Dr Alexander Harkiss
- Honorary Research Associate (School of Chemistry)
email:
Alexander.Harkiss@glasgow.ac.uk
School of Chemistry, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ
Biography
Research Associate in the Cooke Research Group
Research interests
Research groups
Publications
2024
Riley, Leanne M. ORCID: https://orcid.org/0000-0003-0615-9752, Marshall, Olivia, Harkiss, Alexander H., Senn, Hans M.
ORCID: https://orcid.org/0000-0001-8232-5957 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2024)
Synthesis of β-pyridyl α-amino acids: conformationally sensitive charge transfer-based fluorophores.
Organic Letters, 26(25),
pp. 5391-5395.
(doi: 10.1021/acs.orglett.4c01951)
(PMID:38865167)
(PMCID:PMC11217948)
2023
Songsri, Sineenard, Harkiss, Alexander H. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2023)
Synthesis and photophysical properties of charge-transfer based pyrimidine-derived ∝-amino acids.
Journal of Organic Chemistry, 88(18),
pp. 13214-13224.
(doi: 10.1021/acs.joc.3c01437)
(PMID:37621156)
(PMCID:PMC10507667)
Uno, Shinpei, Harkiss, Alexander H., Chowdhury, Roy, Caldwell, Stuart T. ORCID: https://orcid.org/0000-0003-1604-3462, Prime, Tracy A., James, Andrew M., Gallagher, Brendan, Prudent, Julien, Hartley, Richard C.
ORCID: https://orcid.org/0000-0003-1033-5405 and Murphy, Michael P.
(2023)
Incorporating a polyethyleneglycol linker to enhance the hydrophilicity of mitochondria‐targeted triphenylphosphonium constructs.
ChemBioChem, 24(11),
e202200774.
(doi: 10.1002/cbic.202200774)
(PMID:36917207)
(PMCID:PMC10946768)
2022
Cariello, Michele ORCID: https://orcid.org/0000-0001-9699-3710, Pant, Namrata, Harkiss, Alexander H., Tracey, Frances M., Cameron, Joseph
ORCID: https://orcid.org/0000-0001-8622-8353, Skabara, Peter J.
ORCID: https://orcid.org/0000-0001-7319-0464, Holliman, Peter J., Docampo, Pablo
ORCID: https://orcid.org/0000-0001-6164-4748 and Cooke, Graeme
ORCID: https://orcid.org/0000-0003-0890-5720
(2022)
Synthesis of SOT-OH and its application as a building block for the synthesis of new dimeric and trimeric Spiro-OMeTAD materials.
Molecular Systems Design and Engineering, 7(8),
pp. 899-905.
(doi: 10.1039/D2ME00038E)
2020
Bell, Jonathan D., Harkiss, Alexander H., Nobis, David, Malcolm, Eilidh, Knuhtsen, Astrid, Wellaway, Christopher R., Jamieson, Andrew G. ORCID: https://orcid.org/0000-0003-1726-7353, Magennis, Steven W.
ORCID: https://orcid.org/0000-0002-4327-8366 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2020)
Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence.
Chemical Communications, 56(12),
pp. 1887-1890.
(doi: 10.1039/C9CC09064A)
(PMID:31956866)
2019
Bell, Jonathan D., Morgan, Timaeus E.F., Buijs, Ned, Harkiss, Alexander H., Wellaway, Christopher R. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2019)
Synthesis and photophysical properties of benzotriazole-derived unnatural α -amino acids.
Journal of Organic Chemistry, 84(16),
pp. 10436-10448.
(doi: 10.1021/acs.joc.9b01685)
(PMID:31340638)
Harkiss, Alexander H., Bell, Jonathan D., Knuhtsen, Astrid, Jamieson, Andrew G. ORCID: https://orcid.org/0000-0003-1726-7353 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2019)
Synthesis and fluorescent properties of β-pyridyl α-amino acids.
Journal of Organic Chemistry, 84(5),
pp. 2879-2890.
(doi: 10.1021/acs.joc.9b00036)
(PMID:30726078)
2018
Bell, Jonathan D., Harkiss, Alexander H., Wellaway, Christopher R. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2018)
Stereoselective synthesis of 2,6-trans-4-oxopiperidines using an acid-mediated 6-endo-trig cyclisation.
Organic and Biomolecular Chemistry, 16(35),
pp. 6410-6422.
(doi: 10.1039/C8OB01363B)
(PMID:30011344)
Harkiss, Alexander H. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2018)
Access to 2,6-disubstituted 4-oxopiperidines using a 6-endo-trig cyclization: stereoselective synthesis of spruce alkaloid and (+)-241D.
Journal of Organic Chemistry, 83(1),
pp. 535-542.
(doi: 10.1021/acs.joc.7b02799)
(PMID:29218988)
2016
Sharif, Salaheddin A.I., Calder, Ewen D.D., Harkiss, Alexander, Maduro, Marie and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2016)
Synthesis of allylic amide functionalized 2H-chromenes and coumarins using a one-pot overman rearrangement and gold(I)-catalyzed hydroarylation.
Journal of Organic Chemistry, 81(20),
pp. 9810-9819.
(doi: 10.1021/acs.joc.6b01881)
(PMID:27680202)
Harkiss, Alexander and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2016)
Recent advances in the synthesis and application of fluorescent α-amino acids.
Organic and Biomolecular Chemistry, 14(38),
pp. 8911-8921.
(doi: 10.1039/C6OB01715K)
(PMID:27714204)
2015
Gilfillan, Lynne, Artschwager, Raik, Harkiss, Alexander H., Liskamp, Rob M.J. ORCID: https://orcid.org/0000-0001-8897-8975 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2015)
Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones.
Organic and Biomolecular Chemistry, 13(15),
pp. 4514-4523.
(doi: 10.1039/C5OB00364D)
(PMID:25774874)
2014
Calder, Ewen D.D., McGonagle, Fiona I., Harkiss, Alexander H., McGonagle, Grant A. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2014)
Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids.
Journal of Organic Chemistry, 79(16),
pp. 7633-7648.
(doi: 10.1021/jo5014492)
(PMID:25060853)
Articles
Riley, Leanne M. ORCID: https://orcid.org/0000-0003-0615-9752, Marshall, Olivia, Harkiss, Alexander H., Senn, Hans M.
ORCID: https://orcid.org/0000-0001-8232-5957 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2024)
Synthesis of β-pyridyl α-amino acids: conformationally sensitive charge transfer-based fluorophores.
Organic Letters, 26(25),
pp. 5391-5395.
(doi: 10.1021/acs.orglett.4c01951)
(PMID:38865167)
(PMCID:PMC11217948)
Songsri, Sineenard, Harkiss, Alexander H. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2023)
Synthesis and photophysical properties of charge-transfer based pyrimidine-derived ∝-amino acids.
Journal of Organic Chemistry, 88(18),
pp. 13214-13224.
(doi: 10.1021/acs.joc.3c01437)
(PMID:37621156)
(PMCID:PMC10507667)
Uno, Shinpei, Harkiss, Alexander H., Chowdhury, Roy, Caldwell, Stuart T. ORCID: https://orcid.org/0000-0003-1604-3462, Prime, Tracy A., James, Andrew M., Gallagher, Brendan, Prudent, Julien, Hartley, Richard C.
ORCID: https://orcid.org/0000-0003-1033-5405 and Murphy, Michael P.
(2023)
Incorporating a polyethyleneglycol linker to enhance the hydrophilicity of mitochondria‐targeted triphenylphosphonium constructs.
ChemBioChem, 24(11),
e202200774.
(doi: 10.1002/cbic.202200774)
(PMID:36917207)
(PMCID:PMC10946768)
Cariello, Michele ORCID: https://orcid.org/0000-0001-9699-3710, Pant, Namrata, Harkiss, Alexander H., Tracey, Frances M., Cameron, Joseph
ORCID: https://orcid.org/0000-0001-8622-8353, Skabara, Peter J.
ORCID: https://orcid.org/0000-0001-7319-0464, Holliman, Peter J., Docampo, Pablo
ORCID: https://orcid.org/0000-0001-6164-4748 and Cooke, Graeme
ORCID: https://orcid.org/0000-0003-0890-5720
(2022)
Synthesis of SOT-OH and its application as a building block for the synthesis of new dimeric and trimeric Spiro-OMeTAD materials.
Molecular Systems Design and Engineering, 7(8),
pp. 899-905.
(doi: 10.1039/D2ME00038E)
Bell, Jonathan D., Harkiss, Alexander H., Nobis, David, Malcolm, Eilidh, Knuhtsen, Astrid, Wellaway, Christopher R., Jamieson, Andrew G. ORCID: https://orcid.org/0000-0003-1726-7353, Magennis, Steven W.
ORCID: https://orcid.org/0000-0002-4327-8366 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2020)
Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence.
Chemical Communications, 56(12),
pp. 1887-1890.
(doi: 10.1039/C9CC09064A)
(PMID:31956866)
Bell, Jonathan D., Morgan, Timaeus E.F., Buijs, Ned, Harkiss, Alexander H., Wellaway, Christopher R. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2019)
Synthesis and photophysical properties of benzotriazole-derived unnatural α -amino acids.
Journal of Organic Chemistry, 84(16),
pp. 10436-10448.
(doi: 10.1021/acs.joc.9b01685)
(PMID:31340638)
Harkiss, Alexander H., Bell, Jonathan D., Knuhtsen, Astrid, Jamieson, Andrew G. ORCID: https://orcid.org/0000-0003-1726-7353 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2019)
Synthesis and fluorescent properties of β-pyridyl α-amino acids.
Journal of Organic Chemistry, 84(5),
pp. 2879-2890.
(doi: 10.1021/acs.joc.9b00036)
(PMID:30726078)
Bell, Jonathan D., Harkiss, Alexander H., Wellaway, Christopher R. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2018)
Stereoselective synthesis of 2,6-trans-4-oxopiperidines using an acid-mediated 6-endo-trig cyclisation.
Organic and Biomolecular Chemistry, 16(35),
pp. 6410-6422.
(doi: 10.1039/C8OB01363B)
(PMID:30011344)
Harkiss, Alexander H. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2018)
Access to 2,6-disubstituted 4-oxopiperidines using a 6-endo-trig cyclization: stereoselective synthesis of spruce alkaloid and (+)-241D.
Journal of Organic Chemistry, 83(1),
pp. 535-542.
(doi: 10.1021/acs.joc.7b02799)
(PMID:29218988)
Sharif, Salaheddin A.I., Calder, Ewen D.D., Harkiss, Alexander, Maduro, Marie and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2016)
Synthesis of allylic amide functionalized 2H-chromenes and coumarins using a one-pot overman rearrangement and gold(I)-catalyzed hydroarylation.
Journal of Organic Chemistry, 81(20),
pp. 9810-9819.
(doi: 10.1021/acs.joc.6b01881)
(PMID:27680202)
Harkiss, Alexander and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2016)
Recent advances in the synthesis and application of fluorescent α-amino acids.
Organic and Biomolecular Chemistry, 14(38),
pp. 8911-8921.
(doi: 10.1039/C6OB01715K)
(PMID:27714204)
Gilfillan, Lynne, Artschwager, Raik, Harkiss, Alexander H., Liskamp, Rob M.J. ORCID: https://orcid.org/0000-0001-8897-8975 and Sutherland, Andrew
ORCID: https://orcid.org/0000-0001-7907-5766
(2015)
Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones.
Organic and Biomolecular Chemistry, 13(15),
pp. 4514-4523.
(doi: 10.1039/C5OB00364D)
(PMID:25774874)
Calder, Ewen D.D., McGonagle, Fiona I., Harkiss, Alexander H., McGonagle, Grant A. and Sutherland, Andrew ORCID: https://orcid.org/0000-0001-7907-5766
(2014)
Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids.
Journal of Organic Chemistry, 79(16),
pp. 7633-7648.
(doi: 10.1021/jo5014492)
(PMID:25060853)
Research datasets
2023
Uno, S., Harkiss, A., Chowdhury, R., Caldwell, S. , Prime, T. A., James, A. M., Gallagher, B., Prudent, J., Hartley, R. and Murphy, M. (2023) Incorporating a Polyethyleneglycol Linker to Enhance the Hydrophilicity of Mitochondria-Targeted Triphenylphosphonium Constructs. [Data Collection]