Dr Alfredo Castello

  • Senior Lecturer (Centre for Virus Research)

email: Alfredo.Castello@glasgow.ac.uk

MRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, 464 Bearsden Road, Glasgow, G61 1QH

ORCID iDhttps://orcid.org/0000-0002-1499-4662

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2009 | 2008 | 2007 | 2006
Number of items: 55.

2021

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, (doi: 10.1126/science.abj3624) (PMID:34581622) (Early Online Publication)

Iselin, L., Palmalux, N., Kamel, W., Simmonds, P., Mohammed, S. and Castello, A. (2021) Uncovering viral RNA-host cell interactions on a proteome-wide scale. Trends in Biochemical Sciences, (doi: 10.1016/j.tibs.2021.08.002) (Early Online Publication)

Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)

Kamel, W. et al. (2021) Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection. Molecular Cell, 81(13), 2851-2867.e7. (doi: 10.1016/j.molcel.2021.05.023) (PMID:34118193) (PMCID:PMC8142890)

Wing, P. A.C. et al. (2021) Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells. Cell Reports, 35(3), 109020. (doi: 10.1016/j.celrep.2021.109020) (PMID:33852916) (PMCID:PMC8020087)

Perez-Perri, J. I., Noerenberg, M. , Kamel, W., Lenz, C. E., Mohammed, S., Hentze, M. W. and Castello, A. (2021) Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture. Nature Protocols, 16, pp. 27-60. (doi: 10.1038/s41596-020-00404-1) (PMID:33208978) (PMCID:PMC7116560)

2020

Truman, C. T.-S., Järvelin, A., Davis, I. and Castello, A. (2020) HIV rev-isited. Open Biology, 10(12), 200320. (doi: 10.1098/rsob.200320) (PMID:33352061) (PMCID:PMC7776567)

Kilchert, C., Kecman, T., Priest, E., Hester, S., Aydin, E., Kus, K., Rossbach, O., Castello, A. , Mohammad, S. and Vasiljeva, L. (2020) System-wide analyses of the fission yeast poly(A)+ RNA interactome reveal insights into organization and function of RNA–protein complexes. Genome Research, 30(7), pp. 1012-1026. (doi: 10.1101/gr.257006.119) (PMID:32554781)

Bach-Pages, M., Homma, F., Kourelis, J., Kaschani, F., Mohammed, S., Kaiser, M., van der Hoorn, R. A.L., Castello, A. and Preston, G. M. (2020) Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture method. Biomolecules, 10(4), 661. (doi: 10.3390/biom10040661) (PMID:32344669) (PMCID:PMC7226388)

2019

Garcia-Moreno, M. et al. (2019) System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection. Molecular Cell, 74(1), pp. 196-211. (doi: 10.1016/j.molcel.2019.01.017) (PMID:30799147) (PMCID:PMC6458987)

Horos, R. et al. (2019) The small non-coding vault RNA1-1 acts as a riboregulator of autophagy. Cell, 176(5), 1054-1067.e12. (doi: 10.1016/j.cell.2019.01.030) (PMID:30773316)

2018

Avolio, R. et al. (2018) Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Research, 46(22), pp. 12067-12086. (doi: 10.1093/nar/gky873) (PMID:30260431) (PMCID:PMC6294507)

Garcia-Moreno, M., Järvelin, A. I. and Castello, A. (2018) Unconventional RNA-binding proteins step into the virus-host battlefront. Wiley Interdisciplinary Reviews: RNA, 9(6), e1498. (doi: 10.1002/wrna.1498) (PMID:30091184) (PMCID:PMC7169762)

Hentze, M. W., Castello, A. , Schwarzl, T. and Preiss, T. (2018) A brave new world of RNA-binding proteins. Nature Reviews Molecular Cell Biology, 19(5), pp. 327-341. (doi: 10.1038/nrm.2017.130) (PMID:29339797)

Hobor, F., Dallmann, A., Ball, N. J., Cicchini, C., Battistelli, C., Ogrodowicz, R. W., Christodoulou, E., Martin, S. R. and Castello, A. (2018) A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nature Communications, 9, 831. (doi: 10.1038/s41467-018-03182-3) (PMID:29483512) (PMCID:PMC5827114)

Moore, S., Järvelin, A. I., Davis, I., Bond, G. L. and Castello, A. (2018) Expanding horizons: new roles for non-canonical RNA-binding proteins in cancer. Current Opinion in Genetics and Development, 48, pp. 112-120. (doi: 10.1016/j.gde.2017.11.006) (PMID:29216518) (PMCID:PMC5894799)

2017

Pintacuda, G. et al. (2017) hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish polycomb-mediated chromosomal silencing. Molecular Cell, 68(5), 955-969.e10. (doi: 10.1016/j.molcel.2017.11.013) (PMID:29220657) (PMCID:PMC5735038)

Castello, A. , Frese, C. K., Fischer, B., Järvelin, A. I., Horos, R., Alleaume, A.-M., Foehr, S., Curk, T., Krijgsveld, J. and Hentze, M. W. (2017) Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap. Nature Protocols, 12(12), pp. 2447-2464. (doi: 10.1038/nprot.2017.106) (PMID:29095441)

Quintas, A., Pérez-Núñez, D., Sánchez, E. G., Nogal, M. L., Hentze, M. W., Castelló, A. and Revilla, Y. (2017) Characterization of the African swine fever virus decapping enzyme during infection. Journal of Virology, 91(24), e00990-17. (doi: 10.1128/JVI.00990-17) (PMID:29021398) (PMCID:PMC5709586)

Choudhury, N. R. et al. (2017) RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. BMC Biology, 15, (doi: 10.1186/s12915-017-0444-9) (PMID:29117863) (PMCID:PMC5678581)

Rogell, B., Fischer, B., Rettel, M., Krijgsveld, J., Castello, A. and Hentze, M. W. (2017) Specific RNP capture with antisense LNA/DNA mixmers. RNA, 23(8), pp. 1290-1302. (doi: 10.1261/rna.060798.117) (PMID:28476952) (PMCID:PMC5513073)

Bach-Pages, M., Castello, A. and Preston, G. M. (2017) Plant RNA interactome capture: revealing the plant RBPome. Trends in Plant Science, 22(6), pp. 449-451. (doi: 10.1016/j.tplants.2017.04.006) (PMID:28478905)

2016

Castello, A. , Fischer, B., Frese, C. K., Horos, R., Alleaume, A.-M., Foehr, S., Curk, T., Krijgsveld, J. and Hentze, M. W. (2016) Comprehensive identification of RNA-binding domains in human cells. Molecular Cell, 63(4), pp. 696-710. (doi: 10.1016/j.molcel.2016.06.029) (PMID:27453046) (PMCID:PMC5003815)

Liao, Y. et al. (2016) The cardiomyocyte RNA-binding proteome: links to intermediary metabolism and heart disease. Cell Reports, 16(5), pp. 1456-1469. (doi: 10.1016/j.celrep.2016.06.084) (PMID:27452465) (PMCID:PMC4977271)

Liepelt, A. et al. (2016) Identification of RNA-binding proteins in macrophages by interactome capture. Molecular and Cellular Proteomics, 15(8), pp. 2699-2714. (doi: 10.1074/mcp.M115.056564) (PMID:27281784) (PMCID:PMC4974345)

Sysoev, V. O., Fischer, B., Frese, C. K., Gupta, I., Krijgsveld, J., Hentze, M. W., Castello, A. and Ephrussi, A. (2016) Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila. Nature Communications, 7, 12128. (doi: 10.1038/ncomms12128) (PMID:27378189) (PMCID:PMC4935972)

Beckmann, B. M., Castello, A. and Medenbach, J. (2016) The expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactions. Pflügers Archiv European Journal of Physiology, 468(6), pp. 1029-1040. (doi: 10.1007/s00424-016-1819-4) (PMID:27165283) (PMCID:PMC4893068)

Järvelin, A. I., Noerenberg, M., Davis, I. and Castello, A. (2016) The new (dis)order in RNA regulation. Cell Communication and Signaling, 14, 9. (doi: 10.1186/s12964-016-0132-3) (PMID:27048167) (PMCID:PMC4822317)

Castello, A. , Horos, R., Strein, C., Fischer, B., Eichelbaum, K., Steinmetz, L. M., Krijgsveld, J. and Hentze, M. W. (2016) Comprehensive identification of RNA-binding proteins by RNA interactome capture. In: Dassi, E. (ed.) Post-Transcriptional Gene Regulation. Series: Methods in molecular biology (1358). Humana Press: New York, NY, pp. 131-139. ISBN 9781493930661 (doi:10.1007/978-1-4939-3067-8_8)

2015

Beckmann, B. M. et al. (2015) The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs. Nature Communications, 6, 10127. (doi: 10.1038/ncomms10127) (PMID:26632259) (PMCID:PMC4686815)

Castello, A. , Hentze, M. W. and Preiss, T. (2015) Metabolic enzymes enjoying new partnerships as RNA-binding proteins. Trends in Endocrinology and Metabolism, 26(12), pp. 746-757. (doi: 10.1016/j.tem.2015.09.012) (PMID:26520658) (PMCID:PMC4671484)

Castello, A. (2015) The emerging universe of RNA-binding proteins. Biochemist, 37(2), pp. 33-38. (doi: 10.1042/BIO03702033)

2014

Strein, C., Alleaume, A.-M., Rothbauer, U., Hentz, M. W. and Castello, A. (2014) A versatile assay for RNA-binding proteins in living cells. RNA, 20(5), pp. 721-731. (doi: 10.1261/rna.043562.113) (PMID:24664470) (PMCID:PMC3988573)

2013

Álvarez, E., Castelló, A. , Carrasco, L. and Izquierdo, J. M. (2013) Poliovirus 2A protease triggers a selective nucleo-cytoplasmic redistribution of splicing factors to regulate alternative pre-mRNA splicing. PLoS ONE, 8(9), e73723. (doi: 10.1371/journal.pone.0073723) (PMID:24066065) (PMCID:PMC3774746)

Kwon, S. C., Yi, H., Eichelbaum, K., Föhr, S., Fischer, B., You, K. T., Castello, A. , Krijgsveld, J., Hentze, M. W. and Kim, V. N. (2013) The RNA-binding protein repertoire of embryonic stem cells. Nature Structural and Molecular Biology, 20(9), pp. 1122-1130. (doi: 10.1038/nsmb.2638) (PMID:23912277)

Castello, A. , Fischer, B., Hentze, M. W. and Preiss, T. (2013) RNA-binding proteins in Mendelian disease. Trends in Genetics, 29(5), pp. 318-327. (doi: 10.1016/j.tig.2013.01.004) (PMID:23415593)

Sánchez, E. G., Quintas, A., Nogal, M., Castelló, A. and Revilla, Y. (2013) African swine fever virus controls the host transcription and cellular machinery of protein synthesis. Virus Research, 173(1), pp. 58-75. (doi: 10.1016/j.virusres.2012.10.025) (PMID:23154157)

Castello, A. , Horos, R., Strein, C., Fischer, B., Eichelbaum, K., Steinmetz, L. M., Krijgsveld, J. and Hentze, M. W. (2013) System-wide identification of RNA-binding proteins by interactome capture. Nature Protocols, 8(3), pp. 491-500. (doi: 10.1038/nprot.2013.020) (PMID:23411631)

2012

del Pino, J., Jiménez, J. L., Ventoso, I., Castelló, A. , Muñoz-Fernández, M. Á., de Haro, C. and Berlanga, J. J. (2012) GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection. PLoS ONE, 7(10), e47272. (doi: 10.1371/journal.pone.0047272) (PMID:23110064) (PMCID:PMC3479103)

Castello, A. et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell, 149(6), pp. 1393-1406. (doi: 10.1016/j.cell.2012.04.031) (PMID:22658674)

Buzon, M. J. et al. (2012) A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors. Journal of Antimicrobial Chemotherapy, 67(1), pp. 32-38. (doi: 10.1093/jac/dkr433) (PMID:21994909)

2011

Álvarez, E., Castelló, A. , Carrasco, L. and Izquierdo, J. M. (2011) Alternative splicing, a new target to block cellular gene expression by poliovirus 2A protease. Biochemical and Biophysical Research Communications, 414(1), pp. 142-147. (doi: 10.1016/j.bbrc.2011.09.040) (PMID:21945619)

Yángüez, E., Castello, A. , Welnowska, E., Carrasco, L., Goodfellow, I. and Nieto, A. (2011) Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation. Virology, 413(1), pp. 93-102. (doi: 10.1016/j.virol.2011.02.012) (PMID:21377182)

Castelló, A. , Álvarez, E. and Carrasco, L. (2011) The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases. Journal of Biomedicine and Biotechnology, 2011, 369648. (doi: 10.1155/2011/369648) (PMID:21541224) (PMCID:PMC3085340)

2009

Welnowska, E., Castello, A. , Moral, P. and Carrascó, L. (2009) Translation of mRNAs from Vesicular Stomatitis Virus and Vaccinia Virus Is Differentially Blocked in Cells with Depletion of eIF4GI and/or eIF4GII. Journal of Molecular Biology, 394(3), pp. 506-521. (doi: 10.1016/j.jmb.2009.09.036) (PMID:19769989)

Castelló, A. , Franco, D., Moral-López, P., Berlanga, J. J., Álvarez, E., Wimmer, E. and Carrasco, L. (2009) HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage. PLoS ONE, 4(11), e7997. (doi: 10.1371/journal.pone.0007997) (PMID:19956697) (PMCID:PMC2776998)

Castelló, A. , Izquierdo, J. M., Welnowska, E. and Carrasco, L. (2009) RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with nucleoporin cleavage. Journal of Cell Science, 122(20), pp. 3799-3809. (doi: 10.1242/jcs.055988) (PMID:19789179)

Castelló, A. , Quintas, A., Sánchez, E. G., Sabina, P., Nogal, M., Carrasco, L. and Revilla, Y. (2009) Regulation of host translational machinery by African swine fever virus. PLoS Pathogens, 5(8), e1000562. (doi: 10.1371/journal.ppat.1000562) (PMID:19714237) (PMCID:PMC2727446)

Sanz, M. Á., Castelló, A. , Ventoso, I., Berlanga, J. J. and Carrasco, L. (2009) Dual mechanism for the translation of subgenomic mRNA from Sindbis virus in infected and uninfected cells. PLoS ONE, 4(3), e4772. (doi: 10.1371/journal.pone.0004772) (PMID:19274090) (PMCID:PMC2651626)

2008

Madan, V., Castelló, A. and Carrasco, L. (2008) Viroporins from RNA viruses induce caspase-dependent apoptosis. Cellular Microbiology, 10(2), pp. 437-451. (doi: 10.1111/j.1462-5822.2007.01057.x) (PMID:17961183) (PMCID:PMC7162385)

2007

Molina, S., Sanz, M. A., Madan, V., Ventoso, I., Castello, A. and Carrasco, L. (2007) Differential inhibition of cellular and Sindbis virus translation by brefeldin A. Virology, 363(2), pp. 430-436. (doi: 10.1016/j.virol.2007.02.001) (PMID:17360015)

Sanz, M. A., Castelló, A. and Carrasco, L. (2007) Viral translation is coupled to transcription in Sindbis virus-infected cells. Journal of Virology, 81(13), pp. 7061-7068. (doi: 10.1128/JVI.02529-06) (PMID:17442713) (PMCID:PMC1933293)

2006

Castelló, A. , Alvarez, E. and Carrasco, L. (2006) Differential cleavage of eIF4GI and eIF4GII in mammalian cells: effects on translation. Journal of Biological Chemistry, 281(44), pp. 33206-33216. (doi: 10.1074/jbc.m604340200) (PMID:16959778)

Álvarez, E., Castello, A. , Menéndez-Arias, L. and Carrasco, L. (2006) HIV protease cleaves poly(A)-binding protein. Biochemical Journal, 396(2), pp. 219-226. (doi: 10.1042/BJ20060108) (PMID:16594896) (PMCID:PMC1462710)

Castelló, A. , Sanz, M. Á., Molina, S. and Carrasco, L. (2006) Translation of Sindbis virus 26S mRNA does not require intact eukariotic initiation factor 4G. Journal of Molecular Biology, 355(5), pp. 942-956. (doi: 10.1016/j.jmb.2005.11.024) (PMID:16343528)

This list was generated on Mon Oct 25 23:06:37 2021 BST.
Number of items: 55.

Articles

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, (doi: 10.1126/science.abj3624) (PMID:34581622) (Early Online Publication)

Iselin, L., Palmalux, N., Kamel, W., Simmonds, P., Mohammed, S. and Castello, A. (2021) Uncovering viral RNA-host cell interactions on a proteome-wide scale. Trends in Biochemical Sciences, (doi: 10.1016/j.tibs.2021.08.002) (Early Online Publication)

Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)

Kamel, W. et al. (2021) Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection. Molecular Cell, 81(13), 2851-2867.e7. (doi: 10.1016/j.molcel.2021.05.023) (PMID:34118193) (PMCID:PMC8142890)

Wing, P. A.C. et al. (2021) Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells. Cell Reports, 35(3), 109020. (doi: 10.1016/j.celrep.2021.109020) (PMID:33852916) (PMCID:PMC8020087)

Perez-Perri, J. I., Noerenberg, M. , Kamel, W., Lenz, C. E., Mohammed, S., Hentze, M. W. and Castello, A. (2021) Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture. Nature Protocols, 16, pp. 27-60. (doi: 10.1038/s41596-020-00404-1) (PMID:33208978) (PMCID:PMC7116560)

Truman, C. T.-S., Järvelin, A., Davis, I. and Castello, A. (2020) HIV rev-isited. Open Biology, 10(12), 200320. (doi: 10.1098/rsob.200320) (PMID:33352061) (PMCID:PMC7776567)

Kilchert, C., Kecman, T., Priest, E., Hester, S., Aydin, E., Kus, K., Rossbach, O., Castello, A. , Mohammad, S. and Vasiljeva, L. (2020) System-wide analyses of the fission yeast poly(A)+ RNA interactome reveal insights into organization and function of RNA–protein complexes. Genome Research, 30(7), pp. 1012-1026. (doi: 10.1101/gr.257006.119) (PMID:32554781)

Bach-Pages, M., Homma, F., Kourelis, J., Kaschani, F., Mohammed, S., Kaiser, M., van der Hoorn, R. A.L., Castello, A. and Preston, G. M. (2020) Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture method. Biomolecules, 10(4), 661. (doi: 10.3390/biom10040661) (PMID:32344669) (PMCID:PMC7226388)

Garcia-Moreno, M. et al. (2019) System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection. Molecular Cell, 74(1), pp. 196-211. (doi: 10.1016/j.molcel.2019.01.017) (PMID:30799147) (PMCID:PMC6458987)

Horos, R. et al. (2019) The small non-coding vault RNA1-1 acts as a riboregulator of autophagy. Cell, 176(5), 1054-1067.e12. (doi: 10.1016/j.cell.2019.01.030) (PMID:30773316)

Avolio, R. et al. (2018) Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Research, 46(22), pp. 12067-12086. (doi: 10.1093/nar/gky873) (PMID:30260431) (PMCID:PMC6294507)

Garcia-Moreno, M., Järvelin, A. I. and Castello, A. (2018) Unconventional RNA-binding proteins step into the virus-host battlefront. Wiley Interdisciplinary Reviews: RNA, 9(6), e1498. (doi: 10.1002/wrna.1498) (PMID:30091184) (PMCID:PMC7169762)

Hentze, M. W., Castello, A. , Schwarzl, T. and Preiss, T. (2018) A brave new world of RNA-binding proteins. Nature Reviews Molecular Cell Biology, 19(5), pp. 327-341. (doi: 10.1038/nrm.2017.130) (PMID:29339797)

Hobor, F., Dallmann, A., Ball, N. J., Cicchini, C., Battistelli, C., Ogrodowicz, R. W., Christodoulou, E., Martin, S. R. and Castello, A. (2018) A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nature Communications, 9, 831. (doi: 10.1038/s41467-018-03182-3) (PMID:29483512) (PMCID:PMC5827114)

Moore, S., Järvelin, A. I., Davis, I., Bond, G. L. and Castello, A. (2018) Expanding horizons: new roles for non-canonical RNA-binding proteins in cancer. Current Opinion in Genetics and Development, 48, pp. 112-120. (doi: 10.1016/j.gde.2017.11.006) (PMID:29216518) (PMCID:PMC5894799)

Pintacuda, G. et al. (2017) hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish polycomb-mediated chromosomal silencing. Molecular Cell, 68(5), 955-969.e10. (doi: 10.1016/j.molcel.2017.11.013) (PMID:29220657) (PMCID:PMC5735038)

Castello, A. , Frese, C. K., Fischer, B., Järvelin, A. I., Horos, R., Alleaume, A.-M., Foehr, S., Curk, T., Krijgsveld, J. and Hentze, M. W. (2017) Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap. Nature Protocols, 12(12), pp. 2447-2464. (doi: 10.1038/nprot.2017.106) (PMID:29095441)

Quintas, A., Pérez-Núñez, D., Sánchez, E. G., Nogal, M. L., Hentze, M. W., Castelló, A. and Revilla, Y. (2017) Characterization of the African swine fever virus decapping enzyme during infection. Journal of Virology, 91(24), e00990-17. (doi: 10.1128/JVI.00990-17) (PMID:29021398) (PMCID:PMC5709586)

Choudhury, N. R. et al. (2017) RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. BMC Biology, 15, (doi: 10.1186/s12915-017-0444-9) (PMID:29117863) (PMCID:PMC5678581)

Rogell, B., Fischer, B., Rettel, M., Krijgsveld, J., Castello, A. and Hentze, M. W. (2017) Specific RNP capture with antisense LNA/DNA mixmers. RNA, 23(8), pp. 1290-1302. (doi: 10.1261/rna.060798.117) (PMID:28476952) (PMCID:PMC5513073)

Bach-Pages, M., Castello, A. and Preston, G. M. (2017) Plant RNA interactome capture: revealing the plant RBPome. Trends in Plant Science, 22(6), pp. 449-451. (doi: 10.1016/j.tplants.2017.04.006) (PMID:28478905)

Castello, A. , Fischer, B., Frese, C. K., Horos, R., Alleaume, A.-M., Foehr, S., Curk, T., Krijgsveld, J. and Hentze, M. W. (2016) Comprehensive identification of RNA-binding domains in human cells. Molecular Cell, 63(4), pp. 696-710. (doi: 10.1016/j.molcel.2016.06.029) (PMID:27453046) (PMCID:PMC5003815)

Liao, Y. et al. (2016) The cardiomyocyte RNA-binding proteome: links to intermediary metabolism and heart disease. Cell Reports, 16(5), pp. 1456-1469. (doi: 10.1016/j.celrep.2016.06.084) (PMID:27452465) (PMCID:PMC4977271)

Liepelt, A. et al. (2016) Identification of RNA-binding proteins in macrophages by interactome capture. Molecular and Cellular Proteomics, 15(8), pp. 2699-2714. (doi: 10.1074/mcp.M115.056564) (PMID:27281784) (PMCID:PMC4974345)

Sysoev, V. O., Fischer, B., Frese, C. K., Gupta, I., Krijgsveld, J., Hentze, M. W., Castello, A. and Ephrussi, A. (2016) Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila. Nature Communications, 7, 12128. (doi: 10.1038/ncomms12128) (PMID:27378189) (PMCID:PMC4935972)

Beckmann, B. M., Castello, A. and Medenbach, J. (2016) The expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactions. Pflügers Archiv European Journal of Physiology, 468(6), pp. 1029-1040. (doi: 10.1007/s00424-016-1819-4) (PMID:27165283) (PMCID:PMC4893068)

Järvelin, A. I., Noerenberg, M., Davis, I. and Castello, A. (2016) The new (dis)order in RNA regulation. Cell Communication and Signaling, 14, 9. (doi: 10.1186/s12964-016-0132-3) (PMID:27048167) (PMCID:PMC4822317)

Beckmann, B. M. et al. (2015) The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs. Nature Communications, 6, 10127. (doi: 10.1038/ncomms10127) (PMID:26632259) (PMCID:PMC4686815)

Castello, A. , Hentze, M. W. and Preiss, T. (2015) Metabolic enzymes enjoying new partnerships as RNA-binding proteins. Trends in Endocrinology and Metabolism, 26(12), pp. 746-757. (doi: 10.1016/j.tem.2015.09.012) (PMID:26520658) (PMCID:PMC4671484)

Castello, A. (2015) The emerging universe of RNA-binding proteins. Biochemist, 37(2), pp. 33-38. (doi: 10.1042/BIO03702033)

Strein, C., Alleaume, A.-M., Rothbauer, U., Hentz, M. W. and Castello, A. (2014) A versatile assay for RNA-binding proteins in living cells. RNA, 20(5), pp. 721-731. (doi: 10.1261/rna.043562.113) (PMID:24664470) (PMCID:PMC3988573)

Álvarez, E., Castelló, A. , Carrasco, L. and Izquierdo, J. M. (2013) Poliovirus 2A protease triggers a selective nucleo-cytoplasmic redistribution of splicing factors to regulate alternative pre-mRNA splicing. PLoS ONE, 8(9), e73723. (doi: 10.1371/journal.pone.0073723) (PMID:24066065) (PMCID:PMC3774746)

Kwon, S. C., Yi, H., Eichelbaum, K., Föhr, S., Fischer, B., You, K. T., Castello, A. , Krijgsveld, J., Hentze, M. W. and Kim, V. N. (2013) The RNA-binding protein repertoire of embryonic stem cells. Nature Structural and Molecular Biology, 20(9), pp. 1122-1130. (doi: 10.1038/nsmb.2638) (PMID:23912277)

Castello, A. , Fischer, B., Hentze, M. W. and Preiss, T. (2013) RNA-binding proteins in Mendelian disease. Trends in Genetics, 29(5), pp. 318-327. (doi: 10.1016/j.tig.2013.01.004) (PMID:23415593)

Sánchez, E. G., Quintas, A., Nogal, M., Castelló, A. and Revilla, Y. (2013) African swine fever virus controls the host transcription and cellular machinery of protein synthesis. Virus Research, 173(1), pp. 58-75. (doi: 10.1016/j.virusres.2012.10.025) (PMID:23154157)

Castello, A. , Horos, R., Strein, C., Fischer, B., Eichelbaum, K., Steinmetz, L. M., Krijgsveld, J. and Hentze, M. W. (2013) System-wide identification of RNA-binding proteins by interactome capture. Nature Protocols, 8(3), pp. 491-500. (doi: 10.1038/nprot.2013.020) (PMID:23411631)

del Pino, J., Jiménez, J. L., Ventoso, I., Castelló, A. , Muñoz-Fernández, M. Á., de Haro, C. and Berlanga, J. J. (2012) GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection. PLoS ONE, 7(10), e47272. (doi: 10.1371/journal.pone.0047272) (PMID:23110064) (PMCID:PMC3479103)

Castello, A. et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell, 149(6), pp. 1393-1406. (doi: 10.1016/j.cell.2012.04.031) (PMID:22658674)

Buzon, M. J. et al. (2012) A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors. Journal of Antimicrobial Chemotherapy, 67(1), pp. 32-38. (doi: 10.1093/jac/dkr433) (PMID:21994909)

Álvarez, E., Castelló, A. , Carrasco, L. and Izquierdo, J. M. (2011) Alternative splicing, a new target to block cellular gene expression by poliovirus 2A protease. Biochemical and Biophysical Research Communications, 414(1), pp. 142-147. (doi: 10.1016/j.bbrc.2011.09.040) (PMID:21945619)

Yángüez, E., Castello, A. , Welnowska, E., Carrasco, L., Goodfellow, I. and Nieto, A. (2011) Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation. Virology, 413(1), pp. 93-102. (doi: 10.1016/j.virol.2011.02.012) (PMID:21377182)

Castelló, A. , Álvarez, E. and Carrasco, L. (2011) The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases. Journal of Biomedicine and Biotechnology, 2011, 369648. (doi: 10.1155/2011/369648) (PMID:21541224) (PMCID:PMC3085340)

Welnowska, E., Castello, A. , Moral, P. and Carrascó, L. (2009) Translation of mRNAs from Vesicular Stomatitis Virus and Vaccinia Virus Is Differentially Blocked in Cells with Depletion of eIF4GI and/or eIF4GII. Journal of Molecular Biology, 394(3), pp. 506-521. (doi: 10.1016/j.jmb.2009.09.036) (PMID:19769989)

Castelló, A. , Franco, D., Moral-López, P., Berlanga, J. J., Álvarez, E., Wimmer, E. and Carrasco, L. (2009) HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage. PLoS ONE, 4(11), e7997. (doi: 10.1371/journal.pone.0007997) (PMID:19956697) (PMCID:PMC2776998)

Castelló, A. , Izquierdo, J. M., Welnowska, E. and Carrasco, L. (2009) RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with nucleoporin cleavage. Journal of Cell Science, 122(20), pp. 3799-3809. (doi: 10.1242/jcs.055988) (PMID:19789179)

Castelló, A. , Quintas, A., Sánchez, E. G., Sabina, P., Nogal, M., Carrasco, L. and Revilla, Y. (2009) Regulation of host translational machinery by African swine fever virus. PLoS Pathogens, 5(8), e1000562. (doi: 10.1371/journal.ppat.1000562) (PMID:19714237) (PMCID:PMC2727446)

Sanz, M. Á., Castelló, A. , Ventoso, I., Berlanga, J. J. and Carrasco, L. (2009) Dual mechanism for the translation of subgenomic mRNA from Sindbis virus in infected and uninfected cells. PLoS ONE, 4(3), e4772. (doi: 10.1371/journal.pone.0004772) (PMID:19274090) (PMCID:PMC2651626)

Madan, V., Castelló, A. and Carrasco, L. (2008) Viroporins from RNA viruses induce caspase-dependent apoptosis. Cellular Microbiology, 10(2), pp. 437-451. (doi: 10.1111/j.1462-5822.2007.01057.x) (PMID:17961183) (PMCID:PMC7162385)

Molina, S., Sanz, M. A., Madan, V., Ventoso, I., Castello, A. and Carrasco, L. (2007) Differential inhibition of cellular and Sindbis virus translation by brefeldin A. Virology, 363(2), pp. 430-436. (doi: 10.1016/j.virol.2007.02.001) (PMID:17360015)

Sanz, M. A., Castelló, A. and Carrasco, L. (2007) Viral translation is coupled to transcription in Sindbis virus-infected cells. Journal of Virology, 81(13), pp. 7061-7068. (doi: 10.1128/JVI.02529-06) (PMID:17442713) (PMCID:PMC1933293)

Castelló, A. , Alvarez, E. and Carrasco, L. (2006) Differential cleavage of eIF4GI and eIF4GII in mammalian cells: effects on translation. Journal of Biological Chemistry, 281(44), pp. 33206-33216. (doi: 10.1074/jbc.m604340200) (PMID:16959778)

Álvarez, E., Castello, A. , Menéndez-Arias, L. and Carrasco, L. (2006) HIV protease cleaves poly(A)-binding protein. Biochemical Journal, 396(2), pp. 219-226. (doi: 10.1042/BJ20060108) (PMID:16594896) (PMCID:PMC1462710)

Castelló, A. , Sanz, M. Á., Molina, S. and Carrasco, L. (2006) Translation of Sindbis virus 26S mRNA does not require intact eukariotic initiation factor 4G. Journal of Molecular Biology, 355(5), pp. 942-956. (doi: 10.1016/j.jmb.2005.11.024) (PMID:16343528)

Book Sections

Castello, A. , Horos, R., Strein, C., Fischer, B., Eichelbaum, K., Steinmetz, L. M., Krijgsveld, J. and Hentze, M. W. (2016) Comprehensive identification of RNA-binding proteins by RNA interactome capture. In: Dassi, E. (ed.) Post-Transcriptional Gene Regulation. Series: Methods in molecular biology (1358). Humana Press: New York, NY, pp. 131-139. ISBN 9781493930661 (doi:10.1007/978-1-4939-3067-8_8)

This list was generated on Mon Oct 25 23:06:37 2021 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • DRMOV
    European Commission
    2021 - 2021
     

Research datasets

Jump to: 2021
Number of items: 2.

2021

Wickenhagen, A., Sugrue, E. , Lytras, S., Kuchi, S., Noerenberg, M. , Turnbull, M. , Loney, C. , Herder, V., Allan, J., Jarmson, I., Cameron Ruiz, N., Varjak, M. , Pinto, R. , Lee, J. Y., Iselin, L., Palmalux, N., Stewart, D., Swingler, S., Greenwood, E. J. D., Crozier, T. W. M., Gu, Q. , Davies, E., Clohisey, S., Wang, B., Trindade Maranhã Costa, F., Santana, M. F., Carlos de Lima Ferreira, L., Murphy, L., Fawkes, A., Meynert, A., Grimes, G., ISARICC investigators, , Da Silva Filho, J. , Marti, M. , Hughes, J. , Stanton, R. J., Wang, E. C. Y., Ho, A. , Davis, I., Jarrett, R. , Castello, A. , Robertson, D. , Semple, M. G., Openshaw, P. J. M., Palmarini, M. , Lehner, P. J., Baillie, K., Rihn, S. and Wilson, S. (2021) A Prenylated dsRNA Sensor Protects Against Severe COVID-19. [Data Collection]

Shaw, A., Rihn, S. , Mollentze, N. , Wickenhagen, A., Stewart, D., Orton, R. , Kuchi, S., Bakshi, S., Collados Rodriguez, M. , Turnbull, M. , Busby, J. , Gu, Q. , Smollett, K., Bamford, C., Sugrue, E. , Johnson, P. , Da Silva Filipe, A. , Castello, A. , Streicker, D. , Robertson, D. , Palmarini, M. and Wilson, S. (2021) The 'antiviral state' has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. [Data Collection] (Unpublished)

This list was generated on Tue Oct 26 05:57:34 2021 BST.

Visit the Castello Group webpage