2024

MacDonald, L. et al. (2024) Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis. Immunity, 57(12), 2843-2862.e12. (doi: 10.1016/j.immuni.2024.11.004) (PMID:39609125)

Alivernini, Stefano, Cañete, Juan D., Bacardit, Jaume and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2024) Using explainable artificial intelligence to predict and forestall flare in rheumatoid arthritis. Nature Medicine, 30(4), pp. 925-926. (doi: 10.1038/s41591-024-02818-w) (PMID:38361121)

Coletto, Lavinia Agra, Marino, Valentina, Rizzo, Chiara, Bruno, Dario, Caporali, Roberto, Gremese, Elisa, D'Agostino, Maria Antonietta and Alivernini, Stefano (2024) Intensive training programme for ultrasound-guided minimally invasive synovial tissue biopsy on knees and wrists in different phases of inflammation. RMD Open, 10(1), e003705. (doi: 10.1136/rmdopen-2023-003705) (PMID:38351051) (PMCID:PMC10868172)

2022

Najm, A. et al. (2022) EULAR Points to consider for minimal reporting requirements in synovial tissue research in rheumatology. Annals of the Rheumatic Diseases, 81(12), pp. 1640-1646. (doi: 10.1136/annrheumdis-2021-221875) (PMID:35210263)

Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 and Alivernini, Stefano (2022) Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission. Nature Reviews Rheumatology, 18, pp. 384-397. (doi: 10.1038/s41584-022-00790-8) (PMID:35672464)

Farina, L. et al. (2022) Pro nerve growth factor and its receptor p75NTR activate inflammatory responses in synovial fibroblasts: a novel targetable mechanism in arthritis. Frontiers in Immunology, 13, 818630. (doi: 10.3389/fimmu.2022.818630) (PMID:35309353) (PMCID:PMC8931659)

2021

Clayton, S. A. et al. (2021) Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48. Science Advances, 7(50), eabl5182. (doi: 10.1126/sciadv.abl5182) (PMID:34878835)

MacDonald, L. et al. (2021) COVID-19 and RA share SPP1 myeloid pathway that drives PD-L1pos neutrophils and CD14pos monocytes. JCI Insight, 6(13), e147413. (doi: 10.1172/jci.insight.147413) (PMID:34143756) (PMCID:PMC8328085)

Wang, Y. et al. (2021) Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis. Nature Communications, 12, 2343. (doi: 10.1038/s41467-021-22365-z) (PMID:33879788) (PMCID:PMC8058094)

2020

Alivernini, S. et al. (2020) Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nature Medicine, 26(8), pp. 1295-1306. (doi: 10.1038/s41591-020-0939-8) (PMID:32601335)

2019

Finlay, S. et al. (2019) Presence of the MerTK Receptor on Human Synovial Tissue Macrophages Lowers Inflammatory Cytokine Production and Activation of the MerTK+CD206+ Subpopulation Limits the Inflammatory Response of Synovial Fibroblasts. 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA, 08-13 Nov 2019.

Elmesmari, A. et al. (2019) Do Functional Interactions Between Macrophages and Synovial Fibroblasts Drive Synovial Pathology or Resolution of Inflammation? European League Against Rheumatism (EULAR) 2019 Congress, Madrid, Spain, 12-15 Jun 2019.

Finlay, S. et al. (2019) Single-cell Transcriptomic and Functional Analyses Reveal Novel Heterogeneity in Pathogenic Pathways Mediated by Human Synovial Tissue Macrophages. European League Against Rheumatism (EULAR) 2019 Congress, Madrid, Spain, 12-15 Jun 2019.

2018

Alivernini, S. et al. (2018) Histological Features and Tissue-Macrophage Phenotype of Synovial Biopsies Identify RA Patients in Sustained Remission at Risk of Disease Flare after Treatment Tapering or Discontinuation. 2018 ACR/ARHP Annual Meeting, Chicago, IL, 19-24 Oct 2018. (Unpublished)

Alivernini, S., Tolusso, B., Ferraccioli, G., Gremese, E., Kurowska-Stolarska, M. ORCID: https://orcid.org/0000-0003-2124-7777 and McInnes, I.B. ORCID: https://orcid.org/0000-0002-6462-4280 (2018) Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells. Clinical and Experimental Immunology, 193(1), pp. 13-23. (doi: 10.1111/cei.13098) (PMID:29315512) (PMCID:PMC6038003)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Bui, Laura, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Federico, Francesco, Gremese, Elisa, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2018) Stolarska Synovial Tissue CD1c+ Dendritic Cells in Rheumatoid Arthritis Express High Levels of the Epigenetic Regulator of Inflammation, Microrna-155 and Inflammatory Cytokines. EULAR 2018: Annual European Congress of Rheumatology, Amsterdam, Netherlands, 13-16 June 2018. (Unpublished)

Finlay, Samuel, Alivernini, Stefano, Elmesmari, Aziza, Tolusso, Barbara, Ferraccioli, Gianfranco, Gremese, Elisa, Petricca, Luca, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280, Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 and Filer, Andrew (2018) Activation of Mertk+cd206+ Subpopulation of Human Synovial Tissue-Resident Macrophages Limits Inflammatory Response. EULAR 2018: Annual European Congress of Rheumatology, Amsterdam, Netherlands, 13-16 June 2018. (Unpublished)

Alivernini, Stefano, Gremese, Elisa, McSharry, Charles, Tolusso, Barbara, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2018) MicroRNA-155—at the critical interface of innate and adaptive immunity in arthritis. Frontiers in Immunology, 8, 1932. (doi: 10.3389/fimmu.2017.01932) (PMID:29354135) (PMCID:PMC5760508)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Petricca, Luca, Gremese, Elisa, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2018) Synovial Tissue of RA Patients in Remission Contains a Unique Population of Regulatory Macrophages. Microphage Biology in the Single-Cell Era, Ghent, Belgium, 2018. (Unpublished)

2017

Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 and Alivernini, Stefano (2017) Synovial tissue macrophages: friend or foe? RMD Open, 3(2), e000527. (doi: 10.1136/rmdopen-2017-000527) (PMID:29299338) (PMCID:PMC5729306)

Kurowska-Stolarska, M. et al. (2017) MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications, 8, 15877. (doi: 10.1038/ncomms15877) (PMID:28639625) (PMCID:PMC5489689)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Petricca, Luca, Gremese, Elisa, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2017) Synovial Tissue of RA Patients in Remission Contains a Unique Population of Regulatory Macrophages. EULAR 2017: Annual European Congress of Rheumatology, Madrid, Spain, 14-17 June 2017. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2017) Characterisation of Synovium Tissues Macropahges. Rheumatology 2017, Birmingham, UK, 25-27 April 2017. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Petricca, Luca, Gremese, Elisa, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2017) Synovial Tissue of RA Patients in Remission Contains a Unique Population of Regulatory Macrophages. 37th European Workshop for Rheumatology Research (EWRR 2017), Athens, Greece, 2-4 March 2017. (Unpublished)

2016

Alivernini, S. et al. (2016) MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis. Nature Communications, 7, 12970. (doi: 10.1038/ncomms12970) (PMID:27671860) (PMCID:PMC5052655)

Elmesmari, Aziza, Alivernini, Stefano, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2016) Targeting miR-155 in Rheumatoid Arthritis B Cells Reduces Antibody Production. Scottish Society of Rheumatology Meeting 2016, Dundee, 2016. (Unpublished)

2013

Tange, Clare E., Alivernini, Stefano, Gilchrist, Derek S., Crawford, Lynn, Rainey, Ashleigh-Ann, Baxter, Derek, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2013) Mir-34a in Rheumatoid Arthritis: characterisation of elevated synovial expression and association with treatment resistance. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S403.

2011

Kurowska-Stolarska, M. et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11193-11198. (doi: 10.1073/pnas.1019536108) (PMID:21690378)

Alivernini, S. et al. (2011) The role of microRNA-34 and microRNA-22 in dendritic cells and monocyte activation in rheumatoid arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Chicago, IL USA, 4-9 Nov 2011, S654.

Articles

MacDonald, L. et al. (2024) Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis. Immunity, 57(12), 2843-2862.e12. (doi: 10.1016/j.immuni.2024.11.004) (PMID:39609125)

Alivernini, Stefano, Cañete, Juan D., Bacardit, Jaume and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2024) Using explainable artificial intelligence to predict and forestall flare in rheumatoid arthritis. Nature Medicine, 30(4), pp. 925-926. (doi: 10.1038/s41591-024-02818-w) (PMID:38361121)

Coletto, Lavinia Agra, Marino, Valentina, Rizzo, Chiara, Bruno, Dario, Caporali, Roberto, Gremese, Elisa, D'Agostino, Maria Antonietta and Alivernini, Stefano (2024) Intensive training programme for ultrasound-guided minimally invasive synovial tissue biopsy on knees and wrists in different phases of inflammation. RMD Open, 10(1), e003705. (doi: 10.1136/rmdopen-2023-003705) (PMID:38351051) (PMCID:PMC10868172)

Najm, A. et al. (2022) EULAR Points to consider for minimal reporting requirements in synovial tissue research in rheumatology. Annals of the Rheumatic Diseases, 81(12), pp. 1640-1646. (doi: 10.1136/annrheumdis-2021-221875) (PMID:35210263)

Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 and Alivernini, Stefano (2022) Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission. Nature Reviews Rheumatology, 18, pp. 384-397. (doi: 10.1038/s41584-022-00790-8) (PMID:35672464)

Farina, L. et al. (2022) Pro nerve growth factor and its receptor p75NTR activate inflammatory responses in synovial fibroblasts: a novel targetable mechanism in arthritis. Frontiers in Immunology, 13, 818630. (doi: 10.3389/fimmu.2022.818630) (PMID:35309353) (PMCID:PMC8931659)

Clayton, S. A. et al. (2021) Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48. Science Advances, 7(50), eabl5182. (doi: 10.1126/sciadv.abl5182) (PMID:34878835)

MacDonald, L. et al. (2021) COVID-19 and RA share SPP1 myeloid pathway that drives PD-L1pos neutrophils and CD14pos monocytes. JCI Insight, 6(13), e147413. (doi: 10.1172/jci.insight.147413) (PMID:34143756) (PMCID:PMC8328085)

Wang, Y. et al. (2021) Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis. Nature Communications, 12, 2343. (doi: 10.1038/s41467-021-22365-z) (PMID:33879788) (PMCID:PMC8058094)

Alivernini, S. et al. (2020) Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nature Medicine, 26(8), pp. 1295-1306. (doi: 10.1038/s41591-020-0939-8) (PMID:32601335)

Alivernini, S., Tolusso, B., Ferraccioli, G., Gremese, E., Kurowska-Stolarska, M. ORCID: https://orcid.org/0000-0003-2124-7777 and McInnes, I.B. ORCID: https://orcid.org/0000-0002-6462-4280 (2018) Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells. Clinical and Experimental Immunology, 193(1), pp. 13-23. (doi: 10.1111/cei.13098) (PMID:29315512) (PMCID:PMC6038003)

Alivernini, Stefano, Gremese, Elisa, McSharry, Charles, Tolusso, Barbara, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2018) MicroRNA-155—at the critical interface of innate and adaptive immunity in arthritis. Frontiers in Immunology, 8, 1932. (doi: 10.3389/fimmu.2017.01932) (PMID:29354135) (PMCID:PMC5760508)

Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 and Alivernini, Stefano (2017) Synovial tissue macrophages: friend or foe? RMD Open, 3(2), e000527. (doi: 10.1136/rmdopen-2017-000527) (PMID:29299338) (PMCID:PMC5729306)

Kurowska-Stolarska, M. et al. (2017) MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications, 8, 15877. (doi: 10.1038/ncomms15877) (PMID:28639625) (PMCID:PMC5489689)

Alivernini, S. et al. (2016) MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis. Nature Communications, 7, 12970. (doi: 10.1038/ncomms12970) (PMID:27671860) (PMCID:PMC5052655)

Kurowska-Stolarska, M. et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11193-11198. (doi: 10.1073/pnas.1019536108) (PMID:21690378)

Conference or Workshop Item

Finlay, S. et al. (2019) Presence of the MerTK Receptor on Human Synovial Tissue Macrophages Lowers Inflammatory Cytokine Production and Activation of the MerTK+CD206+ Subpopulation Limits the Inflammatory Response of Synovial Fibroblasts. 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA, 08-13 Nov 2019.

Elmesmari, A. et al. (2019) Do Functional Interactions Between Macrophages and Synovial Fibroblasts Drive Synovial Pathology or Resolution of Inflammation? European League Against Rheumatism (EULAR) 2019 Congress, Madrid, Spain, 12-15 Jun 2019.

Finlay, S. et al. (2019) Single-cell Transcriptomic and Functional Analyses Reveal Novel Heterogeneity in Pathogenic Pathways Mediated by Human Synovial Tissue Macrophages. European League Against Rheumatism (EULAR) 2019 Congress, Madrid, Spain, 12-15 Jun 2019.

Alivernini, S. et al. (2018) Histological Features and Tissue-Macrophage Phenotype of Synovial Biopsies Identify RA Patients in Sustained Remission at Risk of Disease Flare after Treatment Tapering or Discontinuation. 2018 ACR/ARHP Annual Meeting, Chicago, IL, 19-24 Oct 2018. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Bui, Laura, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Federico, Francesco, Gremese, Elisa, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2018) Stolarska Synovial Tissue CD1c+ Dendritic Cells in Rheumatoid Arthritis Express High Levels of the Epigenetic Regulator of Inflammation, Microrna-155 and Inflammatory Cytokines. EULAR 2018: Annual European Congress of Rheumatology, Amsterdam, Netherlands, 13-16 June 2018. (Unpublished)

Finlay, Samuel, Alivernini, Stefano, Elmesmari, Aziza, Tolusso, Barbara, Ferraccioli, Gianfranco, Gremese, Elisa, Petricca, Luca, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280, Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 and Filer, Andrew (2018) Activation of Mertk+cd206+ Subpopulation of Human Synovial Tissue-Resident Macrophages Limits Inflammatory Response. EULAR 2018: Annual European Congress of Rheumatology, Amsterdam, Netherlands, 13-16 June 2018. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Petricca, Luca, Gremese, Elisa, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2018) Synovial Tissue of RA Patients in Remission Contains a Unique Population of Regulatory Macrophages. Microphage Biology in the Single-Cell Era, Ghent, Belgium, 2018. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Petricca, Luca, Gremese, Elisa, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2017) Synovial Tissue of RA Patients in Remission Contains a Unique Population of Regulatory Macrophages. EULAR 2017: Annual European Congress of Rheumatology, Madrid, Spain, 14-17 June 2017. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2017) Characterisation of Synovium Tissues Macropahges. Rheumatology 2017, Birmingham, UK, 25-27 April 2017. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, Tolusso, Barbara, Vaughan, Diane ORCID: https://orcid.org/0000-0002-4530-2278, Petricca, Luca, Gremese, Elisa, Ferraccioli, Gianfranco, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2017) Synovial Tissue of RA Patients in Remission Contains a Unique Population of Regulatory Macrophages. 37th European Workshop for Rheumatology Research (EWRR 2017), Athens, Greece, 2-4 March 2017. (Unpublished)

Elmesmari, Aziza, Alivernini, Stefano, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2016) Targeting miR-155 in Rheumatoid Arthritis B Cells Reduces Antibody Production. Scottish Society of Rheumatology Meeting 2016, Dundee, 2016. (Unpublished)

Conference Proceedings

Tange, Clare E., Alivernini, Stefano, Gilchrist, Derek S., Crawford, Lynn, Rainey, Ashleigh-Ann, Baxter, Derek, McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Kurowska-Stolarska, Mariola ORCID: https://orcid.org/0000-0003-2124-7777 (2013) Mir-34a in Rheumatoid Arthritis: characterisation of elevated synovial expression and association with treatment resistance. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S403.

Alivernini, S. et al. (2011) The role of microRNA-34 and microRNA-22 in dendritic cells and monocyte activation in rheumatoid arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Chicago, IL USA, 4-9 Nov 2011, S654.