Dr Olivia Hamilton

  • Research Associate (MRC/CSO Social & Public Health Sciences Unit)

Biography

I am a Research Associate in the Inequalities in Health team at the MRC/CSO Social and Public Health Sciences Unit. Currently, I  analyse longitudinal cohort data and linked administrative datasets as part of the National Core Studies - a programme of research established to inform the COVID-19 pandemic response.

I joined the SPHSU in August 2020, having recently gained my PhD in Translational Neuroscience at The University of Edinburgh (supported by the Wellcome Trust). My thesis aimed to advance current understanding of the cognitive changes associated with cerebrovascular dysfunction in older age, specifically those associated with cerebral small vessel disease, a disease that causes approximately 20% of strokes worldwide and contributes to all major forms of dementia.

Previously, I completed a BA in English Language at Cardiff University, before gaining an MSc in Language Sciences (with specialisation in Linguistics with Neuroscience) at University College London. Prior to starting my PhD, I worked as a research assistant on the MARQUE project, investigating the quality of life of people with dementia living in care homes and trialling a staff training intervention for the management of agitation in residents with dementia.

Research interests

To date, my research has focused on the impact of cerebrovascular dysfunction on cognitive ageing and the development of stroke and dementia. I am interested in examining the social determinants of health and in the development of interventions to promote healthy physical and cognitive ageing, in partnership with the communities who are disproportionately affected by poor cerebrovascular health.

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2019 | 2018 | 2017
Number of items: 12.

2021

Hamilton, O.K.L. et al. (2021) Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort. Neurobiology of Aging, 105, pp. 25-34. (doi: 10.1016/j.neurobiolaging.2021.04.007) (PMID:34022536)

Hamilton, O. K. L. et al. (2021) Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 1936. Translational Psychiatry, 11, 376. (doi: 10.1038/s41398-021-01495-4) (PMID:34226517) (PMCID:PMC8257729)

Hamilton, O. K. and Wardlaw, J. M. (2021) Response to Schroeter ML, Letter, Small vessel disease and social cognition. Alzheimer's and Dementia, (doi: 10.1002/alz.12402) (PMID:34156150) (Early Online Publication)

Weaver, N. A. et al. (2021) Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts. Lancet Neurology, 20(6), pp. 448-459. (doi: 10.1016/S1474-4422(21)00060-0) (PMID:33901427)

Hamilton, O. K.L. , Backhouse, E. V., Janssen, E., Jochems, A. C. C., Maher, C., Ritakari, T. E., Stevenson, A. J., Xia, L., Deary, I. J. and Wardlaw, J. M. (2021) Cognitive impairment in sporadic cerebral small vessel disease: a systematic review and meta‐analysis. Alzheimer's and Dementia, 17(4), pp. 665-685. (doi: 10.1002/alz.12221) (PMID:33185327)

Clancy, U. et al. (2021) Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3. European Stroke Journal, 6(1), pp. 81-88. (doi: 10.1177/2396987320929617) (PMID:33817338) (PMCID:PMC7995323)

2020

Jochems, A. C.C. et al. (2020) Relationship between venules and perivascular spaces in sporadic small vessel diseases. Stroke, 51(5), pp. 1503-1506. (doi: 10.1161/STROKEAHA.120.029163) (PMID:32264759) (PMCID:PMC7185057)

Davies, C., Hamilton, O. K.L. , Hooley, M., Ritakari, T. E., Stevenson, A. J. and Wheater, E. N.W. (2020) Translational neuroscience: the state of the nation (a PhD student perspective). Brain Communications, 2(1), fcaa038. (doi: 10.1093/braincomms/fcaa038) (PMID:32671338) (PMCID:PMC7331125)

2019

Weaver, N. A. et al. (2019) The Meta VCI Map consortium for meta‐analyses on strategic lesion locations for vascular cognitive impairment using lesion‐symptom mapping: design and multicenter pilot study. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11(1), pp. 310-326. (doi: 10.1016/j.dadm.2019.02.007) (PMID:31011619) (PMCID:PMC6465616)

Hamilton, O. K.L. et al. (2019) An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort. International Journal of Obesity, 43(9), pp. 1795-1802. (doi: 10.1038/s41366-018-0262-3) (PMID:30842548) (PMCID:PMC6760607)

2018

Rapaport, P., Livingston, G., Hamilton, O. , Turner, R., Stringer, A., Robertson, S. and Cooper, C. (2018) How do care home staff understand, manage and respond to agitation in people with dementia? A qualitative study. BMJ Open, 8(6), e022260. (doi: 10.1136/bmjopen-2018-022260) (PMID:29961036) (PMCID:PMC6042579)

2017

Robertson, S., Cooper, C., Hoe, J., Hamilton, O. , Stringer, A. and Livingston, G. (2017) Proxy rated quality of life of care home residents with dementia: a systematic review. International Psychogeriatrics, 29(4), pp. 569-581. (doi: 10.1017/S1041610216002167) (PMID:28088926) (PMCID:PMC5964456)

This list was generated on Mon Sep 27 22:27:06 2021 BST.
Jump to: Articles
Number of items: 12.

Articles

Hamilton, O.K.L. et al. (2021) Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort. Neurobiology of Aging, 105, pp. 25-34. (doi: 10.1016/j.neurobiolaging.2021.04.007) (PMID:34022536)

Hamilton, O. K. L. et al. (2021) Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 1936. Translational Psychiatry, 11, 376. (doi: 10.1038/s41398-021-01495-4) (PMID:34226517) (PMCID:PMC8257729)

Hamilton, O. K. and Wardlaw, J. M. (2021) Response to Schroeter ML, Letter, Small vessel disease and social cognition. Alzheimer's and Dementia, (doi: 10.1002/alz.12402) (PMID:34156150) (Early Online Publication)

Weaver, N. A. et al. (2021) Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts. Lancet Neurology, 20(6), pp. 448-459. (doi: 10.1016/S1474-4422(21)00060-0) (PMID:33901427)

Hamilton, O. K.L. , Backhouse, E. V., Janssen, E., Jochems, A. C. C., Maher, C., Ritakari, T. E., Stevenson, A. J., Xia, L., Deary, I. J. and Wardlaw, J. M. (2021) Cognitive impairment in sporadic cerebral small vessel disease: a systematic review and meta‐analysis. Alzheimer's and Dementia, 17(4), pp. 665-685. (doi: 10.1002/alz.12221) (PMID:33185327)

Clancy, U. et al. (2021) Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3. European Stroke Journal, 6(1), pp. 81-88. (doi: 10.1177/2396987320929617) (PMID:33817338) (PMCID:PMC7995323)

Jochems, A. C.C. et al. (2020) Relationship between venules and perivascular spaces in sporadic small vessel diseases. Stroke, 51(5), pp. 1503-1506. (doi: 10.1161/STROKEAHA.120.029163) (PMID:32264759) (PMCID:PMC7185057)

Davies, C., Hamilton, O. K.L. , Hooley, M., Ritakari, T. E., Stevenson, A. J. and Wheater, E. N.W. (2020) Translational neuroscience: the state of the nation (a PhD student perspective). Brain Communications, 2(1), fcaa038. (doi: 10.1093/braincomms/fcaa038) (PMID:32671338) (PMCID:PMC7331125)

Weaver, N. A. et al. (2019) The Meta VCI Map consortium for meta‐analyses on strategic lesion locations for vascular cognitive impairment using lesion‐symptom mapping: design and multicenter pilot study. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11(1), pp. 310-326. (doi: 10.1016/j.dadm.2019.02.007) (PMID:31011619) (PMCID:PMC6465616)

Hamilton, O. K.L. et al. (2019) An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort. International Journal of Obesity, 43(9), pp. 1795-1802. (doi: 10.1038/s41366-018-0262-3) (PMID:30842548) (PMCID:PMC6760607)

Rapaport, P., Livingston, G., Hamilton, O. , Turner, R., Stringer, A., Robertson, S. and Cooper, C. (2018) How do care home staff understand, manage and respond to agitation in people with dementia? A qualitative study. BMJ Open, 8(6), e022260. (doi: 10.1136/bmjopen-2018-022260) (PMID:29961036) (PMCID:PMC6042579)

Robertson, S., Cooper, C., Hoe, J., Hamilton, O. , Stringer, A. and Livingston, G. (2017) Proxy rated quality of life of care home residents with dementia: a systematic review. International Psychogeriatrics, 29(4), pp. 569-581. (doi: 10.1017/S1041610216002167) (PMID:28088926) (PMCID:PMC5964456)

This list was generated on Mon Sep 27 22:27:06 2021 BST.

Professional activities & recognition

Selected international presentations

  • 2020: British Pharmacological Society Annual Conference: Pharmacology 2020 (Online due to COVID-19)
  • 2019: Joint World Stroke Organisation/European Stroke Organisation Conference (Milan, Italy)