Professor Dominic Meek
- Honorary Professor (School of Molecular Biosciences)
Publications
2024
Young, Peter, Greer, Andrew I.M. ORCID: https://orcid.org/0000-0003-2817-5884, Smith, Carol-Anne
ORCID: https://orcid.org/0000-0003-3461-7407, Silverwood, Robert, Tsimbouri, Penelope M.
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, Dominic, Goodyear, Carl, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2024)
Titanium surface synergy: strontium incorporation and controlled disorder nanotopography optimise osteoinduction.
ACS Applied Materials and Interfaces, 16(46),
pp. 63129-63141.
(doi: 10.1021/acsami.4c04117)
(PMID:39509174)
Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0)
Jenkinson, Mark R.J., Meek, Dominic R.M., Tate, Rothwelle, Brady, Adrian, MacMillan, Sandy, Grant, Helen and Currie, Susan (2024) Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. Bone and Joint Journal, 106-B(3A), pp. 51-58. (doi: 10.1302/0301-620X.106B3.BJJ-2023-0814.R1) (PMID:38423080)
2023
Magan, Ahmed A., Radhakrishnan, Ganan T., Kayani, Babar, Ronca, Flaminia, Khanduja, Vikas, Meek, Robert M.D. and Haddad, Fares S. (2023) Time for return to sport following total hip arthroplasty: a meta-analysis. HIP International, 33(2), pp. 221-230. (doi: 10.1177/11207000211041975) (PMID:34538122)
2022
Xiao, Yinbo, Donnelly, Hannah ORCID: https://orcid.org/0000-0002-5154-9971, Sprott, Mark
ORCID: https://orcid.org/0000-0002-1990-9498, Luo, Jiajun, Jayawarna, Vineetha, Lemgruber, Leandro
ORCID: https://orcid.org/0000-0003-2832-6806, Tsimbouri, P. Monica
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, R.M. Dominic, Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2022)
Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis.
Materials Today Bio, 16,
100367.
(doi: 10.1016/j.mtbio.2022.100367)
(PMID:35937570)
(PMCID:PMC9352550)
Mcvey, Lindsey, Kane, Nicholas, Murray, Helen, Meek, R.M. Dominic and Ahmed, Syed Faisal ORCID: https://orcid.org/0000-0003-0689-5549
(2022)
Elective hip arthroplasty rates and related complications in people with diabetes mellitus.
HIP International, 32(6),
pp. 717-723.
(doi: 10.1177/1120700020981573)
(PMID:33334203)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
2020
Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
2018
Marsh, A. G., Nisar, A., El Refai, M., Patil, S. and Meek, R. M. D. (2018) Can we predict which dysplastic hips will require acetabular augmentation during total hip arthroplasty based on pre-operative radiographs? Bone and Joint Journal, 99-B(4), pp. 445-450. (doi: 10.1302/0301-620x.99b4.bjj-2016-0041.r1) (PMID:28385932)
Allan, Christopher, Ker, Andrew, Smith, Carol-Anne ORCID: https://orcid.org/0000-0003-3461-7407, Tsimbouri, Penelope
ORCID: https://orcid.org/0000-0001-5124-7458, Borsoi, Juliana, O'Neill, Stewart, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Meek, Dominic
(2018)
Osteoblast response to disordered nanotopography.
Journal of Tissue Engineering, 9,
pp. 1-7.
(doi: 10.1177/2041731418784098)
(PMID:30034770)
(PMCID:PMC6048666)
2017
Ballester-Beltrán, José, Trujillo Munoz, Sara ORCID: https://orcid.org/0000-0002-5449-3782, Alakpa, Enateri V., Compañ, Vicente, Gavara, Rafael, Meek, Dominic, West, Christopher C., Péault, Bruno, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100
(2017)
Confined sandwichlike microenvironments tune myogenic differentiation.
ACS Biomaterials Science and Engineering, 3(8),
pp. 1710-1718.
(doi: 10.1021/acsbiomaterials.7b00109)
(PMID:28824958)
(PMCID:PMC5558191)
Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)
Donnelly, Hannah ORCID: https://orcid.org/0000-0002-5154-9971, Smith, Carol-Anne
ORCID: https://orcid.org/0000-0003-3461-7407, Sweeten, Paula E., Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X, Meek, Dominic, D'Este, Matteo, Mata, Alvaro, Eglin, David and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2017)
Bone and cartilage differentiation of a single stem cell population driven by material interface.
Journal of Tissue Engineering, 8,
pp. 1-10.
(doi: 10.1177/2041731417705615)
(PMID:28567273)
(PMCID:PMC5438107)
2016
Davison, Martin J., McMurray, Rebecca J., Smith, Carol-Anne ORCID: https://orcid.org/0000-0003-3461-7407, Dalby, Matthew
ORCID: https://orcid.org/0000-0002-0528-3359 and Meek, R.M. Dominic
(2016)
Nanopit-induced osteoprogenitor cell differentiation: the effect of nanopit death.
Journal of Tissue Engineering, 7,
pp. 1-8.
(doi: 10.1177/2041731416652778)
(PMID:27298716)
2015
Stipetic, Laurence H., Hamilton, Graham, Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359, Davies, Robert L.
ORCID: https://orcid.org/0000-0002-6342-2222, Meek, R.M. Dominic, Ramage, Gordon
ORCID: https://orcid.org/0000-0002-0932-3514, Smith, David G.E. and Burgess, Karl E.V.
(2015)
Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip.
Genome Announcements, 3(2),
e00336-15.
(doi: 10.1128/genomeA.00336-15)
(PMID:25931597)
(PMCID:PMC4417693)
2014
Halai, Mansur, Ker, Andrew, Meek, R.M. Dominic, Nadeem, Danish, Sjostrom, Terje, Su, Bo, McNamara, Laura E., Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359 and Young, Peter S.
(2014)
Scanning electron microscopical observation of an osteoblast/osteoclast co-culture on micropatterned orthopaedic ceramics.
Journal of Tissue Engineering, 5,
(doi: 10.1177/2041731414552114)
(PMID:25383174)
(PMCID:PMC4221946)
McNamara, Laura E., Sjostrom, Terje, Seunarine, Krishna, Meek, R.M. Dominic, Su, Bo and Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Investigation of the limits of nanoscale filopodial interactions.
Journal of Tissue Engineering, 5,
p. 2041731414536177.
(doi: 10.1177/2041731414536177)
(PMID:24904726)
(PMCID:PMC4046805)
Yang, Jingli, McNamara, Laura E., Gadegaard, Nikolaj ORCID: https://orcid.org/0000-0002-3396-846X, Alakpa, Enateri V., Burgess, Karl V., Meek, Dominic and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs.
ACS Nano, 8(10),
pp. 9941-9953.
(doi: 10.1021/nn504767g)
(PMID:25227207)
2012
Maclaine, S.E., Gadhari, N., Pugin, R., Meek, R.M.D., Liley, M. and Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359
(2012)
Optimizing the osteogenicity of nanotopography using block co-polymer phase separation fabrication techniques.
Journal of Orthopaedic Research, 30(8),
pp. 1190-1197.
(doi: 10.1002/jor.22076)
2011
McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)
Wilkinson, Andrew, Hewitt, Rachael N., McNamara, Laura E., McCloy, David, Meek, R.M. Dominic and Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Biomimetic microtopography to enhance osteogenesis in vitro.
Acta Biomaterialia, 7(7),
pp. 2919-2925.
(doi: 10.1016/j.actbio.2011.03.026)
(PMID:21459166)
2009
Ogunwale, Bamikole, Schmidt-Ott, Andreas, Meek, R. M. Dominic and Brewer, James M. ORCID: https://orcid.org/0000-0001-7933-0915
(2009)
Investigating the immunologic effects of CoCr nanoparticles.
Clinical Orthopaedics and Related Research, 467(11),
3010.
(doi: 10.1007/s11999-009-0949-9)
(PMID:19565304)
(PMCID:PMC2758989)
Articles
Young, Peter, Greer, Andrew I.M. ORCID: https://orcid.org/0000-0003-2817-5884, Smith, Carol-Anne
ORCID: https://orcid.org/0000-0003-3461-7407, Silverwood, Robert, Tsimbouri, Penelope M.
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, Dominic, Goodyear, Carl, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2024)
Titanium surface synergy: strontium incorporation and controlled disorder nanotopography optimise osteoinduction.
ACS Applied Materials and Interfaces, 16(46),
pp. 63129-63141.
(doi: 10.1021/acsami.4c04117)
(PMID:39509174)
Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0)
Jenkinson, Mark R.J., Meek, Dominic R.M., Tate, Rothwelle, Brady, Adrian, MacMillan, Sandy, Grant, Helen and Currie, Susan (2024) Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. Bone and Joint Journal, 106-B(3A), pp. 51-58. (doi: 10.1302/0301-620X.106B3.BJJ-2023-0814.R1) (PMID:38423080)
Magan, Ahmed A., Radhakrishnan, Ganan T., Kayani, Babar, Ronca, Flaminia, Khanduja, Vikas, Meek, Robert M.D. and Haddad, Fares S. (2023) Time for return to sport following total hip arthroplasty: a meta-analysis. HIP International, 33(2), pp. 221-230. (doi: 10.1177/11207000211041975) (PMID:34538122)
Xiao, Yinbo, Donnelly, Hannah ORCID: https://orcid.org/0000-0002-5154-9971, Sprott, Mark
ORCID: https://orcid.org/0000-0002-1990-9498, Luo, Jiajun, Jayawarna, Vineetha, Lemgruber, Leandro
ORCID: https://orcid.org/0000-0003-2832-6806, Tsimbouri, P. Monica
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, R.M. Dominic, Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2022)
Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis.
Materials Today Bio, 16,
100367.
(doi: 10.1016/j.mtbio.2022.100367)
(PMID:35937570)
(PMCID:PMC9352550)
Mcvey, Lindsey, Kane, Nicholas, Murray, Helen, Meek, R.M. Dominic and Ahmed, Syed Faisal ORCID: https://orcid.org/0000-0003-0689-5549
(2022)
Elective hip arthroplasty rates and related complications in people with diabetes mellitus.
HIP International, 32(6),
pp. 717-723.
(doi: 10.1177/1120700020981573)
(PMID:33334203)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
Marsh, A. G., Nisar, A., El Refai, M., Patil, S. and Meek, R. M. D. (2018) Can we predict which dysplastic hips will require acetabular augmentation during total hip arthroplasty based on pre-operative radiographs? Bone and Joint Journal, 99-B(4), pp. 445-450. (doi: 10.1302/0301-620x.99b4.bjj-2016-0041.r1) (PMID:28385932)
Allan, Christopher, Ker, Andrew, Smith, Carol-Anne ORCID: https://orcid.org/0000-0003-3461-7407, Tsimbouri, Penelope
ORCID: https://orcid.org/0000-0001-5124-7458, Borsoi, Juliana, O'Neill, Stewart, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Meek, Dominic
(2018)
Osteoblast response to disordered nanotopography.
Journal of Tissue Engineering, 9,
pp. 1-7.
(doi: 10.1177/2041731418784098)
(PMID:30034770)
(PMCID:PMC6048666)
Ballester-Beltrán, José, Trujillo Munoz, Sara ORCID: https://orcid.org/0000-0002-5449-3782, Alakpa, Enateri V., Compañ, Vicente, Gavara, Rafael, Meek, Dominic, West, Christopher C., Péault, Bruno, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100
(2017)
Confined sandwichlike microenvironments tune myogenic differentiation.
ACS Biomaterials Science and Engineering, 3(8),
pp. 1710-1718.
(doi: 10.1021/acsbiomaterials.7b00109)
(PMID:28824958)
(PMCID:PMC5558191)
Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)
Donnelly, Hannah ORCID: https://orcid.org/0000-0002-5154-9971, Smith, Carol-Anne
ORCID: https://orcid.org/0000-0003-3461-7407, Sweeten, Paula E., Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X, Meek, Dominic, D'Este, Matteo, Mata, Alvaro, Eglin, David and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2017)
Bone and cartilage differentiation of a single stem cell population driven by material interface.
Journal of Tissue Engineering, 8,
pp. 1-10.
(doi: 10.1177/2041731417705615)
(PMID:28567273)
(PMCID:PMC5438107)
Davison, Martin J., McMurray, Rebecca J., Smith, Carol-Anne ORCID: https://orcid.org/0000-0003-3461-7407, Dalby, Matthew
ORCID: https://orcid.org/0000-0002-0528-3359 and Meek, R.M. Dominic
(2016)
Nanopit-induced osteoprogenitor cell differentiation: the effect of nanopit death.
Journal of Tissue Engineering, 7,
pp. 1-8.
(doi: 10.1177/2041731416652778)
(PMID:27298716)
Stipetic, Laurence H., Hamilton, Graham, Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359, Davies, Robert L.
ORCID: https://orcid.org/0000-0002-6342-2222, Meek, R.M. Dominic, Ramage, Gordon
ORCID: https://orcid.org/0000-0002-0932-3514, Smith, David G.E. and Burgess, Karl E.V.
(2015)
Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip.
Genome Announcements, 3(2),
e00336-15.
(doi: 10.1128/genomeA.00336-15)
(PMID:25931597)
(PMCID:PMC4417693)
Halai, Mansur, Ker, Andrew, Meek, R.M. Dominic, Nadeem, Danish, Sjostrom, Terje, Su, Bo, McNamara, Laura E., Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359 and Young, Peter S.
(2014)
Scanning electron microscopical observation of an osteoblast/osteoclast co-culture on micropatterned orthopaedic ceramics.
Journal of Tissue Engineering, 5,
(doi: 10.1177/2041731414552114)
(PMID:25383174)
(PMCID:PMC4221946)
McNamara, Laura E., Sjostrom, Terje, Seunarine, Krishna, Meek, R.M. Dominic, Su, Bo and Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Investigation of the limits of nanoscale filopodial interactions.
Journal of Tissue Engineering, 5,
p. 2041731414536177.
(doi: 10.1177/2041731414536177)
(PMID:24904726)
(PMCID:PMC4046805)
Yang, Jingli, McNamara, Laura E., Gadegaard, Nikolaj ORCID: https://orcid.org/0000-0002-3396-846X, Alakpa, Enateri V., Burgess, Karl V., Meek, Dominic and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs.
ACS Nano, 8(10),
pp. 9941-9953.
(doi: 10.1021/nn504767g)
(PMID:25227207)
Maclaine, S.E., Gadhari, N., Pugin, R., Meek, R.M.D., Liley, M. and Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359
(2012)
Optimizing the osteogenicity of nanotopography using block co-polymer phase separation fabrication techniques.
Journal of Orthopaedic Research, 30(8),
pp. 1190-1197.
(doi: 10.1002/jor.22076)
McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)
Wilkinson, Andrew, Hewitt, Rachael N., McNamara, Laura E., McCloy, David, Meek, R.M. Dominic and Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Biomimetic microtopography to enhance osteogenesis in vitro.
Acta Biomaterialia, 7(7),
pp. 2919-2925.
(doi: 10.1016/j.actbio.2011.03.026)
(PMID:21459166)
Ogunwale, Bamikole, Schmidt-Ott, Andreas, Meek, R. M. Dominic and Brewer, James M. ORCID: https://orcid.org/0000-0001-7933-0915
(2009)
Investigating the immunologic effects of CoCr nanoparticles.
Clinical Orthopaedics and Related Research, 467(11),
3010.
(doi: 10.1007/s11999-009-0949-9)
(PMID:19565304)
(PMCID:PMC2758989)
Research datasets
2021
Kennedy, J., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P., Reid, S., Young, P., Meek, D., Goodyear, C. and Dalby, M. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. [Data Collection]
2016
Lee, L., Gadegaard, N. , Andrés, M. C. d., Turner, L.-A., Burgess, K., Yarwood, S., Wells, J., Mpoyi, E., Salmerón-Sánchez, M., Meek, R. D., Oreffo, R. and Dalby, M. (2016) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. [Data Collection] (Unpublished)