Dr Daniel Walker Research Interests
We aim to develop highly selective and potent protein antibiotics (bacteriocins) for the treatment of chronic bacterial infections and for use in agricultural applications. In addition, we are interested in determining the mechanism of action of bacteriocins, studying fundamental aspects of membrane biogenesis in Gram-negative bacteria and deleloping cross-linking stratagies for structural proteomics.
Current research projects include:
- Protein antibiotics as novel therapeutic agents for the treatment of chronic biofilm-mediated infection.
- Harnessing bacteriocins active against bacterial plant pathogens.
- Mapping protein-protein interactions in the translocation and assembly module (TAM) complex involved in autotransporter biogenesis.
- Development of cross-linking strategies for structural proteomics