Dr William McLean
- Clinical Senior Lecturer (Dental School)
William McLean graduated from the University of Wales College of Medicine Dental School in 1997. During his undergraduate years, he intercalated and was awarded a Bachelor of Science (Hons) Degree in Dental Science. Following graduation, he was awarded an Action Research Training Fellowship to pursue his PhD. The following four years were spent at Harvard Medical School Department of Cell Biology investigating craniofacial and skeletal development. In 2002, he took up a position as a lecturer at Manchester University in the School of Biological Sciences. In 2004, he returned to clinical practice and subsequently undertook postgraduate training in Endodontology.
As a Senior Lecturer/Honorary Consultant in Endodontics, he is the academic lead for Undergraduate Endodontics at the University of Glasgow Dental School, programme co-ordinator for the MSc Endodontics and lead for the Glasgow Endodontology Group. He currently is treasurer of the British Endodontic Society and a Dental School Tutor for the Royal College of Physicians and Surgeons of Glasgow.
Glasgow Endodontology Group
The Glasgow Endodontology Group (GEG) is a multidisciplinary group working on the immunopathobiology and microbiology of endodontic disease towards the development of novel strategies in its clinical management. The group consists of bioengineers, microbiologists, biologists and clinicians.
The overall aim of the group is to develop strategies to manage endodontic disease using regenerative procedures.
Race for the Space - interaction between cells, surfaces and therapeutics in endodontic regeneration
Endodontic disease, an infection of the root canal space is a significant cause of dental morbidity worldwide. Endodontic infections can result from dental trauma, carious lesions, non-carious tooth surface loss or on rare occasions from periodontal infection progressing to the root apex. This condition, in which complex biofilms form within the intricate anatomy of the root canal system is treated by mechanical debridement, chemical disinfection and subsequently obturation of the space in a process termed root canal treatment. One million root canal treatments are performed under the National Health Service each year, costing £50.5 million. Outcomes vary considerably for the established treatments. It is clear that although allowing patients to retain teeth, it is far from ideal, and despite many “advances” in clinical endodontics we have seen little improvement in outcomes. It has been proposed that the ideal outcome for endodontic therapy would be to establish, through regenerative endodontics, a healthy pulp within the cleansed and disinfected root canal system.
- Understanding endodontic biofilms, inter-kingdom relationships within them, and managing them to prepare for regeneration
- Inflammation in regeneration
- Orchestrating cellular invasion and organisation in regeneration
- Dr Will McLean – Senior Clinical Lecturer/Honorary Consultant in Endodontics (Dental School)
- Professor Gordon Ramage – Professor of Microbiology (Dental School)
- Dr Alun Scott - Senior Lecturer in Restorative Dentistry
- Dr Chris Nile - Senior Lecturer in Oral Biology (School of Dental Sciences, Newcastle University)
- Professor Matthew Dalby - Professor of Cell Engineering (Institute of Molecular Cell and Systems Biology)
- Khawlah Albashaireh – PhD Student
- Om-Alkhir Shanta – PhD Student
- Saeed Alqahtani - PhD Student
- Sumaya Abusrewil - PhD Student
- Fatima Dantata – MSc Student
- Abdullmajeed Al tokheus – MSc Student
- Sonia Devi Khamuani – MSc Student
Glasgow Endodontology Group: @GlasgowEndo
Will McLean: @McLeanDr
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Do interkingdom polymicrobial biofilms impede the treatment of apical periodontitis?
2018 - 2020