Dr Gavin Meehan
- Research Associate (Immunology)
I received a MSci (hons) degree in pharmacology from the University of Glasgow in 2011. As part of this degree I undertook research in the life sciences industry, working for both a local biotech company, Biofilm, and the pharmaceutical company, Pfizer. Upon completion of my undergraduate degree, I began a Ph.D., studying the roles of anti-glycolipid antibodies in autoimmune neuropathies, with Prof. Hugh Willison at the University of Glasgow.
After my Ph.D. I began my postdoctoral research at the University of Glasgow in the Laboratory of Immune Cell Visualisation and Examination (LIVE) under Profs James Brewer and Paul Garside. My research in this laboratory has focussed on the roles of the immune system during autoimmune diseases and infections with a particular focus on studying the dynamics of these processes using multiphoton microscopy.
I first developed an interest in the role of the immune system in autoimmune diseases during my Ph.D. where I created a series of anti-glycolipid antibodies for studying paralytic autoimmune neuropathies. Following on from my PhD, I was keen to expand my knowledge of immunology further and decided to join the Laboratory of Immune Cell Visualisation and Examination (LIVE). As part of LIVE, I was able to study various other autoimmune diseases including scleroderma and rheumatoid arthritis as well as infective diseases including malaria.
This research has involved the use of a number of techniques including multiparameter flow cytometry, cell-based assays, whole body imaging and multiphoton microscopy. One technique in which I am particularly interested is intravital imaging, which I use for studying the temporal and dynamic behaviours of immune cells in disease. Several of my projects have involved the use and development of mouse models for this purpose, allowing for the tracking and visualisation of both host and parasite interactions and responses in real time. This has allowed me to study these cells in a manner that is not possible with other methods and has proven useful for fostering collaborations with other researchers both within the University and across the UK.