Professor E Milner-White

  • Honorary Senior Research Fellow (School of Molecular Biosciences)

email: James.Milner-White@glasgow.ac.uk

RA221 Level A2, Joseph Black Building, Glasgow G12 8QQ

Import to contacts

Publications

List by: Type | Date

Jump to: 2023 | 2021 | 2019 | 2017 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 | 2004 | 2003 | 2002 | 1983 | 1977 | 1972
Number of items: 30.

2023

Leader, David P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E. James (2023) The conserved crown bridge loop at the catalytic centre of enzymes of the haloacid dehalogenase superfamily. Current Research in Structural Biology, 6, 100105. (doi: 10.1016/j.crstbi.2023.100105) (PMID:37786806) (PMCID:PMC10541634)

2021

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2021) The β-link motif in protein architecture. Acta Crystallographica Section D: Structural Biology, 77(8), pp. 1040-1049. (doi: 10.1107/S2059798321006768)

Leader, David P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, James E. (2021) Identification and characterization of two classes of G1 β-bulge. Acta Crystallographica. Section D: Structural Biology, 77(2), (doi: 10.1107/S2059798320015533) (PMID:33559610) (PMCID:PMC7869896)

2019

Milner-White, E. James (2019) Protein three-dimensional structures at the origin of life. Interface Focus, 9(6), 20190057. (doi: 10.1098/rsfs.2019.0057) (PMID:31641431) (PMCID:PMC6802138)

2017

Hayward, Steven and Milner-White, E. James (2017) Geometrical principles of homomeric β-barrels and β-helices: application to modelling amyloid protofilaments. Proteins: Structure Function and Bioinformatics, 85(10), pp. 1866-1881. (doi: 10.1002/prot.25341) (PMID:28646497)

2014

Afzal, Avid M., Al-Shubailly, Fawzia, Leader, David P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E. James (2014) Bridging of anions by hydrogen bonds in nest motifs and its significance for Schellman loops and other larger motifs within proteins. Proteins: Structure Function and Bioinformatics, 82(11), pp. 3023-3031. (doi: 10.1002/prot.24663)

Hayward, S., Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843, Al-Shubailly, F. and Milner-White, E.J. (2014) Rings and ribbons in protein structures: characterization using helical parameters and Ramachandran plots for repeating dipeptides. Proteins: Structure Function and Bioinformatics, 82(2), pp. 230-239. (doi: 10.1002/prot.24357)

2013

Nitschke, W., McGlynn, S.E., Milner-White, E.J. and Russell, M.J. (2013) On the antiquity of metalloenzymes and their substrates in bioenergetics. Biochimica et Biophysica Acta: Bioenergetics, 1827(8-9), pp. 871-881. (doi: 10.1016/j.bbabio.2013.02.008)

2012

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2012) Structure motivator: a tool for exploring small three-dimensional elements in proteins. BMC Structural Biology, 12(1), p. 26. (doi: 10.1186/1472-6807-12-26)

Bianchi, A., Giorgi, C., Ruzza, P., Toniolo, C. and Milner-White, E.J. (2012) A synthetic hexapeptide designed to resemble a proteinaceous p-loop nest is shown to bind inorganic phosphate. Proteins: Structure Function and Bioinformatics, 80(5), pp. 1418-1424. (doi: 10.1002/prot.24038)

2011

Hayward, S. and Milner-White, E.J. (2011) Simulation of the β- to α-sheet transition results in a twisted sheet for antiparallel and an α-nanotube for parallel strands: implications for amyloid format. Proteins: Structure Function and Bioinformatics, 79(11), pp. 3193-3207. (doi: 10.1002/prot.23154)

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2011) The structure of the ends of α-helices in globular proteins: Effect of additional hydrogen bonds and implications for helix formation. Proteins: Structure Function and Bioinformatics, 79(3), pp. 1010-1019. (doi: 10.1002/prot.22942)

Milner-White, E.J. and Russell, M.J. (2011) Functional capabilities of the earliest peptides and the emergence of life. Genes, 2(4), pp. 671-688. (doi: 10.3390/genes2040671)

2010

Milner-White, E.J. and Russell, M.J. (2010) Polyphosphate-peptide synergy and the organic takeover at the emergence of life. Journal of Cosmology and Astroparticle Physics, 10, pp. 3217-3229.

Milner-White, E.J., Pietras, Z. and Luisi, B.F. (2010) An ancient anion-binding structural module in RNA and DNA helicases. Proteins: Structure Function and Bioinformatics, 78(8), pp. 1900-1908. (doi: 10.1002/prot.22704)

2009

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2009) Motivated proteins: a web application for studying small three-dimensional protein motifs. BMC Bioinformatics, 10(60), (doi: 10.1186/1471-2105-10-60)

Torrance, G.M., Leader, D.P., Gilbert, D.R. and Milner-White, E.J. (2009) A novel main chain motif in proteins bridged by cationic groups: the niche. Journal of Molecular Biology, 385(4), pp. 1076-1086. (doi: 10.1016/j.jmb.2008.11.007)

2008

Hayward, S. and Milner-White, E.J. (2008) The geometry of alpha-sheet: implications for its possible function as amyloid precursor in proteins. Proteins: Structure Function and Bioinformatics, 71(1), pp. 415-425. (doi: 10.1002/prot.21717)

Milner-White, E.J. and Russell, M. (2008) Predicting the conformations of peptides and proteins in early evolution. A review article submitted to Biology Direct. Biology Direct, 3(3), pp. 1-9. (doi: 10.1186/1745-6150-3-3)

Pietras, Z., Bavro, V.N., Furnham, N., Pellegrini-Calace, M., Milner-White, E.J. and Luisi, B.F. (2008) Structure and Mechanism of Drug Efflux Machinery in Gram Negative Bacteria. Current Drug Targets, 9(9), pp. 719-728. (doi: 10.2174/138945008785747743)

2006

Milner-White, EJ, Watson, JD, Qi, GY and Hayward, S (2006) Amyloid formation may involve alpha- to beta sheet interconversion via peptide plane flipping. Structure, 14, pp. 1369-1376. (doi: 10.1016/j.str.2006.06.016)

2005

Milner-White, E. James and Russell, Michael J. (2005) Sites for phosphates and iron-sulfur thiolates in the first membranes: 3 to 6 residue anion-binding motifs (nests). Origins of Life and Evolution of Biospheres, 35(1), pp. 19-27. (doi: 10.1007/s11084-005-4582-7)

2004

Duddy, WJ, Nissink, JWM, Allen, FH and Milner-White, EJ (2004) Mimicry by asx- and ST-turns of the four main types of beta-turn in proteins. Protein Science, 13, pp. 3051-3055. (doi: 10.1110/ps.04920804)

Milner-White, EJ, Nissink, JWM, Allen, FH and Duddy, WJ (2004) Recurring main-chain anion-binding motifs in short polypeptides: nests. Acta Crystallographica. Section D: Biological Crystallography, 60, pp. 1935-1942. (doi: 10.1107/S0907444904021390)

2003

Adams, Claire L., Macleod, Megan K.L. ORCID logoORCID: https://orcid.org/0000-0003-1843-8580, Milner-White, E. James, Aitken, Robert, Garside, Paul ORCID logoORCID: https://orcid.org/0000-0001-5944-0287 and Stott, D.I. (2003) Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation. Immunology, 108(3), pp. 274-287. (doi: 10.1046/j.1365-2567.2003.01583.x) (PMID:12603593)

2002

Watson, JD and Milner-White, EJ (2002) The conformations of polypeptide chains where the main-chain parts of successive residues are enantiomeric. Their occurrence in cation and anion-binding regions of proteins. Journal of Molecular Biology, 315, pp. 183-191. (doi: 10.1006/jmbi.2001.5228)

Watson, JD and Milner-White, EJ (2002) A novel main-chain anion-binding site in proteins: The nest. A particular combination of phi,psi values in successive residues gives rise to anion-binding sites that occur commonly and are found often at functionally important regions. Journal of Molecular Biology, 315, pp. 171-182. (doi: 10.1006/jmbi.2001.5227)

1983

Milner-White, E. James and Rycroft, David S. (1983) The αβ-methylene analogues of ADP and ATP act as substrates for creatine kinase: ΔG0 for this reaction and for the hydrolysis of the αβ-methylene analogue of ATP. European Journal of Biochemistry, 133(1), pp. 169-172. (doi: 10.1111/j.1432-1033.1983.tb07443.x) (PMID:6852021)

1977

Milner-White, E. James and Rycroft, David S. (1977) Phosphorus nuclear-magnetic-resonance studies of a transition-state analogue complex of creatine kinase. Biochemical Journal : Molecular Aspects, 167(3), pp. 827-829. (doi: 10.1042/bj1670827) (PMID:603637)

1972

Milner-White, E J. and Spain, P G (1972) Quaternary structure of helical proteins with globular subunits. Biochemical Journal, 130(1), 17P. (doi: 10.1042/bj1300017Pa) (PMCID:PMC1174362)

This list was generated on Mon Jun 16 00:58:24 2025 BST.
Jump to: Articles
Number of items: 30.

Articles

Leader, David P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E. James (2023) The conserved crown bridge loop at the catalytic centre of enzymes of the haloacid dehalogenase superfamily. Current Research in Structural Biology, 6, 100105. (doi: 10.1016/j.crstbi.2023.100105) (PMID:37786806) (PMCID:PMC10541634)

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2021) The β-link motif in protein architecture. Acta Crystallographica Section D: Structural Biology, 77(8), pp. 1040-1049. (doi: 10.1107/S2059798321006768)

Leader, David P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, James E. (2021) Identification and characterization of two classes of G1 β-bulge. Acta Crystallographica. Section D: Structural Biology, 77(2), (doi: 10.1107/S2059798320015533) (PMID:33559610) (PMCID:PMC7869896)

Milner-White, E. James (2019) Protein three-dimensional structures at the origin of life. Interface Focus, 9(6), 20190057. (doi: 10.1098/rsfs.2019.0057) (PMID:31641431) (PMCID:PMC6802138)

Hayward, Steven and Milner-White, E. James (2017) Geometrical principles of homomeric β-barrels and β-helices: application to modelling amyloid protofilaments. Proteins: Structure Function and Bioinformatics, 85(10), pp. 1866-1881. (doi: 10.1002/prot.25341) (PMID:28646497)

Afzal, Avid M., Al-Shubailly, Fawzia, Leader, David P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E. James (2014) Bridging of anions by hydrogen bonds in nest motifs and its significance for Schellman loops and other larger motifs within proteins. Proteins: Structure Function and Bioinformatics, 82(11), pp. 3023-3031. (doi: 10.1002/prot.24663)

Hayward, S., Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843, Al-Shubailly, F. and Milner-White, E.J. (2014) Rings and ribbons in protein structures: characterization using helical parameters and Ramachandran plots for repeating dipeptides. Proteins: Structure Function and Bioinformatics, 82(2), pp. 230-239. (doi: 10.1002/prot.24357)

Nitschke, W., McGlynn, S.E., Milner-White, E.J. and Russell, M.J. (2013) On the antiquity of metalloenzymes and their substrates in bioenergetics. Biochimica et Biophysica Acta: Bioenergetics, 1827(8-9), pp. 871-881. (doi: 10.1016/j.bbabio.2013.02.008)

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2012) Structure motivator: a tool for exploring small three-dimensional elements in proteins. BMC Structural Biology, 12(1), p. 26. (doi: 10.1186/1472-6807-12-26)

Bianchi, A., Giorgi, C., Ruzza, P., Toniolo, C. and Milner-White, E.J. (2012) A synthetic hexapeptide designed to resemble a proteinaceous p-loop nest is shown to bind inorganic phosphate. Proteins: Structure Function and Bioinformatics, 80(5), pp. 1418-1424. (doi: 10.1002/prot.24038)

Hayward, S. and Milner-White, E.J. (2011) Simulation of the β- to α-sheet transition results in a twisted sheet for antiparallel and an α-nanotube for parallel strands: implications for amyloid format. Proteins: Structure Function and Bioinformatics, 79(11), pp. 3193-3207. (doi: 10.1002/prot.23154)

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2011) The structure of the ends of α-helices in globular proteins: Effect of additional hydrogen bonds and implications for helix formation. Proteins: Structure Function and Bioinformatics, 79(3), pp. 1010-1019. (doi: 10.1002/prot.22942)

Milner-White, E.J. and Russell, M.J. (2011) Functional capabilities of the earliest peptides and the emergence of life. Genes, 2(4), pp. 671-688. (doi: 10.3390/genes2040671)

Milner-White, E.J. and Russell, M.J. (2010) Polyphosphate-peptide synergy and the organic takeover at the emergence of life. Journal of Cosmology and Astroparticle Physics, 10, pp. 3217-3229.

Milner-White, E.J., Pietras, Z. and Luisi, B.F. (2010) An ancient anion-binding structural module in RNA and DNA helicases. Proteins: Structure Function and Bioinformatics, 78(8), pp. 1900-1908. (doi: 10.1002/prot.22704)

Leader, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0635-1843 and Milner-White, E.J. (2009) Motivated proteins: a web application for studying small three-dimensional protein motifs. BMC Bioinformatics, 10(60), (doi: 10.1186/1471-2105-10-60)

Torrance, G.M., Leader, D.P., Gilbert, D.R. and Milner-White, E.J. (2009) A novel main chain motif in proteins bridged by cationic groups: the niche. Journal of Molecular Biology, 385(4), pp. 1076-1086. (doi: 10.1016/j.jmb.2008.11.007)

Hayward, S. and Milner-White, E.J. (2008) The geometry of alpha-sheet: implications for its possible function as amyloid precursor in proteins. Proteins: Structure Function and Bioinformatics, 71(1), pp. 415-425. (doi: 10.1002/prot.21717)

Milner-White, E.J. and Russell, M. (2008) Predicting the conformations of peptides and proteins in early evolution. A review article submitted to Biology Direct. Biology Direct, 3(3), pp. 1-9. (doi: 10.1186/1745-6150-3-3)

Pietras, Z., Bavro, V.N., Furnham, N., Pellegrini-Calace, M., Milner-White, E.J. and Luisi, B.F. (2008) Structure and Mechanism of Drug Efflux Machinery in Gram Negative Bacteria. Current Drug Targets, 9(9), pp. 719-728. (doi: 10.2174/138945008785747743)

Milner-White, EJ, Watson, JD, Qi, GY and Hayward, S (2006) Amyloid formation may involve alpha- to beta sheet interconversion via peptide plane flipping. Structure, 14, pp. 1369-1376. (doi: 10.1016/j.str.2006.06.016)

Milner-White, E. James and Russell, Michael J. (2005) Sites for phosphates and iron-sulfur thiolates in the first membranes: 3 to 6 residue anion-binding motifs (nests). Origins of Life and Evolution of Biospheres, 35(1), pp. 19-27. (doi: 10.1007/s11084-005-4582-7)

Duddy, WJ, Nissink, JWM, Allen, FH and Milner-White, EJ (2004) Mimicry by asx- and ST-turns of the four main types of beta-turn in proteins. Protein Science, 13, pp. 3051-3055. (doi: 10.1110/ps.04920804)

Milner-White, EJ, Nissink, JWM, Allen, FH and Duddy, WJ (2004) Recurring main-chain anion-binding motifs in short polypeptides: nests. Acta Crystallographica. Section D: Biological Crystallography, 60, pp. 1935-1942. (doi: 10.1107/S0907444904021390)

Adams, Claire L., Macleod, Megan K.L. ORCID logoORCID: https://orcid.org/0000-0003-1843-8580, Milner-White, E. James, Aitken, Robert, Garside, Paul ORCID logoORCID: https://orcid.org/0000-0001-5944-0287 and Stott, D.I. (2003) Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation. Immunology, 108(3), pp. 274-287. (doi: 10.1046/j.1365-2567.2003.01583.x) (PMID:12603593)

Watson, JD and Milner-White, EJ (2002) The conformations of polypeptide chains where the main-chain parts of successive residues are enantiomeric. Their occurrence in cation and anion-binding regions of proteins. Journal of Molecular Biology, 315, pp. 183-191. (doi: 10.1006/jmbi.2001.5228)

Watson, JD and Milner-White, EJ (2002) A novel main-chain anion-binding site in proteins: The nest. A particular combination of phi,psi values in successive residues gives rise to anion-binding sites that occur commonly and are found often at functionally important regions. Journal of Molecular Biology, 315, pp. 171-182. (doi: 10.1006/jmbi.2001.5227)

Milner-White, E. James and Rycroft, David S. (1983) The αβ-methylene analogues of ADP and ATP act as substrates for creatine kinase: ΔG0 for this reaction and for the hydrolysis of the αβ-methylene analogue of ATP. European Journal of Biochemistry, 133(1), pp. 169-172. (doi: 10.1111/j.1432-1033.1983.tb07443.x) (PMID:6852021)

Milner-White, E. James and Rycroft, David S. (1977) Phosphorus nuclear-magnetic-resonance studies of a transition-state analogue complex of creatine kinase. Biochemical Journal : Molecular Aspects, 167(3), pp. 827-829. (doi: 10.1042/bj1670827) (PMID:603637)

Milner-White, E J. and Spain, P G (1972) Quaternary structure of helical proteins with globular subunits. Biochemical Journal, 130(1), 17P. (doi: 10.1042/bj1300017Pa) (PMCID:PMC1174362)

This list was generated on Mon Jun 16 00:58:24 2025 BST.

Additional information

Grant Advisory Board

  • 2006 - present: European Bioinformatics Institute - Adviser for the Macromolecule Structure Database

Invited International Presentations

  • 2010: Max Planck Institute, Leipzig, Germany - Meeting on "Solvation of Biomolecules", Talk on "Anion and cation binding in proteins"
  • 2010: Durham University, UK - Meeting on "Prebiotic Evolution". Talk on "Peptide structures in early evolution".
  • 2008: Cambridge, UK - Talk at Cambridge University Biochemistry Dept., on "Helicases"
  • 2008: Cambridge, England - Cambridge University, Biochemistry Dept, UK Amyloid Formation
  • 2008: Grenoble, France - IBS, Grenoble, Amyloid Formation
  • 2008: Naples, Italy - Frederico II University, Amyloid Formation
  • 2007: University of Firenze, Florence, Italy - "Amyloid Formation"
  • 2007: University of Dundee, Dundee, Scotland - "Amyloid Formation"
  • 2007: Ferrara, Italy - "Rotational Effects in Polypeptides" at the University of Ferrara
  • 2006: Louvain, Belgium - ECM23 Symposium, Amyloid formation
  • 2006: Edinburgh, Scotland - Amyloid formation, University of Edinburgh
  • 2006: Manchester, England - Anion and cation binding in proteins, University of Manchester
  • 2006: East Anglia, England - Amyloid formation, University of East Anglia
  • 2006: Ferrara, Italy - Anion and cation binding in proteins, University of Ferrara
  • 2004: Cambridge, England - Cambridge University, EMBO Lecture Course - 3D Structure Databases - Uses for Biological Problem solving
  • 2003: Koln, Germany - University of Koln, lecture
  • 2003: Madison, Wisconsin, USA - University of Wisconsin-Madison, Lecture
  • 2003: EBI, Cambridge, England - Lecture
  • 2002: Padua, Italy - Universities of Frederico II Naples, degli studi Padua, lecture
  • 2001: Freiburg, Germany - University of Freiburg, lecture
  • 2001: Jena, Germany - IMB, lecture
  • 2001: Bern, Switzerland - University of Bern, lecture
  • 2001: Hamburg, Germany - EMBL, lecture

Prizes, Awards and Distinctions

  • 2005: Contributor to European Bioinformatics Institute's Macromolecule Structure Database (MSD) website: http://www.ebi.ac.uk/msd-srv/msdmotif/