Dr Denise Hough

  • Lecturer (Physiology Ageing & Welfare)

telephone: 01413303705
email: Denise.Hough@glasgow.ac.uk

R235B Level 2, Jarret Building, School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, G61 1QH

Import to contacts

ORCID iDhttps://orcid.org/0000-0002-5478-693X

Biography

University of Stellenbosch, South Africa:

BSc Animal Biotechnology

Hons Biochemistry

PhD Biochemistry

Post-doctoral training:

2012-2013, Western Cape Department of Agriculture in collaboration with the University of Stellenbosch

2013-2019, University of Glasgow in the Institute of Biodiversity, Animal Health and Comparative Medicine

2018-2019, University of Glasgow in the Institute of Cardiovascular and Medical Sciences

 

Research interests

I am interested in how steroid hormone production changes dynamically over an individual's lifespan and the physiological processes that it influences. Some of my research are molecular and cellular based, such as investigations of tissue-specific steroid biosynthesis. Other areas of research utilise physiological and behavioural approaches to investigate the role of steroids during critical periods of development to program health later in life. 

Research groups

Publications

List by: Type | Date

Jump to: 2024 | 2023 | 2019 | 2018 | 2017 | 2015 | 2013 | 2012 | 2010 | 2009
Number of items: 18.

2024

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X (2024) A course coordinator's lessons learnt from the 2023-24 academic year of embracing AI in teaching practice. Intelligent Assessment in the age of AI, University of Leeds, 14 May 2024.

2023

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X and Corbishley, Alexander (2023) Guidance on responsible use of AI tools for enhanced learning – BVMS Programme. [Protocols]

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Johnstone, Iain and Gray, Joseph (2023) Life Sciences Student guidance on responsible use of AI. [Protocols]

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X (2023) Student guidance for the responsible use of AI. Association for Learning Technology Blog, 10 Oct.

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X (2023) Examples of using AI to support student learning & assessment in Life Sciences. [Website]

2019

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Robinson, J.E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Bellingham, M. ORCID logoORCID: https://orcid.org/0000-0002-3646-8989, Fleming, L.M., McLaughlin, M. ORCID logoORCID: https://orcid.org/0000-0001-5317-2090, Jama, K., Haraldsen, I.R.H., Solbakk, A.K. and Evans, N.P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 (2019) Peripubertal GnRH and testosterone co-treatment leads to increased familiarity preferences in male sheep. Psychoneuroendocrinology, 108, pp. 70-77. (doi: 10.1016/j.psyneuen.2019.06.008) (PMID:31229635) (PMCID:PMC6712355)

O'Shaughnessy, P. J. et al. (2019) Alternative (backdoor) androgen production and masculinization in the human fetus. PLoS Biology, 17(2), e3000002. (doi: 10.1371/journal.pbio.3000002) (PMID:30763313) (PMCID:PMC6375548)

2018

Muvhali, Pfunzo T., Bonato, Maud, Engelbrecht, Anel, Malecki, Irek A., Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Robinson, Jane E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Evans, Neil P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 and Cloete, Schalk W.P. (2018) The effect of extensive human presence at an early age on stress responses and reactivity of juvenile ostriches towards humans. Animals, 8(10), 175. (doi: 10.3390/ani8100175) (PMID:30301126) (PMCID:PMC6210211)

Johnston, Z. C. et al. (2018) The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester. BMC Medicine, 16, 23. (doi: 10.1186/s12916-018-1009-7) (PMID:29429410) (PMCID:PMC5808459)

2017

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Bellingham, M. ORCID logoORCID: https://orcid.org/0000-0002-3646-8989, Haraldsen, J.R., McLaughlin, M. ORCID logoORCID: https://orcid.org/0000-0001-5317-2090, Robinson, J.E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Solbakk, A.K. and Evans, N.P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 (2017) A reduction in long-term spatial memory persists after discontinuation of peripubertal GnRH agonist treatment in sheep. Psychoneuroendocrinology, 77, pp. 1-8. (doi: 10.1016/j.psyneuen.2016.11.029) (PMID:27987429) (PMCID:PMC5333793)

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Bellingham, M. ORCID logoORCID: https://orcid.org/0000-0002-3646-8989, Haraldsen, I.R.H., McLaughlin, M. ORCID logoORCID: https://orcid.org/0000-0001-5317-2090, Rennie, M., Robinson, J.E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Solbakk, A.K. and Evans, N.P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 (2017) Spatial memory is impaired by peripubertal GnRH agonist treatment and testosterone replacement in sheep. Psychoneuroendocrinology, 75, pp. 173-182. (doi: 10.1016/j.psyneuen.2016.10.016) (PMID:27837697) (PMCID:PMC5140006)

2015

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Storbeck, K., Cloete, S.W.P., Swart, A.C. and Swart, P. (2015) Relative contribution of P450c17 towards the acute cortisol response: lessons from sheep and goats. Molecular and Cellular Endocrinology, 408, pp. 107-113. (doi: 10.1016/j.mce.2015.01.018) (PMID:25597634)

2013

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Cloete, S.W.P., Swart, P. and Cloete, J.J.E. (2013) Searching for SNPs that affect sheep robustness: CYP17 SNP affects behavioural responses to psychological stress. In: 20th Association for the Advancement of Animal Breeding and Genetics Conference, Napier, New Zealand, 20-23 Oct 2013, pp. 503-506.

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Cloete, S.W.P., Storbeck, K., Swart, A.C. and Swart, P. (2013) Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17-alpha-hydroxylase/17,20-lyase (CYP17) isoforms. Journal of Animal Science, 91(3), pp. 1193-1206. (doi: 10.2527/jas.2012-5800)

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Swart, Pieter and Cloete, Schalk (2013) Exploration of the hypothalamic-pituitary-adrenal axis to improve animal welfare by means of genetic selection: lessons from the South African Merino. Animals, 3(2), pp. 442-474. (doi: 10.3390/ani3020442) (PMID:26487412) (PMCID:PMC4494397)

2012

Cloete, A.S., Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X and Cloete, S.W.P. (2012) Testing times – developing awareness while fostering research: improving health, welfare and production in South African Merinos. In: 2012 Australian and New Zealand Council for the Care of Animals in Research and Teaching Conference, Perth, W.A., Australia, 24 - 26 Jul 2012, pp. 43-48. ISBN 9780987465702

2010

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Cloete, S.W.P., Swart, P. and Storbeck, K. (2010) Improving stress coping ability: comparison between the CYP17 genotype Of Ovis Aries and Capra Hircus. In: 9th World Congress on Genetics Applied to Livestock Production, Leipzig, Germany, 1-6 Aug 2010, 0628.

2009

Van der Walt, D., Cloete, S.W.P., Storbeck, K. and Swart, P. (2009) The role of Cytochrome P450 17-alpha-Hydroxylase/ 17,20-Lyase (CYP17) in the stress coping ability in a divergently selected Merino sheep population. In: 18th Association for the Advancement of Animal Breeding and Genetics Conference, Barossa Valley, South Australia, 28 Sep - 1 Oct 2009, pp. 100-103.

This list was generated on Sun Jun 15 17:44:13 2025 BST.
Jump to: Articles | Conference or Workshop Item | Conference Proceedings | Protocols | Website
Number of items: 18.

Articles

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X (2023) Student guidance for the responsible use of AI. Association for Learning Technology Blog, 10 Oct.

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Robinson, J.E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Bellingham, M. ORCID logoORCID: https://orcid.org/0000-0002-3646-8989, Fleming, L.M., McLaughlin, M. ORCID logoORCID: https://orcid.org/0000-0001-5317-2090, Jama, K., Haraldsen, I.R.H., Solbakk, A.K. and Evans, N.P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 (2019) Peripubertal GnRH and testosterone co-treatment leads to increased familiarity preferences in male sheep. Psychoneuroendocrinology, 108, pp. 70-77. (doi: 10.1016/j.psyneuen.2019.06.008) (PMID:31229635) (PMCID:PMC6712355)

O'Shaughnessy, P. J. et al. (2019) Alternative (backdoor) androgen production and masculinization in the human fetus. PLoS Biology, 17(2), e3000002. (doi: 10.1371/journal.pbio.3000002) (PMID:30763313) (PMCID:PMC6375548)

Muvhali, Pfunzo T., Bonato, Maud, Engelbrecht, Anel, Malecki, Irek A., Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Robinson, Jane E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Evans, Neil P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 and Cloete, Schalk W.P. (2018) The effect of extensive human presence at an early age on stress responses and reactivity of juvenile ostriches towards humans. Animals, 8(10), 175. (doi: 10.3390/ani8100175) (PMID:30301126) (PMCID:PMC6210211)

Johnston, Z. C. et al. (2018) The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester. BMC Medicine, 16, 23. (doi: 10.1186/s12916-018-1009-7) (PMID:29429410) (PMCID:PMC5808459)

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Bellingham, M. ORCID logoORCID: https://orcid.org/0000-0002-3646-8989, Haraldsen, J.R., McLaughlin, M. ORCID logoORCID: https://orcid.org/0000-0001-5317-2090, Robinson, J.E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Solbakk, A.K. and Evans, N.P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 (2017) A reduction in long-term spatial memory persists after discontinuation of peripubertal GnRH agonist treatment in sheep. Psychoneuroendocrinology, 77, pp. 1-8. (doi: 10.1016/j.psyneuen.2016.11.029) (PMID:27987429) (PMCID:PMC5333793)

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Bellingham, M. ORCID logoORCID: https://orcid.org/0000-0002-3646-8989, Haraldsen, I.R.H., McLaughlin, M. ORCID logoORCID: https://orcid.org/0000-0001-5317-2090, Rennie, M., Robinson, J.E. ORCID logoORCID: https://orcid.org/0000-0002-4632-1366, Solbakk, A.K. and Evans, N.P. ORCID logoORCID: https://orcid.org/0000-0001-7395-3222 (2017) Spatial memory is impaired by peripubertal GnRH agonist treatment and testosterone replacement in sheep. Psychoneuroendocrinology, 75, pp. 173-182. (doi: 10.1016/j.psyneuen.2016.10.016) (PMID:27837697) (PMCID:PMC5140006)

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Storbeck, K., Cloete, S.W.P., Swart, A.C. and Swart, P. (2015) Relative contribution of P450c17 towards the acute cortisol response: lessons from sheep and goats. Molecular and Cellular Endocrinology, 408, pp. 107-113. (doi: 10.1016/j.mce.2015.01.018) (PMID:25597634)

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Cloete, S.W.P., Storbeck, K., Swart, A.C. and Swart, P. (2013) Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17-alpha-hydroxylase/17,20-lyase (CYP17) isoforms. Journal of Animal Science, 91(3), pp. 1193-1206. (doi: 10.2527/jas.2012-5800)

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Swart, Pieter and Cloete, Schalk (2013) Exploration of the hypothalamic-pituitary-adrenal axis to improve animal welfare by means of genetic selection: lessons from the South African Merino. Animals, 3(2), pp. 442-474. (doi: 10.3390/ani3020442) (PMID:26487412) (PMCID:PMC4494397)

Conference or Workshop Item

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X (2024) A course coordinator's lessons learnt from the 2023-24 academic year of embracing AI in teaching practice. Intelligent Assessment in the age of AI, University of Leeds, 14 May 2024.

Conference Proceedings

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Cloete, S.W.P., Swart, P. and Cloete, J.J.E. (2013) Searching for SNPs that affect sheep robustness: CYP17 SNP affects behavioural responses to psychological stress. In: 20th Association for the Advancement of Animal Breeding and Genetics Conference, Napier, New Zealand, 20-23 Oct 2013, pp. 503-506.

Cloete, A.S., Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X and Cloete, S.W.P. (2012) Testing times – developing awareness while fostering research: improving health, welfare and production in South African Merinos. In: 2012 Australian and New Zealand Council for the Care of Animals in Research and Teaching Conference, Perth, W.A., Australia, 24 - 26 Jul 2012, pp. 43-48. ISBN 9780987465702

Hough, D. ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Cloete, S.W.P., Swart, P. and Storbeck, K. (2010) Improving stress coping ability: comparison between the CYP17 genotype Of Ovis Aries and Capra Hircus. In: 9th World Congress on Genetics Applied to Livestock Production, Leipzig, Germany, 1-6 Aug 2010, 0628.

Van der Walt, D., Cloete, S.W.P., Storbeck, K. and Swart, P. (2009) The role of Cytochrome P450 17-alpha-Hydroxylase/ 17,20-Lyase (CYP17) in the stress coping ability in a divergently selected Merino sheep population. In: 18th Association for the Advancement of Animal Breeding and Genetics Conference, Barossa Valley, South Australia, 28 Sep - 1 Oct 2009, pp. 100-103.

Protocols

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X and Corbishley, Alexander (2023) Guidance on responsible use of AI tools for enhanced learning – BVMS Programme. [Protocols]

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X, Johnstone, Iain and Gray, Joseph (2023) Life Sciences Student guidance on responsible use of AI. [Protocols]

Website

Hough, Denise ORCID logoORCID: https://orcid.org/0000-0002-5478-693X (2023) Examples of using AI to support student learning & assessment in Life Sciences. [Website]

This list was generated on Sun Jun 15 17:44:13 2025 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Is the adrenal functionally altered when puberty is delayed with GnRHa?
    Society for Endocrinology
    2017 - 2017
     
  • Investigating hypothalamic mechanisms that control LH profiles in oestrous ewes from two genetically distinct lines
    British Society for Neuroendocrinology
    2017 - 2018
     

Teaching

Level 1 Biology

Level 1 Current Directions in Life Sciences

Level 4 Problems in Mammalian Reproduction

MRes Biomedical Sciences: Endocrinology in Health and Disease

Professional activities & recognition

Professional & learned societies

  • 2013: member, British Society for Neuroendocrinology
  • 2024: MVLS representative, UofG AI in Assessment and Feedback Operational Working Group
  • 2023: Chair, UofG MVLS GAINEd Steering Group
  • 2024: SBOHVM representative, UofG MVLS TELT committee
  • 2020: panel member, UofG Academic Appeals Committee
  • 2025: Reviewer, Life Sciences Misconduct Committee

Dr Denise Hough on Twitter