Dr Dagmara McGuinness
- Research Associate (Parasitology)
telephone:
(0) 141 330 5276
email:
Dagmara.McGuinness@glasgow.ac.uk
Wellcome Centre for Molecular Parasitology,, Institute of Infection, Immunity and Inflammation, 120 University Place, G12 8TA
Publications
2024
Nyirenda, J. et al. (2024) Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population. Nature Medicine, (doi: 10.1038/s41591-024-03354-3) (Early Online Publication)
Abrams, S. T. et al. (2024) Damage-associated cellular markers in the clinical and pathogenic profile of vaccine-induced immune thrombotic thrombocytopenia. Journal of Thrombosis and Haemostasis, 22(4), pp. 1145-1153. (doi: 10.1016/j.jtha.2023.12.008) (PMID:38103733)
2023
Nyirenda, J. et al. (2023) Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response. bioRxiv, (doi: 10.1101/2023.11.16.566964)
Craven, Hannah, Erlandsson, Helen, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, McGuinness, David
ORCID: https://orcid.org/0000-0003-2947-2047, Mafra, Denise, Ijaz, Umer Zeeshan
ORCID: https://orcid.org/0000-0001-5780-8551, Bergman, Peter, Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843 and Stenvinkel, Peter
(2023)
A normative microbiome is not restored following kidney transplantation.
Clinical Science, 137(20),
pp. 1563-1575.
(doi: 10.1042/CS20230779)
(PMID:37756543)
Panagiotou, Nikolaos ORCID: https://orcid.org/0000-0003-3157-3285, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Jaminon, Armand M.G., Mees, Barend, Selman, Colin
ORCID: https://orcid.org/0000-0002-8727-0593, Schurgers, Leon and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2023)
Microvesicle-mediated tissue regeneration mitigates the effects of cellular ageing.
Cells, 12(13),
1707.
(doi: 10.3390/cells12131707)
(PMID:37443741)
(PMCID:PMC10340655)
2021
Mulvey, Lorna, Wilkie, Stephen E., Borland, Gillian, Griffiths, Kate, Sinclair, Amy, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Watson, David G. and Selman, Colin
ORCID: https://orcid.org/0000-0002-8727-0593
(2021)
Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice.
Molecular and Cellular Endocrinology, 535,
111376.
(doi: 10.1016/j.mce.2021.111376)
(PMID:34246728)
(PMCID:PMC8417819)
Craven, H. et al. (2021) Socioeconomic position links circulatory microbiota differences with biological age. Scientific Reports, 11, 12629. (doi: 10.1038/s41598-021-92042-0) (PMID:34135381) (PMCID:PMC8209159)
2020
Moxon, C. A. et al. (2020) Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria. Blood Advances, 4(13), pp. 2851-2864. (doi: 10.1182/bloodadvances.2019001258) (PMID:32579667) (PMCID:PMC7362376)
Moxon, Christopher A. ORCID: https://orcid.org/0000-0001-6087-9393, Gibbins, Matthew P.
ORCID: https://orcid.org/0000-0002-7166-044X, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Milner, Danny A. and Marti, Matthias
ORCID: https://orcid.org/0000-0003-1040-9566
(2020)
New insights into malaria pathogenesis.
Annual Review of Pathology: Mechanisms of Disease, 15(1),
pp. 315-343.
(doi: 10.1146/annurev-pathmechdis-012419-032640)
(PMID:31648610)
2019
de Kok, M. J. et al. (2019) The neglectable impact of delayed graft function on long-term graft survival in kidneys donated after circulatory death associates with superior organ resilience. Annals of Surgery, 270(5), pp. 877-883. (doi: 10.1097/SLA.0000000000003515) (PMID:31567503)
2018
Diaz-Albiter, Hector M., Regnault, Clément, Alpizar-Sosa, Edubiel A., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519 and Dillon, Rod J.
(2018)
Non-invasive visualisation and identification of fluorescent.
Wellcome Open Research, 3,
160.
(doi: 10.12688/wellcomeopenres.14910.1)
(PMID:30756095)
(PMCID:PMC6367660)
McGuinness, D. et al. (2018) A molecular signature for delayed graft function. Aging Cell, 17(5), e12825. (doi: 10.1111/acel.12825) (PMID:30094915) (PMCID:PMC6156499)
Lakhdar, Ramzi, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Drost, Ellen M., Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843, Bastos, Ricardo, MacNee, William and Rabinovich, Roberto A.
(2018)
Role of accelerated ageing in limb muscle wasting of patients with COPD.
International Journal of Chronic Obstructive Pulmonary Disease, 13,
pp. 1987-1998.
(doi: 10.2147/COPD.S155952)
(PMID:29970961)
(PMCID:PMC6022820)
2017
Shiels, Paul G. ORCID: https://orcid.org/0000-0002-7577-9843, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Eriksson, Maria, Kooman, Jeroen P. and Stenvinkel, Peter
(2017)
The role of epigenetics in renal ageing.
Nature Reviews Nephrology, 13,
pp. 471-482.
(doi: 10.1038/nrneph.2017.78)
(PMID:28626222)
Shiels, Paul G. ORCID: https://orcid.org/0000-0002-7577-9843, Stenvinkel, Peter, Kooman, Jeroen P. and McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504
(2017)
Circulating markers of ageing and allostatic load: a slow train coming.
Practical Laboratory Medicine, 7,
pp. 49-54.
(doi: 10.1016/j.plabm.2016.04.002)
(PMID:28856219)
(PMCID:PMC5574864)
Stenvinkel, P. et al. (2017) CDKN2A/p16INK4a expression is associated with vascular progeria in chronic kidney disease. Aging, 9(2), pp. 494-507. (doi: 10.18632/aging.101173) (PMID:28192277)
2016
Khojah, Sohair M., Payne, Anthony P., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504 and Shields, Paul G.
(2016)
Segmental aging underlies the development of a Parkinson phenotype in the AS/AGU rat.
Cells, 5(4),
38.
(doi: 10.3390/cells5040038)
(PMID:27763519)
(PMCID:PMC5187522)
Luttropp, K. et al. (2016) Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy. Transplantation Direct, 2(12), e116. (doi: 10.1097/TXD.0000000000000629) (PMID:27990481) (PMCID:PMC5142370)
McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Anthony, Diana F., Moulisova, Vladimira
ORCID: https://orcid.org/0000-0003-0700-2837, MacDonald, Alasdair I., Macintyre, Alan, Thomson, Jacqueline, Nag, Abhijeet, Davies, R. Wayne and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2016)
Microvesicles but not exosomes from Pathfinder Cells stimulate functional recovery of the pancreas in a mouse streptozotocin-induced diabetes model.
Rejuvenation Research, 19(3),
pp. 223-232.
(doi: 10.1089/rej.2015.1723)
McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504 and McEwan, Iain J.
(2016)
Posttranslational modifications of steroid receptors: phosphorylation.
In: McEwan, Iain J. (ed.)
The Nuclear Receptor Superfamily: Methods and Protocols.
Series: Methods in molecular biology, 1443 (1443).
Springer New York, pp. 105-117.
ISBN 9781493937226
(doi: 10.1007/978-1-4939-3724-0_7)
McClelland, R. et al. (2016) Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake. Aging, 8(5), pp. 1135-1149. (doi: 10.18632/aging.100948) (PMID:27132985) (PMCID:PMC4931858)
Bulteel, Naomi, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843 and McLauchlan, John
ORCID: https://orcid.org/0000-0003-2217-9948
(2016)
Circulating micrornas as biomarkers for disease progression in chronic hepatitis C virus infection.
EASL International Liver Congress 2016, Barcelona, Spain, 13-17 Apr 2016.
McGuinness, D. et al. (2016) Identification of molecular markers of delayed graft function based on the regulation of biological ageing. PLoS ONE, 11(1), e0146378. (doi: 10.1371/journal.pone.0146378) (PMID:26734715) (PMCID:PMC4703336)
Kato, Sawako, Shiels, Paul G. ORCID: https://orcid.org/0000-0002-7577-9843, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Lindholm, Bengt, Stenvinkel, Peter, Nordfors, Louise, Qureshi, Abdul Rashid, Yuzawa, Yukio, Matsuo, Seiichi and Maruyama, Shoichi
(2016)
Telomere attrition and elongation after dialysis therapy initiation in patients with end-stage renal disease.
Blood Purification, 41(1-3),
pp. 25-33.
(doi: 10.1159/000440971)
Khojah, Sohair Mohammed, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843 and Payne, Anthony
(2016)
Differential Pattern of Global DNA Methylation at Two Time Points in Brain Regions of AS/AGU Rats Compared with AS Rats.
In: Eighth Saudi Students Conference in the UK, London, UK, 31 Jan - 01 Feb 2015,
pp. 625-631.
ISBN 9781783269143
(doi: 10.1142/9781783269150_0051)
2015
Curley, H, McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Kinsella, J., Quasim, T.
ORCID: https://orcid.org/0000-0002-9872-3623 and Shiels, P.
ORCID: https://orcid.org/0000-0002-7577-9843
(2015)
Intensive care unit outcomes based on telomere length as a biomarker of ageing: a pilot study.
British Journal of Anaesthesia, 115(6(e)),
pp. 950-962.
(doi: 10.1093/bja/aev116)
2014
Mcguinness, D.H. ORCID: https://orcid.org/0000-0003-2947-2047 and McGuinness, D.
ORCID: https://orcid.org/0000-0001-9057-3504
(2014)
m6a RNA methylation: the implications for health and disease.
Journal of Cancer Science and Clinical Oncology, 1(1),
105.
(doi: 10.15744/2394-6520.1.105)
2013
Robinson, Mark W., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Swann, Rachael
ORCID: https://orcid.org/0000-0002-3945-2253, Barclay, Stephen, Mills, Peter R., Patel, Arvind H.
ORCID: https://orcid.org/0000-0003-4600-2047, McLauchlan, John
ORCID: https://orcid.org/0000-0003-2217-9948 and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2013)
Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease.
Aging Cell, 12(6),
pp. 1141-1143.
(doi: 10.1111/acel.12125)
(PMID:23931242)
Gingell-Littlejohn, M., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, McGlynn, L.M., Kingsmore, D., Stevenson, K.S., Koppelstaetter, C., Clancy, M.J. and Shiels, P.
ORCID: https://orcid.org/0000-0002-7577-9843
(2013)
Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria.
PLoS ONE, 8(7),
e68133.
(doi: 10.1371/journal.pone.0068133)
(PMID:23861858)
(PMCID:PMC3701657)
McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504
(2013)
Fractal entropy: the return of unified theory of cancer.
International Journal of Cancer Studies and Research, 2,
p. 301.
Pathai, S. et al. (2013) Accelerated biological aging in HIV-infected individuals in South Africa: a case–control study. AIDS, 27(15), pp. 2375-2384. (doi: 10.1097/QAD.0b013e328363bf7f)
2012
McGuinness, D. et al. (2012) Socio-economic status is associated with epigenetic differences in the pSoBid cohort. International Journal of Epidemiology, 41(1), pp. 151-160. (doi: 10.1093/ije/dyr215)
Gingell-Littlejohn, Marc, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Stevenson, Karen Sara, Kingsmore, David Brian, Clancy, Marc and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2012)
CDKN2A Expression in Pre-Implantation Kidney Biopsies is the Single, Strongest Predictive Factor for Post-Transplant Renal Function at 1 Year.
In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Gingell-Littlejohn, Marc, Stevenson, Karen Sara, Kingsmore, David Brian, Clancy, Marc and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2012)
MicroRNA Regulation of Cellular Bio-age Provides a Novel Pre-Transplant
Prognostic and Predictive Assessment of Post Transplant Allograft Function.
In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
2011
McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, McGuinness, D.H.
ORCID: https://orcid.org/0000-0003-2947-2047, McCaul, J. and Shiels, P.G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2011)
Sirtuins, bioageing, and cancer.
Journal of Aging Research, 2011,
235754.
(doi: 10.4061/2011/235754)
(PMID:21766030)
(PMCID:PMC3134127)
McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Skommer, J. and Wlodkowic, D.
(2011)
Self-adhesive microculture system for extended live cell imaging.
Biotechnic and Histochemistry, 86(3),
pp. 174-180.
(doi: 10.3109/10520290903547075)
Gingell-Littlejohn, M., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, McGlynn, L. M., Kingsmore, D., Clancy, M. J., Koppelstaetter, C., Mayer, G. and Shiels, P.G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2011)
Telomere Length Impacts on Allograft Function Post Kidney Transplant.
In: 2011 American Transplant Conference, Phildadelphia, PA, USA, 30 Apr - 4 May 2011,
2010
McEwan, I.J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Hay, C.W., Millar, R.P., Saunders, P.T. and Fraser, H.M.
(2010)
Identification of androgen receptor phosphorylation in the primate ovary in vivo.
Reproduction, 140(1),
pp. 93-104.
(doi: 10.1530/REP-10-0140)
2009
Wlodkowic, D., Skommer, J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Hillier, C. and Darzynkiewicz, Z.
(2009)
ER-Golgi network - a future target for anti-cancer therapy.
Leukemia Research, 33(11),
pp. 1440-1447.
(doi: 10.1016/j.leukres.2009.05.025)
Wlodkowic, D., Skommer, J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Faley, S., Kolch, W., Darzynkiewicz, Z. and Cooper, J.M.
ORCID: https://orcid.org/0000-0002-2358-1050
(2009)
Chip-based dynamic real-time quantification of drug-induced cytotoxicity in human tumor cells.
Analytical Chemistry, 81(16),
pp. 6952-6959.
(doi: 10.1021/ac9010217)
Wlodkowic, D., Faley, S., Skommer, J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Cooper, J.M.
ORCID: https://orcid.org/0000-0002-2358-1050
(2009)
Biological implications of polymeric microdevices for live cell assays.
Analytical Chemistry, 81(23),
pp. 9828-9833.
(doi: 10.1021/ac902010s)
2008
Piestrzeniewicz-Ulanska, D., McGuinness, D.H. ORCID: https://orcid.org/0000-0003-2947-2047 and Yeaman, G.R.
(2008)
TGF-β signaling in endometrial cancer.
In: Jakowlew, S.B. (ed.)
Transforming Growth Factor-β in Cancer Therapy.
Series: Cancer Drug Discovery and Development, 2.
Humana Press: Totowa, NJ, pp. 63-78.
ISBN 9781588297150
(doi: 10.1007/978-1-59745-293-9_5)
2007
Nayyar, T., Bruner-Tran, K.L., Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Osteen, K.G.
(2007)
Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis.
Reproductive Toxicology, 23(3),
pp. 326-336.
(doi: 10.1016/j.reprotox.2006.09.007)
2005
Bruner-Tran, K.L., McGuiness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Eisenberg, E. and Osteen, K.G.
(2005)
Endometrial Expression of TGF-Beta 2 and EBAF is Disrupted in Women with Endometriosis and in Normal Endometrium Exposed to Dioxin.
In: Society for Gynecologic Investigation (SGI), Houston, TX USA, 2005,
321A.
(doi: 10.1177/107155760501200205)
2004
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M., Semczuk, A., Rechberger, T., Jakowicki, J.A. and Krajewska, W.M.
(2004)
TGF-beta signaling is disrupted in endometrioid-type endometrial carcinomas.
Gynecologic Oncology, 95(1),
pp. 173-180.
(doi: 10.1016/j.ygyno.2004.06.032)
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Bruner-Tran, K., Yeaman, G., Eisenberg, E. and Osteen, K.
(2004)
Interferon-γ induces degradation of TβR-I in the human endometrium: Implications for endometriosis.
Fertility and Sterility, 82(S2),
S69-S70.
(doi: 10.1016/j.fertnstert.2004.07.178)
2003
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M.
(2003)
Expression and intracellular localization of Smad proteins in human endometrial cancer.
Oncology Reports, 10(5),
pp. 1539-1544.
2002
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M.
(2002)
Expression of TGF-beta type I and II receptors in normal and cancerous human endometrium.
Cancer Letters, 186(2),
pp. 231-239.
(doi: 10.1016/S0304-3835(02)00351-8)
2001
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Krajewska, W.M.
(2001)
Crossing path with smads.
In: Heilmeyer, L. and Friedrisch, P. (eds.)
Protein Modules in Cellular Signalling.
Series: NATO science series. Series A, Life sciences,; v. 318; Variation: NATO science series.; Series A,; Life sciences ;; v. 318., 318.
IOS Press,US: USA, pp. 123-131.
ISBN 9781586031800
2000
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M. and Krajewska, W.M.
(2000)
The smad pathway in TGF-β signalling.
Cellular and Molecular Biology Letters, 5,
pp. 381-396.
1999
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504
(1999)
Urokinazowy układ aktywacji plazminogenu i jego znaczenie w progresji nowotworów.
Postepy Biochemii, 45,
pp. 42-50.
1998
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504
(1998)
Urokinase plasminogen activator system and its role in cancer and metastasis.
Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14,
pp. 175-190.
Blasiak, J., Smolarz, B., Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Pytel, J.
(1998)
The 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene in subject with cancer.
Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14,
pp. 167-174.
Smolarz, B., Blasiak, J., Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Pytel, J.
(1998)
Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism in subjects with cancer.
Cellular and Molecular Biology Letters, 3(1),
pp. 49-56.
Articles
Nyirenda, J. et al. (2024) Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population. Nature Medicine, (doi: 10.1038/s41591-024-03354-3) (Early Online Publication)
Abrams, S. T. et al. (2024) Damage-associated cellular markers in the clinical and pathogenic profile of vaccine-induced immune thrombotic thrombocytopenia. Journal of Thrombosis and Haemostasis, 22(4), pp. 1145-1153. (doi: 10.1016/j.jtha.2023.12.008) (PMID:38103733)
Nyirenda, J. et al. (2023) Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response. bioRxiv, (doi: 10.1101/2023.11.16.566964)
Craven, Hannah, Erlandsson, Helen, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, McGuinness, David
ORCID: https://orcid.org/0000-0003-2947-2047, Mafra, Denise, Ijaz, Umer Zeeshan
ORCID: https://orcid.org/0000-0001-5780-8551, Bergman, Peter, Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843 and Stenvinkel, Peter
(2023)
A normative microbiome is not restored following kidney transplantation.
Clinical Science, 137(20),
pp. 1563-1575.
(doi: 10.1042/CS20230779)
(PMID:37756543)
Panagiotou, Nikolaos ORCID: https://orcid.org/0000-0003-3157-3285, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Jaminon, Armand M.G., Mees, Barend, Selman, Colin
ORCID: https://orcid.org/0000-0002-8727-0593, Schurgers, Leon and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2023)
Microvesicle-mediated tissue regeneration mitigates the effects of cellular ageing.
Cells, 12(13),
1707.
(doi: 10.3390/cells12131707)
(PMID:37443741)
(PMCID:PMC10340655)
Mulvey, Lorna, Wilkie, Stephen E., Borland, Gillian, Griffiths, Kate, Sinclair, Amy, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Watson, David G. and Selman, Colin
ORCID: https://orcid.org/0000-0002-8727-0593
(2021)
Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice.
Molecular and Cellular Endocrinology, 535,
111376.
(doi: 10.1016/j.mce.2021.111376)
(PMID:34246728)
(PMCID:PMC8417819)
Craven, H. et al. (2021) Socioeconomic position links circulatory microbiota differences with biological age. Scientific Reports, 11, 12629. (doi: 10.1038/s41598-021-92042-0) (PMID:34135381) (PMCID:PMC8209159)
Moxon, C. A. et al. (2020) Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria. Blood Advances, 4(13), pp. 2851-2864. (doi: 10.1182/bloodadvances.2019001258) (PMID:32579667) (PMCID:PMC7362376)
Moxon, Christopher A. ORCID: https://orcid.org/0000-0001-6087-9393, Gibbins, Matthew P.
ORCID: https://orcid.org/0000-0002-7166-044X, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Milner, Danny A. and Marti, Matthias
ORCID: https://orcid.org/0000-0003-1040-9566
(2020)
New insights into malaria pathogenesis.
Annual Review of Pathology: Mechanisms of Disease, 15(1),
pp. 315-343.
(doi: 10.1146/annurev-pathmechdis-012419-032640)
(PMID:31648610)
de Kok, M. J. et al. (2019) The neglectable impact of delayed graft function on long-term graft survival in kidneys donated after circulatory death associates with superior organ resilience. Annals of Surgery, 270(5), pp. 877-883. (doi: 10.1097/SLA.0000000000003515) (PMID:31567503)
Diaz-Albiter, Hector M., Regnault, Clément, Alpizar-Sosa, Edubiel A., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519 and Dillon, Rod J.
(2018)
Non-invasive visualisation and identification of fluorescent.
Wellcome Open Research, 3,
160.
(doi: 10.12688/wellcomeopenres.14910.1)
(PMID:30756095)
(PMCID:PMC6367660)
McGuinness, D. et al. (2018) A molecular signature for delayed graft function. Aging Cell, 17(5), e12825. (doi: 10.1111/acel.12825) (PMID:30094915) (PMCID:PMC6156499)
Lakhdar, Ramzi, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Drost, Ellen M., Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843, Bastos, Ricardo, MacNee, William and Rabinovich, Roberto A.
(2018)
Role of accelerated ageing in limb muscle wasting of patients with COPD.
International Journal of Chronic Obstructive Pulmonary Disease, 13,
pp. 1987-1998.
(doi: 10.2147/COPD.S155952)
(PMID:29970961)
(PMCID:PMC6022820)
Shiels, Paul G. ORCID: https://orcid.org/0000-0002-7577-9843, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Eriksson, Maria, Kooman, Jeroen P. and Stenvinkel, Peter
(2017)
The role of epigenetics in renal ageing.
Nature Reviews Nephrology, 13,
pp. 471-482.
(doi: 10.1038/nrneph.2017.78)
(PMID:28626222)
Shiels, Paul G. ORCID: https://orcid.org/0000-0002-7577-9843, Stenvinkel, Peter, Kooman, Jeroen P. and McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504
(2017)
Circulating markers of ageing and allostatic load: a slow train coming.
Practical Laboratory Medicine, 7,
pp. 49-54.
(doi: 10.1016/j.plabm.2016.04.002)
(PMID:28856219)
(PMCID:PMC5574864)
Stenvinkel, P. et al. (2017) CDKN2A/p16INK4a expression is associated with vascular progeria in chronic kidney disease. Aging, 9(2), pp. 494-507. (doi: 10.18632/aging.101173) (PMID:28192277)
Khojah, Sohair M., Payne, Anthony P., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504 and Shields, Paul G.
(2016)
Segmental aging underlies the development of a Parkinson phenotype in the AS/AGU rat.
Cells, 5(4),
38.
(doi: 10.3390/cells5040038)
(PMID:27763519)
(PMCID:PMC5187522)
Luttropp, K. et al. (2016) Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy. Transplantation Direct, 2(12), e116. (doi: 10.1097/TXD.0000000000000629) (PMID:27990481) (PMCID:PMC5142370)
McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Anthony, Diana F., Moulisova, Vladimira
ORCID: https://orcid.org/0000-0003-0700-2837, MacDonald, Alasdair I., Macintyre, Alan, Thomson, Jacqueline, Nag, Abhijeet, Davies, R. Wayne and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2016)
Microvesicles but not exosomes from Pathfinder Cells stimulate functional recovery of the pancreas in a mouse streptozotocin-induced diabetes model.
Rejuvenation Research, 19(3),
pp. 223-232.
(doi: 10.1089/rej.2015.1723)
McClelland, R. et al. (2016) Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake. Aging, 8(5), pp. 1135-1149. (doi: 10.18632/aging.100948) (PMID:27132985) (PMCID:PMC4931858)
McGuinness, D. et al. (2016) Identification of molecular markers of delayed graft function based on the regulation of biological ageing. PLoS ONE, 11(1), e0146378. (doi: 10.1371/journal.pone.0146378) (PMID:26734715) (PMCID:PMC4703336)
Kato, Sawako, Shiels, Paul G. ORCID: https://orcid.org/0000-0002-7577-9843, McGuinness, Dagmara
ORCID: https://orcid.org/0000-0001-9057-3504, Lindholm, Bengt, Stenvinkel, Peter, Nordfors, Louise, Qureshi, Abdul Rashid, Yuzawa, Yukio, Matsuo, Seiichi and Maruyama, Shoichi
(2016)
Telomere attrition and elongation after dialysis therapy initiation in patients with end-stage renal disease.
Blood Purification, 41(1-3),
pp. 25-33.
(doi: 10.1159/000440971)
Curley, H, McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Kinsella, J., Quasim, T.
ORCID: https://orcid.org/0000-0002-9872-3623 and Shiels, P.
ORCID: https://orcid.org/0000-0002-7577-9843
(2015)
Intensive care unit outcomes based on telomere length as a biomarker of ageing: a pilot study.
British Journal of Anaesthesia, 115(6(e)),
pp. 950-962.
(doi: 10.1093/bja/aev116)
Mcguinness, D.H. ORCID: https://orcid.org/0000-0003-2947-2047 and McGuinness, D.
ORCID: https://orcid.org/0000-0001-9057-3504
(2014)
m6a RNA methylation: the implications for health and disease.
Journal of Cancer Science and Clinical Oncology, 1(1),
105.
(doi: 10.15744/2394-6520.1.105)
Robinson, Mark W., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Swann, Rachael
ORCID: https://orcid.org/0000-0002-3945-2253, Barclay, Stephen, Mills, Peter R., Patel, Arvind H.
ORCID: https://orcid.org/0000-0003-4600-2047, McLauchlan, John
ORCID: https://orcid.org/0000-0003-2217-9948 and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2013)
Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease.
Aging Cell, 12(6),
pp. 1141-1143.
(doi: 10.1111/acel.12125)
(PMID:23931242)
Gingell-Littlejohn, M., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, McGlynn, L.M., Kingsmore, D., Stevenson, K.S., Koppelstaetter, C., Clancy, M.J. and Shiels, P.
ORCID: https://orcid.org/0000-0002-7577-9843
(2013)
Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria.
PLoS ONE, 8(7),
e68133.
(doi: 10.1371/journal.pone.0068133)
(PMID:23861858)
(PMCID:PMC3701657)
McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504
(2013)
Fractal entropy: the return of unified theory of cancer.
International Journal of Cancer Studies and Research, 2,
p. 301.
Pathai, S. et al. (2013) Accelerated biological aging in HIV-infected individuals in South Africa: a case–control study. AIDS, 27(15), pp. 2375-2384. (doi: 10.1097/QAD.0b013e328363bf7f)
McGuinness, D. et al. (2012) Socio-economic status is associated with epigenetic differences in the pSoBid cohort. International Journal of Epidemiology, 41(1), pp. 151-160. (doi: 10.1093/ije/dyr215)
McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, McGuinness, D.H.
ORCID: https://orcid.org/0000-0003-2947-2047, McCaul, J. and Shiels, P.G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2011)
Sirtuins, bioageing, and cancer.
Journal of Aging Research, 2011,
235754.
(doi: 10.4061/2011/235754)
(PMID:21766030)
(PMCID:PMC3134127)
McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Skommer, J. and Wlodkowic, D.
(2011)
Self-adhesive microculture system for extended live cell imaging.
Biotechnic and Histochemistry, 86(3),
pp. 174-180.
(doi: 10.3109/10520290903547075)
McEwan, I.J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Hay, C.W., Millar, R.P., Saunders, P.T. and Fraser, H.M.
(2010)
Identification of androgen receptor phosphorylation in the primate ovary in vivo.
Reproduction, 140(1),
pp. 93-104.
(doi: 10.1530/REP-10-0140)
Wlodkowic, D., Skommer, J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Hillier, C. and Darzynkiewicz, Z.
(2009)
ER-Golgi network - a future target for anti-cancer therapy.
Leukemia Research, 33(11),
pp. 1440-1447.
(doi: 10.1016/j.leukres.2009.05.025)
Wlodkowic, D., Skommer, J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Faley, S., Kolch, W., Darzynkiewicz, Z. and Cooper, J.M.
ORCID: https://orcid.org/0000-0002-2358-1050
(2009)
Chip-based dynamic real-time quantification of drug-induced cytotoxicity in human tumor cells.
Analytical Chemistry, 81(16),
pp. 6952-6959.
(doi: 10.1021/ac9010217)
Wlodkowic, D., Faley, S., Skommer, J., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Cooper, J.M.
ORCID: https://orcid.org/0000-0002-2358-1050
(2009)
Biological implications of polymeric microdevices for live cell assays.
Analytical Chemistry, 81(23),
pp. 9828-9833.
(doi: 10.1021/ac902010s)
Nayyar, T., Bruner-Tran, K.L., Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Osteen, K.G.
(2007)
Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis.
Reproductive Toxicology, 23(3),
pp. 326-336.
(doi: 10.1016/j.reprotox.2006.09.007)
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M., Semczuk, A., Rechberger, T., Jakowicki, J.A. and Krajewska, W.M.
(2004)
TGF-beta signaling is disrupted in endometrioid-type endometrial carcinomas.
Gynecologic Oncology, 95(1),
pp. 173-180.
(doi: 10.1016/j.ygyno.2004.06.032)
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Bruner-Tran, K., Yeaman, G., Eisenberg, E. and Osteen, K.
(2004)
Interferon-γ induces degradation of TβR-I in the human endometrium: Implications for endometriosis.
Fertility and Sterility, 82(S2),
S69-S70.
(doi: 10.1016/j.fertnstert.2004.07.178)
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M.
(2003)
Expression and intracellular localization of Smad proteins in human endometrial cancer.
Oncology Reports, 10(5),
pp. 1539-1544.
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M.
(2002)
Expression of TGF-beta type I and II receptors in normal and cancerous human endometrium.
Cancer Letters, 186(2),
pp. 231-239.
(doi: 10.1016/S0304-3835(02)00351-8)
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504, Brys, M. and Krajewska, W.M.
(2000)
The smad pathway in TGF-β signalling.
Cellular and Molecular Biology Letters, 5,
pp. 381-396.
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504
(1999)
Urokinazowy układ aktywacji plazminogenu i jego znaczenie w progresji nowotworów.
Postepy Biochemii, 45,
pp. 42-50.
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504
(1998)
Urokinase plasminogen activator system and its role in cancer and metastasis.
Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14,
pp. 175-190.
Blasiak, J., Smolarz, B., Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Pytel, J.
(1998)
The 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene in subject with cancer.
Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14,
pp. 167-174.
Smolarz, B., Blasiak, J., Piestrzeniewicz, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Pytel, J.
(1998)
Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism in subjects with cancer.
Cellular and Molecular Biology Letters, 3(1),
pp. 49-56.
Book Sections
McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504 and McEwan, Iain J.
(2016)
Posttranslational modifications of steroid receptors: phosphorylation.
In: McEwan, Iain J. (ed.)
The Nuclear Receptor Superfamily: Methods and Protocols.
Series: Methods in molecular biology, 1443 (1443).
Springer New York, pp. 105-117.
ISBN 9781493937226
(doi: 10.1007/978-1-4939-3724-0_7)
Piestrzeniewicz-Ulanska, D., McGuinness, D.H. ORCID: https://orcid.org/0000-0003-2947-2047 and Yeaman, G.R.
(2008)
TGF-β signaling in endometrial cancer.
In: Jakowlew, S.B. (ed.)
Transforming Growth Factor-β in Cancer Therapy.
Series: Cancer Drug Discovery and Development, 2.
Humana Press: Totowa, NJ, pp. 63-78.
ISBN 9781588297150
(doi: 10.1007/978-1-59745-293-9_5)
Piestrzeniewicz-Ulanska, D. ORCID: https://orcid.org/0000-0001-9057-3504 and Krajewska, W.M.
(2001)
Crossing path with smads.
In: Heilmeyer, L. and Friedrisch, P. (eds.)
Protein Modules in Cellular Signalling.
Series: NATO science series. Series A, Life sciences,; v. 318; Variation: NATO science series.; Series A,; Life sciences ;; v. 318., 318.
IOS Press,US: USA, pp. 123-131.
ISBN 9781586031800
Conference or Workshop Item
Bulteel, Naomi, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843 and McLauchlan, John
ORCID: https://orcid.org/0000-0003-2217-9948
(2016)
Circulating micrornas as biomarkers for disease progression in chronic hepatitis C virus infection.
EASL International Liver Congress 2016, Barcelona, Spain, 13-17 Apr 2016.
Conference Proceedings
Khojah, Sohair Mohammed, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843 and Payne, Anthony
(2016)
Differential Pattern of Global DNA Methylation at Two Time Points in Brain Regions of AS/AGU Rats Compared with AS Rats.
In: Eighth Saudi Students Conference in the UK, London, UK, 31 Jan - 01 Feb 2015,
pp. 625-631.
ISBN 9781783269143
(doi: 10.1142/9781783269150_0051)
Gingell-Littlejohn, Marc, McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Stevenson, Karen Sara, Kingsmore, David Brian, Clancy, Marc and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2012)
CDKN2A Expression in Pre-Implantation Kidney Biopsies is the Single, Strongest Predictive Factor for Post-Transplant Renal Function at 1 Year.
In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Gingell-Littlejohn, Marc, Stevenson, Karen Sara, Kingsmore, David Brian, Clancy, Marc and Shiels, Paul G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2012)
MicroRNA Regulation of Cellular Bio-age Provides a Novel Pre-Transplant
Prognostic and Predictive Assessment of Post Transplant Allograft Function.
In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
Gingell-Littlejohn, M., McGuinness, D. ORCID: https://orcid.org/0000-0001-9057-3504, McGlynn, L. M., Kingsmore, D., Clancy, M. J., Koppelstaetter, C., Mayer, G. and Shiels, P.G.
ORCID: https://orcid.org/0000-0002-7577-9843
(2011)
Telomere Length Impacts on Allograft Function Post Kidney Transplant.
In: 2011 American Transplant Conference, Phildadelphia, PA, USA, 30 Apr - 4 May 2011,
Bruner-Tran, K.L., McGuiness, D. ORCID: https://orcid.org/0000-0001-9057-3504, Eisenberg, E. and Osteen, K.G.
(2005)
Endometrial Expression of TGF-Beta 2 and EBAF is Disrupted in Women with Endometriosis and in Normal Endometrium Exposed to Dioxin.
In: Society for Gynecologic Investigation (SGI), Houston, TX USA, 2005,
321A.
(doi: 10.1177/107155760501200205)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Sepsis treatment by targeting antibiotic released bacterial proteins (STTAR-BacPro)
Medical Research Council
2024 - 2024