Professor Alfredo Castello

Professor in Systems Virology (Virology)

telephone: 01413304028
email: Alfredo.Castello@glasgow.ac.uk

MRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, 464 Bearsden Road, Glasgow, G61 1QH

Import to contacts

https://orcid.org/0000-0002-1499-4662

Publications

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Jump to: 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2009 | 2008 | 2007 | 2006

Number of items: 68.

2025

Reuter, M. et al. (2025) The PAZ domain of Aedes aegypti Dicer 2 is critical for accurate and high-fidelity size determination of virus-derived small interfering RNAs. RNA, 31(5), pp. 679-691. (doi: 10.1261/rna.080149.124) (PMID:39947927) (PMCID:PMC12001973)

Chen, Honglin, Charles, Philip D., Gu, Quan ORCID: https://orcid.org/0000-0002-1201-6734, Liberatori, Sabrina, Robertson, David L. ORCID: https://orcid.org/0000-0001-6338-0221, Palmarini, Massimo ORCID: https://orcid.org/0000-0001-7007-4070, Wilson, Sam J. ORCID: https://orcid.org/0000-0002-6065-0895, Mohammed, Shabaz and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2025) Omics analyses uncover host networks defining virus-permissive and -hostile cellular states. Molecular and Cellular Proteomics, (doi: 10.1016/j.mcpro.2025.100966) (In Press)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Kamel, Wael ORCID: https://orcid.org/0000-0002-7625-2648 (2025) Nuclear RNA-binding proteins meet cytoplasmic viruses. RNA, 31(3), pp. 444-451. (doi: 10.1261/rna.080313.124) (PMID:39805659) (PMCID:PMC11874974)

2024

Kamel, W. et al. (2024) Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles. Molecular Cell, 84(24), 4896-4911.e7. (doi: 10.1016/j.molcel.2024.11.015) (PMID:39642884)

Ruscica, V. et al. (2024) XRN1 supplies free nucleotides to feed alphavirus replication. bioRxiv, (doi: 10.1101/2024.12.09.625895)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Alvarez, Lucia, Kamel, Wael ORCID: https://orcid.org/0000-0002-7625-2648, Iselin, Louisa and Hennig, Janosch (2024) Exploring the expanding universe of host-virus interactions mediated by viral RNA. Molecular Cell, 84(19), pp. 3706-3721. (doi: 10.1016/j.molcel.2024.08.027)

Álvarez, L. et al. (2024) The molecular dissection of TRIM25‘s RNA-binding mechanism provides key insights into its antiviral activity. Nature Communications, 15, 8485. (doi: 10.1038/s41467-024-52918-x) (PMID:39353916)

Xu, H. et al. (2024) Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome. Nature Methods, (doi: 10.1038/s41592-024-02439-8) (PMID:39349603) (Early Online Publication)

Kitano, Eduardo S., Nisbet, Gareth, Demyanenko, Yana, Kowalczyk, Katarzyna M., Iselin, Louisa, Cross, Stephen, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Mohammed, Shabaz (2024) Repurposed 3D printer allows economical and programmable fraction collection for proteomics of nanogram scale samples. Analytical Chemistry, 96(28), pp. 11439-11447. (doi: 10.1021/acs.analchem.4c01731) (PMID:38968027) (PMCID:PMC11256012)

2023

Rainey, Stephanie M. ORCID: https://orcid.org/0000-0001-9504-5495, Geoghegan, Vincent, Lefteri, Daniella A. ORCID: https://orcid.org/0000-0002-9985-4254, Ant, Thomas H., Martinez, Julien ORCID: https://orcid.org/0000-0001-8210-2921, McNamara, Cameron J., Kamel, Wael ORCID: https://orcid.org/0000-0002-7625-2648, de Laurent, Zaydah Rolande, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Sinkins, Steven P. ORCID: https://orcid.org/0000-0002-2678-1832 (2023) Differences in proteome perturbations caused by the Wolbachia strain wAu suggest multiple mechanisms of Wolbachia-mediated antiviral activity. Scientific Reports, 13, 11737. (doi: 10.1038/s41598-023-38127-4) (PMID:37474590) (PMCID:PMC10359319)

2022

Mestre-Farràs, N. et al. (2022) Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis. Nucleic Acids Research, 50(14), pp. 8207-8225. (doi: 10.1093/nar/gkac605) (PMID:35848924) (PMCID:PMC9371929)

Birot, Adrien, Kus, Krzysztof, Priest, Emily, Al Alwash, Ahmad, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Mohammed, Shabaz, Vasiljeva, Lidia and Kilchert, Cornelia (2022) RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response. Life Science Alliance, 5(2), e202101111. (doi: 10.26508/lsa.202101111) (PMID:34848435) (PMCID:PMC8645331)

Lee, J. Y. et al. (2022) Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences. eLife, 11, e74153. (doi: 10.7554/eLife.74153) (PMID:35049501) (PMCID:PMC8776252)

Iselin, Louisa, Palmalux, Natasha, Kamel, Wael ORCID: https://orcid.org/0000-0002-7625-2648, Simmonds, Peter, Mohammed, Shabaz and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2022) Uncovering viral RNA-host cell interactions on a proteome-wide scale. Trends in Biochemical Sciences, 47(1), pp. 23-38. (doi: 10.1016/j.tibs.2021.08.002) (PMID:34509361)

2021

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622) (PMCID:PMC7612834)

Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)

Kamel, W. et al. (2021) Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection. Molecular Cell, 81(13), 2851-2867.e7. (doi: 10.1016/j.molcel.2021.05.023) (PMID:34118193) (PMCID:PMC8142890)

Wing, P. A.C. et al. (2021) Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells. Cell Reports, 35(3), 109020. (doi: 10.1016/j.celrep.2021.109020) (PMID:33852916) (PMCID:PMC8020087)

Perez-Perri, Joel I., Noerenberg, Marko ORCID: https://orcid.org/0000-0002-4834-8888, Kamel, Wael, Lenz, Caroline E., Mohammed, Shabaz, Hentze, Matthias W. and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2021) Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture. Nature Protocols, 16, pp. 27-60. (doi: 10.1038/s41596-020-00404-1) (PMID:33208978) (PMCID:PMC7116560)

2020

Truman, Catherine Toni-Sue, Järvelin, Aino, Davis, Ilan ORCID: https://orcid.org/0000-0002-5385-3053 and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2020) HIV rev-isited. Open Biology, 10(12), 200320. (doi: 10.1098/rsob.200320) (PMID:33352061) (PMCID:PMC7776567)

Kilchert, Cornelia, Kecman, Tea, Priest, Emily, Hester, Svenja, Aydin, Ebru, Kus, Krzysztof, Rossbach, Oliver, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Mohammad, Shabaz and Vasiljeva, Lidia (2020) System-wide analyses of the fission yeast poly(A)+ RNA interactome reveal insights into organization and function of RNA–protein complexes. Genome Research, 30(7), pp. 1012-1026. (doi: 10.1101/gr.257006.119) (PMID:32554781)

Bach-Pages, Marcel, Homma, Felix, Kourelis, Jiorgos, Kaschani, Farnusch, Mohammed, Shabaz, Kaiser, Markus, van der Hoorn, Renier A.L., Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Preston, Gail M. (2020) Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture method. Biomolecules, 10(4), 661. (doi: 10.3390/biom10040661) (PMID:32344669) (PMCID:PMC7226388)

2019

Garcia-Moreno, M. et al. (2019) System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection. Molecular Cell, 74(1), pp. 196-211. (doi: 10.1016/j.molcel.2019.01.017) (PMID:30799147) (PMCID:PMC6458987)

Horos, R. et al. (2019) The small non-coding vault RNA1-1 acts as a riboregulator of autophagy. Cell, 176(5), 1054-1067.e12. (doi: 10.1016/j.cell.2019.01.030) (PMID:30773316)

2018

Avolio, R. et al. (2018) Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Research, 46(22), pp. 12067-12086. (doi: 10.1093/nar/gky873) (PMID:30260431) (PMCID:PMC6294507)

Garcia-Moreno, Manuel, Järvelin, Aino I. and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2018) Unconventional RNA-binding proteins step into the virus-host battlefront. Wiley Interdisciplinary Reviews: RNA, 9(6), e1498. (doi: 10.1002/wrna.1498) (PMID:30091184) (PMCID:PMC7169762)

Hentze, Matthias W., Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Schwarzl, Thomas and Preiss, Thomas (2018) A brave new world of RNA-binding proteins. Nature Reviews Molecular Cell Biology, 19(5), pp. 327-341. (doi: 10.1038/nrm.2017.130) (PMID:29339797)

Hobor, Fruzsina, Dallmann, Andre, Ball, Neil J., Cicchini, Carla, Battistelli, Cecilia, Ogrodowicz, Roksana W., Christodoulou, Evangelos, Martin, Stephen R. and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2018) A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nature Communications, 9, 831. (doi: 10.1038/s41467-018-03182-3) (PMID:29483512) (PMCID:PMC5827114)

Moore, Samantha, Järvelin, Aino I., Davis, Ilan, Bond, Gareth L. and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2018) Expanding horizons: new roles for non-canonical RNA-binding proteins in cancer. Current Opinion in Genetics and Development, 48, pp. 112-120. (doi: 10.1016/j.gde.2017.11.006) (PMID:29216518) (PMCID:PMC5894799)

2017

Pintacuda, G. et al. (2017) hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish polycomb-mediated chromosomal silencing. Molecular Cell, 68(5), 955-969.e10. (doi: 10.1016/j.molcel.2017.11.013) (PMID:29220657) (PMCID:PMC5735038)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Frese, Christian K., Fischer, Bernd, Järvelin, Aino I, Horos, Rastislav, Alleaume, Anne-Marie, Foehr, Sophia, Curk, Tomaz, Krijgsveld, Jeroen and Hentze, Matthias W (2017) Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap. Nature Protocols, 12(12), pp. 2447-2464. (doi: 10.1038/nprot.2017.106) (PMID:29095441)

Quintas, Ana, Pérez-Núñez, Daniel, Sánchez, Elena G., Nogal, Maria L., Hentze, Matthias W., Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Revilla, Yolanda (2017) Characterization of the African swine fever virus decapping enzyme during infection. Journal of Virology, 91(24), e00990-17. (doi: 10.1128/JVI.00990-17) (PMID:29021398) (PMCID:PMC5709586)

Choudhury, N. R. et al. (2017) RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. BMC Biology, 15, (doi: 10.1186/s12915-017-0444-9) (PMID:29117863) (PMCID:PMC5678581)

Rogell, Birgit, Fischer, Bernd, Rettel, Mandy, Krijgsveld, Jeroen, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Hentze, Matthias W. (2017) Specific RNP capture with antisense LNA/DNA mixmers. RNA, 23(8), pp. 1290-1302. (doi: 10.1261/rna.060798.117) (PMID:28476952) (PMCID:PMC5513073)

Bach-Pages, Marcel, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Preston, Gail M. (2017) Plant RNA interactome capture: revealing the plant RBPome. Trends in Plant Science, 22(6), pp. 449-451. (doi: 10.1016/j.tplants.2017.04.006) (PMID:28478905)

2016

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Fischer, Bernd, Frese, Christian K., Horos, Rastislav, Alleaume, Anne-Marie, Foehr, Sophia, Curk, Tomaz, Krijgsveld, Jeroen and Hentze, Matthias W. (2016) Comprehensive identification of RNA-binding domains in human cells. Molecular Cell, 63(4), pp. 696-710. (doi: 10.1016/j.molcel.2016.06.029) (PMID:27453046) (PMCID:PMC5003815)

Liao, Y. et al. (2016) The cardiomyocyte RNA-binding proteome: links to intermediary metabolism and heart disease. Cell Reports, 16(5), pp. 1456-1469. (doi: 10.1016/j.celrep.2016.06.084) (PMID:27452465) (PMCID:PMC4977271)

Liepelt, A. et al. (2016) Identification of RNA-binding proteins in macrophages by interactome capture. Molecular and Cellular Proteomics, 15(8), pp. 2699-2714. (doi: 10.1074/mcp.M115.056564) (PMID:27281784) (PMCID:PMC4974345)

Sysoev, Vasiliy O., Fischer, Bernd, Frese, Christian K., Gupta, Ishaan, Krijgsveld, Jeroen, Hentze, Matthias W., Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Ephrussi, Anne (2016) Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila. Nature Communications, 7, 12128. (doi: 10.1038/ncomms12128) (PMID:27378189) (PMCID:PMC4935972)

Beckmann, Benedikt M., Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Medenbach, Jan (2016) The expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactions. Pflügers Archiv European Journal of Physiology, 468(6), pp. 1029-1040. (doi: 10.1007/s00424-016-1819-4) (PMID:27165283) (PMCID:PMC4893068)

Järvelin, Aino I., Noerenberg, Marko, Davis, Ilan and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2016) The new (dis)order in RNA regulation. Cell Communication and Signaling, 14, 9. (doi: 10.1186/s12964-016-0132-3) (PMID:27048167) (PMCID:PMC4822317)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Horos, Rastislav, Strein, Claudia, Fischer, Bernd, Eichelbaum, Katrin, Steinmetz, Lars M., Krijgsveld, Jeroen and Hentze, Matthias W. (2016) Comprehensive identification of RNA-binding proteins by RNA interactome capture. In: Dassi, Erik (ed.) Post-Transcriptional Gene Regulation. Series: Methods in molecular biology (1358). Humana Press: New York, NY, pp. 131-139. ISBN 9781493930661 (doi: 10.1007/978-1-4939-3067-8_8)

2015

Beckmann, B. M. et al. (2015) The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs. Nature Communications, 6, 10127. (doi: 10.1038/ncomms10127) (PMID:26632259) (PMCID:PMC4686815)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Hentze, Matthias W. and Preiss, Thomas (2015) Metabolic enzymes enjoying new partnerships as RNA-binding proteins. Trends in Endocrinology and Metabolism, 26(12), pp. 746-757. (doi: 10.1016/j.tem.2015.09.012) (PMID:26520658) (PMCID:PMC4671484)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2015) The emerging universe of RNA-binding proteins. Biochemist, 37(2), pp. 33-38. (doi: 10.1042/BIO03702033)

2014

Strein, Claudia, Alleaume, Anne-Marie, Rothbauer, Ulrich, Hentz, Matthias W. and Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2014) A versatile assay for RNA-binding proteins in living cells. RNA, 20(5), pp. 721-731. (doi: 10.1261/rna.043562.113) (PMID:24664470) (PMCID:PMC3988573)

2013

Álvarez, Enrique, Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Carrasco, Luis and Izquierdo, José M. (2013) Poliovirus 2A protease triggers a selective nucleo-cytoplasmic redistribution of splicing factors to regulate alternative pre-mRNA splicing. PLoS ONE, 8(9), e73723. (doi: 10.1371/journal.pone.0073723) (PMID:24066065) (PMCID:PMC3774746)

Kwon, S. Chul, Yi, Hyerim, Eichelbaum, Katrin, Föhr, Sophia, Fischer, Bernd, You, Kwon Tae, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Krijgsveld, Jeroen, Hentze, Matthias W. and Kim, V. Narry (2013) The RNA-binding protein repertoire of embryonic stem cells. Nature Structural and Molecular Biology, 20(9), pp. 1122-1130. (doi: 10.1038/nsmb.2638) (PMID:23912277)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Fischer, Bernd, Hentze, Matthias W. and Preiss, Thomas (2013) RNA-binding proteins in Mendelian disease. Trends in Genetics, 29(5), pp. 318-327. (doi: 10.1016/j.tig.2013.01.004) (PMID:23415593)

Sánchez, Elena G., Quintas, Ana, Nogal, Marisa, Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Revilla, Yolanda (2013) African swine fever virus controls the host transcription and cellular machinery of protein synthesis. Virus Research, 173(1), pp. 58-75. (doi: 10.1016/j.virusres.2012.10.025) (PMID:23154157)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Horos, Rastislav, Strein, Claudia, Fischer, Bernd, Eichelbaum, Katrin, Steinmetz, Lars M., Krijgsveld, Jeroen and Hentze, Matthias W. (2013) System-wide identification of RNA-binding proteins by interactome capture. Nature Protocols, 8(3), pp. 491-500. (doi: 10.1038/nprot.2013.020) (PMID:23411631)

2012

del Pino, Javier, Jiménez, José Luis, Ventoso, Iván, Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Muñoz-Fernández, Ma. Ángeles, de Haro, César and Berlanga, Juan José (2012) GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection. PLoS ONE, 7(10), e47272. (doi: 10.1371/journal.pone.0047272) (PMID:23110064) (PMCID:PMC3479103)

Castello, A. et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell, 149(6), pp. 1393-1406. (doi: 10.1016/j.cell.2012.04.031) (PMID:22658674)

Buzon, M. J. et al. (2012) A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors. Journal of Antimicrobial Chemotherapy, 67(1), pp. 32-38. (doi: 10.1093/jac/dkr433) (PMID:21994909)

2011

Álvarez, Enrique, Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Carrasco, Luis and Izquierdo, José M. (2011) Alternative splicing, a new target to block cellular gene expression by poliovirus 2A protease. Biochemical and Biophysical Research Communications, 414(1), pp. 142-147. (doi: 10.1016/j.bbrc.2011.09.040) (PMID:21945619)

Yángüez, Emilio, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Welnowska, Ewelina, Carrasco, Luis, Goodfellow, Ian and Nieto, Amelia (2011) Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation. Virology, 413(1), pp. 93-102. (doi: 10.1016/j.virol.2011.02.012) (PMID:21377182)

Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Álvarez, Enrique and Carrasco, Luis (2011) The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases. Journal of Biomedicine and Biotechnology, 2011, 369648. (doi: 10.1155/2011/369648) (PMID:21541224) (PMCID:PMC3085340)

2009

Welnowska, Ewelina, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Moral, Pablo and Carrascó, Luis (2009) Translation of mRNAs from Vesicular Stomatitis Virus and Vaccinia Virus Is Differentially Blocked in Cells with Depletion of eIF4GI and/or eIF4GII. Journal of Molecular Biology, 394(3), pp. 506-521. (doi: 10.1016/j.jmb.2009.09.036) (PMID:19769989)

Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Franco, David, Moral-López, Pablo, Berlanga, Juan J., Álvarez, Enrique, Wimmer, Eckard and Carrasco, Luis (2009) HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage. PLoS ONE, 4(11), e7997. (doi: 10.1371/journal.pone.0007997) (PMID:19956697) (PMCID:PMC2776998)

Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Izquierdo, José M., Welnowska, Ewelina and Carrasco, Luis (2009) RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with nucleoporin cleavage. Journal of Cell Science, 122(20), pp. 3799-3809. (doi: 10.1242/jcs.055988) (PMID:19789179)

Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Quintas, Ana, Sánchez, Elena G., Sabina, Prado, Nogal, Marisa, Carrasco, Luis and Revilla, Yolanda (2009) Regulation of host translational machinery by African swine fever virus. PLoS Pathogens, 5(8), e1000562. (doi: 10.1371/journal.ppat.1000562) (PMID:19714237) (PMCID:PMC2727446)

Sanz, Miguel Ángel, Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Ventoso, Iván, Berlanga, Juan José and Carrasco, Luis (2009) Dual mechanism for the translation of subgenomic mRNA from Sindbis virus in infected and uninfected cells. PLoS ONE, 4(3), e4772. (doi: 10.1371/journal.pone.0004772) (PMID:19274090) (PMCID:PMC2651626)

2008

Madan, Vanessa, Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Carrasco, Luis (2008) Viroporins from RNA viruses induce caspase-dependent apoptosis. Cellular Microbiology, 10(2), pp. 437-451. (doi: 10.1111/j.1462-5822.2007.01057.x) (PMID:17961183) (PMCID:PMC7162385)

2007

Molina, Susana, Sanz, Miguel A., Madan, Vanesa, Ventoso, Ivan, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Carrasco, Luis (2007) Differential inhibition of cellular and Sindbis virus translation by brefeldin A. Virology, 363(2), pp. 430-436. (doi: 10.1016/j.virol.2007.02.001) (PMID:17360015)

Sanz, Miguel A., Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 and Carrasco, Luis (2007) Viral translation is coupled to transcription in Sindbis virus-infected cells. Journal of Virology, 81(13), pp. 7061-7068. (doi: 10.1128/JVI.02529-06) (PMID:17442713) (PMCID:PMC1933293)

2006

Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Alvarez, Enrique and Carrasco, Luis (2006) Differential cleavage of eIF4GI and eIF4GII in mammalian cells: effects on translation. Journal of Biological Chemistry, 281(44), pp. 33206-33216. (doi: 10.1074/jbc.m604340200) (PMID:16959778)

Álvarez, Enrique, Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Menéndez-Arias, Luis and Carrasco, Luis (2006) HIV protease cleaves poly(A)-binding protein. Biochemical Journal, 396(2), pp. 219-226. (doi: 10.1042/BJ20060108) (PMID:16594896) (PMCID:PMC1462710)

Castelló, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Sanz, Miguel Ángel, Molina, Susana and Carrasco, Luis (2006) Translation of Sindbis virus 26S mRNA does not require intact eukariotic initiation factor 4G. Journal of Molecular Biology, 355(5), pp. 942-956. (doi: 10.1016/j.jmb.2005.11.024) (PMID:16343528)

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Number of items: 68.

Articles

Ruscica, V. et al. (2024) XRN1 supplies free nucleotides to feed alphavirus replication. bioRxiv, (doi: 10.1101/2024.12.09.625895)

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622) (PMCID:PMC7612834)

Horos, R. et al. (2019) The small non-coding vault RNA1-1 acts as a riboregulator of autophagy. Cell, 176(5), 1054-1067.e12. (doi: 10.1016/j.cell.2019.01.030) (PMID:30773316)

Beckmann, B. M. et al. (2015) The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs. Nature Communications, 6, 10127. (doi: 10.1038/ncomms10127) (PMID:26632259) (PMCID:PMC4686815)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662 (2015) The emerging universe of RNA-binding proteins. Biochemist, 37(2), pp. 33-38. (doi: 10.1042/BIO03702033)

Castello, Alfredo ORCID: https://orcid.org/0000-0002-1499-4662, Horos, Rastislav, Strein, Claudia, Fischer, Bernd, Eichelbaum, Katrin, Steinmetz, Lars M., Krijgsveld, Jeroen and Hentze, Matthias W. (2013) System-wide identification of RNA-binding proteins by interactome capture. Nature Protocols, 8(3), pp. 491-500. (doi: 10.1038/nprot.2013.020) (PMID:23411631)

Castello, A. et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell, 149(6), pp. 1393-1406. (doi: 10.1016/j.cell.2012.04.031) (PMID:22658674)

Book Sections

This list was generated on Sun Jun 15 12:06:05 2025 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

EHA Research Mobility Grant 2024
European Hematology Association
2024 - 2024
Structural basis of TRIM25 and RIPLET mediated antiviral response
EMBL Heidelberg
2023 - 2023
Understanding the Roles of Cellular RNA-Binding Proteins in HIV-1 Infection
Wellcome Trust
2023 - 2023
RBP-ReguNet
EPSRC EU Guarantee
2023 - 2027
Towards the discovery of cellular RNA-binding proteins with master regulatory roles in virus infection
European Research Council
2021 - 2026
Proteome-Wide Identification of RNA-Binding Proteins Playing Critical Roles in Virus Infection
Medical Research Council
2021 - 2022
DRMOV
European Commission
2021 - 2021

Supervision

Qin, Zhiling
The host and viral factors influencing SARS-CoV2 infection and replication dynamics in culture models and human patient samples

Research datasets

Jump to: 2023 | 2021

Number of items: 3.

2023

Rainey, S., Geoghegan, V., Lefteri, D. , Ant, T., Martinez, J. , McNamara, C., Kamel, W. , de Laurent, Z., Castello, A. and Sinkins, S. (2023) Differences in proteome perturbations caused by the Wolbachia strain wAu suggest multiple mechanisms of Wolbachia-mediated antiviral activity. [Data Collection]

2021

Wickenhagen, A., Sugrue, E. , Lytras, S., Kuchi, S., Noerenberg, M. , Turnbull, M. , Loney, C. , Herder, V., Allan, J., Jarmson, I., Cameron Ruiz, N., Varjak, M. , Pinto, R. , Lee, J. Y., Iselin, L., Palmalux, N., Stewart, D., Swingler, S., Greenwood, E. J. D., Crozier, T. W. M., Gu, Q. , Davies, E., Clohisey, S., Wang, B., Trindade Maranhã Costa, F., Santana, M. F., Carlos de Lima Ferreira, L., Murphy, L., Fawkes, A., Meynert, A., Grimes, G., ISARICC investigators, , Da Silva Filho, J. , Marti, M. , Hughes, J. , Stanton, R. J., Wang, E. C. Y., Ho, A. , Davis, I., Jarrett, R. , Castello, A. , Robertson, D. , Semple, M. G., Openshaw, P. J. M., Palmarini, M. , Lehner, P. J., Baillie, K., Rihn, S. and Wilson, S. (2021) A Prenylated dsRNA Sensor Protects Against Severe COVID-19. [Data Collection]

Shaw, A., Rihn, S. , Mollentze, N. , Wickenhagen, A., Stewart, D., Orton, R. , Kuchi, S., Bakshi, S., Collados Rodriguez, M. , Turnbull, M. , Busby, J., Gu, Q. , Smollett, K., Bamford, C., Sugrue, E. , Johnson, P. , Da Silva Filipe, A. , Castello, A. , Streicker, D. , Robertson, D. , Palmarini, M. and Wilson, S. (2021) The 'antiviral state' has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. [Data Collection] (Unpublished)

This list was generated on Sun Jun 15 18:26:56 2025 BST.

A head and shoulders shot of Professor Alfredo Castello

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Professor Alfredo Castello

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