2026

Himonas, E. et al. (2026) A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia. Blood, (doi: 10.1182/blood.2024027853) (PMID:41734389) (Early Online Publication)

2025

Gajic, N. et al. (2025) Selenocysteine Dependency Renders Central Nervous System Leukaemia Therapeutically Sensitive to Ferroptosi. 67th American Society of Hematology Annual Meeting, Orlando, USA, 06-09 Dec 2025. (doi: 10.1182/blood-2025-1526)

Gajic, N. et al. (2025) NADPH Controls a Cell State Vulnerability Towards Ferroptosis in Acute Lymphoblastic Leukaemia. 67th American Society of Hematology Annual Meeting, Orlando, USA, 06-09 Dec 2025. p. 144. (doi: 10.1182/blood-2025-144)

Boscenco, S. et al. (2025) Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer. Nature Genetics, 57(11), pp. 2705-2714. (doi: 10.1038/s41588-025-02374-0) (PMID:41184543) (PMCID:PMC12597822)

Whyte, D. et al. (2025) Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes. EMBO Reports, 26(17), pp. 4248-4282. (doi: 10.1038/s44319-025-00520-7) (PMID:40702342) (PMCID:PMC12420820)

Gounis, M. et al. (2025) Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments. Journal of Cell Biology, 224(8), e202405061. (doi: 10.1083/jcb.202405061) (PMID:40488669) (PMCID:PMC12147664)

2024

Kiourtis, C. et al. (2024) Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ. Nature Cell Biology, 26(12), pp. 2075-2083. (doi: 10.1038/s41556-024-01543-3) (PMID:39537753) (PMCID:PMC11628396)

Jans, M. et al. (2024) Colibactin-driven colon cancer requires adhesin-mediated epithelial binding. Nature, 635(8038), pp. 472-480. (doi: 10.1038/s41586-024-08135-z) (PMID:39506107)

Khalaf, A. et al. (2024) Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia. Science Translational Medicine, 16(751), eadi5336. (doi: 10.1126/scitranslmed.adi5336) (PMID:38865484)

Zarou, M. M. et al. (2024) Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing. Nature Communications, 15, 1931. (doi: 10.1038/s41467-024-46114-0) (PMID:38431691) (PMCID:PMC10908830)

Articles

Himonas, E. et al. (2026) A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia. Blood, (doi: 10.1182/blood.2024027853) (PMID:41734389) (Early Online Publication)

Boscenco, S. et al. (2025) Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer. Nature Genetics, 57(11), pp. 2705-2714. (doi: 10.1038/s41588-025-02374-0) (PMID:41184543) (PMCID:PMC12597822)

Whyte, D. et al. (2025) Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes. EMBO Reports, 26(17), pp. 4248-4282. (doi: 10.1038/s44319-025-00520-7) (PMID:40702342) (PMCID:PMC12420820)

Gounis, M. et al. (2025) Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments. Journal of Cell Biology, 224(8), e202405061. (doi: 10.1083/jcb.202405061) (PMID:40488669) (PMCID:PMC12147664)

Kiourtis, C. et al. (2024) Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ. Nature Cell Biology, 26(12), pp. 2075-2083. (doi: 10.1038/s41556-024-01543-3) (PMID:39537753) (PMCID:PMC11628396)

Jans, M. et al. (2024) Colibactin-driven colon cancer requires adhesin-mediated epithelial binding. Nature, 635(8038), pp. 472-480. (doi: 10.1038/s41586-024-08135-z) (PMID:39506107)

Khalaf, A. et al. (2024) Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia. Science Translational Medicine, 16(751), eadi5336. (doi: 10.1126/scitranslmed.adi5336) (PMID:38865484)

Zarou, M. M. et al. (2024) Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing. Nature Communications, 15, 1931. (doi: 10.1038/s41467-024-46114-0) (PMID:38431691) (PMCID:PMC10908830)

Conference or Workshop Item

Gajic, N. et al. (2025) Selenocysteine Dependency Renders Central Nervous System Leukaemia Therapeutically Sensitive to Ferroptosi. 67th American Society of Hematology Annual Meeting, Orlando, USA, 06-09 Dec 2025. (doi: 10.1182/blood-2025-1526)

Gajic, N. et al. (2025) NADPH Controls a Cell State Vulnerability Towards Ferroptosis in Acute Lymphoblastic Leukaemia. 67th American Society of Hematology Annual Meeting, Orlando, USA, 06-09 Dec 2025. p. 144. (doi: 10.1182/blood-2025-144)