Mr Steven McFarlane

  • Research Project Support (Virology)

telephone: 01413303922
email: Steven.McFarlane@glasgow.ac.uk

MRC-UofG CVR, Sir Michael Stoker Building, Garscube Estate, 464 Bearsden Road. Glasgow, G61 1qh

Import to contacts

Research interests

CVR logo 

Member of the Boutell group.

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2021 | 2020 | 2019 | 2018 | 2016 | 2011
Number of items: 12.

2025

Roberts, A. P.E. et al. (2025) Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription. PLoS Pathogens, 21(8), e1012501. (doi: 10.1371/journal.ppat.1012501) (PMID:40834051) (PMCID:PMC12393724)

2024

Francois, A. K. et al. (2024) Single-genome analysis reveals heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts. mBio, 15(4), e0327823. (doi: 10.1128/mbio.03278-23) (PMID:32753500) (PMCID:PMC7407090)

2023

Montezano, A. C. et al. (2023) SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication. Scientific Reports, 13, 14086. (doi: 10.1038/s41598-023-41115-3) (PMID:37640791) (PMCID:PMC10462711)

2021

Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)

Charman, M. et al. (2021) Constitutive TRIM22 expression in the respiratory tract confers a pre-existing defence against influenza A virus infection. Frontiers in Cellular and Infection Microbiology, 11, 689707. (doi: 10.3389/fcimb.2021.689707) (PMID:34621686) (PMCID:PMC8490869)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

2020

Stokes, Samuel, Almire, Floriane, Tatham, Michael H., McFarlane, Steven, Mertens, Peter, Pondeville, Emilie and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2020) The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells. PLoS Pathogens, 16(12), e1009134. (doi: 10.1371/journal.ppat.1009134) (PMID:33351855) (PMCID:PMC7802965)

2019

McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)

2018

Alandijany, Thamir, Roberts, Ashley P.E., Conn, Kristen L., Loney, Colin ORCID logoORCID: https://orcid.org/0000-0002-0508-1781, McFarlane, Steven, Orr, Anne and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2018) Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection. PLoS Pathogens, 14(1), e1006769. (doi: 10.1371/journal.ppat.1006769) (PMID:29309427) (PMCID:PMC5757968)

2016

Brown, James R., Conn, Kristen L., Wasson, Peter, Charman, Matthew, Tong, Lily, Grant, Kyle, McFarlane, Steven and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2016) The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic antiviral immune response to herpes simplex virus 1 (HSV-1). Journal of Virology, 90, 13. (doi: 10.1128/JVI.00426-16) (PMID:27099310) (PMCID:PMC4907222)

Conn, Kristen L., Wasson, Peter, McFarlane, Steven, Tong, Lily, Brown, James R., Grant, Kyle G., Domingues, Patricia and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2016) A novel role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the restriction of herpes simplex virus 1 (HSV-1) by the cellular intrinsic antiviral immune response. Journal of Virology, 90(9), pp. 4807-4826. (doi: 10.1128/JVI.03055-15) (PMID:26937035)

2011

Boutell, C. ORCID logoORCID: https://orcid.org/0000-0002-2970-7785, Cuchet, D., Vanni, E., Orr, A., Glass, M., McFarlane, S. and Everett, R.D. (2011) A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence. PLoS Pathogens, 7(9), e1002245. (doi: 10.1371/journal.ppat.1002245) (PMID:21949651) (PMCID:PMC3174244)

This list was generated on Mon Nov 3 01:50:54 2025 GMT.
Jump to: Articles
Number of items: 12.

Articles

Roberts, A. P.E. et al. (2025) Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription. PLoS Pathogens, 21(8), e1012501. (doi: 10.1371/journal.ppat.1012501) (PMID:40834051) (PMCID:PMC12393724)

Francois, A. K. et al. (2024) Single-genome analysis reveals heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts. mBio, 15(4), e0327823. (doi: 10.1128/mbio.03278-23) (PMID:32753500) (PMCID:PMC7407090)

Montezano, A. C. et al. (2023) SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication. Scientific Reports, 13, 14086. (doi: 10.1038/s41598-023-41115-3) (PMID:37640791) (PMCID:PMC10462711)

Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)

Charman, M. et al. (2021) Constitutive TRIM22 expression in the respiratory tract confers a pre-existing defence against influenza A virus infection. Frontiers in Cellular and Infection Microbiology, 11, 689707. (doi: 10.3389/fcimb.2021.689707) (PMID:34621686) (PMCID:PMC8490869)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

Stokes, Samuel, Almire, Floriane, Tatham, Michael H., McFarlane, Steven, Mertens, Peter, Pondeville, Emilie and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2020) The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells. PLoS Pathogens, 16(12), e1009134. (doi: 10.1371/journal.ppat.1009134) (PMID:33351855) (PMCID:PMC7802965)

McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)

Alandijany, Thamir, Roberts, Ashley P.E., Conn, Kristen L., Loney, Colin ORCID logoORCID: https://orcid.org/0000-0002-0508-1781, McFarlane, Steven, Orr, Anne and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2018) Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection. PLoS Pathogens, 14(1), e1006769. (doi: 10.1371/journal.ppat.1006769) (PMID:29309427) (PMCID:PMC5757968)

Brown, James R., Conn, Kristen L., Wasson, Peter, Charman, Matthew, Tong, Lily, Grant, Kyle, McFarlane, Steven and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2016) The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic antiviral immune response to herpes simplex virus 1 (HSV-1). Journal of Virology, 90, 13. (doi: 10.1128/JVI.00426-16) (PMID:27099310) (PMCID:PMC4907222)

Conn, Kristen L., Wasson, Peter, McFarlane, Steven, Tong, Lily, Brown, James R., Grant, Kyle G., Domingues, Patricia and Boutell, Chris ORCID logoORCID: https://orcid.org/0000-0002-2970-7785 (2016) A novel role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the restriction of herpes simplex virus 1 (HSV-1) by the cellular intrinsic antiviral immune response. Journal of Virology, 90(9), pp. 4807-4826. (doi: 10.1128/JVI.03055-15) (PMID:26937035)

Boutell, C. ORCID logoORCID: https://orcid.org/0000-0002-2970-7785, Cuchet, D., Vanni, E., Orr, A., Glass, M., McFarlane, S. and Everett, R.D. (2011) A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence. PLoS Pathogens, 7(9), e1002245. (doi: 10.1371/journal.ppat.1002245) (PMID:21949651) (PMCID:PMC3174244)

This list was generated on Mon Nov 3 01:50:54 2025 GMT.

Research datasets

Jump to: 2020
Number of items: 1.

2020

Stokes, S., Almire, F., Tatham, M., McFarlane, S., Mertens, P., Pondeville, E. and Boutell, C. (2020) The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells. [Data Collection]

This list was generated on Mon Nov 3 16:28:59 2025 GMT.