Professor Andy Waters

  • Professor in Biomedical and Life Sciences (Parasitology)
  • Associate - Life Sciences (School of Life Sciences)

telephone: 01413308720
email: Andy.Waters@glasgow.ac.uk

Research interests

Prof Waters has >30 years experience in malaria research and together with Dr Chris Janse helped pioneer the development of the rodent model of malaria research, Plasmodium berghei in Leiden. He is a Wellcome Trust Principal Research Fellow with current funding until 2021. The major objective of the Glasgow laboratory is to understand the molecular developmental biology that is associated with sexual development.

There are three main themes to the research:

1. Triggers for gametocytogenesis. A transcription factor underpinning commitment to this critical event has been recently identified in the laboratory (Sinha et al (2014) Nature).  Its mode of action and control of its expression are currently under study.

2.  Influence of host environment on parasite development. This is an interest largely driven by metabolomics and seeks to understand the resources available to the intracellular parasite and the consequences of those resources for drug development and parasite maturation.

3. Development of tools for the more sophisticated genetic engineering of malaria parasites

The laboratory analyses these issues using a polyomics approach which is institutionalised in Glasgow and includes: metabolomics, NGS, proteomics, parasite genetic manipulation and complemented by a fully functioning insectary.  Technology development is also a key part of our activities where we have recently developed three new approaches to inducible regulation of gene/protein expression with a view to assigning function to genes/proteins

Our laboratory currently has four post-doctoral researchers with a great range of molecular biological expertise, four technical support staff and four PhD students.  Our activities are complemented by three other research groups working on malaria or Toxoplasma and through our participation in the WTCMP of which Prof Waters is Director.  Together with the many other parasitological groups at Glasgow there is the greatest concentration and breadth of molecular parasitology expertise in the UK. Prof. Waters was also Scientific Director of Evimalar, a European Commission-funded Network of Excellence that improved European and global collaboration in the basic research of malaria parasite biology and their interactions with their hosts and vectors.  Evimalar has now devolved to form Evimalar EEIG (European Economic Interest Group) which contains 13 founder members and can partner traditional institutions in bids for international funding.

 

Our Group:

PPDRAs and Fellows

Dr Nisha Philip has extensive experience in signalling and miRNAs in Plasmodium and has recently developed an inducible protein degradation systems (Philip & Waters, 2015)

Dr Katie Hughes has extensive experience in Plasmodium cell biology and protozoan molecular biology. 

Dr Brett Roberts has just joined the laboratory and will focus on parasite genetic manipulation.

Dr Sebastian Kirchner is a Marie Curie International Fellow studying epigenetic regulation of Plasmodium gene expression.

PhD students: thesis titles.

Ms Rebecca Lee: “The Natural History of Plasmodium Gametocytes”

Ms Robyn Kent: “Experimentally Inducible Gametocytogenesis in Plasmodium”

Ms Joanne Power; “ Epigenetics and Gametocytogenesis in Plasmodium”

There is currently a vacancy for an experienced bioinformatician.

The Tech Team

Ms Anne Graham is the Laboratory Manager and responsible for the co-ordination of the laboratory activities.  She has extensive experience in molecular biology.

Ms Heli Vaikinnen has extensive experience in the molecular biology of protozoan parasites.

Mrs Angela McBride runs the group’s insectary facility Mr John Archer has expertise in informatics and parasitology

Updated: 4.11.2015

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Blantyre-Blantyre Clinical Research Project
    The Scottish Government
    2017 - 2022
     
  • Gene expression in Plasmodium parasites: the molecular mechanics of gametocytogenesis (and variant transcription of genes)
    Wellcome Trust
    2016 - 2021
     
  • Stage differentiation in malaria parasites
    Royal Society
    2016 - 2021
     
  • Role of sub-activation-threshold TCR interactions in maintaining T cell memory
    National Institute of Health
    2015 - 2016
     
  • SECOMAP
    European Commission
    2015 - 2017
     
  • Identification and analysis of essential proteins involved in Toxoplasma gondii mitochondrial tRNA import (ISSF Fellowship)
    Wellcome Trust
    2015 - 2015
     
  • Biology and Pathology of the Malaria Parasite
    The Company Biologists Limited
    2014 - 2015
     
  • Role of sub-activation-threshold TCR interactions in maintaining T cell memory
    National Institute of Health
    2014 - 2015
     
  • Institutional Strategic Support Fund (ISSF)
    Wellcome Trust
    2014 - 2017
     
  • The Wellcome Centre for Molecular Parasitology ( Core Support )
    Wellcome Trust
    2014 - 2021
     
  • Institutional Strategic Support Fund (ISSF)
    Wellcome Trust
    2013 - 2014
     
  • Funding Schemes
    Wellcome Trust
    2013 - 2014
     
  • Wellcome Trust Liverpool-Glasgow Centre for Global Health Research
    Wellcome Trust
    2013 - 2018
     
  • Institutional Strategic Support Fund (ISSF)
    Wellcome Trust
    2012 - 2014
     
  • ParaMet - A systematic approach to understanding parasite metabolism.
    European Commission
    2012 - 2016
     
  • Ozmalnet⌒TOWARDS THE ESTABLISHMENT OF A FRAMEWORK IN MALARIA BETWEEN THE AMRN AND EVIMALAR
    European Commission
    2012 - 2014
     
  • Integrated Health - Polyomics and Systems Biomedicine (ISSF Bid)
    Wellcome Trust
    2011 - 2014
     
  • RSE International Exhange Programme: IEP Open - Incoming
    Royal Society of Edinburgh
    2010 - 2010
     
  • Evimalar
    European Commission
    2009 - 2014
     
  • Conditional translational repression: a core regulatory mechanism of gene expression during development of the malaria parasite.
    Wellcome Trust
    2008 - 2015
     
  • Search for optimised inhibitors of Plasmodium falciparum
    Medicines for Malaria Venture
    2008 - 2008
     

Additional information

Editorial Board

  • 2005 - ongoing: Future Microbiology - Member Editorial Advisory Board
  • 2001 - ongoing: Molecular & Biochemical Parasitology - Executive Editor
  • 2000 - 2005: Molecular & Biochemical Parasitology - Member Editorial Board & Reviews Editor
  • 1998 - 2008: Trends in Parasitology - Member Editorial Advisory Board

Grant Advisory Board

  • 2013 - ongoing: Center of Infection and Immunity of Lille, France - Committee member for external evaluation of Center of Infection and Immunity of Lille for Agence d'Evaluation de la Recherche et des etablissements d'Enseignement Superieur (AERES)
  • 2013 - 2017: Wellcome Trust Sanger Institute - Malaria Programme Scientific Advisory Board Member
  • 2013 - ongoing: Institute Cochin, Paris, France - Committee member for external evaluation of Department of Infection, Immunology & Inflammation for Agence d'Evaluation de la Recherche et des etablissements d'Enseignement Superieur (AERES)
  • 2012 - ongoing: Glasgow, Scotland, UK - Co-Organiser, Glasgow Polyomics International Symposium
  • 2012 - ongoing: German Research Foundation (DFG), Bonn, Germany - Invited Expert Reviewer by DFG in the field of Immunology, Inflammation & Infection Biology
  • 2012 - ongoing: Wellcome Trust/Royal Society - Member of the Interview Panel for the Wellcome Trust/Royal Society Sir Henry Dale Fellowships
  • 2011 - ongoing: NIH Bethesda, Maryland, USA - Invited expert reviewer of proposals received in response to RFP-NIAID-DMID-NIH-AI2010100 entitled: "An Integrated Approach to Understanding Host-Pathogens Interactions"
  • 2010 - ongoing: Wellcome Trust Expert Group - Member, Malaria 1990 to date: key influences & the role of the Wellcome Trust
  • 2009 - 2014: Biomalpar - Director Biomalpar, a European Community-funded Network of Excellence
  • 2007 - 2007: WHO/TDR - Consultant to Steering Committee on Pathogenesis and Applied Genomics
  • 2007 - 2007: International Livestock Research Institute (ILRI) - Consultant on development of anti-parasitic diagnostics and vaccines in the post-genomic era
  • 2007 - 2007: Wellcome Trust - Member External review Committee for PhD Programme
  • 2006 - 2008: WHO/TDR - PLUS Review panel member for parasite applied genomics
  • 2006 - 2008: Nederlandse Organisatie voor Wetenschappelijke Onderzoek (NWO) - Rubicon award, review panel member
  • 2006 - 2006: French Medical Research Council (INSERM) - Appointed INSERM expert peer reviewer
  • 2006 - 2009: European ANTIMAL Network - Member of External Scientific Advisory Committee
  • 2005 - 2010: WHO - Member Parasite Transfection Task Force and Drug Resistance
  • 2004 - 2009: European Commission Framework VI - Member Executive Scientific Steering Committee and Scientific Cluster Co-ordinator, Network of Excellence, Biology of Malaria Parasites (BIOMALPAR)
  • 2002 - 2005: The Malaria Research and Reference Reagent Resource Center (MR4) - Member Scientific Advisory Panel, MR4, ATCC, Manassas, VA, USA
  • 2001 - 2001: Institut Pasteur - Member, External Evaluation Committee, Department of Immunology
  • 2001 - 2004: Wellcome Trust - Member, Infection & Immunity Panel
  • 2001 - 2007: Nederlandse Organisatie voor Wetenschappelijke Onderzoek (NWO) - Member, Microbiology Grants Panel, Aard-en Levenswetenschappen (ALW)

Invited International Presentations

  • 2014: Heidelberg, Germany - Invited Speaker, Biomalpar 10, The Annual Evimalar Meeting, EMBL
  • 2014: Hinxton, England, UK - Invited Speaker and Tutor, Advanced Course on Parasite Genetics, Wellcome Trust Sanger Institute
  • 2014: Nijmegen, The Netherlands - Invited Speaker, Department of Molecular Biology, Radboud University Medical Centre
  • 2013: Berkhamsted, England, UK - Invited Speaker, 2nd Wellcome Trust Researcher Meeting
  • 2013: San Feliu de Guixols, Spain - Invited Speaker: Comparative Genomics of Eukaryotic Microorganisms: Patterns of Complexity in Eukaryotic Genomes
  • 2013: Lucca, Italy - Invited Speaker, Gordon Conference on Malaria
  • 2013: Snowmass, Colorado, USA - Invited Speaker, FASEB Summer Research Conference "Microbial Pathogenesis: Mechanisms of Infectious Disease"
  • 2013: New Orleans, Louisiana (USA) - Co-organiser and speaker, Keystone meeting, Malaria
  • 2012: Lille, France - Invited Speaker, Molecular Parasitology Symposium, Institute Pasteur
  • 2012: London, England, UK - Invited Speaker, Inaugural Wellcome Trust Researcher Meeting
  • 2012: Glasgow, Scotland, UK - Co-organiser & speaker, Introduction to Metabolomics, an Evimalar Training Course
  • 2012: Warwick, England, UK - Symposium Organiser, "Molecular Motors" SGM Autumn Meeting
  • 2012: Hinxton, England, UK - Invited speaker and tutor, Advanced Course on Parasite Genetics, Wellcome Trust Sanger Institute
  • 2012: Lorne, Victoria, Australia - Invited Speaker and member of International Scientific Organising Committee, "Molecular Approaches to Malaria" Conference
  • 2012: Santa Fe, New Mexico, USA - Invited plenary speaker, Joint Keystone Symposia on Drug Discovery for Protozoan Parasites/Fungal Pathogens: From Basic Biology to Drug Discovery
  • 2011: Philadelphia, Pennsylvania, USA - Invited Speaker, Department of Microbiology, University of Pennsylvania School of Medicine
  • 2011: Guaruja, Brazil - Member of the International Scientific Committee, Symposium Chair and Speaker, of the 1st International Meeting on Cell Biology of Pathogens (IMCBP) joint with American Society of Cell Biology (ASCB)
  • 2011: Bethesda, Maryland, USA - Invited Speaker, "Gametocyte Biology", Sponsored by MIH and Gates Foundation
  • 2010: Kampala, Uganda - Invited lecturer, Genes & Genomes in the Tropics, an Evimalar sponsored course, University of Kampala
  • 2010: Edinburgh, Scotland, UK - Invited Speaker, "Parasite to prevention: Advances in the understanding of malaria, a Biomed Central Conference
  • 2010: Heidelberg, Germany - Invited Speaker, EMBO Fellows Inaugural Conference
  • 2010: Melbourne, Australia - Symposium Chair (x2) & Invited Speaker (x3), ICOPA XII
  • 2010: BPRC - Invited Speaker, Laudatio for Dr Alan Thomas
  • 2010: Heidelberg, Germany - Organiser 6th Biomalpar conference
  • 2010: Edinburgh, Scotland, UK - Symposium co-organiser and chair (with Dr. M. Ginger), Society for General Microbiology AGM
  • 2010: Hinxton, England, UK - Invited Speaker, Wellcome Trust Sanger Centre
  • 2009: Woods Hole, Massachusetts, USA - Invited Speaker, Biology of Parasitism
  • 2009: Aberdeen, Scotland, UK - Invited Speaker, University of Aberdeen, Department of Medical Microbiology
  • 2009: Oxford, England, UK - Invited Speaker, Malaria Gordon Conference
  • 2009: Baltimore, Maryland, USA - Invited Speaker, 7th Malaria Conference of the Malaria Institute, Johns Hopkins University
  • 2008: Lorne, Australia - Invited Speaker, 3rd MAM Conference
  • 2008: Singapore - Invited Speaker, 2nd Malaria Conference, Nangyang TU
  • 2008: Melbourne, Australia - Invited Speaker, Genome Technology Access Centre (GTAC), presentation made to an invited audience of High School students
  • 2008: Woods Hole, Massachusetts, USA - Invited Speaker, Biology of Parasitism
  • 2008: Brussels, Belgium - White paper author and rapporteur at "Challenges for the Future: Research on HIV/AIDS, Malaria and Tuberculosis" FP7 policy conference for FP8
  • 2008: Alpbach, Austria - Invited Speaker Keystone Symposium on Malaria: Immunology, Pathogenesis and Vaccine Perspectives
  • 2008: Rhode Island, USA - Invited Speaker, Gordon Research Conference on the Biology of Host-Parasite Interactions
  • 2007: San Feliu de Guixols, Spain - Invited Speaker, 2nd ESF-EMBO Symposium Comparative Genomics of Eukaryotic Microorganisms: "Eukaryotic Genome Evolution from Yeasts to Parasites and Pathogens"
  • 2007: Leiden, The Netherlands - Invited speaker, Centre of Infectious Diseases symposium, Leiden University Medical Centre
  • 2007: Woods Hole, Massachusetts, USA - Invited Speaker, Biology of Parasitism Course, MBL
  • 2007: Bern, Switzerland - Invited Speaker, University of Bern Graduate School Cell Biology
  • 2007: Arnhem, The Netherlands - Invited Speaker, Dutch Microbiology Society Annual Meeting
  • 2007: Bangkok, Thailand - Course Faculty, Malaria Parasite Transfection Workshop
  • 2007: Siena, Italy - Invited Speaker 1st Global Novartis Infectious Disease Meeting
  • 2007: St. Louis, Missouri, USA - Invited Speaker, Department of Microbiology, Washington University
  • 2007: Salvador, Bahia, Brazil - Invited Speaker, XXXVI Annual Meeting of the Brazilian Society of Biochemistry and Molecular Biology (SBBq)
  • 2006: Puerto Rico - Invited Speaker, University of Puerto Rico
  • 2006: Glasgow, Scotland, UK - Invited Speaker, University of Glasgow, Division of Life Sciences
  • 2006: Woods Hole, Massachusetts, USA - Invited Speaker, Biology of Parasitism Course, MBL
  • 2006: Woods Hole, Massachusetts, USA - Co-organiser, Molecular Parasitology Meeting
  • 2006: Jerusalem, Israel - Invited Speaker, workshop on Severe Malaria, Israeli Society for Parasitology, Protozoology and Tropical Diseases (ISPPTD)
  • 2006: Dresden, Germany - Speaker, COST 857 Conference
  • 2006: Rhode Island, USA - Invited Speaker, Gordon Research Conference on the Biology of Host-Parasite Interactions
  • 2006: Glasgow, Scotland, UK - Invited Speaker, University of Glasgow, Division of Life Sciences
  • 2006: Matsuyama, Japan - Invited Speaker, Matsuyama International Symposium on Cell-Free Sciences
  • 2006: Leiden, The Netherlands - Invited Speaker, Federation of Biomedical Scientific Societies (FMWV-NWO)
  • 2006: Atlanta, Georgia, USA - Invited Speaker, "Knockouts (and knock-ins) in parasites: promises and challenges" pre-meeting workshop, American Society of Tropical Medicine and Hygiene (ASTMH) meeting
  • 2006: Heidleberg, Germany - Lead organiser, EU FP6 NoE BIOMALPAR Annual Meeting
  • 2006: Singapore - External Examiner, Thesis Jaysree Iyer, University of Nan-Yang
  • 2006: Dundee, Scotland, UK - Invited Speaker, University of Dundee
  • 2006: Taos, New Mexico, USA - Invited Speaker, Keystone Symposium on Malaria: Functional Genomics to Biology to Medicine
  • 2005: New Delhi, India - Course Faculty, Malaria Parasite Transfection Workshop
  • 2005: Veyrier du Lac, France - Invited Panelist, "Future of Anti-Parasitic Vaccines" meeting, Merieux Foundation
  • 2005: Woods Hole, Massachusetts, USA - Invited Speaker, Biology of Parasitism course
  • 2005: San Feliu de Guixols, Spain - Invited Speaker ESF-EMBO Conference, Comparative genomics of eukaryotic microorganisms: eukaryotic genome evolution, approaches with yeasts and fungi
  • 2005: Oxford, England, UK - Organiser and Chair, Gordon Research Conference on Malaria
  • 2005: Boston, Massachusetts, USA - Invited participant, "Future of Malaria Genomics", Policy forum sponsored by Burroughs Wellcome Fund and Wellcome Trust
  • 2005: Woods Hole, Massachusetts, USA - Co-organiser, Molecular Parasitology Meeting
  • 2005: Washington, DC, USA - Invited Speaker, Plasmodium pre-erythrocytic development; genomic/proteomic approaches to intervention
  • 2004: Paris, France - Invited Speaker at "Dynamic Imaging Microscopy & Analysis for Biologists" Workshop, Institut Pasteur
  • 2004: Lorne, Australia - Speaker & Session Chair, MAM04
  • 2004: Chester, England, UK - Invited Keynote Speaker, British Society for Parasitology, Annual meeting
  • 2004: Les Treilles, France - Invited participant in New Frontiers in Malaria Parasite and Anopheles Mosquito Engineering, Fondation des Treilles
  • 2004: Woods Hole, Massachusetts, USA - Invited Speaker, Biology of Parasitism course
  • 2004: Bangkok, Thailand - Invited Speaker and Discussant, WHO Workshop, "The impact of genetic engineering of Plasmodium on parasite drug resistance"
  • 2004: Miami, Florida, USA - Invited Speaker, Symposium on "Transmission Blocking Vaccines", ASTMH Meeting
  • 2004: London, England, UK - Invited Speaker, Keynote Lecture Series, NIMR, Mill Hill
  • 2004: Singapore - Invited Speaker, Molecular Approaches to Malaria, Nanyang Technological University, Singapore
  • 2004: Baltimore, Maryland, USA - Invited Speaker, 2nd Malaria Conference of the Malaria Institute, Johns Hopkins University
  • 2004: Melbourne, Australia - Invited speaker at Walter and Elisa Hall Institute
  • 2004: Woods Hole, Massachusetts, USA - Co-organiser, Molecular Parasitology Meeting
  • 2003: Aubiere, France - Plenary Speaker, Bienniale Reunion Protozologists
  • 2003: Amsterdam, The Netherlands - Symposium speaker, Phacilitate Vaccine development Congress
  • 2003: Kindrogan, Scotland, UK - British Society for Parasitology Kindrogan Speaker, SUMP
  • 2003: Edinburgh, Scotland, UK - Invited speaker, University of Edinburgh
  • 2003: Heidelberg, Germany - Invited speaker, ZDF Spearpoint programme, University of Heidelberg
  • 2003: Paris, France - Plenary Speaker, European Conference on Computational Biology 2003
  • 2003: Glasgow, Scotland, UK - Invited Speaker, Wellcome Institute for Parasitology Lecture Series, University of Glasgow
  • 2003: Manchester, England - Symposium speaker, "Post Genomics Applied to Processes: Advances in Eukaryotic Microbiology", Society for General Microbiology
  • 2003: Oxford, England, UK - Vice chairman, Gordon Research Conference on Malaria
  • 2003: Utrecht, The Netherlands - Invited Speaker, Dutch Microbiological Society, de Uithof
  • 2003: Odense, Denmark - Invited Speaker, University of Southern Denmark
  • 2002: Tucson, Arizona, USA - Invited speaker, Vector Pathogen interactions meeting
  • 2002: Woods Hole, Massachusetts, USA - Session Chair, Molecular Parasitology Meeting
  • 2002: Woods Hole, Massachusetts, USA - Invited speaker, Molecular Parasitology Course
  • 2002: Kindrogan, Scotland, UK - Plenary speaker, SUMP
  • 2002: Stockholm, Sweden - Invited Speaker, Pathology of Malaria, Meeting, Karolinska Institute
  • 2002: Umea, Sweden - Speaker, external lecture series, University of Umea
  • 2001: Keele, England, UK - Plenary Speaker, British Society for Parasitology
  • 2001: London, England, UK - Invited Speaker, "Functional Genomics of Protozoan Parasites", Royal Society of Great Britain
  • 2001: Hinxton, England, UK - Invited participant, 11th Malaria Genome Meeting, Wellcome Trust
  • 2001: Woods Hole, Massachusetts, USA - Invited speaker, Molecular Parasitology Course
  • 2001: Oxford, England, UK - Invited speaker, Gordon Malaria Conference

Prizes, Awards and Distinctions

  • 2010: Royal Society of Edinburgh - Elected Fellow
  • 2009: European Virtual Institute for Malaria Research (Evimalar) - Director, Evimalar
  • 2009: European Molecular Biology Organisation - Elected member
  • 2008: Wellcome Trust - Principal Research Fellow
  • 2006: Edinburgh, Scotland, UK - Visiting Professor, University of Edinburgh
  • 2003: London, England, UK - Honorary Reader, Imperial College
  • 2001: Oeiras, Portugal - Visiting Fellow, Gulbenkian Institute of Science

Professional Learned Society

  • 2010 - ongoing: Royal Society of Edinburgh - Fellow
  • 2009 - ongoing: European Molecular Biology Organisation - Elected Member
  • 2009 - ongoing: Society for General Microbiology
  • 2000 - 2008: British Society for Parasitology
  • 1998 - 2007: Dutch Parasitological Society (NVP)
  • 1996 - 2001: Royal Society of Tropical Medicine and Hygiene

Research Fellowship

  • 2008 - 2015: Wellcome Trust Principal Research Fellowship

Publications

List by: Type | Date

Jump to: 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008
Number of items: 60.

2017

Waters, A.P. and Bechtsi, D.P. (2017) Genomics and epigenetics of sexual commitment in Plasmodium. International Journal for Parasitology, 47(7), pp. 425-434. (doi:10.1016/j.ijpara.2017.03.002) (PMID:28455236)

Hughes, K. R. and Waters, A. P. (2017) Rapid inducible protein displacement in Plasmodiumin vivo and in vitro using knocksideways technology. Wellcome Open Research, 2, 18. (doi:10.12688/wellcomeopenres.11005.1) (PMID:28428983) (PMCID:PMC5395084)

2016

Srivastava, A., Philip, N., Hughes, K. R., Georgiou, K., MacRae, J. I., Barrett, M. P. , Creek, D. J., McConville, M. J. and Waters, A. P. (2016) Stage-specific changes in plasmodium metabolism required for differentiation and adaptation to different host and vector environments. PLoS Pathogens, 12(12), e1006094. (doi:10.1371/journal.ppat.1006094) (PMID:28027318) (PMCID:PMC5189940)

Kirchner, S., Power, B. J. and Waters, A. P. (2016) Recent advances in malaria genomics and epigenomics. Genome Medicine, 8, 92. (doi:10.1186/s13073-016-0343-7) (PMID:27605022) (PMCID:PMC5015228)

Fairlamb, A. H., Gow, N. A.R., Matthews, K. R. and Waters, A. P. (2016) Drug resistance in eukaryotic microorganisms. Nature Microbiology, 1, 16092. (doi:10.1038/nmicrobiol.2016.92) (PMID:27572976) (PMCID:PMC5215055)

Kenthirapalan, S., Waters, A. P., Matuschewski, K. and Kooij, T. W. A. (2016) Functional profiles of orphan membrane transporters in the life cycle of the malaria parasite. Nature Communications, 7, 10519. (doi:10.1038/ncomms10519) (PMID:26796412) (PMCID:PMC4736113)

Waters, A. (2016) Epigenetic roulette in blood stream plasmodium: gambling on sex. PLoS Pathogens, 12(2), e1005353. (doi:10.1371/journal.ppat.1005353) (PMID:26866803) (PMCID:PMC4750958)

2015

Philip, N. and Waters, A. P. (2015) Conditional degradation of plasmodium calcineurin reveals functions in parasite colonization of both host and vector. Cell Host and Microbe, 18(1), pp. 122-131. (doi:10.1016/j.chom.2015.05.018) (PMID:26118994) (PMCID:PMC4509507)

Srivastava, A., Creek, D. J., Evans, K. J., De Souza, D., Schofield, L., Muller, S., Barrett, M. P., McConville, M. J. and Waters, A. P. (2015) Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites. PLoS Pathogens, 11(6), e1004882. (doi:10.1371/journal.ppat.1004882) (PMID:26042734) (PMCID:PMC4456406)

Tampaki, Z., Mwakubambanya, R. S., Goulielmaki, E., Kaforou, S., Kim, K., Waters, A. P., Carruthers, V. B., Siden-Kiamos, I., Loukeris, T. G. and Koussis, K. (2015) Ectopic expression of a Neospora caninum Kazal type inhibitor triggers developmental defects in Toxoplasma and Plasmodium. PLoS ONE, 10(3), e0121379. (doi:10.1371/journal.pone.0121379) (PMID:25803874) (PMCID:PMC4372514)

2014

Otto, T. D. et al. (2014) A comprehensive evaluation of rodent malaria parasite genomes and gene expression. BMC Biology, 12(1), p. 86. (doi:10.1186/s12915-014-0086-0) (PMID:25359557) (PMCID:PMC4242472)

Religa, A., Ramesar, J., Janse, C. J., Scherf, A. and Waters, A. P. (2014) P. berghei telomerase subunit TERT is essential for parasite survival. PLoS ONE, 9(10), e108930. (doi:10.1371/journal.pone.0108930)

Frischknecht, F., Mota, M., Scherf, A. and Waters, A. (2014) Biology of the Malaria Parasite - editorial on the special issue for the 10th BioMalPar conference. Cellular Microbiology, 16(5), pp. 599-601. (doi:10.1111/cmi.12295)

Sinha, A. et al. (2014) A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium. Nature, 507(7491), pp. 253-257. (doi:10.1038/nature12970) (PMID:24572359) (PMCID:PMC4105895)

Kenthirapalan, S., Waters, A. P., Matuschewski, K. and Kooij, T. W. A. (2014) Copper-transporting ATPase is important for malaria parasite fertility. Molecular Microbiology, 91(2), pp. 315-325. (doi:10.1111/mmi.12461)

2013

Philip, N. and Waters, A. P. (2013) Unveiling the malaria parasite's cloak of invisibility? Science, 340(6135), pp. 936-937. (doi:10.1126/science.1239146)

Lin, J.-W. et al. (2013) Loss-of-function analyses defines vital and redundant functions of the plasmodiumrhomboid protease family. Molecular Microbiology, 88(2), pp. 318-338. (doi:10.1111/mmi.12187)

Philip, N., Orr, R. and Waters, A.P. (2013) Transfection of rodent malaria parasites. Methods in Molecular Biology, 923, pp. 99-125.

Waters, A.P. (2013) EVIMalaR — a model for international cooperation in scientific research. Nature Reviews Microbiology, 11(8), pp. 505-506. (doi:10.1038/nrmicro3079)

2012

Kenthirapalan, S., Waters, A.P., Matuschewski, K. and Kooij, T.W. (2012) Flow cytometry-assisted rapid isolation of recombinant Plasmodium berghei parasites exemplified by functional analysis of aquaglyceroporin. International Journal for Parasitology, 42(13-14), pp. 1185-1192. (doi:10.1016/j.ijpara.2012.10.006)

Religa, A.A. and Waters, A.P. (2012) Sirtuins of parasitic protozoa: in search of function(s). Molecular and Biochemical Parasitology, 185(2), pp. 71-88. (doi:10.1016/j.molbiopara.2012.08.003)

Reboud, J., Bourquin, Y., Wilson, R., Pall, G.S., Jiwaji, M., Pitt, A.R., Graham, A., Waters, A.P. and Cooper, J.M. (2012) Shaping acoustic fields as a toolset for microfluidic manipulations in diagnostic technologies. Proceedings of the National Academy of Sciences of the United States of America, 109(38), pp. 15162-15167. (doi:10.1073/pnas.1206055109)

Crabb, B. S., Beeson, J. G., Amino, R., Ménard, R., Waters, A., Winzeler, E. A., Wahlgren, M., Fidock, D. A. and Nwaka, S. (2012) Perspectives: the missing pieces. Nature, 484(7395), S22-S23. (doi:10.1038/484S22a)

Khan, S. M., Reece, S. E., Waters, A. P., Janse, C. J. and Kaczanowski, S. (2012) Why are male malaria parasites in such a rush?: Sex-specific evolution and host-parasite interactions. Evolution, Medicine, and Public Health, 2013(1), pp. 3-13. (doi:10.1093/emph/eos003) (PMID:24481180) (PMCID:PMC4183958)

Orr, R.Y., Philip, N. and Waters, A.P. (2012) Improved negative selection protocol for Plasmodium berghei in the rodent malarial model. Malaria Journal, 11(103), (doi:10.1186/1475-2875-11-103)

Philip, N., Vaikkinen, H.J., Tetley, L. and Waters, A.P. (2012) A unique kelch domain phosphatase in plasmodium regulates ookinete morphology, motility and invasion. PLoS ONE, 7(9), e44617. (doi:10.1371/journal.pone.0044617)

Ramakrishnan, C., Rademacher, A., Soichot, J., Costa, G., Waters, A.P., Janse, C.J., Ramesar, J., Franke-Fayard, B.M. and Levashina, E.A. (2012) Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes. PLoS ONE, 7(5), e36376. (doi:10.1371/journal.pone.0036376)

2011

Laurentino, E.C. et al. (2011) Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility. Cellular Microbiology, 13(12), pp. 1956-1974. (doi:10.1111/j.1462-5822.2011.01683.x)

Fonager, J., Franke-Fayard, B.M.D., Adams, J.H., Ramesar, J., Klop, O., Khan, S.M., Janse, C.J. and Waters, A.P. (2011) Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites. BMC Genomics, 12(155), pp. 1-17. (doi:10.1186/1471-2164-12-155)

Gomes-Santos, C.S.S. et al. (2011) Transition of plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein pumilio. PLoS Pathogens, 7(5), e1002046. (doi:10.1371/journal.ppat.1002046)

Hills, T., Srivastava, A., Ayi, K., Wernimont, A.K., Kain, K., Waters, A.P., Hui, R. and Pizarro, J.C. (2011) Characterization of a new phosphatase from Plasmodium. Molecular and Biochemical Parasitology, 179(2), pp. 69-79. (doi:10.1016/j.molbiopara.2011.06.001)

Sicard, A. et al. (2011) Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes. Cellular Microbiology, 13(6), pp. 836-845. (doi:10.1111/j.1462-5822.2011.01582.x)

Wykes, M.N. et al. (2011) Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11205-11210. (doi:10.1073/pnas.1108579108)

2010

Hughes, K.R., Philip, N., Lucas Starnes, G., Taylor, S. and Waters, A.P. (2010) From cradle to grave: RNA biology in malaria parasites. Wiley Interdisciplinary Reviews: RNA, 1(2), pp. 287-303. (doi:10.1002/wrna.30)

van Dijk, M.R. et al. (2010) Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility. PLoS Pathogens, 6(6), e1000853. (doi:10.1371/journal.ppat.1000853)

Iwanaga, S., Khan, S.M., Kaneko, I., Christodoulou, Z., Newbold, C.N., Yuda, M., Janse, C.J. and Waters, A.P. (2010) Functional identification of the Plasmodium centromere and generation of a Plasmodium artificial chromosome. Cell Host and Microbe, 7(3), pp. 245-255. (doi:10.1016/j.chom.2010.02.010)

Starnes, G. L. and Waters, A.P. (2010) Home improvements: how the malaria parasite makes the red blood cell home sweet home. Journal of Molecular Cell Biology, 2(1), pp. 11-13. (doi:10.1093/jmcb/mjp024)

Bopp, S.E.R. et al. (2010) Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-γ as contributing to enhanced malaria surviva. PLoS ONE, 5(5), e10903. (doi:10.1371/journal.pone.0010903)

Goldberg, D. E., Janse, C.J., Cowman, A. F. and Waters, A.P. (2010) Has the time come for us to complement our malaria parasites? Trends in Parasitology, 27(1), pp. 1-2. (doi:10.1016/j.pt.2010.06.017)

Janse, C.J., Kroeze, H., van Wigcheren, A., Mededovic, S., Fonager, J., Franke-Fayard, B., Waters, A.P. and Khan, S.H. (2010) A genotype and phenotype database of genetically modified malaria-parasites. Trends in Parasitology, 27(1), pp. 31-39. (doi:10.1016/j.pt.2010.06.016)

Mair, G.R. et al. (2010) Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development. PLoS Pathogens, 6(2), e1000767. (doi:10.1371/journal.ppat.1000767)

Ploemen, I.H.J. et al. (2010) Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. PLoS ONE, 4(11), e7881. (doi:10.1371/journal.pone.0007881)

Spaccapelo, R. et al. (2010) Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria. American Journal of Pathology, 176(1), pp. 205-217. (doi:10.2353/ajpath.2010.090504)

2009

Ponzi, M. et al. (2009) Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein. Cellular Microbiology, 11(8), pp. 1272-1288. (doi:10.1111/j.1462-5822.2009.01331.x)

Tufet-Bayona, M., Janse, C.J., Khan, S.M., Waters, A.P., Sinden, R.E. and Franke-Fayard, B. (2009) Localisation and timing of expression of putative Plasmodium berghei rhoptry proteins in merozoites and sporozoites. Molecular and Biochemical Parasitology, 166(1), pp. 22-31. (doi:10.1016/j.molbiopara.2009.02.009)

Vega-Rodriguez, J., Franke-Fayard, B., Dinglasan, R.R., Janse, C.J., Pastrana-Mena, R., Rodriguez-Orengo, J.F., Jacobs-Lorena, M., Serrano, A.E., Waters, A. and Srinivasan, P. (2009) The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission. PLoS Pathogens, 5(2), e1000302. (doi:10.1371/journal.ppat.1000302)

Baum, J., Papenfuss, A.T., Mair, G.R., Janse, C.J., Vlachou, D., Waters, A.P., Cowman, A.F., Crabb, B.S. and Koning-Ward, T.F. (2009) Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites. Nucleic Acids Research, 37(11), pp. 3788-3798. (doi:10.1093/nar/gkp239)

Dobson, S. E., Augustijn, K. D., Brannigan, J. A., Schnick, C., Janse, C. J., Dodson, E. J., Waters, A.P. and Wilkinson, A. J. (2009) The crystal structures of macrophage migration inhibitory factor fromPlasmodium falciparumandPlasmodium berghei. Protein Science, 18(12), pp. 2578-2591. (doi:10.1002/pro.263)

Lavazec, C., Moreira, C.K., Mair, G.R., Waters, A.P., Janse, C.J. and Templeton, T.J. (2009) Analysis of mutant Plasmodium berghei parasites lacking expression of multiple PbCCp genes. Molecular and Biochemical Parasitology, 163(1), pp. 1-7. (doi:10.1016/j.molbiopara.2008.09.002)

Moon, R.W., Taylor, C.J., Bex, C., Schepers, R., Goulding, D., Janse, C.J., Waters, A.P., Baker, D.A. and Billker, O. (2009) A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. PLoS Pathogens, 5(9), e1000599. (doi:10.1371/journal.ppat.1000599)

Yuda, M., Iwanaga, S., Shigenobu, S., Mair, G.R., Janse, C.J., Waters, A.P., Kato, T. and Kaneko, I. (2009) Identification of a transcription factor in the mosquito-invasive stage of malaria parasites. Molecular Microbiology, 71(6), pp. 1402-1414. (doi:10.1111/j.1365-2958.2009.06609.x)

2008

Yu, M. et al. (2008) The fatty acid biosynthesis enzyme fabi plays a key role in the development of liver stage malarial parasites. Cell Host and Microbe, 4(6), pp. 567-568. (doi:10.1016/j.chom.2008.11.001)

van Schaijk, B. C. L. et al. (2008) Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes. PLoS ONE, 3(10), e3549. (doi:10.1371/journal.pone.0003549)

Braks, J.A.M., Mair, G.R., Franke-Fayard, B., Janse, C.J. and Waters, A.P. (2008) A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes. Nucleic Acids Research, 36(4), pp. 1176-1186. (doi:10.1093/nar/gkm1142)

Di Girolamo, F. et al. (2008) Plasmodium lipid rafts contain proteins implicated in vesicular trafficking and signalling as well as members of the PIR superfamily, potentially implicated in host immune system interactions. Proteomics, 8(12), pp. 2500-2513. (doi:10.1002/pmic.200700763)

Franke-Fayard, B., Djokovic, D., Dooren, M.W., Ramesar, J., Waters, A.P., Falade, M.O., Kranendonk, M., Martinelli, A., Cravo, P. and Janse, C.J. (2008) Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites. International Journal for Parasitology, 38(14), pp. 1651-1662. (doi:10.1016/j.ijpara.2008.05.012)

Lasonder, E. et al. (2008) Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity. PLoS Pathogens, 4(10), e1000195. (doi:10.1371/journal.ppat.1000195)

Moreira, C.K., Templeton, T.J., Lavazec, C., Hayward, R.E., Hobbs, C.V., Kroeze, H., Janse, C.J., Waters, A.P., Sinnis, P. and Coppi, A. (2008) The Plasmodium TRAPMIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Cellular Microbiology, 10(7), pp. 1505-1516. (doi:10.1111/j.1462-5822.2008.01143.x)

Waters, A.P. (2008) Genome-informed contributions to malaria therapies: feeding somewhere down the (pipe)line. Cell Host and Microbe, 3(5), pp. 280-283. (doi:10.1016/j.chom.2008.04.005)

van Ooij, C. et al. (2008) The malaria secretome: from algorithms to essential function in blood stage infection. PLoS Pathogens, 4(6), e1000084. (doi:10.1371/journal.ppat.1000084)

This list was generated on Sun Nov 19 16:04:58 2017 GMT.
Jump to: Articles
Number of items: 60.

Articles

Waters, A.P. and Bechtsi, D.P. (2017) Genomics and epigenetics of sexual commitment in Plasmodium. International Journal for Parasitology, 47(7), pp. 425-434. (doi:10.1016/j.ijpara.2017.03.002) (PMID:28455236)

Hughes, K. R. and Waters, A. P. (2017) Rapid inducible protein displacement in Plasmodiumin vivo and in vitro using knocksideways technology. Wellcome Open Research, 2, 18. (doi:10.12688/wellcomeopenres.11005.1) (PMID:28428983) (PMCID:PMC5395084)

Srivastava, A., Philip, N., Hughes, K. R., Georgiou, K., MacRae, J. I., Barrett, M. P. , Creek, D. J., McConville, M. J. and Waters, A. P. (2016) Stage-specific changes in plasmodium metabolism required for differentiation and adaptation to different host and vector environments. PLoS Pathogens, 12(12), e1006094. (doi:10.1371/journal.ppat.1006094) (PMID:28027318) (PMCID:PMC5189940)

Kirchner, S., Power, B. J. and Waters, A. P. (2016) Recent advances in malaria genomics and epigenomics. Genome Medicine, 8, 92. (doi:10.1186/s13073-016-0343-7) (PMID:27605022) (PMCID:PMC5015228)

Fairlamb, A. H., Gow, N. A.R., Matthews, K. R. and Waters, A. P. (2016) Drug resistance in eukaryotic microorganisms. Nature Microbiology, 1, 16092. (doi:10.1038/nmicrobiol.2016.92) (PMID:27572976) (PMCID:PMC5215055)

Kenthirapalan, S., Waters, A. P., Matuschewski, K. and Kooij, T. W. A. (2016) Functional profiles of orphan membrane transporters in the life cycle of the malaria parasite. Nature Communications, 7, 10519. (doi:10.1038/ncomms10519) (PMID:26796412) (PMCID:PMC4736113)

Waters, A. (2016) Epigenetic roulette in blood stream plasmodium: gambling on sex. PLoS Pathogens, 12(2), e1005353. (doi:10.1371/journal.ppat.1005353) (PMID:26866803) (PMCID:PMC4750958)

Philip, N. and Waters, A. P. (2015) Conditional degradation of plasmodium calcineurin reveals functions in parasite colonization of both host and vector. Cell Host and Microbe, 18(1), pp. 122-131. (doi:10.1016/j.chom.2015.05.018) (PMID:26118994) (PMCID:PMC4509507)

Srivastava, A., Creek, D. J., Evans, K. J., De Souza, D., Schofield, L., Muller, S., Barrett, M. P., McConville, M. J. and Waters, A. P. (2015) Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites. PLoS Pathogens, 11(6), e1004882. (doi:10.1371/journal.ppat.1004882) (PMID:26042734) (PMCID:PMC4456406)

Tampaki, Z., Mwakubambanya, R. S., Goulielmaki, E., Kaforou, S., Kim, K., Waters, A. P., Carruthers, V. B., Siden-Kiamos, I., Loukeris, T. G. and Koussis, K. (2015) Ectopic expression of a Neospora caninum Kazal type inhibitor triggers developmental defects in Toxoplasma and Plasmodium. PLoS ONE, 10(3), e0121379. (doi:10.1371/journal.pone.0121379) (PMID:25803874) (PMCID:PMC4372514)

Otto, T. D. et al. (2014) A comprehensive evaluation of rodent malaria parasite genomes and gene expression. BMC Biology, 12(1), p. 86. (doi:10.1186/s12915-014-0086-0) (PMID:25359557) (PMCID:PMC4242472)

Religa, A., Ramesar, J., Janse, C. J., Scherf, A. and Waters, A. P. (2014) P. berghei telomerase subunit TERT is essential for parasite survival. PLoS ONE, 9(10), e108930. (doi:10.1371/journal.pone.0108930)

Frischknecht, F., Mota, M., Scherf, A. and Waters, A. (2014) Biology of the Malaria Parasite - editorial on the special issue for the 10th BioMalPar conference. Cellular Microbiology, 16(5), pp. 599-601. (doi:10.1111/cmi.12295)

Sinha, A. et al. (2014) A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium. Nature, 507(7491), pp. 253-257. (doi:10.1038/nature12970) (PMID:24572359) (PMCID:PMC4105895)

Kenthirapalan, S., Waters, A. P., Matuschewski, K. and Kooij, T. W. A. (2014) Copper-transporting ATPase is important for malaria parasite fertility. Molecular Microbiology, 91(2), pp. 315-325. (doi:10.1111/mmi.12461)

Philip, N. and Waters, A. P. (2013) Unveiling the malaria parasite's cloak of invisibility? Science, 340(6135), pp. 936-937. (doi:10.1126/science.1239146)

Lin, J.-W. et al. (2013) Loss-of-function analyses defines vital and redundant functions of the plasmodiumrhomboid protease family. Molecular Microbiology, 88(2), pp. 318-338. (doi:10.1111/mmi.12187)

Philip, N., Orr, R. and Waters, A.P. (2013) Transfection of rodent malaria parasites. Methods in Molecular Biology, 923, pp. 99-125.

Waters, A.P. (2013) EVIMalaR — a model for international cooperation in scientific research. Nature Reviews Microbiology, 11(8), pp. 505-506. (doi:10.1038/nrmicro3079)

Kenthirapalan, S., Waters, A.P., Matuschewski, K. and Kooij, T.W. (2012) Flow cytometry-assisted rapid isolation of recombinant Plasmodium berghei parasites exemplified by functional analysis of aquaglyceroporin. International Journal for Parasitology, 42(13-14), pp. 1185-1192. (doi:10.1016/j.ijpara.2012.10.006)

Religa, A.A. and Waters, A.P. (2012) Sirtuins of parasitic protozoa: in search of function(s). Molecular and Biochemical Parasitology, 185(2), pp. 71-88. (doi:10.1016/j.molbiopara.2012.08.003)

Reboud, J., Bourquin, Y., Wilson, R., Pall, G.S., Jiwaji, M., Pitt, A.R., Graham, A., Waters, A.P. and Cooper, J.M. (2012) Shaping acoustic fields as a toolset for microfluidic manipulations in diagnostic technologies. Proceedings of the National Academy of Sciences of the United States of America, 109(38), pp. 15162-15167. (doi:10.1073/pnas.1206055109)

Crabb, B. S., Beeson, J. G., Amino, R., Ménard, R., Waters, A., Winzeler, E. A., Wahlgren, M., Fidock, D. A. and Nwaka, S. (2012) Perspectives: the missing pieces. Nature, 484(7395), S22-S23. (doi:10.1038/484S22a)

Khan, S. M., Reece, S. E., Waters, A. P., Janse, C. J. and Kaczanowski, S. (2012) Why are male malaria parasites in such a rush?: Sex-specific evolution and host-parasite interactions. Evolution, Medicine, and Public Health, 2013(1), pp. 3-13. (doi:10.1093/emph/eos003) (PMID:24481180) (PMCID:PMC4183958)

Orr, R.Y., Philip, N. and Waters, A.P. (2012) Improved negative selection protocol for Plasmodium berghei in the rodent malarial model. Malaria Journal, 11(103), (doi:10.1186/1475-2875-11-103)

Philip, N., Vaikkinen, H.J., Tetley, L. and Waters, A.P. (2012) A unique kelch domain phosphatase in plasmodium regulates ookinete morphology, motility and invasion. PLoS ONE, 7(9), e44617. (doi:10.1371/journal.pone.0044617)

Ramakrishnan, C., Rademacher, A., Soichot, J., Costa, G., Waters, A.P., Janse, C.J., Ramesar, J., Franke-Fayard, B.M. and Levashina, E.A. (2012) Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes. PLoS ONE, 7(5), e36376. (doi:10.1371/journal.pone.0036376)

Laurentino, E.C. et al. (2011) Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility. Cellular Microbiology, 13(12), pp. 1956-1974. (doi:10.1111/j.1462-5822.2011.01683.x)

Fonager, J., Franke-Fayard, B.M.D., Adams, J.H., Ramesar, J., Klop, O., Khan, S.M., Janse, C.J. and Waters, A.P. (2011) Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites. BMC Genomics, 12(155), pp. 1-17. (doi:10.1186/1471-2164-12-155)

Gomes-Santos, C.S.S. et al. (2011) Transition of plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein pumilio. PLoS Pathogens, 7(5), e1002046. (doi:10.1371/journal.ppat.1002046)

Hills, T., Srivastava, A., Ayi, K., Wernimont, A.K., Kain, K., Waters, A.P., Hui, R. and Pizarro, J.C. (2011) Characterization of a new phosphatase from Plasmodium. Molecular and Biochemical Parasitology, 179(2), pp. 69-79. (doi:10.1016/j.molbiopara.2011.06.001)

Sicard, A. et al. (2011) Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes. Cellular Microbiology, 13(6), pp. 836-845. (doi:10.1111/j.1462-5822.2011.01582.x)

Wykes, M.N. et al. (2011) Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11205-11210. (doi:10.1073/pnas.1108579108)

Hughes, K.R., Philip, N., Lucas Starnes, G., Taylor, S. and Waters, A.P. (2010) From cradle to grave: RNA biology in malaria parasites. Wiley Interdisciplinary Reviews: RNA, 1(2), pp. 287-303. (doi:10.1002/wrna.30)

van Dijk, M.R. et al. (2010) Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility. PLoS Pathogens, 6(6), e1000853. (doi:10.1371/journal.ppat.1000853)

Iwanaga, S., Khan, S.M., Kaneko, I., Christodoulou, Z., Newbold, C.N., Yuda, M., Janse, C.J. and Waters, A.P. (2010) Functional identification of the Plasmodium centromere and generation of a Plasmodium artificial chromosome. Cell Host and Microbe, 7(3), pp. 245-255. (doi:10.1016/j.chom.2010.02.010)

Starnes, G. L. and Waters, A.P. (2010) Home improvements: how the malaria parasite makes the red blood cell home sweet home. Journal of Molecular Cell Biology, 2(1), pp. 11-13. (doi:10.1093/jmcb/mjp024)

Bopp, S.E.R. et al. (2010) Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-γ as contributing to enhanced malaria surviva. PLoS ONE, 5(5), e10903. (doi:10.1371/journal.pone.0010903)

Goldberg, D. E., Janse, C.J., Cowman, A. F. and Waters, A.P. (2010) Has the time come for us to complement our malaria parasites? Trends in Parasitology, 27(1), pp. 1-2. (doi:10.1016/j.pt.2010.06.017)

Janse, C.J., Kroeze, H., van Wigcheren, A., Mededovic, S., Fonager, J., Franke-Fayard, B., Waters, A.P. and Khan, S.H. (2010) A genotype and phenotype database of genetically modified malaria-parasites. Trends in Parasitology, 27(1), pp. 31-39. (doi:10.1016/j.pt.2010.06.016)

Mair, G.R. et al. (2010) Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development. PLoS Pathogens, 6(2), e1000767. (doi:10.1371/journal.ppat.1000767)

Ploemen, I.H.J. et al. (2010) Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. PLoS ONE, 4(11), e7881. (doi:10.1371/journal.pone.0007881)

Spaccapelo, R. et al. (2010) Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria. American Journal of Pathology, 176(1), pp. 205-217. (doi:10.2353/ajpath.2010.090504)

Ponzi, M. et al. (2009) Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein. Cellular Microbiology, 11(8), pp. 1272-1288. (doi:10.1111/j.1462-5822.2009.01331.x)

Tufet-Bayona, M., Janse, C.J., Khan, S.M., Waters, A.P., Sinden, R.E. and Franke-Fayard, B. (2009) Localisation and timing of expression of putative Plasmodium berghei rhoptry proteins in merozoites and sporozoites. Molecular and Biochemical Parasitology, 166(1), pp. 22-31. (doi:10.1016/j.molbiopara.2009.02.009)

Vega-Rodriguez, J., Franke-Fayard, B., Dinglasan, R.R., Janse, C.J., Pastrana-Mena, R., Rodriguez-Orengo, J.F., Jacobs-Lorena, M., Serrano, A.E., Waters, A. and Srinivasan, P. (2009) The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission. PLoS Pathogens, 5(2), e1000302. (doi:10.1371/journal.ppat.1000302)

Baum, J., Papenfuss, A.T., Mair, G.R., Janse, C.J., Vlachou, D., Waters, A.P., Cowman, A.F., Crabb, B.S. and Koning-Ward, T.F. (2009) Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites. Nucleic Acids Research, 37(11), pp. 3788-3798. (doi:10.1093/nar/gkp239)

Dobson, S. E., Augustijn, K. D., Brannigan, J. A., Schnick, C., Janse, C. J., Dodson, E. J., Waters, A.P. and Wilkinson, A. J. (2009) The crystal structures of macrophage migration inhibitory factor fromPlasmodium falciparumandPlasmodium berghei. Protein Science, 18(12), pp. 2578-2591. (doi:10.1002/pro.263)

Lavazec, C., Moreira, C.K., Mair, G.R., Waters, A.P., Janse, C.J. and Templeton, T.J. (2009) Analysis of mutant Plasmodium berghei parasites lacking expression of multiple PbCCp genes. Molecular and Biochemical Parasitology, 163(1), pp. 1-7. (doi:10.1016/j.molbiopara.2008.09.002)

Moon, R.W., Taylor, C.J., Bex, C., Schepers, R., Goulding, D., Janse, C.J., Waters, A.P., Baker, D.A. and Billker, O. (2009) A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. PLoS Pathogens, 5(9), e1000599. (doi:10.1371/journal.ppat.1000599)

Yuda, M., Iwanaga, S., Shigenobu, S., Mair, G.R., Janse, C.J., Waters, A.P., Kato, T. and Kaneko, I. (2009) Identification of a transcription factor in the mosquito-invasive stage of malaria parasites. Molecular Microbiology, 71(6), pp. 1402-1414. (doi:10.1111/j.1365-2958.2009.06609.x)

Yu, M. et al. (2008) The fatty acid biosynthesis enzyme fabi plays a key role in the development of liver stage malarial parasites. Cell Host and Microbe, 4(6), pp. 567-568. (doi:10.1016/j.chom.2008.11.001)

van Schaijk, B. C. L. et al. (2008) Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes. PLoS ONE, 3(10), e3549. (doi:10.1371/journal.pone.0003549)

Braks, J.A.M., Mair, G.R., Franke-Fayard, B., Janse, C.J. and Waters, A.P. (2008) A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes. Nucleic Acids Research, 36(4), pp. 1176-1186. (doi:10.1093/nar/gkm1142)

Di Girolamo, F. et al. (2008) Plasmodium lipid rafts contain proteins implicated in vesicular trafficking and signalling as well as members of the PIR superfamily, potentially implicated in host immune system interactions. Proteomics, 8(12), pp. 2500-2513. (doi:10.1002/pmic.200700763)

Franke-Fayard, B., Djokovic, D., Dooren, M.W., Ramesar, J., Waters, A.P., Falade, M.O., Kranendonk, M., Martinelli, A., Cravo, P. and Janse, C.J. (2008) Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites. International Journal for Parasitology, 38(14), pp. 1651-1662. (doi:10.1016/j.ijpara.2008.05.012)

Lasonder, E. et al. (2008) Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity. PLoS Pathogens, 4(10), e1000195. (doi:10.1371/journal.ppat.1000195)

Moreira, C.K., Templeton, T.J., Lavazec, C., Hayward, R.E., Hobbs, C.V., Kroeze, H., Janse, C.J., Waters, A.P., Sinnis, P. and Coppi, A. (2008) The Plasmodium TRAPMIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Cellular Microbiology, 10(7), pp. 1505-1516. (doi:10.1111/j.1462-5822.2008.01143.x)

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This list was generated on Sun Nov 19 16:04:58 2017 GMT.