Mrs Margaret Nilsen

  • Technician (Institute of Molecular Cell & Systems Biology)
  • Affiliate (Institute of Cardiovascular & Medical Sciences)

telephone: 01413303801
email: Margaret.Nilsen@glasgow.ac.uk

Lab 241 Level 2, Institute of molecular, cell & systems biology, Davidson building, Glasgow G12 8QQ

Publications

List by: Type | Date

Jump to: 2019 | 2018 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005
Number of items: 22.

2019

Mair, K. M., Harvey, K. Y., Henry, A. D., Hillyard, D. Z., Nilsen, M. and MacLean, M. R. (2019) Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension. European Respiratory Journal, 53(6), 1801524. (doi: 10.1183/13993003.01524-2018) (PMID:30923189) (PMCID:PMC6581204)

Docherty, C. K., Nilsen, M. and MacLean, M. R. (2019) Influence of 2-methoxyestradiol and sex on hypoxia-induced pulmonary hypertension and hypoxia-inducible factor‐1‐α. Journal of the American Heart Association, 8(5), e011628. (doi: 10.1161/JAHA.118.011628) (PMID:30819028) (PMCID:PMC6474940)

2018

Dean, A., Gregorc, T., Docherty, C. K., Harvey, K. Y., Nilsen, M., Morrell, N. W. and MacLean, M. R. (2018) Role of the aryl hydrocarbon receptor in Sugen 5416-induced experimental pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology, 58(3), pp. 320-330. (doi: 10.1165/rcmb.2017-0260OC) (PMID:28956952)

2016

Hood, K. Y., Montezano, A. C., Harvey, A. P., Nilsen, M., MacLean, M. R. and Touyz, R. M. (2016) Nicotinamide adenine dinucleotide phosphate oxidase–mediated redox signaling and vascular remodeling by 16α-hydroxyestrone in human pulmonary artery cells. Hypertension, 68(3), pp. 796-808. (doi: 10.1161/HYPERTENSIONAHA.116.07668) (PMID:27402919) (PMCID:PMC4978604)

Dean, A., Nilsen, M., Loughlin, L., Salt, I. P. and MacLean, M. R. (2016) Metformin reverses development of pulmonary hypertension via aromatase inhibition. Hypertension, 68(2), pp. 446-454. (doi: 10.1161/HYPERTENSIONAHA.116.07353) (PMID:27296990)

Johansen, A. K. Z., Dean, A., Morecroft, I., Hood, K., Nilsen, M., Loughlin, L., Anagnostopoulou, A., Touyz, R. M. , White, K. and MacLean, M. R. (2016) The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1 pulmonary circulation. Pulmonary Circulation, 6(1), pp. 82-92. (doi: 10.1086/685023) (PMID:27162617) (PMCID:PMC4860551)

2015

Wallace, E. , Morrell, N. W., Yang, X. D., Long, L., Stevens, H., Nilsen, M., Loughlin, L., Mair, K. M., Baker, A. H. and MacLean, M. R. (2015) A sex-specific microRNA-96/5HT1B Axis influences development of pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 191(12), pp. 1432-1442. (doi: 10.1164/rccm.201412-2148OC) (PMID:25871906) (PMCID:PMC4476563)

Wright, A. F., Ewart, M.-A., Mair, K., Nilsen, M., Dempsie, Y., Loughlin, L. and MacLean, M. R. (2015) Oestrogen receptor alpha in pulmonary hypertension. Cardiovascular Research, 106(2), pp. 206-216. (doi: 10.1093/cvr/cvv106) (PMID:25765937) (PMCID:PMC4615797)

2014

Mair, K. M. et al. (2014) Sex-dependent influence of endogenous estrogen in pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 190(4), pp. 456-467. (doi: 10.1164/rccm.201403-0483OC) (PMID:24956156) (PMCID:PMC4214128)

2013

Dempsie, Y., MacRitchie, N.A., White, K., Morecroft, I., Wright, A.F., Nilsen, M., Loughlin, L., Mair, K.M. and MacLean, M.R. (2013) Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension. Cardiovascular Research, 99(1), pp. 24-34. (doi: 10.1093/cvr/cvt064) (PMID:23519266) (PMCID:PMC3687748)

2012

Morecroft, I., White, K., Caruso, P., Nilsen, M., Loughlin, L., Alba, R., Reynolds, P.N., Danilov, S.M., Baker, A.H. and MacLean, M.R. (2012) Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension. Molecular Therapy, 20(8), pp. 1516-1528. (doi: 10.1038/mt.2012.70)

White, K. et al. (2012) Activity of the Estrogen-Metabolizing Enzyme Cytochrome P450 1B1 Influences the Development of Pulmonary Arterial Hypertension. Circulation, 126(9), pp. 1087-1098. (doi: 10.1161/CIRCULATIONAHA.111.062927)

2011

Dempsie, Y., Nilsen, M., White, K., Mair, K., Loughlin, L., Ambartsumian, N., Rabinovitch, M. and MacLean, M. (2011) Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females. Respiratory Research, 12(1), p. 159. (doi: 10.1186/1465-9921-12-159)

White, K., Loughlin, L., Maqbool, Z., Nilsen, M., McClure, J. , Dempsie, Y., Baker, A. H. and MacLean, M. R. (2011) Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH. Physiological Genomics, 43(8), pp. 417-437. (doi: 10.1152/physiolgenomics.00249.2010)

White, K., Dempsie, Y., Nilsen, M., Wright, A. F., Loughlin, L. and MacLean, M. R. (2011) The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension. Cardiovascular Research, 90(2), pp. 373-382. (doi: 10.1093/cvr/cvq408)

2010

Morecroft, I., Pang, L., Baranowska, M., Nilsen, M., Loughlin, L., Dempsie, Y., Millet, C. and MacLean, M. R. (2010) In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension. Cardiovascular Research, 85(3), pp. 593-603. (doi: 10.1093/cvr/cvp306) (PMID:19736308)

Morecroft, I., Pang, L., Baranowska, M., Nilsen, M., Loughlin, L., Dempsie, Y., Millet, C. and MacLean, M. R. (2010) In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension. Cardiovascular Research, 85(3), pp. 593-603. (doi: 10.1093/cvr/cvp306)

2009

Morecroft, I., Murray, A., Nilsen, M., Gurney, A.M. and MacLean, M.R. (2009) Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension. British Journal of Pharmacology, 157(7), pp. 1241-1249. (doi: 10.1111/j.1476-5381.2009.00283.x)

2008

Dempsie, Y. et al. (2008) Converging Evidence in Support of the Serotonin Hypothesis of Dexfenfluramine-Induced Pulmonary Hypertension With Novel Transgenic Mice. Circulation, 117(22), pp. 2928-2937. (doi: 10.1161/CIRCULATIONAHA.108.767558)

2007

Morecroft, I., Dempsie, Y., Bader, M., Walther, D.J., Kotnik, K., Loughlin, L., Nilsen, M. and MacLean, M.R. (2007) Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension. Hypertension, 49, pp. 232-236. (doi: 10.1161/01.HYP.0000252210.58849.78)

2006

Deuchar, G.A., Morecroft, I., Dempsie, Y., Herold, N., Nilsen, M., Hicks, M.N. and MacLean, M.R. (2006) The in vivo effects of human urotensin II in the rabbit and rat pulmonary circulation: effects of experimental pulmonary hypertension. European Journal of Pharmacology, 537, pp. 135-142. (doi: 10.1016/j.ejphar.2006.03.025)

2005

Morecroft, I., Loughlin, L., Nilsen, M., Colston, J., Dempsie, Y., Sheward, J., Harmar, A. and MacLean, M.R. (2005) Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. Journal of Pharmacology and Experimental Therapeutics, 313, pp. 539-548. (doi: 10.1124/jpet.104.081182)

This list was generated on Tue Sep 15 13:18:10 2020 BST.
Jump to: Articles
Number of items: 22.

Articles

Mair, K. M., Harvey, K. Y., Henry, A. D., Hillyard, D. Z., Nilsen, M. and MacLean, M. R. (2019) Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension. European Respiratory Journal, 53(6), 1801524. (doi: 10.1183/13993003.01524-2018) (PMID:30923189) (PMCID:PMC6581204)

Docherty, C. K., Nilsen, M. and MacLean, M. R. (2019) Influence of 2-methoxyestradiol and sex on hypoxia-induced pulmonary hypertension and hypoxia-inducible factor‐1‐α. Journal of the American Heart Association, 8(5), e011628. (doi: 10.1161/JAHA.118.011628) (PMID:30819028) (PMCID:PMC6474940)

Dean, A., Gregorc, T., Docherty, C. K., Harvey, K. Y., Nilsen, M., Morrell, N. W. and MacLean, M. R. (2018) Role of the aryl hydrocarbon receptor in Sugen 5416-induced experimental pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology, 58(3), pp. 320-330. (doi: 10.1165/rcmb.2017-0260OC) (PMID:28956952)

Hood, K. Y., Montezano, A. C., Harvey, A. P., Nilsen, M., MacLean, M. R. and Touyz, R. M. (2016) Nicotinamide adenine dinucleotide phosphate oxidase–mediated redox signaling and vascular remodeling by 16α-hydroxyestrone in human pulmonary artery cells. Hypertension, 68(3), pp. 796-808. (doi: 10.1161/HYPERTENSIONAHA.116.07668) (PMID:27402919) (PMCID:PMC4978604)

Dean, A., Nilsen, M., Loughlin, L., Salt, I. P. and MacLean, M. R. (2016) Metformin reverses development of pulmonary hypertension via aromatase inhibition. Hypertension, 68(2), pp. 446-454. (doi: 10.1161/HYPERTENSIONAHA.116.07353) (PMID:27296990)

Johansen, A. K. Z., Dean, A., Morecroft, I., Hood, K., Nilsen, M., Loughlin, L., Anagnostopoulou, A., Touyz, R. M. , White, K. and MacLean, M. R. (2016) The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1 pulmonary circulation. Pulmonary Circulation, 6(1), pp. 82-92. (doi: 10.1086/685023) (PMID:27162617) (PMCID:PMC4860551)

Wallace, E. , Morrell, N. W., Yang, X. D., Long, L., Stevens, H., Nilsen, M., Loughlin, L., Mair, K. M., Baker, A. H. and MacLean, M. R. (2015) A sex-specific microRNA-96/5HT1B Axis influences development of pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 191(12), pp. 1432-1442. (doi: 10.1164/rccm.201412-2148OC) (PMID:25871906) (PMCID:PMC4476563)

Wright, A. F., Ewart, M.-A., Mair, K., Nilsen, M., Dempsie, Y., Loughlin, L. and MacLean, M. R. (2015) Oestrogen receptor alpha in pulmonary hypertension. Cardiovascular Research, 106(2), pp. 206-216. (doi: 10.1093/cvr/cvv106) (PMID:25765937) (PMCID:PMC4615797)

Mair, K. M. et al. (2014) Sex-dependent influence of endogenous estrogen in pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 190(4), pp. 456-467. (doi: 10.1164/rccm.201403-0483OC) (PMID:24956156) (PMCID:PMC4214128)

Dempsie, Y., MacRitchie, N.A., White, K., Morecroft, I., Wright, A.F., Nilsen, M., Loughlin, L., Mair, K.M. and MacLean, M.R. (2013) Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension. Cardiovascular Research, 99(1), pp. 24-34. (doi: 10.1093/cvr/cvt064) (PMID:23519266) (PMCID:PMC3687748)

Morecroft, I., White, K., Caruso, P., Nilsen, M., Loughlin, L., Alba, R., Reynolds, P.N., Danilov, S.M., Baker, A.H. and MacLean, M.R. (2012) Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension. Molecular Therapy, 20(8), pp. 1516-1528. (doi: 10.1038/mt.2012.70)

White, K. et al. (2012) Activity of the Estrogen-Metabolizing Enzyme Cytochrome P450 1B1 Influences the Development of Pulmonary Arterial Hypertension. Circulation, 126(9), pp. 1087-1098. (doi: 10.1161/CIRCULATIONAHA.111.062927)

Dempsie, Y., Nilsen, M., White, K., Mair, K., Loughlin, L., Ambartsumian, N., Rabinovitch, M. and MacLean, M. (2011) Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females. Respiratory Research, 12(1), p. 159. (doi: 10.1186/1465-9921-12-159)

White, K., Loughlin, L., Maqbool, Z., Nilsen, M., McClure, J. , Dempsie, Y., Baker, A. H. and MacLean, M. R. (2011) Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH. Physiological Genomics, 43(8), pp. 417-437. (doi: 10.1152/physiolgenomics.00249.2010)

White, K., Dempsie, Y., Nilsen, M., Wright, A. F., Loughlin, L. and MacLean, M. R. (2011) The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension. Cardiovascular Research, 90(2), pp. 373-382. (doi: 10.1093/cvr/cvq408)

Morecroft, I., Pang, L., Baranowska, M., Nilsen, M., Loughlin, L., Dempsie, Y., Millet, C. and MacLean, M. R. (2010) In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension. Cardiovascular Research, 85(3), pp. 593-603. (doi: 10.1093/cvr/cvp306) (PMID:19736308)

Morecroft, I., Pang, L., Baranowska, M., Nilsen, M., Loughlin, L., Dempsie, Y., Millet, C. and MacLean, M. R. (2010) In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension. Cardiovascular Research, 85(3), pp. 593-603. (doi: 10.1093/cvr/cvp306)

Morecroft, I., Murray, A., Nilsen, M., Gurney, A.M. and MacLean, M.R. (2009) Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension. British Journal of Pharmacology, 157(7), pp. 1241-1249. (doi: 10.1111/j.1476-5381.2009.00283.x)

Dempsie, Y. et al. (2008) Converging Evidence in Support of the Serotonin Hypothesis of Dexfenfluramine-Induced Pulmonary Hypertension With Novel Transgenic Mice. Circulation, 117(22), pp. 2928-2937. (doi: 10.1161/CIRCULATIONAHA.108.767558)

Morecroft, I., Dempsie, Y., Bader, M., Walther, D.J., Kotnik, K., Loughlin, L., Nilsen, M. and MacLean, M.R. (2007) Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension. Hypertension, 49, pp. 232-236. (doi: 10.1161/01.HYP.0000252210.58849.78)

Deuchar, G.A., Morecroft, I., Dempsie, Y., Herold, N., Nilsen, M., Hicks, M.N. and MacLean, M.R. (2006) The in vivo effects of human urotensin II in the rabbit and rat pulmonary circulation: effects of experimental pulmonary hypertension. European Journal of Pharmacology, 537, pp. 135-142. (doi: 10.1016/j.ejphar.2006.03.025)

Morecroft, I., Loughlin, L., Nilsen, M., Colston, J., Dempsie, Y., Sheward, J., Harmar, A. and MacLean, M.R. (2005) Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. Journal of Pharmacology and Experimental Therapeutics, 313, pp. 539-548. (doi: 10.1124/jpet.104.081182)

This list was generated on Tue Sep 15 13:18:10 2020 BST.