Dr Nicole Upfold

  • Research Associate (Virology)

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2021 | 2020 | 2019 | 2018 | 2016
Number of items: 12.

2025

Smyth, Elliott B., Pisco, João P., Birchall, Kristian, Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Patel, Arvind H. ORCID logoORCID: https://orcid.org/0000-0003-4600-2047, Foster, Richard and Large, Jonathan M. (2025) Design and synthesis of pyrazoline inhibitors of SARS-CoV-2 NSP14. ACS Medicinal Chemistry Letters, 16(10), pp. 1918-1926. (doi: 10.1021/acsmedchemlett.5c00155)

Furnon, W. et al. (2025) Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic. Nature Microbiology, 10, pp. 77-93. (doi: 10.1038/s41564-024-01878-5) (PMID:39753670) (PMCID:PMC11726466)

Turnbull, M. L. et al. (2025) The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution. Nature Communications, 16, 11042. (doi: 10.1038/s41467-025-67234-1) (PMID:41398153) (PMCID:PMC12706089)

2024

Turnbull, M. L. et al. (2024) Polygenic determinants OF H5N1 adaptation to bovine cells. bioRxiv, (doi: 10.1101/2024.11.29.626120) (PMID:PPR948676)

Samolej, Jerzy, Correa Mendonca, Diogo ORCID logoORCID: https://orcid.org/0000-0003-2356-8750, Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, McElwee, Marion, Landsberger, Mariann, Yakimovich, Artur, Patel, Arvind H. ORCID logoORCID: https://orcid.org/0000-0003-4600-2047, Strang, Blair L. and Mercer, Jason (2024) Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses. Microbiology Spectrum, 12(4), e04072-23. (doi: 10.1128/spectrum.04072-23) (PMID:38376353) (PMCID:PMC10986486)

2023

Meehan, G. R. et al. (2023) Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. PLoS Pathogens, 19(11), e1011589. (doi: 10.1371/journal.ppat.1011589) (PMID:37934791) (PMCID:PMC10656012)

2021

Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Luke, Garry A. and Knox, Caroline (2021) Occurrence of human enteric viruses in water sources and shellfish: a focus on Africa. Food and Environmental Virology, 13(1), pp. 1-31. (doi: 10.1007/s12560-020-09456-8) (PMID:33501612) (PMCID:PMC7837882)

2020

Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Ross, Caroline, Bishop, Özlem Tastan and Knox, Caroline (2020) The in silico prediction of hotspot residues that contribute to the structural stability of subunit interfaces of a picornavirus capsid. Viruses, 12(4), 387. (doi: 10.3390/v12040387) (PMID:32244486) (PMCID:PMC7232237)

Onosi, Oikwathaile, Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Jukes, Michael D., Luke, Garry A. and Knox, Caroline (2020) The first detection of human bocavirus species 2 and 3 in raw sewage and mussels in South Africa. Food and Environmental Virology, 12(1), pp. 84-88. (doi: 10.1007/s12560-019-09417-w) (PMID:31786741)

2019

Onosi, Oikwathaile, Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Jukes, Michael D., Luke, Garry A. and Knox, Caroline (2019) The first molecular detection of Aichi virus 1 in raw sewage and mussels collected in South Africa. Food and Environmental Virology, 11(1), pp. 96-100. (doi: 10.1007/s12560-018-9362-4) (PMID:30560489)

2018

Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Ross, Caroline, Bishop, Özlem Tastan, Luke, Garry A. and Knox, Caroline (2018) The generation and characterisation of neutralising antibodies against the Theiler’s murine encephalomyelitis virus (TMEV) GDVII capsid reveals the potential binding site of the host cell co-receptor, heparan sulfate. Virus Research, 244, pp. 153-163. (doi: 10.1016/j.virusres.2017.11.017) (PMID:29155139)

2016

Ross, Caroline, Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Luke, Garry A., Bishop, Özlem Tastan and Knox, Caroline (2016) Subcellular localisation of Theiler's murine encephalomyelitis virus (TMEV) capsid subunit VP1 vis-á-vis host protein Hsp90. Virus Research, 222, pp. 53-63. (doi: 10.1016/j.virusres.2016.06.003) (PMID:27269472)

This list was generated on Fri Jan 2 18:25:05 2026 GMT.
Jump to: Articles
Number of items: 12.

Articles

Smyth, Elliott B., Pisco, João P., Birchall, Kristian, Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Patel, Arvind H. ORCID logoORCID: https://orcid.org/0000-0003-4600-2047, Foster, Richard and Large, Jonathan M. (2025) Design and synthesis of pyrazoline inhibitors of SARS-CoV-2 NSP14. ACS Medicinal Chemistry Letters, 16(10), pp. 1918-1926. (doi: 10.1021/acsmedchemlett.5c00155)

Furnon, W. et al. (2025) Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic. Nature Microbiology, 10, pp. 77-93. (doi: 10.1038/s41564-024-01878-5) (PMID:39753670) (PMCID:PMC11726466)

Turnbull, M. L. et al. (2025) The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution. Nature Communications, 16, 11042. (doi: 10.1038/s41467-025-67234-1) (PMID:41398153) (PMCID:PMC12706089)

Turnbull, M. L. et al. (2024) Polygenic determinants OF H5N1 adaptation to bovine cells. bioRxiv, (doi: 10.1101/2024.11.29.626120) (PMID:PPR948676)

Samolej, Jerzy, Correa Mendonca, Diogo ORCID logoORCID: https://orcid.org/0000-0003-2356-8750, Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, McElwee, Marion, Landsberger, Mariann, Yakimovich, Artur, Patel, Arvind H. ORCID logoORCID: https://orcid.org/0000-0003-4600-2047, Strang, Blair L. and Mercer, Jason (2024) Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses. Microbiology Spectrum, 12(4), e04072-23. (doi: 10.1128/spectrum.04072-23) (PMID:38376353) (PMCID:PMC10986486)

Meehan, G. R. et al. (2023) Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. PLoS Pathogens, 19(11), e1011589. (doi: 10.1371/journal.ppat.1011589) (PMID:37934791) (PMCID:PMC10656012)

Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Luke, Garry A. and Knox, Caroline (2021) Occurrence of human enteric viruses in water sources and shellfish: a focus on Africa. Food and Environmental Virology, 13(1), pp. 1-31. (doi: 10.1007/s12560-020-09456-8) (PMID:33501612) (PMCID:PMC7837882)

Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Ross, Caroline, Bishop, Özlem Tastan and Knox, Caroline (2020) The in silico prediction of hotspot residues that contribute to the structural stability of subunit interfaces of a picornavirus capsid. Viruses, 12(4), 387. (doi: 10.3390/v12040387) (PMID:32244486) (PMCID:PMC7232237)

Onosi, Oikwathaile, Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Jukes, Michael D., Luke, Garry A. and Knox, Caroline (2020) The first detection of human bocavirus species 2 and 3 in raw sewage and mussels in South Africa. Food and Environmental Virology, 12(1), pp. 84-88. (doi: 10.1007/s12560-019-09417-w) (PMID:31786741)

Onosi, Oikwathaile, Upfold, Nicole S. ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Jukes, Michael D., Luke, Garry A. and Knox, Caroline (2019) The first molecular detection of Aichi virus 1 in raw sewage and mussels collected in South Africa. Food and Environmental Virology, 11(1), pp. 96-100. (doi: 10.1007/s12560-018-9362-4) (PMID:30560489)

Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Ross, Caroline, Bishop, Özlem Tastan, Luke, Garry A. and Knox, Caroline (2018) The generation and characterisation of neutralising antibodies against the Theiler’s murine encephalomyelitis virus (TMEV) GDVII capsid reveals the potential binding site of the host cell co-receptor, heparan sulfate. Virus Research, 244, pp. 153-163. (doi: 10.1016/j.virusres.2017.11.017) (PMID:29155139)

Ross, Caroline, Upfold, Nicole ORCID logoORCID: https://orcid.org/0000-0001-8556-0370, Luke, Garry A., Bishop, Özlem Tastan and Knox, Caroline (2016) Subcellular localisation of Theiler's murine encephalomyelitis virus (TMEV) capsid subunit VP1 vis-á-vis host protein Hsp90. Virus Research, 222, pp. 53-63. (doi: 10.1016/j.virusres.2016.06.003) (PMID:27269472)

This list was generated on Fri Jan 2 18:25:05 2026 GMT.

Research datasets

Jump to: 2025 | 2024 | 2023
Number of items: 3.

2025

Turnbull, M. , Zakaria, M. K. , Upfold, N. , Bakshi, S., Magill, C., DAS, U. R., Clarke, A. , Mojsiejczuk, L., Herder, V. , Dee, K., Liu, N., Folwarczna, M., Ilia, G., Schultz, V. , Chen, H., Devlin, R., McCowan, J., Young, A., Po, W. W., Smollett, K. , Yaseen, H., Ross, R., Bhide, A., van Kekem, B., Fouchier, R., da Silva Felipe, A., Iqbal, M., Roberts, E. , Hughes, J. , Werling, D., Murcia, P. and Palmarini, M. (2025) The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution. [Data Collection]

2024

Furnon, W. , Cowton, V. M., De Lorenzo, G. , Orton, R. , Herder, V. , Cantoni, D. , Ilia, G., Correa Mendonca, D. , Kerr, K., Allan, J., Upfold, N. , Meehan, G. R. , Bakshi, S., Das, U. R., Molina Arias, S., McElwee, M., Little, S., Logan, N., Kwok, K. , Smollett, K. , Willett, B. , Da Silva Filipe, A. , Robertson, D. L. , Grove, J. , Patel, A. H. and Palmarini, M. (2024) Phenotypic evolution of SARS-CoV-2 spike throughout the COVID-19 pandemic. [Data Collection]

2023

Meehan, G. , Herder, V. , Allan, J., Huang, X., Kerr, K., Correa Mendonca, D. , Ilia, G., Wright, D. , Nomikou, K., Gu, Q. , Molina Arias, S., Hansmann, F., Hardas, A., Attipa, C., De Lorenzo, G. , Cowton, V., Upfold, N. , Palmalux, N., Brown, J., Barclay, W., Da Silva Filipe, A. , Furnon, W. , Patel, A. and Palmarini, M. (2023) Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. [Data Collection]

This list was generated on Fri Jan 2 18:25:07 2026 GMT.