Dr Shikha Shikha
- Research Associate (Parasitology)
Publications
2025
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Tobiasson, Victor, Ferreira Silva, Mariana, Ovciarikova, Jana, Beraldi, Dario, Mühleip, Alexander and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2025)
Numerous rRNA molecules form the apicomplexan mitoribosome via repurposed protein and RNA elements.
Nature Communications, 16,
817.
(doi: 10.1038/s41467-025-56057-9)
Edgar, Rebecca C.S., Hanna, Jack ORCID: https://orcid.org/0000-0002-1302-8905, Novotná, Markéta, Campillo Poveda, Marta
ORCID: https://orcid.org/0000-0002-2561-5429, Rawat, Mukul, Shikha, Shikha
ORCID: https://orcid.org/0000-0002-7878-1463, Venter, Frank and Ridgway, Melanie C.
(2025)
SPPIRIT: a network connecting Scottish early-career researchers in parasitology.
Trends in Parasitology, 41(1),
pp. 8-12.
(doi: 10.1016/j.pt.2024.11.009)
(PMID:39658486)
2024
Ovciarikova, J. et al. (2024) Two ancient membrane pores mediate mitochondrial-nucleus membrane contact sites. Journal of Cell Biology, 223(4), e202304075. (doi: 10.1083/jcb.202304075) (PMID:38456969)
2022
Ovciarikova, Jana, Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463 and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2022)
Nuclear interactions: a spotlight on nuclear mitochondrial membrane contact sites.
Contact, 5,
p. 25152564221096217.
(doi: 10.1177/25152564221096217)
(PMID:36338149)
(PMCID:PMC9623421)
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Ferreira Silva, Mariana and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2022)
Identification and validation of Toxoplasma gondii mitoribosomal large subunit components.
Microorganisms, 10(5),
863.
(doi: 10.3390/microorganisms10050863)
(PMID:35630308)
(PMCID:PMC9145746)
2020
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Huot, Jonathan L, Schneider, Andre and Niemann, Moritz
(2020)
tRNA import across the mitochondrial inner membrane in T. brucei requires TIM subunits but is independent of protein import.
Nucleic Acids Research, 48(21),
pp. 12269-12281.
(doi: 10.1093/nar/gkaa1098)
(PMID:33231678)
(PMCID:PMC7708065)
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463 and Schneider, André
(2020)
The single CCA-adding enzyme of T. brucei has distinct functions in the cytosol and in mitochondria.
Journal of Biological Chemistry, 295(18),
pp. 6138-6150.
(doi: 10.1074/jbc.ra119.011877)
(PMID:32234763)
(PMCID:PMC7196653)
2019
Huot, Jonathan L., Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463 and Schneider, André
(2019)
Inducible orthogonal aminoacylation demonstrates that charging is required for mitochondrial tRNA import in Trypanosoma brucei.
Scientific Reports, 9,
10836.
(doi: 10.1038/s41598-019-47268-4)
(PMID:31346230)
(PMCID:PMC6658472)
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Brogli, Rebecca, Schneider, André and Polacek, Norbert
(2019)
tRNA Biology in Trypanosomes.
CHIMIA International Journal for Chemistry, 73(5),
pp. 395-405.
(doi: 10.2533/chimia.2019.395)
(PMID:31118122)
2015
Kumar, Ashutosh, Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Majhi, Rakesh Kumar, Swain, Nirlipta, Yadav, Manoj and Goswami, Chandan
(2015)
Regulation of TRP channels by steroids: Implications in physiology and diseases.
General and Comparative Endocrinology, 220,
pp. 23-32.
(doi: 10.1016/j.ygcen.2014.10.004)
(PMID:25449179)
Shikha, Kumari ORCID: https://orcid.org/0000-0002-7878-1463, Kumar, Ashutosh, Sardar, Puspendu, Yadav, Manoj, Majhi, Rakesh Kumar, Kumar, Abhishek and Goswami, Chandan
(2015)
Influence of membrane cholesterol in the molecular evolution and functional regulation of TRPV4.
Biochemical and Biophysical Research Communications, 456(1),
pp. 312-319.
(doi: 10.1016/j.bbrc.2014.11.077)
(PMID:25434996)
2014
Pradhan, N. et al. (2014) Induction of apoptosis by Fe(salen)Cl through caspase-dependent pathway specifically in tumor cells: Fe(salen)Cl induces apoptosis in tumor cells. Cell Biology International, 38(10), pp. 1118-1131. (doi: 10.1002/cbin.10308) (PMID:24804954)
2013
Majhi, R. K. et al. (2013) Thermosensitive ion channel TRPV1 is endogenously expressed in the sperm of a fresh water teleost fish (Labeo rohita) and regulates sperm motility. Channels, 7(6), pp. 483-492. 23912940. (doi: 10.4161/chan.25793) (PMID:PMC4042483)
Articles
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Tobiasson, Victor, Ferreira Silva, Mariana, Ovciarikova, Jana, Beraldi, Dario, Mühleip, Alexander and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2025)
Numerous rRNA molecules form the apicomplexan mitoribosome via repurposed protein and RNA elements.
Nature Communications, 16,
817.
(doi: 10.1038/s41467-025-56057-9)
Edgar, Rebecca C.S., Hanna, Jack ORCID: https://orcid.org/0000-0002-1302-8905, Novotná, Markéta, Campillo Poveda, Marta
ORCID: https://orcid.org/0000-0002-2561-5429, Rawat, Mukul, Shikha, Shikha
ORCID: https://orcid.org/0000-0002-7878-1463, Venter, Frank and Ridgway, Melanie C.
(2025)
SPPIRIT: a network connecting Scottish early-career researchers in parasitology.
Trends in Parasitology, 41(1),
pp. 8-12.
(doi: 10.1016/j.pt.2024.11.009)
(PMID:39658486)
Ovciarikova, J. et al. (2024) Two ancient membrane pores mediate mitochondrial-nucleus membrane contact sites. Journal of Cell Biology, 223(4), e202304075. (doi: 10.1083/jcb.202304075) (PMID:38456969)
Ovciarikova, Jana, Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463 and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2022)
Nuclear interactions: a spotlight on nuclear mitochondrial membrane contact sites.
Contact, 5,
p. 25152564221096217.
(doi: 10.1177/25152564221096217)
(PMID:36338149)
(PMCID:PMC9623421)
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Ferreira Silva, Mariana and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2022)
Identification and validation of Toxoplasma gondii mitoribosomal large subunit components.
Microorganisms, 10(5),
863.
(doi: 10.3390/microorganisms10050863)
(PMID:35630308)
(PMCID:PMC9145746)
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Huot, Jonathan L, Schneider, Andre and Niemann, Moritz
(2020)
tRNA import across the mitochondrial inner membrane in T. brucei requires TIM subunits but is independent of protein import.
Nucleic Acids Research, 48(21),
pp. 12269-12281.
(doi: 10.1093/nar/gkaa1098)
(PMID:33231678)
(PMCID:PMC7708065)
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463 and Schneider, André
(2020)
The single CCA-adding enzyme of T. brucei has distinct functions in the cytosol and in mitochondria.
Journal of Biological Chemistry, 295(18),
pp. 6138-6150.
(doi: 10.1074/jbc.ra119.011877)
(PMID:32234763)
(PMCID:PMC7196653)
Huot, Jonathan L., Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463 and Schneider, André
(2019)
Inducible orthogonal aminoacylation demonstrates that charging is required for mitochondrial tRNA import in Trypanosoma brucei.
Scientific Reports, 9,
10836.
(doi: 10.1038/s41598-019-47268-4)
(PMID:31346230)
(PMCID:PMC6658472)
Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Brogli, Rebecca, Schneider, André and Polacek, Norbert
(2019)
tRNA Biology in Trypanosomes.
CHIMIA International Journal for Chemistry, 73(5),
pp. 395-405.
(doi: 10.2533/chimia.2019.395)
(PMID:31118122)
Kumar, Ashutosh, Shikha, Shikha ORCID: https://orcid.org/0000-0002-7878-1463, Majhi, Rakesh Kumar, Swain, Nirlipta, Yadav, Manoj and Goswami, Chandan
(2015)
Regulation of TRP channels by steroids: Implications in physiology and diseases.
General and Comparative Endocrinology, 220,
pp. 23-32.
(doi: 10.1016/j.ygcen.2014.10.004)
(PMID:25449179)
Shikha, Kumari ORCID: https://orcid.org/0000-0002-7878-1463, Kumar, Ashutosh, Sardar, Puspendu, Yadav, Manoj, Majhi, Rakesh Kumar, Kumar, Abhishek and Goswami, Chandan
(2015)
Influence of membrane cholesterol in the molecular evolution and functional regulation of TRPV4.
Biochemical and Biophysical Research Communications, 456(1),
pp. 312-319.
(doi: 10.1016/j.bbrc.2014.11.077)
(PMID:25434996)
Pradhan, N. et al. (2014) Induction of apoptosis by Fe(salen)Cl through caspase-dependent pathway specifically in tumor cells: Fe(salen)Cl induces apoptosis in tumor cells. Cell Biology International, 38(10), pp. 1118-1131. (doi: 10.1002/cbin.10308) (PMID:24804954)
Majhi, R. K. et al. (2013) Thermosensitive ion channel TRPV1 is endogenously expressed in the sperm of a fresh water teleost fish (Labeo rohita) and regulates sperm motility. Channels, 7(6), pp. 483-492. 23912940. (doi: 10.4161/chan.25793) (PMID:PMC4042483)