Ms Lynn Stewart

  • Research Associate (Immunology)

telephone: 0141 330 6267
email: Lynn.Stewart@glasgow.ac.uk

Biography

Lynn graduated in 1997 with a BSc (Honours) Degree in Biology (2:1 grade) from Paisley University. She has over 14 years experience working in a lab environment, firstly as a trainee MLSO in the Pathology Department of the Southern General Hospital. 

After immigrating to Hamilton, Ontario Canada in 2000, she worked for the Director of the Institute of Infection, Immunity and Inflammation in an allergy research lab at McMaster University as a Senior Technician/Lab Manager for 10 years, co-authoring 12 scientific papers. 

On return from Canada in 2010, she was employed for 6 months at Ross Hall Hospital in the multi-disciplinary medical lab.  In August 2010 she was offered a job at Glasgow University as Senior Technician to Prof. Iain McInnes, providing specialized technical support to a small microRNA research group within the Centre of Rheumatic Disease. 

Lynn’s tenure at present is Research Associate within the newly formed GLAZgo Discovery Centre.  Projects that she will be working on include Phenotypic Screening Assays and optimization of multiplex q-PCR and digital PCR. 

She is skilled and certified in various lab techniques including multi-colour FACS acquisition and cell sorting, cell transfection, RNA, DNA and protein extraction, cDNA synthesis, Q-PCR, Luminex multiplex assays, MACS, ELISA and cell culture and regularly teaches these techniques to undergraduate/MSc/Ph.D. students and MDs/Fellows-in-Training/Clinical Research Associates that come to work and study in the lab.

Publications

List by: Type | Date

Jump to: 2017 | 2016 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002
Number of items: 30.

2017

Kurowska-Stolarska, M. et al. (2017) MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications, 8, 15877. (doi:10.1038/ncomms15877) (PMID:28639625) (PMCID:5489689)

2016

Elmesmari, A., Fraser, A. R., Wood, C., Gilchrist, D., Vaughan, D., Stewart, L., McSharry, C., McInnes, I. B. and Kurowska-Stolarska, M. (2016) MicroRNA-155 regulates monocyte chemokine and chemokine receptor expression in Rheumatoid Arthritis. Rheumatology, 55(11), pp. 2056-2065. (doi:10.1093/rheumatology/kew272) (PMID:27411480) (PMCID:PMC5088623)

Kurowska-Stolarska, M. et al. (2016) The role of microRNA-155/LXR pathway in experimental and Idiopathic Pulmonary Fibrosis. Journal of Allergy and Clinical Immunology, (doi:10.1016/j.jaci.2016.09.021) (PMID:27746237) (Early Online Publication)

2011

Reece, P., Thanendran, A., Crawford, L., Tulic, M. K., Thabane, L., Prescott, S. L., Sehmi, R. and Denburg, J. A. (2011) Maternal allergy modulates cord blood hematopoietic progenitor Toll-like receptor expression and function. Journal of Allergy and Clinical Immunology, 127(2), pp. 447-453. (doi:10.1016/j.jaci.2010.11.006)

Alivernini, S. et al. (2011) The role of microRNA-34 and microRNA-22 in dendritic cells and monocyte activation in rheumatoid arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Chicago, IL USA, 4-9 Nov 2011, S654.

2010

Ellis, A. K., Ackerman, S. J., Crawford, L., Du, J., Bedi, R. and Denburg, J. A. (2010) Cord blood molecular biomarkers of eosinophilopoiesis: kinetic analysis of GATA-1, MBP1 and IL-5Rα mRNA expression. Pediatric Allergy and Immunology, 21(4p1), pp. 640-648. (doi:10.1111/j.1399-3038.2010.01003.x)

Ellis, A.K., Fraser, K., Crawford, L. and Denburg, J.A. (2010) Cord blood eosinophil progenitor expression of major basic protein mRNA is associated with maternal atopic sensitization. Journal of Allergy and Clinical Immunology, 125(2), AB231. (doi:10.1016/j.jaci.2009.12.901)

Reece, P., Crawford, L., Baajtes, A., Cyr, M., Sehmi, R. and Denburg, J.A. (2010) Cord blood hemopoietic progenitor cell toll-like receptor expression and function: a mechanism underlying allergic inflammation in early life. Journal of Allergy and Clinical Immunology, 125(2), AB105. (doi:10.1016/j.jaci.2009.12.415)

2009

Ellis, A.K., Crawford, L. and Denburg, J.A. (2009) Cord blood CD34 + hemopoietic progenitor eosinophilic lineage commitment assessed by Q-PCR. Journal of Allergy and Clinical Immunology, 123(2), S225. (doi:10.1016/j.jaci.2008.12.862)

Goronfolah, L.T., Ferrie, P., Schmuck, M., Waserman, S., Denburg, J., Kott, L., Keith, P., Crawford, L. and Fletcher, R. (2009) A double-blind, placebo-controlled, randomized, crossover trial of a mint tea high in rosmarinic acid in adults with nasal polyposis. Journal of Allergy and Clinical Immunology, 123(2), S202-S202. (doi:10.1016/j.jaci.2008.12.771)

Reece, P., Crawford, L. and Denburg, J.A. (2009) Cord blood (BR) progenitor toll- like receptor (TLR) expression: an alternate innate immune pathway in the development of atopy. Journal of Allergy and Clinical Immunology, 123(2), S50-S50. (doi:10.1016/j.jaci.2008.12.158)

2008

Cyr, M. M., Baatjes, A. J., Dorman, S. C., Crawford, L., Sehmi, R., Foley, R., Alam, R., O'Byrne, P. and Denburg, J. A. (2008) In Vitro effects of budesonide on eosinophil-basophil lineage commitment. Open Respiratory Medicine Journal, 2(1), pp. 60-66. (doi:10.2174/1874306400802010060)

2007

Roa, J., Morikawa, H., Crawford, L., Baatjes, A., Duong, M. and Denburg, J. A. (2007) The effects of montelukast on tissue inflammatory and bone marrow responses in murine experimental allergic rhinitis: interaction with interleukin-5 deficiency. Immunology, 122(3), pp. 438-444. (doi:10.1111/j.1365-2567.2007.02664.x)

Crawford, L., Ellis, A.K. and Denburg, J.A. (2007) Kinetics of cord blood eosinophil lineage biomarker mRNA: co-expression of CysLTR1 with GATA-1. Journal of Allergy and Clinical Immunology, 119(1), S215. (doi:10.1016/j.jaci.2006.12.213)

Ellis, A.K., Crawford, L. and Denburg, J.A. (2007) Molecular markers of eosinophilopoiesis: multiplex Q-PCR analysis of GATA-1, MBP and IL-5 receptor mRNA expression in peripheral blood. Journal of Allergy and Clinical Immunology, 119(1), S218. (doi:10.1016/j.jaci.2006.12.225)

2006

Ellis, A.K., Crawford, L. and Denburg, J.A. (2006) Molecular markers of eosinophilopoiesis at birth: kinetics of cord blood GATA-1, MBP and IL-5 receptor expression. Journal of Allergy and Clinical Immunology, 117(2), S60. (doi:10.1016/j.jaci.2005.12.241)

2005

Cyr, M. M., Hayes, L. M., Crawford, L., Baatjes, A. J., Keith, P. K. and Denburg, J. A. (2005) The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study. International Archives of Allergy and Immunology, 138(3), pp. 209-216. (doi:10.1159/000088721)

Li, J., Saito, H., Crawford, L., Inman, M. D., Cyr, M. M. and Denburg, J. A. (2005) Haemopoietic mechanisms in murine allergic upper and lower airway inflammation. Immunology, 114(3), pp. 386-396. (doi:10.1111/j.1365-2567.2005.02109.x)

Cyr, M.M., Crawford, L. and Denburg, J.A. (2005) The effect of lipopolysaccharide (LPS) on cord-blood hemopoietic progenitors. Journal of Allergy and Clinical Immunology, 115(2), S191. (doi:10.1016/j.jaci.2004.12.776)

Morikawa, H., Howie, K., Crawford, L., Cyr, M.M. and Denburg, J.A. (2005) Interactive effects of a cysteinyl leukotriene receptor (CysLT1R) antagonist, montelukast (ML), and IL-5 deficiency in murine experimental allergic rhinitis. Journal of Allergy and Clinical Immunology, 115(2), S194. (doi:10.1016/j.jaci.2004.12.786)

2004

Saito, H., Morikawa, H., Howie, K., Crawford, L., Baatjes, A. J., Denburg, E., Cyr, M. M. and Denburg, J. A. (2004) Effects of a cysteinyl leukotriene receptor antagonist on eosinophil recruitment in experimental allergic rhinitis. Immunology, 113(2), pp. 246-252. (doi:10.1111/j.1365-2567.2004.01944.x)

Crawford, L., Baatjes, A.J., Cyr, M.M., Hayes, L.M. and Denburg, J.A. (2004) Kinetics of GATA-1 expression in cord blood eosinophil progenitors: effects of Budesonide. Journal of Allergy and Clinical Immunology, 113(2), S169. (doi:10.1016/j.jaci.2004.01.042)

Li, J., Saito, H., Crawford, L. and Denburg, J.A. (2004) Local and systemic responses in murine experimental allergic airways inflammation: mechanisms linking rhinitis to asthma. Journal of Allergy and Clinical Immunology, 113(2), S186-S187. (doi:10.1016/j.jaci.2004.01.109)

2003

Li, J., Saito, H., Crawford, L. and Denburg, J.A. (2003) Responses of bone-marrow eosinophil/basophil progenitors in experimental mouse models of upper and/or lower airway inflammation. Journal of Allergy and Clinical Immunology, 111(2), S280. (doi:10.1016/S0091-6749(03)81005-9)

Saito, H., Crawford, L., Denburg, E. and Denburg, J.A. (2003) The role of cysteinyl leukotrienes (CysLTS) in bone marrow responses in murine experimental allergic rhinitis: blockade of eosinophil production and tissue eosinophilia by a CysLT1 receptor antagonist. Journal of Allergy and Clinical Immunology, 111(2), S266. (doi:10.1016/S0091-6749(03)80952-1)

2002

Saito, H., Matsumoto, K., Denburg, A. E., Crawford, L., Ellis, R., Inman, M. D., Sehmi, R., Takatsu, K., Matthaei, K. I. and Denburg, J. A. (2002) Pathogenesis of murine experimental allergic rhinitis: a study of local and systemic consequences of IL-5 deficiency. Journal of Immunology, 168(6), pp. 3017-3023. (doi:10.4049/jimmunol.168.6.3017)

Baatjes, A. J., Crawford, L., Cyr, M. M., Dorman, S., Foley, R., Hayes, L. M., Sehmi, R. and Denburg, J. A. (2002) The combined effect of all trans retinoic acid and the glucocorticoid, budesonide, on eosinophil differentiation from cord blood-derived CD34+ progenitor cells in vitro. Journal of Allergy and Clinical Immunology, 109(1), S166. (doi:10.1016/S0091-6749(02)81626-8)

Crawford, L., Saito, H., Inman, M. D. and Denburg, J. A. (2002) Effects of the cysteinyl leukotriene receptor antagonist, montelukast, on eosinophil differentiation in an experimental mouse model of allergic rhinitis. Journal of Allergy and Clinical Immunology, 109(1), S296-S296. (doi:10.1016/S0091-6749(02)82041-3)

Cyr, M. M., Baatjes, A. J., Hayes, L. M., Crawford, L. and Denburg, J. A. (2002) The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study. Journal of Allergy and Clinical Immunology, 109(1), S117. (doi:10.1016/S0091-6749(02)81465-8)

Saito, H., Crawford, L., Denburg, A., Inman, M. D. and Denburg, J. A. (2002) Is IL-5 suppression sufficient to control eosinophilic airway allery?: studies of experimental allergic rhinitis in IL-5 deficient mice. Journal of Allergy and Clinical Immunology, 109(1), S255. (doi:10.1016/S0091-6749(02)81913-3)

This list was generated on Tue Oct 17 13:30:11 2017 BST.
Number of items: 30.

Articles

Kurowska-Stolarska, M. et al. (2017) MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications, 8, 15877. (doi:10.1038/ncomms15877) (PMID:28639625) (PMCID:5489689)

Elmesmari, A., Fraser, A. R., Wood, C., Gilchrist, D., Vaughan, D., Stewart, L., McSharry, C., McInnes, I. B. and Kurowska-Stolarska, M. (2016) MicroRNA-155 regulates monocyte chemokine and chemokine receptor expression in Rheumatoid Arthritis. Rheumatology, 55(11), pp. 2056-2065. (doi:10.1093/rheumatology/kew272) (PMID:27411480) (PMCID:PMC5088623)

Kurowska-Stolarska, M. et al. (2016) The role of microRNA-155/LXR pathway in experimental and Idiopathic Pulmonary Fibrosis. Journal of Allergy and Clinical Immunology, (doi:10.1016/j.jaci.2016.09.021) (PMID:27746237) (Early Online Publication)

Reece, P., Thanendran, A., Crawford, L., Tulic, M. K., Thabane, L., Prescott, S. L., Sehmi, R. and Denburg, J. A. (2011) Maternal allergy modulates cord blood hematopoietic progenitor Toll-like receptor expression and function. Journal of Allergy and Clinical Immunology, 127(2), pp. 447-453. (doi:10.1016/j.jaci.2010.11.006)

Ellis, A. K., Ackerman, S. J., Crawford, L., Du, J., Bedi, R. and Denburg, J. A. (2010) Cord blood molecular biomarkers of eosinophilopoiesis: kinetic analysis of GATA-1, MBP1 and IL-5Rα mRNA expression. Pediatric Allergy and Immunology, 21(4p1), pp. 640-648. (doi:10.1111/j.1399-3038.2010.01003.x)

Ellis, A.K., Fraser, K., Crawford, L. and Denburg, J.A. (2010) Cord blood eosinophil progenitor expression of major basic protein mRNA is associated with maternal atopic sensitization. Journal of Allergy and Clinical Immunology, 125(2), AB231. (doi:10.1016/j.jaci.2009.12.901)

Reece, P., Crawford, L., Baajtes, A., Cyr, M., Sehmi, R. and Denburg, J.A. (2010) Cord blood hemopoietic progenitor cell toll-like receptor expression and function: a mechanism underlying allergic inflammation in early life. Journal of Allergy and Clinical Immunology, 125(2), AB105. (doi:10.1016/j.jaci.2009.12.415)

Ellis, A.K., Crawford, L. and Denburg, J.A. (2009) Cord blood CD34 + hemopoietic progenitor eosinophilic lineage commitment assessed by Q-PCR. Journal of Allergy and Clinical Immunology, 123(2), S225. (doi:10.1016/j.jaci.2008.12.862)

Goronfolah, L.T., Ferrie, P., Schmuck, M., Waserman, S., Denburg, J., Kott, L., Keith, P., Crawford, L. and Fletcher, R. (2009) A double-blind, placebo-controlled, randomized, crossover trial of a mint tea high in rosmarinic acid in adults with nasal polyposis. Journal of Allergy and Clinical Immunology, 123(2), S202-S202. (doi:10.1016/j.jaci.2008.12.771)

Reece, P., Crawford, L. and Denburg, J.A. (2009) Cord blood (BR) progenitor toll- like receptor (TLR) expression: an alternate innate immune pathway in the development of atopy. Journal of Allergy and Clinical Immunology, 123(2), S50-S50. (doi:10.1016/j.jaci.2008.12.158)

Cyr, M. M., Baatjes, A. J., Dorman, S. C., Crawford, L., Sehmi, R., Foley, R., Alam, R., O'Byrne, P. and Denburg, J. A. (2008) In Vitro effects of budesonide on eosinophil-basophil lineage commitment. Open Respiratory Medicine Journal, 2(1), pp. 60-66. (doi:10.2174/1874306400802010060)

Roa, J., Morikawa, H., Crawford, L., Baatjes, A., Duong, M. and Denburg, J. A. (2007) The effects of montelukast on tissue inflammatory and bone marrow responses in murine experimental allergic rhinitis: interaction with interleukin-5 deficiency. Immunology, 122(3), pp. 438-444. (doi:10.1111/j.1365-2567.2007.02664.x)

Crawford, L., Ellis, A.K. and Denburg, J.A. (2007) Kinetics of cord blood eosinophil lineage biomarker mRNA: co-expression of CysLTR1 with GATA-1. Journal of Allergy and Clinical Immunology, 119(1), S215. (doi:10.1016/j.jaci.2006.12.213)

Ellis, A.K., Crawford, L. and Denburg, J.A. (2007) Molecular markers of eosinophilopoiesis: multiplex Q-PCR analysis of GATA-1, MBP and IL-5 receptor mRNA expression in peripheral blood. Journal of Allergy and Clinical Immunology, 119(1), S218. (doi:10.1016/j.jaci.2006.12.225)

Ellis, A.K., Crawford, L. and Denburg, J.A. (2006) Molecular markers of eosinophilopoiesis at birth: kinetics of cord blood GATA-1, MBP and IL-5 receptor expression. Journal of Allergy and Clinical Immunology, 117(2), S60. (doi:10.1016/j.jaci.2005.12.241)

Cyr, M. M., Hayes, L. M., Crawford, L., Baatjes, A. J., Keith, P. K. and Denburg, J. A. (2005) The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study. International Archives of Allergy and Immunology, 138(3), pp. 209-216. (doi:10.1159/000088721)

Li, J., Saito, H., Crawford, L., Inman, M. D., Cyr, M. M. and Denburg, J. A. (2005) Haemopoietic mechanisms in murine allergic upper and lower airway inflammation. Immunology, 114(3), pp. 386-396. (doi:10.1111/j.1365-2567.2005.02109.x)

Cyr, M.M., Crawford, L. and Denburg, J.A. (2005) The effect of lipopolysaccharide (LPS) on cord-blood hemopoietic progenitors. Journal of Allergy and Clinical Immunology, 115(2), S191. (doi:10.1016/j.jaci.2004.12.776)

Morikawa, H., Howie, K., Crawford, L., Cyr, M.M. and Denburg, J.A. (2005) Interactive effects of a cysteinyl leukotriene receptor (CysLT1R) antagonist, montelukast (ML), and IL-5 deficiency in murine experimental allergic rhinitis. Journal of Allergy and Clinical Immunology, 115(2), S194. (doi:10.1016/j.jaci.2004.12.786)

Saito, H., Morikawa, H., Howie, K., Crawford, L., Baatjes, A. J., Denburg, E., Cyr, M. M. and Denburg, J. A. (2004) Effects of a cysteinyl leukotriene receptor antagonist on eosinophil recruitment in experimental allergic rhinitis. Immunology, 113(2), pp. 246-252. (doi:10.1111/j.1365-2567.2004.01944.x)

Crawford, L., Baatjes, A.J., Cyr, M.M., Hayes, L.M. and Denburg, J.A. (2004) Kinetics of GATA-1 expression in cord blood eosinophil progenitors: effects of Budesonide. Journal of Allergy and Clinical Immunology, 113(2), S169. (doi:10.1016/j.jaci.2004.01.042)

Li, J., Saito, H., Crawford, L. and Denburg, J.A. (2004) Local and systemic responses in murine experimental allergic airways inflammation: mechanisms linking rhinitis to asthma. Journal of Allergy and Clinical Immunology, 113(2), S186-S187. (doi:10.1016/j.jaci.2004.01.109)

Li, J., Saito, H., Crawford, L. and Denburg, J.A. (2003) Responses of bone-marrow eosinophil/basophil progenitors in experimental mouse models of upper and/or lower airway inflammation. Journal of Allergy and Clinical Immunology, 111(2), S280. (doi:10.1016/S0091-6749(03)81005-9)

Saito, H., Crawford, L., Denburg, E. and Denburg, J.A. (2003) The role of cysteinyl leukotrienes (CysLTS) in bone marrow responses in murine experimental allergic rhinitis: blockade of eosinophil production and tissue eosinophilia by a CysLT1 receptor antagonist. Journal of Allergy and Clinical Immunology, 111(2), S266. (doi:10.1016/S0091-6749(03)80952-1)

Saito, H., Matsumoto, K., Denburg, A. E., Crawford, L., Ellis, R., Inman, M. D., Sehmi, R., Takatsu, K., Matthaei, K. I. and Denburg, J. A. (2002) Pathogenesis of murine experimental allergic rhinitis: a study of local and systemic consequences of IL-5 deficiency. Journal of Immunology, 168(6), pp. 3017-3023. (doi:10.4049/jimmunol.168.6.3017)

Baatjes, A. J., Crawford, L., Cyr, M. M., Dorman, S., Foley, R., Hayes, L. M., Sehmi, R. and Denburg, J. A. (2002) The combined effect of all trans retinoic acid and the glucocorticoid, budesonide, on eosinophil differentiation from cord blood-derived CD34+ progenitor cells in vitro. Journal of Allergy and Clinical Immunology, 109(1), S166. (doi:10.1016/S0091-6749(02)81626-8)

Crawford, L., Saito, H., Inman, M. D. and Denburg, J. A. (2002) Effects of the cysteinyl leukotriene receptor antagonist, montelukast, on eosinophil differentiation in an experimental mouse model of allergic rhinitis. Journal of Allergy and Clinical Immunology, 109(1), S296-S296. (doi:10.1016/S0091-6749(02)82041-3)

Cyr, M. M., Baatjes, A. J., Hayes, L. M., Crawford, L. and Denburg, J. A. (2002) The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study. Journal of Allergy and Clinical Immunology, 109(1), S117. (doi:10.1016/S0091-6749(02)81465-8)

Saito, H., Crawford, L., Denburg, A., Inman, M. D. and Denburg, J. A. (2002) Is IL-5 suppression sufficient to control eosinophilic airway allery?: studies of experimental allergic rhinitis in IL-5 deficient mice. Journal of Allergy and Clinical Immunology, 109(1), S255. (doi:10.1016/S0091-6749(02)81913-3)

Conference Proceedings

Alivernini, S. et al. (2011) The role of microRNA-34 and microRNA-22 in dendritic cells and monocyte activation in rheumatoid arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Chicago, IL USA, 4-9 Nov 2011, S654.

This list was generated on Tue Oct 17 13:30:11 2017 BST.