Dr Elaine Butterly

  • Honorary Clinical Lecturer (School of Health & Wellbeing)

Biography

Dr Elaine Butterly graduated in 2011 from the University of Glasgow with MBChB with honours. This followed from a BSc(Med Sci) intercalated degree in 2009 in Developmental Medicine.

Since graduation she has worked in clinical training in the NHS, now dual accrediting in higher specialist training in Diabetes and Endocrinology and General Internal Medicine. In 2014 she achieved membership of the Royal College of Physicians (MRCP) Glasgow and has since completed the Speciality Certificate Exam (SCE) in Endocrinology and Diabetes through MRCPUK. She continues focused clinical work through an honorary contract with NHS Greater Glasgow and Clyde.

She joined the Institute of Health and Wellbeing in February 2019 as a Clinical Research Fellow within the Public Health Department focusing particular interests in the field of type 2 diabetes.

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2022 | 2021 | 2020
Number of items: 16.

2025

Wightman, H. et al. (2025) Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events. PLoS Medicine, 22(4), e1004553. (doi: 10.1371/journal.pmed.1004553) (PMID:40193407)

Hanlon, P. et al. (2025) Age and sex differences in efficacy of treatments for type 2 diabetes: a network meta-analysis. JAMA: Journal of the American Medical Association, 333(12), pp. 1062-1073. (doi: 10.1001/jama.2024.27402) (PMID:39899304) (PMCID:PMC11791772)

2024

Wei, Lili ORCID logoORCID: https://orcid.org/0000-0002-3255-3449, Butterly, Elaine, Rodríguez Pérez, Jesús ORCID logoORCID: https://orcid.org/0000-0003-3884-2046, Chowdhury, Avirup, Shemilt, Richard, Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934 and McAllister, David ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2024) Description of subgroup reporting in clinical trials of chronic diseases: a meta-epidemiological study. BMJ Open, 14(6), e081315. (doi: 10.1136/bmjopen-2023-081315) (PMID:38908852) (PMCID:PMC11328666)

Lees, J. S. et al. (2024) Participant characteristics and exclusion from phase 3/4 industry funded trials of chronic medical conditions: meta-analysis of individual participant level data. BMJ Medicine, 3(1), e000732. (doi: 10.1136/bmjmed-2023-000732) (PMID:38737200) (PMCID:PMC11085787)

2023

Crowther, Jamie ORCID logoORCID: https://orcid.org/0000-0002-6191-7870, Butterly, Elaine W., Hannigan, Laurie J. ORCID logoORCID: https://orcid.org/0000-0003-3123-5411, Guthrie, Bruce, Wild, Sarah, Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135, Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Chadwick, Fergus J. and McAllister, David ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2023) Correlations between comorbidities in trials and the community: an individual-level participant data meta-analysis. Journal of Multimorbidity and Comorbidity, 13, pp. 1-9. (doi: 10.1177/26335565231213571) (PMID:37953975) (PMCID:PMC10637135)

Hanlon, P. et al. (2023) Treatment effect modification due to comorbidity: individual participant data meta-analyses of 120 randomised controlled trials. PLoS Medicine, 20(6), e1004176. (doi: 10.1371/journal.pmed.1004176) (PMID:37279199) (PMCID:PMC10243630)

Butterly, E. W. et al. (2023) Comorbidity and health-related quality of life in people with a chronic medical condition in randomised clinical trials: an individual participant data meta-analysis. PLoS Medicine, 20(1), e1004154. (doi: 10.1371/journal.pmed.1004154) (PMID:36649256) (PMCID:PMC9844862)

2022

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Butterly, Elaine, Shah, Anoop S. V., Hannigan, Laurie J. ORCID logoORCID: https://orcid.org/0000-0003-3123-5411, Wild, Sarah H., Guthrie, Bruce, Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135, Dias, Sofia, Welton, Nicky J. and McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2022) Assessing trial representativeness using Serious Adverse Events: An observational analysis using aggregate and individual-level data from clinical trials and routine healthcare data. BMC Medicine, 20, 410. (doi: 10.1186/s12916-022-02594-9) (PMID:36303169) (PMCID:PMC9615407)

Butterly, E. et al. (2022) Calibrating a network meta-analysis of diabetes trials of sodium glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors to a representative routine population: a systematic review protocol. BMJ Open, 12(10), e066491. (doi: 10.1136/bmjopen-2022-066491) (PMID:36302574) (PMCID:PMC9621152)

Hannigan, Laurie J. ORCID logoORCID: https://orcid.org/0000-0003-3123-5411, Phillippo, David M., Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Moss, Laura ORCID logoORCID: https://orcid.org/0000-0003-4968-0900, Butterly, Elaine W., Hawkins, Neil ORCID logoORCID: https://orcid.org/0000-0003-3199-221X, Dias, Sofia, Welton, Nicky J. and McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2022) Improving the estimation of subgroup effects for clinical trial participants with multimorbidity by incorporating drug class-level information in Bayesian hierarchical models: a simulation study. Medical Decision Making, 42(2), pp. 228-240. (doi: 10.1177/0272989X211029556) (PMID:34407672) (PMCID:PMC8777306)

Lees, J. S. et al. (2022) Effect of age, sex, and morbidity count on trial attrition: meta-analysis of individual participant level data from phase 3/4 industry funded clinical trials. BMJ Medicine, 1(1), e000217. (doi: 10.1136/bmjmed-2022-000217) (PMID:36936559) (PMCID:PMC9978693)

2021

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Jani, Bhautesh D. ORCID logoORCID: https://orcid.org/0000-0001-7348-514X, Butterly, Elaine, Nicholl, Barbara ORCID logoORCID: https://orcid.org/0000-0001-5639-0130, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 and Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 (2021) An analysis of frailty and multimorbidity in 20,566 UK Biobank participants with type 2 diabetes. Communications Medicine, 1, 28. (doi: 10.1038/s43856-021-00029-9) (PMID:35602215) (PMCID:PMC9053176)

McGurnaghan, S. J. et al. (2021) Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland. Lancet Diabetes and Endocrinology, 9(2), pp. 82-93. (doi: 10.1016/S2213-8587(20)30405-8) (PMID:33357491) (PMCID:PMC7832778)

2020

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Faure, Isabella, Corcoran, Neave ORCID logoORCID: https://orcid.org/0000-0001-8460-2532, Butterly, Elaine, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, McAllister, David ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 and Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 (2020) Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis. Lancet Healthy Longevity, 1(3), e106-e116. (doi: 10.1016/S2666-7568(20)30014-3) (PMID:33313578) (PMCID:PMC7721684)

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Butterly, Elaine, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, Siebert, Stefan ORCID logoORCID: https://orcid.org/0000-0002-1802-7311, Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 and McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2020) Identifying frailty in trials: an analysis of individual participant data from trials of novel pharmacological interventions. BMC Medicine, 18, 309. (doi: 10.1186/s12916-020-01752-1) (PMID:33087107) (PMCID:PMC7579922)

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Fauré, Isabella, Corcoran, Neave ORCID logoORCID: https://orcid.org/0000-0001-8460-2532, Butterly, Elaine, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 and Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 (2020) The identification and prevalence of frailty in diabetes mellitus and association with clinical outcomes: a systematic review protocol. BMJ Open, 10(9), e037476. (doi: 10.1136/bmjopen-2020-037476) (PMID:32873673) (PMCID:PMC7467518)

This list was generated on Sat Jun 14 23:57:53 2025 BST.
Jump to: Articles
Number of items: 16.

Articles

Wightman, H. et al. (2025) Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events. PLoS Medicine, 22(4), e1004553. (doi: 10.1371/journal.pmed.1004553) (PMID:40193407)

Hanlon, P. et al. (2025) Age and sex differences in efficacy of treatments for type 2 diabetes: a network meta-analysis. JAMA: Journal of the American Medical Association, 333(12), pp. 1062-1073. (doi: 10.1001/jama.2024.27402) (PMID:39899304) (PMCID:PMC11791772)

Wei, Lili ORCID logoORCID: https://orcid.org/0000-0002-3255-3449, Butterly, Elaine, Rodríguez Pérez, Jesús ORCID logoORCID: https://orcid.org/0000-0003-3884-2046, Chowdhury, Avirup, Shemilt, Richard, Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934 and McAllister, David ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2024) Description of subgroup reporting in clinical trials of chronic diseases: a meta-epidemiological study. BMJ Open, 14(6), e081315. (doi: 10.1136/bmjopen-2023-081315) (PMID:38908852) (PMCID:PMC11328666)

Lees, J. S. et al. (2024) Participant characteristics and exclusion from phase 3/4 industry funded trials of chronic medical conditions: meta-analysis of individual participant level data. BMJ Medicine, 3(1), e000732. (doi: 10.1136/bmjmed-2023-000732) (PMID:38737200) (PMCID:PMC11085787)

Crowther, Jamie ORCID logoORCID: https://orcid.org/0000-0002-6191-7870, Butterly, Elaine W., Hannigan, Laurie J. ORCID logoORCID: https://orcid.org/0000-0003-3123-5411, Guthrie, Bruce, Wild, Sarah, Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135, Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Chadwick, Fergus J. and McAllister, David ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2023) Correlations between comorbidities in trials and the community: an individual-level participant data meta-analysis. Journal of Multimorbidity and Comorbidity, 13, pp. 1-9. (doi: 10.1177/26335565231213571) (PMID:37953975) (PMCID:PMC10637135)

Hanlon, P. et al. (2023) Treatment effect modification due to comorbidity: individual participant data meta-analyses of 120 randomised controlled trials. PLoS Medicine, 20(6), e1004176. (doi: 10.1371/journal.pmed.1004176) (PMID:37279199) (PMCID:PMC10243630)

Butterly, E. W. et al. (2023) Comorbidity and health-related quality of life in people with a chronic medical condition in randomised clinical trials: an individual participant data meta-analysis. PLoS Medicine, 20(1), e1004154. (doi: 10.1371/journal.pmed.1004154) (PMID:36649256) (PMCID:PMC9844862)

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Butterly, Elaine, Shah, Anoop S. V., Hannigan, Laurie J. ORCID logoORCID: https://orcid.org/0000-0003-3123-5411, Wild, Sarah H., Guthrie, Bruce, Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135, Dias, Sofia, Welton, Nicky J. and McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2022) Assessing trial representativeness using Serious Adverse Events: An observational analysis using aggregate and individual-level data from clinical trials and routine healthcare data. BMC Medicine, 20, 410. (doi: 10.1186/s12916-022-02594-9) (PMID:36303169) (PMCID:PMC9615407)

Butterly, E. et al. (2022) Calibrating a network meta-analysis of diabetes trials of sodium glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors to a representative routine population: a systematic review protocol. BMJ Open, 12(10), e066491. (doi: 10.1136/bmjopen-2022-066491) (PMID:36302574) (PMCID:PMC9621152)

Hannigan, Laurie J. ORCID logoORCID: https://orcid.org/0000-0003-3123-5411, Phillippo, David M., Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Moss, Laura ORCID logoORCID: https://orcid.org/0000-0003-4968-0900, Butterly, Elaine W., Hawkins, Neil ORCID logoORCID: https://orcid.org/0000-0003-3199-221X, Dias, Sofia, Welton, Nicky J. and McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2022) Improving the estimation of subgroup effects for clinical trial participants with multimorbidity by incorporating drug class-level information in Bayesian hierarchical models: a simulation study. Medical Decision Making, 42(2), pp. 228-240. (doi: 10.1177/0272989X211029556) (PMID:34407672) (PMCID:PMC8777306)

Lees, J. S. et al. (2022) Effect of age, sex, and morbidity count on trial attrition: meta-analysis of individual participant level data from phase 3/4 industry funded clinical trials. BMJ Medicine, 1(1), e000217. (doi: 10.1136/bmjmed-2022-000217) (PMID:36936559) (PMCID:PMC9978693)

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Jani, Bhautesh D. ORCID logoORCID: https://orcid.org/0000-0001-7348-514X, Butterly, Elaine, Nicholl, Barbara ORCID logoORCID: https://orcid.org/0000-0001-5639-0130, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 and Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 (2021) An analysis of frailty and multimorbidity in 20,566 UK Biobank participants with type 2 diabetes. Communications Medicine, 1, 28. (doi: 10.1038/s43856-021-00029-9) (PMID:35602215) (PMCID:PMC9053176)

McGurnaghan, S. J. et al. (2021) Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland. Lancet Diabetes and Endocrinology, 9(2), pp. 82-93. (doi: 10.1016/S2213-8587(20)30405-8) (PMID:33357491) (PMCID:PMC7832778)

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Faure, Isabella, Corcoran, Neave ORCID logoORCID: https://orcid.org/0000-0001-8460-2532, Butterly, Elaine, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, McAllister, David ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 and Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 (2020) Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis. Lancet Healthy Longevity, 1(3), e106-e116. (doi: 10.1016/S2666-7568(20)30014-3) (PMID:33313578) (PMCID:PMC7721684)

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Butterly, Elaine, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, Siebert, Stefan ORCID logoORCID: https://orcid.org/0000-0002-1802-7311, Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 and McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 (2020) Identifying frailty in trials: an analysis of individual participant data from trials of novel pharmacological interventions. BMC Medicine, 18, 309. (doi: 10.1186/s12916-020-01752-1) (PMID:33087107) (PMCID:PMC7579922)

Hanlon, Peter ORCID logoORCID: https://orcid.org/0000-0002-5828-3934, Fauré, Isabella, Corcoran, Neave ORCID logoORCID: https://orcid.org/0000-0001-8460-2532, Butterly, Elaine, Lewsey, Jim ORCID logoORCID: https://orcid.org/0000-0002-3811-8165, McAllister, David A. ORCID logoORCID: https://orcid.org/0000-0003-3550-1764 and Mair, Frances S. ORCID logoORCID: https://orcid.org/0000-0001-9780-1135 (2020) The identification and prevalence of frailty in diabetes mellitus and association with clinical outcomes: a systematic review protocol. BMJ Open, 10(9), e037476. (doi: 10.1136/bmjopen-2020-037476) (PMID:32873673) (PMCID:PMC7467518)

This list was generated on Sat Jun 14 23:57:53 2025 BST.

profile photo Elaine Butterly