Multimorbidity PhD programme for Health Professionals

Publications

2025

Penfold RS, Bowman E, Vardy E, Sampson EL, Anand A, Guthrie B, MacLullich AMJ. Using Scores from the 4AT Delirium Detection Tool as an Indicator of Possible Dementia: A Study of 75,221 Older Adult Hospital Admissions. Age Ageing. 2025 May 14. doi: 10.1093/ageing/afaf144

Penfold RS, Farrow L, Hall AJ, Clement ND, Ward K, Donaldson L, Johansen A, Duckworth AD, Anand A, Hall DE, Guthrie B, MacLullich AMJ. Delirium on presentation with a hip fracture is associated with adverse outcomes: a multicentre observational study of 18,040 patients using national clinical registry data. Bone Joint J. 2025 Apr 1;107-B(4):470-478. doi: 10.1302/0301-620X.107B4.BJJ-2024-1164.R1.

Merriman, N., Walsh, ME, Ferris, H...Penfold RS, et al. Diagnostic test accuracy of screening tools for the detection of neurocognitive disorders in older adults post-trauma in acute care settings: a systematic review. Eur Geriatr Med 2025 Aug. doi: 10.1007/s41999-025-01287-9

Walker Heather, Khan Shabana, Padmanabhan Sandosh, Pell P. Jill, Lewsey Jim, Mackay Daniel, Dundas Ruth, Friday M. Jocelyn, Tran Q. B. Tran, Brown Denis, Ho Frederick, Hastie H, Claire, Fleming  Michael, Geue Claudia, Stevenson Alan, Du Toit Clea, Jani Bhautesh, Gallacher Katiet, Mark B. Patrick, Sullivan K. Michael. Analysis of the kidney failure risk equation implementation in routine clinical practice and health inequalities in chronic kidney disease care: a retrospective cohort study. BMC Nephrology. 2025;26(1):113. doi: 10.1186/s12882-025-04043-0

Walker Heather, Sullivan K. Michael, Jani Bhautesh, Gallacher Katie. Chronic kidney disease management in primary care: challenges and possible developments. British Journal of General Practice. 2025;75(752):104. doi: 10.3399/bjgp25X740829

Jones Catrin, Cairns Ross, Walker Heather, Welsh Silje, Edgar Benjamin, Stevenson Karen, Jani Bhautesh, Mark B. Patrick, Gallacher I. Katie. Exploration of treatment burden through examination of workload and patient capacity during transition onto kidney replacement therapy: a systematic review of qualitative research. BMC Medicine. 2025;23(1):61. doi: 10.1186/s12916-025-03904-7

Walker Heather, Carrero Juan-Jesus, Sullivan K. Michael, Field Ryan, Lees S. Jennifer, Hanlon Peter, Faucon Anne-Laure, Fu L. Edouard, Beridze Giorgi, Jani Bhautesh, Gallacher Katie, Mark B. Patrick. Frailty in Adults with CKD and Validation of the Kidney Failure Risk Equation in Frailty Subgroups. Clinical Journal of the American Society of Nephrology. 2025;20(8). doi: 10.2215/CJN.0000000739

Hill K, Owori R, Naisanga M, Owarwo N, Mills S, Stagg HR, Mpagama S, Sekaggya-Wiltshire C, Sloan DJ. Multimorbidity in tuberculosis (TB) and its impact on patient care (MITICare): a cross-sectional study nested within a prospective cohort study protocol. Wellcome Open Res 2025, 10:282 (https://doi.org/10.12688/wellcomeopenres.24237.1.

Burman W, Ellis J, Hale G, Hill K. Adequacy of recommendations for adverse event management in national and international treatment guidelines for rifampicin-susceptible tuberculosis: a systematic review. eClinicalMedicine 2025, Volume 82, 103148. DOI: 10.1016/j.eclinm.2025.103148

Murray, JL.K., Hernandez-Santiago, V., Sullivan, F. et al. Interprofessional collaborative practice in health and social care for people living with multimorbidity: a scoping review protocol. Syst Rev 14, 3 (2025). https://doi.org/10.1186/s13643-024-02730-x

Lambourg EJ, Fu EL, McGurnaghan S, Conway BR, Dhaun N, Grant CH, Pearson ER, Mark PB, Petrie J, Colhoun H, Bell S. Stopping versus continuing metformin in patients with advanced CKD: a nationwide Scottish target trial emulation study. American Journal of Kidney Diseases. 2025 Feb 1;85(2):196-204.

Grant CH, Sawhney S, Bell S. Reframing Acute Kidney Disease: Two Coins or Two Sides?. American Journal of Kidney Diseases. 2025 Jul 26.

Grant CH, Dahiya A, Palechuk T, Lambourg E, Tan B, Mehta RL, Pannu N, Bell S. Health inequalities and outcomes following acute kidney injury: a systematic review & meta-analyses of observational studies. BMC nephrology. 2025 Dec;26(1):1-28.

Grant CH, Bell S. Obesity and chronic kidney disease: the dual epidemic in cardiovascular health (in press). European Cardiology review.

Grant H. Christopher, Walker Heather , Barnett N. Karen, Mark B. Patrick, Colvin A. Lesley, Bell Samira. Multimorbidity and analgesic-related harms: a systematic review. British Journal of Anaesthesia. doi: 10.1016/j.bja.2025.02.012

Bezzina C, McQuade R, Lowe W, Mair F, Pope L. Shattering the shield: embracing complexity in undergraduate medical education. Clin Teach. 2025 Feb;22(1):e70018. doi:10.1111/tct.70018. PMID: 39832492; PMCID: PMC11745563

Corcoran N, Wilson N, Mackinnon S, et alQuantifying cost and health-related quality of life outcomes in different multimorbidity trajectories: a systematic review protocolBMJ Open 2025;15:e102096. doi: 10.1136/bmjopen-2025-102096

Carr AL, Broadbent P, Ho FK, et al. Associations of built environment features with multimorbidity: A systematic review protocol. Journal of Multimorbidity and Comorbidity. 2025;15. doi:10.1177/26335565251333278

Wilson N, Gajwani R, Fleming M, et alPhysical health trajectories of young people with neurodevelopmental conditions: a protocol for a systematic review of longitudinal studiesBMJ Open 2025;15:e090823. doi: 10.1136/bmjopen-2024-090823

Bowers SP, Black P, McCheyne L, Wilson D, Mills SEE, Agrawal U, Williams L, Quirk F, Bowden J. Current definitions of advanced multimorbidity: a protocol for a scoping review. BMJ Open. 2023 Nov 30;13(11):e076903. doi: 10.1136/bmjopen-2023-076903. PMID: 38035744; PMCID: PMC10689385.

Bowers, S. P., Ward, M., Weir, M. C., Mills, S. E., Williams, L., Bowden, J., & Quirk, F. (2025). Use of unscheduled care in the last year of life for people with multiple long-term health conditions: a retrospective cohort study of 299,361 decedentsBJGP open, BJGPO.2025.0049. Advance online publication. https://doi.org/10.3399/BJGPO.2025.0049

Bowers SP, Black P, McCheyne L, Wilson D, Penfold RS, Stapleton L, Channer P, Mills SEE, Williams L, Quirk F, Bowden J. Descriptions of advanced multimorbidity: A scoping review with content analysis. J Multimorb Comorb. 2025 Mar 18;15:26335565251326309. doi: 10.1177/26335565251326309.

 

2024

Penfold RS, Squires C, Angus A, Shenkin SD, Ibitoye T, Tieges Z, Neufeld KJ, Avelino-Silva TJ, Davis D, Anand A, Duckworth AD, Guthrie B, MacLullich AMJ. Delirium detection tools show varying completion rates and positive score rates when used at scale in routine practice in general hospital settings: A systematic review. J Am Geriatr Soc. 2024 May;72(5):1508-1524. doi: 10.1111/jgs.18751.

Merriman NA, Penfold RS, Brent L et al. Delirium and Cognitive Screening in National Hip Fracture Registries: Scoping Review Protocol. HRB Open Res 2024, 7:68

Falis M, Gema AP, Dong H, Daines L, Basetti S, Holder M, Penfold RS, Birch A, Alex B. Can GPT-3.5 generate and code discharge summaries? J Am Med Inform Assoc. 2024 Oct 1;31(10):2284-2293. doi: 10.1093/jamia/ocae132.

Penfold RS, Hunt A. Redefining risk in peri-operative frailty: towards routine frailty assessment and a whole pathway approach. Anaesthesia. 2024 Aug;79(8):797-800. doi: 10.1111/anae.16264.

Walker Heather, Day Scott, Grant H. Christopher, Jones Catrin, Ker Robert, Sullivan K. Michael, Jani Bhautesh, Gallacher K, Mark B. Patrick. Representation of multimorbidity and frailty in the development and validation of kidney failure prognostic prediction models: a systematic review. BMC Medicine. 2024;22(1):452. doi: 10.1186/s12916-024-03649-9

Walker Heather, Sullivan K. Michael, Jani Bhautesh, Mark B. Patrick, Gallacher I. Katie. Exploration of patients’ and healthcare professionals’ perspectives on kidney failure risk and the use of the kidney failure risk equation in MULTIPle lOng-term condItions aNd frailTy (MULTIPOINT) study: a qualitative interview and focus group study protocol. BMJ Open. 2024;14(10):e085843. doi: 10.1136/bmjopen-2024-085843

Scopazzini, M.S., Hill, K.J., Majonga, E.D., Zenner, D., Ayles, H. and Shah, A.S.V. (2024) ‘Imaging and Circulating Biomarker-Defined Cardiac Pathology in Pulmonary Tuberculosis: A Systematic Review’, Global Heart, 19(1), p. 84. Available at: https://doi.org/10.5334/gh.1369.

Senaratne, D. N. S., Koponen, M., Barnett, K. N., Smith, B. H., Hales, T. G., Marryat, L., & Colvin, L. A. (2025). Impact of adverse childhood experiences on analgesia-related outcomes: a systematic reviewBritish journal of anaesthesia134(2), 461–491. https://doi.org/10.1016/j.bja.2024.09.015

Senaratne, D. N. S., Thakkar, B., Smith, B. H., Hales, T. G., Marryat, L., & Colvin, L. A. (2024). The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysisBMC medicine22(1), 315. https://doi.org/10.1186/s12916-024-03505-w

Campbell F, McGregor S, Marryat L et al. The influence of maternal long term health conditions including multimorbidity on child oral health: A scoping review and evidence gap map protocol [version 2; peer review: 3 approved, 1 not approved]. Wellcome Open Res 2024, 9:299 (https://doi.org/10.12688/wellcomeopenres.21725.2)

2023

Penfold RS, Hall AJ, Anand A, Clement ND, Duckworth AD, MacLullich AMJ. Delirium in hip fracture patients admitted from home during the COVID-19 pandemic is associated with higher mortality, longer total length of stay, need for post-acute inpatient rehabilitation, and readmission to acute services. Bone Jt Open. 2023 Jun 16;4(6):447-456.

Clement ND, Penfold RS, Duffy A, Murthy K, MacLullich AMJ, Duckworth AD. Completion of the Emergency Department "Big 6" in Patients with an Acute Hip Fracture Is Associated with a Lower Mortality Risk and Shorter Length of Hospital Stay. J Clin Med. 2023 Aug 26;12(17):5559. doi: 10.3390/jcm12175559. PMID: 37685625; PMCID: PMC10488202.

Senaratne D, Colvin L. Chronic pain associated with temporomandibular disorders BMJ 2023; 383 :p2877 doi:10.1136/bmj.p2877

Nicolson, K. P., Mills, S. E. E., Senaratne, D. N. S., Colvin, L. A., & Smith, B. H. (2023). What is the association between childhood adversity and subsequent chronic pain in adulthood? A systematic reviewBJA open6, 100139. https://doi.org/10.1016/j.bjao.2023.100139