (doi: 10.1002/adhm.201500664) (PMID:26890261)
Tsimbouri, P. (2015) Adult stem cell responses to nanostimuli. Journal of Functional Biomaterials, 6(3), pp. 598-622. (doi: 10.3390/jfb6030598) (PMID:26193326) (PMCID:PMC4598673)
Pemberton, G. D., Childs, P., Reid, S., Nikukar, H., Tsimbouri, M. , Gadegaard, N. , Curtis, A. S. and Dalby, M. J. (2015) Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking. Nanomedicine, 10(4), pp. 547-560. (doi: 10.2217/nnm.14.134) (PMID:25723089)
Young, P.S., Tsimbouri, P.M. , Gadegaard, N. , Meek, R.M.D. and Dalby, M.J. (2015) Osteoclastogenesis/osteoblastogenesis using human bone marrow-derived cocultures on nanotopographical polymer surfaces. Nanomedicine, 10(6), pp. 949-957. (doi: 10.2217/nnm.14.146) (PMID:25867859)
Thomson, S. E., Déjardin, T., Tsimbouri, M. P. , Hart, A. M. and Riehle, M. O. (2014) Combinational approaches to improve outcomes following peripheral nerve repair. Journal of Plastic, Reconstructive and Aesthetic Surgery, 67(10), p. 1465. (doi: 10.1016/j.bjps.2014.08.032)
Curtis, A. S. and Tsimbouri, P. M. (2014) Epigenesis: roles of nanotopography, nanoforces and nanovibration. Expert Review of Medical Devices, 11(4), pp. 417-423. (doi: 10.1586/17434440.2014.916205)
McMurray, R. J., Dalby, M. and Tsimbouri, P. M. (2014) Using biomaterials to study stem cell mechanotransduction, growth and differentiation. Journal of Tissue Engineering and Regenerative Medicine, 9(5), pp. 528-539. (doi: 10.1002/term.1957) (PMID:25370612)
Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)
McNamara, L. E., Dalby, M. J. and Tsimbouri, M. P. (2014) The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography. Methods in Cell Biology, 119, pp. 293-309. (doi: 10.1016/B978-0-12-416742-1.00015-9) (PMID:24439291)
Seras-Franzoso, J., Peebo, K., Corchero, J.L., Tsimbouri, P.M. , Unzueta, U., Rinas, U., Dalby, M.J. , Vazquez, E., García-Fruitós, E. and Villaverde, A. (2013) A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs. Nanomedicine, 8(10), pp. 1587-1599. (doi: 10.2217/nnm.12.188)
Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. , Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2013) Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction. ACS Nano, 7(3), pp. 2758-2767. (doi: 10.1021/nn400202j)
Wiejak, J., Tsimbouri, P. M. , Herzyk, P. , Dalby, M. J. , Hamilton, G. and Yarwood, S. J. (2013) Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves. Biomaterials, 34(8), pp. 1967-1979. (doi: 10.1016/j.biomaterials.2012.11.036) (PMID:23245923) (PMCID:PMC3543902)
Tsimbouri, P. M. , Murawski, K., Hamilton, G., Herzyk, P. , Oreffo, R. O.C., Gadegaard, N. and Dalby, M. J. (2013) A genomics approach in determining nanotopographical effects on MSC phenotype. Biomaterials, 34(9), pp. 2177-2184. (doi: 10.1016/j.biomaterials.2012.12.019) (PMID:23312853) (PMCID:PMC3573234)
Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)
Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)
Dalby, M.J. , Macintyre, A., Roberts, J.N. , Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanosubstrates to illustrate differential adhesion mechanisms to fibronectin and vitronectin. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L..L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) 3D patterned agarose hydrogels for investigation of precursor cells in differentiation and chemoattraction. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanoporous titanium substrates for osteogenesis. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Research Highlights. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)
Kingham, E.J., Tsimbouri, P.M. , Gadegaard, N. , Dalby, M.J. and Oreffo, R.O.C. (2011) Nanotopography induced osteogenic differentiation of human stem cells. Bone, 48(Sup. 2), S108-S109. (doi: 10.1016/j.bone.2011.03.177)
Hannigan, A., Qureshi, A.M., Nixon, C., Tsimbouri, P.M. , Jones, S., Philbey, A.W. and Wilson, J.B. (2011) Lymphocyte deficiency limits Epstein-Barr virus latent membrane protein 1 induced chronic inflammation and carcinogenic pathology in vivo. Molecular Cancer, 10(11), pp. 1-20. (doi: 10.1186/1476-4598-10-11)
McNamara, L.E., McMurray, R.J., Dalby, M.J. and Tsimbouri, P.M. (2011) Surfaces and Cell Behavior. Comprehensive Biomaterials, 4(409), pp. 115-126. (doi: 10.1016/B978-0-08-055294-1.00010-6)
Nokhbatolfoghahai, M., Tsimbouri, P.M. , Wilson, J.B. and Downie, J.R. (2011) Evolutionary analysis of genes involved in cement gland development in anurans. Iranian Journal of Science and Technology, A3,
Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.
Tsimbouri, P. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2011) Effects of nanotopography on cell adhesion, morphology and differentiation. European Cells and Materials, 22(S2), p. 14.
McMurray, R.J., Gadegaard, N. , Dalby, M.J. , Tsimbouri, P.M. , Maclaine, S., Meek, D., McNamara, L.E., Child, H. and Berry, C.C. (2010) Research highlights. Nanomedicine, 5(10), pp. 1495-1499. (doi: 10.2217/nnm.10.119)
Repellin, C.E., Tsimbouri, P.M. , Philbey, A.W. and Wilson, J.B. (2010) Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus. PLoS ONE, 5(2), e9092. (doi: 10.1371/journal.pone.0009092)
Rossi, L., Riehle, M.O. , McNamara, L.E., Burchmore, R. , Dalby, M.J. , McMurray, R.J., Gadegaard, N. , Ahmed, S. and Tsimbouri, P.M. (2009) Research highlights. Nanomedicine, 4(6), pp. 613-617. (doi: 10.2217/nnm.09.46)
Tsimbouri, P. , Al-Sheikh, Y., Drotar, M. E., Cushley, W. and Wilson, J.B. (2008) Epstein-Barr virus nuclear antigen-1 renders lymphocytes responsive to IL-2 but not IL-15 for survival. Journal of General Virology, 89(11), pp. 2821-2832. (doi: 10.1099/vir.0.83296-0)
Charalambous, C.T., Hannigan, A., Tsimbouri, P. , McPhee, G.M. and Wilson, J.B. (2007) Latent membrane protein 1-induced EGFR signalling is negatively regulated by TGF prior to neoplasia. Carcinogenesis, 28(8), pp. 1839-1848. (doi: 10.1093/carcin/bgm055)
Tsimbouri, P.M. and Wilson, J.B. (2005) A viral oncogene which induces B-cells to survive in response to IL-2. Experimental Hematology, 33(S7), p. 112. (doi: 10.1016/j.exphem.2005.05.017)
Drotar, M.E., Silva, S., Barone, E., Campbell, D., Tsimbouri, P. , Jurvansu, J., Bhatia, P., Klein, G. and Wilson, J.B. (2003) Epstein-Barr virus nuclear antigen-1 and Myc cooperate in lymphomagenesis. International Journal of Cancer, 106, pp. 388-395. (doi: 10.1002/ijc.11224) (PMID:12845679)
Tsimbouri, P. , Drotar, M.E., Coy, J.L. and Wilson, J.B. (2002) bcl-x(L) and RAG genes are induced and the response to IL-2 enhanced in E mu EBNA-1 transgenic mouse lymphocytes. Oncogene, 21, pp. 5182-5187. (doi: 10.1038/sj.onc.1205490)
Book Sections
Anderson, H., Llopis-Hernandez, V. , Sweeten, P., Donnelly, H., Gurden, R., Orapiriyakul, W., Salmeron-Sanchez, M. , Dalby, M.J. and Tsimbouri, M.P. (2017) Nanoscale surface cues and cell behaviour. In: Hashmi, S. (ed.) Reference Module in Materials Science and Materials Engineering. Elsevier. ISBN 9780128035818 (doi: 10.1016/B978-0-12-803581-8.10226-7)
Tsimbouri, P. M. , McNamara, L. E., Alakpa, E. V., Dalby, M. J. and Turner, L.-A. (2015) Cell material interactions. In: van Blitterswijk, C. A. and de Boer, J. (eds.) Tissue Engineering. Elsevier, pp. 217-251. ISBN 9780124202108 (doi: 10.1016/B978-0-12-420145-3.00007-9)
Tsimbouri, P. , O'Donnell, M.A. and Wilson, J.B. (2001) Selection and enrichment of B cells from lymphoid tissues. In: Wilson, J.B.,. and May, G.H.W. (eds.) Epstein-Barr Virus Protocols. Series: Methods in Molecular Biology (174). The Humana Press Inc.: Totowa, N.J., pp. 411-421. ISBN 9780896036901 (doi: 10.1385/1-59259-227-9:411)
Conference or Workshop Item
Tsimbouri, P.M. , Holloway, N., Fisher, L., Sjostrom, T., Nobbs, A.H., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and Bactericidal Surfaces from Hydrothermal Titania Nanowires on Titanium Substrates. The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016.
McLean, A., Tsimbouri, P. and Wilson, J.B. (2008) Massive Overexpression of Chitnase3-like 4 (YM2), CD30 and Immunoglobulin in LMP1 Induced Inflammation Associated Carcinogenesis. 13th International EBV Symposium, Guangzgou, China, 7-10 Nov 2008.
Tsimbouri, P. , Chiou, Y.-C. and Wilson, J.B. (2008) EBERs the Small Viral Non-coding RNAs are Tumourigenic and Disturb the Interferon Response in Vivo. Beatson International Cancer Conference Cell Growth and Metabolism, Glasgow, UK, 15-18 Jun 2008.
Chiou, Y.-C., Tsimbouri, P. and Wilson, J.B. (2007) EBER1 – a Small Viral Non-coding RNA is Tumourigenic and Disturbs the Interferon Response in Vivo. Beatson International Cancer Conference, Glasgow, UK, 16-20 Jun 2007.
Tsimbouri, P. , Al-Sheikh, Y., Mclean, A., Drotar, M. and Wilson, J. B. (2006) An Evaluation of the Contribution of EBNA1 Expression to Transgenic Mouse Lymphomagenesis. 12th International EBV Symposium, Boston, MA, USA, 08-12 Jul 2006.
Tsimbouri, P. , Drotar, M., Hill, E. and Wilson, J.B. (2004) EBNA1 Induces B-cells to Respond to IL-2 Survival Signals. 11th International EBV Symposium, Regensberg, Germany, 20-25 Sep 2004.
Tsimbouri, P. and Wilson, J.B. (2002) The Action of EBNA1 as an Oncogene in Vivo. 10th International Symposium on Epstein-Barr Virus and Associated Malignant Diseases, Cairns, Australia, 16-21 Jul 2002.
Tsimbouri, P. , Cushley, W. and Wilson, J.B. (2000) EBNA1 Mechanism of Action as an Oncogene. 9th Biennial Conference of the International Assoication for Research on Epstein-Barr Virus, New Haven, CT, USA, 22-27 Jun 2000.
Tsimbouri, P. , Cushley, W. and Wilson, J.B. (2000) EBNA-1 Action as an Oncogene. 10th TENOVUS Scotland Symposium: Gene Expression and Disease, Glasgow, UK, 10-12 Apr 2000.
Conference Proceedings
Young, P.S., Greer, A.I.M. , Tsimbouri, P.M. , Meek, R.M.D., Gadegaard, N. and Dalby, M.J. (2016) Precision-Engineered Nanotopographical Surfaces to Control Osteoclast Differentiation. In: The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016,
Adekanmbi, I., Ferguson, L., Tsimbouri, P.M. , Riehle, M. , Kubba, H. and Tanner, K.E. (2016) Evaluation of Cell Viability of Biodegradable AZ31 Mg Alloy for Use in Paediatric Tracheal Stent after Long Term In Vitro Corrosion. In: 10th World Biomaterials Congress, Montreal, Canada, 17-22 May 2016, (doi: 10.3389/conf.FBIOE.2016.01.02513)
Silverwood, R.K., Fairhurst, P., Tsimbouri, P. , Sjostrom, T., Young, P., Su, B., Meek, R.M.D. and Dalby, M. (2014) Analysis of Osteoclastogenesis/Osteoblastogenesis Using Human Bone Marrow Derived Co-Cultures on Nanotopographical Titania Surfaces. In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, UK, 28 Mar 2014,
Herd, J.M., Joseph, J., McGarvey, M., Tsimbouri, P. , Bennett, A., Meek, R.M.D. and Morrison, A. (2013) Intra-Operative Cell Salvage in Revision Hip Surgery. In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, 2013,
Khokhar, A.Z., Tsimbouri, P.M. , Dalby, M.J. and Gadegaard, N. (2011) Development of ultra-hard stamps for titanium patterning. In: 37th International Conference on Micro and Nano Engineering: MNE 2011, Berlin, 19 - 23 September 2011,
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Development of NanoKick Bioreactor
Biotechnology and Biological Sciences Research Council
2016 - 2017
- Using nanokicking to discover and exploit differences in mechanical response between normal and cancerous cells
Bone Cancer Research Trust
2015 - 2015
- Manipulation of primary cancer cells by nanotopography
Tenovus Scotland
2013 - 2013
- Manipulation of cancer cells by nanotopography: strategies to control migration, proliferation and apoptosis (ISSF Catalyst Fund)
Wellcome Trust
2011 - 2014
Research datasets
2021
Kennedy, J., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P., Reid, S., Young, P., Meek, D., Goodyear, C. and Dalby, M. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. [Data Collection]
Damiati, L. , Tsimbouri, M. , Eales, M., Jayawarna, V., Xiao, Y., Li, P. , Burgess, K., Wells, J., Meek, R.M. D., Oreffo, R. O. C., Nobbs, A., Ramage, G. , Salmeron-Sanchez, M. and Dalby, M. (2021) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. [Data Collection]
Kennedy, J., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P., Meek, D. R. M., Goodyear, C. S. and Dalby, M. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. [Data Collection]
2020
Orapiriyakul, W., Tsimbouri, M. , Childs, P., Campsie, P., Wells, J., Fernandez-Yague, M. A., Burgess, K., Tanner, E., Tassieri, M. , Meek, D., Vassalli, M. , Biggs, M. J.P., Salmeron-Sanchez, M. , Oreffo, R. O. C., Reid, S. and Dalby, M. (2020) Nanovibrational Stimulation of Mesenchymal Stem Cells Induces Therapeutic Reactive Oxygen Species and Inflammation for Three- Dimensional Bone Tissue Engineering. [Data Collection]
Hodgkinson, T., Tsimbouri, M. , Llopis-Hernandez, V. , Campsie, P., Scurr, D., Childs, P., Phillips, D. , Donnelly, S., Wells, J., Salmeron-Sanchez, M. , Burgess, K., Alexander, M., Vassalli, M. , Oreffo, R., Reid, S., France, D. and Dalby, M. (2020) Nanovibrational mesenchymal stem cell stimulation allows detection of highly osteo-specific bioactive metabolites that can be modified for enhanced potency. [Data Collection]
2017
Tsimbouri, P. , Childs, P., Pemberton, G. D., Yang, J., Jayawarna, V., Orapiriyakul, W., Burgess, K., Gonzalez-Garcia, C., Blackburn, G., Thomas, D., Giraldo, C. V., Biggs, M. J. P., Curtis, A., Salmerón-Sanchez, M., Reid, S. and Dalby, M. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells via a nanovibrational bioreactor. [Data Collection]
2016
Silverwood, R. K., Fairhurst, P. G., Sjöström, T., Welsh, F., Sun, Y., Li, G., Yu, B., Young, P. S., Su, B., Meek, R. M.D., Dalby, M. J. and Tsimbouri, P. M. (2016) Analysis of osteoclastogenesis / osteoblastogenesis on nanotopographical titania surfaces. [Data Collection]
Tsimbouri, P. , Fisher, L., Holloway, N., Sjöström, T., Nobbs, A.H., Meek, R. M.D., Su, B. and Dalby, M. (2016) Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates. [Data Collection] (Unpublished)