Prof Foo Liew

  • Emeritus Professor (Institute of Infection Immunity & Inflammation)

email: Foo.Liew@glasgow.ac.uk

RI III, Sir Graeme Davies Building, 120 University Place, Glasgow, G12 8TA

Publications

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Number of items: 178.

2021

Donate, P. B. et al. (2021) Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America, 118(1), e201712011. (doi: 10.1073/pnas.2017120118) (PMID:33443169) (PMCID:PMC7817209)

2020

Akbar, M., Garcia-Melchor, E., Chilaka, S., Little, K. J., Sood, S., Reilly, J. H., Liew, F. Y., McInnes, I. B. and Millar, N. L. (2020) Attenuation of Dupuytren’s fibrosis via targeting of the STAT-1 modulated IL-13RA1 response. Science Advances, 6(28), eaaz8272. (doi: 10.1126/sciadv.aaz8272)

2019

Colón, D. F. et al. (2019) Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis. Critical Care, 23, 113. (doi: 10.1186/s13054-019-2407-8) (PMID:30961634) (PMCID:PMC6454713)

2018

Castanheira, F. V. e. S. et al. (2018) CCR5-positive inflammatory monocytes are crucial for control of sepsis. Shock, 52(5), e100-e106. (doi: 10.1097/SHK.0000000000001301) (PMID:30724784)

Marques, R. E., Besnard, A.-G., Maillet, I., Fagundes, C. T., Souza, D. G., Ryffel, B., Teixeira, M. M., Liew, F. Y. and Guabiraba, R. (2018) Interleukin-33 contributes to disease severity in Dengue virus infection in mice. Immunology, 155(4), pp. 477-490. (doi: 10.1111/imm.12988) (PMID:30098206)

Strangward, P. et al. (2018) Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria. Proceedings of the National Academy of Sciences of the United States of America, 115(28), pp. 7404-7409. (doi: 10.1073/pnas.1801737115) (PMID:29954866) (PMCID:PMC6048513)

Talbot, J. et al. (2018) Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells. Arthritis Research and Therapy, 20, 119. (doi: 10.1186/s13075-018-1609-9) (PMID:29884199) (PMCID:PMC5994132)

Castanheira, F. V. E. S. et al. (2018) The atypical chemokine receptor ACKR2 is protective against sepsis. Shock, 49(6), pp. 682-689. (doi: 10.1097/SHK.0000000000000969) (PMID:29589840)

Staurengo-Ferrari, L. et al. (2018) Interleukin-33 receptor (ST2) deficiency improves the outcome of Staphylococcus aureus-induced septic arthritis. Frontiers in Immunology, 9, (doi: 10.3389/fimmu.2018.00962) (PMID:29867945) (PMCID:PMC5968393)

Peres, R. S. et al. (2018) TGF-β signalling defect is linked to low CD39 expression on regulatory T cells and methotrexate resistance in rheumatoid arthritis. Journal of Autoimmunity, (doi: 10.1016/j.jaut.2018.01.004) (PMID:29426578)

2017

Cole, S. L. et al. (2017) M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. JCI Insight, 2(7), e91868. (doi: 10.1172/jci.insight.91868) (PMID:28405622) (PMCID:PMC5374077)

Nascimento, D. C. et al. (2017) IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nature Communications, 8, 14919. (doi: 10.1038/ncomms14919) (PMID:28374774) (PMCID:PMC5382289)

2016

Liew, F. Y., Girard, J.-P. and Turnquist, H. R. (2016) Interleukin-33 in health and disease. Nature Reviews Immunology, 16(11), pp. 676-689. (doi: 10.1038/nri.2016.95) (PMID:27640624)

Zarpelon, A. C. et al. (2016) Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB Journal, 30(1), pp. 54-65. (doi: 10.1096/fj.14-267146) (PMID:26310268)

Fu, A. K. Y. et al. (2016) IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline. Proceedings of the National Academy of Sciences of the United States of America, 113(19), E2705-E2713. (doi: 10.1073/pnas.1604032113) (PMID:27091974) (PMCID:PMC4868478)

2015

Malcolm, J. et al. (2015) IL-33 exacerbates periodontal disease through induction of RANKL. Journal of Dental Research, 94(7), pp. 968-975. (doi: 10.1177/0022034515577815) (PMID:25808546)

Millar, N. L. , Gilchrist, D., Akbar, M., Reilly, J. H., Kerr, S. C., Campbell, A. L., Murrell, G. A.C., Liew, F. Y., Kurowska-Stolarska, M. and McInnes, I. B. (2015) MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease. Nature Communications, 6, 6774. (doi: 10.1038/ncomms7774) (PMID:25857925) (PMCID:PMC4403384)

Liew, F. Y. (2015) Cigarette smoke resets the alarmin IL-33 in COPD. Immunity, 42(3), pp. 401-403. (doi: 10.1016/j.immuni.2015.02.014) (PMID:25786171)

Besnard, A.-G., Guabiraba Brito, R., Niedbala, W., Palomo, J., Reverchon, F., Shaw, T. N., Couper, K. N., Ryffel, B. and Liew, F. (2015) IL-33-mediated protection against experimental cerebral malaria is linked to induction of Type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. PLoS Pathogens, 11(2), e1004607. (doi: 10.1371/journal.ppat.1004607) (PMID:25659095) (PMCID:PMC4450060)

Peres, R. S. et al. (2015) Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America, 112(8), pp. 2509-2514. (doi: 10.1073/pnas.1424792112) (PMID:25675517)

2014

Li, D. et al. (2014) IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice. Journal of Allergy and Clinical Immunology, 134(6), 1422-1432.e11. (doi: 10.1016/j.jaci.2014.05.011) (PMID:24985397) (PMCID:PMC4258609)

Barbour, M. et al. (2014) IL-33 attenuates the development of experimental autoimmune uveitis. European Journal of Immunology, 44(11), pp. 3320-3329. (doi: 10.1002/eji.201444671) (PMID:25116404) (PMCID:PMC4449115)

Sattler, S. et al. (2014) IL-10-producing regulatory B cells induced by IL-33 (BregIL-33) effectively attenuate mucosal inflammatory responses in the gut. Journal of Autoimmunity, 50, pp. 107-122. (doi: 10.1016/j.jaut.2014.01.032) (PMID:24491821) (PMCID:PMC4012142)

Mirchandani, A. S., Besnard, A.-G., Yip, E., Scott, C., Bain, C. C., Cerovic, V., Salmond, R. J. and Liew, F. J. (2014) Type 2 innate lymphoid cells drive CD4+ Th2 cell responses. Journal of Immunology, 192(5), pp. 2442-2448. (doi: 10.4049/jimmunol.1300974)

Guabiraba Brito, R. et al. (2014) IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunology, 7(5), pp. 1079-1093. (doi: 10.1038/mi.2013.124)

Niedbala, W. et al. (2014) Nitric oxide enhances Th9 cell differentiation and airway inflammation. Nature Communications, 5(4575), (doi: 10.1038/ncomms5575)

2013

Gabriele, L. et al. (2013) Novel allergic asthma model demonstrates ST2-dependent dendritic cell targeting by cypress pollen. Journal of Allergy and Clinical Immunology, 132(3), 686-695.e7. (doi: 10.1016/j.jaci.2013.02.037)

Magro, D.A.C., Hohmann, M.S.N., Mizokami, S.S., Cunha, T.M., Alves-Filho, J.C., Casagrande, R., Ferreira, S.H., Liew, F.Y., Cunha, F.Q. and Verri Jr, W.A. (2013) An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice. Brazilian Journal of Medical and Biological Research, 46(7), pp. 601-606. (doi: 10.1590/1414-431x20132894) (PMID:23903682) (PMCID:PMC3859337)

Niedbala, W., Besnard, A.-G., Jiang, H.-R., Alves-Filho, J.C., Fukada, S.Y., Nascimento, D., Mitani, A., Pushparaj, P., Alqahtani, M.H. and Liew, F.Y. (2013) Nitric oxide-induced regulatory T cells inhibit Th17 but not Th1 cell differentiation and function. Journal of Immunology, 191(1), pp. 164-170. (doi: 10.4049/jimmunol.1202580)

Zarpelon, A.C., Cunha, T.M., Alves-Filho, J.C., Pinto, L.G., Ferreira, S.H., McInnes, I.B. , Xu, D., Liew, F.Y., Cunha, F.Q. and Verri, W.A. (2013) IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2. British Journal of Pharmacology, 169(1), pp. 90-101. (doi: 10.1111/bph.12110) (PMID:23347081) (PMCID:PMC3632241)

2012

Salmond, R.J., Mirchandani, A.S., Besnard, A.-G., Bain, C.C., Thomson, N.C. and Liew, F.Y. (2012) IL-33 induces innate lymphoid cell–mediated airway inflammation by activating mammalian target of rapamycin. Journal of Allergy and Clinical Immunology, 130(5), pp. 1159-1166. (doi: 10.1016/j.jaci.2012.05.018)

Komai-Koma, M. et al. (2012) Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice. Allergy, 67(9), pp. 1118-1126. (doi: 10.1111/j.1398-9995.2012.02859.x) (PMID:22702477) (PMCID:PMC3660789)

Jiang, H.-R. et al. (2012) IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages. European Journal of Immunology, 42(7), pp. 1804-1814. (doi: 10.1002/eji.201141947)

Liew, F.Y. (2012) IL-33: a Janus cytokine. Annals of the Rheumatic Diseases, 71(Sup. 2), i101-i104. (doi: 10.1136/annrheumdis-2011-200589)

Mirchandani, A. S., Salmond, R. J. and Liew, F. Y. (2012) Interleukin-33 and the function of innate lymphoid cells. Trends in Immunology, 33(8), pp. 389-396. (doi: 10.1016/j.it.2012.04.005)

2011

Turnquist, H. R. et al. (2011) IL-33 expands suppressive CD11b+ Gr-1int and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. Journal of Immunology, 187(9), pp. 4598-4610. (doi: 10.4049/jimmunol.1100519)

Hueber, A. J., Alves-Filho, J. C., Asquith, D. L., Michels, C., Millar, N. L. , Reilly, J. H., Graham, G. J. , Liew, F. Y., Miller, A. M. and McInnes, I. B. (2011) IL-33 induces skin inflammation with mast cell and neutrophil activation. European Journal of Immunology, 41(8), pp. 2229-2237. (doi: 10.1002/eji.201041360) (PMID:21674479)

Miller, A. M. and Liew, F. Y. (2011) The IL-33/ST2 pathway — A new therapeutic target in cardiovascular disease. Pharmacology and Therapeutics, 131(2), pp. 179-186. (doi: 10.1016/j.pharmthera.2011.02.005)

Kurowska-Stolarska, M. et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11193-11198. (doi: 10.1073/pnas.1019536108) (PMID:21690378)

Zaiss, M. M. et al. (2011) IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-α–mediated bone loss. Journal of Immunology, 186(11), pp. 6097-6105. (doi: 10.4049/jimmunol.1003487) (PMID:21515798)

Niedbala, W., Alves-Filho, J. C., Fukada, S. Y., Vieira, S. M., Mitani, A., Sonego, F., Mirchandani, A., Nascimento, D. C., Cunha, F. Q. and Liew, F. Y. (2011) Regulation of type 17 helper T-cell function by nitric oxide during inflammation. Proceedings of the National Academy of Sciences of the United States of America, 108(22), pp. 9220-9225. (doi: 10.1073/pnas.1100667108)

Culshaw, S. , McInnes, I. B. and Liew, F. Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38(S11), pp. 106-113. (doi: 10.1111/j.1600-051X.2010.01669.x) (PMID:21323707)

Kinane, D. F. et al. (2011) Host-response: understanding the cellular and molecular mechanisms of host-microbial interactions - consensus of the Seventh European Workshop on Periodontology. Journal of Clinical Periodontology, 38(S11), pp. 44-48. (doi: 10.1111/j.1600-051X.2010.01682.x)

Komai-Koma, M., Gilchrist, D. S., McKenzie, A. N. J., Goodyear, C. S. , Xu, D. and Liew, F. Y. (2011) IL-33 activates B1 cells and exacerbates contact sensitivity. Journal of Immunology, 186(4), pp. 2584-2591. (doi: 10.4049/jimmunol.1002103)

Pitman, N., Asquith, D.L., Murphy, G., Liew, F.Y. and McInnes, I.B. (2011) Collagen-induced arthritis is not impaired in mast cell-deficient mice. Annals of the Rheumatic Diseases, 70(6), pp. 1170-1171. (doi: 10.1136/ard.2010.134528) (PMID:21131642)

2010

Stolarski, B., Kurowska-Stolarska, M. , Kewin, P., Xu, D. and Liew, F. Y. (2010) IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation. Journal of Immunology, 185(6), pp. 3472-3480. (doi: 10.4049/jimmunol.1000730)

Miller, A. M., Asquith, D. L., Hueber, A. J., Anderson, L. A., Holmes, W. M. , McKenzie, A. N., Xu, D., Sattar, N. , McInnes, I. B. and Liew, F. Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107(5), pp. 650-658. (doi: 10.1161/CIRCRESAHA.110.218867) (PMID:20634488) (PMCID:PMC4254700)

Verri, W. A. et al. (2010) IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases, 69(9), pp. 1697-1703. (doi: 10.1136/ard.2009.122655) (PMID:20472598)

McLaren, J. E., Michael, D. R., Salter, R. C., Ashlin, T. G., Calder, C. J., Miller, A. M., Liew, F. Y. and Ramji, D. P. (2010) IL-33 Reduces Macrophage Foam Cell Formation. Journal of Immunology, 185(2), pp. 1222-1229. (doi: 10.4049/jimmunol.1000520)

Xu, D. et al. (2010) IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology, 184(5), pp. 2620-2626. (doi: 10.4049/jimmunol.0902685) (PMID:20139274)

Asquith, D. L., Miller, A. M., Hueber, A. J., Liew, F. Y., Sattar, N. and McInnes, I. B. (2010) Apolipoprotein E-deficient mice are resistant to the development of collagen-induced arthritis. Arthritis and Rheumatism, 62(2), pp. 472-477. (doi: 10.1002/art.27205) (PMID:20112375)

Liew, F. Y., Pitman, N. I. and McInnes, I. B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature Reviews Immunology, 10(2), pp. 103-110. (doi: 10.1038/nri2692) (PMID:20081870)

Alves Filho, J. C. et al. (2010) Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection. Nature Medicine, 16(6), pp. 708-712. (doi: 10.1038/nm.2156)

Murphy, G.E.J., Xu, D., Liew, F.Y. and McInnes, I.B. (2010) Role of interleukin 33 in human immunopathology. Annals of the Rheumatic Diseases, 69(Suppl), pp. 43-47. (doi: 10.1136/ard.2009.120113) (PMID:19995743)

Kurowska-Stolarska, M. , Ballantine, L., Stolarski, B., Hunter, J., Hueber, A., Gracie, J.A., Liew, F. Y. and McInnes, I. B. (2010) miR-155 and miR-34a regulate proinflammatory cytokine production by human monocytes. In: European Workshop for Rheumatology Research, Bamberg, Germany, 4-7 Mar 2010, A30-A30. (doi: 10.1136/ard.2010.129619g)

2009

Kurowska-Stolarska, M. et al. (2009) IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation. Journal of Immunology, 183(10), pp. 6469-6477. (doi: 10.4049/jimmunol.0901575) (PMID:19841166)

Asquith, D. L., Miller, A. M., McInnes, I. B. and Liew, F. Y. (2009) Animal models of rheumatoid arthritis. European Journal of Immunology, 39(8), pp. 2040-2044. (doi: 10.1002/eji.200939578) (PMID:19672892)

Pushparaj, P. N., Tay, H. K., H'Ng, S. C., Pitman, N., Xu, D., McKenzie, A., Liew, F. Y. and Melendez, A. J. (2009) The cytokine interleukin-33 mediates anaphylactic shock. Proceedings of the National Academy of Sciences of the United States of America, 106(24), pp. 9773-9778. (doi: 10.1073/pnas.0901206106)

McKimmie, C. S. et al. (2009) A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. Blood, 113(18), pp. 4224-4231. (doi: 10.1182/blood-2008-08-174698) (PMID:19202130)

Lemos, H. P. et al. (2009) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ  production. Proceedings of the National Academy of Sciences of the United States of America, 106(14), pp. 5954-5959. (doi: 10.1073/pnas.0812782106) (PMID:19289819)

Trieu, A., Bokil, N., Dunn, J. A., Roberts, T. L., Xu, D., Liew, F. Y., Hume, D. A., Stacey, K. J. and Sweet, M. J. (2009) TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium. Immunology and Cell Biology, 87(3), pp. 218-225. (doi: 10.1038/icb.2008.95)

Jiang, H., Al Rasebi, Z., Mensah-Brown, E., Shahin, A., Xu, D., Goodyear, C. , Fukada, S., Liu, F., Liew, F. and Lukic, M. (2009) Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis. Journal of Immunology, 182(2), pp. 1167-1173.

Asquith, D.L., Miller, A.L., McInnes, I.B. and Liew, F.Y. (2009) Autoimmune disease: rheumatoid arthritis. Animal models of rheumatoid arthritis. European Journal of Immunology, 39, pp. 1991-2058.

2008

Kurowska-Stolarska, M. et al. (2008) IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4. Journal of Immunology, 181(7), pp. 4780-4790.

Niedbala, W., Cai, B., Wei, X., Patakas, A., Leung, B. P., McInnes, I. and Liew, F. Y. (2008) Interleukin 27 attenuates collagen-induced arthritis. Annals of the Rheumatic Diseases, 67(10), pp. 1474-1479. (doi: 10.1136/ard.2007.083360) (PMID:18199596)

McKimmie, C. S. et al. (2008) Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of Immunology, 181(5), pp. 3353-3363. (doi: 10.4049/jimmunol.181.11.8170-a) (PMID:19039854)

Kurowska-Stolarska, M. S. , Kewin, P., Stolarski, B., Fraser, A., Xu, D., McInnes, I. and Liew, F. Y. (2008) A role of IL-33 in bone turnover. In: 72nd Annual Scientific Meeting of the American College of Rheumatology and the 43rd Annual Scientific Meeting of the Association of Rheumatology Health Professionals, San Francisco CA, USA, 24-29 Oct 2008, S895.

Xu, D. et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proceedings of the National Academy of Sciences of the United States of America, 105(31), pp. 10913-10918. (doi: 10.1073/pnas.0801898105) (PMID:18667700) (PMCID:PMC2491487)

Grespan, R., Fukada, S. Y., Lemos, H. P., Vieira, S. M., Napimoga, M. H., Teixeira, M. M., Fraser, A. R., Liew, F. Y., McInnes, I. B. and Cunha, F. Q. (2008) CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis. Arthritis and Rheumatism, 58(7), pp. 2030-2040. (doi: 10.1002/art.23597) (PMID:18576322)

Turnquist, H. R., Sumpter, T. L., Tsung, A., Zahorchak, A. F., Nakao, A., Nau, G. J., Liew, F. Y., Geller, D. A. and Thomson, A. W. (2008) IL-1 β-driven ST2L express ion promotes maturation resistance in rapamycin-conditioned dendritic cells. Journal of Immunology, 181(1), pp. 62-72.

Turnquist, H. R., Sumpter, T. L., Tsung, A., Zahorchak, A. F., Nakao, A., Nau, G. J., Liew, F. Y., Geller, D. A. and Thomson, A. W. (2008) IL-1β-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells. Journal of Immunology, 181(1), pp. 62-72. (doi: 10.4049/jimmunol.181.1.62)

Yang, C.-H., Tian, L., Ling, G.-S., Trendell‐Smith, N. J., Ma, L., Lo, C.-K., Stott, D. I., Liew, F. Y. and Huang, F.-P. (2008) Correction: Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: Roles of IL‐2versusIL‐15. European Journal of Immunology, 38(7), p. 2046. (doi: 10.1002/eji.200890028)

Yang, C.-H., Tian, L., Ling, G.-S., Trendell-Smith, N. J., Ma, L., Lo, C.-K., Stott, D. I., Liew, F. Y. and Huang, F.-P. (2008) Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: Roles of IL-2 versus IL-15. European Journal of Immunology, 38(6), pp. 1664-1676. (doi: 10.1002/eji.200838190)

Kewin, P., Kurowska-Stolarska, M. , Murphy, G., Pitman, N., ChooKang, B., Patel, M., Xu, D., Liew, F.Y. and Thomson, N. (2008) IL-33 is sufficient to induce eosinophilic airway inflammation, and exacerbates established inflammation, through increased local Th2 cytokine and chemokine production. In: Scottish Thoracic Society Meeting, Stirling, UK, 26 Oct 2007, p. 50. (doi: 10.1258/rsmsmj.53.2.48)

Raggatt, L. J., Qin, L., Tamasi, J., Jefcoat, Jr, S. C., Shimizu, E., Selvamurugan, N., Liew, F. Y., Bevelock, L., Feyen, J. H. M. and Partridge, N. C. (2008) Interleukin-18 is regulated by parathyroid hormone and is required for its bone anabolic actions. Journal of Biological Chemistry, 283(11), pp. 6790-6798. (doi: 10.1074/jbc.M709909200)

Humphreys, N. E., Xu, D., Hepworth, M. R., Liew, F. Y. and Grencis, R. K. (2008) IL-33, a potent inducer of adaptive immunity to intestinal nematodes. Journal of Immunology, 180(4), pp. 2443-2449.

Antonopoulos, C., Cumberbatch, M., Mee, J. B., Dearman, R. J., Wei, X.-Q., Liew, F. Y., Kimber, I. and Groves, R. W. (2008) IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. Journal of Leukocyte Biology, 83(2), pp. 361-367. (doi: 10.1189/jlb.0604352)

Miller, A. M., Xu, D., Asquith, D. L., Denby, L., Li, Y., Sattar, N. , Baker, A. H., McInnes, I. B. and Liew, F. Y. (2008) IL-33 reduces the development of atherosclerosis. Journal of Experimental Medicine, 205(2), pp. 339-346. (doi: 10.1084/jem.20071868) (PMID:18268038) (PMCID:PMC2271006)

Verri, W., Cunha, T., Magro, D., Domingues, A., Vieira, S., Souza, G., Liew, F., Ferreira, S. and Cunha, F. (2008) Role of IL-18 in overt pain-like behaviour in mice. European Journal of Pharmacology, 588(2-3), pp. 207-212. (doi: 10.1016/j.ejphar.2008.04.010)

Verri, Jr., W. A., Guerrero, A. T. G., Fukada, S. Y., Valerio, D. A., Cunha, T. M., Xu, D., Ferreira, S. H., Liew, F. Y. and Cunha, F. Q. (2008) IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proceedings of the National Academy of Sciences of the United States of America, 105(7), pp. 2723-2728. (doi: 10.1073/pnas.0712116105)

2007

Verri, W. A., Cunha, T. M., Ferreira, S. H., Wei, X., Leung, B. P., Fraser, A., McInnes, I. B. , Liew, F. Y. and Cunha, F. Q. (2007) IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology, 37(12), pp. 3373-3380. (doi: 10.1002/eji.200737488) (PMID:17979156)

Cai, B., Hueber, A. J., Leung, B. P., Liew, F. Y., McInnes, I. B. , Niedbala, W. and Wei, X.-q. (2007) IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. European Journal of Immunology, 37(11), pp. 3021-3029. (doi: 10.1002/eji.200737810)

Komai-Koma, M., Li, Y., Liew, F. Y., McInnes, I. B. , McKenzie, A. N. J. and Xu, D. (2007) IL-33 is a chemoattractant for human Th2 cells. European Journal of Immunology, 37(10), pp. 2779-2786. (doi: 10.1002/eji.200737547) (PMID:17853410)

Niedbala, W., Cai, B., Liu, H., Pitman, N., Chang, L. and Liew, F. Y. (2007) Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25− T cells via p53, IL-2, and OX40. Proceedings of the National Academy of Sciences of the United States of America, 104(39), pp. 15478-15483. (doi: 10.1073/pnas.0703725104)

Bacal, F. et al. (2007) Locally produced survival cytokines IL-15 and IL-7 may be associated to the predominance of CD8(+) T cells at heart lesions of human chronic Chagas disease cardiomyopathy. Scandinavian Journal of Immunology, 66, pp. 362-371. (doi: 10.1111/j.1365-3083.2007.01987.x)

Verri Jr, W. A., Cunha, T. M., Parada, C. A., Poole, S., Liew, F. Y., Ferreira, S. H. and Cunha, F. Q. (2007) Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain, Behavior, and Immunity, 21(5), pp. 535-543. (doi: 10.1016/j.bbi.2006.11.005)

Amaral, F. A., Fagundes, C. T., Liew, F. Y., Souza, A. L. S., Souza, D. G., Teixeira, M. M., Vieira, A. T. and Xu, D. (2007) ST2, an IL-1R family member, attenuates inflammation and lethality after intestinal ischemia and reperfusion. Journal of Leukocyte Biology, 81, pp. 492-499. (doi: 10.1189/jlb.0606422)

Kewin, P., Kurowska-Stolarska, M. , Murphy, G., Pitman, N., ChooKang, B., Patel, M., Xu, D., Liew, F.Y. and Thomson, N. (2007) IL-33 is sufficient to induce eosinophilic airway inflammation, and exacerbates established inflammation, through increased ST2 dependent local Th2 cytokine and chemokine production. In: Winter Meeting of the British-Thoracic-Society, London, UK, 05-07 Dec 2007, A1.

2006

Verri, W.A., Cunha, T.M., Parada, C.A., Wei, X.-Q., Ferreira, S.H., Liew, F.Y. and Cunha, F.Q. (2006) IL-15 mediates immune inflammatory hypernociception by triggering a sequential release of IFN-, endothelin, and prostaglandin. Proceedings of the National Academy of Sciences of the United States of America, 103(25), pp. 9721-9725. (doi: 10.1073/pnas.0603286103)

Alfaya, T., Alves, J., da Silva, J., Ferreira, S., Liew, F. and Moreno, S. (2006) IL-12, but not IL-18, is critical to neutrophil activation and resistance to polymicrobial sepsis induced by cecal ligation and puncture. Journal of Immunology, 177, pp. 3218-3224.

Cai, B., Liew, F. and Niedbala, W. (2006) Role of nitric oxide in the regulation of T cell functions. Annals of the Rheumatic Diseases, 65, pp. 37-40. (doi: 10.1136/ard.2006.058446)

Liu, H., Komai-Koma, M., Xu, D. and Liew, F. (2006) Toll-like receptor 2 signaling modulates the functions of CD4(+)CD25(+) regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 7048-7053. (doi: 10.1073/pnas.0601554103)

2005

Al, R., Egan, C., Else, K., Goodridge, H., Harnett, M. , Harnett, W., Houston, K., Liew, F. and Marshall, F. (2005) Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62. Journal of Immunology, 174, pp. 284-293.

Baslund, B. et al. (2005) Targeting interleukin-15 in patients with rheumatoid arthritis - A proof-of-concept study. Arthritis and Rheumatism, 52, pp. 2686-2692. (doi: 10.1002/art.21249) (PMID:16142748)

Brint, E., Liew, F., O'Neill, L. and Xu, D. (2005) Negative regulation of Toll-like receptor-mediated immune responses. Nature Reviews Immunology, 5, pp. 446-458. (doi: 10.1038/nri1630)

Choo-Kang, B., Kewin, P., Liew, F., McSharry, C., Patel, M., Thomson, N. and Xu, D. (2005) Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis. European Journal of Immunology, 35, pp. 3581-3590. (doi: 10.1002/eji.200535421)

Choo-Kang, B., Kewin, P., Liew, F., McSharry, C., Patel, M., Thomson, N. and Xu, D. (2005) TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells. Journal of Immunology, 174, pp. 7558-7563.

Culshaw, S. , Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F. and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi: 10.1002/ejui.200425661) (PMID:15789357)

Komai-Koma, M., Liew, F. and Xu, D. (2005) Expression and function of Toll-like receptor on T cells. Cellular Immunology, 233, pp. 85-89. (doi: 10.1016/j.cellimm.2005.04.019)

Liew, F., Liu, H. and Xu, D. (2005) A novel negative regulator for IL-1 receptor and Toll-like receptor 4. Immunology Letters, 96, pp. 27-31. (doi: 10.1016/j.imlet.2004.07.008)

Liew, F. and McInnes, I. (2005) A fork in the pathway to inflammation and arthritis. Nature Medicine, 11(6), pp. 601-602. (doi: 10.1038/nm0605-601) (PMID:15937470)

Liew, F. and McInnes, I. (2005) Cytokine networks - towards new therapies for rheumatoid arthritis. Nature Clinical Practice Rheumatology, 1, pp. 31-39. (doi: 10.1038/ncprheum0020) (PMID:16932625)

Liew, F., Patel, M. and Xu, D. (2005) Toll-like receptor 2 signalling and inflammation. Annals of the Rheumatic Diseases, 64, pp. 104-105. (doi: 10.1136/ard.2005.042515)

McInnes, I.B. , Liew, F.Y. and Gracie, J.A. (2005) Interleukin-18: a therapeutic target in rheumatoid arthritis? Arthritis Research and Therapy(7), pp. 38-41. (doi: 10.1186/ar1497) (PMID:15642152) (PMCID:PMC1064903)

2004

Leung, B.P., Xu, D., Culshaw, S. , McInnes, I. B. and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173(1), pp. 145-150. (doi: 10.4049/jimmunol.173.1.145) (PMID:15210768)

McKay, A., Leung, B.P., McInnes, I.B. , Thomson, N.C. and Liew, F.Y. (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. Journal of Immunology, 172(5), pp. 2903-2908. (doi: 10.4049/jimmunol.172.5.2903) (PMID:14978092)

Brint, E., Dunne, A., Liew, F., Liu, H., McKenzie, A., O'Neill, L. and Xu, D. (2004) ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nature Immunology, 5, pp. 373-379. (doi: 10.1038/ni1050)

Cunha, F., Cunha, T., Ferreira, S., Liew, F., Schivo, I. and Verri, W. (2004) Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. Journal of Pharmacology and Experimental Therapeutics, 310, pp. 710-717. (doi: 10.1124/jpet.103.063990)

Goodridge, H., Harnett, M. , Harnett, W., Houston, K., Liew, F., Marshall, F. and Wilson, E. (2004) In vivo exposure of murine dendritic cell and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype. Immunology, 113, pp. 491-498. (doi: 10.1111/j.1365-2567.2004.01993.x)

Komai-Koma, M., Jones, L., Ogg, G., Xu, D. and Liew, F. (2004) TLR2 is expressed on activated T cells as a costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 3029-3034. (doi: 10.1073/pnas.0400171101)

Komai-Koma, M., Liew, F. and Xu, D. (2004) A toll for T cell costimulation. Annals of the Rheumatic Diseases, 63, pp. 76-78. (doi: 10.1136/ard.2004.028308)

Mckay, A., Komai-Koma, M., Mcleod, K., Thomson, L., Chaudhari, R., McSharry, C., Liew, F. and Thomson, N. (2004) Interleukin-18 levels in induced sputum are reduced in asthmatic and normal smokers. Clinical and Experimental Allergy, 34, pp. 904-910. (doi: 10.1111/j.1365-2222.2004.01973.x)

2003

Liew, F.Y., Wei, X.Q. and McInnes, I. B. (2003) Role of interleukin 18 in rheumatoid arthritis. Annals of the Rheumatic Diseases, 62(Suppl), ii48-ii50. (doi: 10.1136/ard.62.suppl_2.ii48) (PMID:14532149) (PMCID:PMC1766738)

McInnes, I. B. , Gracie, J.A., Harnett, M. , Harnett, W. and Liew, F.Y. (2003) New strategies to control inflammatory synovitis: interleukin 15 and beyond. Annals of the Rheumatic Diseases, 62(2), pp. 51-54. (doi: 10.1136/ard.62.suppl_2.ii51) (PMID:14532150) (PMCID:PMC1766739)

McInnes, I. B. , Leung, B.P., Harnett, M. , Gracie, J.A., Liew, F. and Harnett, W. (2003) A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62. Journal of Immunology, 171(4), pp. 2127-2133. (doi: 10.4049/jimmunol.171.4.2127) (PMID:12902519)

Alexander, J., Campbell, C., Komai-Koma, M., Liew, F., Liu, H., McSharry, C. and Xu, D. (2003) CD4(+)CD25(+) regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. Journal of Immunology, 170, pp. 394-399.

Campbell, C. et al. (2003) A novel anti-inflammatory role for simvastatin in inflammatory arthritis. Journal of Immunology, 170, pp. 1524-1530. (doi: 10.4049/jimmunol.170.3.1524) (PMID:12538717)

Cannetti, C. O., Leung, B. P., Culshaw, S. , McInnes, I. B. , Cunha, F. Q. and Liew, F. Y. (2003) IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B-4. Journal of Immunology, 171, pp. 1009-1015. (doi: 10.4049/jimmunol.171.2.1009) (PMID:12847274)

Goodridge, H., Harnett, M. , Harnett, W. and Liew, F. (2003) Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses. Immunology, 109, pp. 415-425.

Gracie, J., Komai-Koma, M., Liew, F., McInnes, I. , Thomson, N., Wei, X. and Xu, D. (2003) Chemoattraction of human T cells by IL-18. Journal of Immunology, 170, pp. 1084-1090. (doi: 10.4049/jimmunol.170.2.1084) (PMID:12517977)

Hu, B., Liew, F., Liu, H. and Xu, D. (2003) CD4+CD25+ regulatory T cells cure murine colitis: The role of IL-10, TGF-beta, and CTLA4. Journal of Immunology, 171, pp. 5012-5017.

Liew, F. (2003) The role of innate cytokines in inflammatory response. Immunology Letters, 85, pp. 131-134.

Liew, F., Lukic, M., Mensah-Brown, E., Shahin, A. and Wei, X. (2003) Lack of the mediators of innate immunity attenuate the development of autoimmune diabetes in mice. Journal of Autoimmunity, 21, pp. 239-246. (doi: 10.1016/S0896-8411(03)00115-X)

2002

Biron, C., Caligiuri, M., Dalod, M., Durbin, J., Liew, F., Nguyen, K., Salazar-Mather, T., Van Deusen, J. and Wei, X. (2002) Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. Journal of Immunology, 169, pp. 4279-4287.

Campbell, C., Hume, D., Liew, F., McDonald, R., Sester, D., Stacey, K., Sweet, M. and Xu, D. (2002) Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. Journal of Immunology, 168, pp. 392-399.

Chiodoni, C., Colombo, M., Gallo, E., Gri, G., Liew, F. and Stoppacciaro, A. (2002) Antitumor effect of interleukin (IL)-12 in the absence of endogenous IFN-gamma: A role for intrinsic tumor immunogenicity and IL-15. Cancer Research, 62, pp. 4390-4397.

Hirahashi, J., Kelley, V., Lebedeva, T., Liew, F., Maron, R., Salant, D. and Shinozaki, M. (2002) IL-15, a survival factor for kidney epithelial cells, counteracts apoptosis and inflammation during nephritis. Journal of Clinical Investigation, 109, pp. 951-960.

Inoue, K., Ito, S., Kitano, T., Liew, F., Nishizawa, M., Okumura, T. and Seki, T. (2002) Altered response to inflammatory cytokines in hepatic energy metabolism in inducible nitric oxide synthase knockout mice. Journal of Hepatology, 36, pp. 759-765.

Khan, I., Liew, F., Moretto, M., Schwartzman, J., Wei, X. and Williams, M. (2002) Treatment with soluble interleukin-15R alpha exacerbates intracellular parasitic infection by blocking the development of memory CD8(+) T cell response. Journal of Experimental Medicine, 195, pp. 1463-1470. (doi: 10.1084/jem.20011915)

Leung, B., Conacher, M., Hunter, D., McInnes, I. , Liew, F. and Brewer, J. (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169, pp. 7071-7077. (doi: 0.4049/jimmunol.169.12.7071) (PMID:12471143)

Liew, F. (2002) T(H)1 and T(H)2 cells: a historical perspective. Nature Reviews Immunology, 2(1), pp. 55-60.

Liew, F. and McInnes, I. (2002) The role of innate mediators in inflammatory response. Molecular Immunology, 38, pp. 887-890. (doi: 10.1016/S0161-5890(02)00014-7) (PMID:12009565)

Liew, F. and McInnes, I. (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Annals of the Rheumatic Diseases, 61, pp. 100-102. (doi: 10.1136/ard.61.suppl_2.ii100) (PMID:12379638) (PMCID:PMC1766710)

Liew, F., Niedbala, W. and Wei, X. (2002) IL-15 induces type 1 and type 2 CD4(+) and CD8(+) T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 simulation in vitro. European Journal of Immunology, 32, pp. 341-347.

Mulero, V., Wei, X.Q., Liew, F.Y. and Brock, J.H. (2002) Regulation of phagosomal iron release from murine macrophages by nitric oxide. Biochemical Journal, 365, pp. 127-132.

Niedbala, W., Wei, X., Campbell, C., Thomson, D., Komai-Koma, M. and Liew, F. (2002) Nitric oxide preferentially induces type 1 T cell differentiation by selectively up-regulating IL-12 receptor β2 expression via cGMP. Proceedings of the National Academy of Sciences of the United States of America, 99(25), pp. 16186-16191. (doi: 10.1073/pnas.252464599)

2001

Abouhaidar, M., Al Dhaheri, M., al Ramadi, B., Fernandez-Cabezudo, M., Liew, F., Lukic, M., Mustafa, N. and Xu, D. (2001) Influence of vector-encoded cytokines on anti-Salmonella immunity: Divergent effects of interleukin-2 and tumor necrosis factor alpha. Infection and Immunity, 69, pp. 3980-3988.

Armour, K., Armour, K., Liew, F., Ralston, S., Reid, D., van't Hof, R. and Wei, X. (2001) Activation of the inducible nitric oxide synthase pathway contributes to inflammation-induced osteoporosis by suppressing bone formation and causing osteoblast apoptosis. Arthritis and Rheumatism, 44, pp. 2790-2796.

Bach, F., Csizmadia, E., Lee, J., Liew, F., Lin, Y., Smith, N., Soares, M., Wang, N. and Xu, D. (2001) TH2 cytokines regulate gene expression and proinflammatory responses in xenografts. Transplantation Proceedings, 33, pp. 776-777.

Campbell, C., Goodridge, H., Harnett, M. , Harnett, W., Liew, F. and Wilson, E. (2001) Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae. Journal of Immunology, 167, pp. 940-945.

Campbell, C., Kang, D., Leung, B., Liew, F., Schulz, K., Sogaard, M., Sweet, M., Trajkovic, V. and Xu, D. (2001) A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of toll-like receptor 4 expression. Journal of Immunology, 166, pp. 6633-6639.

Carter, R., Chan, W., Klemenz, R., Liew, F., Sweet, M. and Xu, D. (2001) Regulation of ST2L expression on T helper (Th) type 2 cells. European Journal of Immunology, 31, pp. 2979-2985.

Chalmers, G., Komai-Koma, M., Liew, F., Mckay, A., McSharry, C., Thomson, L. and Thomson, N. (2001) Immuno-regulatory cytokines in asthma: IL-15 and IL-13 in induced sputum. Clinical and Experimental Allergy, 31, pp. 1441-1448.

Esfandiari, E., McInnes, I. , Lindop, G., Huang, F., Field, M., Komai-Koma, M., Wei, X. and Liew, F. (2001) A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. Journal of Immunology, 167, pp. 5338-5347. (doi: 10.4049/jimmunol.167.9.5338) (PMID:11673550)

Gao, B., Gracie, J., Guan, H., Leung, B., Liew, F., McInnes, I. , Niedbala, W., Orchardson, M., Paterson, G. and Wei, X. (2001) The sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. Journal of Immunology, 167, pp. 277-282.

Jiang, H., Wei, X., Niedbala, W., Lumsden, L., Liew, F. and Forrester, J. (2001) IL-18 not required for IRBP peptide-induced EAU: Studies in gene-deficient mice. Investigative Ophthalmology and Visual Science, 42, pp. 177-182.

Leung, B. P., Culshaw, S. , Gracie, J. A., Hunter, D., Canetti, C. A., Campbell, C., Cunha, F., Liew, F. Y. and McInnes, I. B. (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167, pp. 2879-2886. (doi: 10.4049/jimmunol.167.5.2879) (PMID:11509635)

McInnes, I. B. , Gracie, J. A. and Liew, F. Y. (2001) Interleukin-18: A novel cytokine in inflammatory rheumatic disease. Arthritis and Rheumatism, 44(7), pp. 1481-1483. (doi: 10.1002/1529-0131(200107)44:7<1481::AID-ART268>3.0.CO;2-1) (PMID:11465697)

Wei, X.-q., Leung, B. P., Arthur, H. M. L., Liew, F. Y. and McInnes, I. B. (2001) Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. Journal of Immunology, 166, pp. 517-521. (doi: 10.4049/jimmunol.166.1.517) (PMID:11123331)

2000

Bolton, E., Bradley, J., Liew, F., Ruchatz, H., Smith, X. and Wei, X. (2000) Selective blockade of IL-15 by soluble IL-15 receptor alpha-chain enhances cardiac allograft survival. Journal of Immunology, 165(6), pp. 3444-3450.

Leung, B., Liew, F. and McInnes, I. (2000) Cell-cell interactions in synovitis - Interactions between T lymphocytes and synovial cells. Arthritis Research, 2(5), pp. 374-378.

Smith, K., Pottage, L., Thomas, E., Leishman, A., Doig, T., Xu, D., Liew, F. and Garside, P. (2000) Th1 and Th2CD4(+) T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo. Journal of Immunology, 165(6), pp. 3136-3144.

Xu, D., Trajkovic, V., Hunter, D., Leung, B. P., Schulz, K., Gracie, J. A., McInnes, I. B. and Liew, F. Y. (2000) IL-18 induces the differentiation of Th1 or Th2 cells depending upon cytokine milieu and genetic background. European Journal of Immunology, 30(11), pp. 3147-3156. (doi: 10.1002/1521-4141(200011)30:11<3147::AID-IMMU3147>3.0.CO;2-J) (PMID:11093129)

1999

Gracie, J. A. et al. (1999) A proinflammatory role for IL-18 in rheumatoid arthritis. Journal of Clinical Investigation, 104(10), pp. 1393-1401. (doi: 10.1172/JCI7317) (PMID:10562301) (PMCID:PMC409841)

Kropf, P., Schopf, L. R., Chung, C. L., Xu, D., Liew, F. Y., Sypek, J. P. and Müller, I. (1999) Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection. European Journal of Immunology, 29(11), pp. 3621-3628. (doi: 10.1002/(SICI)1521-4141(199911)29:11<3621::AID-IMMU3621>3.0.CO;2-Z) (PMID:10556817)

Niedbala, W., Wei, X.-Q., Piedrafita, D., Xu, D. and Liew, F. Y. (1999) Effects of nitric oxide on the induction and differentiation of Th1 cells. European Journal of Immunology, 29(8), pp. 2498-2505. (doi: 10.1002/(SICI)1521-4141(199908)29:08<2498::AID-IMMU2498>3.0.CO;2-M) (PMID:10458764)

Liew, F.Y., Xu, D. and Ling Chan, W. (1999) Immune effector mechanism in parasitic infections. Immunology Letters, 65(1-2), pp. 101-104. (doi: 10.1016/S0165-2478(98)00131-X) (PMID:10065634)

Piedrafita, D. et al. (1999) Regulation of macrophage IL-12 synthesis by Leishmania phosphoglycans. European Journal of Immunology, 29(1), pp. 235-244. (doi: 10.1002/(SICI)1521-4141(199901)29:01<235::AID-IMMU235>3.0.CO;2-S) (PMID:9933105)

Piedrafita, D., Xu, D., Hunter, D., Harrison, R. A. and Liew, F. Y. (1999) Protective immune responses induced by vaccination with an expression genomic library of leishmania major. Journal of Immunology, 163(3), pp. 1467-1472. (PMID:10415048)

1998

Huang, F.-P., Niedbala, W., Wei, X.-Q., Xu, D., Feng, G.-j., Robinson, J. H., Lam, C. and Liew, F. Y. (1998) Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. European Journal of Immunology, 28(12), pp. 4062-4070. (doi: 10.1002/(SICI)1521-4141(199812)28:12<4062::AID-IMMU4062>3.0.CO;2-K) (PMID:9862342)

Xu, D., Chan, W. L., Leung, B. P., Hunter, D., Schulz, K., Carter, R. W., McInnes, I. B. , Robinson, J. H. and Liew, F. Y. (1998) Selective expression and functions of Interleukin 18 receptor on T Helper (Th) type 1 but not Th2 cells. Journal of Experimental Medicine, 188(8), pp. 1485-1492. (doi: 10.1084/jem.188.8.1485) (PMID:9782125) (PMCID:PMC2213413)

Brewer, J. M. , Tetley, L., Richmond, J., Liew, F. Y. and Alexander, J. (1998) Lipid vesicle size determines the Th1 or Th2 response to entrapped antigen. Journal of Immunology, 161(8), pp. 4000-4007. (PMID:9780169)

Huang, F.-P., Xu, D., Esfandiari, E.-O., Sands, W., Wei, X.-q. and Liew, F. Y. (1998) Cutting edge: Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated interleukin-12 synthesis, strong Th1 responses and enhanced nitric oxide production. Journal of Immunology, 160(9), pp. 4143-4147. (PMID:9574511)

Xu, D., McSorley, S. J., Tetley, L., Chatfield, S., Dougan, G., Chan, W. L., Satoskar, A., David, J. R. and Liew, F. Y. (1998) Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium. Journal of Immunology, 160(3), pp. 1285-1289. (PMID:9570545)

1997

McInnes, I. B. , Leung, B. P., Sturrock, R. D., Field, M. and Liew, F. Y. (1997) Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis. Nature Medicine, 3(2), pp. 189-195. (doi: 10.1038/nm0297-189) (PMID:9018238)

Mcsorley, S. J., Xu, D. and Liew, F.Y. (1997) Vaccine efficacy of Salmonella strains expressing glycoprotein 63 with different promoters. Infection and Immunity, 65(1), pp. 171-178. (PMID:8975908)

1996

McInnes, I. B. , Leung, B. P., Field, M., Wei, X. Q., Huang, F.-P., Sturrock, R. D., Kinninmonth, A., Weidner, J., Mumford, R. and Liew, F. Y. (1996) Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. Journal of Experimental Medicine, 184(4), pp. 1519-1524. (doi: 10.1084/jem.184.4.1519) (PMID:8879223) (PMCID:PMC2192822)

Huang, F.P., Feng, G.J., Lindop, G., Stott, D.I. and Liew, F.Y. (1996) The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. Journal of Experimental Medicine, 183(4), pp. 1447-1459.

McInnes, I. B. , Al-Mughales, J., Field, M., Leung, B. P., Huang, F.-p., Dixon, R., Sturrock, R. D., Wilkinson, P. C. and Liew, F. Y. (1996) The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis. Nature Medicine, 2(2), pp. 175-182. (doi: 10.1038/nm0296-175) (PMID:8574962)

1995

Wei, X.-q., Charles, I. G., Smith, A., Ure, J., Feng, G.-j., Huang, F.-p., Xu, D., Mullers, W., Moncada, S. and Liew, F. Y. (1995) Altered immune responses in mice lacking inducible nitric oxide synthase. Nature, 375(6530), pp. 408-411. (doi: 10.1038/375408a0) (PMID:7539113)

Xu, D. and Liew, F.Y. (1995) Protection against leishmaniasis by injection of DNA encoding a major surface glycoprotein, gp63, of L. major. Immunology, 84(2), pp. 173-176. (PMID:7750991)

Ianaro, A., Xu, D., O'Donnell, C.A. , Di Rosa, M. and Liew, F.Y. (1995) Expression of TGF-beta in attenuated Salmonella typhimurium: oral administration leads to the reduction of inflammation, IL-2 and IFN-gamma, but enhancement of IL-10, in carrageenin-induced oedema in mice. Immunology, 84(1), pp. 8-15. (PMID:7890306)

Xu, D., McSorley, S.J., Chatfield, S.N., Dougan, G. and Liew, F.Y. (1995) Protection against Leishmania major infection in genetically susceptible BALB/c mice by gp63 delivered orally in attenuated Salmonella typhimurium (AroA- AroD-). Immunology, 85(1), pp. 1-7. (PMID:7635511)

1994

Xu, D. and Liew, F.Y. (1994) Genetic vaccination against leishmaniasis. Vaccine, 12(16), pp. 1534-1536. (doi: 10.1016/0264-410X(94)90079-5) (PMID:7879420)

Taylor-Robinson, A. W., Liew, F. Y., Severn, A., Xu, D., McSorley, S. J., Garside, P. , Padron, J. and Phillips, R. S. (1994) Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells. European Journal of Immunology, 24(4), pp. 980-984. (doi: 10.1002/eji.1830240430) (PMID:8149966)

Sands, W. A., Bulut, V., Severn, A., Xu, D. and Liew, F. Y. (1994) Inhibition of nitric oxide synthesis by interleukin-4 may involve inhibiting the activation of protein kinase C epsilon. European Journal of Immunology, 24(10), pp. 2345-2350. (doi: 10.1002/eji.1830241013) (PMID:7523136)

1993

Severn, A., Xu, D., Doyle, J., Leal, L. M. C., O'Donnell, C. A. , Brett, S. J., Moss, D. W. and Liew, F. Y. (1993) Pre-exposure of murine macrophages to lipopolysaccharide inhibits the induction of nitric oxide synthase and reduces leishmanicidal activity. European Journal of Immunology, 23(7), pp. 1711-1714. (doi: 10.1002/eji.1830230747) (PMID:7686861)

Cunha, F. Q., Assreuy, J., Xu, D., Charles, I., Liew, F. Y. and Moncada, S. (1993) Repeated induction of nitric oxide synthase and leishmanicidal activity in murine macrophages. European Journal of Immunology, 23(6), pp. 1385-1388. (doi: 10.1002/eji.1830230631) (PMID:7684689)

This list was generated on Thu Dec 9 13:10:16 2021 GMT.
Number of items: 178.

Articles

Donate, P. B. et al. (2021) Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America, 118(1), e201712011. (doi: 10.1073/pnas.2017120118) (PMID:33443169) (PMCID:PMC7817209)

Akbar, M., Garcia-Melchor, E., Chilaka, S., Little, K. J., Sood, S., Reilly, J. H., Liew, F. Y., McInnes, I. B. and Millar, N. L. (2020) Attenuation of Dupuytren’s fibrosis via targeting of the STAT-1 modulated IL-13RA1 response. Science Advances, 6(28), eaaz8272. (doi: 10.1126/sciadv.aaz8272)

Colón, D. F. et al. (2019) Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis. Critical Care, 23, 113. (doi: 10.1186/s13054-019-2407-8) (PMID:30961634) (PMCID:PMC6454713)

Castanheira, F. V. e. S. et al. (2018) CCR5-positive inflammatory monocytes are crucial for control of sepsis. Shock, 52(5), e100-e106. (doi: 10.1097/SHK.0000000000001301) (PMID:30724784)

Marques, R. E., Besnard, A.-G., Maillet, I., Fagundes, C. T., Souza, D. G., Ryffel, B., Teixeira, M. M., Liew, F. Y. and Guabiraba, R. (2018) Interleukin-33 contributes to disease severity in Dengue virus infection in mice. Immunology, 155(4), pp. 477-490. (doi: 10.1111/imm.12988) (PMID:30098206)

Strangward, P. et al. (2018) Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria. Proceedings of the National Academy of Sciences of the United States of America, 115(28), pp. 7404-7409. (doi: 10.1073/pnas.1801737115) (PMID:29954866) (PMCID:PMC6048513)

Talbot, J. et al. (2018) Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells. Arthritis Research and Therapy, 20, 119. (doi: 10.1186/s13075-018-1609-9) (PMID:29884199) (PMCID:PMC5994132)

Castanheira, F. V. E. S. et al. (2018) The atypical chemokine receptor ACKR2 is protective against sepsis. Shock, 49(6), pp. 682-689. (doi: 10.1097/SHK.0000000000000969) (PMID:29589840)

Staurengo-Ferrari, L. et al. (2018) Interleukin-33 receptor (ST2) deficiency improves the outcome of Staphylococcus aureus-induced septic arthritis. Frontiers in Immunology, 9, (doi: 10.3389/fimmu.2018.00962) (PMID:29867945) (PMCID:PMC5968393)

Peres, R. S. et al. (2018) TGF-β signalling defect is linked to low CD39 expression on regulatory T cells and methotrexate resistance in rheumatoid arthritis. Journal of Autoimmunity, (doi: 10.1016/j.jaut.2018.01.004) (PMID:29426578)

Cole, S. L. et al. (2017) M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. JCI Insight, 2(7), e91868. (doi: 10.1172/jci.insight.91868) (PMID:28405622) (PMCID:PMC5374077)

Nascimento, D. C. et al. (2017) IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nature Communications, 8, 14919. (doi: 10.1038/ncomms14919) (PMID:28374774) (PMCID:PMC5382289)

Liew, F. Y., Girard, J.-P. and Turnquist, H. R. (2016) Interleukin-33 in health and disease. Nature Reviews Immunology, 16(11), pp. 676-689. (doi: 10.1038/nri.2016.95) (PMID:27640624)

Zarpelon, A. C. et al. (2016) Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB Journal, 30(1), pp. 54-65. (doi: 10.1096/fj.14-267146) (PMID:26310268)

Fu, A. K. Y. et al. (2016) IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline. Proceedings of the National Academy of Sciences of the United States of America, 113(19), E2705-E2713. (doi: 10.1073/pnas.1604032113) (PMID:27091974) (PMCID:PMC4868478)

Malcolm, J. et al. (2015) IL-33 exacerbates periodontal disease through induction of RANKL. Journal of Dental Research, 94(7), pp. 968-975. (doi: 10.1177/0022034515577815) (PMID:25808546)

Millar, N. L. , Gilchrist, D., Akbar, M., Reilly, J. H., Kerr, S. C., Campbell, A. L., Murrell, G. A.C., Liew, F. Y., Kurowska-Stolarska, M. and McInnes, I. B. (2015) MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease. Nature Communications, 6, 6774. (doi: 10.1038/ncomms7774) (PMID:25857925) (PMCID:PMC4403384)

Liew, F. Y. (2015) Cigarette smoke resets the alarmin IL-33 in COPD. Immunity, 42(3), pp. 401-403. (doi: 10.1016/j.immuni.2015.02.014) (PMID:25786171)

Besnard, A.-G., Guabiraba Brito, R., Niedbala, W., Palomo, J., Reverchon, F., Shaw, T. N., Couper, K. N., Ryffel, B. and Liew, F. (2015) IL-33-mediated protection against experimental cerebral malaria is linked to induction of Type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. PLoS Pathogens, 11(2), e1004607. (doi: 10.1371/journal.ppat.1004607) (PMID:25659095) (PMCID:PMC4450060)

Peres, R. S. et al. (2015) Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America, 112(8), pp. 2509-2514. (doi: 10.1073/pnas.1424792112) (PMID:25675517)

Li, D. et al. (2014) IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice. Journal of Allergy and Clinical Immunology, 134(6), 1422-1432.e11. (doi: 10.1016/j.jaci.2014.05.011) (PMID:24985397) (PMCID:PMC4258609)

Barbour, M. et al. (2014) IL-33 attenuates the development of experimental autoimmune uveitis. European Journal of Immunology, 44(11), pp. 3320-3329. (doi: 10.1002/eji.201444671) (PMID:25116404) (PMCID:PMC4449115)

Sattler, S. et al. (2014) IL-10-producing regulatory B cells induced by IL-33 (BregIL-33) effectively attenuate mucosal inflammatory responses in the gut. Journal of Autoimmunity, 50, pp. 107-122. (doi: 10.1016/j.jaut.2014.01.032) (PMID:24491821) (PMCID:PMC4012142)

Mirchandani, A. S., Besnard, A.-G., Yip, E., Scott, C., Bain, C. C., Cerovic, V., Salmond, R. J. and Liew, F. J. (2014) Type 2 innate lymphoid cells drive CD4+ Th2 cell responses. Journal of Immunology, 192(5), pp. 2442-2448. (doi: 10.4049/jimmunol.1300974)

Guabiraba Brito, R. et al. (2014) IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunology, 7(5), pp. 1079-1093. (doi: 10.1038/mi.2013.124)

Niedbala, W. et al. (2014) Nitric oxide enhances Th9 cell differentiation and airway inflammation. Nature Communications, 5(4575), (doi: 10.1038/ncomms5575)

Gabriele, L. et al. (2013) Novel allergic asthma model demonstrates ST2-dependent dendritic cell targeting by cypress pollen. Journal of Allergy and Clinical Immunology, 132(3), 686-695.e7. (doi: 10.1016/j.jaci.2013.02.037)

Magro, D.A.C., Hohmann, M.S.N., Mizokami, S.S., Cunha, T.M., Alves-Filho, J.C., Casagrande, R., Ferreira, S.H., Liew, F.Y., Cunha, F.Q. and Verri Jr, W.A. (2013) An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice. Brazilian Journal of Medical and Biological Research, 46(7), pp. 601-606. (doi: 10.1590/1414-431x20132894) (PMID:23903682) (PMCID:PMC3859337)

Niedbala, W., Besnard, A.-G., Jiang, H.-R., Alves-Filho, J.C., Fukada, S.Y., Nascimento, D., Mitani, A., Pushparaj, P., Alqahtani, M.H. and Liew, F.Y. (2013) Nitric oxide-induced regulatory T cells inhibit Th17 but not Th1 cell differentiation and function. Journal of Immunology, 191(1), pp. 164-170. (doi: 10.4049/jimmunol.1202580)

Zarpelon, A.C., Cunha, T.M., Alves-Filho, J.C., Pinto, L.G., Ferreira, S.H., McInnes, I.B. , Xu, D., Liew, F.Y., Cunha, F.Q. and Verri, W.A. (2013) IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2. British Journal of Pharmacology, 169(1), pp. 90-101. (doi: 10.1111/bph.12110) (PMID:23347081) (PMCID:PMC3632241)

Salmond, R.J., Mirchandani, A.S., Besnard, A.-G., Bain, C.C., Thomson, N.C. and Liew, F.Y. (2012) IL-33 induces innate lymphoid cell–mediated airway inflammation by activating mammalian target of rapamycin. Journal of Allergy and Clinical Immunology, 130(5), pp. 1159-1166. (doi: 10.1016/j.jaci.2012.05.018)

Komai-Koma, M. et al. (2012) Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice. Allergy, 67(9), pp. 1118-1126. (doi: 10.1111/j.1398-9995.2012.02859.x) (PMID:22702477) (PMCID:PMC3660789)

Jiang, H.-R. et al. (2012) IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages. European Journal of Immunology, 42(7), pp. 1804-1814. (doi: 10.1002/eji.201141947)

Liew, F.Y. (2012) IL-33: a Janus cytokine. Annals of the Rheumatic Diseases, 71(Sup. 2), i101-i104. (doi: 10.1136/annrheumdis-2011-200589)

Mirchandani, A. S., Salmond, R. J. and Liew, F. Y. (2012) Interleukin-33 and the function of innate lymphoid cells. Trends in Immunology, 33(8), pp. 389-396. (doi: 10.1016/j.it.2012.04.005)

Turnquist, H. R. et al. (2011) IL-33 expands suppressive CD11b+ Gr-1int and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. Journal of Immunology, 187(9), pp. 4598-4610. (doi: 10.4049/jimmunol.1100519)

Hueber, A. J., Alves-Filho, J. C., Asquith, D. L., Michels, C., Millar, N. L. , Reilly, J. H., Graham, G. J. , Liew, F. Y., Miller, A. M. and McInnes, I. B. (2011) IL-33 induces skin inflammation with mast cell and neutrophil activation. European Journal of Immunology, 41(8), pp. 2229-2237. (doi: 10.1002/eji.201041360) (PMID:21674479)

Miller, A. M. and Liew, F. Y. (2011) The IL-33/ST2 pathway — A new therapeutic target in cardiovascular disease. Pharmacology and Therapeutics, 131(2), pp. 179-186. (doi: 10.1016/j.pharmthera.2011.02.005)

Kurowska-Stolarska, M. et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11193-11198. (doi: 10.1073/pnas.1019536108) (PMID:21690378)

Zaiss, M. M. et al. (2011) IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-α–mediated bone loss. Journal of Immunology, 186(11), pp. 6097-6105. (doi: 10.4049/jimmunol.1003487) (PMID:21515798)

Niedbala, W., Alves-Filho, J. C., Fukada, S. Y., Vieira, S. M., Mitani, A., Sonego, F., Mirchandani, A., Nascimento, D. C., Cunha, F. Q. and Liew, F. Y. (2011) Regulation of type 17 helper T-cell function by nitric oxide during inflammation. Proceedings of the National Academy of Sciences of the United States of America, 108(22), pp. 9220-9225. (doi: 10.1073/pnas.1100667108)

Culshaw, S. , McInnes, I. B. and Liew, F. Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38(S11), pp. 106-113. (doi: 10.1111/j.1600-051X.2010.01669.x) (PMID:21323707)

Kinane, D. F. et al. (2011) Host-response: understanding the cellular and molecular mechanisms of host-microbial interactions - consensus of the Seventh European Workshop on Periodontology. Journal of Clinical Periodontology, 38(S11), pp. 44-48. (doi: 10.1111/j.1600-051X.2010.01682.x)

Komai-Koma, M., Gilchrist, D. S., McKenzie, A. N. J., Goodyear, C. S. , Xu, D. and Liew, F. Y. (2011) IL-33 activates B1 cells and exacerbates contact sensitivity. Journal of Immunology, 186(4), pp. 2584-2591. (doi: 10.4049/jimmunol.1002103)

Pitman, N., Asquith, D.L., Murphy, G., Liew, F.Y. and McInnes, I.B. (2011) Collagen-induced arthritis is not impaired in mast cell-deficient mice. Annals of the Rheumatic Diseases, 70(6), pp. 1170-1171. (doi: 10.1136/ard.2010.134528) (PMID:21131642)

Stolarski, B., Kurowska-Stolarska, M. , Kewin, P., Xu, D. and Liew, F. Y. (2010) IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation. Journal of Immunology, 185(6), pp. 3472-3480. (doi: 10.4049/jimmunol.1000730)

Miller, A. M., Asquith, D. L., Hueber, A. J., Anderson, L. A., Holmes, W. M. , McKenzie, A. N., Xu, D., Sattar, N. , McInnes, I. B. and Liew, F. Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107(5), pp. 650-658. (doi: 10.1161/CIRCRESAHA.110.218867) (PMID:20634488) (PMCID:PMC4254700)

Verri, W. A. et al. (2010) IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases, 69(9), pp. 1697-1703. (doi: 10.1136/ard.2009.122655) (PMID:20472598)

McLaren, J. E., Michael, D. R., Salter, R. C., Ashlin, T. G., Calder, C. J., Miller, A. M., Liew, F. Y. and Ramji, D. P. (2010) IL-33 Reduces Macrophage Foam Cell Formation. Journal of Immunology, 185(2), pp. 1222-1229. (doi: 10.4049/jimmunol.1000520)

Xu, D. et al. (2010) IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology, 184(5), pp. 2620-2626. (doi: 10.4049/jimmunol.0902685) (PMID:20139274)

Asquith, D. L., Miller, A. M., Hueber, A. J., Liew, F. Y., Sattar, N. and McInnes, I. B. (2010) Apolipoprotein E-deficient mice are resistant to the development of collagen-induced arthritis. Arthritis and Rheumatism, 62(2), pp. 472-477. (doi: 10.1002/art.27205) (PMID:20112375)

Liew, F. Y., Pitman, N. I. and McInnes, I. B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature Reviews Immunology, 10(2), pp. 103-110. (doi: 10.1038/nri2692) (PMID:20081870)

Alves Filho, J. C. et al. (2010) Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection. Nature Medicine, 16(6), pp. 708-712. (doi: 10.1038/nm.2156)

Murphy, G.E.J., Xu, D., Liew, F.Y. and McInnes, I.B. (2010) Role of interleukin 33 in human immunopathology. Annals of the Rheumatic Diseases, 69(Suppl), pp. 43-47. (doi: 10.1136/ard.2009.120113) (PMID:19995743)

Kurowska-Stolarska, M. et al. (2009) IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation. Journal of Immunology, 183(10), pp. 6469-6477. (doi: 10.4049/jimmunol.0901575) (PMID:19841166)

Asquith, D. L., Miller, A. M., McInnes, I. B. and Liew, F. Y. (2009) Animal models of rheumatoid arthritis. European Journal of Immunology, 39(8), pp. 2040-2044. (doi: 10.1002/eji.200939578) (PMID:19672892)

Pushparaj, P. N., Tay, H. K., H'Ng, S. C., Pitman, N., Xu, D., McKenzie, A., Liew, F. Y. and Melendez, A. J. (2009) The cytokine interleukin-33 mediates anaphylactic shock. Proceedings of the National Academy of Sciences of the United States of America, 106(24), pp. 9773-9778. (doi: 10.1073/pnas.0901206106)

McKimmie, C. S. et al. (2009) A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. Blood, 113(18), pp. 4224-4231. (doi: 10.1182/blood-2008-08-174698) (PMID:19202130)

Lemos, H. P. et al. (2009) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ  production. Proceedings of the National Academy of Sciences of the United States of America, 106(14), pp. 5954-5959. (doi: 10.1073/pnas.0812782106) (PMID:19289819)

Trieu, A., Bokil, N., Dunn, J. A., Roberts, T. L., Xu, D., Liew, F. Y., Hume, D. A., Stacey, K. J. and Sweet, M. J. (2009) TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium. Immunology and Cell Biology, 87(3), pp. 218-225. (doi: 10.1038/icb.2008.95)

Jiang, H., Al Rasebi, Z., Mensah-Brown, E., Shahin, A., Xu, D., Goodyear, C. , Fukada, S., Liu, F., Liew, F. and Lukic, M. (2009) Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis. Journal of Immunology, 182(2), pp. 1167-1173.

Asquith, D.L., Miller, A.L., McInnes, I.B. and Liew, F.Y. (2009) Autoimmune disease: rheumatoid arthritis. Animal models of rheumatoid arthritis. European Journal of Immunology, 39, pp. 1991-2058.

Kurowska-Stolarska, M. et al. (2008) IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4. Journal of Immunology, 181(7), pp. 4780-4790.

Niedbala, W., Cai, B., Wei, X., Patakas, A., Leung, B. P., McInnes, I. and Liew, F. Y. (2008) Interleukin 27 attenuates collagen-induced arthritis. Annals of the Rheumatic Diseases, 67(10), pp. 1474-1479. (doi: 10.1136/ard.2007.083360) (PMID:18199596)

McKimmie, C. S. et al. (2008) Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of Immunology, 181(5), pp. 3353-3363. (doi: 10.4049/jimmunol.181.11.8170-a) (PMID:19039854)

Xu, D. et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proceedings of the National Academy of Sciences of the United States of America, 105(31), pp. 10913-10918. (doi: 10.1073/pnas.0801898105) (PMID:18667700) (PMCID:PMC2491487)

Grespan, R., Fukada, S. Y., Lemos, H. P., Vieira, S. M., Napimoga, M. H., Teixeira, M. M., Fraser, A. R., Liew, F. Y., McInnes, I. B. and Cunha, F. Q. (2008) CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis. Arthritis and Rheumatism, 58(7), pp. 2030-2040. (doi: 10.1002/art.23597) (PMID:18576322)

Turnquist, H. R., Sumpter, T. L., Tsung, A., Zahorchak, A. F., Nakao, A., Nau, G. J., Liew, F. Y., Geller, D. A. and Thomson, A. W. (2008) IL-1 β-driven ST2L express ion promotes maturation resistance in rapamycin-conditioned dendritic cells. Journal of Immunology, 181(1), pp. 62-72.

Turnquist, H. R., Sumpter, T. L., Tsung, A., Zahorchak, A. F., Nakao, A., Nau, G. J., Liew, F. Y., Geller, D. A. and Thomson, A. W. (2008) IL-1β-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells. Journal of Immunology, 181(1), pp. 62-72. (doi: 10.4049/jimmunol.181.1.62)

Yang, C.-H., Tian, L., Ling, G.-S., Trendell‐Smith, N. J., Ma, L., Lo, C.-K., Stott, D. I., Liew, F. Y. and Huang, F.-P. (2008) Correction: Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: Roles of IL‐2versusIL‐15. European Journal of Immunology, 38(7), p. 2046. (doi: 10.1002/eji.200890028)

Yang, C.-H., Tian, L., Ling, G.-S., Trendell-Smith, N. J., Ma, L., Lo, C.-K., Stott, D. I., Liew, F. Y. and Huang, F.-P. (2008) Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: Roles of IL-2 versus IL-15. European Journal of Immunology, 38(6), pp. 1664-1676. (doi: 10.1002/eji.200838190)

Raggatt, L. J., Qin, L., Tamasi, J., Jefcoat, Jr, S. C., Shimizu, E., Selvamurugan, N., Liew, F. Y., Bevelock, L., Feyen, J. H. M. and Partridge, N. C. (2008) Interleukin-18 is regulated by parathyroid hormone and is required for its bone anabolic actions. Journal of Biological Chemistry, 283(11), pp. 6790-6798. (doi: 10.1074/jbc.M709909200)

Humphreys, N. E., Xu, D., Hepworth, M. R., Liew, F. Y. and Grencis, R. K. (2008) IL-33, a potent inducer of adaptive immunity to intestinal nematodes. Journal of Immunology, 180(4), pp. 2443-2449.

Antonopoulos, C., Cumberbatch, M., Mee, J. B., Dearman, R. J., Wei, X.-Q., Liew, F. Y., Kimber, I. and Groves, R. W. (2008) IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. Journal of Leukocyte Biology, 83(2), pp. 361-367. (doi: 10.1189/jlb.0604352)

Miller, A. M., Xu, D., Asquith, D. L., Denby, L., Li, Y., Sattar, N. , Baker, A. H., McInnes, I. B. and Liew, F. Y. (2008) IL-33 reduces the development of atherosclerosis. Journal of Experimental Medicine, 205(2), pp. 339-346. (doi: 10.1084/jem.20071868) (PMID:18268038) (PMCID:PMC2271006)

Verri, W., Cunha, T., Magro, D., Domingues, A., Vieira, S., Souza, G., Liew, F., Ferreira, S. and Cunha, F. (2008) Role of IL-18 in overt pain-like behaviour in mice. European Journal of Pharmacology, 588(2-3), pp. 207-212. (doi: 10.1016/j.ejphar.2008.04.010)

Verri, Jr., W. A., Guerrero, A. T. G., Fukada, S. Y., Valerio, D. A., Cunha, T. M., Xu, D., Ferreira, S. H., Liew, F. Y. and Cunha, F. Q. (2008) IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proceedings of the National Academy of Sciences of the United States of America, 105(7), pp. 2723-2728. (doi: 10.1073/pnas.0712116105)

Verri, W. A., Cunha, T. M., Ferreira, S. H., Wei, X., Leung, B. P., Fraser, A., McInnes, I. B. , Liew, F. Y. and Cunha, F. Q. (2007) IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology, 37(12), pp. 3373-3380. (doi: 10.1002/eji.200737488) (PMID:17979156)

Cai, B., Hueber, A. J., Leung, B. P., Liew, F. Y., McInnes, I. B. , Niedbala, W. and Wei, X.-q. (2007) IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. European Journal of Immunology, 37(11), pp. 3021-3029. (doi: 10.1002/eji.200737810)

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Niedbala, W., Cai, B., Liu, H., Pitman, N., Chang, L. and Liew, F. Y. (2007) Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25− T cells via p53, IL-2, and OX40. Proceedings of the National Academy of Sciences of the United States of America, 104(39), pp. 15478-15483. (doi: 10.1073/pnas.0703725104)

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Verri Jr, W. A., Cunha, T. M., Parada, C. A., Poole, S., Liew, F. Y., Ferreira, S. H. and Cunha, F. Q. (2007) Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain, Behavior, and Immunity, 21(5), pp. 535-543. (doi: 10.1016/j.bbi.2006.11.005)

Amaral, F. A., Fagundes, C. T., Liew, F. Y., Souza, A. L. S., Souza, D. G., Teixeira, M. M., Vieira, A. T. and Xu, D. (2007) ST2, an IL-1R family member, attenuates inflammation and lethality after intestinal ischemia and reperfusion. Journal of Leukocyte Biology, 81, pp. 492-499. (doi: 10.1189/jlb.0606422)

Verri, W.A., Cunha, T.M., Parada, C.A., Wei, X.-Q., Ferreira, S.H., Liew, F.Y. and Cunha, F.Q. (2006) IL-15 mediates immune inflammatory hypernociception by triggering a sequential release of IFN-, endothelin, and prostaglandin. Proceedings of the National Academy of Sciences of the United States of America, 103(25), pp. 9721-9725. (doi: 10.1073/pnas.0603286103)

Alfaya, T., Alves, J., da Silva, J., Ferreira, S., Liew, F. and Moreno, S. (2006) IL-12, but not IL-18, is critical to neutrophil activation and resistance to polymicrobial sepsis induced by cecal ligation and puncture. Journal of Immunology, 177, pp. 3218-3224.

Cai, B., Liew, F. and Niedbala, W. (2006) Role of nitric oxide in the regulation of T cell functions. Annals of the Rheumatic Diseases, 65, pp. 37-40. (doi: 10.1136/ard.2006.058446)

Liu, H., Komai-Koma, M., Xu, D. and Liew, F. (2006) Toll-like receptor 2 signaling modulates the functions of CD4(+)CD25(+) regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 7048-7053. (doi: 10.1073/pnas.0601554103)

Al, R., Egan, C., Else, K., Goodridge, H., Harnett, M. , Harnett, W., Houston, K., Liew, F. and Marshall, F. (2005) Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62. Journal of Immunology, 174, pp. 284-293.

Baslund, B. et al. (2005) Targeting interleukin-15 in patients with rheumatoid arthritis - A proof-of-concept study. Arthritis and Rheumatism, 52, pp. 2686-2692. (doi: 10.1002/art.21249) (PMID:16142748)

Brint, E., Liew, F., O'Neill, L. and Xu, D. (2005) Negative regulation of Toll-like receptor-mediated immune responses. Nature Reviews Immunology, 5, pp. 446-458. (doi: 10.1038/nri1630)

Choo-Kang, B., Kewin, P., Liew, F., McSharry, C., Patel, M., Thomson, N. and Xu, D. (2005) Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis. European Journal of Immunology, 35, pp. 3581-3590. (doi: 10.1002/eji.200535421)

Choo-Kang, B., Kewin, P., Liew, F., McSharry, C., Patel, M., Thomson, N. and Xu, D. (2005) TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells. Journal of Immunology, 174, pp. 7558-7563.

Culshaw, S. , Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F. and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi: 10.1002/ejui.200425661) (PMID:15789357)

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Liew, F. and McInnes, I. (2005) Cytokine networks - towards new therapies for rheumatoid arthritis. Nature Clinical Practice Rheumatology, 1, pp. 31-39. (doi: 10.1038/ncprheum0020) (PMID:16932625)

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Leung, B.P., Xu, D., Culshaw, S. , McInnes, I. B. and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173(1), pp. 145-150. (doi: 10.4049/jimmunol.173.1.145) (PMID:15210768)

McKay, A., Leung, B.P., McInnes, I.B. , Thomson, N.C. and Liew, F.Y. (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. Journal of Immunology, 172(5), pp. 2903-2908. (doi: 10.4049/jimmunol.172.5.2903) (PMID:14978092)

Brint, E., Dunne, A., Liew, F., Liu, H., McKenzie, A., O'Neill, L. and Xu, D. (2004) ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nature Immunology, 5, pp. 373-379. (doi: 10.1038/ni1050)

Cunha, F., Cunha, T., Ferreira, S., Liew, F., Schivo, I. and Verri, W. (2004) Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. Journal of Pharmacology and Experimental Therapeutics, 310, pp. 710-717. (doi: 10.1124/jpet.103.063990)

Goodridge, H., Harnett, M. , Harnett, W., Houston, K., Liew, F., Marshall, F. and Wilson, E. (2004) In vivo exposure of murine dendritic cell and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype. Immunology, 113, pp. 491-498. (doi: 10.1111/j.1365-2567.2004.01993.x)

Komai-Koma, M., Jones, L., Ogg, G., Xu, D. and Liew, F. (2004) TLR2 is expressed on activated T cells as a costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 3029-3034. (doi: 10.1073/pnas.0400171101)

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Mckay, A., Komai-Koma, M., Mcleod, K., Thomson, L., Chaudhari, R., McSharry, C., Liew, F. and Thomson, N. (2004) Interleukin-18 levels in induced sputum are reduced in asthmatic and normal smokers. Clinical and Experimental Allergy, 34, pp. 904-910. (doi: 10.1111/j.1365-2222.2004.01973.x)

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McInnes, I. B. , Gracie, J.A., Harnett, M. , Harnett, W. and Liew, F.Y. (2003) New strategies to control inflammatory synovitis: interleukin 15 and beyond. Annals of the Rheumatic Diseases, 62(2), pp. 51-54. (doi: 10.1136/ard.62.suppl_2.ii51) (PMID:14532150) (PMCID:PMC1766739)

McInnes, I. B. , Leung, B.P., Harnett, M. , Gracie, J.A., Liew, F. and Harnett, W. (2003) A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62. Journal of Immunology, 171(4), pp. 2127-2133. (doi: 10.4049/jimmunol.171.4.2127) (PMID:12902519)

Alexander, J., Campbell, C., Komai-Koma, M., Liew, F., Liu, H., McSharry, C. and Xu, D. (2003) CD4(+)CD25(+) regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. Journal of Immunology, 170, pp. 394-399.

Campbell, C. et al. (2003) A novel anti-inflammatory role for simvastatin in inflammatory arthritis. Journal of Immunology, 170, pp. 1524-1530. (doi: 10.4049/jimmunol.170.3.1524) (PMID:12538717)

Cannetti, C. O., Leung, B. P., Culshaw, S. , McInnes, I. B. , Cunha, F. Q. and Liew, F. Y. (2003) IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B-4. Journal of Immunology, 171, pp. 1009-1015. (doi: 10.4049/jimmunol.171.2.1009) (PMID:12847274)

Goodridge, H., Harnett, M. , Harnett, W. and Liew, F. (2003) Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses. Immunology, 109, pp. 415-425.

Gracie, J., Komai-Koma, M., Liew, F., McInnes, I. , Thomson, N., Wei, X. and Xu, D. (2003) Chemoattraction of human T cells by IL-18. Journal of Immunology, 170, pp. 1084-1090. (doi: 10.4049/jimmunol.170.2.1084) (PMID:12517977)

Hu, B., Liew, F., Liu, H. and Xu, D. (2003) CD4+CD25+ regulatory T cells cure murine colitis: The role of IL-10, TGF-beta, and CTLA4. Journal of Immunology, 171, pp. 5012-5017.

Liew, F. (2003) The role of innate cytokines in inflammatory response. Immunology Letters, 85, pp. 131-134.

Liew, F., Lukic, M., Mensah-Brown, E., Shahin, A. and Wei, X. (2003) Lack of the mediators of innate immunity attenuate the development of autoimmune diabetes in mice. Journal of Autoimmunity, 21, pp. 239-246. (doi: 10.1016/S0896-8411(03)00115-X)

Biron, C., Caligiuri, M., Dalod, M., Durbin, J., Liew, F., Nguyen, K., Salazar-Mather, T., Van Deusen, J. and Wei, X. (2002) Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. Journal of Immunology, 169, pp. 4279-4287.

Campbell, C., Hume, D., Liew, F., McDonald, R., Sester, D., Stacey, K., Sweet, M. and Xu, D. (2002) Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. Journal of Immunology, 168, pp. 392-399.

Chiodoni, C., Colombo, M., Gallo, E., Gri, G., Liew, F. and Stoppacciaro, A. (2002) Antitumor effect of interleukin (IL)-12 in the absence of endogenous IFN-gamma: A role for intrinsic tumor immunogenicity and IL-15. Cancer Research, 62, pp. 4390-4397.

Hirahashi, J., Kelley, V., Lebedeva, T., Liew, F., Maron, R., Salant, D. and Shinozaki, M. (2002) IL-15, a survival factor for kidney epithelial cells, counteracts apoptosis and inflammation during nephritis. Journal of Clinical Investigation, 109, pp. 951-960.

Inoue, K., Ito, S., Kitano, T., Liew, F., Nishizawa, M., Okumura, T. and Seki, T. (2002) Altered response to inflammatory cytokines in hepatic energy metabolism in inducible nitric oxide synthase knockout mice. Journal of Hepatology, 36, pp. 759-765.

Khan, I., Liew, F., Moretto, M., Schwartzman, J., Wei, X. and Williams, M. (2002) Treatment with soluble interleukin-15R alpha exacerbates intracellular parasitic infection by blocking the development of memory CD8(+) T cell response. Journal of Experimental Medicine, 195, pp. 1463-1470. (doi: 10.1084/jem.20011915)

Leung, B., Conacher, M., Hunter, D., McInnes, I. , Liew, F. and Brewer, J. (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169, pp. 7071-7077. (doi: 0.4049/jimmunol.169.12.7071) (PMID:12471143)

Liew, F. (2002) T(H)1 and T(H)2 cells: a historical perspective. Nature Reviews Immunology, 2(1), pp. 55-60.

Liew, F. and McInnes, I. (2002) The role of innate mediators in inflammatory response. Molecular Immunology, 38, pp. 887-890. (doi: 10.1016/S0161-5890(02)00014-7) (PMID:12009565)

Liew, F. and McInnes, I. (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Annals of the Rheumatic Diseases, 61, pp. 100-102. (doi: 10.1136/ard.61.suppl_2.ii100) (PMID:12379638) (PMCID:PMC1766710)

Liew, F., Niedbala, W. and Wei, X. (2002) IL-15 induces type 1 and type 2 CD4(+) and CD8(+) T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 simulation in vitro. European Journal of Immunology, 32, pp. 341-347.

Mulero, V., Wei, X.Q., Liew, F.Y. and Brock, J.H. (2002) Regulation of phagosomal iron release from murine macrophages by nitric oxide. Biochemical Journal, 365, pp. 127-132.

Niedbala, W., Wei, X., Campbell, C., Thomson, D., Komai-Koma, M. and Liew, F. (2002) Nitric oxide preferentially induces type 1 T cell differentiation by selectively up-regulating IL-12 receptor β2 expression via cGMP. Proceedings of the National Academy of Sciences of the United States of America, 99(25), pp. 16186-16191. (doi: 10.1073/pnas.252464599)

Abouhaidar, M., Al Dhaheri, M., al Ramadi, B., Fernandez-Cabezudo, M., Liew, F., Lukic, M., Mustafa, N. and Xu, D. (2001) Influence of vector-encoded cytokines on anti-Salmonella immunity: Divergent effects of interleukin-2 and tumor necrosis factor alpha. Infection and Immunity, 69, pp. 3980-3988.

Armour, K., Armour, K., Liew, F., Ralston, S., Reid, D., van't Hof, R. and Wei, X. (2001) Activation of the inducible nitric oxide synthase pathway contributes to inflammation-induced osteoporosis by suppressing bone formation and causing osteoblast apoptosis. Arthritis and Rheumatism, 44, pp. 2790-2796.

Bach, F., Csizmadia, E., Lee, J., Liew, F., Lin, Y., Smith, N., Soares, M., Wang, N. and Xu, D. (2001) TH2 cytokines regulate gene expression and proinflammatory responses in xenografts. Transplantation Proceedings, 33, pp. 776-777.

Campbell, C., Goodridge, H., Harnett, M. , Harnett, W., Liew, F. and Wilson, E. (2001) Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae. Journal of Immunology, 167, pp. 940-945.

Campbell, C., Kang, D., Leung, B., Liew, F., Schulz, K., Sogaard, M., Sweet, M., Trajkovic, V. and Xu, D. (2001) A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of toll-like receptor 4 expression. Journal of Immunology, 166, pp. 6633-6639.

Carter, R., Chan, W., Klemenz, R., Liew, F., Sweet, M. and Xu, D. (2001) Regulation of ST2L expression on T helper (Th) type 2 cells. European Journal of Immunology, 31, pp. 2979-2985.

Chalmers, G., Komai-Koma, M., Liew, F., Mckay, A., McSharry, C., Thomson, L. and Thomson, N. (2001) Immuno-regulatory cytokines in asthma: IL-15 and IL-13 in induced sputum. Clinical and Experimental Allergy, 31, pp. 1441-1448.

Esfandiari, E., McInnes, I. , Lindop, G., Huang, F., Field, M., Komai-Koma, M., Wei, X. and Liew, F. (2001) A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. Journal of Immunology, 167, pp. 5338-5347. (doi: 10.4049/jimmunol.167.9.5338) (PMID:11673550)

Gao, B., Gracie, J., Guan, H., Leung, B., Liew, F., McInnes, I. , Niedbala, W., Orchardson, M., Paterson, G. and Wei, X. (2001) The sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. Journal of Immunology, 167, pp. 277-282.

Jiang, H., Wei, X., Niedbala, W., Lumsden, L., Liew, F. and Forrester, J. (2001) IL-18 not required for IRBP peptide-induced EAU: Studies in gene-deficient mice. Investigative Ophthalmology and Visual Science, 42, pp. 177-182.

Leung, B. P., Culshaw, S. , Gracie, J. A., Hunter, D., Canetti, C. A., Campbell, C., Cunha, F., Liew, F. Y. and McInnes, I. B. (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167, pp. 2879-2886. (doi: 10.4049/jimmunol.167.5.2879) (PMID:11509635)

McInnes, I. B. , Gracie, J. A. and Liew, F. Y. (2001) Interleukin-18: A novel cytokine in inflammatory rheumatic disease. Arthritis and Rheumatism, 44(7), pp. 1481-1483. (doi: 10.1002/1529-0131(200107)44:7<1481::AID-ART268>3.0.CO;2-1) (PMID:11465697)

Wei, X.-q., Leung, B. P., Arthur, H. M. L., Liew, F. Y. and McInnes, I. B. (2001) Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. Journal of Immunology, 166, pp. 517-521. (doi: 10.4049/jimmunol.166.1.517) (PMID:11123331)

Bolton, E., Bradley, J., Liew, F., Ruchatz, H., Smith, X. and Wei, X. (2000) Selective blockade of IL-15 by soluble IL-15 receptor alpha-chain enhances cardiac allograft survival. Journal of Immunology, 165(6), pp. 3444-3450.

Leung, B., Liew, F. and McInnes, I. (2000) Cell-cell interactions in synovitis - Interactions between T lymphocytes and synovial cells. Arthritis Research, 2(5), pp. 374-378.

Smith, K., Pottage, L., Thomas, E., Leishman, A., Doig, T., Xu, D., Liew, F. and Garside, P. (2000) Th1 and Th2CD4(+) T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo. Journal of Immunology, 165(6), pp. 3136-3144.

Xu, D., Trajkovic, V., Hunter, D., Leung, B. P., Schulz, K., Gracie, J. A., McInnes, I. B. and Liew, F. Y. (2000) IL-18 induces the differentiation of Th1 or Th2 cells depending upon cytokine milieu and genetic background. European Journal of Immunology, 30(11), pp. 3147-3156. (doi: 10.1002/1521-4141(200011)30:11<3147::AID-IMMU3147>3.0.CO;2-J) (PMID:11093129)

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Kropf, P., Schopf, L. R., Chung, C. L., Xu, D., Liew, F. Y., Sypek, J. P. and Müller, I. (1999) Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection. European Journal of Immunology, 29(11), pp. 3621-3628. (doi: 10.1002/(SICI)1521-4141(199911)29:11<3621::AID-IMMU3621>3.0.CO;2-Z) (PMID:10556817)

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Piedrafita, D., Xu, D., Hunter, D., Harrison, R. A. and Liew, F. Y. (1999) Protective immune responses induced by vaccination with an expression genomic library of leishmania major. Journal of Immunology, 163(3), pp. 1467-1472. (PMID:10415048)

Huang, F.-P., Niedbala, W., Wei, X.-Q., Xu, D., Feng, G.-j., Robinson, J. H., Lam, C. and Liew, F. Y. (1998) Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. European Journal of Immunology, 28(12), pp. 4062-4070. (doi: 10.1002/(SICI)1521-4141(199812)28:12<4062::AID-IMMU4062>3.0.CO;2-K) (PMID:9862342)

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Brewer, J. M. , Tetley, L., Richmond, J., Liew, F. Y. and Alexander, J. (1998) Lipid vesicle size determines the Th1 or Th2 response to entrapped antigen. Journal of Immunology, 161(8), pp. 4000-4007. (PMID:9780169)

Huang, F.-P., Xu, D., Esfandiari, E.-O., Sands, W., Wei, X.-q. and Liew, F. Y. (1998) Cutting edge: Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated interleukin-12 synthesis, strong Th1 responses and enhanced nitric oxide production. Journal of Immunology, 160(9), pp. 4143-4147. (PMID:9574511)

Xu, D., McSorley, S. J., Tetley, L., Chatfield, S., Dougan, G., Chan, W. L., Satoskar, A., David, J. R. and Liew, F. Y. (1998) Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium. Journal of Immunology, 160(3), pp. 1285-1289. (PMID:9570545)

McInnes, I. B. , Leung, B. P., Sturrock, R. D., Field, M. and Liew, F. Y. (1997) Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis. Nature Medicine, 3(2), pp. 189-195. (doi: 10.1038/nm0297-189) (PMID:9018238)

Mcsorley, S. J., Xu, D. and Liew, F.Y. (1997) Vaccine efficacy of Salmonella strains expressing glycoprotein 63 with different promoters. Infection and Immunity, 65(1), pp. 171-178. (PMID:8975908)

McInnes, I. B. , Leung, B. P., Field, M., Wei, X. Q., Huang, F.-P., Sturrock, R. D., Kinninmonth, A., Weidner, J., Mumford, R. and Liew, F. Y. (1996) Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. Journal of Experimental Medicine, 184(4), pp. 1519-1524. (doi: 10.1084/jem.184.4.1519) (PMID:8879223) (PMCID:PMC2192822)

Huang, F.P., Feng, G.J., Lindop, G., Stott, D.I. and Liew, F.Y. (1996) The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. Journal of Experimental Medicine, 183(4), pp. 1447-1459.

McInnes, I. B. , Al-Mughales, J., Field, M., Leung, B. P., Huang, F.-p., Dixon, R., Sturrock, R. D., Wilkinson, P. C. and Liew, F. Y. (1996) The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis. Nature Medicine, 2(2), pp. 175-182. (doi: 10.1038/nm0296-175) (PMID:8574962)

Wei, X.-q., Charles, I. G., Smith, A., Ure, J., Feng, G.-j., Huang, F.-p., Xu, D., Mullers, W., Moncada, S. and Liew, F. Y. (1995) Altered immune responses in mice lacking inducible nitric oxide synthase. Nature, 375(6530), pp. 408-411. (doi: 10.1038/375408a0) (PMID:7539113)

Xu, D. and Liew, F.Y. (1995) Protection against leishmaniasis by injection of DNA encoding a major surface glycoprotein, gp63, of L. major. Immunology, 84(2), pp. 173-176. (PMID:7750991)

Ianaro, A., Xu, D., O'Donnell, C.A. , Di Rosa, M. and Liew, F.Y. (1995) Expression of TGF-beta in attenuated Salmonella typhimurium: oral administration leads to the reduction of inflammation, IL-2 and IFN-gamma, but enhancement of IL-10, in carrageenin-induced oedema in mice. Immunology, 84(1), pp. 8-15. (PMID:7890306)

Xu, D., McSorley, S.J., Chatfield, S.N., Dougan, G. and Liew, F.Y. (1995) Protection against Leishmania major infection in genetically susceptible BALB/c mice by gp63 delivered orally in attenuated Salmonella typhimurium (AroA- AroD-). Immunology, 85(1), pp. 1-7. (PMID:7635511)

Xu, D. and Liew, F.Y. (1994) Genetic vaccination against leishmaniasis. Vaccine, 12(16), pp. 1534-1536. (doi: 10.1016/0264-410X(94)90079-5) (PMID:7879420)

Taylor-Robinson, A. W., Liew, F. Y., Severn, A., Xu, D., McSorley, S. J., Garside, P. , Padron, J. and Phillips, R. S. (1994) Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells. European Journal of Immunology, 24(4), pp. 980-984. (doi: 10.1002/eji.1830240430) (PMID:8149966)

Sands, W. A., Bulut, V., Severn, A., Xu, D. and Liew, F. Y. (1994) Inhibition of nitric oxide synthesis by interleukin-4 may involve inhibiting the activation of protein kinase C epsilon. European Journal of Immunology, 24(10), pp. 2345-2350. (doi: 10.1002/eji.1830241013) (PMID:7523136)

Severn, A., Xu, D., Doyle, J., Leal, L. M. C., O'Donnell, C. A. , Brett, S. J., Moss, D. W. and Liew, F. Y. (1993) Pre-exposure of murine macrophages to lipopolysaccharide inhibits the induction of nitric oxide synthase and reduces leishmanicidal activity. European Journal of Immunology, 23(7), pp. 1711-1714. (doi: 10.1002/eji.1830230747) (PMID:7686861)

Cunha, F. Q., Assreuy, J., Xu, D., Charles, I., Liew, F. Y. and Moncada, S. (1993) Repeated induction of nitric oxide synthase and leishmanicidal activity in murine macrophages. European Journal of Immunology, 23(6), pp. 1385-1388. (doi: 10.1002/eji.1830230631) (PMID:7684689)

Conference Proceedings

Kurowska-Stolarska, M. , Ballantine, L., Stolarski, B., Hunter, J., Hueber, A., Gracie, J.A., Liew, F. Y. and McInnes, I. B. (2010) miR-155 and miR-34a regulate proinflammatory cytokine production by human monocytes. In: European Workshop for Rheumatology Research, Bamberg, Germany, 4-7 Mar 2010, A30-A30. (doi: 10.1136/ard.2010.129619g)

Kurowska-Stolarska, M. S. , Kewin, P., Stolarski, B., Fraser, A., Xu, D., McInnes, I. and Liew, F. Y. (2008) A role of IL-33 in bone turnover. In: 72nd Annual Scientific Meeting of the American College of Rheumatology and the 43rd Annual Scientific Meeting of the Association of Rheumatology Health Professionals, San Francisco CA, USA, 24-29 Oct 2008, S895.

Kewin, P., Kurowska-Stolarska, M. , Murphy, G., Pitman, N., ChooKang, B., Patel, M., Xu, D., Liew, F.Y. and Thomson, N. (2008) IL-33 is sufficient to induce eosinophilic airway inflammation, and exacerbates established inflammation, through increased local Th2 cytokine and chemokine production. In: Scottish Thoracic Society Meeting, Stirling, UK, 26 Oct 2007, p. 50. (doi: 10.1258/rsmsmj.53.2.48)

Kewin, P., Kurowska-Stolarska, M. , Murphy, G., Pitman, N., ChooKang, B., Patel, M., Xu, D., Liew, F.Y. and Thomson, N. (2007) IL-33 is sufficient to induce eosinophilic airway inflammation, and exacerbates established inflammation, through increased ST2 dependent local Th2 cytokine and chemokine production. In: Winter Meeting of the British-Thoracic-Society, London, UK, 05-07 Dec 2007, A1.

This list was generated on Thu Dec 9 13:10:16 2021 GMT.