Dr Marc Ciosi

  • Research Associate (Molecular Biosciences)

telephone: +44(0)1413306220
email: Marc.Ciosi@glasgow.ac.uk

Institute of MC & SB, Davidson building, Lab 412, Glasgow, G12 8qq

Import to contacts

ORCID iDhttps://orcid.org/0000-0002-7663-4080

Biography

I received an MSc and PhD in the field of Evolutionary and Population Genetics from the University of Nice, France. In 2014, after several years working on the genetics of various species, I joined Pr Darren Monckton’s group at the University of Glasgow as a postdoctoral researcher to work on CAG∙CTG repeat expansion loci with an emphasis on Huntington disease. My research focuses on identifying the determinants of CAG∙CTG repeats somatic instability and the consequences it has on disease outcomes.

Research experience:

2014 - present

Postdoctoral research associate (University of Glasgow, UK). High throughput sequencing and genotype-phenotype approaches to study the HTT CAG/CCG repeat and its somatic instability in Huntington disease.
2011 - 2014

Postdoctoral research associate (University of Glasgow, UK / ICIPE, Kenya). Population genetics and co-adaptation of trypanosomes with tsetse flies.
2009 - 2010

Research and teaching assistant (INRA / University of Nice, France). Research activity: molecular ecology of invasive species. Teaching activity: Population genetics, molecular evolution and phylogeny, analysis of DNA sequence polymorphism, supervision of master students

2006 - 2009 Ph.D. thesis: Invasion of Europe by the western corn rootworm, Diabrotica virgifera virgifera.
2005

Master’s thesis: Physiology and symbiont diversity associated with depth in Eunicella singularis, symbiotic sea fan of the Mediterranean Sea.

Research interests

General interests:

- Genetic variation

- The processes that modify and generate genetic variation (within individuals and populations as well as between populations)

- The phenotypic and evolutionnary consequences of genetic variation

 

Particular interests:

- Genotype-phenotype association

- Repeat expansion disorders with a focus on Huntington disease

- Technologies used to type genetic variants

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2014 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007
Number of items: 40.

2025

Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium, ORCID logoORCID: https://orcid.org/0000-0003-1601-5277, ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, ORCID logoORCID: https://orcid.org/0000-0003-2933-4808 and ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2025) Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease reveal shared and tissue-specific effects. Nature Genetics, 57(6), pp. 1426-1436. (doi: 10.1038/s41588-025-02191-5) (PMID:40490511)

Khan, A. et al. (2025) Swatting flies: Biting insects as non-invasive samplers for mammalian population genomics. Molecular Ecology, (doi: 10.1111/mec.17661) (PMID:39838904) (Early Online Publication)

Scahill, R. I. et al. (2025) Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis. Nature Medicine, (doi: 10.1038/s41591-024-03424-6) (PMID:39825149) (Early Online Publication)

2024

Lee, J.-M. et al. (2024) Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease reveal shared and tissue-specific effects. bioRxiv, (doi: 10.1101/2024.06.10.597797)

Kim, K.-H. et al. (2024) Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington’s disease. Proceedings of the National Academy of Sciences, 121(16), e232292412. (doi: 10.1073/pnas.2322924121) (PMID:38607933)

Ruiz de Sabando, Ainara, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Galbete, Arkaitz, Cumming, Sarah A., Spanish HD Collaborative Group, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Ramos-Arroyo, Maria A (2024) Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European Journal of Human Genetics, (doi: 10.1038/s41431-024-01546-6)

2023

Sabando, A. R. et al. (2023) Spanish HTT gene study reveals haplotype and allelic diversity with possible implications for germline expansion dynamics in Huntington disease. Human Molecular Genetics, 32(6), pp. 897-906. (doi: 10.1093/hmg/ddac224) (PMID:36130218) (PMCID:PMC9990985)

2022

Taylor, A. S. et al. (2022) Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing. NAR Genomics and Bioinformatics, 4(4), lqac089. (doi: 10.1093/nargab/lqac089) (PMID:36478959) (PMCID:PMC9719798)

Dawson, Jessica, Baine-Savanhu, Fiona K., Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Maxwell, Alastair ORCID logoORCID: https://orcid.org/0000-0002-2414-2252, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Krause, Amanda (2022) A probable cis-acting genetic modifier of Huntington disease frequent in individuals with African ancestry. Human Genetics and Genomics Advances, 3(4), 100130. (doi: 10.1016/j.xhgg.2022.100130) (PMID:35935919) (PMCID:PMC9352962)

Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Young, Robin, Kwak, Seung and Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2022) Longitudinal Analysis of Somatic Expansion of the HTT Repeat in Blood as a Potential Biomarker of Somatic Instability in Huntingon Disease. EHDN2022 Plenary Meeting - D: Wet biomarkers, Bologna, Italy, 16-18 September 2022. (doi: 10.1136/jnnp-2022-ehdn.57)

Ruiz de Sabando, Ainara, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Galbete, Arkaitz, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Ramos-Arroyo, Maria A. (2022) Somatic Mosaicism of the HTT Cag Repeat in Intermediate Allele Carriers with Neurocognitive Symptoms Compatible with Huntington Disease. EHDN2022 Plenary Meeting - A: Pathogenic mechanisms, Bologna, Italy, 16-18 September 2022. (doi: 10.1136/jnnp-2022-ehdn.1)

Lee, J.-M. et al. (2022) Genetic modifiers of Huntington disease differentially influence motor and cognitive domains. American Journal of Human Genetics, 109(5), pp. 885-899. (doi: 10.1016/j.ajhg.2022.03.004) (PMID:35325614)

McAllister, B. et al. (2022) Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset. Nature Neuroscience, 25(4), pp. 446-457. (doi: 10.1038/s41593-022-01033-5) (PMID:35379994)

2021

Channumsin, Manun, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Masiga, Dan, Auty, Harriet ORCID logoORCID: https://orcid.org/0000-0002-6181-3780, Turner, C. Michael, Kilbride, Elizabeth and Mable, Barbara K. ORCID logoORCID: https://orcid.org/0000-0001-7118-4116 (2021) Blood meal analysis of tsetse flies (Glossina pallidipes: Glossinidae) reveals higher host fidelity on wild compared with domestic hosts. Wellcome Open Research, 6, 213. (doi: 10.12688/wellcomeopenres.16978.1) (PMCID:PMC8513123)

Ciosi, M. et al. (2021) Approaches to sequence the HTT CAG repeat expansion and quantify repeat length variation. Journal of Huntington's Disease, 10(1), pp. 53-74. (doi: 10.3233/jhd-200433) (PMID:33579864) (PMCID:PMC7990409)

2020

Lu, A. T. et al. (2020) DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature Communications, 11, 4529. (doi: 10.1038/s41467-020-18255-5) (PMID:32913184) (PMCID:PMC7484780)

Ellis, N. et al. (2020) Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry, 87(9), pp. 857-865. (doi: 10.1016/j.biopsych.2019.12.010) (PMID:32087949)

2019

Ciosi, M. et al. (2019) A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes. EBioMedicine, 48, pp. 568-580. (doi: 10.1016/j.ebiom.2019.09.020) (PMID:31607598) (PMCID:PMC6838430)

Lee, J.-M. et al. (2019) CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell, 178(4), 887-900.e14. (doi: 10.1016/j.cell.2019.06.036)

Flower, M. et al. (2019) MSH3 modifies somatic instability and disease severity in Huntington's and myotonic dystrophy type 1. Brain, 142(7), pp. 1876-1886. (doi: 10.1093/brain/awz115) (PMID:31216018) (PMCID:PMC6598626)

2018

Channumsin, Manun, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Masiga, Dan, Turner, C. Michael R. and Mable, Barbara K. ORCID logoORCID: https://orcid.org/0000-0001-7118-4116 (2018) Sodalis glossinidius presence in wild tsetse is only associated with presence of trypanosomes in complex interactions with other tsetse-specific factors. BMC Microbiology, 18(Supp1.), 163. (doi: 10.1186/s12866-018-1285-6) (PMID:30470184) (PMCID:PMC6251152)

Ciosi, M. et al. (2018) Glutamine Codon Usage and Somatic Mosaicism of the HTT CAG Repeat Are Modifiers of Huntington Disease Severity. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Flower, Michael, Lomeikaite, Vilija, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Morales, Fernando, Lo, Kitty, Hensman Moss, Davina, Jones, Lesley, Holmans, Peter, Tabrizi, Sarah J. and Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2018) Genetic Variation in MSH3 That Lowers Its Expression Ameliorates Disease Course and Limits Repeat Expansion in Huntington’s Disease and Myotonic Dystrophy Type 1. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Ging, Heather, Nethisinghe, Suran, Chatzi, Afroditi, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Giunti, Paola (2018) Determining the CAG Repeat Mosaic in Post-mortem Human HD Brains. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Levesley, Jessica, Baine, Fiona, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Maxwell, Alastair ORCID logoORCID: https://orcid.org/0000-0002-2414-2252, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Krause, Amanda (2018) A CIS-acting Modifier of Age at Diagnosis of Huntington Disease in Black South African Patients. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Cumming, Sarah A., Alshammari, Asma Mubarak, Symeonidi, Efthymia, Herzyk, Pawel ORCID logoORCID: https://orcid.org/0000-0002-7439-292X, Mcguinness, David ORCID logoORCID: https://orcid.org/0000-0003-2947-2047, Galbraith, Julie, Hamilton, Graham and Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2018) Library preparation and MiSeq sequencing for the genotyping-by-sequencing of the Huntington disease HTT exon one trinucleotide repeat and the quantification of somatic mosaicism [Protocol]. Other. Springer Nature. (doi: 10.21203/rs.2.1581/v2).

Mugasa, Claire M., Villinger, Jandouwe, Gitau, Joseph, Ndungu, Nelly, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080 and Masiga, Daniel (2018) Morphological re-description and molecular identification of Tabanidae (Diptera) in East Africa. ZooKeys, 796, pp. 117-144. (doi: 10.3897/zookeys.769.21144) (PMID:29988760) (PMCID:PMC6030178)

Lombaert, Eric, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Miller, Nicholas J., Sappington, Thomas W., Blin, Aurélie and Guillemaud, Thomas (2018) Colonization history of the western corn rootworm (Diabrotica virgifera virgifera) in North America: insights from random forest ABC using microsatellite data. Biological Invasions, 20(3), pp. 665-677. (doi: 10.1007/s10530-017-1566-2)

2017

Ndungu, Nelly N., Kiatoko, Nkoba, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Salifu, Daisy, Nyansera, Damaris, Masiga, Daniel and Raina, Suresh K. (2017) Identification of stingless bees (Hymenoptera: Apidae) in Kenya using Morphometrics and DNA barcoding. Journal of Apicultural Research, 56(4), pp. 341-353. (doi: 10.1080/00218839.2017.1327939)

2016

Monckton, Darren ORCID logoORCID: https://orcid.org/0000-0002-8298-8264, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Mubarak, Asma, Cumming, Sarah, Hamilton, Graham, Maxwell, Alastair ORCID logoORCID: https://orcid.org/0000-0002-2414-2252, The International-Venezuela Collaborative Research Group, -, The Scottish Myotonic Dystrophy Genetic Variation Consortium, - and The Track-On HD Research Team, - (2016) Cryptic Polyglutamine Repeat Sequence Variation and Somatic Instability in Huntington’s Disease: Drivers of Pathology? European Huntington's Disease Network 9th Plenary Meeting, The Hague, The Netherlands, 16-18 Sep 2016. (doi: 10.1136/jnnp-2016-314597.2)

Isaac, Clement, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Hamilton, Alana, Scullion, Kathleen Maria, Dede, Peter, Igbinosa, Igho Benjamin, Nmorsi, Oyebiguwa Patrick Goddey, Masiga, Dan and Turner, C. Michael R. (2016) Molecular identification of different trypanosome species and subspecies in tsetse flies of northern Nigeria. Parasites and Vectors, 9, 301. (doi: 10.1186/s13071-016-1585-3) (PMID:27216812) (PMCID:PMC4877947)

2014

Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Masiga, Daniel K. and Turner, Charles M.R. (2014) Laboratory colonisation and genetic bottlenecks in the tsetse fly Glossina pallidipes. PLoS Neglected Tropical Diseases, 8(2), e2697. (doi: 10.1371/journal.pntd.0002697)

2012

Bermond, G., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Lombaert, E., Blin, A., Boriani, M., Furlan, L., Toepfer, S. and Guillemaud, T. (2012) Secondary contact and admixture between independently invading populations of the Western corn rootworm, diabrotica virgifera virgifera in Europe. PLoS ONE, 7(11), e50129. (doi: 10.1371/journal.pone.0050129) (PMID:23189184) (PMCID:PMC3506547)

2011

Guillemaud, T., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Lombaert, E. and Estoup, A. (2011) Biological invasions in agricultural settings: insights from evolutionary biology and population genetics. Comptes Rendus Biologies, 334(3), pp. 237-246. (doi: 10.1016/j.crvi.2010.12.008)

Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Miller, N.J., Toepfer, S., Estoup, A. and Guillemaud, T. (2011) Stratified dispersal and increasing genetic variation during the invasion of Central Europe by the western corn rootworm, Diabrotica virgifera virgifera. Evolutionary Applications, 4(1), pp. 57-70. (doi: 10.1111/j.1752-4571.2010.00133.x)

Forcioli, D., Merle, P.L., Caligara, C., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Muti, C., Francour, P., Cerrano, C. and Allemand, D. (2011) Symbiont diversity is not involved in depth acclimation in the Mediterranean sea whip Eunicella singularis. Marine Ecology Progress Series, 439, pp. 57-71. (doi: 10.3354/meps09314)

2010

Guillemaud, T., Beaumont, M.A., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Cornuet, J.-M. and Estoup, A. (2010) Inferring introduction routes of invasive species using approximate Bayesian computation on microsatellite data. Heredity, 104(1), pp. 88-99. (doi: 10.1038/hdy.2009.92)

2009

Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Toepfer, S., Li, H., Haye, T., Kuhlmann, U., Wang, H., Siegfried, B. and Guillemaud, T. (2009) European populations of Diabrotica virgifera virgifera are resistant to aldrin, but not to methyl-parathion. Journal of Applied Entomology, 133(4), pp. 307-314. (doi: 10.1111/j.1439-0418.2008.01363.x)

2008

Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Miller, N.J., Kim, K.S., Giordano, R., Estoup, A. and Guillemaud, T. (2008) Invasion of Europe by the western corn rootworm, Diabrotica virgifera virgifera: multiple transatlantic introductions with various reductions of genetic diversity. Molecular Ecology, 17(16), pp. 3614-3627. (doi: 10.1111/j.1365-294X.2008.03866.x)

2007

Miller, N.J., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Sappington, T.W., Ratcliffe, S.T., Spencer, J.L. and Guillemaud, T. (2007) Genome scan of Diabrotica virgifera virgifera for genetic variation associated with crop rotation tolerance. Journal of Applied Entomology, 131(6), pp. 378-385. (doi: 10.1111/j.1439-0418.2007.01190.x)

This list was generated on Sun Jun 29 20:42:19 2025 BST.
Jump to: Articles | Research Reports or Papers | Conference or Workshop Item
Number of items: 40.

Articles

Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium, ORCID logoORCID: https://orcid.org/0000-0003-1601-5277, ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, ORCID logoORCID: https://orcid.org/0000-0003-2933-4808 and ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2025) Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease reveal shared and tissue-specific effects. Nature Genetics, 57(6), pp. 1426-1436. (doi: 10.1038/s41588-025-02191-5) (PMID:40490511)

Khan, A. et al. (2025) Swatting flies: Biting insects as non-invasive samplers for mammalian population genomics. Molecular Ecology, (doi: 10.1111/mec.17661) (PMID:39838904) (Early Online Publication)

Scahill, R. I. et al. (2025) Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis. Nature Medicine, (doi: 10.1038/s41591-024-03424-6) (PMID:39825149) (Early Online Publication)

Lee, J.-M. et al. (2024) Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease reveal shared and tissue-specific effects. bioRxiv, (doi: 10.1101/2024.06.10.597797)

Kim, K.-H. et al. (2024) Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington’s disease. Proceedings of the National Academy of Sciences, 121(16), e232292412. (doi: 10.1073/pnas.2322924121) (PMID:38607933)

Ruiz de Sabando, Ainara, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Galbete, Arkaitz, Cumming, Sarah A., Spanish HD Collaborative Group, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Ramos-Arroyo, Maria A (2024) Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European Journal of Human Genetics, (doi: 10.1038/s41431-024-01546-6)

Sabando, A. R. et al. (2023) Spanish HTT gene study reveals haplotype and allelic diversity with possible implications for germline expansion dynamics in Huntington disease. Human Molecular Genetics, 32(6), pp. 897-906. (doi: 10.1093/hmg/ddac224) (PMID:36130218) (PMCID:PMC9990985)

Taylor, A. S. et al. (2022) Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing. NAR Genomics and Bioinformatics, 4(4), lqac089. (doi: 10.1093/nargab/lqac089) (PMID:36478959) (PMCID:PMC9719798)

Dawson, Jessica, Baine-Savanhu, Fiona K., Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Maxwell, Alastair ORCID logoORCID: https://orcid.org/0000-0002-2414-2252, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Krause, Amanda (2022) A probable cis-acting genetic modifier of Huntington disease frequent in individuals with African ancestry. Human Genetics and Genomics Advances, 3(4), 100130. (doi: 10.1016/j.xhgg.2022.100130) (PMID:35935919) (PMCID:PMC9352962)

Lee, J.-M. et al. (2022) Genetic modifiers of Huntington disease differentially influence motor and cognitive domains. American Journal of Human Genetics, 109(5), pp. 885-899. (doi: 10.1016/j.ajhg.2022.03.004) (PMID:35325614)

McAllister, B. et al. (2022) Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset. Nature Neuroscience, 25(4), pp. 446-457. (doi: 10.1038/s41593-022-01033-5) (PMID:35379994)

Channumsin, Manun, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Masiga, Dan, Auty, Harriet ORCID logoORCID: https://orcid.org/0000-0002-6181-3780, Turner, C. Michael, Kilbride, Elizabeth and Mable, Barbara K. ORCID logoORCID: https://orcid.org/0000-0001-7118-4116 (2021) Blood meal analysis of tsetse flies (Glossina pallidipes: Glossinidae) reveals higher host fidelity on wild compared with domestic hosts. Wellcome Open Research, 6, 213. (doi: 10.12688/wellcomeopenres.16978.1) (PMCID:PMC8513123)

Ciosi, M. et al. (2021) Approaches to sequence the HTT CAG repeat expansion and quantify repeat length variation. Journal of Huntington's Disease, 10(1), pp. 53-74. (doi: 10.3233/jhd-200433) (PMID:33579864) (PMCID:PMC7990409)

Lu, A. T. et al. (2020) DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature Communications, 11, 4529. (doi: 10.1038/s41467-020-18255-5) (PMID:32913184) (PMCID:PMC7484780)

Ellis, N. et al. (2020) Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry, 87(9), pp. 857-865. (doi: 10.1016/j.biopsych.2019.12.010) (PMID:32087949)

Ciosi, M. et al. (2019) A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes. EBioMedicine, 48, pp. 568-580. (doi: 10.1016/j.ebiom.2019.09.020) (PMID:31607598) (PMCID:PMC6838430)

Lee, J.-M. et al. (2019) CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell, 178(4), 887-900.e14. (doi: 10.1016/j.cell.2019.06.036)

Flower, M. et al. (2019) MSH3 modifies somatic instability and disease severity in Huntington's and myotonic dystrophy type 1. Brain, 142(7), pp. 1876-1886. (doi: 10.1093/brain/awz115) (PMID:31216018) (PMCID:PMC6598626)

Channumsin, Manun, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Masiga, Dan, Turner, C. Michael R. and Mable, Barbara K. ORCID logoORCID: https://orcid.org/0000-0001-7118-4116 (2018) Sodalis glossinidius presence in wild tsetse is only associated with presence of trypanosomes in complex interactions with other tsetse-specific factors. BMC Microbiology, 18(Supp1.), 163. (doi: 10.1186/s12866-018-1285-6) (PMID:30470184) (PMCID:PMC6251152)

Mugasa, Claire M., Villinger, Jandouwe, Gitau, Joseph, Ndungu, Nelly, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080 and Masiga, Daniel (2018) Morphological re-description and molecular identification of Tabanidae (Diptera) in East Africa. ZooKeys, 796, pp. 117-144. (doi: 10.3897/zookeys.769.21144) (PMID:29988760) (PMCID:PMC6030178)

Lombaert, Eric, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Miller, Nicholas J., Sappington, Thomas W., Blin, Aurélie and Guillemaud, Thomas (2018) Colonization history of the western corn rootworm (Diabrotica virgifera virgifera) in North America: insights from random forest ABC using microsatellite data. Biological Invasions, 20(3), pp. 665-677. (doi: 10.1007/s10530-017-1566-2)

Ndungu, Nelly N., Kiatoko, Nkoba, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Salifu, Daisy, Nyansera, Damaris, Masiga, Daniel and Raina, Suresh K. (2017) Identification of stingless bees (Hymenoptera: Apidae) in Kenya using Morphometrics and DNA barcoding. Journal of Apicultural Research, 56(4), pp. 341-353. (doi: 10.1080/00218839.2017.1327939)

Isaac, Clement, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Hamilton, Alana, Scullion, Kathleen Maria, Dede, Peter, Igbinosa, Igho Benjamin, Nmorsi, Oyebiguwa Patrick Goddey, Masiga, Dan and Turner, C. Michael R. (2016) Molecular identification of different trypanosome species and subspecies in tsetse flies of northern Nigeria. Parasites and Vectors, 9, 301. (doi: 10.1186/s13071-016-1585-3) (PMID:27216812) (PMCID:PMC4877947)

Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Masiga, Daniel K. and Turner, Charles M.R. (2014) Laboratory colonisation and genetic bottlenecks in the tsetse fly Glossina pallidipes. PLoS Neglected Tropical Diseases, 8(2), e2697. (doi: 10.1371/journal.pntd.0002697)

Bermond, G., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Lombaert, E., Blin, A., Boriani, M., Furlan, L., Toepfer, S. and Guillemaud, T. (2012) Secondary contact and admixture between independently invading populations of the Western corn rootworm, diabrotica virgifera virgifera in Europe. PLoS ONE, 7(11), e50129. (doi: 10.1371/journal.pone.0050129) (PMID:23189184) (PMCID:PMC3506547)

Guillemaud, T., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Lombaert, E. and Estoup, A. (2011) Biological invasions in agricultural settings: insights from evolutionary biology and population genetics. Comptes Rendus Biologies, 334(3), pp. 237-246. (doi: 10.1016/j.crvi.2010.12.008)

Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Miller, N.J., Toepfer, S., Estoup, A. and Guillemaud, T. (2011) Stratified dispersal and increasing genetic variation during the invasion of Central Europe by the western corn rootworm, Diabrotica virgifera virgifera. Evolutionary Applications, 4(1), pp. 57-70. (doi: 10.1111/j.1752-4571.2010.00133.x)

Forcioli, D., Merle, P.L., Caligara, C., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Muti, C., Francour, P., Cerrano, C. and Allemand, D. (2011) Symbiont diversity is not involved in depth acclimation in the Mediterranean sea whip Eunicella singularis. Marine Ecology Progress Series, 439, pp. 57-71. (doi: 10.3354/meps09314)

Guillemaud, T., Beaumont, M.A., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Cornuet, J.-M. and Estoup, A. (2010) Inferring introduction routes of invasive species using approximate Bayesian computation on microsatellite data. Heredity, 104(1), pp. 88-99. (doi: 10.1038/hdy.2009.92)

Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Toepfer, S., Li, H., Haye, T., Kuhlmann, U., Wang, H., Siegfried, B. and Guillemaud, T. (2009) European populations of Diabrotica virgifera virgifera are resistant to aldrin, but not to methyl-parathion. Journal of Applied Entomology, 133(4), pp. 307-314. (doi: 10.1111/j.1439-0418.2008.01363.x)

Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Miller, N.J., Kim, K.S., Giordano, R., Estoup, A. and Guillemaud, T. (2008) Invasion of Europe by the western corn rootworm, Diabrotica virgifera virgifera: multiple transatlantic introductions with various reductions of genetic diversity. Molecular Ecology, 17(16), pp. 3614-3627. (doi: 10.1111/j.1365-294X.2008.03866.x)

Miller, N.J., Ciosi, M. ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Sappington, T.W., Ratcliffe, S.T., Spencer, J.L. and Guillemaud, T. (2007) Genome scan of Diabrotica virgifera virgifera for genetic variation associated with crop rotation tolerance. Journal of Applied Entomology, 131(6), pp. 378-385. (doi: 10.1111/j.1439-0418.2007.01190.x)

Research Reports or Papers

Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Cumming, Sarah A., Alshammari, Asma Mubarak, Symeonidi, Efthymia, Herzyk, Pawel ORCID logoORCID: https://orcid.org/0000-0002-7439-292X, Mcguinness, David ORCID logoORCID: https://orcid.org/0000-0003-2947-2047, Galbraith, Julie, Hamilton, Graham and Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2018) Library preparation and MiSeq sequencing for the genotyping-by-sequencing of the Huntington disease HTT exon one trinucleotide repeat and the quantification of somatic mosaicism [Protocol]. Other. Springer Nature. (doi: 10.21203/rs.2.1581/v2).

Conference or Workshop Item

Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Young, Robin, Kwak, Seung and Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2022) Longitudinal Analysis of Somatic Expansion of the HTT Repeat in Blood as a Potential Biomarker of Somatic Instability in Huntingon Disease. EHDN2022 Plenary Meeting - D: Wet biomarkers, Bologna, Italy, 16-18 September 2022. (doi: 10.1136/jnnp-2022-ehdn.57)

Ruiz de Sabando, Ainara, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Galbete, Arkaitz, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Ramos-Arroyo, Maria A. (2022) Somatic Mosaicism of the HTT Cag Repeat in Intermediate Allele Carriers with Neurocognitive Symptoms Compatible with Huntington Disease. EHDN2022 Plenary Meeting - A: Pathogenic mechanisms, Bologna, Italy, 16-18 September 2022. (doi: 10.1136/jnnp-2022-ehdn.1)

Ciosi, M. et al. (2018) Glutamine Codon Usage and Somatic Mosaicism of the HTT CAG Repeat Are Modifiers of Huntington Disease Severity. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Flower, Michael, Lomeikaite, Vilija, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Morales, Fernando, Lo, Kitty, Hensman Moss, Davina, Jones, Lesley, Holmans, Peter, Tabrizi, Sarah J. and Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 (2018) Genetic Variation in MSH3 That Lowers Its Expression Ameliorates Disease Course and Limits Repeat Expansion in Huntington’s Disease and Myotonic Dystrophy Type 1. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Ging, Heather, Nethisinghe, Suran, Chatzi, Afroditi, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Giunti, Paola (2018) Determining the CAG Repeat Mosaic in Post-mortem Human HD Brains. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Levesley, Jessica, Baine, Fiona, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Maxwell, Alastair ORCID logoORCID: https://orcid.org/0000-0002-2414-2252, Monckton, Darren G. ORCID logoORCID: https://orcid.org/0000-0002-8298-8264 and Krause, Amanda (2018) A CIS-acting Modifier of Age at Diagnosis of Huntington Disease in Black South African Patients. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.

Monckton, Darren ORCID logoORCID: https://orcid.org/0000-0002-8298-8264, Ciosi, Marc ORCID logoORCID: https://orcid.org/0000-0002-7663-4080, Mubarak, Asma, Cumming, Sarah, Hamilton, Graham, Maxwell, Alastair ORCID logoORCID: https://orcid.org/0000-0002-2414-2252, The International-Venezuela Collaborative Research Group, -, The Scottish Myotonic Dystrophy Genetic Variation Consortium, - and The Track-On HD Research Team, - (2016) Cryptic Polyglutamine Repeat Sequence Variation and Somatic Instability in Huntington’s Disease: Drivers of Pathology? European Huntington's Disease Network 9th Plenary Meeting, The Hague, The Netherlands, 16-18 Sep 2016. (doi: 10.1136/jnnp-2016-314597.2)

This list was generated on Sun Jun 29 20:42:19 2025 BST.

Supervision

Teaching

Hands-on tutorial on the Galaxy web-based platform: Microsatellite genotyping from parallel sequencing reads spanning the repeat

21 and 23/11/2016 6 hours

25/07/2016 5 hours