Dr Mark Jackson
- Research Associate (Clinical Research Garscube)
telephone:
0141 330 3984
email:
Mark.Jackson.2@glasgow.ac.uk
Publications
2024
Vens, C. et al. (2024) A joint physics and radiobiology DREAM team vision - towards better response prediction models to advance radiotherapy. Radiotherapy and Oncology, 196, 110277. (doi: 10.1016/j.radonc.2024.110277) (PMID:38670264)
Derby, S. et al. (2024) Concurrent olaparib and radiotherapy in elderly patients with newly diagnosed glioblastoma: the phase I dose escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)
Derby, S. et al. (2024) Concurrent olaparib and radiation therapy in older patients with newly diagnosed glioblastoma: the phase 1 dose-escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)
Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)
2023
Westerhof, Lotus M., Noonan, Jonathan, Hargrave, Kerrie E., Chimbayo, Elizabeth T., Cheng, Zhiling, Purnell, Thomas, Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Borcherding, Nicholas and MacLeod, Megan K.L.
ORCID: https://orcid.org/0000-0003-1843-8580
(2023)
Multifunctional cytokine production marks influenza A virus specific CD4 T cells with high expression of survival molecules.
European Journal of Immunology, 53(11),
2350559.
(doi: 10.1002/eji.202350559)
(PMID:37490492)
Halstead, S. K. et al. (2023) Serum anti‐GM2 and anti‐GalNAc‐GD1a ganglioside IgG antibodies are biomarkers for immune‐mediated polyneuropathies in cats. Journal of the Peripheral Nervous System, 28(1), pp. 32-40. (doi: 10.1111/jns.12529) (PMID:36573790)
2022
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Halstead, S.K. et al. (2022) Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis. Journal of Small Animal Practice, 63(2), pp. 104-112. (doi: 10.1111/jsap.13439) (PMID:34791652)
Jackson, M. R. et al. (2022) Low-dose lung radiotherapy for COVID-19 lung disease: a preclinical efficacy study in a bleomycin model of pneumonitis. International Journal of Radiation Oncology, Biology, Physics, 112(1), pp. 197-211. (doi: 10.1016/j.ijrobp.2021.08.029) (PMID:34478832) (PMCID:PMC8406661)
2021
Bavelaar, B. M. et al. (2021) Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides. Molecular Pharmaceutics, 18(10), pp. 3820-3831. (doi: 10.1021/acs.molpharmaceut.1c00442) (PMID:34449222) (PMCID:PMC8493550)
Koessinger, A. L. et al. (2021) Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics. bioRxiv, (doi: 10.1101/2021.06.13.448232)
2020
Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Ashton, Miranda, Koessinger, Anna L., Dick, Craig, Verheij, Marcel and Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2020)
Mesothelioma cells depend on the anti-apoptotic protein Bcl-xL for survival and are sensitized to ionizing radiation by BH3-mimetics.
International Journal of Radiation Oncology, Biology, Physics, 106(4),
pp. 867-877.
(doi: 10.1016/j.ijrobp.2019.11.029)
(PMID:31786278)
Gomez-Roman, Natividad ORCID: https://orcid.org/0000-0002-2325-7517, Chong, Ming Y., Chahal, Sandeep K., Caragher, Seamus P., Jackson, Mark R.
ORCID: https://orcid.org/0000-0003-3843-2995, Stevenson, Katrina H., Dongre, Sidhartha A. and Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2020)
Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ.
Molecular Cancer Therapeutics, 19(2),
pp. 575-589.
(doi: 10.1158/1535-7163.MCT-18-1320)
(PMID:31672763)
2019
Gilbert, Hamish T. J., Mallikarjun, Venkatesh, Dobre, Oana ORCID: https://orcid.org/0000-0003-1968-5428, Jackson, Mark R.
ORCID: https://orcid.org/0000-0003-3843-2995, Pedley, Robert, Gilmore, Andrew P., Richardson, Stephen M. and Swift, Joe
(2019)
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading.
Nature Communications, 10,
4149.
(doi: 10.1038/s41467-019-11923-1)
(PMID:31515493)
(PMCID:PMC6742657)
Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Bavelaar, Bas M., Waghorn, Philip A., Gill, Martin R., El-Sagheer, Afaf H., Brown, Tom, Tarsounas, Madalena and Vallis, Katherine A.
(2019)
Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells.
Cancer Research, 79(18),
pp. 4627-4637.
(doi: 10.1158/0008-5472.CAN-18-3594)
(PMID:31311806)
2017
Waghorn, Philip A., Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Gouverneur, Veronique and Vallis, Katherine A.
(2017)
Targeting telomerase with radiolabeled inhibitors.
European Journal of Medicinal Chemistry, 125,
pp. 117-129.
(doi: 10.1016/j.ejmech.2016.09.028)
(PMID:27657809)
(PMCID:PMC5154340)
2016
Cho, Inchul, Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995 and Swift, Joe
(2016)
Roles of cross-membrane transport and signaling in the maintenance of cellular homeostasis.
Cellular and Molecular Bioengineering, 9(2),
pp. 234-246.
(doi: 10.1007/s12195-016-0439-6)
(PMID:27335609)
(PMCID:PMC4893050)
2013
Jackson, M.R. ORCID: https://orcid.org/0000-0003-3843-2995, Falzone, N. and Vallis, K.A.
(2013)
Advances in anticancer radiopharmaceuticals.
Clinical Oncology, 25(10),
pp. 604-609.
(doi: 10.1016/j.clon.2013.06.004)
(PMID:23870756)
Articles
Vens, C. et al. (2024) A joint physics and radiobiology DREAM team vision - towards better response prediction models to advance radiotherapy. Radiotherapy and Oncology, 196, 110277. (doi: 10.1016/j.radonc.2024.110277) (PMID:38670264)
Derby, S. et al. (2024) Concurrent olaparib and radiotherapy in elderly patients with newly diagnosed glioblastoma: the phase I dose escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)
Derby, S. et al. (2024) Concurrent olaparib and radiation therapy in older patients with newly diagnosed glioblastoma: the phase 1 dose-escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)
Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)
Westerhof, Lotus M., Noonan, Jonathan, Hargrave, Kerrie E., Chimbayo, Elizabeth T., Cheng, Zhiling, Purnell, Thomas, Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Borcherding, Nicholas and MacLeod, Megan K.L.
ORCID: https://orcid.org/0000-0003-1843-8580
(2023)
Multifunctional cytokine production marks influenza A virus specific CD4 T cells with high expression of survival molecules.
European Journal of Immunology, 53(11),
2350559.
(doi: 10.1002/eji.202350559)
(PMID:37490492)
Halstead, S. K. et al. (2023) Serum anti‐GM2 and anti‐GalNAc‐GD1a ganglioside IgG antibodies are biomarkers for immune‐mediated polyneuropathies in cats. Journal of the Peripheral Nervous System, 28(1), pp. 32-40. (doi: 10.1111/jns.12529) (PMID:36573790)
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Halstead, S.K. et al. (2022) Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis. Journal of Small Animal Practice, 63(2), pp. 104-112. (doi: 10.1111/jsap.13439) (PMID:34791652)
Jackson, M. R. et al. (2022) Low-dose lung radiotherapy for COVID-19 lung disease: a preclinical efficacy study in a bleomycin model of pneumonitis. International Journal of Radiation Oncology, Biology, Physics, 112(1), pp. 197-211. (doi: 10.1016/j.ijrobp.2021.08.029) (PMID:34478832) (PMCID:PMC8406661)
Bavelaar, B. M. et al. (2021) Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides. Molecular Pharmaceutics, 18(10), pp. 3820-3831. (doi: 10.1021/acs.molpharmaceut.1c00442) (PMID:34449222) (PMCID:PMC8493550)
Koessinger, A. L. et al. (2021) Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics. bioRxiv, (doi: 10.1101/2021.06.13.448232)
Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Ashton, Miranda, Koessinger, Anna L., Dick, Craig, Verheij, Marcel and Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2020)
Mesothelioma cells depend on the anti-apoptotic protein Bcl-xL for survival and are sensitized to ionizing radiation by BH3-mimetics.
International Journal of Radiation Oncology, Biology, Physics, 106(4),
pp. 867-877.
(doi: 10.1016/j.ijrobp.2019.11.029)
(PMID:31786278)
Gomez-Roman, Natividad ORCID: https://orcid.org/0000-0002-2325-7517, Chong, Ming Y., Chahal, Sandeep K., Caragher, Seamus P., Jackson, Mark R.
ORCID: https://orcid.org/0000-0003-3843-2995, Stevenson, Katrina H., Dongre, Sidhartha A. and Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2020)
Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ.
Molecular Cancer Therapeutics, 19(2),
pp. 575-589.
(doi: 10.1158/1535-7163.MCT-18-1320)
(PMID:31672763)
Gilbert, Hamish T. J., Mallikarjun, Venkatesh, Dobre, Oana ORCID: https://orcid.org/0000-0003-1968-5428, Jackson, Mark R.
ORCID: https://orcid.org/0000-0003-3843-2995, Pedley, Robert, Gilmore, Andrew P., Richardson, Stephen M. and Swift, Joe
(2019)
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading.
Nature Communications, 10,
4149.
(doi: 10.1038/s41467-019-11923-1)
(PMID:31515493)
(PMCID:PMC6742657)
Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Bavelaar, Bas M., Waghorn, Philip A., Gill, Martin R., El-Sagheer, Afaf H., Brown, Tom, Tarsounas, Madalena and Vallis, Katherine A.
(2019)
Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells.
Cancer Research, 79(18),
pp. 4627-4637.
(doi: 10.1158/0008-5472.CAN-18-3594)
(PMID:31311806)
Waghorn, Philip A., Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995, Gouverneur, Veronique and Vallis, Katherine A.
(2017)
Targeting telomerase with radiolabeled inhibitors.
European Journal of Medicinal Chemistry, 125,
pp. 117-129.
(doi: 10.1016/j.ejmech.2016.09.028)
(PMID:27657809)
(PMCID:PMC5154340)
Cho, Inchul, Jackson, Mark R. ORCID: https://orcid.org/0000-0003-3843-2995 and Swift, Joe
(2016)
Roles of cross-membrane transport and signaling in the maintenance of cellular homeostasis.
Cellular and Molecular Bioengineering, 9(2),
pp. 234-246.
(doi: 10.1007/s12195-016-0439-6)
(PMID:27335609)
(PMCID:PMC4893050)
Jackson, M.R. ORCID: https://orcid.org/0000-0003-3843-2995, Falzone, N. and Vallis, K.A.
(2013)
Advances in anticancer radiopharmaceuticals.
Clinical Oncology, 25(10),
pp. 604-609.
(doi: 10.1016/j.clon.2013.06.004)
(PMID:23870756)