Professor Iain Johnstone

  • Professor (Life Sciences Biomolecular Sciences)
  • Associate (Institute of Molecular Cell & Systems Biology)

telephone: 01413302844
email: Iain.Johnstone@glasgow.ac.uk

Personal assistant: Miss Jennifer Greer
telephone: 0141 330 3562
email: Jennifer.Greer@glasgow.ac.uk

Research interests

  • Tissue specific control of the cell cycle in C. elegans
  • Collagen biogenesis and the recognition and processing of mutant collagens in C. elegans

Read more about Dr Johnstone's research interests.


Publications

List by: Type | Date

Jump to: 2010 | 2009 | 2008 | 2007 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1994 | 1992 | 1991 | 1990 | 1985
Number of items: 28.

2010

Segref, A., Cabello, J., Clucas, C., Schnabel, R. and Johnstone, I. L. (2010) Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine. Molecular Biology of the Cell, 21(5), pp. 725-738. (doi:10.1091/mbc.E09-04-0268)

2009

Thein, M. C., Winter, A. D., Stepek, G., McCormack, G., Stapleton, G., Johnstone, I. L. and Page, A. P. (2009) Combined extracellular matrix cross-linking activity of the peroxidase MLT-7 and the dual oxidase BLI-3 is critical for post-embryonic viability in Caenorhabditis elegans. Journal of Biological Chemistry, 284(26), pp. 17549-17563. (doi:10.1074/jbc.M900831200)

2008

Longman, D., Arrisi, P., Johnstone, I.L. and Cáceres, J.F. (2008) Nonsense‐mediated mRNA decay in Caenorhabditis elegans. In: RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways. Series: Methods in Enzymology, 449. Academic Press, p. 149. ISBN 9780123745842 (doi:10.1016/S0076-6879(08)02407-5)

2007

Longman, D., Plasterk, R., Johnstone, I. and Caceres, J. (2007) Mechanistic insights and identification of two novel factors in the C-elegans NMD pathway. Genes and Development, 21, pp. 1075-1085. (doi:10.1101/gad.417707)

2003

Longman, D., Johnstone, I. L. and Caceres, J. F. (2003) The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA, 9, pp. 881-891. (doi:10.1261/rna.5420503)

McCracken, S., Longman, D., Johnstone, I., Caceres, J. and Blencowe, B. (2003) An evolutionarily conserved role for SRm160 in 3 '-end processing that functions independently of exon junction complex formation. Journal of Biological Chemistry, 278, pp. 44153-44160. (doi:10.1074/jbc.M306856200)

McMahon, L., Muriel, J., Roberts, B., Quinn, M. and Johnstone, I. (2003) Two sets of interacting collagens form functionally distinct substructures within a Caenorhabditis elegans extracellular matrix. Molecular Biology of the Cell, 14, pp. 1366-1378. (doi:10.1091/mbc.E02-08-0479)

Muriel, J., Brannan, M., Taylor, K., Johnstone, I., Lithgow, G. and Tuckwell, D. (2003) M142.2 (cut-6), a novel Caenorhabditis elegans matrix gene important for dauer body shape. Developmental Biology, 260, pp. 339-351. (doi:10.1016/S0012-1606(03)00237-9)

Roberts, B., Clucas, C. and Johnstone, I. (2003) Loss of SEC-23 in Caenorhabditis elegans causes defects in oogenesis, morphogenesis, and extracellular matrix secretion. Molecular Biology of the Cell, 14, pp. 4414-4426.

Thein, M., McCormack, G., Winter, A., Johnstone, I., Shoemaker, C. and Page, A. (2003) Caenorhabditis elegans exoskeleton collagen COL-19: An adult-specific marker for collagen modification and assembly, and the analysis of organismal morphology. Developmental Dynamics, 226, pp. 523-539. (doi:10.1002/dvdy.10259)

2002

Clucas, C. , Cabello, J., Bussing, I., Schnabel, R. and Johnstone, I.L. (2002) Oncogenic potential of a C.elegans cdc25 gene is demonstrated by a gain-of-function allele. EMBO Journal, 21, pp. 665-674.

2001

Longman, D., McGarvey, T., McCracken, S., Johnstone, I., Blencowe, B. and Caceres, J. (2001) Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C-elegans. Current Biology, 11, pp. 1923-1933.

Redmond, D., Clucas, C. , Johnstone, I. and Knox, D. (2001) Expression of Haemonchus contortus pepsinogen in Caenorhabditis elegans. Molecular and Biochemical Parasitology, 112, pp. 125-131.

2000

Ozanne, B. W., McGarry, L., Spence, H. J., Johnstone, I., Winnie, J., Meagher, L. and Stapleton, G. (2000) Transcriptional regulation of cell invasion: AP-1 regulation of a multigenic invasion programme. European Journal of Cancer, 36(13), pp. 1640-1648. (doi:10.1016/S0959-8049(00)00175-1) (PMID:10959050)

Longman, D., Johnstone, I. L. and Cáceres, J. F. (2000) Functional characterization of SR and SR-related genes in Caenorhabditis elegans. EMBO Journal, 19(7), pp. 1625-1637. (doi:10.1093/emboj/19.7.1625) (PMID:10747030) (PMCID:PMC310231)

Johnstone, I. L. (2000) Cuticle collagen genes. expression in Caenorhabditis elegans. Trends in Genetics, 16(1), pp. 21-27. (doi:10.1016/S0168-9525(99)01857-0) (PMID:10637627)

1999

Johnstone, I. L. (1999) Molecular biology. In: Hope, I. A. (ed.) Caenorhabditis elegans: a Practical Approach. Series: Practical approach series (213). Oxford University Press: Oxford ; New York, pp. 201-226. ISBN 9780199637386

1998

Britton, C. , McKerrow, J. H. and Johnstone, I. L. (1998) Regulation of the Caenorhabditis elegans gut cysteine protease gene cpr-1: requirement for GATA motifs. Journal of Molecular Biology, 283(1), pp. 15-27. (doi:10.1006/jmbi.1998.2093) (PMID:9761670)

1997

Gilleard, J. S., Barry, J. D. and Johnstone, I. L. (1997) cis regulatory requirements for hypodermal cell-specific expression of the Caenorhabditis elegans cuticle collagen gene dpy-7. Molecular and Cellular Biology, 17(4), pp. 2301-2311. (doi:10.1128/MCB.17.4.2301) (PMID:9121480) (PMCID:PMC232079)

1996

Johnstone, I. L., Shafi, Y., Majeed, A. and Barry, J. D. (1996) Cuticular collagen genes from the parasitic nematode Ostertagia circumcincta. Molecular and Biochemical Parasitology, 80(1), pp. 103-112. (doi:10.1016/0166-6851(96)02682-5) (PMID:8885226)

Johnstone, I. L. and Barry, J. D. (1996) Temporal reiteration of a precise gene expression pattern during nematode development. EMBO Journal, 15(14), pp. 3633-3639. (PMID:8670866) (PMCID:PMC451985)

Larminie, C. G.C. and Johnstone, I. L. (1996) Isolation and characterization of four developmentally regulated cathepsin B-like cysteine protease genes from the nematode Caenorhabditis elegans. DNA and Cell Biology, 15(1), pp. 75-82. (doi:10.1089/dna.1996.15.75) (PMID:8561899)

1994

Johnstone, I. L. (1994) The cuticle of the nematode Caenorhabditis elegans: a complex collagen structure. BioEssays, 16(3), pp. 171-178. (doi:10.1002/bies.950160307) (PMID:8166670)

1992

Johnstone, I.L., Shafi, Y. and Barry, J.D. (1992) Molecular analysis of mutations in the Caenorhabditis elegans collagen gene dpy-7. EMBO Journal, 11(11), pp. 3857-3863. (PMID:1396579) (PMCID:PMC556895)

1991

Gems, D., Johnstone, I. L. and Clutterbuck, A. J. (1991) An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency. Gene, 98(1), pp. 61-67. (doi:10.1016/0378-1119(91)90104-J) (PMID:2013411)

1990

Johnstone, I.L., McCabe, P.C., Greaves, P., Gurr, S.J., Cole, G.E., Brow, M.A., Unkles, S.E., Clutterbuck, A.J., Kinghorn, J.R. and Innis, M.A. (1990) Isolation and characterisation of the crnA-niiA-niaD gene cluster for nitrate assimilation in Aspergillus nidulans. Gene, 90(2), pp. 181-192. (doi:10.1016/0378-1119(90)90178-T) (PMID:2205530)

1985

Johnstone, I. (1985) Transformation of Aspergillus nidulans. Microbiological Sciences, 2(10), pp. 307-311. (PMID:3939985)

Johnstone, I.L., Hughes, S.G. and Clutterbuck, A.J. (1985) Cloning an Aspergillus nidulans developmental gene by transformation. EMBO Journal, 4(5), pp. 1307-1311. (PMID:3891328) (PMCID:PMC554341)

This list was generated on Wed Nov 20 16:35:53 2019 GMT.
Number of items: 28.

Articles

Segref, A., Cabello, J., Clucas, C., Schnabel, R. and Johnstone, I. L. (2010) Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine. Molecular Biology of the Cell, 21(5), pp. 725-738. (doi:10.1091/mbc.E09-04-0268)

Thein, M. C., Winter, A. D., Stepek, G., McCormack, G., Stapleton, G., Johnstone, I. L. and Page, A. P. (2009) Combined extracellular matrix cross-linking activity of the peroxidase MLT-7 and the dual oxidase BLI-3 is critical for post-embryonic viability in Caenorhabditis elegans. Journal of Biological Chemistry, 284(26), pp. 17549-17563. (doi:10.1074/jbc.M900831200)

Longman, D., Plasterk, R., Johnstone, I. and Caceres, J. (2007) Mechanistic insights and identification of two novel factors in the C-elegans NMD pathway. Genes and Development, 21, pp. 1075-1085. (doi:10.1101/gad.417707)

Longman, D., Johnstone, I. L. and Caceres, J. F. (2003) The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA, 9, pp. 881-891. (doi:10.1261/rna.5420503)

McCracken, S., Longman, D., Johnstone, I., Caceres, J. and Blencowe, B. (2003) An evolutionarily conserved role for SRm160 in 3 '-end processing that functions independently of exon junction complex formation. Journal of Biological Chemistry, 278, pp. 44153-44160. (doi:10.1074/jbc.M306856200)

McMahon, L., Muriel, J., Roberts, B., Quinn, M. and Johnstone, I. (2003) Two sets of interacting collagens form functionally distinct substructures within a Caenorhabditis elegans extracellular matrix. Molecular Biology of the Cell, 14, pp. 1366-1378. (doi:10.1091/mbc.E02-08-0479)

Muriel, J., Brannan, M., Taylor, K., Johnstone, I., Lithgow, G. and Tuckwell, D. (2003) M142.2 (cut-6), a novel Caenorhabditis elegans matrix gene important for dauer body shape. Developmental Biology, 260, pp. 339-351. (doi:10.1016/S0012-1606(03)00237-9)

Roberts, B., Clucas, C. and Johnstone, I. (2003) Loss of SEC-23 in Caenorhabditis elegans causes defects in oogenesis, morphogenesis, and extracellular matrix secretion. Molecular Biology of the Cell, 14, pp. 4414-4426.

Thein, M., McCormack, G., Winter, A., Johnstone, I., Shoemaker, C. and Page, A. (2003) Caenorhabditis elegans exoskeleton collagen COL-19: An adult-specific marker for collagen modification and assembly, and the analysis of organismal morphology. Developmental Dynamics, 226, pp. 523-539. (doi:10.1002/dvdy.10259)

Clucas, C. , Cabello, J., Bussing, I., Schnabel, R. and Johnstone, I.L. (2002) Oncogenic potential of a C.elegans cdc25 gene is demonstrated by a gain-of-function allele. EMBO Journal, 21, pp. 665-674.

Longman, D., McGarvey, T., McCracken, S., Johnstone, I., Blencowe, B. and Caceres, J. (2001) Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C-elegans. Current Biology, 11, pp. 1923-1933.

Redmond, D., Clucas, C. , Johnstone, I. and Knox, D. (2001) Expression of Haemonchus contortus pepsinogen in Caenorhabditis elegans. Molecular and Biochemical Parasitology, 112, pp. 125-131.

Ozanne, B. W., McGarry, L., Spence, H. J., Johnstone, I., Winnie, J., Meagher, L. and Stapleton, G. (2000) Transcriptional regulation of cell invasion: AP-1 regulation of a multigenic invasion programme. European Journal of Cancer, 36(13), pp. 1640-1648. (doi:10.1016/S0959-8049(00)00175-1) (PMID:10959050)

Longman, D., Johnstone, I. L. and Cáceres, J. F. (2000) Functional characterization of SR and SR-related genes in Caenorhabditis elegans. EMBO Journal, 19(7), pp. 1625-1637. (doi:10.1093/emboj/19.7.1625) (PMID:10747030) (PMCID:PMC310231)

Johnstone, I. L. (2000) Cuticle collagen genes. expression in Caenorhabditis elegans. Trends in Genetics, 16(1), pp. 21-27. (doi:10.1016/S0168-9525(99)01857-0) (PMID:10637627)

Britton, C. , McKerrow, J. H. and Johnstone, I. L. (1998) Regulation of the Caenorhabditis elegans gut cysteine protease gene cpr-1: requirement for GATA motifs. Journal of Molecular Biology, 283(1), pp. 15-27. (doi:10.1006/jmbi.1998.2093) (PMID:9761670)

Gilleard, J. S., Barry, J. D. and Johnstone, I. L. (1997) cis regulatory requirements for hypodermal cell-specific expression of the Caenorhabditis elegans cuticle collagen gene dpy-7. Molecular and Cellular Biology, 17(4), pp. 2301-2311. (doi:10.1128/MCB.17.4.2301) (PMID:9121480) (PMCID:PMC232079)

Johnstone, I. L., Shafi, Y., Majeed, A. and Barry, J. D. (1996) Cuticular collagen genes from the parasitic nematode Ostertagia circumcincta. Molecular and Biochemical Parasitology, 80(1), pp. 103-112. (doi:10.1016/0166-6851(96)02682-5) (PMID:8885226)

Johnstone, I. L. and Barry, J. D. (1996) Temporal reiteration of a precise gene expression pattern during nematode development. EMBO Journal, 15(14), pp. 3633-3639. (PMID:8670866) (PMCID:PMC451985)

Larminie, C. G.C. and Johnstone, I. L. (1996) Isolation and characterization of four developmentally regulated cathepsin B-like cysteine protease genes from the nematode Caenorhabditis elegans. DNA and Cell Biology, 15(1), pp. 75-82. (doi:10.1089/dna.1996.15.75) (PMID:8561899)

Johnstone, I. L. (1994) The cuticle of the nematode Caenorhabditis elegans: a complex collagen structure. BioEssays, 16(3), pp. 171-178. (doi:10.1002/bies.950160307) (PMID:8166670)

Johnstone, I.L., Shafi, Y. and Barry, J.D. (1992) Molecular analysis of mutations in the Caenorhabditis elegans collagen gene dpy-7. EMBO Journal, 11(11), pp. 3857-3863. (PMID:1396579) (PMCID:PMC556895)

Gems, D., Johnstone, I. L. and Clutterbuck, A. J. (1991) An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency. Gene, 98(1), pp. 61-67. (doi:10.1016/0378-1119(91)90104-J) (PMID:2013411)

Johnstone, I.L., McCabe, P.C., Greaves, P., Gurr, S.J., Cole, G.E., Brow, M.A., Unkles, S.E., Clutterbuck, A.J., Kinghorn, J.R. and Innis, M.A. (1990) Isolation and characterisation of the crnA-niiA-niaD gene cluster for nitrate assimilation in Aspergillus nidulans. Gene, 90(2), pp. 181-192. (doi:10.1016/0378-1119(90)90178-T) (PMID:2205530)

Johnstone, I. (1985) Transformation of Aspergillus nidulans. Microbiological Sciences, 2(10), pp. 307-311. (PMID:3939985)

Johnstone, I.L., Hughes, S.G. and Clutterbuck, A.J. (1985) Cloning an Aspergillus nidulans developmental gene by transformation. EMBO Journal, 4(5), pp. 1307-1311. (PMID:3891328) (PMCID:PMC554341)

Book Sections

Longman, D., Arrisi, P., Johnstone, I.L. and Cáceres, J.F. (2008) Nonsense‐mediated mRNA decay in Caenorhabditis elegans. In: RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways. Series: Methods in Enzymology, 449. Academic Press, p. 149. ISBN 9780123745842 (doi:10.1016/S0076-6879(08)02407-5)

Johnstone, I. L. (1999) Molecular biology. In: Hope, I. A. (ed.) Caenorhabditis elegans: a Practical Approach. Series: Practical approach series (213). Oxford University Press: Oxford ; New York, pp. 201-226. ISBN 9780199637386

This list was generated on Wed Nov 20 16:35:53 2019 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Using C. elegans to identify novel genetic modifiers of collagen IV mutations that cause stroke
    Tenovus Scotland
    2015 - 2015
     
  • Shedding light on oxidative stress: Identifying factors modulating the redox balance in the endoplasmic reticulum of Caenorhabditis elegans.
    Biotechnology and Biological Sciences Research Council
    2013 - 2016
     
  • Identifying factors modulating the redox balance in the endoplasmic reticulum using the model system Carnorhabditis elegans (ISSF Catalyst Fund)
    Wellcome Trust
    2011 - 2014
     
  • A genetic analysis of the response to the presence of glycine substitution mutant collagen in C. elegans
    Medical Research Council
    2006 - 2009
     
  • Tissue specific control of the cell cycle in C. elegans
    Medical Research Council
    2005 - 2008
     
  • A genetic analysis of collagen biogenesis in C.elegans
    Wellcome Trust
    2005 - 2007
     
  • Molecular genetics and biochemistry of parasites
    Medical Research Council
    2004 - 2009
     

Additional information

Grant Advisory Board

  • 2006 - 2009: MRC - College of Experts
  • 1998 - 2003: MRC - Member of Advisory Board

Invited International Presentations

  • 2005: Glasgow, Scotland - Bioscience - co-organiser and co-chair mini symposium "Systematic Functional Analysis of Genomes"
  • 2002: Italy - Invited Speaker at the European Worm Meeting,

Research Fellowship

  • 2004 - 1998: MRC Career Development Fellowship
  • 1998 - 2003: MRC Senior Fellowship