Dr Angela Ianniciello
- Honorary Research Fellow (School of Cancer Sciences)
Publications
2024
Zarou, M. M. et al. (2024) Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing. Nature Communications, 15, 1931. (doi: 10.1038/s41467-024-46114-0) (PMID:38431691) (PMCID:PMC10908830)
Dawson, A. et al. (2024) Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature Communications, 15, 1090. (doi: 10.1038/s41467-024-45471-0) (PMID:38316788) (PMCID:PMC10844594)
2023
Rattigan, K. M. et al. (2023) Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells. EMBO Reports, 24, e56279. (doi: 10.15252/embr.202256279) (PMID:37489735) (PMCID:PMC10561355)
Rattigan, K. M. et al. (2023) Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells. Nature Communications, 14, 4634. (doi: 10.1038/s41467-023-40222-z) (PMID:37591854) (PMCID:PMC10435520)
2022
Ianniciello, Angela and Helgason, G. Vignir ORCID: https://orcid.org/0000-0003-1616-132X
(2022)
Targeting ULK1 in cancer stem cells: insight from chronic myeloid leukemia.
Autophagy, 18(7),
pp. 1734-1736.
(doi: 10.1080/15548627.2022.2041152)
(PMID:35227175)
(PMCID:PMC9298457)
2021
Ianniciello, A. et al. (2021) ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science Translational Medicine, 13(613), eabd5016. (doi: 10.1126/scitranslmed.abd5016) (PMID:34586834)
Ianniciello, Angela and Helgason, G. Vignir ORCID: https://orcid.org/0000-0003-1616-132X
(2021)
Autophagy in hematopoiesis and leukemogenesis.
In: Rothermel, Beverly A. and Diwan, Abhinav (eds.)
Autophagy in Health and Disease. Second Edition.
Academic Press: London, pp. 125-141.
ISBN 9780128220030
(doi: 10.1016/B978-0-12-822003-0.00021-8)
2019
Baquero, P. et al. (2019) Targeting quiescent leukemic stem cells using second generation autophagy inhibitors. Leukemia, 33(4), pp. 981-994. (doi: 10.1038/s41375-018-0252-4) (PMID:30185934) (PMCID:PMC6292500)
2018
Ianniciello, Angela, Rattigan, Kevin M. and Helgason, G. Vignir ORCID: https://orcid.org/0000-0003-1616-132X
(2018)
The ins and outs of autophagy and metabolism in hematopoietic and leukemic stem cells: food for thought.
Frontiers in Cell and Developmental Biology, 6,
120.
(doi: 10.3389/fcell.2018.00120)
(PMID:30320108)
(PMCID:PMC6169402)
Articles
Zarou, M. M. et al. (2024) Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing. Nature Communications, 15, 1931. (doi: 10.1038/s41467-024-46114-0) (PMID:38431691) (PMCID:PMC10908830)
Dawson, A. et al. (2024) Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature Communications, 15, 1090. (doi: 10.1038/s41467-024-45471-0) (PMID:38316788) (PMCID:PMC10844594)
Rattigan, K. M. et al. (2023) Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells. EMBO Reports, 24, e56279. (doi: 10.15252/embr.202256279) (PMID:37489735) (PMCID:PMC10561355)
Rattigan, K. M. et al. (2023) Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells. Nature Communications, 14, 4634. (doi: 10.1038/s41467-023-40222-z) (PMID:37591854) (PMCID:PMC10435520)
Ianniciello, Angela and Helgason, G. Vignir ORCID: https://orcid.org/0000-0003-1616-132X
(2022)
Targeting ULK1 in cancer stem cells: insight from chronic myeloid leukemia.
Autophagy, 18(7),
pp. 1734-1736.
(doi: 10.1080/15548627.2022.2041152)
(PMID:35227175)
(PMCID:PMC9298457)
Ianniciello, A. et al. (2021) ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science Translational Medicine, 13(613), eabd5016. (doi: 10.1126/scitranslmed.abd5016) (PMID:34586834)
Baquero, P. et al. (2019) Targeting quiescent leukemic stem cells using second generation autophagy inhibitors. Leukemia, 33(4), pp. 981-994. (doi: 10.1038/s41375-018-0252-4) (PMID:30185934) (PMCID:PMC6292500)
Ianniciello, Angela, Rattigan, Kevin M. and Helgason, G. Vignir ORCID: https://orcid.org/0000-0003-1616-132X
(2018)
The ins and outs of autophagy and metabolism in hematopoietic and leukemic stem cells: food for thought.
Frontiers in Cell and Developmental Biology, 6,
120.
(doi: 10.3389/fcell.2018.00120)
(PMID:30320108)
(PMCID:PMC6169402)
Book Sections
Ianniciello, Angela and Helgason, G. Vignir ORCID: https://orcid.org/0000-0003-1616-132X
(2021)
Autophagy in hematopoiesis and leukemogenesis.
In: Rothermel, Beverly A. and Diwan, Abhinav (eds.)
Autophagy in Health and Disease. Second Edition.
Academic Press: London, pp. 125-141.
ISBN 9780128220030
(doi: 10.1016/B978-0-12-822003-0.00021-8)