Dr Calum Bain

  • Reader (Immunology & Infection)

email: Calum.Bain@glasgow.ac.uk

Sir Graeme Davies Building, 126 University Place, Glasgow, G12 8TA

Import to contacts

Biography

Calum is an immunologist with an interest in the fundamental biology of innate immune cells, particularly monocytes and macrophages. These cells are crucial for normal development, tissue health and protective immunity, but they also become dysregulated and disease-promoting in chronic inflammatory and fibrotic diseases. Calum’s lab focusses on understanding how essential peacekeeper cells can become power aggressors in the context of disease.

Publications

List by: Type | Date

Jump to: 2021 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012
Number of items: 22.

2021

Wright, P. B. et al. (2021) The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease. Scientific Reports, 11, 19616. (doi: 10.1038/s41598-021-98611-7) (PMID:34608184) (PMCID:PMC8490356)

Mowat, Allan M. and Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X (2021) Guardians of the epithelium: macrophages protect against toxic fungal derivatives. Mucosal Immunology, 14(3), pp. 542-543. (doi: 10.1038/s41385-020-00369-0) (PMID:33495494) (PMCID:PMC8076022)

2018

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Oliphant, Christopher J., Thomson, Carolyn A., Kullberg, Marika C. and Mowat, Allan Mcl. (2018) Pro-inflammatory role of monocyte-derived CX3CR1int macrophages in Helicobacter hepaticus-induced colitis. Infection and Immunity, 86(2), e00579-17. (doi: 10.1128/IAI.00579-17) (PMID:29203542) (PMCID:PMC5778360)

2017

Mowat, Allan McI, Scott, Charlotte L. and Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X (2017) Barrier-tissue macrophages: functional adaptation to environmental challenges. Nature Medicine, 23(11), pp. 1258-1270. (doi: 10.1038/nm.4430) (PMID:29117177)

Bain, C.C. et al. (2017) TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine. Nature Communications, 8, 620. (doi: 10.1038/s41467-017-00658-6) (PMID:28931816) (PMCID:PMC5607002)

Mowat, Allan McI and Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X (2017) Alternative monocytes settle in for the long term. Nature Immunology, 18(6), pp. 599-600. (doi: 10.1038/ni.3749) (PMID:28518159)

Scott, Charlotte L., Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, Allan McI (2017) Isolation and identification of intestinal myeloid cells. In: Clausen, Björn E. and Laman, Jon D. (eds.) Inflammation: Methods and Protocols. Series: Methods in molecular biology (1559). Humana Press, pp. 223-239. ISBN 9781493967841 (doi: 10.1007/978-1-4939-6786-5_15)

Schridde, A. et al. (2017) Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling. Mucosal Immunology, 10, pp. 1387-1399. (doi: 10.1038/mi.2016.142) (PMID:28145440) (PMCID:PMC5417360)

2016

Drummond, R.A., Dambuza, I.M., Vautier, S., Taylor, J.A., Reid, D.M., Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Underhill, D.M., Masopust, D., Kaplan, D.H. and Brown, G.D. (2016) CD4+ T-cell survival in the GI tract requires dectin-1 during fungal infection. Mucosal Immunology, 9(2), pp. 492-502. (doi: 10.1038/mi.2015.79) (PMID:26349660) (PMCID:PMC4677461)

2015

Stutchfield, B. M. et al. (2015) CSF1 restores innate immunity after liver injury in mice and serum levels indicate outcomes of patients with acute liver failure. Gastroenterology, 149(7), 1896-1909.e14. (doi: 10.1053/j.gastro.2015.08.053) (PMID:26344055) (PMCID:PMC4672154)

2014

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Bravo-Blas, Alberto, Scott, Charlotte L., Gomez Perdiguero, Elisa, Geissmann, Frederic, Henri, Sandrine, Malissen, Bernard, Osborne, Lisa C., Artis, David and Mowat, Allan McI (2014) Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nature Immunology, 15(10), pp. 929-937. (doi: 10.1038/ni.2967)

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, Allan McI (2014) The monocyte-macrophage axis in the intestine. Cellular Immunology, 291(1-2), pp. 41-48. (doi: 10.1016/j.cellimm.2014.03.012)

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, Allan McI. (2014) Macrophages in intestinal homeostasis and inflammation. Immunological Reviews, 260(1), pp. 102-117. (doi: 10.1111/imr.12192)

Cerovic, Vuk, Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Mowat, Allan M. and Milling, Simon W.F. ORCID logoORCID: https://orcid.org/0000-0003-4384-5516 (2014) Intestinal macrophages and dendritic cells: what's the difference? Trends in Immunology, 35(6), pp. 270-277. (doi: 10.1016/j.it.2014.04.003)

Mirchandani, Ananda S., Besnard, Anne-Gaelle, Yip, Edwin, Scott, C., Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Cerovic, Vuk, Salmond, Robert J. and Liew, Foo J. (2014) Type 2 innate lymphoid cells drive CD4+ Th2 cell responses. Journal of Immunology, 192(5), pp. 2442-2448. (doi: 10.4049/jimmunol.1300974)

Cerovic, V. et al. (2014) Lymph borne CD8α+ DCs are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells. Mucosal Immunology, 8(1), pp. 38-48. (doi: 10.1038/mi.2014.40)

Mattei, F. et al. (2014) The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS ONE, 9(8), e105429. (doi: 10.1371/journal.pone.0105429) (PMID:25137049) (PMCID:PMC4138162)

Scott, C.L. et al. (2014) CCR2+CD103− intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells. Mucosal Immunology, 8(2), pp. 327-339. (doi: 10.1038/mi.2014.70)

2013

Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Scott, C.L., Uronen-Hansson, H., Gudjonsson, S., Jansson, O., Grip, O., Guilliams, M., Malissen, B., Agace, W.W. and Mowat, A.M. (2013) Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors. Mucosal Immunology, 6(3), pp. 498-510. (doi: 10.1038/mi.2012.89) (PMID:22990622) (PMCID:PMC3629381)

2012

Tamoutounour, S. et al. (2012) CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. European Journal of Immunology, 42(12), pp. 3150-3166. (doi: 10.1002/eji.201242847)

Salmond, R.J., Mirchandani, A.S., Besnard, A.-G., Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Thomson, N.C. and Liew, F.Y. (2012) IL-33 induces innate lymphoid cell–mediated airway inflammation by activating mammalian target of rapamycin. Journal of Allergy and Clinical Immunology, 130(5), pp. 1159-1166. (doi: 10.1016/j.jaci.2012.05.018)

Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, A.M. (2012) CD200 receptor and macrophage function in the intestine. Immunobiology, 217(6), pp. 643-651. (doi: 10.1016/j.imbio.2011.11.004)

This list was generated on Mon Nov 3 02:11:10 2025 GMT.
Jump to: Articles | Book Sections
Number of items: 22.

Articles

Wright, P. B. et al. (2021) The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease. Scientific Reports, 11, 19616. (doi: 10.1038/s41598-021-98611-7) (PMID:34608184) (PMCID:PMC8490356)

Mowat, Allan M. and Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X (2021) Guardians of the epithelium: macrophages protect against toxic fungal derivatives. Mucosal Immunology, 14(3), pp. 542-543. (doi: 10.1038/s41385-020-00369-0) (PMID:33495494) (PMCID:PMC8076022)

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Oliphant, Christopher J., Thomson, Carolyn A., Kullberg, Marika C. and Mowat, Allan Mcl. (2018) Pro-inflammatory role of monocyte-derived CX3CR1int macrophages in Helicobacter hepaticus-induced colitis. Infection and Immunity, 86(2), e00579-17. (doi: 10.1128/IAI.00579-17) (PMID:29203542) (PMCID:PMC5778360)

Mowat, Allan McI, Scott, Charlotte L. and Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X (2017) Barrier-tissue macrophages: functional adaptation to environmental challenges. Nature Medicine, 23(11), pp. 1258-1270. (doi: 10.1038/nm.4430) (PMID:29117177)

Bain, C.C. et al. (2017) TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine. Nature Communications, 8, 620. (doi: 10.1038/s41467-017-00658-6) (PMID:28931816) (PMCID:PMC5607002)

Mowat, Allan McI and Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X (2017) Alternative monocytes settle in for the long term. Nature Immunology, 18(6), pp. 599-600. (doi: 10.1038/ni.3749) (PMID:28518159)

Schridde, A. et al. (2017) Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling. Mucosal Immunology, 10, pp. 1387-1399. (doi: 10.1038/mi.2016.142) (PMID:28145440) (PMCID:PMC5417360)

Drummond, R.A., Dambuza, I.M., Vautier, S., Taylor, J.A., Reid, D.M., Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Underhill, D.M., Masopust, D., Kaplan, D.H. and Brown, G.D. (2016) CD4+ T-cell survival in the GI tract requires dectin-1 during fungal infection. Mucosal Immunology, 9(2), pp. 492-502. (doi: 10.1038/mi.2015.79) (PMID:26349660) (PMCID:PMC4677461)

Stutchfield, B. M. et al. (2015) CSF1 restores innate immunity after liver injury in mice and serum levels indicate outcomes of patients with acute liver failure. Gastroenterology, 149(7), 1896-1909.e14. (doi: 10.1053/j.gastro.2015.08.053) (PMID:26344055) (PMCID:PMC4672154)

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Bravo-Blas, Alberto, Scott, Charlotte L., Gomez Perdiguero, Elisa, Geissmann, Frederic, Henri, Sandrine, Malissen, Bernard, Osborne, Lisa C., Artis, David and Mowat, Allan McI (2014) Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nature Immunology, 15(10), pp. 929-937. (doi: 10.1038/ni.2967)

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, Allan McI (2014) The monocyte-macrophage axis in the intestine. Cellular Immunology, 291(1-2), pp. 41-48. (doi: 10.1016/j.cellimm.2014.03.012)

Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, Allan McI. (2014) Macrophages in intestinal homeostasis and inflammation. Immunological Reviews, 260(1), pp. 102-117. (doi: 10.1111/imr.12192)

Cerovic, Vuk, Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Mowat, Allan M. and Milling, Simon W.F. ORCID logoORCID: https://orcid.org/0000-0003-4384-5516 (2014) Intestinal macrophages and dendritic cells: what's the difference? Trends in Immunology, 35(6), pp. 270-277. (doi: 10.1016/j.it.2014.04.003)

Mirchandani, Ananda S., Besnard, Anne-Gaelle, Yip, Edwin, Scott, C., Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Cerovic, Vuk, Salmond, Robert J. and Liew, Foo J. (2014) Type 2 innate lymphoid cells drive CD4+ Th2 cell responses. Journal of Immunology, 192(5), pp. 2442-2448. (doi: 10.4049/jimmunol.1300974)

Cerovic, V. et al. (2014) Lymph borne CD8α+ DCs are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells. Mucosal Immunology, 8(1), pp. 38-48. (doi: 10.1038/mi.2014.40)

Mattei, F. et al. (2014) The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS ONE, 9(8), e105429. (doi: 10.1371/journal.pone.0105429) (PMID:25137049) (PMCID:PMC4138162)

Scott, C.L. et al. (2014) CCR2+CD103− intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells. Mucosal Immunology, 8(2), pp. 327-339. (doi: 10.1038/mi.2014.70)

Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Scott, C.L., Uronen-Hansson, H., Gudjonsson, S., Jansson, O., Grip, O., Guilliams, M., Malissen, B., Agace, W.W. and Mowat, A.M. (2013) Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors. Mucosal Immunology, 6(3), pp. 498-510. (doi: 10.1038/mi.2012.89) (PMID:22990622) (PMCID:PMC3629381)

Tamoutounour, S. et al. (2012) CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. European Journal of Immunology, 42(12), pp. 3150-3166. (doi: 10.1002/eji.201242847)

Salmond, R.J., Mirchandani, A.S., Besnard, A.-G., Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X, Thomson, N.C. and Liew, F.Y. (2012) IL-33 induces innate lymphoid cell–mediated airway inflammation by activating mammalian target of rapamycin. Journal of Allergy and Clinical Immunology, 130(5), pp. 1159-1166. (doi: 10.1016/j.jaci.2012.05.018)

Bain, C.C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, A.M. (2012) CD200 receptor and macrophage function in the intestine. Immunobiology, 217(6), pp. 643-651. (doi: 10.1016/j.imbio.2011.11.004)

Book Sections

Scott, Charlotte L., Bain, Calum C. ORCID logoORCID: https://orcid.org/0000-0001-8884-327X and Mowat, Allan McI (2017) Isolation and identification of intestinal myeloid cells. In: Clausen, Björn E. and Laman, Jon D. (eds.) Inflammation: Methods and Protocols. Series: Methods in molecular biology (1559). Humana Press, pp. 223-239. ISBN 9781493967841 (doi: 10.1007/978-1-4939-6786-5_15)

This list was generated on Mon Nov 3 02:11:10 2025 GMT.

A head and shoulders portrait shot of Calum Bain

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