Dr Richard Burchmore
- Senior Lecturer (Parasitology)
telephone:
01413308612
email:
Richard.Burchmore@glasgow.ac.uk
Room 212, Tcrc, Garscube Campus, Glasgow G12 1QH
https://orcid.org/0000-0003-1663-9004Research interests
The role of membrane transporters in parasite virulence and drug susceptibility.
Current Research :
My research is focused on understanding, at the molecular level, the mechanisms by which parasites thrive in the challenging environments which they encounter. Complex phenotypes such as drug resistance and virulence are of central relevance in parasitology and are amenable to global approaches such as proteomics and metabolomics. In recent years I have brought these new technologies to bear upon the systems biology of parasites and of host:parasite interactions. In parallel, I have applied more conventional reverse genetic and biochemical approaches to specifically perturb parasite systems and to validate the results of proteomic analyses.
My primary parasite of interest is Leishmania, but I have also worked extensively with trypanosomes. Through collaborative links with other parasitologists, I have applied proteomic approaches to a diverse range of parasites, as well as to other biological systems. Current areas of research focus include understanding the role of nutrient transporters and stress responses in parasite development, virulence and drug resistance.
Publications
2023
Girasol, M. J. et al. (2023) RAD51-mediated R-loop formation acts to repair transcription associated DNA breaks driving antigenic variation in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America, 120(48), e230930612. (doi: 10.1073/pnas.2309306120) (PMID:37988471) (PMCID:PMC10691351)
Huang, Y., Jonsson, N. N. , McLaughlin, M. , Burchmore, R. , Johnson, P. C.D. , Jones, R. , McGill, S., Brady, N., Weidt, S. and Eckersall, D. (2023) Quantitative TMT-based proteomics revealing host, dietary and microbial proteins in bovine faeces including barley serpin Z4, a prominent component in the head of beer. Journal of Proteomics, 285, 104941. (doi: 10.1016/j.jprot.2023.104941) (PMID:37285906)
Kuleš, J., Rubić, I., Farkaš, V., Barić Rafaj, R., Gotić, J., Crnogaj, M., Burchmore, R. , Eckersall, D. , Mrljak, V. and Leisewitz, A. L. (2023) Serum proteome profiling of naturally acquired Babesia rossi infection in dogs. Scientific Reports, 13, 10249. (doi: 10.1038/s41598-023-37312-9) (PMID:37353646) (PMCID:PMC10290096)
Ungogo, M. A. et al. (2023) Cloning and characterization of Trypanosoma congolense and T. vivax nucleoside transporters reveal the potential of P1-type carriers for the discovery of broad-spectrum nucleoside-based therapeutics against Animal African Trypanosomiasis. International Journal of Molecular Sciences, 24(4), 3144. (doi: 10.3390/ijms24043144) (PMID:36834557) (PMCID:PMC9960827)
Nguyen, T. X. et al. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part I: serum proteomes. Journal of Proteomics, 270, 104740. (doi: 10.1016/j.jprot.2022.104740) (PMID:36191802)
Nguyen, T. X., Agazzo, A., McGill, S., Weidt, S., Han, Q. H., Gelemanović, A., McLaughlin, M. , Savoini, G., Eckersall, P. D. and Burchmore, R. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part II: ileum proteomes. Journal of Proteomics, 270, 104739. (doi: 10.1016/j.jprot.2022.104739) (PMID:36174954)
2022
Anuntasomboon, P., Siripattanapipong, S., Unajak, S., Choowongkomon, K., Burchmore, R. , Leelayoova, S., Mungthin, M. and E-kobon, T. (2022) Identification of a conserved maxicircle and unique minicircles as part of the mitochondrial genome of Leishmania martiniquensis strain PCM3 in Thailand. Parasites and Vectors, 15, 459. (doi: 10.1186/s13071-022-05592-1) (PMID:36510327) (PMCID:PMC9743726)
Alpizar-Sosa, E. A. et al. (2022) Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLoS Neglected Tropical Diseases, 16(9), e0010779. (doi: 10.1371/journal.pntd.0010779) (PMID:36170238) (PMCID:PMC9581426)
Anuntasomboon, P., Siripattanapipong, S., Unajak, S., Choowongkomon, K., Burchmore, R. , Leelayoova, S., Mungthin, M. and E-kobon, T. (2022) Making the most of its short reads: a bioinformatics workflow for analysing the short-read-only data of Leishmania orientalis (formerly named Leishmania siamensis) isolate PCM2 in Thailand. Biology, 11(9), 1272. (doi: 10.3390/biology11091272) (PMID:36138751) (PMCID:PMC9495971)
Díaz, M. L., Burgess, K., Burchmore, R. , Gómez, M. A., Gómez-Ochoa, S. A., Echeverría, L. E., Morillo, C. and González, C. I. (2022) Metabolomic profiling of end-stage heart failure secondary to chronic Chagas cardiomyopathy. International Journal of Molecular Sciences, 23(18), 10456. (doi: 10.3390/ijms231810456) (PMID:36142367) (PMCID:PMC9499603)
Aldfer, M. M. , AlSiari, T. A., Elati, H. A.A. , Natto, M. J., Alfayez, I. A., Campagnaro, G. D., Sani, B., Burchmore, R. J. S. , Diallinas, G. and De Koning, H. (2022) Nucleoside transport and nucleobase uptake null mutants in Leishmania mexicana for the routine expression and characterization of purine and pyrimidine transporters. International Journal of Molecular Sciences, 23(15), 8139. (doi: 10.3390/ijms23158139) (PMID:35897714) (PMCID:PMC9331716)
Huang, Y., Burchmore, R. , Jonsson, N. N. , Johnson, P. C.D. and Eckersall, P. D. (2022) Technical report: In-gel sample preparation prior to proteomic analysis of bovine faeces increases protein identifications by removal of high molecular weight glycoproteins. Journal of Proteomics, 261, 104573. (doi: 10.1016/j.jprot.2022.104573) (PMID:35351658)
Nguyen, T. X. et al. (2022) Abundance of plasma proteins in response to divergent ratios of dietary ω6:ω3 fatty acids in gestating and lactating sows using a quantitative proteomics approach. Journal of Proteomics, 260, 104562. (doi: 10.1016/j.jprot.2022.104562) (PMID:35314360)
Hulme, H. et al. (2022) Mapping the influence of the gut microbiota on small molecules across the microbiome gut brain axis. Journal of the American Society for Mass Spectrometry, 33(4), pp. 649-659. (doi: 10.1021/jasms.1c00298) (PMID:35262356) (PMCID:PMC9047441)
Anuntasomboon, P., Siripattanapipong, S., Unajak, S., Choowongkomon, K., Burchmore, R. , Leelayoova, S., Mungthin, M. and E-kobon, T. (2022) Comparative draft genomes of Leishmania orientalis isolate PCM2 (formerly named Leishmania siamensis ) and Leishmania martiniquensis isolate PCM3 from the southern province of Thailand. Biology and Environment: Proceedings of the Royal Irish Academy, 11(4), e515. (doi: 10.3390/biology11040515) (PMID:35453714) (PMCID:PMC9031872)
Meewan, J. et al. (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14(2), e439. (doi: 10.3390/pharmaceutics14020439) (PMID:35214171) (PMCID:PMC8877401)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
McGill, S., Burchmore, R. J.S. , Pomeroy, P. P. and Kennedy, M. W. (2022) Is a little enough? Paucity of immune proteins in serum of precocial neonates of a marine carnivoran—the Atlantic grey seal. Frontiers in Ecology and Evolution, 9, 802510. (doi: 10.3389/fevo.2021.802510)
Fernández, D., Segura, C., Arman, M., McGill, S., Burchmore, R. and Lopera-Mesa, T. (2022) Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets. Clinical Proteomics, 19(1), 1. (doi: 10.1186/s12014-021-09337-7) (PMID:34991449) (PMCID:PMC8903537)
McGill, S., Burchmore, R. J. S. , Pomeroy, P. P. and Kennedy, M. W. (2022) Mirror image serum lipid carrier protein profiles in pup and lactating mother Atlantic grey seals reflect contrasting resource mobilisation challenges. Frontiers in Marine Science, 9, 944214. (doi: 10.3389/fmars.2022.944214)
2021
Orrapin, S., Roytrakul, S., Phaonakrop, N., Thaisakun, S., Tragoolpua, K., Intorasoot, A., McGill, S., Burchmore, R. and Intorasoot, S. (2021) Fungicidal activity of recombinant javanicin against Cryptococcus neoformans is associated with intracellular target(s) involved in carbohydrate and energy metabolic processes. Molecules, 26(22), 7011. (doi: 10.3390/molecules26227011)
2020
Nguyen, T. X., Agazzi, A., Comi, M., Bontempo, V., Guido, I., Panseri, S., Sauerwein, H., Eckersall, P. D. , Burchmore, R. and Savoini, G. (2020) Effects of low ω6:ω3 ratio in sow diet and seaweed supplement in piglet diet on performance, colostrum and milk fatty acid profiles, and oxidative status. Animals, 10(11), 2049. (doi: 10.3390/ani10112049) (PMID:33167599) (PMCID:PMC7694489)
Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)
Varjak, M. , Gestuveo, R. J., Burchmore, R. , Schnettler, E. and Kohl, A. (2020) aBravo is a novel Aedes aegypti antiviral protein that interacts with, but acts independently of, the exogenous siRNA pathway effector Dicer 2. Viruses, 12(7), 748. (doi: 10.3390/v12070748)
Damianou, A., Burge, R. J., Catta-Preta, C. M.C., Geoghegan, V., Nievas, Y. R., Newling, K., Brown, E., Burchmore, R. , Rodenko, B. and Mottram, J. C. (2020) Essential roles for deubiquitination in Leishmania life cycle progression. PLoS Pathogens, 16(6), e1008455. (doi: 10.1371/journal.ppat.1008455) (PMID:32544189) (PMCID:PMC7319358)
Royle, J. , Ramírez-Santana, C., Akpunarlieva, S., Donald, C. L. , Gestuveo, R. J., Anaya, J.-M., Merits, A., Burchmore, R. , Kohl, A. and Varjak, M. (2020) Glucose-regulated protein 78 interacts with Zika virus envelope protein and contributes to a productive infection. Viruses, 12(5), 524. (doi: 10.3390/v12050524)
Hulme, H. et al. (2020) Microbiome-derived carnitine mimics as novel mediators of gut-brain axis communication. Science Advances, 6(11), eaax6328. (doi: 10.1126/sciadv.aax6328) (PMID:32195337) (PMCID:PMC7065903)
Naula, C. and Burchmore, R. (2020) 2D gel electrophoresis analysis of leishmania proteomes. In: Michels, P. A. M., Ginger, M. L. and Zilberstein, D. (eds.) Trypanosomatids: Methods and Protocols. Series: Methods in Molecular Biology. Springer US: New York, pp. 577-586. ISBN 9781071602942 (doi: 10.1007/978-1-0716-0294-2_34)
2019
Vargas, D. A., Prieto, M. D., Martínez-Valencia, A. J., Cossio, A., Burgess, K. E.V., Burchmore, R. J.S. and Gómez, M. A. (2019) Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis. Frontiers in Pharmacology, 10, 657. (doi: 10.3389/fphar.2019.00657) (PMID:31281253) (PMCID:PMC6595045)
Johnston, K., Kim, D.-H., Kerkhoven, E. J., Burchmore, R. , Barrett, M. P. and Achcar, F. (2019) Mapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U-13C-labelled substrates and LC-MS. Bioscience Reports, 39(5), BSR2018160. (doi: 10.1042/BSR20181601) (PMID:31028136) (PMCID:PMC6522824)
Ormsby, M. J., Grahame, E., Burchmore, R. and Davies, R. L. (2019) Comparative bioinformatic and proteomic approaches to evaluate the outer membrane proteome of the fish pathogen Yersinia ruckeri. Journal of Proteomics, 199, pp. 135-147. (doi: 10.1016/j.jprot.2019.02.014) (PMID:30831250) (PMCID:PMC6447952)
Acosta, H., Burchmore, R. , Naula, C. , Gualdrón-López, M., Quintero-Troconis, E., Cáceres, A. J., Michels, P. A.M., Concepción, J. L. and Quiñones, W. (2019) Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes. Molecular and Biochemical Parasitology, 229, pp. 62-74. (doi: 10.1016/j.molbiopara.2019.02.008) (PMID:30831156) (PMCID:PMC7082770)
McCanney, G. A., Mcgrath, M. A., Otto, T. D. , Burchmore, R. , Yates, E. A., Bavington, C. D., Willison, H. J. , Turnbull, J. E. and Barnett, S. C. (2019) Low sulfated heparins target multiple proteins for central nervous system repair. Glia, 67(4), pp. 668-687. (doi: 10.1002/glia.23562) (PMID:30585359)
Keuss, M. J., Hjerpe, R., Hsia, O., Gourlay, R., Burchmore, R. , Trost, M. and Kurz, T. (2019) Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death. EMBO Journal, 38, e100024. (doi: 10.15252/embj.2018100024) (PMID:30804002) (PMCID:PMC6418418)
Kaab, H., Bain, M. M. , Bartley, K., Turnbull, F. , Wright, H. W., Nisbet, A. J., Burchmore, R. and Eckersall, P. D. (2019) Serum and acute phase protein changes in laying hens, infested with poultry red mite. Poultry Science, 98(2), pp. 679-687. (doi: 10.3382/ps/pey431) (PMID:30239853)
2018
Prakash, A. S., Kabli, A. M.F., Bulleid, N. and Burchmore, R. (2018) Mix-and-match proteomics: using advanced iodoacetyl tandem mass tag multiplexing to investigate cysteine oxidation changes with respect to protein expression. Analytical Chemistry, 90(24), pp. 14173-14180. (doi: 10.1021/acs.analchem.8b02517) (PMID:30452864)
Morlon-Guyot, J., El Hajj, H., Martin, K., Fois, A., Carrillo, A., Berry, L., Burchmore, R. , Meissner, M. , Lebrun, M. and Daher, W. (2018) A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis. Cellular Microbiology, 20(11), e12870. (doi: 10.1111/cmi.12870) (PMID:29911335)
Santana, A. M., Silva, D. G.,, Thomas, F. C., Bernardes, P. A., Pizauro, L. J.L., Santana, C. H., Burchmore, R. J.S. , Eckersall, P. D. and Fagliari, J. J. (2018) Blood serum acute phase proteins and iron dynamics during acute phase response of Salmonella enterica serotype Dublin experimentally infected buffalo calves. Veterinary Immunology and Immunopathology, 203, pp. 30-39. (doi: 10.1016/j.vetimm.2018.07.014) (PMID:30243370)
De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)
Santana, A. M., Thomas, F. C., Silva, D. G., McCulloch, E., Vidal, A. M.C., Burchmore, R. J.S. , Fagliari, J. J. and Eckersall, P. D. (2018) Reference 1D and 2D electrophoresis maps for potential disease related proteins in milk whey from lactating buffaloes and blood serum from buffalo calves (Water buffalo, Bubalus bubalis). Research in Veterinary Science, 118, pp. 449-465. (doi: 10.1016/j.rvsc.2018.04.010) (PMID:29734122)
Bilić, P., Guillemin, N., Kovačević, A., Ljubić, B. B., Jović, I., Galan, A., Eckersall, P. D. , Burchmore, R. and Mrljak, V. (2018) Serum proteome profiling in canine idiopathic dilated cardiomyopathy using TMT-based quantitative proteomics approach. Journal of Proteomics, 179, pp. 110-121. (doi: 10.1016/j.jprot.2018.03.007) (PMID:29530679)
Kovarova, J., Pountain, A. W. , Wildridge, D., Weidt, S., Bringaud, F., Burchmore, R. J.S. , Achcar, F. and Barrett, M. P. (2018) Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana. PLoS Pathogens, 14(3), e1006953. (doi: 10.1371/journal.ppat.1006953) (PMID:29554142) (PMCID:PMC5882173)
Nayak, A., Akpunarlieva, S., Barrett, M. and Burchmore, R. (2018) A defined medium for Leishmania culture allows definition of essential amino acids. Experimental Parasitology, 185, pp. 39-52. (doi: 10.1016/j.exppara.2018.01.009) (PMID:29326050)
Williams, J. J.L., Al-Otaiq, N., Mullen, W. , Burchmore, R. , Liu, L., Baillie, G. S. , Schaper, F., Pilch, P. F. and Palmer, T. M. (2018) Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability. Nature Communications, 9, 168. (doi: 10.1038/s41467-017-02585-y) (PMID:29330478) (PMCID:PMC5766592)
Ferrazza, R. d. A., Dos Santos Schmidt, E. M., Mihm Carmichael, M., de Souza, F. F., Burchmore, R. , Sartori, R., Eckersall, P. D. and Ferreira, J. C. P. (2018) Quantitative proteomic profiling of bovine follicular fluid during follicle development. Biology of Reproduction, 97(6), pp. 835-849. (doi: 10.1093/biolre/iox148) (PMID:29149247)
2017
Akpunarlieva, S. and Burchmore, R. (2017) The role of membrane transporters in Leishmania virulence. Emerging Topics in Life Sciences, 1(6), pp. 601-611. (doi: 10.1042/etls20170119)
Lowe, A. D., Bawazeer, S., Watson, D. G., McGill, S., Burchmore, R. J.S. , Pomeroy, P.P. (P.) and Kennedy, M. W. (2017) Rapid changes in Atlantic grey seal milk from birth to weaning – immune factors and indicators of metabolic strain. Scientific Reports, 7, 16093. (doi: 10.1038/s41598-017-16187-7) (PMID:29170469) (PMCID:PMC5700954)
Martinez-Subiela, S., Horvatic, A., Escribano, D., Pardo-Marin, L., Kocaturk, M., Mrljak, V., Burchmore, R. , Ceron, J. J. and Yilmaz, Z. (2017) Identification of novel biomarkers for treatment monitoring in canine leishmaniosis by high-resolution quantitative proteomic analysis. Veterinary Immunology and Immunopathology, 191, pp. 60-67. (doi: 10.1016/j.vetimm.2017.08.004) (PMID:28895868)
Mwenechanya, R. et al. (2017) Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), e0005649. (doi: 10.1371/journal.pntd.0005649) (PMID:28622334) (PMCID:PMC5498063)
Rojas, F., Koszela, J., Búa, J., Llorente, B., Burchmore, R. , Auer, M., Mottram, J. C. and Téllez-Iñón, M. T. (2017) The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei. PLoS Neglected Tropical Diseases, 11(6), e0005626. (doi: 10.1371/journal.pntd.0005626) (PMID:28609481) (PMCID:PMC5507466)
HULME, H. E. et al. (2017) Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection. Scientific Reports, 7, 2786. (doi: 10.1038/s41598-017-03100-5) (PMID:28584281) (PMCID:PMC5459799)
O'Reilly, E. L., Burchmore, R. J. , Sparks, N. H. and Eckersall, P. D. (2017) The effect of microbial challenge on the intestinal proteome of broiler chickens. Proteome Science, 15, 10. (doi: 10.1186/s12953-017-0118-0) (PMID:28572745) (PMCID:PMC5450085)
Schrama, D., Richard, N., Silva, T. S., Figueiredo, F. A., Conceição, L. E.C., Burchmore, R. , Eckersall, D. and Rodrigues, P. M.L. (2017) Enhanced dietary formulation to mitigate winter thermal stress in gilthead sea bream (Sparus aurata): a 2D-DIGE plasma proteome study. Fish Physiology and Biochemistry, 43(2), pp. 603-617. (doi: 10.1007/s10695-016-0315-2) (PMID:27882445)
Marcos-López, M., Rodger, H. D., O'Connor, I., Braceland, M., Burchmore, R. J.S. , Eckersall, P. and MacCarthy, E. (2017) A proteomic approach to assess the host response in gills of farmed Atlantic salmon Salmo salar L. affected by amoebic gill disease. Aquaculture, 470, pp. 1-10. (doi: 10.1016/j.aquaculture.2016.12.009)
Lindeberg, H., Burchmore, R. J.S. and Kennedy, M. W. (2017) Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation. Royal Society Open Science, 4(3), 161085. (doi: 10.1098/rsos.161085) (PMID:28405395) (PMCID:PMC5383852)
Akpunarlieva, S., Weidt, S., Lamasudin, D., Naula, C. , Henderson, D., Barrett, M. , Burgess, K. and Burchmore, R. (2017) Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania. Journal of Proteomics, 155, pp. 85-98. (doi: 10.1016/j.jprot.2016.12.009) (PMID:28040509)
2016
Lobo-Rojas, Á. E., González-Marcano, E. B., Valera-Vera, E. A., Acosta, H. R., Quiñones, W. A., Burchmore, R. J.S. , Concepción, J. L. and Cáceres, A. J. (2016) Trypanosoma cruzi contains two galactokinases; molecular and biochemical characterization. Parasitology International, 65(5 Pt A), pp. 472-482. (doi: 10.1016/j.parint.2016.06.008) (PMID:27312997)
Ormsby, M. J., Caws, T., Burchmore, R. , Wallis, T., Verner-Jeffreys, D. W. and Davies, R. L. (2016) Yersinia ruckeri isolates recovered from diseased Atlantic Salmon (Salmo salar) in Scotland are more diverse than those from Rainbow Trout (Oncorhynchus mykiss) and represent distinct subpopulations. Applied and Environmental Microbiology, 82(19), pp. 5785-5794. (doi: 10.1128/aem.01173-16) (PMID:27451448) (PMCID:PMC5038039)
Mudaliar, M. et al. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. Molecular BioSystems, 12(9), pp. 2748-2761. (doi: 10.1039/C6MB00290K) (PMID:27412694) (PMCID:PMC5048399)
Thomas, F., Mudaliar, M. , Tassi, R., Mcneilly, T., Burchmore, R. , Burgess, K., Herzyk, P. , Zadoks, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics. Molecular BioSystems, 12(9), pp. 2762-2769. (doi: 10.1039/C6MB00289G) (PMID:27412568)
Thomas, F., Mullen, W. , Tassi, R., Ramírez-Torres, A., Mudaliar, M. , Mcneilly, T., Zadoks, R. , Burchmore, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics. Molecular BioSystems, 12(9), pp. 2735-2747. (doi: 10.1039/C6MB00239K) (PMID:27412456) (PMCID:PMC5048397)
Tsiropoulou, S., Montezano, A., Scott, A., Burchmore, R.J. and Touyz, R.M. (2016) PS 07-14 vascular protein oxidation and redox proteomics in hypertension. Journal of Hypertension, 34, e287. (doi: 10.1097/01.hjh.0000500678.85921.bc)
Grewal, J. S. et al. (2016) PNT1 is a C11 cysteine peptidase essential for replication of the trypanosome kinetoplast. Journal of Biological Chemistry, 291, pp. 9492-9500. (doi: 10.1074/jbc.M116.714972) (PMID:26940875) (PMCID:PMC4850289)
2015
Tsiropoulou, S., Montezano, A.C., Scott, A., Burchmore, R.J. and Touyz, R. (2015) 41 Vascular protein oxidation and redox proteomics in human hypertension. Heart, 101(Suppl), A13-A14. (doi: 10.1136/heartjnl-2015-308734.41)
Griffiths, K., Rong, H., Wang, H., Zhang, Z., Zhang, T., Watson, D. G., Burchmore, R. , Loeffler, I.K. and Kennedy, M. (2015) Prolonged transition time between colostrum and mature milk in a bear, the giant panda, Ailuropoda melanoleuca. Royal Society Open Science, 2, 150395. (doi: 10.1098/rsos.150395)
Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)
Hajjaran, H., Mohammadi Bazargani, M., Mohebali, M., Burchmore, R. , Hosseini Salekdeh, G., Kazemi-Rad, E. and Khoramizadeh, M. (2015) Comparison of the proteome profiling of Iranian isolates of Leishmania tropica, L. major and L. infantum by two-dimensional electrophoresis (2-DE) and mass-spectrometry. Iranian Journal of Parasitology, 10(4), pp. 530-540. (PMID:26811718) (PMCID:PMC4724828)
Fyfe, C.D., Grinter, R., Josts, I., Mosbahi, K., Roszak, A.W., Cogdell, R.J. , Wall, D.M. , Burchmore, R.J.S. , Byron, O. and Walker, D. (2015) Structure of protease-cleaved escherichia coliα-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallographica. Section D: Biological Crystallography, 71(7), pp. 1478-1486. (doi: 10.1107/s1399004715008548) (PMID:26143919) (PMCID:PMC4498604)
Hajjaran, H., Mousavi, P., Burchmore, R. , Mohebali, M., Mohammadi Bazargani, M., Hosseini Salekdeh, G., Kazemi-Rad, E. and Khoramizadeh, M. R. (2015) Comparative proteomic profiling of Leishmania tropica: investigation of a case infected with simultaneous cutaneous and viscerotropic leishmaniasis by 2-dimentional electrophoresis and mass spectrometry. Iranian Journal of Parasitology, 10(3), pp. 366-380. (PMID:26622292) (PMCID:PMC4662737)
Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Wilson, D., Herzyk, P. , Eckersall, P. and Zadoks, R. (2015) Using label-free quantitative proteomics and untargeted metabolomics to study bovine mastitis. In: Science with Impact – BSAS Annual Conference 2015, University of Chester, UK, 14-15 Apr 2015, p. 70. (doi: 10.1017/S2040470015000023)
2014
Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Herzyk, P. , Eckersall, P. and Zadoks, R. (2014) Integrative label-free quantitative proteomics study in mastitis. In: Final Showcase Meeting of Farm Animal Proteomics, Milan, Italy, 17-18 Nov 2014, pp. 98-101. ISBN 9789086868100 (doi: 10.3920/978-90-8686-810-0)
Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93(1), pp. 199-211. (doi: 10.1111/mmi.12651) (PMID:24846743) (PMCID:PMC4249723)
Shafie, I. N.F., McLaughlin, M. , Burchmore, R. , Lim, M. A. A., Montague, P., Johnston, P. E.J. , Penderis, J. and Anderson, T. J. (2014) The chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog. Cell Stress and Chaperones, 19(3), pp. 311-320. (doi: 10.1007/s12192-013-0457-4)
Daneshvar, H., Mahmmodi, Z., Kamiabi, H., Phillips, R. S. and Burchmore, R. (2014) Dogs vaccinated with gentamicin-attenuated Leishmania infantum or infected with wild-type parasite can be distinguished by Western blotting. Parasite Immunology, 36(5), pp. 218-224. (doi: 10.1111/pim.12108)
Kuleš, J., Mrljak, V., Rafaj, R., Selanec, J., Burchmore, R. and Eckersall, P. D. (2014) Identification of serum biomarkers in dogs naturally infected with Babesia canis canis using a proteomic approach. BMC Veterinary Research, 10(1), p. 111. (doi: 10.1186/1746-6148-10-111)
Daneshvar, H., Namazi, M. J., Kamiabi, H., Burchmore, R. , Cleaveland, S. and Phillips, S. (2014) Gentamicin-attenuated leishmania infantum vaccine: protection of dogs against canine visceral leishmaniosis in endemic area of southeast of Iran. PLoS Neglected Tropical Diseases, 8(4), e2757. (doi: 10.1371/journal.pntd.0002757) (PMID:24743691) (PMCID:PMC3990512)
Munday, J. C. et al. (2014) Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. Journal of Antimicrobial Chemotherapy, 69(3), pp. 651-663. (doi: 10.1093/jac/dkt442) (PMID:24235095) (PMCID:PMC3922157)
Ceciliani, F., Eckersall, D. , Burchmore, R. and Lecchi, C. (2014) Proteomics in veterinary medicine: applications and trends in disease pathogenesis and diagnostics. Veterinary Pathology, 51(2), pp. 351-362. (doi: 10.1177/0300985813502819)
Burchmore, R. (2014) Mapping pathways to drug resistance with proteomics. Expert Review of Proteomics, 11(1), pp. 1-3. (doi: 10.1586/14789450.2014.871497)
2013
Kerkhoven, E. J. et al. (2013) Handling uncertainty in dynamic models: the pentose phosphate pathway in trypanosoma brucei. PLoS Computational Biology, 9(12), e1003371. (doi: 10.1371/journal.pcbi.1003371) (PMID:24339766) (PMCID:PMC3854711)
Millerioux, Y. et al. (2013) The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control. Molecular Microbiology, 90(1), pp. 114-129. (doi: 10.1111/mmi.12351) (PMID:23899193) (PMCID:PMC4034587)
Morrice, N. and Burchmore, R. (2013) Editorial. Journal of Proteomics, 88, pp. 1-3. (doi: 10.1016/j.jprot.2013.05.035)
Roncada, P., Stipetic, L.H., Bonizzi, L., Burchmore, R.J.S. and Kennedy, M.W. (2013) Proteomics as a tool to explore human milk in health and disease. Journal of Proteomics, 88, pp. 47-57. (doi: 10.1016/j.jprot.2013.04.008)
Rujeni, N., Nausch, N., Midzi, N., Cowan, G.J., Burchmore, R. , Cavanagh, D.R., Taylor, D.W., Mduluza, T. and Mutapi, F. (2013) Immunological consequences of antihelminthic treatment in preschool children exposed to urogenital schistosome infection. Journal of Tropical Medicine, 2013, 283619. (doi: 10.1155/2013/283619) (PMID:23840222) (PMCID:PMC3687481)
Atherton, M.J., Braceland, M., Fontaine, S. , Waterston, M.M., Burchmore, R.J. , Eadie, S., Eckersall, P.D. and Morris, J.S. (2013) Changes in the serum proteome of canine lymphoma identified by electrophoresis and mass spectrometry. Veterinary Journal, 196(3), pp. 320-324. (doi: 10.1016/j.tvjl.2012.12.010)
Atherton, M.J., Braceland, M., Harvie, J., Burchmore, R.J. , Eadie, S., Eckersall, P.D. and Morris, J.S. (2013) Characterisation of the normal canine serum proteome using a novel electrophoretic technique combined with mass spectrometry. Veterinary Journal, 196(3), pp. 315-319. (doi: 10.1016/j.tvjl.2012.12.011)
Feng, X., Rodriguez-Contreras, D., Polley, T., Lye, L.-F., Scott, D., Burchmore, R.J.S. , Beverley, S.M. and Landfear, S.M. (2013) 'Transient' genetic suppression facilitates generation of hexose transporter null mutants inLeishmania mexicana. Molecular Microbiology, 87(2), pp. 412-429. (doi: 10.1111/mmi.12106)
Bain, M.M. , McDade, K., Burchmore, R. , Law, A., Wilson, P.W., Schmutz, M., Preisinger, R. and Dunn, I.C. (2013) Enhancing the egg's natural defence against bacterial penetration by increasing cuticle deposition. Animal Genetics, 44(6), pp. 661-668. (doi: 10.1111/age.12071)
Burchmore, R. (2013) Proteomics at the host: pathogen interface. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, p. 37. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_11)
Kuleš, J., Mrljak, B., Rafaj, R. B., Selanec, J., Burchmore, R. and Eckersall, P. D. (2013) A proteomic analysis of canine serum during the course of babesiosis. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, pp. 135-138. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_36)
Monnerat, S., Almeida Costa, C.I., Forkert, A.C., Benz, C., Hamilton, A., Tetley, L., Burchmore, R. , Novo, C., Mottram, J.C. and Hammarton, T.C. (2013) Identification and functional characterisation of CRK12:CYC9, a novel cyclin-dependent kinase (CDK)-cyclin complex in Trypanosoma brucei. PLoS ONE, 8(6), e67327. (doi: 10.1371/journal.pone.0067327) (PMID:23805309) (PMCID:PMC3689728)
O'Reilly, E.L., Burchmore, R.J. , Eckersall, P.D. and Sparks, N.H.C. (2013) The effect of microbial challenge on the intestinal proteome of broiler chickens. British Poultry Abstracts, 9(1), pp. 5-6. (doi: 10.1080/17466202.2013.842677)
O'Reilly, E. L., Burchmore, R. J. , Eckersall, P. D. and Sparks, N. H. (2013) The effect of microbial challenge on the intestinal proteome of broiler chickens. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, pp. 143-146. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_38)
Schrama, D., Richard, N., Silva, T. S., Conceição, L. E. C., Dias, J. P., Eckersall, D. , Burchmore, R. and Rodrigues, P. M. (2013) Biomarkers of winter disease in gilthead seabream: a proteomics approach. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, pp. 175-178. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_45)
2012
Burchmore, R. (2012) Parasites in the brain? The search for sleeping sickness biomarkers. Expert Review of Anti-Infective Therapy, 10(11), pp. 1283-1286. (doi: 10.1586/ERI.12.124)
Daneshvar, H., Sedghy, F., Dabiri, S., Kamiabi, H., Molaei, M.M., Phillips, S. and Burchmore, R. (2012) Alteration in mononuclear cell subpopulations in dogs immunized with gentamicin-attenuated Leishmania infantum. Parasitology, 139(13), pp. 1689-1696. (doi: 10.1017/S0031182012001187)
Burgess, K.E.V. and Burchmore, R.J.S. (2012) Strategies to dissect parasite proteomes. Parasitology, 139(9), pp. 1119-1130. (doi: 10.1017/S0031182011002368)
Ginger, M.L., McKean, P.G., Burchmore, R.J.S. and Grant, K.M. (2012) Proteomic insights into parasite biology. Parasitology, 139(9), pp. 1101-1102. (doi: 10.1017/S0031182012000947)
Walker, J., Gongora, R., Vasquez, J.J., Drummelsmith, J., Burchmore, R. , Roy, G., Ouellette, M., Gomez, M.A. and Saravia, N.G. (2012) Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis. Molecular and Biochemical Parasitology, 183(2), pp. 166-176. (doi: 10.1016/j.molbiopara.2012.03.002) (PMID:22449941)
E-komon, T., Burchmore, R. , Herzyk, P. and Davies, R. (2012) Predicting the outer membrane proteome of Pasteurella multocida based on consensus prediction enhanced by results integration and manual confirmation. BMC Bioinformatics, 13(1), 63. (doi: 10.1186/1471-2105-13-63) (PMID:22540951) (PMCID:PMC3403877)
McNamara, L.E., Burchmore, R.J.S. , Riehle, M.O. , Herzyk, P. , Biggs, M.J.P., Wilkinson, C.D.W., Curtis, A.S.G. and Dalby, M.J. (2012) The role of microtopography in cellular mechanotransduction. Biomaterials, 33(10), pp. 2835-2847. (doi: 10.1016/j.biomaterials.2011.11.047)
Braceland, M., Bickerdike, R., Cockerill, D., Burchmore, R. , Weir, W. and Eckersall, D. (2012) Proteomics in biomarker detection and monitoring of pancreas disease (PD) in atlantic salmon (Salmo salar). In: 3rd Managing Committee Meeting and 2nd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002, Vilamoura, Portugal, 12-13 Apr 2012, pp. 87-90. ISBN 9789086861958 (doi: 10.3920/978-90-8686-751-6_20)
Daneshvar, H., Wyllie, S., Phillips, S., Hagan, P. and Burchmore, R. (2012) Comparative proteomics profiling of a gentamicin-attenuated Leishmania infantum cell line identifies key changes in parasite thiol-redox metabolism. Journal of Proteomics, 75(5), pp. 1463-1471. (doi: 10.1016/j.jprot.2011.11.018)
Kuboki, T., Kantawong, F., Burchmore, R. , Dalby, M.J. and Kidoaki, S. (2012) 2D-DIGE proteomic analysis of mesenchymal stem cell cultured on the elasticity-tunable hydrogels. Cell Structure and Function, 37(2), pp. 127-139. (doi: 10.1247/csf.12012)
McNamara, L.E., Kantawong, F., Dalby, M.J. , Riehle, M.O. and Burchmore, R.J.S. (2012) Preventing and troubleshooting artefacts in saturation labelled fluorescence 2D difference gel electrophoresis (saturation DiGE). Proteomics, 11(24), pp. 4610-4621. (doi: 10.1002/pmic.201100135)
O'Reilly, E.L., Burchmore, R.J. , Sandilands, V., Sparks, N.H., Walls, C. and Eckersall, P.D. (2012) The plasma proteome and acute phase proteins of broiler chickens with gait abnormalities. In: Rodrigues, P., Eckersall, D. and de Almeida, A. (eds.) Farm Animal Proteomics: Proceedings of the 3rd Managing Committee Meeting and 2nd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002. Series: Topics in safety, reliability, and quality (18). Wageningen Academic Publishers: Wageningen, pp. 177-180. ISBN 9789086861958 (doi: 10.3920/978-90-8686-751-6_42)
Tiengwe, C., Marcello, L., Farr, H., Gadelha, C., Burchmore, R. , Barry, J.D., Bell, S.D. and McCulloch, R. (2012) Identification of ORC1/CDC6-interacting factors in trypanosoma brucei reveals critical features of origin recognition complex architecture. PLoS ONE, 7(3), e32674. (doi: 10.1371/journal.pone.0032674) (PMID:22412905) (PMCID:PMC3297607)
Vincent, I.M. , Creek, D.J., Burgess, K., Woods, D.J., Burchmore, R.J.S. and Barrett, M.P. (2012) Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei. PLoS Neglected Tropical Diseases, 6(5), e1618. (doi: 10.1371/journal.pntd.0001618) (PMID:22563508) (PMCID:PMC3341325)
2011
Hounsome, J. D.A., Baillie, S., Noofeli, M., Riboldi-Tunnicliffe, A., Burchmore, R. J.S. , Isaacs, N. W. and Davies, R. L. (2011) Outer membrane protein A of bovine and ovine isolates of mannheimia haemolytica is surface exposed and contains host species-specific epitopes. Infection and Immunity, 79(11), pp. 4332-4341. (doi: 10.1128/IAI.05469-11) (PMID:21896777) (PMCID:PMC3257919)
Higon, M. et al. (2011) Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni. Parasitology, 138(12), pp. 1607-1619. (doi: 10.1017/S0031182011000412)
Barrett, M.P. , Vincent, I.M. , Burchmore, R.J.S. , Kazibwe, A.J.N. and Matovu, E. (2011) Drug resistance in human African trypanosomiasis. Future Microbiology, 6(9), pp. 1037-1047. (doi: 10.2217/fmb.11.88) (PMID:21958143)
Wang, D. et al. (2011) Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds. Journal of Biological Chemistry, 286(34), pp. 29922-29931. (doi: 10.1074/jbc.M111.233858) (PMID:21724850) (PMCID:PMC3191033)
Burchmore, R. (2011) Animal parasitology and proteomics. In: Eckersall, P. D. and Whitfield, P. D. (eds.) Methods in Animal Proteomics. Wiley-Blackwell: Chichester, pp. 349-367. ISBN 9780813817910 (doi: 10.1002/9780470960660.ch12)
Kantawong, F., Robertson, M.E., Gadegaard, N. , Oreffo, R.O.C., Burchmore, R.J. and Dalby, M.J. (2011) Protein expression of STRO-1 cells in response to different topographic features. Journal of Tissue Engineering, 2011, 534603. (doi: 10.4061/2011/534603) (PMID:21772957) (PMCID:PMC3136090)
Gerou-Ferriani, M., McBrearty, A.R., Burchmore, R.J. , Jayawardena, K.G.I., Eckersall, P.D. and Morris, J.S. (2011) Agarose gel serum protein electrophoresis in cats with and without lymphoma and preliminary results of tandem mass fingerprinting analysis. Veterinary Clinical Pathology, 40(2), pp. 159-173. (doi: 10.1111/j.1939-165X.2011.00310.x)
Ward, C.P., Wong, P.E., Burchmore, R.J.S. , De Koning, H.P. and Barrett, M.P. (2011) Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns. Antimicrobial Agents and Chemotherapy, 55(5), pp. 2352-2361. (doi: 10.1128/AAC.01551-10)
2010
Naula, C.M. , Logan, F.M., Wong, P.E., Barrett, M.P. and Burchmore, R.J. (2010) A glucose transporter can mediate ribose uptake: definition of residues that confer substrate specificity in a sugar transporter. Journal of Biological Chemistry, 285(39), pp. 29721-29728. (doi: 10.1074/jbc.M110.106815)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)
Murphy, L., Eckersall, P.D., Bishop, S.C., Pettit, J.J., Huntley, J.F., Burchmore, R.J.S. and Stear, M.J. (2010) Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta. Parasitology, 137(8), pp. 1249-1260. (doi: 10.1017/S0031182010000028)
Szoor, B., Ruberto, I., Burchmore, R.J.S. and Matthews, K.R. (2010) A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway. Genes and Development, 24(12), pp. 1306-1316. (doi: 10.1101/gad.570310)
Burchmore, R.J.S. (2010) Neuroproteomics. Expert Review of Proteomics, 7(3), pp. 331-332. (doi: 10.1586/epr.10.17)
Henriquez, F.L., Campbell, S.A., Roberts, C.W., Mullen, A.B., Burchmore, R. and Carter, K.C. (2010) Vaccination with recombinant Leishmania donovani gamma-glutamylcysteine synthetase fusion protein protects against L. donovani infection. Journal of Parasitology, 96(5), pp. 929-936. (doi: 10.1645/ge-2360.1) (PMID:20950100)
McNamara, L.E., Dalby, M.J., Riehle, M.O. and Burchmore, R.J.S. (2010) Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications. Journal of the Royal Society: Interface, 7(Sppl 1), S107-S118. (doi: 10.1098/rsif.2009.0177.focus)
Stewart, M.L. et al. (2010) Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes. Eukaryotic Cell, 9(2), pp. 336-343. (doi: 10.1128/EC.00200-09) (PMID:19966032) (PMCID:PMC2823006)
Vincent, I., Scotcher, J. and Burchmore, R. (2010) Sixth exploratory measurement science group symposium. Expert Review of Proteomics, 7(1), pp. 19-20. (doi: 10.1586/epr.09.88)
Romero, I. C., Mehaffy, C., Burchmore, R. J. , Dobos-Elder, K., Brennan, P. and Walker, J. (2010) Identification of promoter-binding proteins of the fbp A and C genes in Mycobacterium tuberculosis. Tuberculosis, 90(1), pp. 25-30. (doi: 10.1016/j.tube.2009.10.001)
Luu, V., Brems, S., Hoheisel, J.D., Burchmore, R. , Guilbride, D.L. and Clayton, C. (2010) Corrigendum to "Functional analysis of Trypanosoma brucei PUF1" [Mol. Biochem. Parasitol. 150 (2006) 340–349]. Molecular and Biochemical Parasitology, 169(1), p. 70. (doi: 10.1016/j.molbiopara.2009.09.003)
Daneshevar, H., Molaei, M. M., Kamiabi, H., Burchmore, R.J.S. , Hagan, P. and Phillips, R.S. (2010) Gentamicin-attenuated Leishmania infantum: cellular immunity production and protection of dogs against experimental canine leishmaniasis. Parasite Immunology, 32(11-12), pp. 722-730. (doi: 10.1111/j.1365-3024.2010.01237.x)
Mutapi, F., Bourke, C., Harcus, Y., Midzi, N., Mduluza, T., Turner, C.M.R., Burchmore, R.J.S. and Maizels, R.M. (2010) Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4. Parasite Immunology, 33(3), pp. 181-192. (doi: 10.1111/j.1365-3024.2010.01270.x)
Vincent, I.M. , Creek, D., Watson, D.G., Kamleh, M.A., Woods, D.J., Wong, P.E., Burchmore, R.J.S. and Barrett, M.P. (2010) A molecular mechanism for eflornithine resistance in African trypanosomes. PLoS Pathogens, 6(11), e1001204. (doi: 10.1371/journal.ppat.1001204) (PMID:21124824) (PMCID:PMC2991269)
Ward, C. P., Burgess, K. E.V., Burchmore, R.J.S. , Barrett, M.P. and De Koning, H.P. (2010) A fluorescence-based assay for the uptake of CPD0801 (DB829) by African trypanosomes. Molecular and Biochemical Parasitology, 174(2), pp. 145-149. (doi: 10.1016/j.molbiopara.2010.07.002)
2009
Kantawong, F., Burchmore, R.J.S. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Proteomic analysis of human osteoprogenitor response to disordered nanotopography. Journal of the Royal Society: Interface, (doi: 10.1098/rsif.2008.0447)
Ataei, S., Burchmore, R. , Hodgson, J. C., Finucane, A., Parton, R. and Coote, J. G. (2009) Identification of immunogenic proteins associated with protection against haemorrhagic septicaemia after vaccination of calves with a live-attenuated aroA derivative of Pasteurella multocida B:2. Research in Veterinary Science, 87(2), pp. 207-210. (doi: 10.1016/j.rvsc.2009.01.007)
Daneshvar, H., Burchmore, R., Hagan, P. and Phillips, R. S. (2009) Leishmania major H-line attenuated under pressure of gentamicin, induces a Th1 response which protects susceptible BALB/c mice against infection with virulent L. major. Parasitology, 136(11), pp. 1243-1250. (doi: 10.1017/S0031182009990679)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)
Rossi, L., Riehle, M.O. , McNamara, L.E., Burchmore, R. , Dalby, M.J. , McMurray, R.J., Gadegaard, N. , Ahmed, S. and Tsimbouri, P.M. (2009) Research highlights. Nanomedicine, 4(6), pp. 613-617. (doi: 10.2217/nnm.09.46)
Kantawong, F., Burchmore, R.J.S., Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2009) Differential in-gel electrophoresis (DIGE) analysis of human bone marrow osteoprogenitor cell contact guidance. Acta Biomaterialia, 5(4), pp. 1137-1146. (doi: 10.1016/j.actbio.2008.11.001)
Daneshvar, H., Molaei, M.M., Afshar, R.M., Kamiabi, H., Burchmore, R.J.S. , Hagan, P. and Phillips, R.S. (2009) Gentamicin-attenuated Leishmania infantum: A clinicopathological study in dogs. Veterinary Immunology and Immunopathology, 129(1-2), pp. 28-35. (doi: 10.1016/j.vetimm.2008.12.002)
2008
Dalby, M.J. , McNamara, L.E., Riehle, M.O. , Burchmore, R.J.S. , Kuntanawat, P., McMurray, R.J., Gadegaard, N. and Andar, A. (2008) Research highlights. Nanomedicine, 3(4), pp. 411-414. (doi: 10.2217/17435889.3.4.411)
Mutapi, F., Burchmore, R. , Mduluza, T., Midzi, N., Turner, C. M. R. and Maizels, R. M. (2008) Age‐related and infection intensity–related shifts in antibody recognition of defined protein antigens in a schistosome‐exposed population. Journal of Infectious Diseases, 198(2), pp. 167-175. (doi: 10.1086/589511)
Kamleh, A., Barrett, M.P. , Wildridge, D., Burchmore, R.J.S. , Scheltema, R.A.. and Watson, D.G. (2008) Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules. Rapid Communications in Mass Spectrometry, 22(12), pp. 1912-1918. (doi: 10.1002/rcm.3564)
Bridges, D.J., Pitt, A.R., Hanrahan, O., Brennan, K., Voorheis, H.P., Herzyk, P. , de Koning, H.P. and Burchmore, R.J.S. (2008) Characterisation of the plasma membrane subproteome of bloodstream form Trypanosoma brucei. Proteomics, 8(1), pp. 83-99. (doi: 10.1002/pmic.200700607)
2007
Bridges, D. J., Gould, M. K., Nerima, B., Maser, P., Burchmore, R. J. S. and de Koning, H. P. (2007) Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes. Molecular Pharmacology, 71, pp. 1098-1108. (doi: 10.1124/mol.106.031351)
Kantawong, F., Dalby, M. and Burchmore, R. (2007) Differential proteomics evaluation of osteoprogenitor growth on microgrooved surfaces using bioreactor culture. Comparative Biochemistry and Physiology. Part A: Molecular and Integrative Physiology, 146(4), S192. (doi: 10.1016/j.cbpa.2007.01.420)
Hannigan, A., Burchmore, R. and Wilson, J. (2007) The optimization of Protocols for Proteome difference gel electrophoresis (DiGE) analysis of Preneoplastic skin. Journal of Proteome Research, 6, pp. 3422-3432. (doi: 10.1021/pr0606878)
Naula, C. , Alibu, V., Brock, J., Veitch, N.J. , Burchmore, R.J.S. and Barrett, M. (2007) A new erythrose 4-phosphate dehydrogenase coupled assay for transketolase. Journal of Biochemical and Biophysical Methods, 70(6), pp. 1185-1187. (doi: 10.1016/j.jprot.2007.11.002)
Nelson, M.M., Jones, A.R., Carmen, J.C., Sinai, A.P.,, Burchmore, R. and Wastling, J.M. (2007) Modulation of the host cell proteome by the intracellular apicomplexan parasite Toxoplasma gondii. Infection and Immunity, 76(2), pp. 828-844. (doi: 10.1128/IAI.01115-07)
2006
Luu, V.D., Brems, S., Hoheisel, J.D., Burchmore, R. , Guilbride, D.L. and Clayton, C. (2006) Functional analysis of Trypanosoma brucei PUF1. Molecular and Biochemical Parasitology, 150(2), pp. 340-349. (doi: 10.1016/j.molbiopara.2006.09.007)
Burchmore, R. (2006) Identification of anti-infective targets through comparative proteomics. Expert Review of Anti-Infective Therapy, 4(2), pp. 163-165. (doi: 10.1586/14787210.4.2.163)
Walker, J., Vasquez, J., Gomez, M., Drummelsmith, J., Burchmore, R. , Girard, I. and Ouellette, M. (2006) Identification of developmentally-regulated proteins in Leishmania panamensis promastigotes and by proteome profiling of axenic amastigotes. Molecular and Biochemical Parasitology, 147, pp. 64-73. (doi: 10.1016/j.molbiopara.2006.01.008)
2005
De Koning, H. P. , Bridges, D. J. and Burchmore, R. J. S. (2005) Purine and pyrimidine transport in pathogenic protozoa: From biology to therapy. FEMS Microbiology Reviews, 29(5), pp. 987-1020. (doi: 10.1016/j.femsre.2005.03.004)
Mutapi, F., Burchmore, R., Mduluza, T., Foucher, A., Harcus, Y., Nicoll, G., Midzi, N., Turner, C. and Maizels, R. (2005) Praziquantel treatment of individuals exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens. Journal of Infectious Diseases, 192(6), pp. 1108-1118. (doi: 10.1086/432553) (PMID:16107967)
Stewart, M., Krishna, S., Burchmore, R. , Brun, R., de Koning, H. , Boykin, D., Tidwell, R., Hall, J. and Barrett, M. (2005) Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test. Lancet, 366, pp. 486-487. (doi: 10.1016/S0140-6736(05)66793-1)
2004
de Koning, H. , Anderson, L., Stewart, M., Burchmore, R. , Wallace, L. and Barrett, M. (2004) The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in African trypanosomes. Antimicrobial Agents and Chemotherapy, 48, pp. 1515-1519. (doi: 10.1128/AAC.48.5.1515-1519.2004)
2003
Barrett, M. , Burchmore, R. , Stich, A., Lazzari, J., Frasch, A., Cazzulo, J. and Krishna, S. (2003) The trypanosomiases. Lancet, 362(9394), pp. 1469-1480. (doi: 10.1016/S0140-6736(03)14694-6)
Burchmore, R. (2003) A plethora of targets, a paucity of drugs: Progress towards the development of novel chemotherapies for human African trypanosomiasis. Expert Review of Anti-Infective Therapy, 1(1), pp. 157-165. (doi: 10.1586/14787210.1.1.157)
Burchmore, R. , Rodriguez-Contreras, D., McBride, K., Barrett, M. , Modi, G., Sacks, D. and Landfear, S. (2003) Genetic characterization of glucose transporter function in Leishmania mexicana. Proceedings of the National Academy of Sciences of the United States of America, 100(7), pp. 3901-3906. (doi: 10.1073/pnas.0630165100)
Burchmore, R. , Wallace, L., Candlish, D., Al-Salabi, M., Beal, P., Barrett, M. , Baldwin, S. and de Koning, H. (2003) Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan. Journal of Biological Chemistry, 278(26), pp. 23502-23507. (doi: 10.1074/jbc.M301252200)
Matovu, E. et al. (2003) Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei. Eukaryotic Cell, 2(5), pp. 1003-1008. (doi: 10.1128/EC.2.5.1003-1008.2003)
Maugeri, D., Cazzulo, J., Burchmore, R. , Barrett, M. and Ogbunude, P. (2003) Pentose phosphate metabolism in Leishmania mexicana. Molecular and Biochemical Parasitology, 130(2), pp. 117-125. (doi: 10.1016/S0166-6851(03)00173-7)
2002
Leslie, G., Barrett, M. and Burchmore, R. (2002) Leishmania mexicana: promastigotes migrate through osmotic gradients. Experimental Parasitology, 102(2), pp. 117-120. (doi: 10.1016/S0014-4894(03)00031-6)
Burchmore, R. , Ogbunude, P., Enanga, B. and Barrett, M. (2002) Chemotherapy of human African trypanosomiasis. Current Pharmaceutical Design, 8(4), pp. 257-267. (doi: 10.2174/1381612023396159)
Enanga, B., Burchmore, R. , Stewart, M. and Barrett, M. (2002) Sleeping sickness and the brain. Cellular and Molecular Life Sciences, 59(5), pp. 845-858. (doi: 10.1007/s00018-002-8472-0)
2001
Burchmore, R. , Turner, C. M. R. and Janssen, C. S. (2001) After the genome-where next? Molecular and Biochemical Parasitology, 118(2), pp. 129-131. (doi: 10.1016/S0166-6851(01)00364-4) (PMID:11738702)
Burchmore, R. and Barrett, M. (2001) Life in vacuoles - nutrient acquisition by Leishmania amastigotes. International Journal for Parasitology, 31(12), pp. 1311-1320. (doi: 10.1016/S0020-7519(01)00259-4)
2000
Krishna, S., Woodrow, C.J., Burchmore, R.J.S. , Saliba, K.J. and Kirk, K. (2000) Hexose transport in asexual stages of Plasmodium falciparum and Kinetoplastidae. Parasitology Today, 16(12), pp. 516-521. (doi: 10.1016/s0169-4758(00)01762-2) (PMID:11121848)
Woodrow, C.J., Burchmore, R.J. and Krishna, S. (2000) Hexose permeation pathways in Plasmodium falciparum-infected erythrocytes. Proceedings of the National Academy of Sciences of the United States of America, 97(18), pp. 9931-9936. (doi: 10.1073/pnas.170153097) (PMID:10954735) (PMCID:PMC27630)
1998
Burchmore, R.J.S. and Landfear, S.M. (1998) Differential regulation of multiple glucose transporter genes in Leishmania mexicana. Journal of Biological Chemistry, 273, pp. 29118-29126. (doi: 10.1074/jbc.273.44.29118) (PMID:9786920)
1995
Burchmore, R.J.S. and Hart, D.T. (1995) Glucose transport in amastigotes and promastigotes of Leishmania mexicana mexicana. Molecular and Biochemical Parasitology, 74(1), pp. 77-86. (doi: 10.1016/0166-6851(95)02485-9) (PMID:8719247)
1994
Langford, C.K., Burchmore, R.J.S. , Hart, D.T., Wagner, W. and Landfear, S.M. (1994) Biochemistry and molecular genetics of Leishmania glucose transporters. Parasitology, 108(S1), S73-S83. (doi: 10.1017/s0031182000075740) (PMID:8084658)
Articles
Girasol, M. J. et al. (2023) RAD51-mediated R-loop formation acts to repair transcription associated DNA breaks driving antigenic variation in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America, 120(48), e230930612. (doi: 10.1073/pnas.2309306120) (PMID:37988471) (PMCID:PMC10691351)
Huang, Y., Jonsson, N. N. , McLaughlin, M. , Burchmore, R. , Johnson, P. C.D. , Jones, R. , McGill, S., Brady, N., Weidt, S. and Eckersall, D. (2023) Quantitative TMT-based proteomics revealing host, dietary and microbial proteins in bovine faeces including barley serpin Z4, a prominent component in the head of beer. Journal of Proteomics, 285, 104941. (doi: 10.1016/j.jprot.2023.104941) (PMID:37285906)
Kuleš, J., Rubić, I., Farkaš, V., Barić Rafaj, R., Gotić, J., Crnogaj, M., Burchmore, R. , Eckersall, D. , Mrljak, V. and Leisewitz, A. L. (2023) Serum proteome profiling of naturally acquired Babesia rossi infection in dogs. Scientific Reports, 13, 10249. (doi: 10.1038/s41598-023-37312-9) (PMID:37353646) (PMCID:PMC10290096)
Ungogo, M. A. et al. (2023) Cloning and characterization of Trypanosoma congolense and T. vivax nucleoside transporters reveal the potential of P1-type carriers for the discovery of broad-spectrum nucleoside-based therapeutics against Animal African Trypanosomiasis. International Journal of Molecular Sciences, 24(4), 3144. (doi: 10.3390/ijms24043144) (PMID:36834557) (PMCID:PMC9960827)
Nguyen, T. X. et al. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part I: serum proteomes. Journal of Proteomics, 270, 104740. (doi: 10.1016/j.jprot.2022.104740) (PMID:36191802)
Nguyen, T. X., Agazzo, A., McGill, S., Weidt, S., Han, Q. H., Gelemanović, A., McLaughlin, M. , Savoini, G., Eckersall, P. D. and Burchmore, R. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part II: ileum proteomes. Journal of Proteomics, 270, 104739. (doi: 10.1016/j.jprot.2022.104739) (PMID:36174954)
Anuntasomboon, P., Siripattanapipong, S., Unajak, S., Choowongkomon, K., Burchmore, R. , Leelayoova, S., Mungthin, M. and E-kobon, T. (2022) Identification of a conserved maxicircle and unique minicircles as part of the mitochondrial genome of Leishmania martiniquensis strain PCM3 in Thailand. Parasites and Vectors, 15, 459. (doi: 10.1186/s13071-022-05592-1) (PMID:36510327) (PMCID:PMC9743726)
Alpizar-Sosa, E. A. et al. (2022) Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLoS Neglected Tropical Diseases, 16(9), e0010779. (doi: 10.1371/journal.pntd.0010779) (PMID:36170238) (PMCID:PMC9581426)
Anuntasomboon, P., Siripattanapipong, S., Unajak, S., Choowongkomon, K., Burchmore, R. , Leelayoova, S., Mungthin, M. and E-kobon, T. (2022) Making the most of its short reads: a bioinformatics workflow for analysing the short-read-only data of Leishmania orientalis (formerly named Leishmania siamensis) isolate PCM2 in Thailand. Biology, 11(9), 1272. (doi: 10.3390/biology11091272) (PMID:36138751) (PMCID:PMC9495971)
Díaz, M. L., Burgess, K., Burchmore, R. , Gómez, M. A., Gómez-Ochoa, S. A., Echeverría, L. E., Morillo, C. and González, C. I. (2022) Metabolomic profiling of end-stage heart failure secondary to chronic Chagas cardiomyopathy. International Journal of Molecular Sciences, 23(18), 10456. (doi: 10.3390/ijms231810456) (PMID:36142367) (PMCID:PMC9499603)
Aldfer, M. M. , AlSiari, T. A., Elati, H. A.A. , Natto, M. J., Alfayez, I. A., Campagnaro, G. D., Sani, B., Burchmore, R. J. S. , Diallinas, G. and De Koning, H. (2022) Nucleoside transport and nucleobase uptake null mutants in Leishmania mexicana for the routine expression and characterization of purine and pyrimidine transporters. International Journal of Molecular Sciences, 23(15), 8139. (doi: 10.3390/ijms23158139) (PMID:35897714) (PMCID:PMC9331716)
Huang, Y., Burchmore, R. , Jonsson, N. N. , Johnson, P. C.D. and Eckersall, P. D. (2022) Technical report: In-gel sample preparation prior to proteomic analysis of bovine faeces increases protein identifications by removal of high molecular weight glycoproteins. Journal of Proteomics, 261, 104573. (doi: 10.1016/j.jprot.2022.104573) (PMID:35351658)
Nguyen, T. X. et al. (2022) Abundance of plasma proteins in response to divergent ratios of dietary ω6:ω3 fatty acids in gestating and lactating sows using a quantitative proteomics approach. Journal of Proteomics, 260, 104562. (doi: 10.1016/j.jprot.2022.104562) (PMID:35314360)
Hulme, H. et al. (2022) Mapping the influence of the gut microbiota on small molecules across the microbiome gut brain axis. Journal of the American Society for Mass Spectrometry, 33(4), pp. 649-659. (doi: 10.1021/jasms.1c00298) (PMID:35262356) (PMCID:PMC9047441)
Anuntasomboon, P., Siripattanapipong, S., Unajak, S., Choowongkomon, K., Burchmore, R. , Leelayoova, S., Mungthin, M. and E-kobon, T. (2022) Comparative draft genomes of Leishmania orientalis isolate PCM2 (formerly named Leishmania siamensis ) and Leishmania martiniquensis isolate PCM3 from the southern province of Thailand. Biology and Environment: Proceedings of the Royal Irish Academy, 11(4), e515. (doi: 10.3390/biology11040515) (PMID:35453714) (PMCID:PMC9031872)
Meewan, J. et al. (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14(2), e439. (doi: 10.3390/pharmaceutics14020439) (PMID:35214171) (PMCID:PMC8877401)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
McGill, S., Burchmore, R. J.S. , Pomeroy, P. P. and Kennedy, M. W. (2022) Is a little enough? Paucity of immune proteins in serum of precocial neonates of a marine carnivoran—the Atlantic grey seal. Frontiers in Ecology and Evolution, 9, 802510. (doi: 10.3389/fevo.2021.802510)
Fernández, D., Segura, C., Arman, M., McGill, S., Burchmore, R. and Lopera-Mesa, T. (2022) Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets. Clinical Proteomics, 19(1), 1. (doi: 10.1186/s12014-021-09337-7) (PMID:34991449) (PMCID:PMC8903537)
McGill, S., Burchmore, R. J. S. , Pomeroy, P. P. and Kennedy, M. W. (2022) Mirror image serum lipid carrier protein profiles in pup and lactating mother Atlantic grey seals reflect contrasting resource mobilisation challenges. Frontiers in Marine Science, 9, 944214. (doi: 10.3389/fmars.2022.944214)
Orrapin, S., Roytrakul, S., Phaonakrop, N., Thaisakun, S., Tragoolpua, K., Intorasoot, A., McGill, S., Burchmore, R. and Intorasoot, S. (2021) Fungicidal activity of recombinant javanicin against Cryptococcus neoformans is associated with intracellular target(s) involved in carbohydrate and energy metabolic processes. Molecules, 26(22), 7011. (doi: 10.3390/molecules26227011)
Nguyen, T. X., Agazzi, A., Comi, M., Bontempo, V., Guido, I., Panseri, S., Sauerwein, H., Eckersall, P. D. , Burchmore, R. and Savoini, G. (2020) Effects of low ω6:ω3 ratio in sow diet and seaweed supplement in piglet diet on performance, colostrum and milk fatty acid profiles, and oxidative status. Animals, 10(11), 2049. (doi: 10.3390/ani10112049) (PMID:33167599) (PMCID:PMC7694489)
Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)
Varjak, M. , Gestuveo, R. J., Burchmore, R. , Schnettler, E. and Kohl, A. (2020) aBravo is a novel Aedes aegypti antiviral protein that interacts with, but acts independently of, the exogenous siRNA pathway effector Dicer 2. Viruses, 12(7), 748. (doi: 10.3390/v12070748)
Damianou, A., Burge, R. J., Catta-Preta, C. M.C., Geoghegan, V., Nievas, Y. R., Newling, K., Brown, E., Burchmore, R. , Rodenko, B. and Mottram, J. C. (2020) Essential roles for deubiquitination in Leishmania life cycle progression. PLoS Pathogens, 16(6), e1008455. (doi: 10.1371/journal.ppat.1008455) (PMID:32544189) (PMCID:PMC7319358)
Royle, J. , Ramírez-Santana, C., Akpunarlieva, S., Donald, C. L. , Gestuveo, R. J., Anaya, J.-M., Merits, A., Burchmore, R. , Kohl, A. and Varjak, M. (2020) Glucose-regulated protein 78 interacts with Zika virus envelope protein and contributes to a productive infection. Viruses, 12(5), 524. (doi: 10.3390/v12050524)
Hulme, H. et al. (2020) Microbiome-derived carnitine mimics as novel mediators of gut-brain axis communication. Science Advances, 6(11), eaax6328. (doi: 10.1126/sciadv.aax6328) (PMID:32195337) (PMCID:PMC7065903)
Vargas, D. A., Prieto, M. D., Martínez-Valencia, A. J., Cossio, A., Burgess, K. E.V., Burchmore, R. J.S. and Gómez, M. A. (2019) Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis. Frontiers in Pharmacology, 10, 657. (doi: 10.3389/fphar.2019.00657) (PMID:31281253) (PMCID:PMC6595045)
Johnston, K., Kim, D.-H., Kerkhoven, E. J., Burchmore, R. , Barrett, M. P. and Achcar, F. (2019) Mapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U-13C-labelled substrates and LC-MS. Bioscience Reports, 39(5), BSR2018160. (doi: 10.1042/BSR20181601) (PMID:31028136) (PMCID:PMC6522824)
Ormsby, M. J., Grahame, E., Burchmore, R. and Davies, R. L. (2019) Comparative bioinformatic and proteomic approaches to evaluate the outer membrane proteome of the fish pathogen Yersinia ruckeri. Journal of Proteomics, 199, pp. 135-147. (doi: 10.1016/j.jprot.2019.02.014) (PMID:30831250) (PMCID:PMC6447952)
Acosta, H., Burchmore, R. , Naula, C. , Gualdrón-López, M., Quintero-Troconis, E., Cáceres, A. J., Michels, P. A.M., Concepción, J. L. and Quiñones, W. (2019) Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes. Molecular and Biochemical Parasitology, 229, pp. 62-74. (doi: 10.1016/j.molbiopara.2019.02.008) (PMID:30831156) (PMCID:PMC7082770)
McCanney, G. A., Mcgrath, M. A., Otto, T. D. , Burchmore, R. , Yates, E. A., Bavington, C. D., Willison, H. J. , Turnbull, J. E. and Barnett, S. C. (2019) Low sulfated heparins target multiple proteins for central nervous system repair. Glia, 67(4), pp. 668-687. (doi: 10.1002/glia.23562) (PMID:30585359)
Keuss, M. J., Hjerpe, R., Hsia, O., Gourlay, R., Burchmore, R. , Trost, M. and Kurz, T. (2019) Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death. EMBO Journal, 38, e100024. (doi: 10.15252/embj.2018100024) (PMID:30804002) (PMCID:PMC6418418)
Kaab, H., Bain, M. M. , Bartley, K., Turnbull, F. , Wright, H. W., Nisbet, A. J., Burchmore, R. and Eckersall, P. D. (2019) Serum and acute phase protein changes in laying hens, infested with poultry red mite. Poultry Science, 98(2), pp. 679-687. (doi: 10.3382/ps/pey431) (PMID:30239853)
Prakash, A. S., Kabli, A. M.F., Bulleid, N. and Burchmore, R. (2018) Mix-and-match proteomics: using advanced iodoacetyl tandem mass tag multiplexing to investigate cysteine oxidation changes with respect to protein expression. Analytical Chemistry, 90(24), pp. 14173-14180. (doi: 10.1021/acs.analchem.8b02517) (PMID:30452864)
Morlon-Guyot, J., El Hajj, H., Martin, K., Fois, A., Carrillo, A., Berry, L., Burchmore, R. , Meissner, M. , Lebrun, M. and Daher, W. (2018) A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis. Cellular Microbiology, 20(11), e12870. (doi: 10.1111/cmi.12870) (PMID:29911335)
Santana, A. M., Silva, D. G.,, Thomas, F. C., Bernardes, P. A., Pizauro, L. J.L., Santana, C. H., Burchmore, R. J.S. , Eckersall, P. D. and Fagliari, J. J. (2018) Blood serum acute phase proteins and iron dynamics during acute phase response of Salmonella enterica serotype Dublin experimentally infected buffalo calves. Veterinary Immunology and Immunopathology, 203, pp. 30-39. (doi: 10.1016/j.vetimm.2018.07.014) (PMID:30243370)
De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)
Santana, A. M., Thomas, F. C., Silva, D. G., McCulloch, E., Vidal, A. M.C., Burchmore, R. J.S. , Fagliari, J. J. and Eckersall, P. D. (2018) Reference 1D and 2D electrophoresis maps for potential disease related proteins in milk whey from lactating buffaloes and blood serum from buffalo calves (Water buffalo, Bubalus bubalis). Research in Veterinary Science, 118, pp. 449-465. (doi: 10.1016/j.rvsc.2018.04.010) (PMID:29734122)
Bilić, P., Guillemin, N., Kovačević, A., Ljubić, B. B., Jović, I., Galan, A., Eckersall, P. D. , Burchmore, R. and Mrljak, V. (2018) Serum proteome profiling in canine idiopathic dilated cardiomyopathy using TMT-based quantitative proteomics approach. Journal of Proteomics, 179, pp. 110-121. (doi: 10.1016/j.jprot.2018.03.007) (PMID:29530679)
Kovarova, J., Pountain, A. W. , Wildridge, D., Weidt, S., Bringaud, F., Burchmore, R. J.S. , Achcar, F. and Barrett, M. P. (2018) Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana. PLoS Pathogens, 14(3), e1006953. (doi: 10.1371/journal.ppat.1006953) (PMID:29554142) (PMCID:PMC5882173)
Nayak, A., Akpunarlieva, S., Barrett, M. and Burchmore, R. (2018) A defined medium for Leishmania culture allows definition of essential amino acids. Experimental Parasitology, 185, pp. 39-52. (doi: 10.1016/j.exppara.2018.01.009) (PMID:29326050)
Williams, J. J.L., Al-Otaiq, N., Mullen, W. , Burchmore, R. , Liu, L., Baillie, G. S. , Schaper, F., Pilch, P. F. and Palmer, T. M. (2018) Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability. Nature Communications, 9, 168. (doi: 10.1038/s41467-017-02585-y) (PMID:29330478) (PMCID:PMC5766592)
Ferrazza, R. d. A., Dos Santos Schmidt, E. M., Mihm Carmichael, M., de Souza, F. F., Burchmore, R. , Sartori, R., Eckersall, P. D. and Ferreira, J. C. P. (2018) Quantitative proteomic profiling of bovine follicular fluid during follicle development. Biology of Reproduction, 97(6), pp. 835-849. (doi: 10.1093/biolre/iox148) (PMID:29149247)
Akpunarlieva, S. and Burchmore, R. (2017) The role of membrane transporters in Leishmania virulence. Emerging Topics in Life Sciences, 1(6), pp. 601-611. (doi: 10.1042/etls20170119)
Lowe, A. D., Bawazeer, S., Watson, D. G., McGill, S., Burchmore, R. J.S. , Pomeroy, P.P. (P.) and Kennedy, M. W. (2017) Rapid changes in Atlantic grey seal milk from birth to weaning – immune factors and indicators of metabolic strain. Scientific Reports, 7, 16093. (doi: 10.1038/s41598-017-16187-7) (PMID:29170469) (PMCID:PMC5700954)
Martinez-Subiela, S., Horvatic, A., Escribano, D., Pardo-Marin, L., Kocaturk, M., Mrljak, V., Burchmore, R. , Ceron, J. J. and Yilmaz, Z. (2017) Identification of novel biomarkers for treatment monitoring in canine leishmaniosis by high-resolution quantitative proteomic analysis. Veterinary Immunology and Immunopathology, 191, pp. 60-67. (doi: 10.1016/j.vetimm.2017.08.004) (PMID:28895868)
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Rojas, F., Koszela, J., Búa, J., Llorente, B., Burchmore, R. , Auer, M., Mottram, J. C. and Téllez-Iñón, M. T. (2017) The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei. PLoS Neglected Tropical Diseases, 11(6), e0005626. (doi: 10.1371/journal.pntd.0005626) (PMID:28609481) (PMCID:PMC5507466)
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O'Reilly, E. L., Burchmore, R. J. , Sparks, N. H. and Eckersall, P. D. (2017) The effect of microbial challenge on the intestinal proteome of broiler chickens. Proteome Science, 15, 10. (doi: 10.1186/s12953-017-0118-0) (PMID:28572745) (PMCID:PMC5450085)
Schrama, D., Richard, N., Silva, T. S., Figueiredo, F. A., Conceição, L. E.C., Burchmore, R. , Eckersall, D. and Rodrigues, P. M.L. (2017) Enhanced dietary formulation to mitigate winter thermal stress in gilthead sea bream (Sparus aurata): a 2D-DIGE plasma proteome study. Fish Physiology and Biochemistry, 43(2), pp. 603-617. (doi: 10.1007/s10695-016-0315-2) (PMID:27882445)
Marcos-López, M., Rodger, H. D., O'Connor, I., Braceland, M., Burchmore, R. J.S. , Eckersall, P. and MacCarthy, E. (2017) A proteomic approach to assess the host response in gills of farmed Atlantic salmon Salmo salar L. affected by amoebic gill disease. Aquaculture, 470, pp. 1-10. (doi: 10.1016/j.aquaculture.2016.12.009)
Lindeberg, H., Burchmore, R. J.S. and Kennedy, M. W. (2017) Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation. Royal Society Open Science, 4(3), 161085. (doi: 10.1098/rsos.161085) (PMID:28405395) (PMCID:PMC5383852)
Akpunarlieva, S., Weidt, S., Lamasudin, D., Naula, C. , Henderson, D., Barrett, M. , Burgess, K. and Burchmore, R. (2017) Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania. Journal of Proteomics, 155, pp. 85-98. (doi: 10.1016/j.jprot.2016.12.009) (PMID:28040509)
Lobo-Rojas, Á. E., González-Marcano, E. B., Valera-Vera, E. A., Acosta, H. R., Quiñones, W. A., Burchmore, R. J.S. , Concepción, J. L. and Cáceres, A. J. (2016) Trypanosoma cruzi contains two galactokinases; molecular and biochemical characterization. Parasitology International, 65(5 Pt A), pp. 472-482. (doi: 10.1016/j.parint.2016.06.008) (PMID:27312997)
Ormsby, M. J., Caws, T., Burchmore, R. , Wallis, T., Verner-Jeffreys, D. W. and Davies, R. L. (2016) Yersinia ruckeri isolates recovered from diseased Atlantic Salmon (Salmo salar) in Scotland are more diverse than those from Rainbow Trout (Oncorhynchus mykiss) and represent distinct subpopulations. Applied and Environmental Microbiology, 82(19), pp. 5785-5794. (doi: 10.1128/aem.01173-16) (PMID:27451448) (PMCID:PMC5038039)
Mudaliar, M. et al. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. Molecular BioSystems, 12(9), pp. 2748-2761. (doi: 10.1039/C6MB00290K) (PMID:27412694) (PMCID:PMC5048399)
Thomas, F., Mudaliar, M. , Tassi, R., Mcneilly, T., Burchmore, R. , Burgess, K., Herzyk, P. , Zadoks, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics. Molecular BioSystems, 12(9), pp. 2762-2769. (doi: 10.1039/C6MB00289G) (PMID:27412568)
Thomas, F., Mullen, W. , Tassi, R., Ramírez-Torres, A., Mudaliar, M. , Mcneilly, T., Zadoks, R. , Burchmore, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics. Molecular BioSystems, 12(9), pp. 2735-2747. (doi: 10.1039/C6MB00239K) (PMID:27412456) (PMCID:PMC5048397)
Tsiropoulou, S., Montezano, A., Scott, A., Burchmore, R.J. and Touyz, R.M. (2016) PS 07-14 vascular protein oxidation and redox proteomics in hypertension. Journal of Hypertension, 34, e287. (doi: 10.1097/01.hjh.0000500678.85921.bc)
Grewal, J. S. et al. (2016) PNT1 is a C11 cysteine peptidase essential for replication of the trypanosome kinetoplast. Journal of Biological Chemistry, 291, pp. 9492-9500. (doi: 10.1074/jbc.M116.714972) (PMID:26940875) (PMCID:PMC4850289)
Tsiropoulou, S., Montezano, A.C., Scott, A., Burchmore, R.J. and Touyz, R. (2015) 41 Vascular protein oxidation and redox proteomics in human hypertension. Heart, 101(Suppl), A13-A14. (doi: 10.1136/heartjnl-2015-308734.41)
Griffiths, K., Rong, H., Wang, H., Zhang, Z., Zhang, T., Watson, D. G., Burchmore, R. , Loeffler, I.K. and Kennedy, M. (2015) Prolonged transition time between colostrum and mature milk in a bear, the giant panda, Ailuropoda melanoleuca. Royal Society Open Science, 2, 150395. (doi: 10.1098/rsos.150395)
Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)
Hajjaran, H., Mohammadi Bazargani, M., Mohebali, M., Burchmore, R. , Hosseini Salekdeh, G., Kazemi-Rad, E. and Khoramizadeh, M. (2015) Comparison of the proteome profiling of Iranian isolates of Leishmania tropica, L. major and L. infantum by two-dimensional electrophoresis (2-DE) and mass-spectrometry. Iranian Journal of Parasitology, 10(4), pp. 530-540. (PMID:26811718) (PMCID:PMC4724828)
Fyfe, C.D., Grinter, R., Josts, I., Mosbahi, K., Roszak, A.W., Cogdell, R.J. , Wall, D.M. , Burchmore, R.J.S. , Byron, O. and Walker, D. (2015) Structure of protease-cleaved escherichia coliα-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallographica. Section D: Biological Crystallography, 71(7), pp. 1478-1486. (doi: 10.1107/s1399004715008548) (PMID:26143919) (PMCID:PMC4498604)
Hajjaran, H., Mousavi, P., Burchmore, R. , Mohebali, M., Mohammadi Bazargani, M., Hosseini Salekdeh, G., Kazemi-Rad, E. and Khoramizadeh, M. R. (2015) Comparative proteomic profiling of Leishmania tropica: investigation of a case infected with simultaneous cutaneous and viscerotropic leishmaniasis by 2-dimentional electrophoresis and mass spectrometry. Iranian Journal of Parasitology, 10(3), pp. 366-380. (PMID:26622292) (PMCID:PMC4662737)
Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93(1), pp. 199-211. (doi: 10.1111/mmi.12651) (PMID:24846743) (PMCID:PMC4249723)
Shafie, I. N.F., McLaughlin, M. , Burchmore, R. , Lim, M. A. A., Montague, P., Johnston, P. E.J. , Penderis, J. and Anderson, T. J. (2014) The chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog. Cell Stress and Chaperones, 19(3), pp. 311-320. (doi: 10.1007/s12192-013-0457-4)
Daneshvar, H., Mahmmodi, Z., Kamiabi, H., Phillips, R. S. and Burchmore, R. (2014) Dogs vaccinated with gentamicin-attenuated Leishmania infantum or infected with wild-type parasite can be distinguished by Western blotting. Parasite Immunology, 36(5), pp. 218-224. (doi: 10.1111/pim.12108)
Kuleš, J., Mrljak, V., Rafaj, R., Selanec, J., Burchmore, R. and Eckersall, P. D. (2014) Identification of serum biomarkers in dogs naturally infected with Babesia canis canis using a proteomic approach. BMC Veterinary Research, 10(1), p. 111. (doi: 10.1186/1746-6148-10-111)
Daneshvar, H., Namazi, M. J., Kamiabi, H., Burchmore, R. , Cleaveland, S. and Phillips, S. (2014) Gentamicin-attenuated leishmania infantum vaccine: protection of dogs against canine visceral leishmaniosis in endemic area of southeast of Iran. PLoS Neglected Tropical Diseases, 8(4), e2757. (doi: 10.1371/journal.pntd.0002757) (PMID:24743691) (PMCID:PMC3990512)
Munday, J. C. et al. (2014) Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. Journal of Antimicrobial Chemotherapy, 69(3), pp. 651-663. (doi: 10.1093/jac/dkt442) (PMID:24235095) (PMCID:PMC3922157)
Ceciliani, F., Eckersall, D. , Burchmore, R. and Lecchi, C. (2014) Proteomics in veterinary medicine: applications and trends in disease pathogenesis and diagnostics. Veterinary Pathology, 51(2), pp. 351-362. (doi: 10.1177/0300985813502819)
Burchmore, R. (2014) Mapping pathways to drug resistance with proteomics. Expert Review of Proteomics, 11(1), pp. 1-3. (doi: 10.1586/14789450.2014.871497)
Kerkhoven, E. J. et al. (2013) Handling uncertainty in dynamic models: the pentose phosphate pathway in trypanosoma brucei. PLoS Computational Biology, 9(12), e1003371. (doi: 10.1371/journal.pcbi.1003371) (PMID:24339766) (PMCID:PMC3854711)
Millerioux, Y. et al. (2013) The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control. Molecular Microbiology, 90(1), pp. 114-129. (doi: 10.1111/mmi.12351) (PMID:23899193) (PMCID:PMC4034587)
Morrice, N. and Burchmore, R. (2013) Editorial. Journal of Proteomics, 88, pp. 1-3. (doi: 10.1016/j.jprot.2013.05.035)
Roncada, P., Stipetic, L.H., Bonizzi, L., Burchmore, R.J.S. and Kennedy, M.W. (2013) Proteomics as a tool to explore human milk in health and disease. Journal of Proteomics, 88, pp. 47-57. (doi: 10.1016/j.jprot.2013.04.008)
Rujeni, N., Nausch, N., Midzi, N., Cowan, G.J., Burchmore, R. , Cavanagh, D.R., Taylor, D.W., Mduluza, T. and Mutapi, F. (2013) Immunological consequences of antihelminthic treatment in preschool children exposed to urogenital schistosome infection. Journal of Tropical Medicine, 2013, 283619. (doi: 10.1155/2013/283619) (PMID:23840222) (PMCID:PMC3687481)
Atherton, M.J., Braceland, M., Fontaine, S. , Waterston, M.M., Burchmore, R.J. , Eadie, S., Eckersall, P.D. and Morris, J.S. (2013) Changes in the serum proteome of canine lymphoma identified by electrophoresis and mass spectrometry. Veterinary Journal, 196(3), pp. 320-324. (doi: 10.1016/j.tvjl.2012.12.010)
Atherton, M.J., Braceland, M., Harvie, J., Burchmore, R.J. , Eadie, S., Eckersall, P.D. and Morris, J.S. (2013) Characterisation of the normal canine serum proteome using a novel electrophoretic technique combined with mass spectrometry. Veterinary Journal, 196(3), pp. 315-319. (doi: 10.1016/j.tvjl.2012.12.011)
Feng, X., Rodriguez-Contreras, D., Polley, T., Lye, L.-F., Scott, D., Burchmore, R.J.S. , Beverley, S.M. and Landfear, S.M. (2013) 'Transient' genetic suppression facilitates generation of hexose transporter null mutants inLeishmania mexicana. Molecular Microbiology, 87(2), pp. 412-429. (doi: 10.1111/mmi.12106)
Bain, M.M. , McDade, K., Burchmore, R. , Law, A., Wilson, P.W., Schmutz, M., Preisinger, R. and Dunn, I.C. (2013) Enhancing the egg's natural defence against bacterial penetration by increasing cuticle deposition. Animal Genetics, 44(6), pp. 661-668. (doi: 10.1111/age.12071)
Monnerat, S., Almeida Costa, C.I., Forkert, A.C., Benz, C., Hamilton, A., Tetley, L., Burchmore, R. , Novo, C., Mottram, J.C. and Hammarton, T.C. (2013) Identification and functional characterisation of CRK12:CYC9, a novel cyclin-dependent kinase (CDK)-cyclin complex in Trypanosoma brucei. PLoS ONE, 8(6), e67327. (doi: 10.1371/journal.pone.0067327) (PMID:23805309) (PMCID:PMC3689728)
O'Reilly, E.L., Burchmore, R.J. , Eckersall, P.D. and Sparks, N.H.C. (2013) The effect of microbial challenge on the intestinal proteome of broiler chickens. British Poultry Abstracts, 9(1), pp. 5-6. (doi: 10.1080/17466202.2013.842677)
Burchmore, R. (2012) Parasites in the brain? The search for sleeping sickness biomarkers. Expert Review of Anti-Infective Therapy, 10(11), pp. 1283-1286. (doi: 10.1586/ERI.12.124)
Daneshvar, H., Sedghy, F., Dabiri, S., Kamiabi, H., Molaei, M.M., Phillips, S. and Burchmore, R. (2012) Alteration in mononuclear cell subpopulations in dogs immunized with gentamicin-attenuated Leishmania infantum. Parasitology, 139(13), pp. 1689-1696. (doi: 10.1017/S0031182012001187)
Burgess, K.E.V. and Burchmore, R.J.S. (2012) Strategies to dissect parasite proteomes. Parasitology, 139(9), pp. 1119-1130. (doi: 10.1017/S0031182011002368)
Ginger, M.L., McKean, P.G., Burchmore, R.J.S. and Grant, K.M. (2012) Proteomic insights into parasite biology. Parasitology, 139(9), pp. 1101-1102. (doi: 10.1017/S0031182012000947)
Walker, J., Gongora, R., Vasquez, J.J., Drummelsmith, J., Burchmore, R. , Roy, G., Ouellette, M., Gomez, M.A. and Saravia, N.G. (2012) Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis. Molecular and Biochemical Parasitology, 183(2), pp. 166-176. (doi: 10.1016/j.molbiopara.2012.03.002) (PMID:22449941)
E-komon, T., Burchmore, R. , Herzyk, P. and Davies, R. (2012) Predicting the outer membrane proteome of Pasteurella multocida based on consensus prediction enhanced by results integration and manual confirmation. BMC Bioinformatics, 13(1), 63. (doi: 10.1186/1471-2105-13-63) (PMID:22540951) (PMCID:PMC3403877)
McNamara, L.E., Burchmore, R.J.S. , Riehle, M.O. , Herzyk, P. , Biggs, M.J.P., Wilkinson, C.D.W., Curtis, A.S.G. and Dalby, M.J. (2012) The role of microtopography in cellular mechanotransduction. Biomaterials, 33(10), pp. 2835-2847. (doi: 10.1016/j.biomaterials.2011.11.047)
Daneshvar, H., Wyllie, S., Phillips, S., Hagan, P. and Burchmore, R. (2012) Comparative proteomics profiling of a gentamicin-attenuated Leishmania infantum cell line identifies key changes in parasite thiol-redox metabolism. Journal of Proteomics, 75(5), pp. 1463-1471. (doi: 10.1016/j.jprot.2011.11.018)
Kuboki, T., Kantawong, F., Burchmore, R. , Dalby, M.J. and Kidoaki, S. (2012) 2D-DIGE proteomic analysis of mesenchymal stem cell cultured on the elasticity-tunable hydrogels. Cell Structure and Function, 37(2), pp. 127-139. (doi: 10.1247/csf.12012)
McNamara, L.E., Kantawong, F., Dalby, M.J. , Riehle, M.O. and Burchmore, R.J.S. (2012) Preventing and troubleshooting artefacts in saturation labelled fluorescence 2D difference gel electrophoresis (saturation DiGE). Proteomics, 11(24), pp. 4610-4621. (doi: 10.1002/pmic.201100135)
Tiengwe, C., Marcello, L., Farr, H., Gadelha, C., Burchmore, R. , Barry, J.D., Bell, S.D. and McCulloch, R. (2012) Identification of ORC1/CDC6-interacting factors in trypanosoma brucei reveals critical features of origin recognition complex architecture. PLoS ONE, 7(3), e32674. (doi: 10.1371/journal.pone.0032674) (PMID:22412905) (PMCID:PMC3297607)
Vincent, I.M. , Creek, D.J., Burgess, K., Woods, D.J., Burchmore, R.J.S. and Barrett, M.P. (2012) Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei. PLoS Neglected Tropical Diseases, 6(5), e1618. (doi: 10.1371/journal.pntd.0001618) (PMID:22563508) (PMCID:PMC3341325)
Hounsome, J. D.A., Baillie, S., Noofeli, M., Riboldi-Tunnicliffe, A., Burchmore, R. J.S. , Isaacs, N. W. and Davies, R. L. (2011) Outer membrane protein A of bovine and ovine isolates of mannheimia haemolytica is surface exposed and contains host species-specific epitopes. Infection and Immunity, 79(11), pp. 4332-4341. (doi: 10.1128/IAI.05469-11) (PMID:21896777) (PMCID:PMC3257919)
Higon, M. et al. (2011) Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni. Parasitology, 138(12), pp. 1607-1619. (doi: 10.1017/S0031182011000412)
Barrett, M.P. , Vincent, I.M. , Burchmore, R.J.S. , Kazibwe, A.J.N. and Matovu, E. (2011) Drug resistance in human African trypanosomiasis. Future Microbiology, 6(9), pp. 1037-1047. (doi: 10.2217/fmb.11.88) (PMID:21958143)
Wang, D. et al. (2011) Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds. Journal of Biological Chemistry, 286(34), pp. 29922-29931. (doi: 10.1074/jbc.M111.233858) (PMID:21724850) (PMCID:PMC3191033)
Kantawong, F., Robertson, M.E., Gadegaard, N. , Oreffo, R.O.C., Burchmore, R.J. and Dalby, M.J. (2011) Protein expression of STRO-1 cells in response to different topographic features. Journal of Tissue Engineering, 2011, 534603. (doi: 10.4061/2011/534603) (PMID:21772957) (PMCID:PMC3136090)
Gerou-Ferriani, M., McBrearty, A.R., Burchmore, R.J. , Jayawardena, K.G.I., Eckersall, P.D. and Morris, J.S. (2011) Agarose gel serum protein electrophoresis in cats with and without lymphoma and preliminary results of tandem mass fingerprinting analysis. Veterinary Clinical Pathology, 40(2), pp. 159-173. (doi: 10.1111/j.1939-165X.2011.00310.x)
Ward, C.P., Wong, P.E., Burchmore, R.J.S. , De Koning, H.P. and Barrett, M.P. (2011) Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns. Antimicrobial Agents and Chemotherapy, 55(5), pp. 2352-2361. (doi: 10.1128/AAC.01551-10)
Naula, C.M. , Logan, F.M., Wong, P.E., Barrett, M.P. and Burchmore, R.J. (2010) A glucose transporter can mediate ribose uptake: definition of residues that confer substrate specificity in a sugar transporter. Journal of Biological Chemistry, 285(39), pp. 29721-29728. (doi: 10.1074/jbc.M110.106815)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)
Murphy, L., Eckersall, P.D., Bishop, S.C., Pettit, J.J., Huntley, J.F., Burchmore, R.J.S. and Stear, M.J. (2010) Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta. Parasitology, 137(8), pp. 1249-1260. (doi: 10.1017/S0031182010000028)
Szoor, B., Ruberto, I., Burchmore, R.J.S. and Matthews, K.R. (2010) A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway. Genes and Development, 24(12), pp. 1306-1316. (doi: 10.1101/gad.570310)
Burchmore, R.J.S. (2010) Neuroproteomics. Expert Review of Proteomics, 7(3), pp. 331-332. (doi: 10.1586/epr.10.17)
Henriquez, F.L., Campbell, S.A., Roberts, C.W., Mullen, A.B., Burchmore, R. and Carter, K.C. (2010) Vaccination with recombinant Leishmania donovani gamma-glutamylcysteine synthetase fusion protein protects against L. donovani infection. Journal of Parasitology, 96(5), pp. 929-936. (doi: 10.1645/ge-2360.1) (PMID:20950100)
McNamara, L.E., Dalby, M.J., Riehle, M.O. and Burchmore, R.J.S. (2010) Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications. Journal of the Royal Society: Interface, 7(Sppl 1), S107-S118. (doi: 10.1098/rsif.2009.0177.focus)
Stewart, M.L. et al. (2010) Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes. Eukaryotic Cell, 9(2), pp. 336-343. (doi: 10.1128/EC.00200-09) (PMID:19966032) (PMCID:PMC2823006)
Vincent, I., Scotcher, J. and Burchmore, R. (2010) Sixth exploratory measurement science group symposium. Expert Review of Proteomics, 7(1), pp. 19-20. (doi: 10.1586/epr.09.88)
Romero, I. C., Mehaffy, C., Burchmore, R. J. , Dobos-Elder, K., Brennan, P. and Walker, J. (2010) Identification of promoter-binding proteins of the fbp A and C genes in Mycobacterium tuberculosis. Tuberculosis, 90(1), pp. 25-30. (doi: 10.1016/j.tube.2009.10.001)
Luu, V., Brems, S., Hoheisel, J.D., Burchmore, R. , Guilbride, D.L. and Clayton, C. (2010) Corrigendum to "Functional analysis of Trypanosoma brucei PUF1" [Mol. Biochem. Parasitol. 150 (2006) 340–349]. Molecular and Biochemical Parasitology, 169(1), p. 70. (doi: 10.1016/j.molbiopara.2009.09.003)
Daneshevar, H., Molaei, M. M., Kamiabi, H., Burchmore, R.J.S. , Hagan, P. and Phillips, R.S. (2010) Gentamicin-attenuated Leishmania infantum: cellular immunity production and protection of dogs against experimental canine leishmaniasis. Parasite Immunology, 32(11-12), pp. 722-730. (doi: 10.1111/j.1365-3024.2010.01237.x)
Mutapi, F., Bourke, C., Harcus, Y., Midzi, N., Mduluza, T., Turner, C.M.R., Burchmore, R.J.S. and Maizels, R.M. (2010) Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4. Parasite Immunology, 33(3), pp. 181-192. (doi: 10.1111/j.1365-3024.2010.01270.x)
Vincent, I.M. , Creek, D., Watson, D.G., Kamleh, M.A., Woods, D.J., Wong, P.E., Burchmore, R.J.S. and Barrett, M.P. (2010) A molecular mechanism for eflornithine resistance in African trypanosomes. PLoS Pathogens, 6(11), e1001204. (doi: 10.1371/journal.ppat.1001204) (PMID:21124824) (PMCID:PMC2991269)
Ward, C. P., Burgess, K. E.V., Burchmore, R.J.S. , Barrett, M.P. and De Koning, H.P. (2010) A fluorescence-based assay for the uptake of CPD0801 (DB829) by African trypanosomes. Molecular and Biochemical Parasitology, 174(2), pp. 145-149. (doi: 10.1016/j.molbiopara.2010.07.002)
Kantawong, F., Burchmore, R.J.S. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Proteomic analysis of human osteoprogenitor response to disordered nanotopography. Journal of the Royal Society: Interface, (doi: 10.1098/rsif.2008.0447)
Ataei, S., Burchmore, R. , Hodgson, J. C., Finucane, A., Parton, R. and Coote, J. G. (2009) Identification of immunogenic proteins associated with protection against haemorrhagic septicaemia after vaccination of calves with a live-attenuated aroA derivative of Pasteurella multocida B:2. Research in Veterinary Science, 87(2), pp. 207-210. (doi: 10.1016/j.rvsc.2009.01.007)
Daneshvar, H., Burchmore, R., Hagan, P. and Phillips, R. S. (2009) Leishmania major H-line attenuated under pressure of gentamicin, induces a Th1 response which protects susceptible BALB/c mice against infection with virulent L. major. Parasitology, 136(11), pp. 1243-1250. (doi: 10.1017/S0031182009990679)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)
Rossi, L., Riehle, M.O. , McNamara, L.E., Burchmore, R. , Dalby, M.J. , McMurray, R.J., Gadegaard, N. , Ahmed, S. and Tsimbouri, P.M. (2009) Research highlights. Nanomedicine, 4(6), pp. 613-617. (doi: 10.2217/nnm.09.46)
Kantawong, F., Burchmore, R.J.S., Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2009) Differential in-gel electrophoresis (DIGE) analysis of human bone marrow osteoprogenitor cell contact guidance. Acta Biomaterialia, 5(4), pp. 1137-1146. (doi: 10.1016/j.actbio.2008.11.001)
Daneshvar, H., Molaei, M.M., Afshar, R.M., Kamiabi, H., Burchmore, R.J.S. , Hagan, P. and Phillips, R.S. (2009) Gentamicin-attenuated Leishmania infantum: A clinicopathological study in dogs. Veterinary Immunology and Immunopathology, 129(1-2), pp. 28-35. (doi: 10.1016/j.vetimm.2008.12.002)
Dalby, M.J. , McNamara, L.E., Riehle, M.O. , Burchmore, R.J.S. , Kuntanawat, P., McMurray, R.J., Gadegaard, N. and Andar, A. (2008) Research highlights. Nanomedicine, 3(4), pp. 411-414. (doi: 10.2217/17435889.3.4.411)
Mutapi, F., Burchmore, R. , Mduluza, T., Midzi, N., Turner, C. M. R. and Maizels, R. M. (2008) Age‐related and infection intensity–related shifts in antibody recognition of defined protein antigens in a schistosome‐exposed population. Journal of Infectious Diseases, 198(2), pp. 167-175. (doi: 10.1086/589511)
Kamleh, A., Barrett, M.P. , Wildridge, D., Burchmore, R.J.S. , Scheltema, R.A.. and Watson, D.G. (2008) Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules. Rapid Communications in Mass Spectrometry, 22(12), pp. 1912-1918. (doi: 10.1002/rcm.3564)
Bridges, D.J., Pitt, A.R., Hanrahan, O., Brennan, K., Voorheis, H.P., Herzyk, P. , de Koning, H.P. and Burchmore, R.J.S. (2008) Characterisation of the plasma membrane subproteome of bloodstream form Trypanosoma brucei. Proteomics, 8(1), pp. 83-99. (doi: 10.1002/pmic.200700607)
Bridges, D. J., Gould, M. K., Nerima, B., Maser, P., Burchmore, R. J. S. and de Koning, H. P. (2007) Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes. Molecular Pharmacology, 71, pp. 1098-1108. (doi: 10.1124/mol.106.031351)
Kantawong, F., Dalby, M. and Burchmore, R. (2007) Differential proteomics evaluation of osteoprogenitor growth on microgrooved surfaces using bioreactor culture. Comparative Biochemistry and Physiology. Part A: Molecular and Integrative Physiology, 146(4), S192. (doi: 10.1016/j.cbpa.2007.01.420)
Hannigan, A., Burchmore, R. and Wilson, J. (2007) The optimization of Protocols for Proteome difference gel electrophoresis (DiGE) analysis of Preneoplastic skin. Journal of Proteome Research, 6, pp. 3422-3432. (doi: 10.1021/pr0606878)
Naula, C. , Alibu, V., Brock, J., Veitch, N.J. , Burchmore, R.J.S. and Barrett, M. (2007) A new erythrose 4-phosphate dehydrogenase coupled assay for transketolase. Journal of Biochemical and Biophysical Methods, 70(6), pp. 1185-1187. (doi: 10.1016/j.jprot.2007.11.002)
Nelson, M.M., Jones, A.R., Carmen, J.C., Sinai, A.P.,, Burchmore, R. and Wastling, J.M. (2007) Modulation of the host cell proteome by the intracellular apicomplexan parasite Toxoplasma gondii. Infection and Immunity, 76(2), pp. 828-844. (doi: 10.1128/IAI.01115-07)
Luu, V.D., Brems, S., Hoheisel, J.D., Burchmore, R. , Guilbride, D.L. and Clayton, C. (2006) Functional analysis of Trypanosoma brucei PUF1. Molecular and Biochemical Parasitology, 150(2), pp. 340-349. (doi: 10.1016/j.molbiopara.2006.09.007)
Burchmore, R. (2006) Identification of anti-infective targets through comparative proteomics. Expert Review of Anti-Infective Therapy, 4(2), pp. 163-165. (doi: 10.1586/14787210.4.2.163)
Walker, J., Vasquez, J., Gomez, M., Drummelsmith, J., Burchmore, R. , Girard, I. and Ouellette, M. (2006) Identification of developmentally-regulated proteins in Leishmania panamensis promastigotes and by proteome profiling of axenic amastigotes. Molecular and Biochemical Parasitology, 147, pp. 64-73. (doi: 10.1016/j.molbiopara.2006.01.008)
De Koning, H. P. , Bridges, D. J. and Burchmore, R. J. S. (2005) Purine and pyrimidine transport in pathogenic protozoa: From biology to therapy. FEMS Microbiology Reviews, 29(5), pp. 987-1020. (doi: 10.1016/j.femsre.2005.03.004)
Mutapi, F., Burchmore, R., Mduluza, T., Foucher, A., Harcus, Y., Nicoll, G., Midzi, N., Turner, C. and Maizels, R. (2005) Praziquantel treatment of individuals exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens. Journal of Infectious Diseases, 192(6), pp. 1108-1118. (doi: 10.1086/432553) (PMID:16107967)
Stewart, M., Krishna, S., Burchmore, R. , Brun, R., de Koning, H. , Boykin, D., Tidwell, R., Hall, J. and Barrett, M. (2005) Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test. Lancet, 366, pp. 486-487. (doi: 10.1016/S0140-6736(05)66793-1)
de Koning, H. , Anderson, L., Stewart, M., Burchmore, R. , Wallace, L. and Barrett, M. (2004) The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in African trypanosomes. Antimicrobial Agents and Chemotherapy, 48, pp. 1515-1519. (doi: 10.1128/AAC.48.5.1515-1519.2004)
Barrett, M. , Burchmore, R. , Stich, A., Lazzari, J., Frasch, A., Cazzulo, J. and Krishna, S. (2003) The trypanosomiases. Lancet, 362(9394), pp. 1469-1480. (doi: 10.1016/S0140-6736(03)14694-6)
Burchmore, R. (2003) A plethora of targets, a paucity of drugs: Progress towards the development of novel chemotherapies for human African trypanosomiasis. Expert Review of Anti-Infective Therapy, 1(1), pp. 157-165. (doi: 10.1586/14787210.1.1.157)
Burchmore, R. , Rodriguez-Contreras, D., McBride, K., Barrett, M. , Modi, G., Sacks, D. and Landfear, S. (2003) Genetic characterization of glucose transporter function in Leishmania mexicana. Proceedings of the National Academy of Sciences of the United States of America, 100(7), pp. 3901-3906. (doi: 10.1073/pnas.0630165100)
Burchmore, R. , Wallace, L., Candlish, D., Al-Salabi, M., Beal, P., Barrett, M. , Baldwin, S. and de Koning, H. (2003) Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan. Journal of Biological Chemistry, 278(26), pp. 23502-23507. (doi: 10.1074/jbc.M301252200)
Matovu, E. et al. (2003) Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei. Eukaryotic Cell, 2(5), pp. 1003-1008. (doi: 10.1128/EC.2.5.1003-1008.2003)
Maugeri, D., Cazzulo, J., Burchmore, R. , Barrett, M. and Ogbunude, P. (2003) Pentose phosphate metabolism in Leishmania mexicana. Molecular and Biochemical Parasitology, 130(2), pp. 117-125. (doi: 10.1016/S0166-6851(03)00173-7)
Leslie, G., Barrett, M. and Burchmore, R. (2002) Leishmania mexicana: promastigotes migrate through osmotic gradients. Experimental Parasitology, 102(2), pp. 117-120. (doi: 10.1016/S0014-4894(03)00031-6)
Burchmore, R. , Ogbunude, P., Enanga, B. and Barrett, M. (2002) Chemotherapy of human African trypanosomiasis. Current Pharmaceutical Design, 8(4), pp. 257-267. (doi: 10.2174/1381612023396159)
Enanga, B., Burchmore, R. , Stewart, M. and Barrett, M. (2002) Sleeping sickness and the brain. Cellular and Molecular Life Sciences, 59(5), pp. 845-858. (doi: 10.1007/s00018-002-8472-0)
Burchmore, R. , Turner, C. M. R. and Janssen, C. S. (2001) After the genome-where next? Molecular and Biochemical Parasitology, 118(2), pp. 129-131. (doi: 10.1016/S0166-6851(01)00364-4) (PMID:11738702)
Burchmore, R. and Barrett, M. (2001) Life in vacuoles - nutrient acquisition by Leishmania amastigotes. International Journal for Parasitology, 31(12), pp. 1311-1320. (doi: 10.1016/S0020-7519(01)00259-4)
Krishna, S., Woodrow, C.J., Burchmore, R.J.S. , Saliba, K.J. and Kirk, K. (2000) Hexose transport in asexual stages of Plasmodium falciparum and Kinetoplastidae. Parasitology Today, 16(12), pp. 516-521. (doi: 10.1016/s0169-4758(00)01762-2) (PMID:11121848)
Woodrow, C.J., Burchmore, R.J. and Krishna, S. (2000) Hexose permeation pathways in Plasmodium falciparum-infected erythrocytes. Proceedings of the National Academy of Sciences of the United States of America, 97(18), pp. 9931-9936. (doi: 10.1073/pnas.170153097) (PMID:10954735) (PMCID:PMC27630)
Burchmore, R.J.S. and Landfear, S.M. (1998) Differential regulation of multiple glucose transporter genes in Leishmania mexicana. Journal of Biological Chemistry, 273, pp. 29118-29126. (doi: 10.1074/jbc.273.44.29118) (PMID:9786920)
Burchmore, R.J.S. and Hart, D.T. (1995) Glucose transport in amastigotes and promastigotes of Leishmania mexicana mexicana. Molecular and Biochemical Parasitology, 74(1), pp. 77-86. (doi: 10.1016/0166-6851(95)02485-9) (PMID:8719247)
Langford, C.K., Burchmore, R.J.S. , Hart, D.T., Wagner, W. and Landfear, S.M. (1994) Biochemistry and molecular genetics of Leishmania glucose transporters. Parasitology, 108(S1), S73-S83. (doi: 10.1017/s0031182000075740) (PMID:8084658)
Book Sections
Naula, C. and Burchmore, R. (2020) 2D gel electrophoresis analysis of leishmania proteomes. In: Michels, P. A. M., Ginger, M. L. and Zilberstein, D. (eds.) Trypanosomatids: Methods and Protocols. Series: Methods in Molecular Biology. Springer US: New York, pp. 577-586. ISBN 9781071602942 (doi: 10.1007/978-1-0716-0294-2_34)
Burchmore, R. (2013) Proteomics at the host: pathogen interface. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, p. 37. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_11)
Kuleš, J., Mrljak, B., Rafaj, R. B., Selanec, J., Burchmore, R. and Eckersall, P. D. (2013) A proteomic analysis of canine serum during the course of babesiosis. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, pp. 135-138. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_36)
O'Reilly, E. L., Burchmore, R. J. , Eckersall, P. D. and Sparks, N. H. (2013) The effect of microbial challenge on the intestinal proteome of broiler chickens. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, pp. 143-146. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_38)
Schrama, D., Richard, N., Silva, T. S., Conceição, L. E. C., Dias, J. P., Eckersall, D. , Burchmore, R. and Rodrigues, P. M. (2013) Biomarkers of winter disease in gilthead seabream: a proteomics approach. In: de Almeida, A., Eckersall, D., Bencurova, E., Dolinska, S., Mlynarcik, P., Vincova, M. and Bhide, M. (eds.) Farm Animal Proteomics 2013: Proceedings of the 4th Management Committee Meeting and 3rd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002 Košice, Slovakia 25-26 April 2013. Wageningen Academic Publishers: Wageningen, pp. 175-178. ISBN 9789086862221 (doi: 10.3920/978-90-8686-776-9_45)
O'Reilly, E.L., Burchmore, R.J. , Sandilands, V., Sparks, N.H., Walls, C. and Eckersall, P.D. (2012) The plasma proteome and acute phase proteins of broiler chickens with gait abnormalities. In: Rodrigues, P., Eckersall, D. and de Almeida, A. (eds.) Farm Animal Proteomics: Proceedings of the 3rd Managing Committee Meeting and 2nd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002. Series: Topics in safety, reliability, and quality (18). Wageningen Academic Publishers: Wageningen, pp. 177-180. ISBN 9789086861958 (doi: 10.3920/978-90-8686-751-6_42)
Burchmore, R. (2011) Animal parasitology and proteomics. In: Eckersall, P. D. and Whitfield, P. D. (eds.) Methods in Animal Proteomics. Wiley-Blackwell: Chichester, pp. 349-367. ISBN 9780813817910 (doi: 10.1002/9780470960660.ch12)
Conference Proceedings
Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Wilson, D., Herzyk, P. , Eckersall, P. and Zadoks, R. (2015) Using label-free quantitative proteomics and untargeted metabolomics to study bovine mastitis. In: Science with Impact – BSAS Annual Conference 2015, University of Chester, UK, 14-15 Apr 2015, p. 70. (doi: 10.1017/S2040470015000023)
Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Herzyk, P. , Eckersall, P. and Zadoks, R. (2014) Integrative label-free quantitative proteomics study in mastitis. In: Final Showcase Meeting of Farm Animal Proteomics, Milan, Italy, 17-18 Nov 2014, pp. 98-101. ISBN 9789086868100 (doi: 10.3920/978-90-8686-810-0)
Braceland, M., Bickerdike, R., Cockerill, D., Burchmore, R. , Weir, W. and Eckersall, D. (2012) Proteomics in biomarker detection and monitoring of pancreas disease (PD) in atlantic salmon (Salmo salar). In: 3rd Managing Committee Meeting and 2nd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002, Vilamoura, Portugal, 12-13 Apr 2012, pp. 87-90. ISBN 9789086861958 (doi: 10.3920/978-90-8686-751-6_20)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Proteomics to unlock mechanisms of childhood haemorrhagic stroke in COL4A1 syndrome
Glasgow Children`s Hospital Charity
2022 - 2022
- Elucidating Novel Mechanisms For CO2 - Sensing in Plants
Wellcome Trust
2021 - 2022
- Systemic spread of gut bacterial metabolites and the role in host health
Biotechnology and Biological Sciences Research Council
2021 - 2024
- A structure-function analysis of USP7 and NF-kB interaction.
Biotechnology and Biological Sciences Research Council
2020 - 2022
- Bridging epigenetic, metabolism and cell cycle in pathogenic trypanosomatids
Medical Research Council
2019 - 2022
- The Flux Capacitor: How mitochondria modulate metabolic flux and gene expression
Biotechnology and Biological Sciences Research Council
2019 - 2022
- Valorising secondary products from a composite material process
Scottish Funding Council
2019 - 2020
- 2D-based Screening of Effective Synthetic Parts in an Endophytic Fungus for Efficient Production of Enzymes with Post-translation Modifications
The Royal Society of Edinburgh
2018 - 2020
- Joint Doctorate in Molecular Animal Nutrition
European Commission
2018 - 2022
- SFC-GCRF: Biomarker discovery for carriers of haemorrhagic septicaemia in water buffalo
Scottish Funding Council
2016 - 2017
- Discovery and analysis of key components of Calcineurin signalling in malaria infection and transmission
Wellcome Trust
2016 - 2017
- Detection of Biomarkers for Liver Fluke in Sheep Saliva
Scottish Government
2016 - 2018
- Thiol Modification and Redox Signalling
Medical Research Council
2016 - 2018
- Investigating NF-kB p50 phosphorylation and the regulation of transcription
Medical Research Council
2015 - 2018
- Linking the power of -omic technologies to translational research on neglected tropical diseases
British Council
2015 - 2017
- Synergistic microenvironments for non-union bone defects
Medical Research Council
2014 - 2016
- Molecular interactions of Mannheimia haemolytica with the bovine and ovine respiratory tracts using three-dimensional tissue engineering approaches
Biotechnology and Biological Sciences Research Council
2014 - 2018
- Proteolysis and life cycle progression in Leishmania
Medical Research Council
2013 - 2018
- Dynamic surfaces to mimic mesenchymal stem cell niche functions
Biotechnology and Biological Sciences Research Council
2013 - 2016
- Can marine calcifying organisms use proteomic responses to adpat to anthropogenic global change? (ISSF Catalyst Fund)
Wellcome Trust
2011 - 2014
- The silicon trypanosome (SilicoTryp)
Biotechnology and Biological Sciences Research Council
2010 - 2014
- Identification of proteins targeted by salicylic aldehyde inhibitors in Escherichia coli O157
Medical Research Scotland
2008 - 2010
- Drug resistance in African trypanosomes
Medical Research Council
2008 - 2011
- Assessment of the probability of developing resistance to novel trypanocides under consideration for late stage HAT
University of North Carolina at Chapel Hill
2006 - 2010
- The molecular basis of functional divergence between structurally similar monosaccharide transporters in Leishmania
Wellcome Trust
2005 - 2009
- A comparative proteomic analysis of drug resistance in Leishmania
World Health Organization
2004 - 2005
Supervision
- Dritsa, Clio
N/A
Research datasets
2022
Huang, Y., Burchmore, R. , Jonsson, N. , Johnson, P. and Eckersall, D. (2022) Technical report: In-gel sample preparation prior to proteomic analysis of bovine faeces increases protein identifications by removal of high molecular weight glycoproteins. [Data Collection]
2020
Royle, J., Ramírez-Santana, C., Akpunarlieva, S., Donald, C. , Gestuveo, R., Anaya, J.-M., Merits, A., Burchmore, R. , Kohl, A. and Varjak, M. (2020) Glucose-Regulated Protein 78 interacts with Zika virus envelope protein and contributes to a productive infection. [Data Collection]
Additional information
Editorial Board
- 2007 - present: Expert Review of Proteomics - Editorial Board Member
- 2003 - present: Future Drugs
- 2003 - present: Expert Review of Anti-Infective Therapy - Editorial Board Member
Invited International Presentations
- 2006: Brussels, Belgium - Invited Speaker, COST action B22
- 2005: Oregon, USA - Invited Speaker, Oregon Health Sciences University
- 2005: Goa, India - Invited Speaker, Indo-Swedish Parasitology Meeting
- 2001: Colorado, USA - Invited Speaker, FASEB Glucose Transporter Biology Conference
Research Fellowship
- 1997 - 1998: American Heart Association Postdoctoral Fellowship
- 1994 - 1995: American Heart Association Postdoctoral Fellowship