Dr Megan Sloan
- Research Fellow (Parasitology)
Publications
2025
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Scott, Adam, Aghabi, Dana, Mrvova, Lucia and Harding, Clare R.
ORCID: https://orcid.org/0000-0002-8428-0374
(2025)
Iron-mediated post-transcriptional regulation in Toxoplasma gondii.
PLoS Pathogens, 21(2),
e1012857.
(doi: 10.1371/journal.ppat.1012857)
(PMID:39899594)
(PMCID:PMC11801735)
2024
Maclean, Andrew E., Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Renaud, Eléa A., Argyle, Blythe E., Lewis, William H., Ovciarikova, Jana, Demolombe, Vincent, Waller, Ross F., Besteiro, Sébastien and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2024)
The Toxoplasma gondii mitochondrial transporter ABCB7L is essential for the biogenesis of cytosolic and nuclear iron-sulfur cluster proteins and cytosolic translation.
mBio,
(doi: 10.1128/mbio.00872-24)
(PMID:39207139)
(PMCID:PMC11481526)
(Early Online Publication)
2023
Aghabi, Dana, Sloan, Megan ORCID: https://orcid.org/0000-0001-7659-4069, Gill, Grace, Hartmann, Elena, Antipova, Olga, Dou, Zhicheng, Guerra, Alfredo J., Carruthers, Vern B. and Harding, Clare R.
ORCID: https://orcid.org/0000-0002-8428-0374
(2023)
The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii.
Nature Communications, 14,
3659.
(doi: 10.1038/s41467-023-39436-y)
(PMID:37339985)
(PMCID:PMC10281983)
2021
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Aghabi, Dana and Harding, Clare R.
ORCID: https://orcid.org/0000-0002-8428-0374
(2021)
Orchestrating a heist: uptake and storage of metals by apicomplexan parasites.
Microbiology, 167(12),
001114.
(doi: 10.1099/mic.0.001114)
(PMID:34898419)
(PMCID:PMC7612242)
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Sadlova, Jovana, Lestinova, Tereza, Sanders, Mandy J., Cotton, James A.
ORCID: https://orcid.org/0000-0001-5475-3583, Volf, Petr and Ligoxygakis, Petros
(2021)
The Phlebotomus papatasi systemic transcriptional response to trypanosomatid-contaminated blood does not differ from the non-infected blood meal.
Parasites and Vectors, 14,
15.
(doi: 10.1186/s13071-020-04498-0)
(PMID:33407867)
(PMCID:PMC7789365)
2020
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069 and Ligoxygakis, Petros
(2020)
Tools for the genetic manipulation of Herpetomonas muscarum.
G3: Genes, Genomes, Genetics, 10(5),
pp. 1613-1616.
(doi: 10.1534/g3.120.401048)
(PMID:32205316)
(PMCID:PMC7202032)
2019
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Brooks, Karen, Otto, Thomas D.
ORCID: https://orcid.org/0000-0002-1246-7404, Sanders, Mandy J., Cotton, James A.
ORCID: https://orcid.org/0000-0001-5475-3583 and Ligoxygakis, Petros
(2019)
Transcriptional and genomic parallels between the monoxenous parasite Herpetomonas muscarum and Leishmania.
PLoS Genetics, 15(11),
e1008452.
(doi: 10.1371/journal.pgen.1008452)
(PMID:31710597)
(PMCID:PMC6872171)
Wang, Lihui, Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069 and Ligoxygakis, Petros
(2019)
Intestinal NF-κB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model.
PLoS Genetics, 15(3),
e1007931.
(doi: 10.1371/journal.pgen.1007931)
(PMID:30822306)
(PMCID:PMC6415867)
2017
Alharbi, N. K. et al. (2017) ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice. Vaccine, 35(30), pp. 3780-3788. (doi: 10.1016/j.vaccine.2017.05.032) (PMID:28579232) (PMCID:PMC5516308)
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069 and Ligoxygakis, Petros
(2017)
Immunology of insect vectors: midgut interactions of sandflies and tsetse with kinetoplastid parasites as a paradigm for establishing infection.
In: Ligoxygakis, Petros (ed.)
Insect Immunity.
Series: Advances in insect physiology (52).
Academic Press: Cambridge, MA, pp. 231-248.
ISBN 9780128117750
(doi: 10.1016/bs.aiip.2017.04.003)
2015
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Reaves, Barbara J., Maclean, Mary J., Storey, Bob E. and Wolstenholme, Adrian J.
(2015)
Expression of nicotinic acetylcholine receptor subunits from parasitic nematodes in Caenorhabditis elegans.
Molecular and Biochemical Parasitology, 204(1),
pp. 44-50.
(doi: 10.1016/j.molbiopara.2015.12.006)
(PMID:26747395)
(PMCID:PMC4729587)
2014
Thomas, Benjamin, Sloan, Megan ORCID: https://orcid.org/0000-0001-7659-4069, Wolstenholme, Adrian and Kner, Peter
(2014)
120nm resolution in thick samples with structured illumination and adaptive optics.
In: MEMS Adaptive Optics VIII, San Francisco, CA, USA, 01-06 Feb 2014,
89780H.
ISBN 9780819498915
(doi: 10.1117/12.2040931)
Articles
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Scott, Adam, Aghabi, Dana, Mrvova, Lucia and Harding, Clare R.
ORCID: https://orcid.org/0000-0002-8428-0374
(2025)
Iron-mediated post-transcriptional regulation in Toxoplasma gondii.
PLoS Pathogens, 21(2),
e1012857.
(doi: 10.1371/journal.ppat.1012857)
(PMID:39899594)
(PMCID:PMC11801735)
Maclean, Andrew E., Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Renaud, Eléa A., Argyle, Blythe E., Lewis, William H., Ovciarikova, Jana, Demolombe, Vincent, Waller, Ross F., Besteiro, Sébastien and Sheiner, Lilach
ORCID: https://orcid.org/0000-0001-5909-2307
(2024)
The Toxoplasma gondii mitochondrial transporter ABCB7L is essential for the biogenesis of cytosolic and nuclear iron-sulfur cluster proteins and cytosolic translation.
mBio,
(doi: 10.1128/mbio.00872-24)
(PMID:39207139)
(PMCID:PMC11481526)
(Early Online Publication)
Aghabi, Dana, Sloan, Megan ORCID: https://orcid.org/0000-0001-7659-4069, Gill, Grace, Hartmann, Elena, Antipova, Olga, Dou, Zhicheng, Guerra, Alfredo J., Carruthers, Vern B. and Harding, Clare R.
ORCID: https://orcid.org/0000-0002-8428-0374
(2023)
The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii.
Nature Communications, 14,
3659.
(doi: 10.1038/s41467-023-39436-y)
(PMID:37339985)
(PMCID:PMC10281983)
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Aghabi, Dana and Harding, Clare R.
ORCID: https://orcid.org/0000-0002-8428-0374
(2021)
Orchestrating a heist: uptake and storage of metals by apicomplexan parasites.
Microbiology, 167(12),
001114.
(doi: 10.1099/mic.0.001114)
(PMID:34898419)
(PMCID:PMC7612242)
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Sadlova, Jovana, Lestinova, Tereza, Sanders, Mandy J., Cotton, James A.
ORCID: https://orcid.org/0000-0001-5475-3583, Volf, Petr and Ligoxygakis, Petros
(2021)
The Phlebotomus papatasi systemic transcriptional response to trypanosomatid-contaminated blood does not differ from the non-infected blood meal.
Parasites and Vectors, 14,
15.
(doi: 10.1186/s13071-020-04498-0)
(PMID:33407867)
(PMCID:PMC7789365)
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069 and Ligoxygakis, Petros
(2020)
Tools for the genetic manipulation of Herpetomonas muscarum.
G3: Genes, Genomes, Genetics, 10(5),
pp. 1613-1616.
(doi: 10.1534/g3.120.401048)
(PMID:32205316)
(PMCID:PMC7202032)
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Brooks, Karen, Otto, Thomas D.
ORCID: https://orcid.org/0000-0002-1246-7404, Sanders, Mandy J., Cotton, James A.
ORCID: https://orcid.org/0000-0001-5475-3583 and Ligoxygakis, Petros
(2019)
Transcriptional and genomic parallels between the monoxenous parasite Herpetomonas muscarum and Leishmania.
PLoS Genetics, 15(11),
e1008452.
(doi: 10.1371/journal.pgen.1008452)
(PMID:31710597)
(PMCID:PMC6872171)
Wang, Lihui, Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069 and Ligoxygakis, Petros
(2019)
Intestinal NF-κB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model.
PLoS Genetics, 15(3),
e1007931.
(doi: 10.1371/journal.pgen.1007931)
(PMID:30822306)
(PMCID:PMC6415867)
Alharbi, N. K. et al. (2017) ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice. Vaccine, 35(30), pp. 3780-3788. (doi: 10.1016/j.vaccine.2017.05.032) (PMID:28579232) (PMCID:PMC5516308)
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069, Reaves, Barbara J., Maclean, Mary J., Storey, Bob E. and Wolstenholme, Adrian J.
(2015)
Expression of nicotinic acetylcholine receptor subunits from parasitic nematodes in Caenorhabditis elegans.
Molecular and Biochemical Parasitology, 204(1),
pp. 44-50.
(doi: 10.1016/j.molbiopara.2015.12.006)
(PMID:26747395)
(PMCID:PMC4729587)
Book Sections
Sloan, Megan A. ORCID: https://orcid.org/0000-0001-7659-4069 and Ligoxygakis, Petros
(2017)
Immunology of insect vectors: midgut interactions of sandflies and tsetse with kinetoplastid parasites as a paradigm for establishing infection.
In: Ligoxygakis, Petros (ed.)
Insect Immunity.
Series: Advances in insect physiology (52).
Academic Press: Cambridge, MA, pp. 231-248.
ISBN 9780128117750
(doi: 10.1016/bs.aiip.2017.04.003)
Conference Proceedings
Thomas, Benjamin, Sloan, Megan ORCID: https://orcid.org/0000-0001-7659-4069, Wolstenholme, Adrian and Kner, Peter
(2014)
120nm resolution in thick samples with structured illumination and adaptive optics.
In: MEMS Adaptive Optics VIII, San Francisco, CA, USA, 01-06 Feb 2014,
89780H.
ISBN 9780819498915
(doi: 10.1117/12.2040931)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- An iron lens for translational regulation in Toxoplasma gondii
Wellcome Trust
2022 - 2027