Dr Christopher Delaney
- Lecturer in Biomedical Sciences (Dental School)
Publications
2024
Short, B., Delaney, C., Johnston, W., Litherland, G. J., Lockhart, J. C., Williams, C., MacKay, W. G. and Ramage, G. (2024) Informed development of a multi-species biofilm in chronic obstructive pulmonary disease. APMIS: Journal of Pathology, Microbiology and Immunology, (doi: 10.1111/apm.13386) (PMID:38379455) (Early Online Publication)
2023
Delaney, C., Short, B., Rajendran, R., Kean, R., Burgess, K., Williams, C., Munro, C. A. and Ramage, G. (2023) An integrated transcriptomic and metabolomic approach to investigate the heterogeneous Candida albicans biofilm phenotype. Biofilm, 5, 100112. (doi: 10.1016/j.bioflm.2023.100112) (PMID:36969800) (PMCID:PMC10034394)
Johnston, W., Ware, A., Kuiters, W. F., Delaney, C., Brown, J. L. , Hagen, S., Corcoran, D., Cummings, M., Ramage, G. and Kean, R. (2023) In vitro bacterial vaginosis biofilm community manipulation using endolysin therapy. Biofilm, 5, 100101. (doi: 10.1016/j.bioflm.2022.100101) (PMID:36655001) (PMCID:PMC9841237)
Delaney, C., Alapati, S., Alshehri, M., Kubalova, D., Veena, C. L. R., Abusrewil, S., Short, B., Bradshaw, D. and Brown, J. L. (2023) Investigating the role of Candida albicans as a universal substrate for oral bacteria using a transcriptomic approach: implications for interkingdom biofilm control? APMIS: Journal of Pathology, Microbiology and Immunology, 131(11), pp. 601-612. (doi: 10.1111/apm.13327) (PMID:37170476)
Alapati, S., Fortuna, G., Ramage, G. and Delaney, C. (2023) Evaluation of metabolomics as diagnostic targets in oral squamous cell carcinoma: a systematic review. Metabolites, 13, 890. (doi: 10.3390/metabo13080890) (PMID:37766254) (PMCID:PMC10456490)
Delaney, C., Veena, C. L. R., Butcher, M. C., Mclean, W. , Shaban, S. M. A., Nile, C. J. and Ramage, G. (2023) Limitations of using 16S rRNA microbiome sequencing to predict oral squamous cell carcinoma. APMIS: Journal of Pathology, Microbiology and Immunology, 131(6), pp. 262-276. (doi: 10.1111/apm.13315) (PMID:37002549)
2022
Alshanta, O. A., Albashaireh, K., McKloud, E., Delaney, C., Kean, R., McLean, W. and Ramage, G. (2022) Candida albicans and Enterococcus faecalis biofilm frenemies: when the relationship sours. Biofilm, 4, 100072. (doi: 10.1016/j.bioflm.2022.100072) (PMID:35313556) (PMCID:PMC8933684)
Butcher, M. C., Short, B., Ramalingam Veena, C. L., Bradshaw, D., Pratten, J. R., McLean, W. , Shaban, S. M. A., Ramage, G. and Delaney, C. (2022) Meta-analysis of caries microbiome studies can improve upon disease prediction outcomes. APMIS: Journal of Pathology, Microbiology and Immunology, 130(12), pp. 763-777. (doi: 10.1111/apm.13272) (PMID:36050830) (PMCID:PMC9825849)
Gülmez, D., Brown, J. L. , Butcher, M. C., Delaney, C., Kean, R., Ramage, G. and Short, B. (2022) Investigating dual-species Candida auris and staphylococcal biofilm antiseptic challenge. Antibiotics, 11(7), 931. (doi: 10.3390/antibiotics11070931) (PMID:35884184) (PMCID:PMC9312070)
Helmstetter, N. et al. (2022) Population genetics and microevolution of clinical Candida glabrata reveals recombinant sequence types and hyper-variation within mitochondrial genomes, virulence genes and drug-targets. Genetics, 221(1), iyac031. (doi: 10.1093/genetics/iyac031) (PMID:35199143)
2021
Short, B., Delaney, C., McKloud, E., Brown, J. L. , Kean, R., Litherland, G. J., Williams, C., Martin, S. L., MacKay, W. G. and Ramage, G. (2021) Investigating the transcriptome of Candida albicans in a dual-species Staphylococcus aureus biofilm mode. Frontiers in Cellular and Infection Microbiology, 11, 791523. (doi: 10.3389/fcimb.2021.791523)
Abusrewil, S., Brown, J. L. , Delaney, C., Butcher, M. C., Tiba, M., Scott, J. A. , Ramage, G. and McLean, W. (2021) Chitosan enhances the anti-biofilm activity of biodentine against an interkingdom biofilm model. Antibiotics, 10(11), 1317. (doi: 10.3390/antibiotics10111317)
McKloud, E. et al. (2021) Recurrent vulvovaginal candidiasis: a dynamic interkingdom biofilm disease of Candida and Lactobacillus. mSystems, 6(4), e00622-21. (doi: 10.1128/mSystems.00622-21) (PMID:34374560) (PMCID:PMC8407231)
Johnston, W., Rosier, B.T., Artacho, A., Paterson, M., Piela, K., Delaney, C., Brown, J.L. , Ramage, G. , Mira, A. and Culshaw, S. (2021) Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients. Scientific Reports, 11, 9796. (doi: 10.1038/s41598-021-89002-z) (PMID:33963212) (PMCID:PMC8105330)
2020
Abusrewil, S., Brown, J. L. , Delaney, C. D., Butcher, M. C., Kean, R., Gamal, D., Scott, J. A. , McLean, W. and Ramage, G. (2020) Filling the void: an optimized polymicrobial interkingdom biofilm model for assessing novel antimicrobial agents in endodontic infection. Microorganisms, 8(12), 1988. (doi: 10.3390/microorganisms8121988) (PMID:33327403) (PMCID:PMC7764896)
Salomão Arias, L., Butcher, M. C., Short, B., McKloud, E., Delaney, C., Kean, R., Monteiro, D. R., Williams, C., Ramage, G. and Brown, J. L. (2020) Chitosan ameliorates Candida auris virulence in a Galleria mellonella infection model. Antimicrobial Agents and Chemotherapy, 64(8), e00476-20. (doi: 10.1128/AAC.00476-20) (PMID:32482674) (PMCID:PMC7526850)
Brown, J. L. , Delaney, C., Short, B., Butcher, M. C., McKloud, E., Williams, C., Kean, R. and Ramage, G. (2020) Candida auris phenotypic heterogeneity determines pathogenicity in vitro. mSphere, 5(3), e00371-20. (doi: 10.1128/mSphere.00371-20) (PMID:32581078) (PMCID:PMC7316489)
Arias, L. S., Brown, J. L. , Butcher, M. C., Delaney, C., Monteiro, D. R. and Ramage, G. (2020) A nanocarrier system that potentiates the effect of miconazole within different interkingdom biofilms. Journal of Oral Microbiology, 12(1), 1771071. (doi: 10.1080/20002297.2020.1771071) (PMID:32922677) (PMCID:PMC7448886)
Seneviratne, C. J., Suriyanarayanan, T., Widyarman, A. S., Lee, L. S., Lau, M., Ching, J., Delaney, C. and Ramage, G. (2020) Multi-omics tools for studying microbial biofilms: current perspectives and future directions. Critical Reviews in Microbiology, 46(6), pp. 759-778. (doi: 10.1080/1040841X.2020.1828817) (PMID:33030973)
2019
Delaney, C. et al. (2019) Interkingdom interactions on the denture surface: implications for oral hygiene. Biofilm, 1, 100002. (doi: 10.1016/j.bioflm.2019.100002) (PMID:32201858) (PMCID:PMC7067236)
Brown, J. L. , Johnston, W., Delaney, C., Short, B., Butcher, M. C., Young, T., Butcher, J., Riggio, M. , Culshaw, S. and Ramage, G. (2019) Polymicrobial oral biofilm models: simplifying the complex. Journal of Medical Microbiology, 68(11), pp. 1573-1584. (doi: 10.1099/jmm.0.001063) (PMID:31524581)
Short, B., Brown, J. , Delaney, C., Sherry, L. , Williams, C., Ramage, G. and Kean, R. (2019) Candida auris exhibits resilient biofilm characteristics in vitro: implications for environmental persistence. Journal of Hospital Infection, 103(1), pp. 92-96. 31226270. (doi: 10.1016/j.jhin.2019.06.006)
Nile, C. et al. (2019) Repurposing Pilocarpine Hydrochloride for the treatment of Candida albicans infections. mSphere, 4(1), e00689-18. (doi: 10.1128/mSphere.00689-18) (PMID:30674648) (PMCID:PMC6344604)
Brown, J. L. , Johnston, W., Delaney, C., Rajendran, R., Butcher, J., Khan, S., Bradshaw, D., Ramage, G. and Culshaw, S. (2019) Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells. Scientific Reports, 9, 15779. (doi: 10.1038/s41598-019-52115-7) (PMID:31673005) (PMCID:PMC6823452)
2018
Kean, R., McKloud, E., Townsend, E. M., Sherry, L. , Delaney, C., Jones, B. L., Williams, C. and Ramage, G. (2018) The comparative efficacy of antiseptics against Candida auris biofilms. International Journal of Antimicrobial Agents, 52(5), pp. 673-677. (doi: 10.1016/j.ijantimicag.2018.05.007) (PMID:29775686)
Delaney, C., Kean, R., Short, B., Tumelty, M., McLean, W. , Nile, C. and Ramage, G. (2018) Fungi at the scene of the crime: innocent bystanders or accomplices in oral infections? Current Clinical Microbiology Reports, 5(3), pp. 190-200. (doi: 10.1007/s40588-018-0100-3)
Kean, R., Delaney, C., Sherry, L. , Borman, A., Johnson, E. M., Richardson, M. D., Rautemaa-Richardson, R., Williams, C. and Ramage, G. (2018) Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance. mSphere, 3, e00334-18. (doi: 10.1128/mSphere.00334-18) (PMID:29997121) (PMCID:PMC6041501)
Kean, R., Delaney, C., Rajendran, R., Sherry, L. , Metcalfe, R., Thomas, R., McLean, W. , Williams, C. and Ramage, G. (2018) Gaining insights from Candida biofilm heterogeneity: one size does not fit all. Journal of Fungi, 4(1), 12. (doi: 10.3390/jof4010012) (PMID:29371505) (PMCID:PMC5872315)
Sztukowska, M. N., Dutton, L. C., Delaney, C., Ramsdale, M., Ramage, G. , Jenkinson, H. F., Nobbs, A. H. and Lamont, R. J. (2018) Community development between Porphyromonas gingivalis and Candida albicans mediated by InlJ and Als3. mBio, 9(2), e00202-18. (doi: 10.1128/mBio.00202-18) (PMID:29691333) (PMCID:PMC5915736)
Articles
Short, B., Delaney, C., Johnston, W., Litherland, G. J., Lockhart, J. C., Williams, C., MacKay, W. G. and Ramage, G. (2024) Informed development of a multi-species biofilm in chronic obstructive pulmonary disease. APMIS: Journal of Pathology, Microbiology and Immunology, (doi: 10.1111/apm.13386) (PMID:38379455) (Early Online Publication)
Delaney, C., Short, B., Rajendran, R., Kean, R., Burgess, K., Williams, C., Munro, C. A. and Ramage, G. (2023) An integrated transcriptomic and metabolomic approach to investigate the heterogeneous Candida albicans biofilm phenotype. Biofilm, 5, 100112. (doi: 10.1016/j.bioflm.2023.100112) (PMID:36969800) (PMCID:PMC10034394)
Johnston, W., Ware, A., Kuiters, W. F., Delaney, C., Brown, J. L. , Hagen, S., Corcoran, D., Cummings, M., Ramage, G. and Kean, R. (2023) In vitro bacterial vaginosis biofilm community manipulation using endolysin therapy. Biofilm, 5, 100101. (doi: 10.1016/j.bioflm.2022.100101) (PMID:36655001) (PMCID:PMC9841237)
Delaney, C., Alapati, S., Alshehri, M., Kubalova, D., Veena, C. L. R., Abusrewil, S., Short, B., Bradshaw, D. and Brown, J. L. (2023) Investigating the role of Candida albicans as a universal substrate for oral bacteria using a transcriptomic approach: implications for interkingdom biofilm control? APMIS: Journal of Pathology, Microbiology and Immunology, 131(11), pp. 601-612. (doi: 10.1111/apm.13327) (PMID:37170476)
Alapati, S., Fortuna, G., Ramage, G. and Delaney, C. (2023) Evaluation of metabolomics as diagnostic targets in oral squamous cell carcinoma: a systematic review. Metabolites, 13, 890. (doi: 10.3390/metabo13080890) (PMID:37766254) (PMCID:PMC10456490)
Delaney, C., Veena, C. L. R., Butcher, M. C., Mclean, W. , Shaban, S. M. A., Nile, C. J. and Ramage, G. (2023) Limitations of using 16S rRNA microbiome sequencing to predict oral squamous cell carcinoma. APMIS: Journal of Pathology, Microbiology and Immunology, 131(6), pp. 262-276. (doi: 10.1111/apm.13315) (PMID:37002549)
Alshanta, O. A., Albashaireh, K., McKloud, E., Delaney, C., Kean, R., McLean, W. and Ramage, G. (2022) Candida albicans and Enterococcus faecalis biofilm frenemies: when the relationship sours. Biofilm, 4, 100072. (doi: 10.1016/j.bioflm.2022.100072) (PMID:35313556) (PMCID:PMC8933684)
Butcher, M. C., Short, B., Ramalingam Veena, C. L., Bradshaw, D., Pratten, J. R., McLean, W. , Shaban, S. M. A., Ramage, G. and Delaney, C. (2022) Meta-analysis of caries microbiome studies can improve upon disease prediction outcomes. APMIS: Journal of Pathology, Microbiology and Immunology, 130(12), pp. 763-777. (doi: 10.1111/apm.13272) (PMID:36050830) (PMCID:PMC9825849)
Gülmez, D., Brown, J. L. , Butcher, M. C., Delaney, C., Kean, R., Ramage, G. and Short, B. (2022) Investigating dual-species Candida auris and staphylococcal biofilm antiseptic challenge. Antibiotics, 11(7), 931. (doi: 10.3390/antibiotics11070931) (PMID:35884184) (PMCID:PMC9312070)
Helmstetter, N. et al. (2022) Population genetics and microevolution of clinical Candida glabrata reveals recombinant sequence types and hyper-variation within mitochondrial genomes, virulence genes and drug-targets. Genetics, 221(1), iyac031. (doi: 10.1093/genetics/iyac031) (PMID:35199143)
Short, B., Delaney, C., McKloud, E., Brown, J. L. , Kean, R., Litherland, G. J., Williams, C., Martin, S. L., MacKay, W. G. and Ramage, G. (2021) Investigating the transcriptome of Candida albicans in a dual-species Staphylococcus aureus biofilm mode. Frontiers in Cellular and Infection Microbiology, 11, 791523. (doi: 10.3389/fcimb.2021.791523)
Abusrewil, S., Brown, J. L. , Delaney, C., Butcher, M. C., Tiba, M., Scott, J. A. , Ramage, G. and McLean, W. (2021) Chitosan enhances the anti-biofilm activity of biodentine against an interkingdom biofilm model. Antibiotics, 10(11), 1317. (doi: 10.3390/antibiotics10111317)
McKloud, E. et al. (2021) Recurrent vulvovaginal candidiasis: a dynamic interkingdom biofilm disease of Candida and Lactobacillus. mSystems, 6(4), e00622-21. (doi: 10.1128/mSystems.00622-21) (PMID:34374560) (PMCID:PMC8407231)
Johnston, W., Rosier, B.T., Artacho, A., Paterson, M., Piela, K., Delaney, C., Brown, J.L. , Ramage, G. , Mira, A. and Culshaw, S. (2021) Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients. Scientific Reports, 11, 9796. (doi: 10.1038/s41598-021-89002-z) (PMID:33963212) (PMCID:PMC8105330)
Abusrewil, S., Brown, J. L. , Delaney, C. D., Butcher, M. C., Kean, R., Gamal, D., Scott, J. A. , McLean, W. and Ramage, G. (2020) Filling the void: an optimized polymicrobial interkingdom biofilm model for assessing novel antimicrobial agents in endodontic infection. Microorganisms, 8(12), 1988. (doi: 10.3390/microorganisms8121988) (PMID:33327403) (PMCID:PMC7764896)
Salomão Arias, L., Butcher, M. C., Short, B., McKloud, E., Delaney, C., Kean, R., Monteiro, D. R., Williams, C., Ramage, G. and Brown, J. L. (2020) Chitosan ameliorates Candida auris virulence in a Galleria mellonella infection model. Antimicrobial Agents and Chemotherapy, 64(8), e00476-20. (doi: 10.1128/AAC.00476-20) (PMID:32482674) (PMCID:PMC7526850)
Brown, J. L. , Delaney, C., Short, B., Butcher, M. C., McKloud, E., Williams, C., Kean, R. and Ramage, G. (2020) Candida auris phenotypic heterogeneity determines pathogenicity in vitro. mSphere, 5(3), e00371-20. (doi: 10.1128/mSphere.00371-20) (PMID:32581078) (PMCID:PMC7316489)
Arias, L. S., Brown, J. L. , Butcher, M. C., Delaney, C., Monteiro, D. R. and Ramage, G. (2020) A nanocarrier system that potentiates the effect of miconazole within different interkingdom biofilms. Journal of Oral Microbiology, 12(1), 1771071. (doi: 10.1080/20002297.2020.1771071) (PMID:32922677) (PMCID:PMC7448886)
Seneviratne, C. J., Suriyanarayanan, T., Widyarman, A. S., Lee, L. S., Lau, M., Ching, J., Delaney, C. and Ramage, G. (2020) Multi-omics tools for studying microbial biofilms: current perspectives and future directions. Critical Reviews in Microbiology, 46(6), pp. 759-778. (doi: 10.1080/1040841X.2020.1828817) (PMID:33030973)
Delaney, C. et al. (2019) Interkingdom interactions on the denture surface: implications for oral hygiene. Biofilm, 1, 100002. (doi: 10.1016/j.bioflm.2019.100002) (PMID:32201858) (PMCID:PMC7067236)
Brown, J. L. , Johnston, W., Delaney, C., Short, B., Butcher, M. C., Young, T., Butcher, J., Riggio, M. , Culshaw, S. and Ramage, G. (2019) Polymicrobial oral biofilm models: simplifying the complex. Journal of Medical Microbiology, 68(11), pp. 1573-1584. (doi: 10.1099/jmm.0.001063) (PMID:31524581)
Short, B., Brown, J. , Delaney, C., Sherry, L. , Williams, C., Ramage, G. and Kean, R. (2019) Candida auris exhibits resilient biofilm characteristics in vitro: implications for environmental persistence. Journal of Hospital Infection, 103(1), pp. 92-96. 31226270. (doi: 10.1016/j.jhin.2019.06.006)
Nile, C. et al. (2019) Repurposing Pilocarpine Hydrochloride for the treatment of Candida albicans infections. mSphere, 4(1), e00689-18. (doi: 10.1128/mSphere.00689-18) (PMID:30674648) (PMCID:PMC6344604)
Brown, J. L. , Johnston, W., Delaney, C., Rajendran, R., Butcher, J., Khan, S., Bradshaw, D., Ramage, G. and Culshaw, S. (2019) Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells. Scientific Reports, 9, 15779. (doi: 10.1038/s41598-019-52115-7) (PMID:31673005) (PMCID:PMC6823452)
Kean, R., McKloud, E., Townsend, E. M., Sherry, L. , Delaney, C., Jones, B. L., Williams, C. and Ramage, G. (2018) The comparative efficacy of antiseptics against Candida auris biofilms. International Journal of Antimicrobial Agents, 52(5), pp. 673-677. (doi: 10.1016/j.ijantimicag.2018.05.007) (PMID:29775686)
Delaney, C., Kean, R., Short, B., Tumelty, M., McLean, W. , Nile, C. and Ramage, G. (2018) Fungi at the scene of the crime: innocent bystanders or accomplices in oral infections? Current Clinical Microbiology Reports, 5(3), pp. 190-200. (doi: 10.1007/s40588-018-0100-3)
Kean, R., Delaney, C., Sherry, L. , Borman, A., Johnson, E. M., Richardson, M. D., Rautemaa-Richardson, R., Williams, C. and Ramage, G. (2018) Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance. mSphere, 3, e00334-18. (doi: 10.1128/mSphere.00334-18) (PMID:29997121) (PMCID:PMC6041501)
Kean, R., Delaney, C., Rajendran, R., Sherry, L. , Metcalfe, R., Thomas, R., McLean, W. , Williams, C. and Ramage, G. (2018) Gaining insights from Candida biofilm heterogeneity: one size does not fit all. Journal of Fungi, 4(1), 12. (doi: 10.3390/jof4010012) (PMID:29371505) (PMCID:PMC5872315)
Sztukowska, M. N., Dutton, L. C., Delaney, C., Ramsdale, M., Ramage, G. , Jenkinson, H. F., Nobbs, A. H. and Lamont, R. J. (2018) Community development between Porphyromonas gingivalis and Candida albicans mediated by InlJ and Als3. mBio, 9(2), e00202-18. (doi: 10.1128/mBio.00202-18) (PMID:29691333) (PMCID:PMC5915736)