Dr Aysin Tulunay Virlan
- Research Associate (Immunology & Infection)
telephone:
01413308132
email:
Aysin.TulunayVirlan@glasgow.ac.uk
Institute of Infection Immunity, and Inflammation, GBRC Room B428 Level 4, 120 University Place, Glasgow, G12 8TA
Publications
2025
Ansalone, C. et al. (2025) Spatial profiling of giant cell arteritis tissues reveals immune heterogeneity and potential predictors of glucocorticoid response. Annals of the Rheumatic Diseases, (doi: 10.1016/j.ard.2025.09.009) (PMID:41109780) (Accepted for Publication)
Wang, L. et al. (2025) Human regulatory B cells suppress autoimmune disease primarily via interleukin-37. Journal of Autoimmunity, 153, 103415. (doi: 10.1016/j.jaut.2025.103415) (PMID:40250016)
2024
Deniz, Rabia, Tulunay-Virlan, Aysın ORCID: https://orcid.org/0000-0003-4735-9902, Ture Ozdemir, Filiz, Ugur Unal, Ali, Ozen, Gulsen, Alibaz-Oner, Fatma, Aydin-Tatli, Imren and Direskeneli, Haner
(2024)
Analysis of proinflammatory cytokine responses in Takayasu arteritis.
Archives of Rheumatology, 39(4),
pp. 598-606.
(doi: 10.46497/ArchRheumatol.2024.10790)
(PMID:40060124)
(PMCID:PMC11883268)
Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Cafaro, Giacomo, Sunzini, Flavia, Degboe, Yannick and Christodoulou, Maria-Ionna
(2024)
Editorial: immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimmunity and immune-related adverse effects.
Frontiers in Oncology, 14,
1476475.
(doi: 10.3389/fonc.2024.1476475)
(PMID:39252949)
(PMCID:PMC11381221)
2023
Eraslan, Muhsin, Çerman, Eren, Bozkurt, Süheyla, Genç, Deniz, Tulunay Virlan, Aysın ORCID: https://orcid.org/0000-0003-4735-9902, Subaşı Demir, Cansu, Akkoç, Tolga, Karaöz, Erdal and Akkoç, Tunç
(2023)
Mesenchymal stem cells differentiate to retinal ganglion-like cells in rat glaucoma model induced by polystyrene microspheres.
Tissue and Cell, 84,
102199.
(doi: 10.1016/j.tice.2023.102199)
(PMID:37633122)
Ooms, A. et al. (2023) Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis. BMJ Open, 13(9), e078539. (doi: 10.1136/bmjopen-2023-078539) (PMID:37770264) (PMCID:PMC10546161)
2022
Tezcan, Neslihan, Özdemir-Kumral, Zarife Nigâr, Özkan Yenal, Naziye, Çilingir-Kaya, Özlem T., Virlan, Aysin Tulunay ORCID: https://orcid.org/0000-0003-4735-9902, Özbeyli, Dilek, Çetinel, Şule, Yeğen, Berrak Ç. and Koç, Mehmet
(2022)
Nesfatin-1 treatment preserves antioxidant status and attenuates renal fibrosis in rats with unilateral ureteral obstruction.
Nephrology Dialysis Transplantation, 37(7),
pp. 1238-1248.
(doi: 10.1093/ndt/gfac053)
(PMID:35218196)
Kelly, Lauren, McGrath, Sarah, Rodgers, Lewis, McCall, Kathryn, Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Dempsey, Fiona, Crichton, Scott and Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941
(2022)
Annexin-A1: the culprit or the solution?
Immunology, 166(1),
pp. 2-16.
(doi: 10.1111/imm.13455)
(PMID:35146757)
Isaacs, J. D. et al. (2022) RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients. Scientific Data, 9(1), 196. (doi: 10.1038/s41597-022-01264-y) (PMID:35534493) (PMCID:PMC9085807)
2020
Onur Elbaşı, Mehmet, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Karagözoğlu, Hale, Kahraman, Semra and Ekşioğlu-Demiralp, Emel
(2020)
Maternal killer-cell immunoglobulin-like receptors and paternal human leukocyte antigen ligands in recurrent pregnancy loss cases in Turkey.
Clinical and Experimental Reproductive Medicine, 47(2),
pp. 122-129.
(doi: 10.5653/cerm.2019.03223)
(PMID:32450627)
(PMCID:PMC7315865)
2018
Tom, Brian D.M., Symmons, Deborah and RA-MAP Consortium: (2018) Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data. RMD Open, 4(2), e000721. (doi: 10.1136/rmdopen-2018-000721) (PMID:30487994) (PMCID:PMC6241979)
Elbasi, Mehmet Onur, Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902 and Eksioglu Demiralp, Emel
(2018)
Killer cell immunoglobulin-like receptor genotypes in the Turkish population.
Human Immunology, 79(4),
pp. 193-194.
(doi: 10.1016/j.humimm.2018.02.008)
(PMID:29454072)
2017
Betul Cakir, Fatma, Gülsün Berrak, Su, Aydogan, Gonul, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Timur, Cetin, Canpolat, Cengiz and Eksioglu Demiralp, Emel
(2017)
Effects of malnutrition on neutrophil/mononuclear cell apoptotic functions in children with acute lymphoblastic leukemia.
Nutrition and Cancer, 69(3),
pp. 402-407.
(doi: 10.1080/01635581.2017.1267778)
(PMID:28107040)
Deniz, Rabia, Tulunay-Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ture Ozdemir, Filiz, Unal, Ali Ugur, Ozen, Gulsen, Alibaz-Oner, Fatma, Aydin-Tatli, Imren, Mumcu, Gonca, Ergun, Tulin and Direskeneli, Haner
(2017)
Th17-inducing conditions lead to in vitro activation of both Th17 and Th1 responses in Behcet’s disease.
Immunological Investigations, 46(5),
pp. 518-525.
(doi: 10.1080/08820139.2017.1306865)
(PMID:28414558)
2016
Cerman, Asli Aksu, Aktas, Ezgi, Altunay, Ilknur Kivanc, Arici, Janset Erkul, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902 and Ozturk, Feyza Yener
(2016)
Dietary glycemic factors, insulin resistance, and adiponectin levels in acne vulgaris.
Journal of the American Academy of Dermatology, 75(1),
pp. 155-62.
(doi: 10.1016/j.jaad.2016.02.1220)
(PMID:27061046)
2015
Demirca, Beyza Poplata, Cagan, Hasret, Kiykim, Ayca, Arig, Ulku, Arpa, Medeni, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ozen, Ahmet, Karakoc-Aydiner, Elif, Baris, Safa and Barlan, I.B.
(2015)
Nebulized fluticasone propionate, a viable alternative to systemic route in the management of childhood moderate asthma attack: A double-blind, double-dummy study.
Respiratory Medicine, 109(9),
pp. 1120-1125.
(doi: 10.1016/j.rmed.2015.07.007)
(PMID:26216378)
Demirca, Poplata B., Cagan, H. H., Kiykim, A., Arig, U., Arpa, M., Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ozen, A., Karakoc-Aydiner, E., Baris, S. and Barlan, I.
(2015)
Nebulized fluticasone propionate, a viable alternative to systemic route in the management of childhood moderate asthma attack: a double-blind, double-dummy study.
Allergy, 70,
p. 347.
Tulunay, A. et al. (2015) Activation of the JAK/STAT pathway in Behcet's disease. Genes and Immunity, 16(2), pp. 170-175. (doi: 10.1038/gene.2014.64) (PMID:25410656) (PMCID:PMC4443896)
Sahin, Sadik, Ozakpinar, Ozlem Bingol, Eroglu, Mustafa, Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ciraci, Enver, Uras, Fikriye and Tetik, Sermin
(2015)
The impact of platelet functions and inflammatory status on the severity of preeclampsia.
Journal of Maternal-Fetal and Neonatal Medicine, 28(6),
pp. 643-648.
(doi: 10.3109/14767058.2014.927860)
(PMID:24853491)
2014
Baris, S., Kiykim, A., Ozen, A., Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Karakoc-Aydiner, E. and Barlan, I.B.
(2014)
Vitamin D as an adjunct to subcutaneous allergen immunotherapy in asthmatic children sensitized to house dust mite.
Allergy, 69(2),
pp. 246-253.
(doi: 10.1111/all.12278)
(PMID:24180595)
2013
Mumcu, Gonca, Inanc, Nevsun, Ozdemir, Filiz T., Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Eksioglu-Demiralp, Emel, Ergun, Tulin and Direskeneli, Haner
(2013)
Effects of azithromycin on intracellular cytokine responses and mucocutaneous manifestations in Behcet's disease.
International Journal of Dermatology, 52(12),
pp. 1561-1566.
(doi: 10.1111/ijd.12144)
(PMID:23879671)
Articles
Ansalone, C. et al. (2025) Spatial profiling of giant cell arteritis tissues reveals immune heterogeneity and potential predictors of glucocorticoid response. Annals of the Rheumatic Diseases, (doi: 10.1016/j.ard.2025.09.009) (PMID:41109780) (Accepted for Publication)
Wang, L. et al. (2025) Human regulatory B cells suppress autoimmune disease primarily via interleukin-37. Journal of Autoimmunity, 153, 103415. (doi: 10.1016/j.jaut.2025.103415) (PMID:40250016)
Deniz, Rabia, Tulunay-Virlan, Aysın ORCID: https://orcid.org/0000-0003-4735-9902, Ture Ozdemir, Filiz, Ugur Unal, Ali, Ozen, Gulsen, Alibaz-Oner, Fatma, Aydin-Tatli, Imren and Direskeneli, Haner
(2024)
Analysis of proinflammatory cytokine responses in Takayasu arteritis.
Archives of Rheumatology, 39(4),
pp. 598-606.
(doi: 10.46497/ArchRheumatol.2024.10790)
(PMID:40060124)
(PMCID:PMC11883268)
Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Cafaro, Giacomo, Sunzini, Flavia, Degboe, Yannick and Christodoulou, Maria-Ionna
(2024)
Editorial: immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimmunity and immune-related adverse effects.
Frontiers in Oncology, 14,
1476475.
(doi: 10.3389/fonc.2024.1476475)
(PMID:39252949)
(PMCID:PMC11381221)
Eraslan, Muhsin, Çerman, Eren, Bozkurt, Süheyla, Genç, Deniz, Tulunay Virlan, Aysın ORCID: https://orcid.org/0000-0003-4735-9902, Subaşı Demir, Cansu, Akkoç, Tolga, Karaöz, Erdal and Akkoç, Tunç
(2023)
Mesenchymal stem cells differentiate to retinal ganglion-like cells in rat glaucoma model induced by polystyrene microspheres.
Tissue and Cell, 84,
102199.
(doi: 10.1016/j.tice.2023.102199)
(PMID:37633122)
Ooms, A. et al. (2023) Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis. BMJ Open, 13(9), e078539. (doi: 10.1136/bmjopen-2023-078539) (PMID:37770264) (PMCID:PMC10546161)
Tezcan, Neslihan, Özdemir-Kumral, Zarife Nigâr, Özkan Yenal, Naziye, Çilingir-Kaya, Özlem T., Virlan, Aysin Tulunay ORCID: https://orcid.org/0000-0003-4735-9902, Özbeyli, Dilek, Çetinel, Şule, Yeğen, Berrak Ç. and Koç, Mehmet
(2022)
Nesfatin-1 treatment preserves antioxidant status and attenuates renal fibrosis in rats with unilateral ureteral obstruction.
Nephrology Dialysis Transplantation, 37(7),
pp. 1238-1248.
(doi: 10.1093/ndt/gfac053)
(PMID:35218196)
Kelly, Lauren, McGrath, Sarah, Rodgers, Lewis, McCall, Kathryn, Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Dempsey, Fiona, Crichton, Scott and Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941
(2022)
Annexin-A1: the culprit or the solution?
Immunology, 166(1),
pp. 2-16.
(doi: 10.1111/imm.13455)
(PMID:35146757)
Isaacs, J. D. et al. (2022) RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients. Scientific Data, 9(1), 196. (doi: 10.1038/s41597-022-01264-y) (PMID:35534493) (PMCID:PMC9085807)
Onur Elbaşı, Mehmet, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Karagözoğlu, Hale, Kahraman, Semra and Ekşioğlu-Demiralp, Emel
(2020)
Maternal killer-cell immunoglobulin-like receptors and paternal human leukocyte antigen ligands in recurrent pregnancy loss cases in Turkey.
Clinical and Experimental Reproductive Medicine, 47(2),
pp. 122-129.
(doi: 10.5653/cerm.2019.03223)
(PMID:32450627)
(PMCID:PMC7315865)
Tom, Brian D.M., Symmons, Deborah and RA-MAP Consortium: (2018) Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data. RMD Open, 4(2), e000721. (doi: 10.1136/rmdopen-2018-000721) (PMID:30487994) (PMCID:PMC6241979)
Elbasi, Mehmet Onur, Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902 and Eksioglu Demiralp, Emel
(2018)
Killer cell immunoglobulin-like receptor genotypes in the Turkish population.
Human Immunology, 79(4),
pp. 193-194.
(doi: 10.1016/j.humimm.2018.02.008)
(PMID:29454072)
Betul Cakir, Fatma, Gülsün Berrak, Su, Aydogan, Gonul, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Timur, Cetin, Canpolat, Cengiz and Eksioglu Demiralp, Emel
(2017)
Effects of malnutrition on neutrophil/mononuclear cell apoptotic functions in children with acute lymphoblastic leukemia.
Nutrition and Cancer, 69(3),
pp. 402-407.
(doi: 10.1080/01635581.2017.1267778)
(PMID:28107040)
Deniz, Rabia, Tulunay-Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ture Ozdemir, Filiz, Unal, Ali Ugur, Ozen, Gulsen, Alibaz-Oner, Fatma, Aydin-Tatli, Imren, Mumcu, Gonca, Ergun, Tulin and Direskeneli, Haner
(2017)
Th17-inducing conditions lead to in vitro activation of both Th17 and Th1 responses in Behcet’s disease.
Immunological Investigations, 46(5),
pp. 518-525.
(doi: 10.1080/08820139.2017.1306865)
(PMID:28414558)
Cerman, Asli Aksu, Aktas, Ezgi, Altunay, Ilknur Kivanc, Arici, Janset Erkul, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902 and Ozturk, Feyza Yener
(2016)
Dietary glycemic factors, insulin resistance, and adiponectin levels in acne vulgaris.
Journal of the American Academy of Dermatology, 75(1),
pp. 155-62.
(doi: 10.1016/j.jaad.2016.02.1220)
(PMID:27061046)
Demirca, Beyza Poplata, Cagan, Hasret, Kiykim, Ayca, Arig, Ulku, Arpa, Medeni, Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ozen, Ahmet, Karakoc-Aydiner, Elif, Baris, Safa and Barlan, I.B.
(2015)
Nebulized fluticasone propionate, a viable alternative to systemic route in the management of childhood moderate asthma attack: A double-blind, double-dummy study.
Respiratory Medicine, 109(9),
pp. 1120-1125.
(doi: 10.1016/j.rmed.2015.07.007)
(PMID:26216378)
Demirca, Poplata B., Cagan, H. H., Kiykim, A., Arig, U., Arpa, M., Tulunay, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ozen, A., Karakoc-Aydiner, E., Baris, S. and Barlan, I.
(2015)
Nebulized fluticasone propionate, a viable alternative to systemic route in the management of childhood moderate asthma attack: a double-blind, double-dummy study.
Allergy, 70,
p. 347.
Tulunay, A. et al. (2015) Activation of the JAK/STAT pathway in Behcet's disease. Genes and Immunity, 16(2), pp. 170-175. (doi: 10.1038/gene.2014.64) (PMID:25410656) (PMCID:PMC4443896)
Sahin, Sadik, Ozakpinar, Ozlem Bingol, Eroglu, Mustafa, Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Ciraci, Enver, Uras, Fikriye and Tetik, Sermin
(2015)
The impact of platelet functions and inflammatory status on the severity of preeclampsia.
Journal of Maternal-Fetal and Neonatal Medicine, 28(6),
pp. 643-648.
(doi: 10.3109/14767058.2014.927860)
(PMID:24853491)
Baris, S., Kiykim, A., Ozen, A., Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Karakoc-Aydiner, E. and Barlan, I.B.
(2014)
Vitamin D as an adjunct to subcutaneous allergen immunotherapy in asthmatic children sensitized to house dust mite.
Allergy, 69(2),
pp. 246-253.
(doi: 10.1111/all.12278)
(PMID:24180595)
Mumcu, Gonca, Inanc, Nevsun, Ozdemir, Filiz T., Tulunay Virlan, Aysin ORCID: https://orcid.org/0000-0003-4735-9902, Eksioglu-Demiralp, Emel, Ergun, Tulin and Direskeneli, Haner
(2013)
Effects of azithromycin on intracellular cytokine responses and mucocutaneous manifestations in Behcet's disease.
International Journal of Dermatology, 52(12),
pp. 1561-1566.
(doi: 10.1111/ijd.12144)
(PMID:23879671)